Motif ID: ZNF148.p2

Z-value: 1.267


Transcription factors associated with ZNF148.p2:

Gene SymbolEntrez IDGene Name
Zfp148 22661 zinc finger protein 148

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp148chr16_+_33500899-0.281.0e-04Click!


Activity profile for motif ZNF148.p2.

activity profile for motif ZNF148.p2


Sorted Z-values histogram for motif ZNF148.p2

Sorted Z-values for motif ZNF148.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF148.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_117127516 11.867 NM_001113487
Sept9
septin 9
chr5_-_98459943 11.307 NM_133738
Antxr2
anthrax toxin receptor 2
chr11_+_117127762 11.135 Sept9
septin 9
chr6_-_72908352 10.447 NM_025284
Tmsb10
thymosin, beta 10
chr6_-_72908018 10.341 NM_001039392
Tmsb10
thymosin, beta 10
chr8_-_124948837 10.139


chr9_-_65427840 9.826 NM_153119
Plekho2
pleckstrin homology domain containing, family O member 2
chr19_-_21547035 9.069 Gda
guanine deaminase
chr19_-_21547072 8.831 NM_010266
Gda
guanine deaminase
chr7_+_89003886 8.596 NM_145375
Tm6sf1
transmembrane 6 superfamily member 1
chr7_-_71083734 8.566 NM_021366
Klf13
Kruppel-like factor 13
chr19_-_3907120 8.162 NM_001136091
Tcirg1
T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3
chr19_-_3907038 7.988 Tcirg1
T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3
chr16_-_32165509 7.424 NM_146069
Lrrc33
leucine rich repeat containing 33
chr1_-_51535232 7.345 NM_028696
Obfc2a
oligonucleotide/oligosaccharide-binding fold containing 2A
chr19_-_3906982 7.101 NM_001167784
Tcirg1
T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3
chr2_+_167514414 6.985 NM_009883
Cebpb
CCAAT/enhancer binding protein (C/EBP), beta
chr6_+_72499398 6.647 NM_001042534
Capg
capping protein (actin filament), gelsolin-like
chr10_-_12684064 6.571 NM_001163590
NM_001163591
NM_029075
Stx11


syntaxin 11


chr6_-_72908741 6.565 NM_001190327
Tmsb10
thymosin, beta 10
chr7_+_26471968 6.352 NM_011577
Tgfb1
transforming growth factor, beta 1
chr6_+_113328105 6.245 NM_001170485
NM_001170486
NM_026552
Arpc4


actin related protein 2/3 complex, subunit 4


chrX_+_93291377 6.109 NM_010833
Msn
moesin
chr6_-_125444722 6.109 NM_007657
Cd9
CD9 antigen
chr7_-_31827099 6.097 NM_008761
Fxyd5
FXYD domain-containing ion transport regulator 5
chr5_+_34868420 6.096 NM_011893
Sh3bp2
SH3-domain binding protein 2
chr10_+_19311761 5.995 NM_010511
Ifngr1
interferon gamma receptor 1
chr11_+_117710532 5.909 NM_001012273
NM_009689
Birc5

baculoviral IAP repeat-containing 5

chr2_-_166539223 5.850 Prex1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chrX_+_70962097 5.700 Abcd1
ATP-binding cassette, sub-family D (ALD), member 1
chr9_-_107537459 5.662


chr6_-_86743518 5.617 NM_013471
Anxa4
annexin A4
chr5_+_65194627 5.603 Klf3
Kruppel-like factor 3 (basic)
chr7_-_31826775 5.542 NM_001111073
Fxyd5
FXYD domain-containing ion transport regulator 5
chr5_+_65194784 5.478 Klf3
Kruppel-like factor 3 (basic)
chr9_+_21330620 5.465 NM_001198794
NM_206536
AB124611

cDNA sequence AB124611

chr4_-_133443662 5.406 NM_009097
Rps6ka1
ribosomal protein S6 kinase polypeptide 1
chr7_+_25155415 5.402 Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr12_+_114390258 5.350 Crip1
cysteine-rich protein 1 (intestinal)
chr5_-_123582394 5.345 Rhof
ras homolog gene family, member f
chr16_+_15887375 5.242 NM_007679
Cebpd
CCAAT/enhancer binding protein (C/EBP), delta
chr11_+_105945892 5.175 Map3k3
mitogen-activated protein kinase kinase kinase 3
chr1_-_133141708 5.031 NM_018750
Rassf5
Ras association (RalGDS/AF-6) domain family member 5
chr17_+_31701700 5.009 NM_016670
Pknox1
Pbx/knotted 1 homeobox
chr3_+_145813230 5.007 Mcoln2
mucolipin 2
chr5_+_34892224 4.960 NM_001145859
NM_001136088
Sh3bp2

SH3-domain binding protein 2

chr14_-_121778399 4.944 NM_145465
Stk24
serine/threonine kinase 24 (STE20 homolog, yeast)
chr1_+_34529567 4.909 Ptpn18
protein tyrosine phosphatase, non-receptor type 18
chrX_-_72376117 4.836 NM_008621
Mpp1
membrane protein, palmitoylated
chr5_+_65194749 4.801 NM_008453
Klf3
Kruppel-like factor 3 (basic)
chr3_+_145813137 4.737 NM_001005846
Mcoln2
mucolipin 2
chr15_+_81977766 4.731 Srebf2
sterol regulatory element binding factor 2
chr10_-_12683885 4.712 Stx11
syntaxin 11
chr17_-_34324234 4.689 NM_013585
Psmb9
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
chr4_-_147525786 4.651 Fbxo6
F-box protein 6
chr6_-_39067918 4.624 Parp12
poly (ADP-ribose) polymerase family, member 12
chr5_-_98459488 4.620 Antxr2
anthrax toxin receptor 2
chr4_+_47104780 4.604 NM_172693
Galnt12
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12
chr15_-_102062331 4.598 NM_013566
Itgb7
integrin beta 7
chr17_+_35187325 4.556 Clic1
chloride intracellular channel 1
chr19_+_46380107 4.502 NM_019408
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100
chr17_+_35187185 4.484 NM_033444
Clic1
chloride intracellular channel 1
chr2_-_157030236 4.472 NM_001139516
NM_011249
Rbl1

retinoblastoma-like 1 (p107)

chr2_-_26883441 4.423 NM_001177627
NM_172659
Slc2a6

solute carrier family 2 (facilitated glucose transporter), member 6

chr2_-_75542552 4.374 NM_010902
Nfe2l2
nuclear factor, erythroid derived 2, like 2
chr2_-_163575826 4.353 NM_007398
Ada
adenosine deaminase
chr11_-_106021399 4.321 NM_172397
Limd2
LIM domain containing 2
chr8_-_86265035 4.319 NM_001163029
NM_001163030
NM_001163031
NM_011925
Cd97



CD97 antigen



chr7_+_25155279 4.278 NM_001163510
NM_008433
Kcnn4

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4

chr5_-_115750913 4.278 Dynll1
dynein light chain LC8-type 1
chr9_-_7872821 4.239 Birc3
baculoviral IAP repeat-containing 3
chr7_+_104230260 4.190 NM_001162477
NM_010248
Gab2

growth factor receptor bound protein 2-associated protein 2

chr6_+_113588460 4.139 NM_001113553
NM_172161
Irak2

interleukin-1 receptor-associated kinase 2

chr19_-_18706239 4.113 NM_017375
Ostf1
osteoclast stimulating factor 1
chr5_-_114358647 4.109 NM_011779
Coro1c
coronin, actin binding protein 1C
chr17_+_50648736 4.104 NM_013880
Plcl2
phospholipase C-like 2
chr5_-_122286849 4.089 Sh2b3
SH2B adaptor protein 3
chr1_+_154613763 4.050 Arpc5
actin related protein 2/3 complex, subunit 5
chr3_-_106350628 4.031 NM_133869
Cept1
choline/ethanolaminephosphotransferase 1
chrX_+_156065141 3.958 NM_001135727
Sh3kbp1
SH3-domain kinase binding protein 1
chr2_+_118727248 3.936 NM_001045523
Bahd1
bromo adjacent homology domain containing 1
chr11_+_105946215 3.935 NM_011947
Map3k3
mitogen-activated protein kinase kinase kinase 3
chr2_+_167514460 3.922 Cebpb
CCAAT/enhancer binding protein (C/EBP), beta
chr10_+_81022304 3.873 NM_010347
Aes
amino-terminal enhancer of split
chr5_-_115750940 3.869 Dynll1
dynein light chain LC8-type 1
chr16_+_23224889 3.850 St6gal1
beta galactoside alpha 2,6 sialyltransferase 1
chr2_-_73367455 3.842 NM_153138
Wipf1
WAS/WASL interacting protein family, member 1
chr7_+_90780446 3.802 NM_023377
Stard5
StAR-related lipid transfer (START) domain containing 5
chr17_+_27693821 3.751 Hmga1
high mobility group AT-hook 1
chr6_+_108778985 3.719 Edem1
ER degradation enhancer, mannosidase alpha-like 1
chrX_+_70962057 3.719 Abcd1
ATP-binding cassette, sub-family D (ALD), member 1
chr8_+_90806890 3.680 NM_001109756
Adcy7
adenylate cyclase 7
chr11_+_11586215 3.668 NM_001025597
NM_009578
Ikzf1

IKAROS family zinc finger 1

chr4_+_59202307 3.579 Ugcg
UDP-glucose ceramide glucosyltransferase
chr10_+_79317316 3.572 NM_001077363
NM_008956
Ptbp1

polypyrimidine tract binding protein 1

chr7_-_134169938 3.560 NM_010772
Maz
MYC-associated zinc finger protein (purine-binding transcription factor)
chr5_-_141306258 3.551 NM_010302
Gna12
guanine nucleotide binding protein, alpha 12
chr4_+_43970559 3.539 NM_027450
Glipr2
GLI pathogenesis-related 2
chr8_+_34763709 3.514 NM_010344
Gsr
glutathione reductase
chr19_+_37509290 3.510 NM_008245
Hhex
hematopoietically expressed homeobox
chr2_+_35122282 3.509 Gsn
gelsolin
chr6_-_86619001 3.499 NM_010751
Mxd1
MAX dimerization protein 1
chr17_-_45736533 3.476 Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr4_+_125701902 3.431 NM_007782
Csf3r
colony stimulating factor 3 receptor (granulocyte)
chr7_-_133848235 3.428 NM_009898
Coro1a
coronin, actin binding protein 1A
chr19_+_37624879 3.409 NM_175353
Exoc6
exocyst complex component 6
chr4_-_133189327 3.396 NM_001017968
Zdhhc18
zinc finger, DHHC domain containing 18
chr11_-_115939274 3.396 NM_001009573
Unc13d
unc-13 homolog D (C. elegans)
chr10_-_60610398 3.380 NM_009163
Sgpl1
sphingosine phosphate lyase 1
chr2_-_102741782 3.378 NM_001039150
NM_001039151
NM_001177785
NM_001177786
NM_001177787
NM_009851
Cd44





