Motif ID: ZBTB6.p2

Z-value: 2.394


Transcription factors associated with ZBTB6.p2:

Gene SymbolEntrez IDGene Name
Zbtb6 241322 zinc finger and BTB domain containing 6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb6chr2_-_37286367-0.009.5e-01Click!


Activity profile for motif ZBTB6.p2.

activity profile for motif ZBTB6.p2


Sorted Z-values histogram for motif ZBTB6.p2

Sorted Z-values for motif ZBTB6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_73509668 75.285 Rtn1
reticulon 1
chr12_-_73509537 59.232 Rtn1
reticulon 1
chr15_+_78744328 53.931 NM_020271
 Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr18_-_25912171 42.968 Celf4
CUGBP, Elav-like family member 4
chr11_+_83223154 41.550 Rasl10b
RAS-like, family 10, member B
chr11_+_83223573 39.635 NM_001013386
 Rasl10b
RAS-like, family 10, member B
chr3_+_34548916 35.741 NM_011443
 Sox2
SRY-box containing gene 2
chr8_+_96334879 33.166 Gnao1
guanine nucleotide binding protein, alpha O
chr15_+_91881593 32.294 NM_001159648
 Cntn1
contactin 1
chr12_-_73509925 30.816 NM_153457
 Rtn1
reticulon 1
chr3_+_34549057 28.995 Sox2
SRY-box containing gene 2
chr6_+_110595586 28.955 NM_177328
 Grm7
glutamate receptor, metabotropic 7
chr1_-_75260687 28.935 NM_008985
 Ptprn
protein tyrosine phosphatase, receptor type, N
chr14_-_13655592 28.039 NM_001042617
NM_012061
 Cadps

Ca2+-dependent secretion activator

chr14_-_13655558 27.740 Cadps
Ca2+-dependent secretion activator
chr15_-_98637560 27.186 Ddn
dendrin
chr7_-_31230564 26.384 Aplp1
amyloid beta (A4) precursor-like protein 1
chr18_-_43058544 25.164 NM_027531
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr11_-_69373555 24.825 Efnb3
ephrin B3
chr7_-_31230577 24.817 NM_007467
 Aplp1
amyloid beta (A4) precursor-like protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 72 entries
Enrichment   P-value GO Accession GO Term
11.76 1.20e-02 GO:0021681 cerebellar granular layer development
11.76 1.20e-02 GO:0021683 cerebellar granular layer morphogenesis
10.08 6.60e-03 GO:0048172 regulation of short-term neuronal synaptic plasticity
4.46 3.61e-02 GO:0048169 regulation of long-term neuronal synaptic plasticity
4.10 3.43e-03 GO:0048168 regulation of neuronal synaptic plasticity
3.74 2.65e-02 GO:0007269 neurotransmitter secretion
3.39 4.87e-02 GO:0014013 regulation of gliogenesis
3.23 2.53e-04 GO:0006836 neurotransmitter transport
3.21 3.03e-03 GO:0048167 regulation of synaptic plasticity
2.70 2.11e-05 GO:0010975 regulation of neuron projection development
2.66 2.24e-03 GO:0033124 regulation of GTP catabolic process
2.59 6.11e-03 GO:0043087 regulation of GTPase activity
2.50 6.57e-05 GO:0031344 regulation of cell projection organization
2.43 1.08e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.43 1.08e-02 GO:0022604 regulation of cell morphogenesis
2.43 1.08e-02 GO:0030811 regulation of nucleotide catabolic process
2.43 1.08e-02 GO:0033121 regulation of purine nucleotide catabolic process
2.33 1.37e-05 GO:0045664 regulation of neuron differentiation
2.28 7.35e-05 GO:0007268 synaptic transmission
2.25 1.01e-03 GO:0031644 regulation of neurological system process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 49 entries
Enrichment   P-value GO Accession GO Term
4.95 3.53e-02 GO:0008328 ionotropic glutamate receptor complex
3.71 1.87e-02 GO:0043198 dendritic shaft
3.53 3.29e-02 GO:0042734 presynaptic membrane
2.94 2.86e-06 GO:0019717 synaptosome
2.94 4.74e-06 GO:0033267 axon part
2.73 2.88e-03 GO:0008021 synaptic vesicle
2.71 3.05e-02 GO:0043679 axon terminus
2.66 2.61e-02 GO:0044306 neuron projection terminus
2.52 4.85e-09 GO:0030425 dendrite
2.48 6.22e-10 GO:0043025 neuronal cell body
2.47 2.62e-10 GO:0044297 cell body
2.37 1.15e-15 GO:0043005 neuron projection
2.37 9.00e-09 GO:0044456 synapse part
2.35 1.93e-06 GO:0030424 axon
2.32 3.03e-12 GO:0045202 synapse
2.26 5.30e-03 GO:0045211 postsynaptic membrane
2.26 1.47e-02 GO:0030136 clathrin-coated vesicle
2.04 2.33e-06 GO:0044463 cell projection part
2.01 4.59e-04 GO:0048471 perinuclear region of cytoplasm
1.88 1.62e-13 GO:0042995 cell projection

Gene overrepresentation in function category:

Showing 1 to 20 of 25 entries
Enrichment   P-value GO Accession GO Term
4.41 4.17e-03 GO:0035254 glutamate receptor binding
2.05 2.36e-03 GO:0005083 small GTPase regulator activity
1.82 1.98e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.78 4.73e-03 GO:0004674 protein serine/threonine kinase activity
1.78 6.24e-03 GO:0030695 GTPase regulator activity
1.75 1.78e-05 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.71 8.76e-04 GO:0004672 protein kinase activity
1.70 1.05e-05 GO:0016301 kinase activity
1.64 2.53e-02 GO:0008324 cation transmembrane transporter activity
1.62 2.44e-02 GO:0008092 cytoskeletal protein binding
1.61 3.80e-05 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.60 2.54e-04 GO:0019899 enzyme binding
1.55 2.12e-03 GO:0030234 enzyme regulator activity
1.45 3.75e-02 GO:0022892 substrate-specific transporter activity
1.42 5.83e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.42 1.31e-03 GO:0005524 ATP binding
1.41 9.50e-05 GO:0017076 purine nucleotide binding
1.41 1.08e-04 GO:0032555 purine ribonucleotide binding
1.41 1.13e-04 GO:0032553 ribonucleotide binding
1.41 1.43e-03 GO:0030554 adenyl nucleotide binding