ISMARA results: GCM1

Project

Illumina Body Map 2, young vs old

Navigation

Downloads

Results for GCM1

Z-value: 2.17

Motif logo

Transcription factors associated with GCM1

Gene Symbol	Gene ID	Gene Info
GCM1 Ensembl NCBI GeneCards UniProt NextProt	ENSG00000137270.10	glial cells missing transcription factor 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
GCM1	hg19_v2_chr6_-_53013620_53013644	0.06	7.4e-01	Click!

Activity profile of GCM1 motif

Sorted Z-values of GCM1 motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr2_-_89630186 Show fit	5.22	ENST00000390264.2	IGKV2-40 Ensembl NCBI GeneCards UniProt NextProt Show fit	immunoglobulin kappa variable 2-40
chr22_+_22764088 Show fit	5.14	ENST00000390299.2	IGLV1-40 Ensembl NCBI GeneCards UniProt NextProt Show fit	immunoglobulin lambda variable 1-40
chr22_+_22786288 Show fit	5.13	ENST00000390301.2	IGLV1-36 Ensembl NCBI GeneCards UniProt NextProt Show fit	immunoglobulin lambda variable 1-36
chr22_+_22712087 Show fit	5.11	ENST00000390294.2	IGLV1-47 Ensembl NCBI GeneCards UniProt NextProt Show fit	immunoglobulin lambda variable 1-47
chr2_-_89385283 Show fit	4.84	ENST00000390252.2	IGKV3-15 Ensembl NCBI GeneCards UniProt NextProt Show fit	immunoglobulin kappa variable 3-15
chr22_+_23154239 Show fit	4.55	ENST00000390315.2	IGLV3-10 Ensembl NCBI GeneCards UniProt NextProt Show fit	immunoglobulin lambda variable 3-10
chr22_+_22676808 Show fit	4.51	ENST00000390290.2	IGLV1-51 Ensembl NCBI GeneCards UniProt NextProt Show fit	immunoglobulin lambda variable 1-51
chr2_+_208527094 Show fit	4.46	ENST00000429730.1	AC079767.4 Ensembl NCBI GeneCards UniProt NextProt Show fit	AC079767.4
chr22_+_23165153 Show fit	4.20	ENST00000390317.2	IGLV2-8 Ensembl NCBI GeneCards UniProt NextProt Show fit	immunoglobulin lambda variable 2-8
chr22_+_23077065 Show fit	3.79	ENST00000390310.2	IGLV2-18 Ensembl NCBI GeneCards UniProt NextProt Show fit	immunoglobulin lambda variable 2-18

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of GCM1

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	32.1	GO:0002377	immunoglobulin production(GO:0002377)
0.2	30.8	GO:0030449	regulation of complement activation(GO:0030449)
0.1	6.4	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0	5.2	GO:0002250	adaptive immune response(GO:0002250)
1.0	4.8	GO:0038043	interleukin-5-mediated signaling pathway(GO:0038043) interleukin-3-mediated signaling pathway(GO:0038156)
0.1	4.2	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.1	3.5	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.1	3.0	GO:0043029	T cell homeostasis(GO:0043029)
0.9	2.8	GO:1900075	regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.3	2.6	GO:0039663	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)

Showing 1 to 10 of 101 entries

Gene overrepresentation in cellular_component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	41.7	GO:0005615	extracellular space(GO:0005615)
0.0	8.0	GO:0072562	blood microparticle(GO:0072562)
0.2	6.4	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
1.6	4.8	GO:0030526	granulocyte macrophage colony-stimulating factor receptor complex(GO:0030526)
0.0	3.1	GO:0032587	ruffle membrane(GO:0032587)
0.2	2.8	GO:0099634	postsynaptic specialization membrane(GO:0099634)
0.0	2.5	GO:0031091	platelet alpha granule(GO:0031091)
0.3	2.4	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1	2.3	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	2.2	GO:0016235	aggresome(GO:0016235)

Showing 1 to 10 of 46 entries

Gene overrepresentation in molecular_function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	58.2	GO:0003823	antigen binding(GO:0003823)
0.5	6.4	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	5.6	GO:0005125	cytokine activity(GO:0005125)
1.0	4.8	GO:0004912	interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914)
0.0	3.5	GO:0004896	cytokine receptor activity(GO:0004896)
0.1	3.4	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.1	3.3	GO:0019992	diacylglycerol binding(GO:0019992)
0.2	2.6	GO:0032027	myosin light chain binding(GO:0032027)
0.8	2.4	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	2.4	GO:0042169	SH2 domain binding(GO:0042169)

Showing 1 to 10 of 70 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	6.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	6.3	PID AP1 PATHWAY	AP-1 transcription factor network
0.2	5.3	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	3.3	PID RAS PATHWAY	Regulation of Ras family activation
0.0	3.2	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	2.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	1.6	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	1.5	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	1.2	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	1.2	PID AURORA A PATHWAY	Aurora A signaling

Showing 1 to 10 of 21 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.3	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.1	3.9	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.4	2.6	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.2	2.4	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1	2.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	2.2	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.1	1.5	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	1.4	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	1.4	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	1.3	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex

Showing 1 to 10 of 34 entries

Results for GCM1

Z-value: 2.17

Motif logo

Transcription factors associated with GCM1

Activity-expression correlation:

Activity profile of GCM1 motif

Sorted Z-values of GCM1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of GCM1

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: