Motif ID: ZEB1.p2

Z-value: 2.499


Transcription factors associated with ZEB1.p2:

Gene SymbolEntrez IDGene Name
Zeb1 21417 zinc finger E-box binding homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zeb1chr18_+_55918690.137.3e-02Click!


Activity profile for motif ZEB1.p2.

activity profile for motif ZEB1.p2


Sorted Z-values histogram for motif ZEB1.p2

Sorted Z-values for motif ZEB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZEB1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_30066910 97.441 NM_001082548
NM_011464
Spint2

serine protease inhibitor, Kunitz type 2

chr7_-_30066867 95.781 Spint2
serine protease inhibitor, Kunitz type 2
chr7_-_30066642 90.330 Spint2
serine protease inhibitor, Kunitz type 2
chr15_+_54402988 59.521 Mal2
mal, T-cell differentiation protein 2
chr12_-_74647339 57.902 NM_178715
Tmem30b
transmembrane protein 30B
chr8_+_109127245 52.823 NM_009864
Cdh1
cadherin 1
chr11_+_69778998 51.535 Cldn7
claudin 7
chr15_+_54402914 51.138 NM_178920
Mal2
mal, T-cell differentiation protein 2
chr8_+_3587791 45.179 2310057J16Rik
RIKEN cDNA 2310057J16 gene
chr11_+_69778907 43.492 NM_016887
Cldn7
claudin 7
chr4_-_11313886 40.391 NM_194055
Esrp1
epithelial splicing regulatory protein 1
chr8_+_3587675 37.133 2310057J16Rik
RIKEN cDNA 2310057J16 gene
chr16_+_91270319 36.383 Olig1
oligodendrocyte transcription factor 1
chr17_+_88036128 34.834 Epcam
epithelial cell adhesion molecule
chr11_-_35793590 34.262 NM_170779
Wwc1
WW, C2 and coiled-coil domain containing 1
chr7_-_31758390 33.748 NM_001164184
NM_001164185
NM_017405
Lsr


lipolysis stimulated lipoprotein receptor


chrX_+_162676903 33.249 Gpm6b
glycoprotein m6b
chr17_+_57201623 32.778 NM_177638
Crb3
crumbs homolog 3 (Drosophila)
chr1_+_194979305 30.491 NM_016851
Irf6
interferon regulatory factor 6
chr8_-_41720091 30.289 NM_001040699
Mtmr7
myotubularin related protein 7
chrX_+_162676870 30.104 NM_001177961
NM_001177962
NM_023122
Gpm6b


glycoprotein m6b


chr2_+_25258568 30.037 NM_008721
Npdc1
neural proliferation, differentiation and control gene 1
chr2_+_25258653 29.061 Npdc1
neural proliferation, differentiation and control gene 1
chr3_-_55987612 28.486 NM_030595
Nbea
neurobeachin
chr18_+_74602260 27.963 NM_201600
Myo5b
myosin VB
chr11_-_105805442 27.121 NM_007805
Cyb561
cytochrome b-561
chr8_+_3587449 26.616 NM_001163749
NM_027171
2310057J16Rik

RIKEN cDNA 2310057J16 gene

chr8_+_12915892 26.082 NM_178076
Mcf2l
mcf.2 transforming sequence-like
chr7_-_31758185 25.608 Lsr
lipolysis stimulated lipoprotein receptor
chr2_+_90730089 25.532 C1qtnf4
C1q and tumor necrosis factor related protein 4
chr1_+_120524521 25.488 NM_023755
Tcfcp2l1
transcription factor CP2-like 1
chr17_+_88035996 25.442 Epcam
epithelial cell adhesion molecule
chr13_-_101322557 25.207 Ocln
occludin
chr1_-_79855209 25.007 Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr13_-_101322672 24.561 Ocln
occludin
chr10_-_18463500 24.371 NM_001033258
D10Bwg1379e
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chr16_+_91270009 22.736 NM_016968
Olig1
oligodendrocyte transcription factor 1
chr4_+_133074877 22.479 NM_001083916
NM_133707
1810019J16Rik

