• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: ZIC1..3.p2

Z-value: 2.335

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_-_101327849	59.890	NM_018884	Pdzrn3	PDZ domain containing RING finger 3
chr9_+_50560862	52.242	NM_009964	Cryab	crystallin, alpha B
chr9_+_50561381	51.178		Cryab	crystallin, alpha B
chr9_+_50561315	47.380		Cryab	crystallin, alpha B
chrX_-_91787338	42.442		Maged1	melanoma antigen, family D, 1
chrX_-_91787317	42.126		Maged1	melanoma antigen, family D, 1
chr7_+_138122822	40.843		Htra1	HtrA serine peptidase 1
chrX_-_91787353	40.394		Maged1	melanoma antigen, family D, 1
chr9_+_50561092	40.116		Cryab	crystallin, alpha B
chr9_+_50561121	39.531		Cryab	crystallin, alpha B
chrX_-_91787351	38.891		Maged1	melanoma antigen, family D, 1
chrX_-_91787372	37.669	NM_019791	Maged1	melanoma antigen, family D, 1
chr19_-_38199737	34.337	NM_001159487	Rbp4	retinol binding protein 4, plasma
chr7_+_106416854	33.756	NM_001043355	Mtap6	microtubule-associated protein 6
chr11_-_116515361	31.104		Cygb	cytoglobin
chr12_+_110779204	29.191		Meg3	maternally expressed 3
chr1_+_72871060	29.080	NM_008342	Igfbp2	insulin-like growth factor binding protein 2
chr11_+_101107635	28.566	NM_019444	Ramp2	receptor (calcitonin) activity modifying protein 2
chr19_-_38199291	28.338	NM_011255	Rbp4	retinol binding protein 4, plasma
chr11_+_101107726	27.806		Ramp2	receptor (calcitonin) activity modifying protein 2
chr12_+_30687597	27.548		Pxdn	peroxidasin homolog (Drosophila)
chr7_-_119301920	26.984		Dkk3	dickkopf homolog 3 (Xenopus laevis)
chr2_+_157385835	26.657	NM_010923 NM_180960	Nnat	neuronatin
chr5_-_24107718	26.146	NM_025891	Smarcd3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr17_+_37187550	25.851		Gabbr1	gamma-aminobutyric acid (GABA) B receptor, 1
chr16_-_85173764	25.673		App	amyloid beta (A4) precursor protein
chr8_-_37631772	25.164		Dlc1	deleted in liver cancer 1
chr4_-_70195870	24.706		Megf9	multiple EGF-like-domains 9
chr3_-_57651409	24.508		Pfn2	profilin 2
chr8_-_37631532	24.320		Dlc1	deleted in liver cancer 1
chr3_+_68298129	24.061		Schip1	schwannomin interacting protein 1
chr8_-_67171692	24.055		Cpe	carboxypeptidase E
chr16_-_85173851	23.589		App	amyloid beta (A4) precursor protein
chr15_-_75921924	22.966		Nrbp2	nuclear receptor binding protein 2
chr16_-_85173930	22.309		App	amyloid beta (A4) precursor protein
chr14_+_102129129	22.264	NM_201529	Lmo7	LIM domain only 7
chr19_-_38199267	22.177		Rbp4	retinol binding protein 4, plasma
chr16_-_85173918	22.141		App	amyloid beta (A4) precursor protein
chr12_-_112910475	21.981	NM_021273	Ckb	creatine kinase, brain
chr4_-_4065205	21.604		Penk	preproenkephalin
chr16_-_85173978	21.592		App	amyloid beta (A4) precursor protein
chr16_-_85173944	21.371	NM_001198823 NM_001198824 NM_001198825 NM_001198826 NM_007471	App	amyloid beta (A4) precursor protein
chr15_-_98783909	21.133	NM_011653	Tuba1a	tubulin, alpha 1A
chr18_-_60760086	20.634		Synpo	synaptopodin
chr18_-_60760126	20.589		Synpo	synaptopodin
chr1_+_45402907	20.178		Col3a1	collagen, type III, alpha 1
chr12_+_32008372	19.945		Lamb1	laminin B1
chr18_-_52688607	19.797		Lox	lysyl oxidase
chr4_-_4065585	19.790	NM_001002927	Penk	preproenkephalin
chr5_+_136363810	19.299		Hspb1	heat shock protein 1
chr13_-_100286521	19.041	NM_008634	Mtap1b	microtubule-associated protein 1B
chr16_-_85803359	18.539	NM_009621	Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
