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Illumina Body Map 2, young vs old

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ISMARA results Illumina Body Map 2, young vs old

ISMARA - Integrated System for Motif Actitivity Response Analysis is a free online tool that recognizes most important transcription factors that are changing their activity in a set of samples.

Original results

Sample Condition
adipose.rep01 old
adipose.rep02 old
adrenal.rep01 old
adrenal.rep02 old
blood.rep01 old
blood.rep02 old
brain.rep01 old
brain.rep02 old
breast.rep01 young
breast.rep02 young
colon.rep01 old
colon.rep02 old
heart.rep01 old
heart.rep02 old
kidney.rep01 old
kidney.rep02 old
liver.rep01 young
liver.rep02 young
lung.rep01 old
lung.rep02 old
lymph.rep01 old
lymph.rep02 old
ovary.rep01 young
ovary.rep02 young
prostate.rep01 old
prostate.rep02 old
skeletal_muscle.rep01 old
skeletal_muscle.rep02 old
testes.rep01 young
testes.rep02 young
thyroid.rep01 old
thyroid.rep02 old

All motifs sorted by activity significance

Motif name Z-value Associated genes Profile Logo
MAFB 2.46 small profile SeqLogo of MAFB
ACAUUCA 2.41 small profile SeqLogo of ACAUUCA
GCM1 2.17 small profile SeqLogo of GCM1
ATF5 2.00 small profile SeqLogo of ATF5
NKX2-5 1.96 small profile SeqLogo of NKX2-5
TBX20 1.73 small profile SeqLogo of TBX20
NFKB1 1.67 small profile SeqLogo of NFKB1
KLF6 1.41 small profile SeqLogo of KLF6
DDIT3 1.40 small profile SeqLogo of DDIT3
GRHL1 1.36 small profile SeqLogo of GRHL1
ZBTB49 1.34 small profile SeqLogo of ZBTB49
ZBTB14 1.32 small profile SeqLogo of ZBTB14
EVX2 1.30 small profile SeqLogo of EVX2
NR1I2 1.29 small profile SeqLogo of NR1I2
JUND 1.28 small profile SeqLogo of JUND
NKX2-3 1.24 small profile SeqLogo of NKX2-3
HOXB8 1.23 small profile SeqLogo of HOXB8
SPIB 1.21 small profile SeqLogo of SPIB
FOXD3_FOXI1_FOXF1 1.20 small profile SeqLogo of FOXD3_FOXI1_FOXF1
MZF1 1.18 small profile SeqLogo of MZF1
TBX19 1.17 small profile SeqLogo of TBX19
ETS1 1.16 small profile SeqLogo of ETS1
EN1_ESX1_GBX1 1.14 small profile SeqLogo of EN1_ESX1_GBX1
MIXL1_GSX1_BSX_MEOX2_LHX4 1.14 small profile SeqLogo of MIXL1_GSX1_BSX_MEOX2_LHX4
ZBTB4 1.10 small profile SeqLogo of ZBTB4
TBX21_TBR1 1.09 small profile SeqLogo of TBX21_TBR1
MEIS1 1.05 small profile SeqLogo of MEIS1
UCACAGU 1.04 small profile SeqLogo of UCACAGU
RUNX3_BCL11A 1.03 small profile SeqLogo of RUNX3_BCL11A
DBX2_HLX 1.03 small profile SeqLogo of DBX2_HLX
TFAP4_MSC 1.00 small profile SeqLogo of TFAP4_MSC
EN2_GBX2_LBX2 0.95 small profile SeqLogo of EN2_GBX2_LBX2
ZNF384 0.95 small profile SeqLogo of ZNF384
ZSCAN4 0.95 small profile SeqLogo of ZSCAN4
NR2E1 0.94 small profile SeqLogo of NR2E1
PAX7_NOBOX 0.94 small profile SeqLogo of PAX7_NOBOX
OLIG2_NEUROD1_ATOH1 0.93 small profile SeqLogo of OLIG2_NEUROD1_ATOH1
TWIST1_SNAI1 0.93 small profile SeqLogo of TWIST1_SNAI1
FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 0.91 small profile SeqLogo of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1