RIKEN cDNA 1810019J16 gene

chr12_+_113960424 22.282 AW555464
expressed sequence AW555464
chr18_+_20716598 22.197 NM_007883
Dsg2
desmoglein 2
chr8_+_86424565 22.178 Lphn1
latrophilin 1
chr12_+_113960530 22.143 AW555464
expressed sequence AW555464
chr13_-_101322416 21.555 NM_008756
Ocln
occludin
chr4_+_137263376 21.517 Rap1gap
Rap1 GTPase-activating protein
chr1_+_78306890 21.350 NM_001004173
Sgpp2
sphingosine-1-phosphate phosphotase 2
chr2_+_119063090 21.337 NM_016907
Spint1
serine protease inhibitor, Kunitz type 1
chr7_-_20281956 21.153


chr2_+_119063134 20.363 Spint1
serine protease inhibitor, Kunitz type 1
chr4_+_133074976 20.259 1810019J16Rik
RIKEN cDNA 1810019J16 gene
chr11_-_100259048 20.250 NM_010593
Jup
junction plakoglobin
chr2_+_119063194 20.217


chr15_-_78633301 20.184 NM_130859
Card10
caspase recruitment domain family, member 10
chr14_+_30822097 20.084 NM_001136240
Chdh
choline dehydrogenase
chr11_+_115685417 20.002 Llgl2
lethal giant larvae homolog 2 (Drosophila)
chr1_-_79855229 19.971 NM_009255
Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr1_-_79855177 19.918 Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr19_+_6306456 19.885 NM_001033342
Cdc42bpg
CDC42 binding protein kinase gamma (DMPK-like)
chr17_+_88036047 19.865 Epcam
epithelial cell adhesion molecule
chr16_-_97985323 19.158 NM_023663
Ripk4
receptor-interacting serine-threonine kinase 4
chr6_+_4853319 18.821 NM_181595
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr9_-_95745663 18.790 NM_001033210
Pls1
plastin 1 (I-isoform)
chr11_+_115685365 18.695 NM_145438
Llgl2
lethal giant larvae homolog 2 (Drosophila)
chr4_-_151235861 18.494 NM_001081557
NM_001195565
Camta1

calmodulin binding transcription activator 1

chr8_-_108660711 18.288 Esrp2
epithelial splicing regulatory protein 2
chr13_+_97841524 18.021 NM_001100458
Fam169a
family with sequence similarity 169, member A
chr16_+_16213397 17.825 Pkp2
plakophilin 2
chr5_+_37637027 17.727 NM_007765
Crmp1
collapsin response mediator protein 1
chrX_+_97972559 17.531 NM_001177780
Dlg3
discs, large homolog 3 (Drosophila)
chr5_-_44492908 17.508 NM_001163577
NM_008935
Prom1

prominin 1

chr3_+_121129396 17.418 NM_028044
Cnn3
calponin 3, acidic
chr14_-_71035662 17.355 Epb4.9
erythrocyte protein band 4.9
chr8_+_109127326 17.282 Cdh1
cadherin 1
chr5_-_17866110 17.247 NM_010305
Gnai1
guanine nucleotide binding protein (G protein), alpha inhibiting 1
chr2_+_90729768 17.086 C1qtnf4
C1q and tumor necrosis factor related protein 4
chr4_-_133794246 16.735 NM_001081047
Cnksr1
connector enhancer of kinase suppressor of Ras 1
chr14_+_102129129 16.598 NM_201529
Lmo7
LIM domain only 7
chr16_+_16213434 16.580 NM_026163
Pkp2
plakophilin 2
chr8_-_108660736 16.286 NM_176838
Esrp2
epithelial splicing regulatory protein 2
chr2_+_126378563 15.917 NM_011978
Slc27a2
solute carrier family 27 (fatty acid transporter), member 2
chr1_-_89406861 15.696 NM_019867
Ngef
neuronal guanine nucleotide exchange factor
chr17_+_28906259 15.634 NM_011950
Mapk13
mitogen-activated protein kinase 13
chr11_-_20731016 15.566 NM_173752
1110067D22Rik
RIKEN cDNA 1110067D22 gene
chr2_+_167906462 15.318 NM_021409
Pard6b
par-6 (partitioning defective 6) homolog beta (C. elegans)
chr19_-_36811137 15.155 Ppp1r3c
protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr7_+_148401781 15.130 Rassf7
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr2_-_37558794 15.035 Strbp
spermatid perinuclear RNA binding protein
chr9_-_29219306 14.986 Ntm
neurotrimin
chr14_-_8491067 14.972 Gm2897
predicted gene 2897
chr19_-_36811090 14.868 NM_016854
Ppp1r3c
protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr9_+_36640268 14.863 Fez1
fasciculation and elongation protein zeta 1 (zygin I)
chr4_+_133074949 14.748 1810019J16Rik
RIKEN cDNA 1810019J16 gene
chr8_-_112486020 14.730 NM_028584
NM_212447
Marveld3