CD44 antigen





chr14_-_31439299 3.365 Prkcd
protein kinase C, delta
chr17_+_64950988 3.354 NM_008549
Man2a1
mannosidase 2, alpha 1
chr19_-_7557553 3.348 Rtn3
reticulon 3
chr1_+_173319048 3.341 NM_001005508
Arhgap30
Rho GTPase activating protein 30
chr2_-_91035167 3.321 Nr1h3
nuclear receptor subfamily 1, group H, member 3
chr7_-_29164215 3.301 NM_011756
Zfp36
zinc finger protein 36
chr4_+_59202363 3.299 NM_011673
Ugcg
UDP-glucose ceramide glucosyltransferase
chr9_-_107537602 3.279 NM_008138
Gnai2
guanine nucleotide binding protein (G protein), alpha inhibiting 2
chr11_+_75469516 3.255 NM_001080775
Myo1c
myosin IC
chr15_-_77672472 3.244 NM_022410
Myh9
myosin, heavy polypeptide 9, non-muscle
chr10_-_60610238 3.240 Sgpl1
sphingosine phosphate lyase 1
chr2_-_166888514 3.234 NM_001033196
Znfx1
zinc finger, NFX1-type containing 1
chr19_-_18706181 3.223 Ostf1
osteoclast stimulating factor 1
chr5_+_115791215 3.198 NM_026933
Triap1
TP53 regulated inhibitor of apoptosis 1
chr9_+_107885355 3.195 NM_177090
Cdh29
Uba7
cadherin-like 29
ubiquitin-like modifier activating enzyme 7
chr2_-_70663453 3.188 NM_172664
Tlk1
tousled-like kinase 1
chr13_-_54788995 3.181 Rnf44
ring finger protein 44
chr12_-_17006921 3.180 NM_001161111
NM_172574
Pqlc3

PQ loop repeat containing

chr16_+_23224955 3.176 St6gal1
beta galactoside alpha 2,6 sialyltransferase 1
chr15_-_102062309 3.171 Itgb7
integrin beta 7
chr16_+_23224804 3.160 NM_145933
St6gal1
beta galactoside alpha 2,6 sialyltransferase 1
chrX_+_70961935 3.111 NM_007435
Abcd1
ATP-binding cassette, sub-family D (ALD), member 1
chr7_-_134170532 3.110 Maz
MYC-associated zinc finger protein (purine-binding transcription factor)
chr9_+_47338449 3.100 Cadm1
cell adhesion molecule 1
chr15_-_78403110 3.074 NM_009008
Rac2
RAS-related C3 botulinum substrate 2
chr2_+_31325818 3.069 Ass1
argininosuccinate synthetase 1
chr17_+_79451501 3.053 Qpct
glutaminyl-peptide cyclotransferase (glutaminyl cyclase)
chr19_+_5637741 3.026 Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr17_+_34056367 3.024 NM_001025313
NM_009318
Tapbp

TAP binding protein

chr5_-_73259656 3.018 NM_001113460
NM_001113461
NM_001113464
Tec


tec protein tyrosine kinase


chr5_-_123582637 3.016 NM_175092
Rhof
ras homolog gene family, member f
chr14_+_51564224 3.016 Pnp
purine-nucleoside phosphorylase
chr15_+_81977633 2.981 NM_033218
Srebf2
sterol regulatory element binding factor 2
chr6_+_115311078 2.970 NM_001127330
Pparg
peroxisome proliferator activated receptor gamma
chr4_+_45197777 2.956 NM_001081172
Frmpd1
FERM and PDZ domain containing 1
chr2_+_31325763 2.952 NM_007494
Ass1
argininosuccinate synthetase 1
chr3_+_90417072 2.946 S100a6
S100 calcium binding protein A6 (calcyclin)
chr6_-_116411041 2.946 NM_009662
Alox5
arachidonate 5-lipoxygenase
chr13_+_52678541 2.939 Sykb
spleen tyrosine kinase
chr2_-_91035191 2.935 NM_013839
Nr1h3
nuclear receptor subfamily 1, group H, member 3
chr8_-_42459932 2.928 NM_019734
Asah1
N-acylsphingosine amidohydrolase 1
chr4_+_140258090 2.927 Rcc2
regulator of chromosome condensation 2
chr11_-_69734838 2.919 NM_001166589
NM_001166591
NM_181582
Eif5a


eukaryotic translation initiation factor 5A


chr3_+_90416815 2.885 NM_011313
S100a6
S100 calcium binding protein A6 (calcyclin)
chr11_+_115024626 2.882 NM_012030
Slc9a3r1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr13_-_74946095 2.880 Cast
calpastatin
chr14_+_51564176 2.859 Pnp
purine-nucleoside phosphorylase
chr14_-_121778143 2.854 Stk24
serine/threonine kinase 24 (STE20 homolog, yeast)
chr2_-_102741661 2.853 Cd44
CD44 antigen
chr8_-_26212588 2.851 Plekha2
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr17_+_31194623 2.838 NM_009593
Abcg1
ATP-binding cassette, sub-family G (WHITE), member 1
chr12_+_74685755 2.833 Prkch
protein kinase C, eta
chr18_-_60661144 2.816 2010002N04Rik
RIKEN cDNA 2010002N04 gene
chr2_-_174264400 2.816 NM_022325
Ctsz
cathepsin Z
chr6_+_115310883 2.813 Pparg
peroxisome proliferator activated receptor gamma
chr13_+_118009486 2.805 Emb
embigin
chr18_-_39650291 2.796 Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr18_-_42110847 2.785 NM_029942
Prelid2
PRELI domain containing 2
chr11_+_75465000 2.782 NM_008659
Myo1c
myosin IC
chr19_-_32462926 2.779 NM_144792
Sgms1
sphingomyelin synthase 1
chr1_-_52557130 2.776 NM_008667
Nab1
Ngfi-A binding protein 1
chr2_-_166539288 2.770 NM_177782
Prex1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr5_+_140981590 2.769 Chst12
carbohydrate sulfotransferase 12
chr7_+_129432810 2.765 Prkcb
protein kinase C, beta
chr7_+_57014881 2.754 NM_001146052
Htatip2
HIV-1 tat interactive protein 2, homolog (human)
chr9_-_45077167 2.750 NM_008348
Il10ra
interleukin 10 receptor, alpha
chr5_-_144288771 2.740 Rac1
RAS-related C3 botulinum substrate 1
chr15_-_73015345 2.740 NM_153178
Eif2c2
eukaryotic translation initiation factor 2C, 2
chr8_+_87396009 2.726 NM_001168246
NM_027954
NM_001168244
Syce2


