Motif ID: ZNF238.p2

Z-value: 2.058


Transcription factors associated with ZNF238.p2:

Gene SymbolEntrez IDGene Name
Zfp238 30928 zinc finger protein 238

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp238chr1_+_179375951,
chr1_+_179372452,
chr1_+_179374783
-0.423.0e-09Click!


Activity profile for motif ZNF238.p2.

activity profile for motif ZNF238.p2


Sorted Z-values histogram for motif ZNF238.p2

Sorted Z-values for motif ZNF238.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF238.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_45368443 47.415 Col3a1
collagen, type III, alpha 1
chr3_+_90407688 39.770 NM_011311
S100a4
S100 calcium binding protein A4
chr1_+_45368382 35.763 NM_009930
Col3a1
collagen, type III, alpha 1
chr6_+_4471231 33.027 Col1a2
collagen, type I, alpha 2
chr19_+_34365165 32.455 Fas
Fas (TNF receptor superfamily member 6)
chr19_+_34365146 31.959 NM_001146708
NM_007987
Fas

Fas (TNF receptor superfamily member 6)

chr9_+_40494076 30.534 9030425E11Rik
RIKEN cDNA 9030425E11 gene
chr18_+_9707674 29.541 Colec12
collectin sub-family member 12
chr18_+_9707574 28.705 NM_130449
Colec12
collectin sub-family member 12
chr2_+_125860377 28.210 NM_008008
Fgf7
fibroblast growth factor 7
chr9_-_116084154 27.192 Tgfbr2
transforming growth factor, beta receptor II
chr2_+_125860507 27.141 Fgf7
fibroblast growth factor 7
chr9_-_20781133 26.640 S1pr2
sphingosine-1-phosphate receptor 2
chr9_-_20781206 26.166 NM_010333
S1pr2
sphingosine-1-phosphate receptor 2
chr11_+_50415579 26.071 NM_175643
Adamts2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
chr9_-_116084547 25.794 Tgfbr2
transforming growth factor, beta receptor II
chr7_+_3290587 25.716 Myadm
myeloid-associated differentiation marker
chr14_+_63756868 25.586 Ctsb
cathepsin B
chr7_-_86993011 24.881 Anpep
alanyl (membrane) aminopeptidase
chrX_+_156278399 24.530 NM_001135728
Sh3kbp1
SH3-domain kinase binding protein 1
chr17_-_71196116 24.058 NM_001164077
Tgif1
TGFB-induced factor homeobox 1
chr17_-_45729199 23.918 NM_022880
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr7_+_3290516 23.153 NM_016969
NM_001093765
Myadm

myeloid-associated differentiation marker

chr16_-_56886260 22.779 NM_019631
Tmem45a
transmembrane protein 45a
chr1_-_193007202 22.536 NM_007498
Atf3
activating transcription factor 3
chr7_+_3290622 22.479 Myadm
myeloid-associated differentiation marker
chr19_+_34365195 22.119 Fas
Fas (TNF receptor superfamily member 6)
chrX_+_130385546 21.859 NM_022322
Tnmd
tenomodulin
chr4_-_141154138 21.476 Fblim1
filamin binding LIM protein 1
chr2_+_145685882 21.440 Rin2
Ras and Rab interactor 2
chr9_+_40494347 21.399 9030425E11Rik
RIKEN cDNA 9030425E11 gene
chr9_-_116084395 20.808 NM_009371
NM_029575
Tgfbr2

transforming growth factor, beta receptor II

chr1_-_193006986 20.337 Atf3
activating transcription factor 3
chr7_-_106501642 20.334 NM_001111043
NM_001111044
NM_009825
Serpinh1


