Motif ID: ZBTB16.p2

Z-value: 1.221


Transcription factors associated with ZBTB16.p2:

Gene SymbolEntrez IDGene Name
Zbtb16 235320 zinc finger and BTB domain containing 16

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb16chr9_-_48644030-0.444.3e-10Click!


Activity profile for motif ZBTB16.p2.

activity profile for motif ZBTB16.p2


Sorted Z-values histogram for motif ZBTB16.p2

Sorted Z-values for motif ZBTB16.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB16.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_115373246 27.392 NM_145209
Oasl1
2'-5' oligoadenylate synthetase-like 1
chr5_+_115373272 23.061 Oasl1
2'-5' oligoadenylate synthetase-like 1
chr4_+_44313865 19.964 Melk
maternal embryonic leucine zipper kinase
chr11_+_82988687 19.282 NM_011410
Slfn4
schlafen 4
chr4_+_44313764 18.613 NM_010790
Melk
maternal embryonic leucine zipper kinase
chr10_-_61960613 16.326 Srgn
serglycin
chr2_-_129094163 14.151 Ckap2l
cytoskeleton associated protein 2-like
chr1_+_109407998 13.631 NM_001174170
NM_011111
Serpinb2

serine (or cysteine) peptidase inhibitor, clade B, member 2

chr11_+_81859212 12.696 NM_013654
Ccl7
chemokine (C-C motif) ligand 7
chr11_+_68859125 12.281 NM_011496
Aurkb
aurora kinase B
chr1_-_175805812 11.992 Mndal
myeloid nuclear differentiation antigen like
chr8_-_124948837 11.969


chr19_+_29441927 11.882 NM_021893
Cd274
CD274 antigen
chr1_-_158585297 11.642 Tor3a
torsin family 3, member A
chr11_-_83388330 11.615 Ccl9
chemokine (C-C motif) ligand 9
chr19_+_11518042 11.352 NM_021718
Ms4a4b
membrane-spanning 4-domains, subfamily A, member 4B
chr12_+_82049290 11.206 Srsf5
serine/arginine-rich splicing factor 5
chr11_-_98862163 10.940 Top2a
topoisomerase (DNA) II alpha
chr15_+_103284200 10.793 NM_153505
Nckap1l
NCK associated protein 1 like
chr1_+_173612132 9.845 Cd48
CD48 antigen
chr5_+_115373333 9.789 Oasl1
2'-5' oligoadenylate synthetase-like 1
chr17_-_32557807 9.712 Pglyrp2
peptidoglycan recognition protein 2
chr1_+_173612173 9.664 NM_007649
Cd48
CD48 antigen
chr10_-_88875526 9.550 Gas2l3
growth arrest-specific 2 like 3
chr16_+_44811858 9.360 Cd200r4
CD200 receptor 4
chr10_+_126503214 9.221 Cdk4
cyclin-dependent kinase 4
chr7_+_4225744 9.168 NM_011093
NM_008848
Pira6

paired-Ig-like receptor A6

chr17_-_32557916 8.995 NM_021319
Pglyrp2
peptidoglycan recognition protein 2
chr15_+_102289600 8.959 NM_001170911
NM_025385
Prr13

proline rich 13

chr16_-_36666078 8.559 NM_019388
Cd86
CD86 antigen
chr16_-_75909440 8.444 NM_023380
Samsn1
SAM domain, SH3 domain and nuclear localization signals, 1
chr7_+_29222465 8.442 NM_022024
Gmfg
glia maturation factor, gamma
chr6_+_137703029 8.199 NM_172733
Dera
2-deoxyribose-5-phosphate aldolase homolog (C. elegans)
chr5_+_34014563 8.192


chr14_-_122364309 8.168 NM_183031
Gpr183
G protein-coupled receptor 183
chr6_-_131197295 8.151 NM_001170851
NM_008462
Klra2

