Motif ID: YY1.p2

Z-value: 3.957


Transcription factors associated with YY1.p2:

Gene SymbolEntrez IDGene Name
Yy1 22632 YY1 transcription factor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Yy1chr12_+_1100315200.431.2e-09Click!


Activity profile for motif YY1.p2.

activity profile for motif YY1.p2


Sorted Z-values histogram for motif YY1.p2

Sorted Z-values for motif YY1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of YY1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_103236110 54.711


chr13_-_21925343 53.294 NM_178185
NM_001177544
Hist1h2ah
Hist1h2ap
Hist1h2ai
Hist1h2ao
histone cluster 1, H2ah
histone cluster 1, H2ap
histone cluster 1, H2ai
histone cluster 1, H2ao
chr13_-_23663006 46.915 NM_178187
Hist1h2ae
histone cluster 1, H2ae
chr11_-_116713532 42.272 Srsf2
serine/arginine-rich splicing factor 2
chr11_-_70468130 38.511 NM_011072
Pfn1
profilin 1
chr11_-_70468061 38.253 Pfn1
profilin 1
chr11_-_115884885 38.199


chr11_-_70468019 37.196 Pfn1
profilin 1
chr10_+_79317316 36.204 NM_001077363
NM_008956
Ptbp1

polypyrimidine tract binding protein 1

chr13_+_21902235 33.125 NM_178185
NM_001177544
Hist1h2ah
Hist1h2ap
Hist1h2ai
Hist1h2ao
histone cluster 1, H2ah
histone cluster 1, H2ap
histone cluster 1, H2ai
histone cluster 1, H2ao
chr9_+_120864938 32.968 Ctnnb1
catenin (cadherin associated protein), beta 1
chr6_-_125112509 32.475 Gapdh
Gm5523
Gm10481
glyceraldehyde-3-phosphate dehydrogenase
glyceraldehyde-3-phosphate dehydrogenase pseudogene
glyceraldehyde-3-phosphate dehydrogenase pseudogene
chr13_-_21845695 32.395 NM_178183
Hist1h2ak
histone cluster 1, H2ak
chr10_+_79317396 31.759 Ptbp1
polypyrimidine tract binding protein 1
chr13_-_22134795 25.912 NM_178186
Hist1h2ag
Hist1h2ai
histone cluster 1, H2ag
histone cluster 1, H2ai
chr13_-_21879086 25.683 NM_178184
Hist1h2an
histone cluster 1, H2an
chr6_-_88834347 24.293 Mcm2
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr13_+_23666249 23.172 NM_178188
Hist1h2ad
Hist1h2ai
histone cluster 1, H2ad
histone cluster 1, H2ai
chr6_-_87793459 21.417 Cnbp
cellular nucleic acid binding protein
chr10_+_12728252 20.548 NM_175102
Sf3b5
splicing factor 3b, subunit 5
chr10_+_19928244 20.459 NM_001101561
Gm6251
predicted gene 6251
chr11_-_106117095 19.880 NM_025310
Ftsj3
FtsJ homolog 3 (E. coli)
chr12_-_81744771 19.714 NM_007951
Erh
enhancer of rudimentary homolog (Drosophila)
chr1_-_36758359 19.606 Actr1b
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr6_-_87793898 19.552 Cnbp
cellular nucleic acid binding protein
chrX_+_45499599 19.516 NM_028773
Sash3
SAM and SH3 domain containing 3
chr13_+_23844213 19.421 NM_178203
Hist1h3b
histone cluster 1, H3b
chrX_+_71032347 19.380 NM_001166480
Ssr4
signal sequence receptor, delta
chrX_+_71032398 18.390 Ssr4
signal sequence receptor, delta
chr19_+_39005433 18.358 NM_008234
Hells
helicase, lymphoid specific
chr4_+_118104028 18.217 Elovl1
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr5_+_144165615 18.166 Kdelr2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr7_+_86059105 18.047 NM_001113527
Isg20
interferon-stimulated protein
chr8_-_86781160 17.931 NM_026423
Mri1
methylthioribose-1-phosphate isomerase homolog (S. cerevisiae)
chr15_-_75901305 17.773 Puf60
poly-U binding splicing factor 60
chr9_+_108849655 17.730 Uqcrc1
ubiquinol-cytochrome c reductase core protein 1
chr8_+_108703001 17.282 Slc7a6
solute carrier family 7 (cationic amino acid transporter, y+ system), member 6
chr18_+_56867378 17.158 NM_010721
Lmnb1
lamin B1
chr10_+_79321979 17.147 Ptbp1
polypyrimidine tract binding protein 1
chr5_-_143666425 17.117


chr7_+_86059126 16.959 Isg20
interferon-stimulated protein
chr5_-_136387191 16.829 Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr10_-_111434265 16.729 NM_028608
Glipr1
GLI pathogenesis-related 1 (glioma)
chr11_+_29607599 16.670 Rtn4
reticulon 4
chr16_+_55966458 16.372 Rpl24
ribosomal protein L24
chr18_+_70728508 16.352 Mbd2
methyl-CpG binding domain protein 2
chr10_-_111434231 16.265 Glipr1
GLI pathogenesis-related 1 (glioma)
chr11_-_116711807 16.264 Srsf2
serine/arginine-rich splicing factor 2
chr2_+_32127324 16.259 NM_001195765
Gm13611
predicted gene 13611
chr13_+_74543843 16.156 Gm15590
ferritin light chain 1 pseudogene
chr5_-_136410216 15.829 Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr2_-_144096582 15.806 Snx5
sorting nexin 5
chr5_-_100407613 15.630 Hnrnpd
heterogeneous nuclear ribonucleoprotein D
chrX_-_43809499 15.553 NM_001085510
Gm4987
predicted gene 4987
chr12_+_52792192 15.323 Ap4s1
adaptor-related protein complex AP-4, sigma 1
chr14_-_67691221 15.306 NM_028032
Ppp2r2a
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform
chr11_-_106128935 15.116 NM_031878
Smarcd2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr9_-_75246118 15.008 Mapk6
mitogen-activated protein kinase 6
chr11_-_29501956 14.865


chr12_-_103213890 14.704 Gm2701
predicted gene 2701
chr18_+_70727897 14.703 NM_010773
Mbd2
methyl-CpG binding domain protein 2
chr2_-_179777080 14.639 NM_011969
Psma7
proteasome (prosome, macropain) subunit, alpha type 7
chr16_+_55966387 14.633 NM_024218
Rpl24
ribosomal protein L24
chr13_+_23625779 14.618 NM_175661
Hist1h2af
histone cluster 1, H2af
chr11_-_116714406 14.559 NM_011358
Srsf2
serine/arginine-rich splicing factor 2
chr9_+_120860017 14.181 Ctnnb1
catenin (cadherin associated protein), beta 1
chr15_+_58720783 14.162 NM_175226
Tatdn1
Rnf139
TatD DNase domain containing 1
ring finger protein 139
chr9_+_108849434 13.897 Uqcrc1
ubiquinol-cytochrome c reductase core protein 1
chr12_-_70683972 13.847 NM_001033236
Gm71
predicted gene 71
chrX_-_71481072 13.709 Flna
filamin, alpha
chr1_+_182499015 13.699 Parp1
poly (ADP-ribose) polymerase family, member 1
chr1_-_157883424 13.686 Tor1aip1
torsin A interacting protein 1
chr7_+_86058817 13.660 Isg20
interferon-stimulated protein
chr11_+_87861245 13.628 Srsf1
serine/arginine-rich splicing factor 1
chr2_-_132078887 13.618 NM_011045
Pcna
proliferating cell nuclear antigen
chr14_-_67690829 13.579 Ppp2r2a
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform
chr7_+_26472573 13.576 Tgfb1
transforming growth factor, beta 1
chr11_-_69730589 13.573 Eif5a
eukaryotic translation initiation factor 5A
chr11_-_120459646 13.494 NM_011568
Thoc4
THO complex 4
chr12_-_102321609 13.444 Smek1
SMEK homolog 1, suppressor of mek1 (Dictyostelium)
chr17_+_28344722 13.326 NM_027185
Def6
differentially expressed in FDCP 6
chr13_-_101556356 13.316 NM_172301
Ccnb1
cyclin B1
chr11_-_70465629 13.189 Pfn1
profilin 1
chr7_+_26472526 13.142 Tgfb1
transforming growth factor, beta 1
chr11_-_116713389 13.137 Srsf2
serine/arginine-rich splicing factor 2
chr8_-_72433344 13.095 Gatad2a
GATA zinc finger domain containing 2A
chr2_+_13496013 13.088 Vim
vimentin
chr13_+_23838602 13.030 NM_175664
Hist1h2bb
histone cluster 1, H2bb
chr7_-_17613079 13.029 NM_011155
Ppp5c
protein phosphatase 5, catalytic subunit
chr15_+_81977766 12.935 Srebf2
sterol regulatory element binding factor 2
chr12_+_73885063 12.857 Ppm1a
protein phosphatase 1A, magnesium dependent, alpha isoform
chr13_+_23627286 12.797 NM_145073
Hist1h3g
histone cluster 1, H3g
chr10_+_80642896 12.754 Eef2
eukaryotic translation elongation factor 2
chr11_-_17111582 12.688 NM_025443
Pno1
partner of NOB1 homolog (S. cerevisiae)
chr8_+_34763918 12.684 Gsr
glutathione reductase
chr11_-_17111513 12.622 Pno1
partner of NOB1 homolog (S. cerevisiae)
chr7_+_52973440 12.607 NM_009077
Rpl18
ribosomal protein L18
chr13_+_23663264 12.450 NM_178196
Hist1h2bg
histone cluster 1, H2bg
chr2_-_25078339 12.443


chr9_-_4309324 12.431 Aasdhppt
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr8_-_88063071 12.409


chr1_-_157882999 12.352 Tor1aip1
torsin A interacting protein 1
chr2_+_13495931 12.348 NM_011701
Vim
vimentin
chr2_+_13495963 12.311 Vim
vimentin
chr10_-_93052348 12.220 NM_027246
Snrpf
small nuclear ribonucleoprotein polypeptide F
chr5_-_143666064 12.219 Actb
actin, beta
chr1_+_182499091 12.172 NM_007415
Parp1
poly (ADP-ribose) polymerase family, member 1
chr12_-_29320801 12.018 NM_011300
Rps7
ribosomal protein S7
chr19_+_7049639 11.995 Ppp1r14b
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr4_-_100854453 11.972 Jak1
Janus kinase 1
chr5_-_144288771 11.962 Rac1
RAS-related C3 botulinum substrate 1
chr5_-_136386767 11.930 Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr3_-_143865162 11.878 NM_001161770
NM_001161769
Lmo4

LIM domain only 4

chr3_+_89883564 11.824 Tpm3
tropomyosin 3, gamma
chr13_-_22127419 11.799 NM_175659
Hist1h2ah
histone cluster 1, H2ah
chr14_-_62058627 11.794 NM_008466
Kpna3
karyopherin (importin) alpha 3
chr5_-_114221640 11.779 NM_016926
Sart3
squamous cell carcinoma antigen recognized by T-cells 3
chr11_-_69485800 11.768 Eif4a1
eukaryotic translation initiation factor 4A1
chr10_+_80639393 11.665 Eef2
eukaryotic translation elongation factor 2
chr10_+_80639371 11.528 NM_007907
Eef2
eukaryotic translation elongation factor 2
chrX_-_91368238 11.505 Zfx
zinc finger protein X-linked
chr13_-_23854226 11.455 NM_013550
Hist1h3a
histone cluster 1, H3a
chrX_-_100958883 11.422 NM_001170979
Gm6222
predicted pseudogene 6222
chr6_-_115758729 11.388 NM_172086
Rpl32
ribosomal protein L32
chr3_+_41367672 11.376 NM_001130185
Phf17
PHD finger protein 17
chr19_+_6298046 11.360 Ehd1
EH-domain containing 1
chr1_+_43245927 11.356 Rpl29
ribosomal protein L29
chr17_-_71201055 11.325 NM_001164075
Tgif1
TGFB-induced factor homeobox 1
chr4_-_118954780 11.206 Ybx1
Y box protein 1
chr10_-_20880559 11.199 NM_001198914
NM_010848
Myb