serine (or cysteine) peptidase inhibitor, clade H, member 1


chrX_+_130385690 20.006 Tnmd
tenomodulin
chrX_-_163023624 19.709 NM_019397
Egfl6
EGF-like-domain, multiple 6
chr11_+_105153956 19.634 NM_008626
Mrc2
mannose receptor, C type 2
chr7_-_106501584 19.340 Serpinh1
serine (or cysteine) peptidase inhibitor, clade H, member 1
chr7_-_106501620 19.253 Serpinh1
serine (or cysteine) peptidase inhibitor, clade H, member 1
chr1_+_166726827 19.151 NM_019759
Dpt
dermatopontin
chr2_+_145686480 18.421 Rin2
Ras and Rab interactor 2
chr13_+_33119282 18.309 NM_011452
Serpinb9b
serine (or cysteine) peptidase inhibitor, clade B, member 9b
chr9_+_108959702 18.174 Shisa5
shisa homolog 5 (Xenopus laevis)
chr11_-_99527240 18.040 NM_026834
Krtap4-6
keratin associated protein 4-6
chr2_+_158157639 17.814 Lbp
lipopolysaccharide binding protein
chr15_-_99200748 17.630 Fmnl3
formin-like 3
chrX_+_130442964 17.358 NM_001083895
NM_026838
Srpx2

sushi-repeat-containing protein, X-linked 2

chr15_+_78757171 17.249 Lgals1
lectin, galactose binding, soluble 1
chr14_+_51716032 17.149 Ang
Rnase4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family 4
chr5_-_4758060 17.149 NM_021457
Fzd1
frizzled homolog 1 (Drosophila)
chr2_+_145686377 16.504 Rin2
Ras and Rab interactor 2
chr7_+_152486800 16.269 NM_145379
Mrgprf
MAS-related GPR, member F
chr3_-_27316628 15.182 Fndc3b
fibronectin type III domain containing 3B
chr2_-_60800904 15.064 Rbms1
RNA binding motif, single stranded interacting protein 1
chr11_-_99520272 14.718 NM_001126320
Gm11563
predicted gene 11563
chr9_+_108953672 14.513 Shisa5
shisa homolog 5 (Xenopus laevis)
chr11_+_101192080 14.267 Aoc3
amine oxidase, copper containing 3
chr5_-_145891052 14.161 Pdap1
PDGFA associated protein 1
chr8_+_90812964 14.145 NM_001037723
Adcy7
adenylate cyclase 7
chr6_-_122799694 14.106 C3ar1
complement component 3a receptor 1
chr11_-_99665759 14.002 NM_001099312
NM_001099313
NM_027087
Gm11569
Gm11554
Krtap4-13
predicted gene 11569
predicted gene 11554
keratin associated protein 4-13
chr3_+_79690082 13.950 Fam198b
family with sequence similarity 198, member B
chr14_+_51715674 13.806 NM_007447
NM_201239
Ang
Rnase4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family 4
chr9_+_108953692 13.711 Shisa5
shisa homolog 5 (Xenopus laevis)
chr9_-_71959599 13.510 NM_011544
Tcf12
transcription factor 12
chr11_-_99489523 13.508 NM_001048196
Krtap4-1
keratin associated protein 4-1
chr11_+_101191918 13.249 NM_009675
Aoc3
amine oxidase, copper containing 3
chr16_+_62854129 13.019 NM_011173
Pros1
protein S (alpha)
chr15_+_78757148 12.604 NM_008495
Lgals1
lectin, galactose binding, soluble 1
chr8_-_107779002 12.467 B3gnt9-ps
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9, pseudogene
chr13_+_94827750 12.197 NM_172589
Lhfpl2
lipoma HMGIC fusion partner-like 2
chr3_-_83645593 12.046 Tlr2
toll-like receptor 2
chr7_-_52317021 11.918 NM_022999
Prrg2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr4_+_139131050 11.778 NM_183148
Iffo2
intermediate filament family orphan 2
chr8_-_107779027 11.477 NM_178879
B3gnt9-ps
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9, pseudogene
chr8_+_42011568 11.437 NM_026840
Pdgfrl
platelet-derived growth factor receptor-like
chr3_-_83645460 11.282 Tlr2
toll-like receptor 2
chr12_+_75028976 11.086 Hif1a
hypoxia inducible factor 1, alpha subunit
chr6_+_72306146 11.074 Tmem150a
transmembrane protein 150A
chr11_+_117127762 10.805 Sept9
septin 9
chr8_-_122071463 10.780 Mbtps1
membrane-bound transcription factor peptidase, site 1
chrX_-_34404128 10.761 NM_029951
C330007P06Rik
RIKEN cDNA C330007P06 gene
chr10_+_79457716 10.760 Cnn2
calponin 2
chr3_+_79689897 10.749 Fam198b
family with sequence similarity 198, member B
chr11_-_7113899 10.631 NM_008343
Igfbp3
insulin-like growth factor binding protein 3
chr4_-_107704544 10.563 NM_172874
Podn
podocan
chr5_-_5380077 10.553 NM_011074
Cdk14
cyclin-dependent kinase 14
chr7_-_29157512 10.452 NM_001083912
NM_138752
Plekhg2