chr11_+_78002569	18.212		Rab34	RAB34, member of RAS oncogene family
chr9_-_66881744	18.138		Tpm1	tropomyosin 1, alpha
chr5_+_91946651	18.127	NM_145562	Parm1	prostate androgen-regulated mucin-like protein 1
chr7_-_106501620	17.791		Serpinh1	serine (or cysteine) peptidase inhibitor, clade H, member 1
chr5_+_89316245	17.638	NM_001136260 NM_001197147 NM_018760	Slc4a4	solute carrier family 4 (anion exchanger), member 4
chr7_-_91754314	17.578		Fah	fumarylacetoacetate hydrolase
chr7_-_106501642	17.501	NM_001111043 NM_001111044 NM_009825	Serpinh1	serine (or cysteine) peptidase inhibitor, clade H, member 1
chr13_-_100286446	17.088		Mtap1b	microtubule-associated protein 1B
chr2_+_117937623	16.797	NM_011580	Thbs1	thrombospondin 1
chr7_-_108025317	16.680		Arhgef17	Rho guanine nucleotide exchange factor (GEF) 17
chr16_-_85803343	16.631		Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
chr5_+_143734622	16.625
chr15_+_78258993	16.531	NM_001081367	Kctd17	potassium channel tetramerisation domain containing 17
chr3_+_90345082	16.510	NM_026416	S100a16	S100 calcium binding protein A16
chr5_-_5514787	16.403	NM_001193660 NM_001193659 NM_001193661 NM_022890	Cldn12	claudin 12
chr11_-_121249511	16.299	NM_139147	Rab40b	Rab40b, member RAS oncogene family
chr12_+_45429966	16.135		Nrcam	neuron-glia-CAM-related cell adhesion molecule
chr16_+_91270319	16.066		Olig1	oligodendrocyte transcription factor 1
chr14_+_14117313	16.054		Synpr	synaptoporin
chr19_-_34329804	15.993	NM_007392	Acta2	actin, alpha 2, smooth muscle, aorta
chr7_-_149838254	15.856		Igf2	insulin-like growth factor 2
chr5_-_17866110	15.825	NM_010305	Gnai1	guanine nucleotide binding protein (G protein), alpha inhibiting 1
chr4_-_142889372	15.609	NM_010329	Pdpn	podoplanin
chr16_+_18777032	15.519		Cldn5	claudin 5
chr19_+_6384413	15.479	NM_011224	Pygm	muscle glycogen phosphorylase
chr8_-_67171805	15.270	NM_013494	Cpe	carboxypeptidase E
chr11_+_94808758	15.207		Col1a1	collagen, type I, alpha 1
chr14_+_14117292	14.979	NM_028052	Synpr	synaptoporin
chr16_-_46496886	14.947	NM_021495 NM_021496 NM_021497	Pvrl3	poliovirus receptor-related 3
chr7_+_19661548	14.902	NM_010058	Dmwd	dystrophia myotonica-containing WD repeat motif
chr19_-_38199112	14.891		Rbp4	retinol binding protein 4, plasma
chr10_-_83903215	14.806	NM_001004363	Nuak1	NUAK family, SNF1-like kinase, 1
chr5_-_5514729	14.760		Cldn12	claudin 12
chr18_+_37966157	14.754		Pcdhgc3	protocadherin gamma subfamily C, 3
chr2_-_32208737	14.651	NM_010065	Dnm1	dynamin 1
chr19_-_38199036	14.355		Rbp4	retinol binding protein 4, plasma
chr12_+_45429913	14.135		Nrcam	neuron-glia-CAM-related cell adhesion molecule
chr8_-_42127124	14.028		Mtus1	mitochondrial tumor suppressor 1
chr11_-_116515602	14.009	NM_030206	Cygb	cytoglobin
chr7_-_20284500	13.910	NM_009696	Apoe	apolipoprotein E
chrX_-_45245608	13.641	NM_053123	Smarca1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr18_+_37966017	13.549	NM_033581	Pcdhgc3	protocadherin gamma subfamily C, 3
chr10_+_85763294	13.524		Timp3	tissue inhibitor of metalloproteinase 3
chr8_+_46744023	13.175		Sorbs2	sorbin and SH3 domain containing 2
chr16_+_18776936	13.149	NM_013805	Cldn5	claudin 5
chr9_+_43875175	13.040		Usp2	ubiquitin specific peptidase 2
chr19_+_5474801	12.978		Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2
chr19_+_5474686	12.897	NM_021474 NM_001164352	Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2
chr14_+_84843366	12.854	NM_001013753	Pcdh17	protocadherin 17
chr8_+_71404452	12.831	NM_008509	Lpl	lipoprotein lipase
chr6_+_124959207	12.808		Zfp384	zinc finger protein 384
chr17_+_37187984	12.708		Gabbr1	gamma-aminobutyric acid (GABA) B receptor, 1
chr16_+_18776955	12.686		Cldn5	claudin 5
chr16_+_91270009	12.652	NM_016968	Olig1	oligodendrocyte transcription factor 1
chr7_-_118923483	12.629	NM_173739	Galntl4	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 4
chr3_+_90341208	12.513		S100a16	S100 calcium binding protein A16
chr10_-_127058163	12.391		Lrp1	low density lipoprotein receptor-related protein 1
chr5_+_104888468	12.243	NM_008861	Pkd2	polycystic kidney disease 2
chr1_-_155033576	12.191	NM_008485	Lamc2	laminin, gamma 2
chr19_+_5475020	12.185		Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2
chr6_-_124586102	12.169	NM_173864	Gm5077	predicted gene 5077
chrX_-_22942176	12.161	NM_026167	Klhl13	kelch-like 13 (Drosophila)
chr8_+_56040193	11.971		Gpm6a	glycoprotein m6a
chr13_-_115248924	11.846	NM_008046	Fst	follistatin
chr7_-_106501584	11.840		Serpinh1	serine (or cysteine) peptidase inhibitor, clade H, member 1
chr4_-_61869579	11.821	NM_009554	Zfp37	zinc finger protein 37
chr19_+_4711207	11.751		Spnb3	spectrin beta 3
chr12_+_110691637	11.739	NM_001190703 NM_001190704 NM_001190705 NM_010052	Dlk1	delta-like 1 homolog (Drosophila)
chr12_+_110691856	11.708		Dlk1	delta-like 1 homolog (Drosophila)
chr18_+_58038278	11.699	NM_009194	Slc12a2	solute carrier family 12, member 2
chr2_+_109757803	11.565	NM_172671	Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4
chr9_+_43851466	11.549	NM_009382	Thy1	thymus cell antigen 1, theta
chr7_+_135390325	11.514	NM_009365	Tgfb1i1	transforming growth factor beta 1 induced transcript 1
chr3_+_62142698	11.492	NM_001081295	Arhgef26	Rho guanine nucleotide exchange factor (GEF) 26
chr18_+_82754377	11.446		Mbp	myelin basic protein
chr9_-_91259829	11.425		Zic1	zinc finger protein of the cerebellum 1
chr9_+_43875103	11.298	NM_198092	Usp2	ubiquitin specific peptidase 2
chr4_+_54960816	11.265	NM_172867	Zfp462	zinc finger protein 462
chr5_+_75552144	11.117	NM_001083316	Pdgfra	platelet derived growth factor receptor, alpha polypeptide
chr7_+_19661811	11.079		Dmwd	dystrophia myotonica-containing WD repeat motif
chr4_-_142889312	11.013		Pdpn	podoplanin
chr4_+_137476662	10.974		Ece1	endothelin converting enzyme 1
chr15_-_98781060	10.913		Tuba1a	tubulin, alpha 1A
chr1_-_174128558	10.878		Pea15a	phosphoprotein enriched in astrocytes 15A
chr1_+_181598319	10.788	NM_178653	Sccpdh	saccharopine dehydrogenase (putative)
chr12_+_96930429	10.735	NM_201518	Flrt2	fibronectin leucine rich transmembrane protein 2
chr4_-_58083082	10.704		Svep1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr4_-_150482562	10.667		Camta1	calmodulin binding transcription activator 1
chr6_-_142650737	10.662	NM_001044720 NM_011511 NM_021041 NM_021042	Abcc9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr4_-_61869471	10.646		Zfp37	zinc finger protein 37
chr4_-_68615382	10.553	NM_019967	Dbc1	deleted in bladder cancer 1 (human)
chr4_-_68615283	10.551		Dbc1	deleted in bladder cancer 1 (human)
chr5_+_72091188	10.547	NM_008069	Gabrb1	gamma-aminobutyric acid (GABA) A receptor, subunit beta 1
chr7_+_25266986	10.537	NM_153112	Cadm4	cell adhesion molecule 4
chr5_-_148537561	10.485	NM_010228	Flt1	FMS-like tyrosine kinase 1
chr4_-_58566053	10.474	NM_172989	Lpar1	lysophosphatidic acid receptor 1
chr7_+_135390456	10.342		Tgfb1i1	transforming growth factor beta 1 induced transcript 1