killer cell lectin-like receptor, subfamily A, member 2

chr5_+_86500770 8.091 NM_019992
Stap1
signal transducing adaptor family member 1
chr13_+_52678805 8.029 NM_001198977
Sykb
spleen tyrosine kinase
chr2_+_129442079 7.867 Sirpa
signal-regulatory protein alpha
chr6_-_3295980 7.859 9530028C05
hypothetical protein 9530028C05
chr8_+_74662546 7.813 Tpm4
tropomyosin 4
chr6_-_129572590 7.766 NM_033078
Klrk1
killer cell lectin-like receptor subfamily K, member 1
chr1_-_146096156 7.763 NM_015811
Rgs1
regulator of G-protein signaling 1
chr2_-_60589059 7.749 Rbms1
RNA binding motif, single stranded interacting protein 1
chr5_-_134705423 7.733 NM_010876
Ncf1
neutrophil cytosolic factor 1
chr4_+_128688217 7.481


chr8_-_4779533 7.258 NM_011369
Shcbp1
Shc SH2-domain binding protein 1
chr2_+_150735306 7.183 NM_001163476
NM_027014
Gins1

GINS complex subunit 1 (Psf1 homolog)

chr11_+_83037063 7.065 AI662270
expressed sequence AI662270
chrX_+_156278399 6.950 NM_001135728
Sh3kbp1
SH3-domain kinase binding protein 1
chr14_+_51748742 6.918 NM_030098
Rnase6
ribonuclease, RNase A family, 6
chr7_-_25873560 6.841


chr2_-_169956719 6.813 NM_001033299
Zfp217
zinc finger protein 217
chr16_-_4679664 6.782 NM_030205
Coro7
coronin 7
chr4_+_134676559 6.670 NM_019732
Runx3
runt related transcription factor 3
chr4_-_120597563 6.601 NM_001160043
NM_028457
Dem1

defects in morphology 1 homolog (S. cerevisiae)

chr3_+_90407688 6.549 NM_011311
S100a4
S100 calcium binding protein A4
chr11_-_69709003 6.471 NM_153788
Acap1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr11_-_106860803 6.331 NM_010655
Kpna2
karyopherin (importin) alpha 2
chr9_+_108239210 6.308 Rhoa
ras homolog gene family, member A
chr1_+_59741800 6.242 NM_018868
Nop58
NOP58 ribonucleoprotein homolog (yeast)
chr14_+_71174110 6.235 NM_010071
Dok2
docking protein 2
chr3_+_89904553 6.132 Tpm3
tropomyosin 3, gamma
chr3_+_134875526 6.126 NM_173762
Cenpe
centromere protein E
chr6_-_129187965 6.082 2310001H17Rik
RIKEN cDNA 2310001H17 gene
chr1_+_165992203 6.017 NM_001164059
NM_011346
Sell

selectin, lymphocyte

chr14_-_52780511 5.923 Supt16h
suppressor of Ty 16 homolog (S. cerevisiae)
chr16_+_44867209 5.923 NM_206535
Cd200r2
Cd200 receptor 2
chr1_-_82765022 5.889 NM_025453
Tm4sf20
transmembrane 4 L six family member 20
chr16_+_36935029 5.872 NM_008225
Hcls1
hematopoietic cell specific Lyn substrate 1
chr17_+_46633703 5.769 NM_207161
BC048355
cDNA sequence BC048355
chrX_-_9014351 5.670 Cybb
cytochrome b-245, beta polypeptide
chr19_+_39135495 5.654 NM_028191
Cyp2c65
cytochrome P450, family 2, subfamily c, polypeptide 65
chr1_-_80661844 5.648 Dock10
dedicator of cytokinesis 10
chr11_-_115375672 5.573 NM_008258
Hn1
hematological and neurological expressed sequence 1
chr11_-_83391984 5.545 Ccl9
chemokine (C-C motif) ligand 9
chr14_-_56704033 5.507 NM_008572
Mcpt8
mast cell protease 8
chrX_-_9046362 5.501 NM_007807
Cybb
cytochrome b-245, beta polypeptide
chr13_-_100972022 5.481 NM_001126182
NM_010872
Naip2