pleckstrin homology domain containing, family G (with RhoGef domain) member 2

chr1_-_192802869 10.393 NM_144879
Vash2
vasohibin 2
chrX_-_140261831 10.325 Capn6
calpain 6
chr3_-_108525202 9.944 NM_029522
Gpsm2
G-protein signalling modulator 2 (AGS3-like, C. elegans)
chr14_+_120674921 9.848 Mbnl2
muscleblind-like 2
chr14_+_120674933 9.844 Mbnl2
muscleblind-like 2
chr10_+_76729969 9.832 Pofut2
protein O-fucosyltransferase 2
chr6_+_72305440 9.640 NM_144916
Tmem150a
transmembrane protein 150A
chr1_-_175842977 9.616 NM_001033450
Ifi204
Mnda
interferon activated gene 204
myeloid cell nuclear differentiation antigen
chr14_+_32454236 9.539 NM_025295
Btd
biotinidase
chr7_-_91300359 9.532 NM_133722
Fam108c
family with sequence similarity 108, member C
chr17_-_34999458 9.464 NM_001142706
NM_008198
Cfb

complement factor B

chr2_-_60590923 9.446 Rbms1
RNA binding motif, single stranded interacting protein 1
chr3_-_83645515 9.355 NM_011905
Tlr2
toll-like receptor 2
chrX_-_140261954 9.254 NM_007603
Capn6
calpain 6
chr18_-_60783946 9.166 NM_177340
Synpo
synaptopodin
chr3_+_127494295 9.165 Tifa
TRAF-interacting protein with forkhead-associated domain
chr1_-_152313294 9.116 NM_001110146
NM_021400
Prg4

proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)

chr1_-_175671849 9.003 AI607873
expressed sequence AI607873
chr2_-_91864276 8.925 NM_011957
Creb3l1
cAMP responsive element binding protein 3-like 1
chr11_-_70465629 8.918 Pfn1
profilin 1
chr15_-_103196944 8.750 Itga5
integrin alpha 5 (fibronectin receptor alpha)
chr2_+_139503913 8.726 NM_001126490
Ism1
isthmin 1 homolog (zebrafish)
chr14_+_120674886 8.640 NM_175341
NM_207515
Mbnl2

muscleblind-like 2

chr1_-_192803077 8.604 Vash2
vasohibin 2
chr11_+_117127516 8.540 NM_001113487
Sept9
septin 9
chr7_+_25378887 8.526 Ethe1
ethylmalonic encephalopathy 1
chr11_+_120358702 8.414


chr7_+_148748102 8.412 Ap2a2
adaptor protein complex AP-2, alpha 2 subunit
chr10_+_76993060 8.349 NM_008404
Itgb2
integrin beta 2
chr17_-_14831233 8.341 Thbs2
thrombospondin 2
chr10_+_77060408 8.228 Pttg1ip
pituitary tumor-transforming 1 interacting protein
chr6_+_117118552 8.193 NM_001012477
NM_013655
NM_021704
Cxcl12


chemokine (C-X-C motif) ligand 12


chr7_-_149482973 8.080 NM_015808
Krtap5-1
keratin associated protein 5-1
chr8_-_118230771 8.052 NM_001025577
Maf
avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog
chr2_-_62411970 8.022 NM_007986
Fap
fibroblast activation protein
chr15_-_77599271 7.796 Myh9
myosin, heavy polypeptide 9, non-muscle
chr19_-_5663619 7.730 NM_001164480
NM_001164481
NM_001164482
NM_001164568
NM_011379
Sipa1




signal-induced proliferation associated gene 1




chrX_+_20451640 7.725 Timp1
tissue inhibitor of metalloproteinase 1
chr2_+_174170886 7.655 Gnas
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr10_+_76727739 7.631 Pofut2
protein O-fucosyltransferase 2
chr3_-_83645498 7.591 Tlr2
toll-like receptor 2
chr19_+_42221868 7.509 NM_183195
Marveld1
MARVEL (membrane-associating) domain containing 1
chr2_-_60591836 7.481 Rbms1
RNA binding motif, single stranded interacting protein 1
chr5_-_114250360 7.449 NM_146162
Tmem119
transmembrane protein 119
chr15_-_103197178 7.285 NM_010577
Itga5
integrin alpha 5 (fibronectin receptor alpha)
chr2_-_32136262 7.018