synaptonemal complex central element protein 2


chr15_-_103085703 2.725 NM_008685
Nfe2
nuclear factor, erythroid derived 2
chr5_+_130417868 2.722 NM_001001327
NM_027121
Vkorc1l1

vitamin K epoxide reductase complex, subunit 1-like 1

chr19_+_5637712 2.722 Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr10_-_7675872 2.718 NM_138667
Tab2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr17_+_36005333 2.685 2310014H01Rik
RIKEN cDNA 2310014H01 gene
chr2_-_60800904 2.684 Rbms1
RNA binding motif, single stranded interacting protein 1
chr4_-_147525932 2.677 NM_001163704
NM_001163705
NM_015797
NM_001163706
NM_001163707
Fbxo6




F-box protein 6




chr14_+_79880952 2.676 NM_007920
Elf1
E74-like factor 1
chr8_+_74842931 2.659 NM_008452
Klf2
Kruppel-like factor 2 (lung)
chr10_-_20880559 2.628 NM_001198914
NM_010848
Myb

myeloblastosis oncogene

chr15_-_98593432 2.625 Arf3
ADP-ribosylation factor 3
chr2_+_167514489 2.623 Cebpb
CCAAT/enhancer binding protein (C/EBP), beta
chr2_-_90420626 2.620 NM_008982
Ptprj
protein tyrosine phosphatase, receptor type, J
chr7_-_87532756 2.613 NM_010194
Fes
feline sarcoma oncogene
chr15_+_79921725 2.612 NM_009303
NM_207708
Syngr1

synaptogyrin 1

chr19_+_29326204 2.612 NM_001048177
NM_008413
Jak2

Janus kinase 2

chr2_-_91035226 2.603 NM_001177730
Nr1h3
nuclear receptor subfamily 1, group H, member 3
chr11_+_62462155 2.591 NM_175002
Mmgt2
membrane magnesium transporter 2
chr2_-_102741483 2.586 Cd44
CD44 antigen
chr8_+_120022149 2.584 NM_172285
Plcg2
phospholipase C, gamma 2
chr7_-_3645124 2.575 NM_029934
Mboat7
membrane bound O-acyltransferase domain containing 7

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.37 4.58e-40 GO:0044237 cellular metabolic process
1.35 5.64e-38 GO:0044238 primary metabolic process
1.32 2.57e-37 GO:0008152 metabolic process
1.46 1.22e-32 GO:0019222 regulation of metabolic process
1.47 5.70e-30 GO:0031323 regulation of cellular metabolic process
1.39 4.07e-29 GO:0044260 cellular macromolecule metabolic process
1.47 5.42e-29 GO:0080090 regulation of primary metabolic process
1.36 7.05e-28 GO:0043170 macromolecule metabolic process
1.45 1.17e-25 GO:0060255 regulation of macromolecule metabolic process
1.48 6.20e-22 GO:0051171 regulation of nitrogen compound metabolic process
1.48 2.20e-21 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.14 1.09e-19 GO:0009987 cellular process
1.45 3.95e-19 GO:0048518 positive regulation of biological process
1.44 4.69e-19 GO:0016043 cellular component organization
1.46 5.73e-19 GO:0010468 regulation of gene expression
1.45 8.99e-19 GO:0031326 regulation of cellular biosynthetic process
1.42 1.31e-18 GO:0071840 cellular component organization or biogenesis
1.44 1.34e-18 GO:0009889 regulation of biosynthetic process
1.46 4.01e-18 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.60 5.23e-18 GO:0048583 regulation of response to stimulus
1.49 7.39e-18 GO:0044267 cellular protein metabolic process
1.45 1.54e-17 GO:0010556 regulation of macromolecule biosynthetic process
1.63 3.39e-17 GO:0006996 organelle organization
1.39 7.25e-17 GO:0044249 cellular biosynthetic process
1.35 8.90e-17 GO:0006807 nitrogen compound metabolic process
1.38 1.07e-16 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.38 2.84e-16 GO:0009058 biosynthetic process
1.56 5.07e-16 GO:0006464 protein modification process
1.35 5.66e-16 GO:0034641 cellular nitrogen compound metabolic process
1.45 6.04e-16 GO:0048519 negative regulation of biological process
1.45 6.21e-16 GO:0051252 regulation of RNA metabolic process
1.42 7.22e-16 GO:0019538 protein metabolic process
1.45 1.21e-15 GO:0006355 regulation of transcription, DNA-dependent
1.43 1.78e-15 GO:0048522 positive regulation of cellular process
1.36 7.27e-15 GO:0032502 developmental process
1.52 1.10e-14 GO:0043412 macromolecule modification
1.46 1.83e-14 GO:0048523 negative regulation of cellular process
1.56 3.40e-14 GO:0065009 regulation of molecular function
1.69 4.90e-14 GO:0006793 phosphorus metabolic process
1.35 4.99e-14 GO:0051179 localization
1.39 6.29e-14 GO:0048856 anatomical structure development
1.69 7.54e-14 GO:0006796 phosphate metabolic process
1.39 1.66e-13 GO:0051234 establishment of localization
1.37 1.33e-12 GO:0090304 nucleic acid metabolic process
1.38 1.53e-12 GO:0006810 transport
1.43 2.23e-12 GO:0071842 cellular component organization at cellular level
1.68 2.28e-12 GO:0002376 immune system process
1.41 3.06e-12 GO:0071841 cellular component organization or biogenesis at cellular level
1.39 5.73e-12 GO:0034645 cellular macromolecule biosynthetic process
1.59 5.83e-12 GO:0009966 regulation of signal transduction
1.62 1.13e-11 GO:0035556 intracellular signal transduction
1.34 1.49e-11 GO:0007275 multicellular organismal development
1.38 1.56e-11 GO:0048731 system development
1.38 2.57e-11 GO:0009059 macromolecule biosynthetic process
1.43 3.72e-11 GO:0030154 cell differentiation
1.45 7.24e-11 GO:0065008 regulation of biological quality
1.41 8.81e-11 GO:0048869 cellular developmental process
1.35 1.77e-10 GO:0010467 gene expression
1.55 3.11e-10 GO:0050790 regulation of catalytic activity
1.79 3.85e-10 GO:0002682 regulation of immune system process
1.44 3.87e-10 GO:0032774 RNA biosynthetic process
1.37 5.79e-10 GO:0016070 RNA metabolic process
1.49 6.54e-10 GO:0023051 regulation of signaling
1.43 7.99e-10 GO:0006351 transcription, DNA-dependent
1.15 8.84e-10 GO:0065007 biological regulation
1.41 4.97e-09 GO:0048513 organ development
1.88 5.35e-09 GO:0007010 cytoskeleton organization
1.63 5.59e-09 GO:0016310 phosphorylation
1.99 8.37e-09 GO:0002520 immune system development
2.10 1.13e-08 GO:0018193 peptidyl-amino acid modification
2.26 1.44e-08 GO:0030036 actin cytoskeleton organization
2.21 1.80e-08 GO:0030029 actin filament-based process
1.15 1.98e-08 GO:0050789 regulation of biological process
1.99 2.89e-08 GO:0048534 hemopoietic or lymphoid organ development
2.06 2.91e-08 GO:0030097 hemopoiesis
1.55 3.51e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.49 8.38e-08 GO:0033036 macromolecule localization
1.65 9.13e-08 GO:0006468 protein phosphorylation
1.56 1.16e-07 GO:0051173 positive regulation of nitrogen compound metabolic process
1.57 1.22e-07 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.46 1.42e-07 GO:0010604 positive regulation of macromolecule metabolic process
1.50 2.24e-07 GO:0009892 negative regulation of metabolic process
1.60 2.29e-07 GO:0048584 positive regulation of response to stimulus
1.58 2.76e-07 GO:0010628 positive regulation of gene expression
1.66 3.46e-07 GO:0012501 programmed cell death
1.95 4.32e-07 GO:0051098 regulation of binding
1.52 5.95e-07 GO:0032268 regulation of cellular protein metabolic process
1.49 5.97e-07 GO:0051246 regulation of protein metabolic process
1.14 7.74e-07 GO:0050794 regulation of cellular process
1.92 7.84e-07 GO:0032535 regulation of cellular component size
1.91 1.12e-06 GO:0035295 tube development
1.41 1.18e-06 GO:0009893 positive regulation of metabolic process
1.53 1.40e-06 GO:0010557 positive regulation of macromolecule biosynthetic process
1.57 1.52e-06 GO:0045595 regulation of cell differentiation
1.51 1.86e-06 GO:0031328 positive regulation of cellular biosynthetic process
1.83 1.98e-06 GO:0090066 regulation of anatomical structure size
2.40 2.02e-06 GO:0060541 respiratory system development
1.50 2.16e-06 GO:0009891 positive regulation of biosynthetic process
1.64 2.31e-06 GO:0006915 apoptosis
2.39 2.69e-06 GO:0002764 immune response-regulating signaling pathway
1.48 2.69e-06 GO:0010941 regulation of cell death
1.60 2.81e-06 GO:0008219 cell death
2.41 2.82e-06 GO:0002757 immune response-activating signal transduction
1.56 2.85e-06 GO:0051254 positive regulation of RNA metabolic process
1.48 2.93e-06 GO:0050793 regulation of developmental process
1.92 3.10e-06 GO:0001701 in utero embryonic development