NLR family, apoptosis inhibitory protein 2

chr13_-_56280161 5.421 NM_001168615
NM_145976
Tifab

TRAF-interacting protein with forkhead-associated domain, family member B

chr11_-_26493919 5.421 NM_027260
Vrk2
vaccinia related kinase 2
chr12_-_70329149 5.382 NM_011133
Pole2
polymerase (DNA directed), epsilon 2 (p59 subunit)
chr7_+_109614267 5.374 Rrm1
ribonucleotide reductase M1
chr1_-_141677744 5.370 NM_001029977
NM_001160303
NM_001160304
EG214403


predicted gene, EG214403


chr1_-_167865030 5.350 NM_198933
NM_198934
Pou2f1

POU domain, class 2, transcription factor 1

chrX_+_83115611 5.340 NM_001163539
5430427O19Rik
RIKEN cDNA 5430427O19 gene
chr19_-_60842585 5.323 Eif3a
eukaryotic translation initiation factor 3, subunit A
chr11_-_11708917 5.309 NM_001163359
NM_001163360
NM_021891
Fignl1


fidgetin-like 1


chr5_-_121357467 5.273 NM_145211
Oas1a
2'-5' oligoadenylate synthetase 1A
chr6_-_3349415 5.258 Samd9l
sterile alpha motif domain containing 9-like
chr3_+_89904315 5.250


chr2_-_59963796 5.248 NM_001001182
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr8_+_106774774 5.174 NM_029295
NM_001037841
Cklf

chemokine-like factor

chr2_-_59963586 5.164 Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr5_-_92483744 5.160 G3bp2
GTPase activating protein (SH3 domain) binding protein 2
chr5_+_114580397 5.156 NM_001040691
Ung
uracil DNA glycosylase
chr11_-_114851199 5.100 NM_145437
Cd300ld
CD300 molecule-like family member d
chr6_-_65094862 5.088 Hpgds
hematopoietic prostaglandin D synthase
chr11_-_79343891 5.080 Evi2a
ecotropic viral integration site 2a
chr9_-_61794540 5.063 NM_024245
Kif23
kinesin family member 23
chr14_+_75576599 5.033 Lcp1
lymphocyte cytosolic protein 1
chr11_-_83392109 5.019 Ccl9
chemokine (C-C motif) ligand 9
chrX_-_6765768 4.959 NM_016691
Clcn5
chloride channel 5
chr6_-_65094691 4.928 NM_019455
Hpgds
hematopoietic prostaglandin D synthase
chr11_-_82853975 4.907 NM_181542
Slfn10-ps
schlafen 10, pseudogene
chr13_+_52678866 4.887 Sykb
spleen tyrosine kinase
chr12_-_27129497 4.866 Rsad2
radical S-adenosyl methionine domain containing 2
chr6_-_3349470 4.771 NM_010156
Samd9l
sterile alpha motif domain containing 9-like
chr13_-_21879086 4.739 NM_178184
Hist1h2an
histone cluster 1, H2an
chr10_+_82359714 4.735 Txnrd1
thioredoxin reductase 1
chr5_+_8798145 4.723 NM_011075
Abcb1b
ATP-binding cassette, sub-family B (MDR/TAP), member 1B
chr17_-_43013320 4.713 NM_009847
Cd2ap
CD2-associated protein
chr6_+_129543505 4.708 NM_010654
Klrd1
killer cell lectin-like receptor, subfamily D, member 1
chr13_+_51740600 4.689 NM_025415
Cks2
CDC28 protein kinase regulatory subunit 2
chr3_-_135271247 4.686 Nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105
chr17_-_36169573 4.683 NM_010398
H2-T23
histocompatibility 2, T region locus 23
chr6_-_70067577 4.675 Gm10883
predicted gene 10883
chr2_+_90517371 4.662 NM_021512
Nup160
nucleoporin 160
chr5_+_122821868 4.638 Gpn3
GPN-loop GTPase 3
chr13_-_77230519 4.624 Ankrd32
ankyrin repeat domain 32
chr10_+_51210768 4.594 NM_013532
Lilrb4
leukocyte immunoglobulin-like receptor, subfamily B, member 4
chr2_-_25483295 4.590 Fcna
ficolin A
chr1_+_175350728 4.572 NM_001013779
Aim2
absent in melanoma 2
chr3_-_135271190 4.491 Nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105
chr16_-_15966921 4.483 2310008H04Rik
RIKEN cDNA 2310008H04 gene
chr11_-_79344055 4.479 NM_001033711
NM_010161
NM_146023
Evi2a

