Motif ID: ZEB1.p2

Z-value: 2.499


Transcription factors associated with ZEB1.p2:

Gene SymbolEntrez IDGene Name
Zeb1 21417 zinc finger E-box binding homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zeb1chr18_+_55918690.137.3e-02Click!


Activity profile for motif ZEB1.p2.

activity profile for motif ZEB1.p2


Sorted Z-values histogram for motif ZEB1.p2

Sorted Z-values for motif ZEB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZEB1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_30066910 97.441 NM_001082548
NM_011464
 Spint2

serine protease inhibitor, Kunitz type 2

chr7_-_30066867 95.781 Spint2
serine protease inhibitor, Kunitz type 2
chr7_-_30066642 90.330 Spint2
serine protease inhibitor, Kunitz type 2
chr15_+_54402988 59.521 Mal2
mal, T-cell differentiation protein 2
chr12_-_74647339 57.902 NM_178715
 Tmem30b
transmembrane protein 30B
chr8_+_109127245 52.823 NM_009864
 Cdh1
cadherin 1
chr11_+_69778998 51.535 Cldn7
claudin 7
chr15_+_54402914 51.138 NM_178920
 Mal2
mal, T-cell differentiation protein 2
chr8_+_3587791 45.179 2310057J16Rik
RIKEN cDNA 2310057J16 gene
chr11_+_69778907 43.492 NM_016887
 Cldn7
claudin 7
chr4_-_11313886 40.391 NM_194055
 Esrp1
epithelial splicing regulatory protein 1
chr8_+_3587675 37.133 2310057J16Rik
RIKEN cDNA 2310057J16 gene
chr16_+_91270319 36.383 Olig1
oligodendrocyte transcription factor 1
chr17_+_88036128 34.834 Epcam
epithelial cell adhesion molecule
chr11_-_35793590 34.262 NM_170779
 Wwc1
WW, C2 and coiled-coil domain containing 1
chr7_-_31758390 33.748 NM_001164184
NM_001164185
NM_017405
 Lsr


lipolysis stimulated lipoprotein receptor


chrX_+_162676903 33.249 Gpm6b
glycoprotein m6b
chr17_+_57201623 32.778 NM_177638
 Crb3
crumbs homolog 3 (Drosophila)
chr1_+_194979305 30.491 NM_016851
 Irf6
interferon regulatory factor 6
chr8_-_41720091 30.289 NM_001040699
 Mtmr7
myotubularin related protein 7

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 29 entries
Enrichment   P-value GO Accession GO Term
2.54 2.27e-03 GO:0006836 neurotransmitter transport
2.02 4.48e-02 GO:0030811 regulation of nucleotide catabolic process
2.02 4.48e-02 GO:0033121 regulation of purine nucleotide catabolic process
1.99 1.39e-02 GO:0010975 regulation of neuron projection development
1.93 6.04e-03 GO:0016337 cell-cell adhesion
1.92 1.18e-03 GO:0051056 regulation of small GTPase mediated signal transduction
1.91 1.60e-02 GO:0031344 regulation of cell projection organization
1.84 2.84e-02 GO:0046578 regulation of Ras protein signal transduction
1.81 5.14e-03 GO:0045664 regulation of neuron differentiation
1.74 3.89e-03 GO:0050767 regulation of neurogenesis
1.72 8.62e-03 GO:0009894 regulation of catabolic process
1.62 3.79e-02 GO:0051960 regulation of nervous system development
1.50 3.46e-03 GO:0055085 transmembrane transport
1.49 1.89e-02 GO:0022610 biological adhesion
1.49 2.10e-02 GO:0007155 cell adhesion
1.46 3.50e-03 GO:0051128 regulation of cellular component organization
1.46 7.41e-03 GO:0048699 generation of neurons
1.42 2.74e-04 GO:0007399 nervous system development
1.42 2.52e-02 GO:0022008 neurogenesis
1.38 2.42e-03 GO:0009966 regulation of signal transduction

Gene overrepresentation in compartment category:

Showing 1 to 20 of 39 entries
Enrichment   P-value GO Accession GO Term
2.89 4.01e-02 GO:0042734 presynaptic membrane
2.49 3.80e-04 GO:0016327 apicolateral plasma membrane
2.38 2.40e-03 GO:0043296 apical junction complex
2.23 4.90e-02 GO:0005923 tight junction
2.23 4.90e-02 GO:0070160 occluding junction
2.18 2.08e-02 GO:0008021 synaptic vesicle
2.09 6.59e-03 GO:0005912 adherens junction
2.02 8.58e-03 GO:0070161 anchoring junction
2.01 4.99e-04 GO:0016324 apical plasma membrane
1.94 4.54e-07 GO:0044456 synapse part
1.89 1.69e-09 GO:0045202 synapse
1.88 3.04e-04 GO:0045177 apical part of cell
1.88 8.01e-04 GO:0005911 cell-cell junction
1.86 3.33e-02 GO:0030135 coated vesicle
1.78 1.25e-09 GO:0030054 cell junction
1.78 2.58e-03 GO:0030424 axon
1.75 1.80e-05 GO:0044463 cell projection part
1.69 1.04e-06 GO:0043005 neuron projection
1.67 1.59e-02 GO:0015629 actin cytoskeleton
1.52 7.10e-08 GO:0042995 cell projection

Gene overrepresentation in function category:

Showing 1 to 16 of 16 entries
Enrichment   P-value GO Accession GO Term
2.38 1.16e-02 GO:0005099 Ras GTPase activator activity
2.26 2.34e-02 GO:0030165 PDZ domain binding
2.11 6.08e-07 GO:0005083 small GTPase regulator activity
2.10 2.58e-03 GO:0015077 monovalent inorganic cation transmembrane transporter activity
2.02 1.16e-02 GO:0005085 guanyl-nucleotide exchange factor activity
1.98 1.66e-06 GO:0003779 actin binding
1.96 1.42e-08 GO:0030695 GTPase regulator activity
1.93 3.07e-03 GO:0022890 inorganic cation transmembrane transporter activity
1.90 9.05e-08 GO:0060589 nucleoside-triphosphatase regulator activity
1.87 1.77e-09 GO:0008092 cytoskeletal protein binding
1.65 2.24e-02 GO:0008047 enzyme activator activity
1.64 3.08e-02 GO:0022804 active transmembrane transporter activity
1.58 4.33e-07 GO:0030234 enzyme regulator activity
1.52 1.26e-02 GO:0008324 cation transmembrane transporter activity
1.23 3.57e-11 GO:0005515 protein binding
1.14 3.92e-12 GO:0005488 binding