Motif ID: ZNF143.p2

Z-value: 3.828


Transcription factors associated with ZNF143.p2:

Gene SymbolEntrez IDGene Name
Zfp143 20841 zinc finger protein 143

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp143chr7_+_1172051940.334.9e-06Click!


Activity profile for motif ZNF143.p2.

activity profile for motif ZNF143.p2


Sorted Z-values histogram for motif ZNF143.p2

Sorted Z-values for motif ZNF143.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF143.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_117710532 70.316 NM_001012273
NM_009689
 Birc5

baculoviral IAP repeat-containing 5

chr5_+_34000745 67.111 NM_001040435
 Tacc3
transforming, acidic coiled-coil containing protein 3
chr7_+_13864164 62.785 NM_010715
 Lig1
ligase I, DNA, ATP-dependent
chr18_+_34784277 44.408 NM_001166407
 Kif20a
kinesin family member 20A
chr10_-_128002934 44.133 Pa2g4
proliferation-associated 2G4
chr18_+_34784589 42.417 NM_009004
NM_001166406
 Kif20a

kinesin family member 20A

chr10_-_128003058 36.249 Pa2g4
proliferation-associated 2G4
chr10_-_128002991 35.480 Pa2g4
proliferation-associated 2G4
chr10_-_128002987 35.143 NM_011119
 Pa2g4
proliferation-associated 2G4
chr15_-_81560283 33.053 Rangap1
RAN GTPase activating protein 1
chr4_+_107040647 31.104 Tmem48
transmembrane protein 48
chr15_-_81560257 31.021 Rangap1
RAN GTPase activating protein 1
chr15_-_81560302 30.436 Rangap1
RAN GTPase activating protein 1
chr15_-_81560309 30.344 NM_001146174
NM_011241
 Rangap1

RAN GTPase activating protein 1

chr8_+_73988823 28.436 NM_053162
 Mrpl34
mitochondrial ribosomal protein L34
chr12_-_114067537 28.372 NM_028023
 Cdca4
cell division cycle associated 4
chr4_+_107040388 27.219 NM_028355
 Tmem48
transmembrane protein 48
chr4_-_86257921 27.105 NM_173400
 Haus6
HAUS augmin-like complex, subunit 6
chr9_-_34983552 26.249 NM_027030
 Dcps
decapping enzyme, scavenger
chr4_+_107040634 26.042 Tmem48
transmembrane protein 48

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 105 entries
Enrichment   P-value GO Accession GO Term
4.85 4.29e-05 GO:0006261 DNA-dependent DNA replication
4.15 3.53e-02 GO:0007051 spindle organization
3.92 1.58e-04 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
3.80 6.57e-05 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
3.75 3.54e-04 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
3.70 4.57e-04 GO:0051352 negative regulation of ligase activity
3.70 4.57e-04 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
3.70 4.57e-04 GO:0051444 negative regulation of ubiquitin-protein ligase activity
3.54 7.18e-05 GO:0006414 translational elongation
3.48 5.00e-03 GO:0022618 ribonucleoprotein complex assembly
3.43 6.29e-03 GO:0000375 RNA splicing, via transesterification reactions
3.35 6.89e-05 GO:0071156 regulation of cell cycle arrest
3.32 5.04e-04 GO:0000075 cell cycle checkpoint
3.28 1.13e-03 GO:0031397 negative regulation of protein ubiquitination
3.28 3.70e-03 GO:0051443 positive regulation of ubiquitin-protein ligase activity
3.28 1.21e-02 GO:0071826 ribonucleoprotein complex subunit organization
3.28 2.21e-02 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
3.28 2.21e-02 GO:0000398 nuclear mRNA splicing, via spliceosome
3.20 5.60e-03 GO:0051351 positive regulation of ligase activity
3.17 2.10e-03 GO:0051438 regulation of ubiquitin-protein ligase activity

Gene overrepresentation in compartment category:

Showing 1 to 20 of 50 entries
Enrichment   P-value GO Accession GO Term
3.88 6.55e-03 GO:0005643 nuclear pore
3.80 3.64e-02 GO:0000118 histone deacetylase complex
3.56 2.40e-03 GO:0000502 proteasome complex
3.12 4.56e-02 GO:0046930 pore complex
3.08 3.41e-03 GO:0016585 chromatin remodeling complex
3.05 2.28e-03 GO:0000776 kinetochore
3.04 7.53e-06 GO:0005681 spliceosomal complex
3.03 1.22e-07 GO:0005840 ribosome
2.76 8.48e-18 GO:0030529 ribonucleoprotein complex
2.72 4.01e-04 GO:0000775 chromosome, centromeric region
2.63 2.40e-02 GO:0000793 condensed chromosome
2.58 5.80e-04 GO:0005759 mitochondrial matrix
2.55 3.71e-02 GO:0044455 mitochondrial membrane part
2.44 4.83e-02 GO:0005819 spindle
2.28 2.89e-09 GO:0005694 chromosome
2.27 2.06e-08 GO:0044427 chromosomal part
2.25 1.52e-03 GO:0000785 chromatin
2.16 7.17e-03 GO:0000228 nuclear chromosome
2.10 4.58e-02 GO:0044454 nuclear chromosome part
2.04 3.03e-28 GO:0044428 nuclear part

Gene overrepresentation in function category:

Showing 1 to 20 of 20 entries
Enrichment   P-value GO Accession GO Term
2.92 3.44e-04 GO:0003735 structural constituent of ribosome
2.92 5.00e-02 GO:0008565 protein transporter activity
2.63 2.25e-02 GO:0016779 nucleotidyltransferase activity
2.18 7.94e-13 GO:0003723 RNA binding
1.71 7.17e-04 GO:0016462 pyrophosphatase activity
1.71 1.37e-03 GO:0017111 nucleoside-triphosphatase activity
1.70 8.68e-04 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.70 9.24e-04 GO:0016817 hydrolase activity, acting on acid anhydrides
1.56 5.02e-13 GO:0003676 nucleic acid binding
1.47 2.88e-07 GO:0000166 nucleotide binding
1.45 6.31e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.45 9.69e-04 GO:0005524 ATP binding
1.43 1.38e-04 GO:0017076 purine nucleotide binding
1.43 1.63e-04 GO:0032555 purine ribonucleotide binding
1.43 1.69e-04 GO:0032553 ribonucleotide binding
1.43 2.28e-03 GO:0030554 adenyl nucleotide binding
1.42 2.68e-03 GO:0032559 adenyl ribonucleotide binding
1.33 2.86e-02 GO:0003677 DNA binding
1.24 2.54e-05 GO:0003824 catalytic activity
1.20 2.05e-14 GO:0005488 binding