myeloblastosis oncogene

chr7_-_134852110 11.095 Bcl7c
B-cell CLL/lymphoma 7C
chrX_-_71470766 11.091 Flna
filamin, alpha
chr11_-_69485842 11.061 NM_001159375
NM_144958
Eif4a1

eukaryotic translation initiation factor 4A1

chr17_-_65929913 11.048


chr10_+_80639388 10.976 Eef2
eukaryotic translation elongation factor 2
chr10_+_127774845 10.920 Cs
citrate synthase
chr2_+_162758440 10.846 Srsf6
serine/arginine-rich splicing factor 6
chr3_+_32635988 10.829 Ndufb5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5
chr5_+_135663096 10.781 NM_011714
Baz1b
bromodomain adjacent to zinc finger domain, 1B
chr5_-_100392845 10.747 Hnrnpd
heterogeneous nuclear ribonucleoprotein D
chr15_+_76175485 10.716


chr18_+_64500017 10.653 NM_194268
Onecut2
one cut domain, family member 2
chr11_-_117687109 10.591 NM_009387
Tk1
thymidine kinase 1
chr19_+_5637459 10.584 NM_009045
Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr13_-_23775827 10.533 NM_178189
Hist1h2ac
histone cluster 1, H2ac
chr2_-_144096518 10.532 Snx5
sorting nexin 5
chr2_-_144096164 10.527 Snx5
sorting nexin 5
chr8_-_127386864 10.485 NM_025615
2810004N23Rik
RIKEN cDNA 2810004N23 gene
chr17_+_33961535 10.340 NM_023202
Ndufa7
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 (B14.5a)
chrX_-_71211653 10.337 NM_008224
Hcfc1
host cell factor C1
chr16_+_33056538 10.227 NM_001130485
NM_001130484
NM_021338
Rpl35a


ribosomal protein L35A


chr17_-_35972184 10.192 Tubb5
tubulin, beta 5
chr2_-_160192799 10.064 NM_010658
Mafb
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)
chr11_-_65601657 9.986 Map2k4
mitogen-activated protein kinase kinase 4
chr7_+_29595894 9.923 NM_177301
Hnrnpl
heterogeneous nuclear ribonucleoprotein L
chr16_+_94791713 9.906 NM_007890
Dyrk1a
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a
chr17_+_35400049 9.812 H2-D1
histocompatibility 2, D region locus 1
chr11_+_51781124 9.787 NM_029976
Cdkn2aipnl
CDKN2A interacting protein N-terminal like
chr14_-_69903072 9.723 NM_026331
Slc25a37
solute carrier family 25, member 37
chr7_-_121261292 9.709 NM_025846
Rras2
related RAS viral (r-ras) oncogene homolog 2
chr17_-_6132461 9.635 Gm15590
ferritin light chain 1 pseudogene
chr19_-_4305954 9.624 NM_130863
Adrbk1
adrenergic receptor kinase, beta 1
chr10_-_52265544 9.584 NM_009540
Zfa
zinc finger protein, autosomal
chr16_-_87486487 9.562 Cct8
chaperonin containing Tcp1, subunit 8 (theta)
chr8_-_87364463 9.553 NM_009010
Rad23a
RAD23a homolog (S. cerevisiae)
chr9_-_78326584 9.519 Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr17_-_71200462 9.471 NM_009372
Tgif1
TGFB-induced factor homeobox 1
chr4_-_109337891 9.444 NM_007671
Cdkn2c
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr19_+_9026020 9.431 Mta2
metastasis-associated gene family, member 2
chr7_+_25155415 9.403 Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr5_+_130535973 9.345


chr9_-_96379093 9.311 Rnf7
ring finger protein 7
chr7_-_4636141 9.289 Hspbp1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr11_+_48613820 9.222 NM_008143
Gnb2l1
guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1
chr10_+_127526038 9.209 Atp5b
ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
chr10_-_60915251 9.199 NM_010124
Eif4ebp2
eukaryotic translation initiation factor 4E binding protein 2
chr9_-_115219553 9.184 Stt3b
STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
chr9_-_115219177 9.162 Stt3b
STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
chr9_-_78326621 9.160 Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr6_+_91465970 9.147 Lsm3
LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr2_-_144096253 9.102 NM_024225
Snx5
sorting nexin 5
chr4_+_132753616 9.099


chr19_+_7049425 9.097 NM_008889
Ppp1r14b
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr5_-_137943329 9.097 Pop7
processing of precursor 7, ribonuclease P family, (S. cerevisiae)
chrX_+_93291377 9.074 NM_010833
Msn
moesin
chr14_+_25309968 9.045 Rps24
ribosomal protein S24
chr7_-_121261237 9.040 Rras2
related RAS viral (r-ras) oncogene homolog 2
chr11_-_115884712 9.012 H3f3b
H3 histone, family 3B
chr7_+_25155279 8.997 NM_001163510
NM_008433
Kcnn4

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4

chr1_+_4847774 8.950 NM_001159750
NM_011541
Tcea1

transcription elongation factor A (SII) 1

chr19_+_4231881 8.946 NM_027196
Pold4
polymerase (DNA-directed), delta 4
chr2_+_174170886 8.932 Gnas
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr3_+_89883461 8.921 Tpm3
tropomyosin 3, gamma
chr19_+_5637712 8.884 Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr8_+_34763709 8.879 NM_010344
Gsr
glutathione reductase
chr10_+_79317409 8.861 Ptbp1
polypyrimidine tract binding protein 1
chr9_-_108469672 8.859 NM_023247
Ndufaf3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr2_-_160192500 8.837 Mafb
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)
chr18_+_61847568 8.834 NM_019508
Il17b
interleukin 17B
chr5_-_116252183 8.814 Rpl29
ribosomal protein L29