chr17_-_14831262 6.822 NM_011581
Thbs2
thrombospondin 2
chr9_-_48288689 6.776 Rexo2
REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chr19_+_47253626 6.715 Neurl1a
neuralized homolog 1A (Drosophila)
chr17_-_34134101 6.659 H2-K1
histocompatibility 2, K1, K region
chr14_+_120674913 6.582 Mbnl2
muscleblind-like 2
chr17_-_14831058 6.570 Thbs2
thrombospondin 2
chr11_-_114795651 6.475 NM_199221
Cd300lb
CD300 antigen like family member B
chr12_+_114252715 6.401 NM_001081170
Pacs2
phosphofurin acidic cluster sorting protein 2
chr17_-_34134309 6.364 H2-K1
histocompatibility 2, K1, K region
chr11_-_55421246 6.221 NM_020492
Glra1
glycine receptor, alpha 1 subunit
chr10_-_116719364 6.172 Lyz2
lysozyme 2
chr9_-_48288692 6.135 NM_024233
Rexo2
REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chr19_+_47253657 6.131 Neurl1a
neuralized homolog 1A (Drosophila)
chr4_+_140566338 6.129 NM_001161799
Mfap2
microfibrillar-associated protein 2
chr17_+_75578120 6.077 NM_206958
Ltbp1
latent transforming growth factor beta binding protein 1
chr10_+_87323855 6.010 NM_001111274
NM_001111276
NM_184052
Igf1


insulin-like growth factor 1


chr2_+_143741243 5.997 Dstn
destrin
chr8_+_82235708 5.968 NM_026904
Anapc10
anaphase promoting complex subunit 10
chr11_-_99671205 5.947 NM_001099313
NM_027087
Gm11554
Krtap4-13
predicted gene 11554
keratin associated protein 4-13
chr19_+_5492584 5.947


chr11_-_5737970 5.924 NM_017401
Polm
polymerase (DNA directed), mu
chr17_-_14831095 5.906 Thbs2
thrombospondin 2
chr6_+_17413930 5.891 NM_008591
Met
met proto-oncogene
chr10_-_83903215 5.871 NM_001004363
Nuak1
NUAK family, SNF1-like kinase, 1
chr10_-_86164623 5.804 Hsp90b1
heat shock protein 90, beta (Grp94), member 1
chr12_-_59370171 5.789 NM_025809
Clec14a
C-type lectin domain family 14, member a
chr17_+_75784448 5.765 Ltbp1
latent transforming growth factor beta binding protein 1
chr9_-_110959702 5.728 NM_017466
Ccrl2
chemokine (C-C motif) receptor-like 2
chr8_-_66684789 5.678 NM_009390
Tll1
tolloid-like
chrX_+_16196823 5.584 NM_173740
Maoa
monoamine oxidase A
chr13_-_64468380 5.555 Ctsl
cathepsin L
chr4_-_141161882 5.552 NM_133754
Fblim1
filamin binding LIM protein 1
chr1_-_122167658 5.522 NM_001085409
Steap3
STEAP family member 3
chr9_-_110959315 5.446 Ccrl2
chemokine (C-C motif) receptor-like 2
chr7_-_87080143 5.358 NM_027420
2610034B18Rik
RIKEN cDNA 2610034B18 gene
chr3_+_145587194 5.310 NM_009740
Bcl10
B-cell leukemia/lymphoma 10
chr7_-_15208414 5.310 NM_001039146
Vmn1r90
vomeronasal 1 receptor 90
chr8_-_109927080 5.298 NM_008706
Nqo1
NAD(P)H dehydrogenase, quinone 1
chr5_+_23907911 5.271 Abcb8
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr2_+_174171525 5.235 Gnas
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr2_+_91050920 5.220 Acp2
acid phosphatase 2, lysosomal
chr15_-_97738692 5.149 NM_009504
Vdr
vitamin D receptor
chr10_-_82153323 5.149 NM_029102
Glt8d2
glycosyltransferase 8 domain containing 2
chr2_+_143741050 5.129 NM_019771
Dstn
destrin
chr5_+_145888588 5.074 Arpc1b
actin related protein 2/3 complex, subunit 1B
chr2_+_173936677 5.043 Npepl1
aminopeptidase-like 1
chr17_-_27165478 4.999 NM_007523
Bak1
BCL2-antagonist/killer 1
chr9_-_110524649 4.927 Nradd
neurotrophin receptor associated death domain
chr3_-_68848588 4.922 Trim59
tripartite motif-containing 59
chrX_+_106290703 4.884 NM_019989
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chr7_-_133929984 4.854 Ppp4c
protein phosphatase 4, catalytic subunit
chr3_-_68848657 4.851 NM_025863
Trim59
tripartite motif-containing 59
chr8_-_82235601 4.828 NM_015751
Abce1
ATP-binding cassette, sub-family E (OABP), member 1
chr5_+_65221116 4.795 Klf3
Kruppel-like factor 3 (basic)
chr4_+_140566594 4.773 Mfap2
microfibrillar-associated protein 2
chr4_-_135577545 4.762 NM_013736
Tceb3
transcription elongation factor B (SIII), polypeptide 3
chr8_-_105308910 4.698 NM_009866
Cdh11
cadherin 11
chr16_+_17452048 4.694 NM_007764
Crkl
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr14_+_103446209 4.685 NM_008392
Irg1
immunoresponsive gene 1
chr8_-_129117310 4.620 NM_001164598
Irf2bp2
interferon regulatory factor 2 binding protein 2
chr19_-_41459518 4.595 NM_031376
Pik3ap1
phosphoinositide-3-kinase adaptor protein 1
chr14_+_103446193 4.576 Irg1
immunoresponsive gene 1
chr3_+_79689851 4.569 NM_133187
Fam198b
family with sequence similarity 198, member B
chr1_+_133534852 4.534 NM_007799
Ctse
cathepsin E
chr4_+_6292817 4.529 NM_001098227
NM_016807
Sdcbp