2.47 3.14e-06 GO:0030323 respiratory tube development
1.80 3.28e-06 GO:0002684 positive regulation of immune system process
1.49 3.32e-06 GO:0010605 negative regulation of macromolecule metabolic process
1.48 3.38e-06 GO:0032879 regulation of localization
1.59 3.41e-06 GO:0016265 death
1.56 4.99e-06 GO:0045893 positive regulation of transcription, DNA-dependent
1.54 5.39e-06 GO:0007049 cell cycle
2.46 5.89e-06 GO:0030324 lung development
1.52 5.91e-06 GO:0051649 establishment of localization in cell
1.41 6.84e-06 GO:0031325 positive regulation of cellular metabolic process
1.72 7.66e-06 GO:0051726 regulation of cell cycle
1.85 8.53e-06 GO:0050776 regulation of immune response
1.58 9.11e-06 GO:0010629 negative regulation of gene expression
1.40 9.91e-06 GO:0009653 anatomical structure morphogenesis
1.48 1.09e-05 GO:0031324 negative regulation of cellular metabolic process
2.53 1.18e-05 GO:0030099 myeloid cell differentiation
1.98 1.71e-05 GO:0051056 regulation of small GTPase mediated signal transduction
1.61 1.91e-05 GO:0016192 vesicle-mediated transport
1.52 1.92e-05 GO:0009790 embryo development
1.58 2.61e-05 GO:0070887 cellular response to chemical stimulus
1.51 2.73e-05 GO:0051128 regulation of cellular component organization
2.17 3.24e-05 GO:0002253 activation of immune response
1.49 3.29e-05 GO:2000026 regulation of multicellular organismal development
1.33 3.36e-05 GO:0042221 response to chemical stimulus
1.58 3.81e-05 GO:0042325 regulation of phosphorylation
1.45 4.42e-05 GO:0043067 regulation of programmed cell death
1.44 5.06e-05 GO:0051641 cellular localization
1.51 5.09e-05 GO:0044093 positive regulation of molecular function
1.94 5.28e-05 GO:0050778 positive regulation of immune response
1.48 5.57e-05 GO:0022607 cellular component assembly
1.36 6.06e-05 GO:0051239 regulation of multicellular organismal process
1.45 7.36e-05 GO:0042981 regulation of apoptosis
1.63 7.61e-05 GO:0048646 anatomical structure formation involved in morphogenesis
1.39 8.64e-05 GO:0009056 catabolic process
1.80 8.84e-05 GO:0008283 cell proliferation
1.44 9.94e-05 GO:0008104 protein localization
1.63 1.13e-04 GO:0043009 chordate embryonic development
1.63 1.39e-04 GO:0009792 embryo development ending in birth or egg hatching
1.54 1.44e-04 GO:0019220 regulation of phosphate metabolic process
1.54 1.44e-04 GO:0051174 regulation of phosphorus metabolic process
1.58 1.47e-04 GO:0001932 regulation of protein phosphorylation
1.43 1.51e-04 GO:0044085 cellular component biogenesis
1.97 1.55e-04 GO:0046649 lymphocyte activation
1.56 1.88e-04 GO:0046907 intracellular transport
2.12 2.43e-04 GO:0002521 leukocyte differentiation
1.70 3.12e-04 GO:0000278 mitotic cell cycle
2.34 3.17e-04 GO:0006470 protein dephosphorylation
1.60 3.30e-04 GO:0010942 positive regulation of cell death
2.75 3.66e-04 GO:0008064 regulation of actin polymerization or depolymerization
1.76 4.00e-04 GO:0009894 regulation of catabolic process
1.48 4.20e-04 GO:0015031 protein transport
1.47 4.34e-04 GO:0045184 establishment of protein localization
3.22 4.53e-04 GO:0018108 peptidyl-tyrosine phosphorylation
3.22 4.53e-04 GO:0018212 peptidyl-tyrosine modification
1.38 4.56e-04 GO:0007399 nervous system development
2.05 4.56e-04 GO:0016311 dephosphorylation
2.71 5.26e-04 GO:0030832 regulation of actin filament length
1.31 5.57e-04 GO:0044281 small molecule metabolic process
1.67 5.71e-04 GO:0032583 regulation of gene-specific transcription
1.67 5.84e-04 GO:0043549 regulation of kinase activity
1.93 6.24e-04 GO:0046578 regulation of Ras protein signal transduction
1.87 6.43e-04 GO:0051101 regulation of DNA binding
1.47 7.06e-04 GO:0048699 generation of neurons
1.73 8.14e-04 GO:0051301 cell division
1.53 8.18e-04 GO:0051253 negative regulation of RNA metabolic process
1.39 8.46e-04 GO:0010033 response to organic substance
1.47 9.00e-04 GO:0031399 regulation of protein modification process
3.04 9.03e-04 GO:0030218 erythrocyte differentiation
1.73 9.56e-04 GO:0016568 chromatin modification
1.68 9.59e-04 GO:0045859 regulation of protein kinase activity
1.59 1.07e-03 GO:0043068 positive regulation of programmed cell death
2.03 1.08e-03 GO:0051493 regulation of cytoskeleton organization
2.85 1.20e-03 GO:0034101 erythrocyte homeostasis
1.63 1.34e-03 GO:0051338 regulation of transferase activity
1.39 1.35e-03 GO:0044248 cellular catabolic process
2.71 1.39e-03 GO:0051494 negative regulation of cytoskeleton organization
1.46 1.57e-03 GO:0031327 negative regulation of cellular biosynthetic process
2.09 1.60e-03 GO:0051099 positive regulation of binding
1.57 1.67e-03 GO:0051276 chromosome organization
1.51 1.71e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.49 1.73e-03 GO:0033554 cellular response to stress
2.74 1.90e-03 GO:0002756 MyD88-independent toll-like receptor signaling pathway
1.64 1.92e-03 GO:0045597 positive regulation of cell differentiation
1.53 2.13e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.38 2.16e-03 GO:0010646 regulation of cell communication
1.57 2.25e-03 GO:0043065 positive regulation of apoptosis
1.77 2.41e-03 GO:0007264 small GTPase mediated signal transduction
1.69 2.47e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.47 2.60e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.45 2.62e-03 GO:0009890 negative regulation of biosynthetic process
1.61 2.67e-03 GO:0022403 cell cycle phase
1.72 2.70e-03 GO:0001775 cell activation
1.57 2.72e-03 GO:0006753 nucleoside phosphate metabolic process
1.57 2.72e-03 GO:0009117 nucleotide metabolic process
2.16 2.77e-03 GO:0048872 homeostasis of number of cells
1.47 3.12e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.77 3.25e-03 GO:0045321 leukocyte activation
1.77 3.25e-03 GO:0031329 regulation of cellular catabolic process
1.41 3.29e-03 GO:0042592 homeostatic process
2.46 3.78e-03 GO:0002224 toll-like receptor signaling pathway
2.16 3.88e-03 GO:0030098 lymphocyte differentiation
2.31 4.06e-03 GO:0046777 protein autophosphorylation
2.23 4.10e-03 GO:0032970 regulation of actin filament-based process
1.67 4.18e-03 GO:0007243 intracellular protein kinase cascade
1.67 4.18e-03 GO:0023014 signal transduction via phosphorylation event
1.42 4.33e-03 GO:0022008 neurogenesis