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.52 3.18e-154 GO:0044237 cellular metabolic process
1.61 1.55e-133 GO:0044260 cellular macromolecule metabolic process
1.42 1.45e-125 GO:0008152 metabolic process
1.46 5.75e-123 GO:0044238 primary metabolic process
1.53 1.84e-117 GO:0043170 macromolecule metabolic process
1.76 3.93e-97 GO:0010467 gene expression
1.62 1.19e-84 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.58 3.34e-84 GO:0034641 cellular nitrogen compound metabolic process
1.56 9.69e-83 GO:0006807 nitrogen compound metabolic process
1.66 1.74e-78 GO:0090304 nucleic acid metabolic process
1.60 3.79e-76 GO:0044249 cellular biosynthetic process
1.68 1.52e-73 GO:0034645 cellular macromolecule biosynthetic process
1.68 3.35e-73 GO:0009059 macromolecule biosynthetic process
1.58 5.06e-73 GO:0009058 biosynthetic process
1.69 2.79e-72 GO:0016070 RNA metabolic process
1.18 5.69e-61 GO:0009987 cellular process
1.65 7.30e-60 GO:0044267 cellular protein metabolic process
1.46 1.87e-53 GO:0031323 regulation of cellular metabolic process
1.46 4.92e-52 GO:0060255 regulation of macromolecule metabolic process
1.45 2.06e-51 GO:0080090 regulation of primary metabolic process
1.41 5.09e-51 GO:0019222 regulation of metabolic process
1.51 8.11e-47 GO:0019538 protein metabolic process
1.51 1.70e-46 GO:0010468 regulation of gene expression
1.51 2.47e-44 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.50 2.15e-42 GO:0010556 regulation of macromolecule biosynthetic process
1.51 6.91e-41 GO:0051252 regulation of RNA metabolic process
1.47 7.67e-40 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.60 7.67e-39 GO:0032774 RNA biosynthetic process
1.60 8.18e-39 GO:0006351 transcription, DNA-dependent
1.46 1.57e-38 GO:0051171 regulation of nitrogen compound metabolic process
1.50 2.28e-37 GO:0006355 regulation of transcription, DNA-dependent
1.45 3.81e-37 GO:0031326 regulation of cellular biosynthetic process
2.55 5.14e-37 GO:0006412 translation
1.44 1.72e-36 GO:0009889 regulation of biosynthetic process
2.06 1.68e-33 GO:0006396 RNA processing
1.40 5.89e-32 GO:0071840 cellular component organization or biogenesis
1.44 1.75e-28 GO:0071841 cellular component organization or biogenesis at cellular level
1.57 3.24e-28 GO:0006996 organelle organization
1.37 2.07e-25 GO:0016043 cellular component organization
3.28 1.81e-24 GO:0006414 translational elongation
2.24 1.04e-22 GO:0008380 RNA splicing
2.05 3.72e-21 GO:0016071 mRNA metabolic process
1.40 4.66e-21 GO:0071842 cellular component organization at cellular level
1.67 1.20e-20 GO:0007049 cell cycle
1.51 2.97e-20 GO:0010604 positive regulation of macromolecule metabolic process
1.99 3.32e-20 GO:0006325 chromatin organization
1.44 3.66e-20 GO:0043412 macromolecule modification
1.60 3.89e-20 GO:0010605 negative regulation of macromolecule metabolic process
1.45 4.59e-20 GO:0006464 protein modification process
1.36 4.91e-20 GO:0048519 negative regulation of biological process
1.38 7.69e-20 GO:0048523 negative regulation of cellular process
1.35 3.16e-19 GO:0048522 positive regulation of cellular process
1.83 3.42e-19 GO:0051276 chromosome organization
2.04 4.04e-19 GO:0016568 chromatin modification
1.32 4.35e-19 GO:0048518 positive regulation of biological process
1.56 4.72e-19 GO:0009892 negative regulation of metabolic process
1.52 5.73e-19 GO:0033036 macromolecule localization
1.95 9.52e-19 GO:0000278 mitotic cell cycle
1.64 2.46e-18 GO:0045184 establishment of protein localization
1.64 4.09e-18 GO:0015031 protein transport
1.57 4.65e-18 GO:0031324 negative regulation of cellular metabolic process
1.48 7.35e-18 GO:0031325 positive regulation of cellular metabolic process
1.46 1.18e-17 GO:0009893 positive regulation of metabolic process
1.55 2.74e-17 GO:0008104 protein localization
1.55 3.49e-17 GO:0044085 cellular component biogenesis
2.06 3.71e-17 GO:0006397 mRNA processing
2.06 6.36e-17 GO:0043632 modification-dependent macromolecule catabolic process
2.06 8.76e-17 GO:0019941 modification-dependent protein catabolic process
2.05 7.30e-16 GO:0006511 ubiquitin-dependent protein catabolic process
1.83 1.04e-15 GO:0044265 cellular macromolecule catabolic process
2.01 1.14e-15 GO:0051603 proteolysis involved in cellular protein catabolic process
1.53 1.47e-15 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.68 2.20e-15 GO:0046907 intracellular transport
1.99 2.70e-15 GO:0044257 cellular protein catabolic process
1.94 6.00e-15 GO:0030163 protein catabolic process
2.21 6.19e-15 GO:0071843 cellular component biogenesis at cellular level
2.24 7.92e-15 GO:0022613 ribonucleoprotein complex biogenesis
1.67 4.03e-14 GO:0022402 cell cycle process
1.72 7.28e-14 GO:0009057 macromolecule catabolic process
1.48 1.29e-13 GO:0044248 cellular catabolic process
1.54 1.55e-13 GO:0010628 positive regulation of gene expression
1.56 3.50e-13 GO:0045893 positive regulation of transcription, DNA-dependent
1.50 3.62e-13 GO:0032268 regulation of cellular protein metabolic process
1.56 4.45e-13 GO:0051254 positive regulation of RNA metabolic process
1.51 5.54e-13 GO:0010557 positive regulation of macromolecule biosynthetic process
2.41 5.61e-13 GO:0042254 ribosome biogenesis
1.42 1.22e-12 GO:0009056 catabolic process