chr6_+_43215604	10.244	NM_133674	Arhgef5	Rho guanine nucleotide exchange factor (GEF) 5
chr2_+_35137898	10.164	NM_146120	Gsn	gelsolin
chr12_+_45429857	10.146	NM_001146031 NM_176930	Nrcam	neuron-glia-CAM-related cell adhesion molecule
chr8_-_42127242	10.141	NM_001005865	Mtus1	mitochondrial tumor suppressor 1
chr9_-_83040061	10.058	NM_026122 NM_175074	Hmgn3	high mobility group nucleosomal binding domain 3
chr3_-_117063090	9.992		D3Bwg0562e	DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed
chr7_-_91754397	9.921	NM_010176	Fah	fumarylacetoacetate hydrolase
chr4_-_61869287	9.848		Zfp37	zinc finger protein 37
chr9_-_50560397	9.810	NM_001164708 NM_024441	Hspb2	heat shock protein 2
chr17_+_37182910	9.791	NM_019439	Gabbr1	gamma-aminobutyric acid (GABA) B receptor, 1
chr1_+_60466462	9.776	NM_001198570 NM_001198571 NM_198127	Abi2	abl-interactor 2
chr17_-_7997838	9.773	NM_001081416	Fndc1	fibronectin type III domain containing 1
chr11_-_32122259	9.764	NM_010117	Rhbdf1	rhomboid family 1 (Drosophila)
chr11_+_61298923	9.753	NM_029568	Mfap4	microfibrillar-associated protein 4
chr4_+_124336307	9.746		Pou3f1	POU domain, class 3, transcription factor 1
chr11_-_32122236	9.735		Rhbdf1	rhomboid family 1 (Drosophila)
chr17_+_35272145	9.636	NM_057171	Bag6	BCL2-associated athanogene 6
chr5_-_133018212	9.567	NM_177047	Auts2	autism susceptibility candidate 2
chr9_+_21903696	9.540	NM_009922	Cnn1	calponin 1
chr8_+_129587894	9.493	NM_001122850 NM_033620	Pard3	par-3 (partitioning defective 3) homolog (C. elegans)
chr15_+_78858872	9.417		H1f0	H1 histone family, member 0
chr1_+_60466568	9.415		Abi2	abl-interactor 2
chr9_+_60642248	9.382	NM_028283	Uaca	uveal autoantigen with coiled-coil domains and ankyrin repeats
chr2_-_144353133	9.369	NM_172859	6330439K17Rik	RIKEN cDNA 6330439K17 gene
chr6_-_142456402	9.367	NM_008492	Ldhb	lactate dehydrogenase B
chr12_-_51750204	9.343	NM_008858	Prkd1	protein kinase D1
chr7_-_82453216	9.337	NM_001109753	Sv2b	synaptic vesicle glycoprotein 2 b
chr6_+_30688050	9.334	NM_008590	Mest	mesoderm specific transcript
chr6_+_115189004	9.187		Syn2	synapsin II
chr1_+_60466499	9.147		Abi2	abl-interactor 2
chr15_+_78858900	9.105		H1f0	H1 histone family, member 0
chr14_-_22806999	9.095		Zfp503	zinc finger protein 503
chr13_-_78338131	9.092	NM_010151	Nr2f1	nuclear receptor subfamily 2, group F, member 1
chr3_+_98186380	9.060	NM_172863	Zfp697	zinc finger protein 697
chr14_-_22806631	9.037		Zfp503	zinc finger protein 503
chr11_+_34934956	9.021	NM_011412	Slit3	slit homolog 3 (Drosophila)
chr1_+_137625754	9.016	NM_007791	Csrp1	cysteine and glycine-rich protein 1
chr11_-_41995688	9.003		Gabra1	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr1_+_164569335	8.958		Myoc	myocilin
chr7_-_149843316	8.922	NM_001122737	Igf2	insulin-like growth factor 2
chr1_-_170361525	8.897		Pbx1	pre B-cell leukemia transcription factor 1
chr9_-_49311823	8.836		Ncam1	neural cell adhesion molecule 1
chr6_+_138089041	8.810	NM_019946	Mgst1	microsomal glutathione S-transferase 1
chr1_+_75356906	8.781		Des	desmin
chr9_-_54509453	8.756		Acsbg1	acyl-CoA synthetase bubblegum family member 1
chr8_+_56040211	8.741		Gpm6a	glycoprotein m6a
chr11_-_35793951	8.710		Wwc1	WW, C2 and coiled-coil domain containing 1
chr12_+_77505356	8.664	NM_008301	Hspa2	heat shock protein 2
chr6_-_118429262	8.658		Zfp9	zinc finger protein 9
chr15_+_78858886	8.618		H1f0	H1 histone family, member 0