MARVEL (membrane-associating) domain containing 3

chr11_-_115229039 14.711 C630004H02Rik
RIKEN cDNA C630004H02 gene
chr8_-_113917651 14.270 NM_178086
Fa2h
fatty acid 2-hydroxylase
chr1_+_137715174 14.266 NM_133664
Lad1
ladinin
chr13_+_38243146 14.145 NM_023842
Dsp
desmoplakin
chr9_-_29219382 14.024 Ntm
neurotrimin
chr11_-_100259061 13.983 Jup
junction plakoglobin
chr4_+_95634005 13.960 NM_030014
Hook1
hook homolog 1 (Drosophila)
chr6_+_88674398 13.863 NM_001166249
NM_011844
Mgll

monoglyceride lipase

chr13_-_34437042 13.706 NM_001033167
Slc22a23
solute carrier family 22, member 23
chr15_-_75839859 13.339 NM_001168253
Fam83h
family with sequence similarity 83, member H
chrX_+_5624624 13.327 NM_021431
Nudt11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr7_-_106331080 13.306 NM_026384
Dgat2
diacylglycerol O-acyltransferase 2
chr6_-_134582365 13.255 NM_026345
Mansc1
MANSC domain containing 1
chrX_+_5624820 13.118 Nudt11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr4_+_84851330 12.924 NM_019535
Sh3gl2
SH3-domain GRB2-like 2
chr3_-_57651621 12.898 NM_019410
Pfn2
profilin 2
chr11_-_35793951 12.869 Wwc1
WW, C2 and coiled-coil domain containing 1
chr1_-_166388431 12.799 NM_009721
Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr9_+_120213190 12.764 NM_144557
Myrip
myosin VIIA and Rab interacting protein
chr7_-_4741145 12.664 NM_029384
2210411K11Rik
RIKEN cDNA 2210411K11 gene
chr12_+_114378368 12.514 NM_024223
Crip2
cysteine rich protein 2
chr16_-_18629938 12.404 NM_213614
Sept5
septin 5
chr5_+_135462067 12.388 NM_009902
Cldn3
claudin 3
chrX_+_155852439 12.326 NM_001081124
Mtap7d2
MAP7 domain containing 2
chr14_-_7937970 12.299 NM_001024712
Gm3696
predicted gene 3696
chr6_+_48487648 12.016 Atp6v0e2
ATPase, H+ transporting, lysosomal V0 subunit E2
chr4_-_129952771 12.007 NM_172702
Serinc2
serine incorporator 2
chr19_-_24299471 11.998 NM_011597
Tjp2
tight junction protein 2
chr14_+_3049284 11.949 NM_001177715
NM_001177714
Gm2897

predicted gene 2897

chr13_-_62989500 11.930 Fbp1
fructose bisphosphatase 1
chr4_+_104040160 11.924 NM_010014
NM_177259
Dab1

disabled homolog 1 (Drosophila)