1.51 1.34e-12 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.70 4.41e-12 GO:0051726 regulation of cell cycle
1.49 5.44e-12 GO:0051173 positive regulation of nitrogen compound metabolic process
1.89 1.07e-11 GO:0018193 peptidyl-amino acid modification
1.45 1.81e-11 GO:0051641 cellular localization
1.46 5.62e-11 GO:0031328 positive regulation of cellular biosynthetic process
2.23 5.72e-11 GO:0010498 proteasomal protein catabolic process
2.23 5.72e-11 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
1.43 6.20e-11 GO:0051246 regulation of protein metabolic process
2.05 1.85e-10 GO:0016570 histone modification
2.04 2.03e-10 GO:0016569 covalent chromatin modification
1.44 3.51e-10 GO:0009891 positive regulation of biosynthetic process
1.25 5.07e-10 GO:0051234 establishment of localization
1.22 5.56e-10 GO:0051179 localization
2.70 1.22e-09 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
2.02 1.50e-09 GO:0034470 ncRNA processing
1.42 1.67e-09 GO:0010941 regulation of cell death
1.90 1.79e-09 GO:0034660 ncRNA metabolic process
1.24 1.90e-09 GO:0006810 transport
1.46 1.93e-09 GO:0051649 establishment of localization in cell
1.56 3.19e-09 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.65 3.27e-09 GO:0022403 cell cycle phase
2.70 4.16e-09 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.41 4.24e-09 GO:0043067 regulation of programmed cell death
1.83 4.28e-09 GO:0051248 negative regulation of protein metabolic process
2.11 4.83e-09 GO:0031396 regulation of protein ubiquitination
1.48 5.05e-09 GO:0031327 negative regulation of cellular biosynthetic process
1.49 5.58e-09 GO:0010558 negative regulation of macromolecule biosynthetic process
1.84 5.62e-09 GO:0032269 negative regulation of cellular protein metabolic process
1.41 6.52e-09 GO:0042981 regulation of apoptosis
1.47 9.23e-09 GO:0009890 negative regulation of biosynthetic process
1.49 9.92e-09 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.52 1.05e-08 GO:0051443 positive regulation of ubiquitin-protein ligase activity
1.44 1.36e-08 GO:0022607 cellular component assembly
2.61 1.49e-08 GO:0051352 negative regulation of ligase activity
2.61 1.49e-08 GO:0051444 negative regulation of ubiquitin-protein ligase activity
2.43 1.65e-08 GO:0031397 negative regulation of protein ubiquitination
1.53 1.92e-08 GO:0065003 macromolecular complex assembly
1.60 1.99e-08 GO:0070727 cellular macromolecule localization
1.31 2.15e-08 GO:0044281 small molecule metabolic process
2.32 2.17e-08 GO:0018205 peptidyl-lysine modification
2.40 2.27e-08 GO:0051438 regulation of ubiquitin-protein ligase activity
1.51 2.57e-08 GO:0043933 macromolecular complex subunit organization
2.24 3.14e-08 GO:0031398 positive regulation of protein ubiquitination
1.46 3.78e-08 GO:0031399 regulation of protein modification process
2.46 3.87e-08 GO:0051351 positive regulation of ligase activity
1.59 4.25e-08 GO:0034613 cellular protein localization
1.69 4.29e-08 GO:0051301 cell division
1.49 4.36e-08 GO:0033554 cellular response to stress
1.69 5.88e-08 GO:0006886 intracellular protein transport
2.34 7.25e-08 GO:0051340 regulation of ligase activity
1.48 7.62e-08 GO:0010629 negative regulation of gene expression
2.55 7.87e-08 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.47 8.48e-08 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.49 8.95e-08 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.46 1.47e-07 GO:0051172 negative regulation of nitrogen compound metabolic process
1.55 1.84e-07 GO:0006259 DNA metabolic process
1.96 2.50e-07 GO:0031400 negative regulation of protein modification process
1.48 3.68e-07 GO:0051253 negative regulation of RNA metabolic process
1.60 4.01e-07 GO:0006974 response to DNA damage stimulus
1.37 7.50e-07 GO:0006796 phosphate metabolic process
1.36 9.78e-07 GO:0006793 phosphorus metabolic process
1.57 1.02e-06 GO:0051247 positive regulation of protein metabolic process
1.29 1.18e-06 GO:0065009 regulation of molecular function
1.58 1.40e-06 GO:0032270 positive regulation of cellular protein metabolic process
1.71 1.42e-06 GO:0034622 cellular macromolecular complex assembly
1.46 1.60e-06 GO:0012501 programmed cell death
1.46 2.46e-06 GO:0006915 apoptosis
1.78 3.39e-06 GO:0051186 cofactor metabolic process
2.31 4.37e-06 GO:0006403 RNA localization
2.21 4.44e-06 GO:0006364 rRNA processing
1.45 4.45e-06 GO:0045892 negative regulation of transcription, DNA-dependent
1.75 5.85e-06 GO:0006091 generation of precursor metabolites and energy
1.32 5.98e-06 GO:0050790 regulation of catalytic activity
1.42 7.38e-06 GO:0016265 death
1.63 7.60e-06 GO:0034621 cellular macromolecular complex subunit organization
1.71 8.92e-06 GO:0010608 posttranscriptional regulation of gene expression
1.46 1.04e-05 GO:0071844 cellular component assembly at cellular level
1.75 1.09e-05 GO:0010564 regulation of cell cycle process
1.49 1.34e-05 GO:0043009 chordate embryonic development
2.30 1.39e-05 GO:0050657 nucleic acid transport
2.30 1.39e-05 GO:0050658 RNA transport
2.30 1.39e-05 GO:0051236 establishment of RNA localization
1.94 1.51e-05 GO:0006913 nucleocytoplasmic transport
1.82 1.54e-05 GO:0007346 regulation of mitotic cell cycle
1.43 1.61e-05 GO:0046483 heterocycle metabolic process
1.73 1.83e-05 GO:0000087 M phase of mitotic cell cycle
2.14 1.87e-05 GO:0016072 rRNA metabolic process