chr13_-_55614750	8.569	NM_001114087 NM_001114088 NM_026131	Pdlim7	PDZ and LIM domain 7

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.71	1.32e-16	GO:0048731	system development
1.64	1.30e-15	GO:0048856	anatomical structure development
1.56	7.89e-15	GO:0032502	developmental process
1.57	8.14e-14	GO:0007275	multicellular organismal development
1.54	1.22e-13	GO:0051179	localization
1.59	3.94e-13	GO:0051234	establishment of localization
1.57	4.38e-13	GO:0016043	cellular component organization
1.59	8.98e-13	GO:0006810	transport
1.83	2.48e-11	GO:0009653	anatomical structure morphogenesis
1.51	5.14e-11	GO:0071840	cellular component organization or biogenesis
1.86	3.04e-10	GO:0007399	nervous system development
1.52	3.08e-10	GO:0048518	positive regulation of biological process
1.67	3.81e-10	GO:0065008	regulation of biological quality
2.04	5.71e-10	GO:0051128	regulation of cellular component organization
1.53	1.28e-09	GO:0048522	positive regulation of cellular process
1.88	1.79e-09	GO:0010646	regulation of cell communication
1.85	1.37e-08	GO:0050793	regulation of developmental process
1.70	1.87e-08	GO:0023051	regulation of signaling
1.57	1.87e-08	GO:0048869	cellular developmental process
2.13	2.01e-08	GO:0007155	cell adhesion
2.11	3.21e-08	GO:0022610	biological adhesion
1.57	6.24e-08	GO:0030154	cell differentiation
1.60	6.30e-08	GO:0048513	organ development
1.54	8.36e-08	GO:0071842	cellular component organization at cellular level
1.66	1.07e-07	GO:0051239	regulation of multicellular organismal process
1.81	2.11e-07	GO:0051641	cellular localization
1.88	2.48e-07	GO:2000026	regulation of multicellular organismal development
1.94	2.86e-07	GO:0048699	generation of neurons
1.89	5.40e-07	GO:0022008	neurogenesis
1.87	6.95e-07	GO:0048468	cell development
1.50	7.96e-07	GO:0048523	negative regulation of cellular process
1.47	1.09e-06	GO:0048519	negative regulation of biological process
2.42	1.47e-06	GO:0019226	transmission of nerve impulse
2.42	1.47e-06	GO:0035637	multicellular organismal signaling
1.98	1.55e-06	GO:0007154	cell communication
2.09	2.49e-06	GO:0010647	positive regulation of cell communication
1.75	3.02e-06	GO:0032879	regulation of localization
3.00	3.47e-06	GO:0043062	extracellular structure organization
1.68	3.68e-06	GO:0033036	macromolecule localization
2.72	4.12e-06	GO:0051129	negative regulation of cellular component organization
2.15	5.44e-06	GO:0034613	cellular protein localization
1.47	5.58e-06	GO:0071841	cellular component organization or biogenesis at cellular level
2.14	7.23e-06	GO:0070727	cellular macromolecule localization
2.05	7.66e-06	GO:0023056	positive regulation of signaling
1.81	8.11e-06	GO:0051649	establishment of localization in cell
2.17	1.15e-05	GO:0016044	cellular membrane organization
2.16	1.39e-05	GO:0061024	membrane organization
1.72	1.40e-05	GO:0008104	protein localization
2.02	1.63e-05	GO:0030182	neuron differentiation
1.82	2.52e-05	GO:0045595	regulation of cell differentiation
1.76	2.88e-05	GO:0009888	tissue development
2.67	4.02e-05	GO:0044087	regulation of cellular component biogenesis
2.25	4.12e-05	GO:0022603	regulation of anatomical structure morphogenesis
2.04	4.82e-05	GO:0009967	positive regulation of signal transduction
2.00	5.50e-05	GO:0072358	cardiovascular system development
2.00	5.50e-05	GO:0072359	circulatory system development
1.62	6.21e-05	GO:0009966	regulation of signal transduction
2.14	6.30e-05	GO:0060284	regulation of cell development