2.25 4.48e-03 GO:0032956 regulation of actin cytoskeleton organization
1.57 4.59e-03 GO:0071822 protein complex subunit organization
1.57 5.32e-03 GO:0080134 regulation of response to stress
1.42 6.67e-03 GO:0006629 lipid metabolic process
1.73 6.73e-03 GO:0009144 purine nucleoside triphosphate metabolic process
1.82 7.68e-03 GO:0048732 gland development
1.81 7.78e-03 GO:0051129 negative regulation of cellular component organization
1.50 8.01e-03 GO:0071844 cellular component assembly at cellular level
1.70 8.58e-03 GO:0009150 purine ribonucleotide metabolic process
1.45 9.29e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.58 9.32e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.52 9.55e-03 GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
1.71 1.01e-02 GO:0009141 nucleoside triphosphate metabolic process
1.67 1.04e-02 GO:0051270 regulation of cellular component movement
1.43 1.04e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.47 1.04e-02 GO:0046483 heterocycle metabolic process
2.38 1.26e-02 GO:0032271 regulation of protein polymerization
1.87 1.29e-02 GO:0016570 histone modification
2.42 1.33e-02 GO:0007015 actin filament organization
2.50 1.42e-02 GO:0002755 MyD88-dependent toll-like receptor signaling pathway
1.67 1.43e-02 GO:0009259 ribonucleotide metabolic process
1.60 1.44e-02 GO:0006066 alcohol metabolic process
1.60 1.44e-02 GO:0006325 chromatin organization
1.69 1.52e-02 GO:0030334 regulation of cell migration
3.63 1.57e-02 GO:0030834 regulation of actin filament depolymerization
1.55 1.66e-02 GO:0070271 protein complex biogenesis
1.52 1.67e-02 GO:0051336 regulation of hydrolase activity
2.27 1.88e-02 GO:0045637 regulation of myeloid cell differentiation
2.30 2.03e-02 GO:0002221 pattern recognition receptor signaling pathway
1.84 2.14e-02 GO:0016569 covalent chromatin modification
1.77 2.27e-02 GO:0043193 positive regulation of gene-specific transcription
1.54 2.37e-02 GO:0006461 protein complex assembly
1.70 2.44e-02 GO:0009205 purine ribonucleoside triphosphate metabolic process
2.81 2.47e-02 GO:0031333 negative regulation of protein complex assembly
3.10 2.48e-02 GO:0032272 negative regulation of protein polymerization
1.67 2.57e-02 GO:2000145 regulation of cell motility
1.49 2.64e-02 GO:0051094 positive regulation of developmental process
1.37 2.69e-02 GO:0009888 tissue development
1.58 2.85e-02 GO:0010627 regulation of intracellular protein kinase cascade
1.52 2.86e-02 GO:0071310 cellular response to organic substance
1.56 3.16e-02 GO:0060284 regulation of cell development
1.68 3.19e-02 GO:0009199 ribonucleoside triphosphate metabolic process
1.54 3.31e-02 GO:0061024 membrane organization
1.66 3.33e-02 GO:0033043 regulation of organelle organization
2.25 3.40e-02 GO:0002758 innate immune response-activating signal transduction
1.36 3.55e-02 GO:0042127 regulation of cell proliferation
2.07 3.59e-02 GO:0043388 positive regulation of DNA binding
1.95 3.68e-02 GO:0030811 regulation of nucleotide catabolic process
1.95 3.68e-02 GO:0033121 regulation of purine nucleotide catabolic process
1.74 4.11e-02 GO:0000087 M phase of mitotic cell cycle
1.57 4.13e-02 GO:0009968 negative regulation of signal transduction
1.75 4.13e-02 GO:0000280 nuclear division
1.75 4.13e-02 GO:0007067 mitosis
1.53 4.14e-02 GO:0006928 cellular component movement
1.61 4.56e-02 GO:0050767 regulation of neurogenesis
1.53 4.72e-02 GO:0016044 cellular membrane organization
1.58 4.81e-02 GO:0006163 purine nucleotide metabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.33 7.80e-86 GO:0044424 intracellular part
1.32 1.10e-85 GO:0005622 intracellular
1.34 1.81e-67 GO:0043229 intracellular organelle
1.34 3.12e-67 GO:0043226 organelle
1.38 3.51e-65 GO:0005737 cytoplasm
1.37 5.79e-65 GO:0043227 membrane-bounded organelle
1.37 3.28e-64 GO:0043231 intracellular membrane-bounded organelle
1.45 5.50e-44 GO:0005634 nucleus
1.40 2.81e-40 GO:0044444 cytoplasmic part
1.13 5.24e-37 GO:0005623 cell
1.13 5.24e-37 GO:0044464 cell part
1.42 5.79e-30 GO:0044422 organelle part
1.42 1.06e-29 GO:0044446 intracellular organelle part
1.68 1.81e-22 GO:0005829 cytosol
1.58 4.16e-20 GO:0044428 nuclear part
1.54 9.53e-17 GO:0031974 membrane-enclosed lumen
1.59 1.17e-16 GO:0031981 nuclear lumen
1.54 2.23e-16 GO:0070013 intracellular organelle lumen
1.54 3.08e-16 GO:0043233 organelle lumen
1.35 3.26e-15 GO:0032991 macromolecular complex
1.42 6.42e-15 GO:0043228 non-membrane-bounded organelle
1.42 6.42e-15 GO:0043232 intracellular non-membrane-bounded organelle
1.38 8.40e-15 GO:0043234 protein complex
1.57 4.01e-10 GO:0005654 nucleoplasm
1.48 1.58e-08 GO:0000267 cell fraction
1.39 4.31e-07 GO:0005856 cytoskeleton
1.43 5.03e-07 GO:0031090 organelle membrane
1.48 1.57e-06 GO:0005794 Golgi apparatus
1.53 1.93e-06 GO:0012505 endomembrane system
1.56 3.68e-06 GO:0044451 nucleoplasm part
1.47 6.19e-06 GO:0005626 insoluble fraction
1.75 9.45e-06 GO:0005730 nucleolus
1.41 2.93e-05 GO:0005783 endoplasmic reticulum
1.44 6.75e-05 GO:0005624 membrane fraction
1.76 1.21e-04 GO:0048471 perinuclear region of cytoplasm
1.69 1.66e-04 GO:0005625 soluble fraction
2.01 1.67e-04 GO:0031252 cell leading edge
1.85 2.03e-04 GO:0000323 lytic vacuole
1.85 2.03e-04 GO:0005764 lysosome
1.60 3.08e-04 GO:0005768 endosome
1.75 3.99e-04 GO:0005773 vacuole
1.40 4.04e-04 GO:0044430 cytoskeletal part
1.17 1.32e-03 GO:0071944 cell periphery
1.58 1.34e-03 GO:0044427 chromosomal part
1.34 1.34e-03 GO:0042995 cell projection
1.53 2.86e-03 GO:0005694 chromosome
2.30 4.10e-03 GO:0030027 lamellipodium
1.24 5.48e-03 GO:0044459 plasma membrane part
1.45 7.25e-03 GO:0015630 microtubule cytoskeleton
2.69 7.39e-03 GO:0030496 midbody
1.26 8.79e-03 GO:0005739 mitochondrion
1.91 9.15e-03 GO:0005938 cell cortex
1.16 9.69e-03 GO:0005886 plasma membrane
1.42 1.08e-02 GO:0031975 envelope
1.64 1.13e-02 GO:0042175 nuclear membrane-endoplasmic reticulum network
1.41 1.30e-02 GO:0031967 organelle envelope
1.59 3.18e-02 GO:0044431 Golgi apparatus part
1.61 3.36e-02 GO:0005789 endoplasmic reticulum membrane
1.74 3.57e-02 GO:0005635 nuclear envelope
2.40 3.58e-02 GO:0034708 methyltransferase complex
2.40 3.58e-02 GO:0035097 histone methyltransferase complex
1.58 4.29e-02 GO:0015629 actin cytoskeleton