2.08 1.98e-05 GO:0022900 electron transport chain
1.41 2.05e-05 GO:0008219 cell death
1.71 2.35e-05 GO:0048285 organelle fission
1.73 2.50e-05 GO:0000280 nuclear division
1.73 2.50e-05 GO:0007067 mitosis
1.17 2.66e-05 GO:0032502 developmental process
1.87 3.51e-05 GO:0006260 DNA replication
1.19 4.24e-05 GO:0048856 anatomical structure development
1.90 4.41e-05 GO:0051169 nuclear transport
1.58 4.44e-05 GO:0031401 positive regulation of protein modification process
1.47 4.52e-05 GO:0009792 embryo development ending in birth or egg hatching
1.60 5.08e-05 GO:0070647 protein modification by small protein conjugation or removal
2.13 7.67e-05 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
2.06 7.90e-05 GO:0071156 regulation of cell cycle arrest
1.36 1.34e-04 GO:0045595 regulation of cell differentiation
2.00 1.41e-04 GO:0071103 DNA conformation change
1.47 1.67e-04 GO:0043066 negative regulation of apoptosis
2.27 1.90e-04 GO:0051028 mRNA transport
1.45 2.07e-04 GO:0060548 negative regulation of cell death
2.23 2.32e-04 GO:0018394 peptidyl-lysine acetylation
1.43 2.40e-04 GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
2.08 2.56e-04 GO:0000075 cell cycle checkpoint
1.46 2.60e-04 GO:0043069 negative regulation of programmed cell death
1.54 3.10e-04 GO:0000279 M phase
2.16 3.27e-04 GO:0006473 protein acetylation
3.05 3.35e-04 GO:0043488 regulation of mRNA stability
1.58 3.79e-04 GO:0006281 DNA repair
2.06 3.91e-04 GO:0043543 protein acylation
1.76 4.25e-04 GO:0006605 protein targeting
2.20 5.24e-04 GO:0006475 internal protein amino acid acetylation
2.20 5.24e-04 GO:0018393 internal peptidyl-lysine acetylation
1.35 6.30e-04 GO:0006508 proteolysis
1.47 7.11e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.21 7.20e-04 GO:0016573 histone acetylation
1.33 7.45e-04 GO:0009790 embryo development
1.93 8.75e-04 GO:0048193 Golgi vesicle transport
1.55 9.05e-04 GO:0009259 ribonucleotide metabolic process
1.98 1.02e-03 GO:0051329 interphase of mitotic cell cycle
1.55 1.07e-03 GO:0009150 purine ribonucleotide metabolic process
1.96 1.09e-03 GO:0051325 interphase
1.32 1.44e-03 GO:0016310 phosphorylation
1.16 1.46e-03 GO:0007275 multicellular organismal development
1.81 1.47e-03 GO:0006417 regulation of translation
1.28 1.49e-03 GO:0050793 regulation of developmental process
2.18 1.61e-03 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.18 1.61e-03 GO:0000398 nuclear mRNA splicing, via spliceosome
1.42 1.65e-03 GO:0006753 nucleoside phosphate metabolic process
1.42 1.65e-03 GO:0009117 nucleotide metabolic process
1.72 1.74e-03 GO:0006732 coenzyme metabolic process
1.18 1.89e-03 GO:0048731 system development
2.15 2.58e-03 GO:0000375 RNA splicing, via transesterification reactions
1.64 5.10e-03 GO:0033365 protein localization to organelle
2.74 5.18e-03 GO:0043487 regulation of RNA stability
1.19 5.58e-03 GO:0048869 cellular developmental process
1.20 5.99e-03 GO:0048513 organ development
1.55 6.34e-03 GO:0061061 muscle structure development
1.34 6.92e-03 GO:0019220 regulation of phosphate metabolic process
1.34 6.92e-03 GO:0051174 regulation of phosphorus metabolic process
1.39 7.28e-03 GO:0010942 positive regulation of cell death
1.31 7.33e-03 GO:0044093 positive regulation of molecular function
1.54 7.33e-03 GO:0032446 protein modification by small protein conjugation
3.77 7.58e-03 GO:0016180 snRNA processing
1.19 7.85e-03 GO:0030154 cell differentiation
1.72 8.22e-03 GO:0006457 protein folding
1.82 9.04e-03 GO:0006470 protein dephosphorylation
2.31 9.93e-03 GO:0006338 chromatin remodeling
1.38 1.10e-02 GO:0043068 positive regulation of programmed cell death
1.44 1.15e-02 GO:0044262 cellular carbohydrate metabolic process
3.09 1.21e-02 GO:0043489 RNA stabilization
3.09 1.21e-02 GO:0048255 mRNA stabilization
1.51 1.26e-02 GO:0009144 purine nucleoside triphosphate metabolic process
2.06 1.34e-02 GO:0002755 MyD88-dependent toll-like receptor signaling pathway
1.94 1.38e-02 GO:0006323 DNA packaging
1.40 1.49e-02 GO:0070271 protein complex biogenesis
1.50 1.61e-02 GO:0009141 nucleoside triphosphate metabolic process
2.27 1.70e-02 GO:0007093 mitotic cell cycle checkpoint
1.43 1.78e-02 GO:0010627 regulation of intracellular protein kinase cascade
1.40 1.85e-02 GO:0006461 protein complex assembly
1.55 2.02e-02 GO:0043193 positive regulation of gene-specific transcription
1.62 2.12e-02 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
1.81 2.27e-02 GO:0015980 energy derivation by oxidation of organic compounds
1.43 2.42e-02 GO:0006163 purine nucleotide metabolic process
1.41 2.50e-02 GO:0072521 purine-containing compound metabolic process
1.50 2.63e-02 GO:0009205 purine ribonucleoside triphosphate metabolic process
1.37 2.66e-02 GO:0043065 positive regulation of apoptosis
1.90 2.82e-02 GO:0009260 ribonucleotide biosynthetic process
1.33 2.94e-02 GO:0016192 vesicle-mediated transport
1.56 3.08e-02 GO:0018130 heterocycle biosynthetic process
1.49 3.78e-02 GO:0009199 ribonucleoside triphosphate metabolic process
1.51 3.79e-02 GO:0072523 purine-containing compound catabolic process
1.44 4.39e-02 GO:0044271 cellular nitrogen compound biosynthetic process
1.37 4.59e-02 GO:0071822 protein complex subunit organization
2.06 4.89e-02 GO:0045333 cellular respiration