2.04	6.66e-05	GO:0050801	ion homeostasis
1.17	7.31e-05	GO:0065007	biological regulation
1.77	8.31e-05	GO:0045184	establishment of protein localization
1.88	1.15e-04	GO:0009887	organ morphogenesis
2.24	1.24e-04	GO:0035295	tube development
2.41	1.28e-04	GO:0007268	synaptic transmission
1.95	1.57e-04	GO:0051094	positive regulation of developmental process
2.09	1.59e-04	GO:0007267	cell-cell signaling
1.88	1.59e-04	GO:0046907	intracellular transport
5.49	1.80e-04	GO:0045669	positive regulation of osteoblast differentiation
1.76	2.14e-04	GO:0015031	protein transport
1.29	2.28e-04	GO:0019222	regulation of metabolic process
2.24	3.03e-04	GO:0000904	cell morphogenesis involved in differentiation
2.03	3.58e-04	GO:0006873	cellular ion homeostasis
2.43	3.83e-04	GO:0030029	actin filament-based process
2.11	3.92e-04	GO:0051960	regulation of nervous system development
2.01	3.95e-04	GO:0055082	cellular chemical homeostasis
2.57	4.13e-04	GO:0031344	regulation of cell projection organization
3.94	4.14e-04	GO:0045667	regulation of osteoblast differentiation
1.84	4.73e-04	GO:0048878	chemical homeostasis
2.18	5.38e-04	GO:0001944	vasculature development
1.63	5.48e-04	GO:0010941	regulation of cell death
2.03	5.74e-04	GO:0048666	neuron development
2.46	5.84e-04	GO:0030036	actin cytoskeleton organization
2.17	6.54e-04	GO:0031175	neuron projection development
1.11	7.14e-04	GO:0009987	cellular process
1.99	8.84e-04	GO:0000902	cell morphogenesis
2.66	8.88e-04	GO:0042391	regulation of membrane potential
2.14	9.59e-04	GO:0006886	intracellular protein transport
1.88	9.86e-04	GO:0019725	cellular homeostasis
2.45	1.28e-03	GO:0051969	regulation of transmission of nerve impulse
2.38	1.34e-03	GO:0031644	regulation of neurological system process
3.67	1.40e-03	GO:0010810	regulation of cell-substrate adhesion
2.24	1.44e-03	GO:0001501	skeletal system development
1.61	1.52e-03	GO:0043067	regulation of programmed cell death
1.92	1.54e-03	GO:0032989	cellular component morphogenesis
2.23	1.59e-03	GO:0051347	positive regulation of transferase activity
1.68	1.65e-03	GO:0009790	embryo development
2.18	1.66e-03	GO:0001568	blood vessel development
2.50	1.72e-03	GO:0050804	regulation of synaptic transmission
2.91	1.79e-03	GO:0030324	lung development
1.59	2.07e-03	GO:0035556	intracellular signal transduction
1.48	2.40e-03	GO:0065009	regulation of molecular function
2.87	2.47e-03	GO:0030323	respiratory tube development
2.11	2.68e-03	GO:0040012	regulation of locomotion
1.86	2.91e-03	GO:0009792	embryo development ending in birth or egg hatching
1.78	2.98e-03	GO:0016192	vesicle-mediated transport
1.28	3.14e-03	GO:0080090	regulation of primary metabolic process
1.86	3.68e-03	GO:0043009	chordate embryonic development
2.21	3.79e-03	GO:0033674	positive regulation of kinase activity
1.99	3.93e-03	GO:0090066	regulation of anatomical structure size
1.28	4.23e-03	GO:0031323	regulation of cellular metabolic process
2.14	4.72e-03	GO:0030334	regulation of cell migration
1.59	4.75e-03	GO:0042981	regulation of apoptosis
1.15	5.01e-03	GO:0050789	regulation of biological process
1.97	5.45e-03	GO:0051093	negative regulation of developmental process
2.05	5.49e-03	GO:0050767	regulation of neurogenesis
2.24	6.16e-03	GO:0048514	blood vessel morphogenesis
2.21	6.65e-03	GO:0045860	positive regulation of protein kinase activity
2.21	6.65e-03	GO:0048812	neuron projection morphogenesis
2.66	6.81e-03	GO:0060541	respiratory system development