Evi2b
ecotropic viral integration site 2a

ecotropic viral integration site 2b
chr10_+_42580317 4.449 NM_172938
Scml4
sex comb on midleg-like 4 (Drosophila)
chr14_-_66452720 4.427 NM_028039
Esco2
establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr4_+_107040388 4.361 NM_028355
Tmem48
transmembrane protein 48
chr1_-_175872522 4.333 NM_008328
NM_001045481
Ifi203

interferon activated gene 203

chr17_-_36248574 4.316 H2-T23
C920025E04Rik
histocompatibility 2, T region locus 23
RIKEN cDNA C920025E04 gene
chr3_-_135271220 4.275 Nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105
chr7_-_29678773 4.271 Actn4
actinin alpha 4
chr6_-_38238095 4.240 Zc3hav1l
zinc finger CCCH-type, antiviral 1-like
chr11_+_62416376 4.235 2410006H16Rik
RIKEN cDNA 2410006H16 gene
chr11_-_17853850 4.188 NM_026576
Etaa1
Ewing's tumor-associated antigen 1
chr6_-_130015247 4.166 NM_001039118
Klra4
Klra33
Klra18
killer cell lectin-like receptor, subfamily A, member 4
killer cell lectin-like receptor subfamily A member 33
killer cell lectin-like receptor, subfamily A, member 18
chr9_+_123429291 4.133 Limd1
LIM domains containing 1
chr19_+_39188387 4.126 NM_001011707
Cyp2c66
cytochrome P450, family 2, subfamily c, polypeptide 66
chr6_-_130183339 4.124 NM_001110323
Klra7
killer cell lectin-like receptor, subfamily A, member 7
chr5_-_130478687 4.097 NM_010368
Gusb
glucuronidase, beta
chr17_-_35312945 4.096 NM_019467
Aif1
allograft inflammatory factor 1
chr6_-_122806020 4.092 C3ar1
complement component 3a receptor 1
chr7_+_54106270 4.075 Ldha
lactate dehydrogenase A
chr2_-_180976728 4.004 NM_183162
BC006779
cDNA sequence BC006779
chr6_-_69557773 4.000


chr10_-_61970481 3.972 NM_011157
Srgn
serglycin
chr6_-_122806042 3.965 C3ar1
complement component 3a receptor 1
chr13_+_20277293 3.948 NM_080288
Elmo1
engulfment and cell motility 1, ced-12 homolog (C. elegans)
chr12_+_75028976 3.933 Hif1a
hypoxia inducible factor 1, alpha subunit
chr8_+_67471046 3.929 NM_001163747
NM_028427
Tmem192

transmembrane protein 192

chrX_-_163768423 3.923 NM_133211
Tlr7
toll-like receptor 7
chr13_+_43880475 3.918 NM_009856
Cd83
CD83 antigen
chr9_+_108953672 3.878 Shisa5
shisa homolog 5 (Xenopus laevis)
chr8_+_54597026 3.843 NM_001005847
Aga
aspartylglucosaminidase
chr11_-_86171026 3.842 NM_001080931
Med13
mediator complex subunit 13
chr2_+_152673699 3.818 NM_001141975
NM_001141976
NM_001141977
NM_001141978
NM_028109
Tpx2




TPX2, microtubule-associated protein homolog (Xenopus laevis)




chr5_-_92777875 3.814 NM_021274
Cxcl10
chemokine (C-X-C motif) ligand 10
chr5_+_145888588 3.779 Arpc1b
actin related protein 2/3 complex, subunit 1B
chr6_+_59158860 3.776 NM_001081145
Tigd2
tigger transposable element derived 2
chr19_+_11566527 3.775 NM_001164202
Gm8369
predicted gene 8369
chr1_-_58558259 3.750 NM_001025378
Orc2
origin recognition complex, subunit 2
chr11_-_83392129 3.741 NM_011338
Ccl9
chemokine (C-C motif) ligand 9
chr6_+_136467315 3.722 NM_019426
Atf7ip
activating transcription factor 7 interacting protein
chr13_-_60998747 3.718 NM_001145801
NM_007797
Ctla2b