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.40 2.87e-238 GO:0044424 intracellular part
1.39 1.11e-235 GO:0005622 intracellular
1.44 5.83e-207 GO:0043229 intracellular organelle
1.44 5.55e-206 GO:0043226 organelle
1.48 7.92e-199 GO:0043227 membrane-bounded organelle
1.48 1.93e-198 GO:0043231 intracellular membrane-bounded organelle
1.59 1.14e-140 GO:0005634 nucleus
1.39 2.59e-128 GO:0005737 cytoplasm
1.62 2.57e-121 GO:0044422 organelle part
1.63 4.37e-121 GO:0044446 intracellular organelle part
1.67 1.70e-105 GO:0032991 macromolecular complex
1.45 1.71e-93 GO:0044444 cytoplasmic part
1.94 9.74e-93 GO:0070013 intracellular organelle lumen
1.94 9.97e-93 GO:0043233 organelle lumen
1.93 1.24e-92 GO:0031974 membrane-enclosed lumen
1.91 3.40e-92 GO:0044428 nuclear part
1.15 2.06e-82 GO:0005623 cell
1.15 2.06e-82 GO:0044464 cell part
1.93 2.78e-77 GO:0031981 nuclear lumen
1.57 5.68e-63 GO:0043234 protein complex
2.00 3.07e-60 GO:0005654 nucleoplasm
2.39 3.14e-52 GO:0030529 ribonucleoprotein complex
1.56 5.86e-51 GO:0043228 non-membrane-bounded organelle
1.56 5.86e-51 GO:0043232 intracellular non-membrane-bounded organelle
1.71 2.54e-47 GO:0005829 cytosol
2.97 1.31e-36 GO:0005840 ribosome
1.95 3.97e-36 GO:0044451 nucleoplasm part
1.61 9.42e-35 GO:0005739 mitochondrion
1.91 9.61e-27 GO:0044429 mitochondrial part
1.78 3.40e-22 GO:0031967 organelle envelope
1.76 7.97e-22 GO:0031975 envelope
1.91 8.33e-18 GO:0005730 nucleolus
1.82 1.35e-17 GO:0005694 chromosome
1.46 6.99e-16 GO:0031090 organelle membrane
2.37 1.02e-15 GO:0005759 mitochondrial matrix
1.90 1.25e-15 GO:0019866 organelle inner membrane
1.79 1.79e-15 GO:0005740 mitochondrial envelope
1.80 1.83e-15 GO:0031966 mitochondrial membrane
2.55 3.94e-15 GO:0044445 cytosolic part
1.91 3.95e-15 GO:0005743 mitochondrial inner membrane
1.78 1.49e-14 GO:0044427 chromosomal part
3.31 3.49e-14 GO:0015935 small ribosomal subunit
2.33 6.42e-13 GO:0005681 spliceosomal complex
3.15 4.46e-11 GO:0022626 cytosolic ribosome
2.72 9.01e-09 GO:0000502 proteasome complex
2.28 9.58e-09 GO:0044455 mitochondrial membrane part
2.77 1.37e-08 GO:0070469 respiratory chain
1.70 2.33e-08 GO:0005667 transcription factor complex
2.89 2.80e-08 GO:0005746 mitochondrial respiratory chain
2.42 3.54e-08 GO:0071013 catalytic step 2 spliceosome
2.04 5.73e-08 GO:0016604 nuclear body
2.39 6.44e-08 GO:0016585 chromatin remodeling complex
2.94 1.10e-07 GO:0000313 organellar ribosome
2.94 1.10e-07 GO:0005761 mitochondrial ribosome
1.82 1.11e-07 GO:0000785 chromatin
1.29 2.34e-07 GO:0005856 cytoskeleton
1.81 2.78e-07 GO:0000228 nuclear chromosome
2.97 1.28e-06 GO:0005747 mitochondrial respiratory chain complex I
2.97 1.28e-06 GO:0030964 NADH dehydrogenase complex
2.97 1.28e-06 GO:0045271 respiratory chain complex I
3.03 1.42e-06 GO:0022627 cytosolic small ribosomal subunit
1.57 2.86e-06 GO:0005625 soluble fraction
4.11 7.12e-06 GO:0000314 organellar small ribosomal subunit
4.11 7.12e-06 GO:0005763 mitochondrial small ribosomal subunit
2.38 7.28e-06 GO:0000123 histone acetyltransferase complex
2.82 2.77e-05 GO:0015934 large ribosomal subunit
1.75 3.36e-05 GO:0044454 nuclear chromosome part
1.73 5.76e-05 GO:0005635 nuclear envelope
1.86 6.13e-05 GO:0000775 chromosome, centromeric region
2.30 1.34e-04 GO:0034708 methyltransferase complex
2.30 1.34e-04 GO:0035097 histone methyltransferase complex
1.33 1.36e-04 GO:0012505 endomembrane system
1.39 1.49e-04 GO:0015630 microtubule cytoskeleton
2.22 2.77e-04 GO:0000792 heterochromatin
1.28 4.82e-04 GO:0005794 Golgi apparatus
1.27 6.10e-04 GO:0005783 endoplasmic reticulum
2.19 8.58e-04 GO:0034399 nuclear periphery
2.49 1.50e-03 GO:0000118 histone deacetylase complex
2.33 2.02e-03 GO:0017053 transcriptional repressor complex
1.27 2.21e-03 GO:0044430 cytoskeletal part
1.87 3.23e-03 GO:0000790 nuclear chromatin
3.74 4.27e-03 GO:0032039 integrator complex
3.03 5.59e-03 GO:0031519 PcG protein complex
3.48 5.71e-03 GO:0005852 eukaryotic translation initiation factor 3 complex
1.37 8.97e-03 GO:0005768 endosome
2.18 9.55e-03 GO:0016363 nuclear matrix
2.44 1.71e-02 GO:0008287 protein serine/threonine phosphatase complex
2.44 1.71e-02 GO:0042645 mitochondrial nucleoid
3.09 1.94e-02 GO:0043596 nuclear replication fork
2.02 2.11e-02 GO:0046930 pore complex
1.21 2.70e-02 GO:0000267 cell fraction
1.52 2.74e-02 GO:0005813 centrosome
1.82 2.90e-02 GO:0000776 kinetochore
2.37 3.11e-02 GO:0009295 nucleoid
2.02 4.04e-02 GO:0016607 nuclear speck
2.82 4.21e-02 GO:0005839 proteasome core complex