2.11	6.86e-03	GO:2000145	regulation of cell motility
1.43	7.86e-03	GO:0048583	regulation of response to stimulus
4.47	8.01e-03	GO:0043242	negative regulation of protein complex disassembly
3.58	8.08e-03	GO:0051494	negative regulation of cytoskeleton organization
2.49	8.30e-03	GO:0010975	regulation of neuron projection development
2.04	9.02e-03	GO:0032535	regulation of cellular component size
1.87	9.72e-03	GO:0007010	cytoskeleton organization
2.01	9.99e-03	GO:0007420	brain development
2.04	1.05e-02	GO:0051270	regulation of cellular component movement
2.28	1.10e-02	GO:0007409	axonogenesis
1.65	1.12e-02	GO:0051049	regulation of transport
1.99	1.28e-02	GO:0051130	positive regulation of cellular component organization
1.94	1.30e-02	GO:0048729	tissue morphogenesis
2.99	1.32e-02	GO:0040013	negative regulation of locomotion
1.89	1.36e-02	GO:0051338	regulation of transferase activity
2.19	1.43e-02	GO:0048667	cell morphogenesis involved in neuron differentiation
3.78	1.49e-02	GO:0050808	synapse organization
1.93	1.52e-02	GO:0045859	regulation of protein kinase activity
3.15	1.65e-02	GO:0030336	negative regulation of cell migration
3.15	1.65e-02	GO:2000146	negative regulation of cell motility
2.11	1.67e-02	GO:0045664	regulation of neuron differentiation
3.95	1.73e-02	GO:0043244	regulation of protein complex disassembly
1.90	1.74e-02	GO:0043549	regulation of kinase activity
2.44	1.89e-02	GO:0006605	protein targeting
4.17	1.93e-02	GO:0007269	neurotransmitter secretion
1.15	2.24e-02	GO:0050794	regulation of cellular process
2.02	2.37e-02	GO:0048858	cell projection morphogenesis
1.26	2.42e-02	GO:0060255	regulation of macromolecule metabolic process
2.80	2.53e-02	GO:0030278	regulation of ossification
2.32	2.72e-02	GO:0030155	regulation of cell adhesion
2.53	2.76e-02	GO:0010769	regulation of cell morphogenesis involved in differentiation
2.53	2.76e-02	GO:0022604	regulation of cell morphogenesis
2.71	2.86e-02	GO:0030198	extracellular matrix organization
1.60	3.05e-02	GO:0044093	positive regulation of molecular function
2.05	3.13e-02	GO:0002009	morphogenesis of an epithelium
1.78	3.17e-02	GO:0030030	cell projection organization
1.86	3.42e-02	GO:0045597	positive regulation of cell differentiation
1.75	3.43e-02	GO:0048646	anatomical structure formation involved in morphogenesis
1.98	3.89e-02	GO:0032990	cell part morphogenesis
6.27	3.96e-02	GO:0010596	negative regulation of endothelial cell migration
1.55	4.27e-02	GO:0042592	homeostatic process
1.70	4.67e-02	GO:0001932	regulation of protein phosphorylation
2.95	4.68e-02	GO:0006836	neurotransmitter transport
2.95	4.68e-02	GO:0051271	negative regulation of cellular component movement
2.04	4.72e-02	GO:0007264	small GTPase mediated signal transduction

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.33	3.11e-21	GO:0005737	cytoplasm
2.77	2.78e-20	GO:0043005	neuron projection
2.15	3.04e-18	GO:0042995	cell projection
1.22	1.15e-17	GO:0005622	intracellular
1.53	2.79e-17	GO:0071944	cell periphery
2.52	5.61e-17	GO:0030054	cell junction
2.75	7.68e-17	GO:0045202	synapse
1.22	9.77e-17	GO:0044424	intracellular part
1.81	2.55e-16	GO:0044459	plasma membrane part
1.52	5.25e-16	GO:0005886	plasma membrane
2.02	5.92e-16	GO:0000267	cell fraction
3.17	3.01e-14	GO:0030425	dendrite
2.10	4.18e-14	GO:0005626	insoluble fraction
2.92	1.56e-13	GO:0044456	synapse part
1.12	3.51e-13	GO:0005623	cell
1.12	3.51e-13	GO:0044464	cell part
2.09	5.41e-13	GO:0005624	membrane fraction