syndecan binding protein

chr17_+_35403130 4.482 H2-D1
histocompatibility 2, D region locus 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.75 1.87e-06 GO:0048518 positive regulation of biological process
2.41 7.57e-06 GO:0002376 immune system process
1.72 5.11e-05 GO:0048522 positive regulation of cellular process
3.00 4.33e-04 GO:0009611 response to wounding
2.90 8.84e-03 GO:0035295 tube development
3.44 9.33e-03 GO:0006954 inflammatory response
3.34 1.37e-02 GO:0030036 actin cytoskeleton organization
1.71 2.79e-02 GO:0006950 response to stress
1.75 2.86e-02 GO:0051239 regulation of multicellular organismal process
1.67 3.03e-02 GO:0042221 response to chemical stimulus
3.14 3.21e-02 GO:0030029 actin filament-based process
2.32 4.36e-02 GO:0051094 positive regulation of developmental process
2.86 4.38e-02 GO:0030334 regulation of cell migration

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.63 1.83e-09 GO:0044421 extracellular region part
2.03 3.88e-08 GO:0005576 extracellular region
1.26 4.75e-07 GO:0044424 intracellular part
1.25 5.07e-07 GO:0005622 intracellular
2.61 1.10e-06 GO:0005615 extracellular space
1.29 8.38e-05 GO:0005737 cytoplasm
3.14 1.24e-04 GO:0031012 extracellular matrix
1.25 1.52e-04 GO:0043226 organelle
4.17 1.76e-04 GO:0045111 intermediate filament cytoskeleton
1.25 1.80e-04 GO:0043229 intracellular organelle
4.50 3.03e-04 GO:0005882 intermediate filament
3.14 5.91e-04 GO:0005578 proteinaceous extracellular matrix
1.12 6.00e-04 GO:0005623 cell
1.12 6.00e-04 GO:0044464 cell part
3.22 5.90e-03 GO:0009897 external side of plasma membrane
1.69 1.52e-02 GO:0005856 cytoskeleton
1.29 2.14e-02 GO:0044444 cytoplasmic part
2.28 2.17e-02 GO:0009986 cell surface
1.34 3.41e-02 GO:0044422 organelle part

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.42 7.45e-06 GO:0005515 protein binding
1.22 7.96e-05 GO:0005488 binding