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.23 1.25e-74 GO:0005488 binding
1.54 1.39e-51 GO:0003676 nucleic acid binding
1.32 1.71e-48 GO:0005515 protein binding
2.04 8.47e-45 GO:0003723 RNA binding
1.53 5.00e-40 GO:0000166 nucleotide binding
3.20 5.46e-31 GO:0003735 structural constituent of ribosome
1.27 9.37e-30 GO:0003824 catalytic activity
1.45 6.64e-23 GO:0035639 purine ribonucleoside triphosphate binding
1.44 1.11e-22 GO:0017076 purine nucleotide binding
1.44 1.95e-22 GO:0032555 purine ribonucleotide binding
1.44 2.31e-22 GO:0032553 ribonucleotide binding
1.43 4.91e-21 GO:0003677 DNA binding
1.44 2.31e-17 GO:0005524 ATP binding
1.43 2.70e-17 GO:0030554 adenyl nucleotide binding
1.43 4.65e-17 GO:0032559 adenyl ribonucleotide binding
1.52 1.53e-14 GO:0030528 transcription regulator activity
1.76 1.00e-12 GO:0005198 structural molecule activity
1.49 5.80e-12 GO:0019899 enzyme binding
1.93 3.62e-11 GO:0000989 transcription factor binding transcription factor activity
1.92 7.08e-11 GO:0003712 transcription cofactor activity
1.90 1.05e-10 GO:0000988 protein binding transcription factor activity
1.30 1.30e-09 GO:0016740 transferase activity
1.84 1.43e-07 GO:0003682 chromatin binding
1.23 2.31e-07 GO:0016787 hydrolase activity
1.65 5.55e-07 GO:0008134 transcription factor binding
1.36 9.20e-07 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.40 5.00e-06 GO:0046983 protein dimerization activity
1.43 6.09e-06 GO:0017111 nucleoside-triphosphatase activity
1.41 8.80e-06 GO:0016462 pyrophosphatase activity
1.40 1.37e-05 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
2.12 1.51e-05 GO:0008135 translation factor activity, nucleic acid binding
1.40 1.58e-05 GO:0016817 hydrolase activity, acting on acid anhydrides
2.29 1.62e-05 GO:0008565 protein transporter activity
1.36 1.71e-05 GO:0042802 identical protein binding
2.15 1.80e-05 GO:0003729 mRNA binding
1.59 2.46e-05 GO:0019900 kinase binding
1.64 4.03e-05 GO:0019901 protein kinase binding
1.36 4.17e-05 GO:0001071 nucleic acid binding transcription factor activity
1.36 4.17e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.56 4.93e-05 GO:0016564 transcription repressor activity
1.25 1.35e-04 GO:0008270 zinc ion binding
1.48 1.76e-04 GO:0016874 ligase activity
2.08 1.81e-04 GO:0051082 unfolded protein binding
1.36 4.00e-04 GO:0043565 sequence-specific DNA binding
1.99 4.91e-04 GO:0003714 transcription corepressor activity
1.75 5.16e-04 GO:0004721 phosphoprotein phosphatase activity
1.22 5.76e-04 GO:0046914 transition metal ion binding
1.62 7.79e-04 GO:0042623 ATPase activity, coupled
2.23 9.47e-04 GO:0003743 translation initiation factor activity
3.25 1.05e-03 GO:0003954 NADH dehydrogenase activity
1.48 1.27e-03 GO:0016563 transcription activator activity
1.76 1.31e-03 GO:0003713 transcription coactivator activity
1.59 1.81e-03 GO:0016881 acid-amino acid ligase activity
1.37 2.77e-03 GO:0019904 protein domain specific binding
1.30 2.91e-03 GO:0016301 kinase activity
1.32 2.98e-03 GO:0016788 hydrolase activity, acting on ester bonds
1.51 3.02e-03 GO:0046982 protein heterodimerization activity
1.32 3.19e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
3.09 3.26e-03 GO:0016655 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
1.52 3.36e-03 GO:0016887 ATPase activity
3.20 3.45e-03 GO:0008137 NADH dehydrogenase (ubiquinone) activity
3.20 3.45e-03 GO:0050136 NADH dehydrogenase (quinone) activity
1.61 3.48e-03 GO:0019787 small conjugating protein ligase activity
1.13 3.75e-03 GO:0043169 cation binding
1.13 3.98e-03 GO:0046872 metal ion binding
1.46 4.04e-03 GO:0005525 GTP binding
1.13 4.66e-03 GO:0043167 ion binding
1.44 5.97e-03 GO:0019001 guanyl nucleotide binding
1.44 5.97e-03 GO:0032561 guanyl ribonucleotide binding
1.43 7.17e-03 GO:0032403 protein complex binding
2.22 7.68e-03 GO:0043021 ribonucleoprotein binding
1.51 7.99e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
2.69 1.36e-02 GO:0019843 rRNA binding
1.90 2.62e-02 GO:0008026 ATP-dependent helicase activity
1.90 2.62e-02 GO:0070035 purine NTP-dependent helicase activity
2.14 2.78e-02 GO:0016651 oxidoreductase activity, acting on NADH or NADPH
1.60 3.07e-02 GO:0008022 protein C-terminus binding
1.37 3.43e-02 GO:0004674 protein serine/threonine kinase activity
1.53 4.10e-02 GO:0043566 structure-specific DNA binding
2.35 4.13e-02 GO:0042054 histone methyltransferase activity
1.48 4.14e-02 GO:0016791 phosphatase activity
1.55 4.47e-02 GO:0004842 ubiquitin-protein ligase activity
2.68 4.78e-02 GO:0004402 histone acetyltransferase activity
2.68 4.78e-02 GO:0004468 lysine N-acetyltransferase activity
2.68 4.78e-02 GO:0016455 RNA polymerase II transcription mediator activity