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.23 3.85e-43 GO:0005488 binding
1.40 1.87e-40 GO:0005515 protein binding
1.26 1.92e-15 GO:0003824 catalytic activity
1.40 1.27e-11 GO:0000166 nucleotide binding
1.28 1.53e-09 GO:0043167 ion binding
1.27 2.22e-09 GO:0043169 cation binding
1.61 2.84e-09 GO:0030234 enzyme regulator activity
1.27 5.99e-09 GO:0046872 metal ion binding
1.58 1.12e-07 GO:0042802 identical protein binding
1.37 2.12e-07 GO:0016740 transferase activity
1.53 6.12e-07 GO:0019899 enzyme binding
1.60 6.68e-07 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.90 6.73e-07 GO:0042578 phosphoric ester hydrolase activity
1.69 8.27e-07 GO:0008092 cytoskeletal protein binding
1.37 9.48e-07 GO:0046914 transition metal ion binding
1.68 1.05e-06 GO:0019904 protein domain specific binding
1.35 1.10e-06 GO:0017076 purine nucleotide binding
1.34 2.28e-06 GO:0032555 purine ribonucleotide binding
1.34 2.44e-06 GO:0032553 ribonucleotide binding
1.34 2.48e-06 GO:0035639 purine ribonucleoside triphosphate binding
1.48 2.69e-06 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.27 3.25e-06 GO:0003676 nucleic acid binding
1.52 3.62e-06 GO:0016301 kinase activity
1.74 5.22e-06 GO:0004674 protein serine/threonine kinase activity
1.73 1.27e-05 GO:0030695 GTPase regulator activity
1.71 1.64e-05 GO:0060589 nucleoside-triphosphatase regulator activity
1.81 2.71e-05 GO:0008134 transcription factor binding
1.52 2.92e-05 GO:0046983 protein dimerization activity
1.82 3.10e-05 GO:0003779 actin binding
1.82 3.10e-05 GO:0019900 kinase binding
2.17 3.64e-05 GO:0004721 phosphoprotein phosphatase activity
1.31 4.03e-05 GO:0003677 DNA binding
1.27 9.10e-05 GO:0016787 hydrolase activity
1.89 1.03e-04 GO:0016791 phosphatase activity
1.56 1.28e-04 GO:0004672 protein kinase activity
1.33 1.58e-04 GO:0030554 adenyl nucleotide binding
1.50 1.61e-04 GO:0016788 hydrolase activity, acting on ester bonds
1.47 1.63e-04 GO:0001071 nucleic acid binding transcription factor activity
1.47 1.63e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.34 1.65e-04 GO:0008270 zinc ion binding
1.32 3.15e-04 GO:0032559 adenyl ribonucleotide binding
1.83 3.38e-04 GO:0019901 protein kinase binding
1.92 3.62e-04 GO:0003682 chromatin binding
1.82 3.97e-04 GO:0005083 small GTPase regulator activity
3.21 4.96e-04 GO:0004722 protein serine/threonine phosphatase activity
1.32 6.10e-04 GO:0005524 ATP binding
1.66 8.94e-04 GO:0032403 protein complex binding
1.70 9.22e-04 GO:0016564 transcription repressor activity
1.40 1.03e-03 GO:0030528 transcription regulator activity
1.52 4.46e-03 GO:0042803 protein homodimerization activity
1.80 6.97e-03 GO:0005096 GTPase activator activity
1.64 7.98e-03 GO:0008047 enzyme activator activity
1.43 9.39e-03 GO:0043565 sequence-specific DNA binding
2.20 1.06e-02 GO:0051427 hormone receptor binding
1.92 1.23e-02 GO:0000287 magnesium ion binding
1.73 2.67e-02 GO:0000975 regulatory region DNA binding
1.73 2.67e-02 GO:0001067 regulatory region nucleic acid binding
1.73 2.67e-02 GO:0044212 transcription regulatory region DNA binding
2.22 3.21e-02 GO:0035257 nuclear hormone receptor binding
1.74 3.64e-02 GO:0010843 promoter binding