Motif ID: YY1.p2

Z-value: 3.957


Transcription factors associated with YY1.p2:

Gene SymbolEntrez IDGene Name
Yy1 22632 YY1 transcription factor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Yy1chr12_+_1100315200.431.2e-09Click!


Activity profile for motif YY1.p2.

activity profile for motif YY1.p2


Sorted Z-values histogram for motif YY1.p2

Sorted Z-values for motif YY1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of YY1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_103236110 54.711


chr13_-_21925343 53.294 NM_178185
NM_001177544
 Hist1h2ah
Hist1h2ap
Hist1h2ai
Hist1h2ao
histone cluster 1, H2ah
histone cluster 1, H2ap
histone cluster 1, H2ai
histone cluster 1, H2ao
chr13_-_23663006 46.915 NM_178187
 Hist1h2ae
histone cluster 1, H2ae
chr11_-_116713532 42.272 Srsf2
serine/arginine-rich splicing factor 2
chr11_-_70468130 38.511 NM_011072
 Pfn1
profilin 1
chr11_-_70468061 38.253 Pfn1
profilin 1
chr11_-_115884885 38.199


chr11_-_70468019 37.196 Pfn1
profilin 1
chr10_+_79317316 36.204 NM_001077363
NM_008956
 Ptbp1

polypyrimidine tract binding protein 1

chr13_+_21902235 33.125 NM_178185
NM_001177544
 Hist1h2ah
Hist1h2ap
Hist1h2ai
Hist1h2ao
histone cluster 1, H2ah
histone cluster 1, H2ap
histone cluster 1, H2ai
histone cluster 1, H2ao
chr9_+_120864938 32.968 Ctnnb1
catenin (cadherin associated protein), beta 1
chr6_-_125112509 32.475 Gapdh
Gm5523
Gm10481
glyceraldehyde-3-phosphate dehydrogenase
glyceraldehyde-3-phosphate dehydrogenase pseudogene
glyceraldehyde-3-phosphate dehydrogenase pseudogene
chr13_-_21845695 32.395 NM_178183
 Hist1h2ak
histone cluster 1, H2ak
chr10_+_79317396 31.759 Ptbp1
polypyrimidine tract binding protein 1
chr13_-_22134795 25.912 NM_178186
 Hist1h2ag
Hist1h2ai
histone cluster 1, H2ag
histone cluster 1, H2ai
chr13_-_21879086 25.683 NM_178184
 Hist1h2an
histone cluster 1, H2an
chr6_-_88834347 24.293 Mcm2
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr13_+_23666249 23.172 NM_178188
 Hist1h2ad
Hist1h2ai
histone cluster 1, H2ad
histone cluster 1, H2ai
chr6_-_87793459 21.417 Cnbp
cellular nucleic acid binding protein
chr10_+_12728252 20.548 NM_175102
 Sf3b5
splicing factor 3b, subunit 5

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 268 entries
Enrichment   P-value GO Accession GO Term
3.77 7.58e-03 GO:0016180 snRNA processing
3.28 1.81e-24 GO:0006414 translational elongation
3.09 1.21e-02 GO:0043489 RNA stabilization
3.09 1.21e-02 GO:0048255 mRNA stabilization
3.05 3.35e-04 GO:0043488 regulation of mRNA stability
2.74 5.18e-03 GO:0043487 regulation of RNA stability
2.70 1.22e-09 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
2.70 4.16e-09 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.61 1.49e-08 GO:0051352 negative regulation of ligase activity
2.61 1.49e-08 GO:0051444 negative regulation of ubiquitin-protein ligase activity
2.55 5.14e-37 GO:0006412 translation
2.55 7.87e-08 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.52 1.05e-08 GO:0051443 positive regulation of ubiquitin-protein ligase activity
2.49 8.95e-08 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.46 3.87e-08 GO:0051351 positive regulation of ligase activity
2.43 1.65e-08 GO:0031397 negative regulation of protein ubiquitination
2.41 5.61e-13 GO:0042254 ribosome biogenesis
2.40 2.27e-08 GO:0051438 regulation of ubiquitin-protein ligase activity
2.34 7.25e-08 GO:0051340 regulation of ligase activity
2.32 2.17e-08 GO:0018205 peptidyl-lysine modification

Gene overrepresentation in compartment category:

Showing 1 to 20 of 96 entries
Enrichment   P-value GO Accession GO Term
4.11 7.12e-06 GO:0000314 organellar small ribosomal subunit
4.11 7.12e-06 GO:0005763 mitochondrial small ribosomal subunit
3.74 4.27e-03 GO:0032039 integrator complex
3.48 5.71e-03 GO:0005852 eukaryotic translation initiation factor 3 complex
3.31 3.49e-14 GO:0015935 small ribosomal subunit
3.15 4.46e-11 GO:0022626 cytosolic ribosome
3.09 1.94e-02 GO:0043596 nuclear replication fork
3.03 1.42e-06 GO:0022627 cytosolic small ribosomal subunit
3.03 5.59e-03 GO:0031519 PcG protein complex
2.97 1.31e-36 GO:0005840 ribosome
2.97 1.28e-06 GO:0005747 mitochondrial respiratory chain complex I
2.97 1.28e-06 GO:0030964 NADH dehydrogenase complex
2.97 1.28e-06 GO:0045271 respiratory chain complex I
2.94 1.10e-07 GO:0000313 organellar ribosome
2.94 1.10e-07 GO:0005761 mitochondrial ribosome
2.89 2.80e-08 GO:0005746 mitochondrial respiratory chain
2.82 2.77e-05 GO:0015934 large ribosomal subunit
2.82 4.21e-02 GO:0005839 proteasome core complex
2.77 1.37e-08 GO:0070469 respiratory chain
2.72 9.01e-09 GO:0000502 proteasome complex

Gene overrepresentation in function category:

Showing 1 to 20 of 85 entries
Enrichment   P-value GO Accession GO Term
3.25 1.05e-03 GO:0003954 NADH dehydrogenase activity
3.20 5.46e-31 GO:0003735 structural constituent of ribosome
3.20 3.45e-03 GO:0008137 NADH dehydrogenase (ubiquinone) activity
3.20 3.45e-03 GO:0050136 NADH dehydrogenase (quinone) activity
3.09 3.26e-03 GO:0016655 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
2.69 1.36e-02 GO:0019843 rRNA binding
2.68 4.78e-02 GO:0004402 histone acetyltransferase activity
2.68 4.78e-02 GO:0004468 lysine N-acetyltransferase activity
2.68 4.78e-02 GO:0016455 RNA polymerase II transcription mediator activity
2.35 4.13e-02 GO:0042054 histone methyltransferase activity
2.29 1.62e-05 GO:0008565 protein transporter activity
2.23 9.47e-04 GO:0003743 translation initiation factor activity
2.22 7.68e-03 GO:0043021 ribonucleoprotein binding
2.15 1.80e-05 GO:0003729 mRNA binding
2.14 2.78e-02 GO:0016651 oxidoreductase activity, acting on NADH or NADPH
2.12 1.51e-05 GO:0008135 translation factor activity, nucleic acid binding
2.08 1.81e-04 GO:0051082 unfolded protein binding
2.04 8.47e-45 GO:0003723 RNA binding
1.99 4.91e-04 GO:0003714 transcription corepressor activity
1.93 3.62e-11 GO:0000989 transcription factor binding transcription factor activity