cytotoxic T lymphocyte-associated protein 2 beta

chr4_-_132352272 3.708 NM_001033308
BC013712
cDNA sequence BC013712
chr11_-_40546863 3.692 NM_013552
Hmmr
hyaluronan mediated motility receptor (RHAMM)
chr6_+_129130632 3.656 NM_053109
Clec2d
C-type lectin domain family 2, member d
chr7_-_128217980 3.629 NM_030691
Igsf6
immunoglobulin superfamily, member 6
chr1_+_61034757 3.627 NM_017480
Icos
inducible T-cell co-stimulator
chrX_-_7182450 3.597 NM_138603
Ccdc22
coiled-coil domain containing 22
chr5_-_100392845 3.586 Hnrnpd
heterogeneous nuclear ribonucleoprotein D
chr7_+_28954717 3.586 NM_007991
Fbl
fibrillarin
chr2_-_26883441 3.560 NM_001177627
NM_172659
Slc2a6

solute carrier family 2 (facilitated glucose transporter), member 6

chr11_-_79337178 3.557 Evi2b
ecotropic viral integration site 2b
chr2_-_169968174 3.549 NM_001159683
Zfp217
zinc finger protein 217
chr4_-_124359695 3.535 Utp11l
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr13_-_55201655 3.526 NM_011307
Uimc1
ubiquitin interaction motif containing 1
chr6_+_41488583 3.515


chr6_-_122806122 3.498 NM_009779
C3ar1
complement component 3a receptor 1
chr5_+_116010796 3.435 Rplp0
ribosomal protein, large, P0
chr16_+_59148654 3.428 NM_146998
Olfr195
olfactory receptor 195
chr3_-_19164956 3.425 NM_008802
Pde7a
phosphodiesterase 7A
chr9_-_44152208 3.400 Hmbs
hydroxymethylbilane synthase
chr7_+_28345494 3.394 NM_001122767
2310022A10Rik
RIKEN cDNA 2310022A10 gene
chr19_+_55255374 3.381 NM_009348
Tectb
tectorin beta
chr11_+_3558702 3.369 NM_198162
Morc2a
microrchidia 2A
chr3_+_95466898 3.351


chr9_+_108953692 3.343 Shisa5
shisa homolog 5 (Xenopus laevis)
chr3_-_95161071 3.341 NM_001163641
NM_001163642
NM_018877
Setdb1


SET domain, bifurcated 1


chr9_+_64809499 3.336 2010321M09Rik
RIKEN cDNA 2010321M09 gene
chr7_-_4014717 3.333 NM_001113474
NM_178611
Lair1

leukocyte-associated Ig-like receptor 1

chr2_+_125977876 3.313 NM_026981
Dtwd1
DTW domain containing 1
chr19_+_29218114 3.305


chr2_-_167515255 3.288 Tmem189
transmembrane protein 189
chr1_+_173770709 3.288 NM_013489
Cd84
CD84 antigen
chr9_+_44887251 3.281 NM_001005421
Amica1
adhesion molecule, interacts with CXADR antigen 1
chr6_-_69193672 3.281


chr4_-_142718290 3.257 Prdm2
PR domain containing 2, with ZNF domain
chr7_+_148586221 3.255 Taldo1
transaldolase 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.78 1.27e-03 GO:0006396 RNA processing
1.53 9.19e-03 GO:0002376 immune system process
1.36 3.16e-02 GO:0006950 response to stress
1.67 4.57e-02 GO:0006952 defense response

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.49 4.61e-07 GO:0044428 nuclear part
1.38 6.76e-04 GO:0031974 membrane-enclosed lumen
1.20 7.64e-04 GO:0005634 nucleus
1.39 8.29e-04 GO:0070013 intracellular organelle lumen
1.38 9.35e-04 GO:0043233 organelle lumen
1.41 1.40e-03 GO:0031981 nuclear lumen
2.07 7.08e-03 GO:0009897 external side of plasma membrane
1.68 9.26e-03 GO:0030529 ribonucleoprotein complex
4.67 2.17e-02 GO:0030532 small nuclear ribonucleoprotein complex
1.41 4.07e-02 GO:0005654 nucleoplasm
1.70 4.55e-02 GO:0005730 nucleolus

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.65 4.44e-04 GO:0003723 RNA binding
1.26 2.03e-02 GO:0003676 nucleic acid binding