1.35	1.03e-12	GO:0044444	cytoplasmic part
1.23	1.60e-12	GO:0043229	intracellular organelle
1.23	2.26e-12	GO:0043226	organelle
2.55	2.77e-11	GO:0044463	cell projection part
2.67	1.50e-10	GO:0044297	cell body
2.67	5.26e-10	GO:0043025	neuronal cell body
2.04	2.42e-09	GO:0031410	cytoplasmic vesicle
1.97	8.01e-09	GO:0031982	vesicle
1.64	5.50e-08	GO:0005856	cytoskeleton
1.20	1.07e-07	GO:0016020	membrane
2.11	2.37e-07	GO:0016023	cytoplasmic membrane-bounded vesicle
3.00	5.22e-07	GO:0031252	cell leading edge
1.19	7.51e-07	GO:0043231	intracellular membrane-bounded organelle
1.19	7.94e-07	GO:0043227	membrane-bounded organelle
2.55	9.94e-07	GO:0030424	axon
2.02	1.20e-06	GO:0031988	membrane-bounded vesicle
2.65	1.44e-06	GO:0005911	cell-cell junction
1.71	6.22e-06	GO:0005794	Golgi apparatus
2.27	8.81e-06	GO:0031012	extracellular matrix
2.34	1.76e-05	GO:0005578	proteinaceous extracellular matrix
2.81	2.28e-05	GO:0030135	coated vesicle
1.66	3.67e-05	GO:0044421	extracellular region part
3.45	4.70e-05	GO:0043296	apical junction complex
3.38	7.11e-05	GO:0016327	apicolateral plasma membrane
3.57	9.01e-05	GO:0014069	postsynaptic density
2.91	1.06e-04	GO:0019717	synaptosome
2.80	1.46e-04	GO:0030136	clathrin-coated vesicle
2.89	1.99e-04	GO:0033267	axon part
2.80	2.32e-04	GO:0070161	anchoring junction
5.46	2.52e-04	GO:0044304	main axon
2.05	3.21e-04	GO:0005625	soluble fraction
3.58	3.30e-04	GO:0044309	neuron spine
2.63	3.86e-04	GO:0045211	postsynaptic membrane
3.40	4.05e-04	GO:0005923	tight junction
3.40	4.05e-04	GO:0070160	occluding junction
2.84	4.33e-04	GO:0005912	adherens junction
3.14	5.20e-04	GO:0008021	synaptic vesicle
2.67	6.44e-04	GO:0005938	cell cortex
3.48	9.78e-04	GO:0043197	dendritic spine
4.20	1.16e-03	GO:0031256	leading edge membrane
1.57	2.03e-03	GO:0044430	cytoskeletal part
4.87	7.39e-03	GO:0030672	synaptic vesicle membrane
2.62	7.52e-03	GO:0043292	contractile fiber
2.91	8.29e-03	GO:0030017	sarcomere
2.65	9.09e-03	GO:0044420	extracellular matrix part
1.45	1.05e-02	GO:0031090	organelle membrane
2.35	1.12e-02	GO:0044433	cytoplasmic vesicle part
2.28	1.38e-02	GO:0012506	vesicle membrane
1.27	1.42e-02	GO:0043234	protein complex
1.55	1.55e-02	GO:0012505	endomembrane system
2.34	1.75e-02	GO:0030659	cytoplasmic vesicle membrane
2.69	1.75e-02	GO:0044449	contractile fiber part
1.96	1.77e-02	GO:0015629	actin cytoskeleton
2.60	1.90e-02	GO:0030016	myofibril
2.86	2.92e-02	GO:0044448	cell cortex part
1.89	3.03e-02	GO:0048471	perinuclear region of cytoplasm
1.20	3.08e-02	GO:0044422	organelle part
1.14	3.31e-02	GO:0044425	membrane part
2.04	3.73e-02	GO:0016323	basolateral plasma membrane
11.29	4.92e-02	GO:0008091	spectrin
1.36	4.96e-02	GO:0005829	cytosol

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.48	2.87e-25	GO:0005515	protein binding
1.24	3.98e-20	GO:0005488	binding
2.20	1.53e-08	GO:0008092	cytoskeletal protein binding
3.23	1.49e-04	GO:0019838	growth factor binding
1.84	5.73e-04	GO:0019904	protein domain specific binding
2.87	8.84e-04	GO:0005516	calmodulin binding
1.94	1.69e-03	GO:0005198	structural molecule activity
1.95	3.17e-03	GO:0032403	protein complex binding
1.98	1.11e-02	GO:0003779	actin binding
1.48	2.43e-02	GO:0005102	receptor binding
1.53	2.53e-02	GO:0019899	enzyme binding
4.41	2.93e-02	GO:0035254	glutamate receptor binding
5.38	3.42e-02	GO:0005212	structural constituent of eye lens
7.06	4.96e-02	GO:0048407	platelet-derived growth factor binding