chr4_+_43071801 11.754 Unc13b
unc-13 homolog B (C. elegans)
chr5_-_140290195 11.721 NM_001161548
Tmem184a
transmembrane protein 184a
chr2_-_148558110 11.662 NM_019632
Napb
N-ethylmaleimide sensitive fusion protein attachment protein beta
chr6_+_48487567 11.588 NM_133764
Atp6v0e2
ATPase, H+ transporting, lysosomal V0 subunit E2
chr15_-_34608458 11.576 NM_145469
Nipal2
NIPA-like domain containing 2
chr4_+_101169252 11.575 NM_198412
Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr8_-_4259126 11.541 NM_183315
Ctxn1
cortexin 1
chr11_-_83881811 11.495 NM_019819
Dusp14
dual specificity phosphatase 14
chr14_-_7859962 11.465 NM_001164727
Gm10406
predicted gene 10406
chr11_-_80593259 11.202 NM_177390
Myo1d
myosin ID
chr6_+_91106773 11.125 NM_144919
Hdac11
histone deacetylase 11
chr12_+_80130149 11.071 NM_181073
Plekhh1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr5_+_124423632 10.985 NM_145070
Hip1r
huntingtin interacting protein 1 related
chr9_-_21397188 10.846 NM_138303
Yipf2
Yip1 domain family, member 2
chr19_-_24299389 10.820 Tjp2
tight junction protein 2
chr8_-_63461923 10.810 Clcn3
chloride channel 3
chr12_+_85350438 10.803 NM_012006
Acot1
acyl-CoA thioesterase 1
chr7_+_148401731 10.738 NM_025886
Rassf7
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr4_+_148960536 10.710 Clstn1
calsyntenin 1
chr2_+_138082301 10.543 NM_001025431
Btbd3
BTB (POZ) domain containing 3
chr12_-_80007923 10.542 NM_013738
Plek2
pleckstrin 2
chr12_+_113960379 10.452 NM_001024602
AW555464
expressed sequence AW555464
chr6_-_92656148 10.393 NM_001081146
Prickle2
prickle homolog 2 (Drosophila)
chr3_+_62142698 10.379 NM_001081295
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr10_+_61111426 10.354 Ppa1
pyrophosphatase (inorganic) 1
chr17_+_87153083 10.351 NM_010137
Epas1
endothelial PAS domain protein 1
chr11_+_98308333 10.333 Grb7
growth factor receptor bound protein 7
chrX_-_132749976 10.291 NM_009052
Bex1
brain expressed gene 1
chr6_-_137118238 10.277 NM_001164212
NM_001164214
Rerg

RAS-like, estrogen-regulated, growth-inhibitor

chr12_-_58646914 10.248 Foxa1
forkhead box A1
chr12_-_58647074 10.137 NM_008259
Foxa1
forkhead box A1
chr4_-_153673990 10.135 NM_001112744
Arhgef16
Rho guanine nucleotide exchange factor (GEF) 16
chr7_+_108470264 10.120 Stard10
START domain containing 10
chr1_+_137715339 10.074 Lad1
ladinin
chr3_-_88351996 10.024 NM_016899
Rab25
RAB25, member RAS oncogene family
chr5_-_145118920 10.018 NM_025833
Baiap2l1
BAI1-associated protein 2-like 1
chr7_-_3629111 9.998 NM_181820
Tmc4
transmembrane channel-like gene family 4
chr6_-_137118197 9.983 Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr9_+_69137659 9.905 Rora
RAR-related orphan receptor alpha
chr13_-_25029458 9.881 NM_172532
Aldh5a1
aldhehyde dehydrogenase family 5, subfamily A1
chr3_-_94590356 9.813 NM_001037711
Cgn
cingulin
chr18_-_34166859 9.787 NM_013512
Epb4.1l4a
erythrocyte protein band 4.1-like 4a
chrX_-_70905384 9.763 Pnck
pregnancy upregulated non-ubiquitously expressed CaM kinase
chr7_-_3629066 9.718 Tmc4
transmembrane channel-like gene family 4
chr5_-_63157309 9.636 NM_178407
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr8_-_92872139 9.628 NM_172913
Tox3
TOX high mobility group box family member 3
chr14_-_122196929 9.621 NM_134074
Dock9
dedicator of cytokinesis 9
chr14_-_57723453 9.603 Gjb2
gap junction protein, beta 2
chr7_-_51920870 9.600 NM_028021
Myh14
myosin, heavy polypeptide 14
chr1_-_155033576 9.598 NM_008485
Lamc2
laminin, gamma 2
chr17_+_43938789 9.588 NM_207649
Rcan2
regulator of calcineurin 2
chr16_-_18089085 9.535 NM_011172
Prodh
proline dehydrogenase
chr10_+_61111331 9.529 NM_026438
Ppa1
pyrophosphatase (inorganic) 1
chr13_-_62989520 9.519 Fbp1
fructose bisphosphatase 1
chr5_+_124423712 9.516 Hip1r
huntingtin interacting protein 1 related
chr15_+_38837818 9.473 NM_001162494
Fzd6
frizzled homolog 6 (Drosophila)
chr15_+_38837839 9.450 NM_008056
Fzd6
frizzled homolog 6 (Drosophila)
chr4_+_43071852 9.449 NM_001081413
NM_021468
Unc13b

unc-13 homolog B (C. elegans)

chr15_-_37721754 9.423 NM_001170866
Ncald
neurocalcin delta
chr2_+_49474840 9.392 Kif5c
kinesin family member 5C
chr10_-_79600131 9.373 NM_001195268
Dos
downstream of Stk11
chr7_+_36119340 9.358 Rhpn2
rhophilin, Rho GTPase binding protein 2
chr4_+_129662110 9.347 Bai2
brain-specific angiogenesis inhibitor 2
chr11_-_12364886 9.337 NM_172496
Cobl
cordon-bleu
chr7_+_36119255 9.334 NM_027897
Rhpn2
rhophilin, Rho GTPase binding protein 2
chr7_+_17529961 9.324 NM_001099636
Pnmal2
PNMA-like 2
chr5_+_148768875 9.213 NM_029920
Mtus2
microtubule associated tumor suppressor candidate 2
chr11_-_94938114 9.174 Itga3
integrin alpha 3
chr9_-_99258896 9.130 NM_177775
Esyt3
extended synaptotagmin-like protein 3
chr15_-_37722161 9.123 NM_134094
Ncald
neurocalcin delta
chr11_-_100007218 9.121 NM_008471
Krt19
keratin 19
chr17_-_35838974 9.086 NM_001198831
Ddr1
discoidin domain receptor family, member 1
chr8_-_48374715 9.066 Stox2
storkhead box 2
chr9_+_108997946 9.065 NM_172775
Plxnb1
plexin B1
chr16_-_85173764 9.034 App
amyloid beta (A4) precursor protein
chr3_-_81878554 9.018 NM_001161796
NM_017469
Gucy1b3

guanylate cyclase 1, soluble, beta 3

chr9_+_69137694 8.939 Rora
RAR-related orphan receptor alpha

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.30 9.68e-08 GO:0051179 localization
1.31 9.08e-07 GO:0006810 transport
1.30 2.01e-06 GO:0051234 establishment of localization
1.42 2.74e-04 GO:0007399 nervous system development
1.35 2.98e-04 GO:0044281 small molecule metabolic process
1.92 1.18e-03 GO:0051056 regulation of small GTPase mediated signal transduction
1.34 2.21e-03 GO:0023051 regulation of signaling
2.54 2.27e-03 GO:0006836 neurotransmitter transport
1.22 2.35e-03 GO:0032502 developmental process
1.38 2.42e-03 GO:0009966 regulation of signal transduction
1.22 3.27e-03 GO:0007275 multicellular organismal development
1.50 3.46e-03 GO:0055085 transmembrane transport
1.46 3.50e-03 GO:0051128 regulation of cellular component organization
1.74 3.89e-03 GO:0050767 regulation of neurogenesis
1.23 4.54e-03 GO:0048856 anatomical structure development
1.81 5.14e-03 GO:0045664 regulation of neuron differentiation
1.25 5.24e-03 GO:0048731 system development
1.93 6.04e-03 GO:0016337 cell-cell adhesion
1.46 7.41e-03 GO:0048699 generation of neurons
1.72 8.62e-03 GO:0009894 regulation of catabolic process
1.99 1.39e-02 GO:0010975 regulation of neuron projection development
1.91 1.60e-02 GO:0031344 regulation of cell projection organization
1.49 1.89e-02 GO:0022610 biological adhesion
1.49 2.10e-02 GO:0007155 cell adhesion
1.42 2.52e-02 GO:0022008 neurogenesis
1.84 2.84e-02 GO:0046578 regulation of Ras protein signal transduction
1.62 3.79e-02 GO:0051960 regulation of nervous system development
2.02 4.48e-02 GO:0030811 regulation of nucleotide catabolic process
2.02 4.48e-02 GO:0033121 regulation of purine nucleotide catabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.17 7.54e-19 GO:0005622 intracellular
1.21 2.43e-17 GO:0005737 cytoplasm
1.16 1.44e-15 GO:0044424 intracellular part
1.78 1.25e-09 GO:0030054 cell junction
1.89 1.69e-09 GO:0045202 synapse
1.28 2.23e-09 GO:0071944 cell periphery
1.21 1.03e-08 GO:0044444 cytoplasmic part
1.27 1.71e-08 GO:0005886 plasma membrane
1.52 7.10e-08 GO:0042995 cell projection
1.07 3.24e-07 GO:0005623 cell
1.07 3.24e-07 GO:0044464 cell part
1.94 4.54e-07 GO:0044456 synapse part
1.12 8.76e-07 GO:0043226 organelle
1.69 1.04e-06 GO:0043005 neuron projection
1.12 1.35e-06 GO:0043229 intracellular organelle
1.36 1.36e-06 GO:0044459 plasma membrane part
1.39 9.03e-06 GO:0005856 cytoskeleton
1.75 1.80e-05 GO:0044463 cell projection part
1.88 3.04e-04 GO:0045177 apical part of cell
2.49 3.80e-04 GO:0016327 apicolateral plasma membrane
2.01 4.99e-04 GO:0016324 apical plasma membrane
1.88 8.01e-04 GO:0005911 cell-cell junction
2.38 2.40e-03 GO:0043296 apical junction complex
1.78 2.58e-03 GO:0030424 axon
2.09 6.59e-03 GO:0005912 adherens junction
2.02 8.58e-03 GO:0070161 anchoring junction
1.36 9.85e-03 GO:0005794 Golgi apparatus
1.10 9.97e-03 GO:0016020 membrane
1.67 1.59e-02 GO:0015629 actin cytoskeleton
1.36 1.61e-02 GO:0044430 cytoskeletal part
2.18 2.08e-02 GO:0008021 synaptic vesicle
1.35 2.53e-02 GO:0005626 insoluble fraction
1.45 3.31e-02 GO:0031988 membrane-bounded vesicle
1.86 3.33e-02 GO:0030135 coated vesicle
1.09 3.71e-02 GO:0043227 membrane-bounded organelle
2.89 4.01e-02 GO:0042734 presynaptic membrane
1.09 4.32e-02 GO:0043231 intracellular membrane-bounded organelle
2.23 4.90e-02 GO:0005923 tight junction
2.23 4.90e-02 GO:0070160 occluding junction

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.14 3.92e-12 GO:0005488 binding
1.23 3.57e-11 GO:0005515 protein binding
1.87 1.77e-09 GO:0008092 cytoskeletal protein binding
1.96 1.42e-08 GO:0030695 GTPase regulator activity
1.90 9.05e-08 GO:0060589 nucleoside-triphosphatase regulator activity
1.58 4.33e-07 GO:0030234 enzyme regulator activity
2.11 6.08e-07 GO:0005083 small GTPase regulator activity
1.98 1.66e-06 GO:0003779 actin binding
2.10 2.58e-03 GO:0015077 monovalent inorganic cation transmembrane transporter activity
1.93 3.07e-03 GO:0022890 inorganic cation transmembrane transporter activity
2.38 1.16e-02 GO:0005099 Ras GTPase activator activity
2.02 1.16e-02 GO:0005085 guanyl-nucleotide exchange factor activity
1.52 1.26e-02 GO:0008324 cation transmembrane transporter activity
1.65 2.24e-02 GO:0008047 enzyme activator activity
2.26 2.34e-02 GO:0030165 PDZ domain binding
1.64 3.08e-02 GO:0022804 active transmembrane transporter activity