PPARA 0.88 small profile SeqLogo of PPARA
CPEB1 0.88 small profile SeqLogo of CPEB1
ELF3_EHF 0.87 small profile SeqLogo of ELF3_EHF
CAGUGCA 0.87 small profile SeqLogo of CAGUGCA
TBX3 0.86 small profile SeqLogo of TBX3
TBX5 0.85 small profile SeqLogo of TBX5
HOXB6_PRRX2 0.85 small profile SeqLogo of HOXB6_PRRX2
FOXN1 0.84 small profile SeqLogo of FOXN1
NR4A2 0.84 small profile SeqLogo of NR4A2
GGCAGUG 0.82 small profile SeqLogo of GGCAGUG
ZNF282 0.82 small profile SeqLogo of ZNF282
ACAGUAC 0.82 small profile SeqLogo of ACAGUAC
CACAGUG 0.80 small profile SeqLogo of CACAGUG
ATF6 0.80 small profile SeqLogo of ATF6
FLI1 0.80 small profile SeqLogo of FLI1
SOX8 0.79 small profile SeqLogo of SOX8
AGUGCUU 0.78 small profile SeqLogo of AGUGCUU
ETV1_ERF_FEV_ELF1 0.77 small profile SeqLogo of ETV1_ERF_FEV_ELF1
CREB3L1_CREB3 0.76 small profile SeqLogo of CREB3L1_CREB3
UACAGUA 0.76 small profile SeqLogo of UACAGUA
ERG 0.76 small profile SeqLogo of ERG
AUGGCUU 0.75 small profile SeqLogo of AUGGCUU
FOXO4 0.75 small profile SeqLogo of FOXO4
RHOXF1 0.74 small profile SeqLogo of RHOXF1
MAFA 0.73 small profile SeqLogo of MAFA
NKX2-1 0.73 small profile SeqLogo of NKX2-1
ISX 0.73 small profile SeqLogo of ISX
NR1I3 0.72 small profile SeqLogo of NR1I3
STAT4 0.71 small profile SeqLogo of STAT4
KLF16_SP2 0.71 small profile SeqLogo of KLF16_SP2
RORC 0.71 small profile SeqLogo of RORC
UUGGUCC 0.70 small profile SeqLogo of UUGGUCC
NFIX_NFIB 0.69 small profile SeqLogo of NFIX_NFIB
SPI1 0.69 small profile SeqLogo of SPI1
HMBOX1 0.68 small profile SeqLogo of HMBOX1
SP4_PML 0.68 small profile SeqLogo of SP4_PML
JDP2 0.66 small profile SeqLogo of JDP2
SMAD4 0.65 small profile SeqLogo of SMAD4
UAUUGCU 0.64 small profile SeqLogo of UAUUGCU
HOXC11 0.64 small profile SeqLogo of HOXC11
PAX1_PAX9 0.64 small profile SeqLogo of PAX1_PAX9
KLF15 0.64 small profile SeqLogo of KLF15
DLX1_HOXA3_BARX2 0.63 small profile SeqLogo of DLX1_HOXA3_BARX2
POU5F1_POU2F3 0.63 small profile SeqLogo of POU5F1_POU2F3
OTX2_CRX 0.63 small profile SeqLogo of OTX2_CRX
HOXA6 0.61 small profile SeqLogo of HOXA6
ETV7 0.61 small profile SeqLogo of ETV7
TBX15_MGA 0.61 small profile SeqLogo of TBX15_MGA
ARID5B 0.61 small profile SeqLogo of ARID5B
FIGLA 0.60 small profile SeqLogo of FIGLA
RFX5 0.60 small profile SeqLogo of RFX5
CCCUGAG 0.60 small profile SeqLogo of CCCUGAG
ATF4 0.60 small profile SeqLogo of ATF4
ZNF652 0.59 small profile SeqLogo of ZNF652
THRA_RXRB 0.59 small profile SeqLogo of THRA_RXRB
HNF4G 0.58 small profile SeqLogo of HNF4G
UBP1 0.58 small profile SeqLogo of UBP1
HOXA9 0.58 small profile SeqLogo of HOXA9
MLX_USF2_USF1_PAX2 0.57 small profile SeqLogo of MLX_USF2_USF1_PAX2
PROX1 0.57 small profile SeqLogo of PROX1
SOX13_SOX12 0.57 small profile SeqLogo of SOX13_SOX12
MYB 0.57 small profile SeqLogo of MYB
KLF1 0.57 small profile SeqLogo of KLF1
BACH2 0.57 small profile SeqLogo of BACH2
ARID3A 0.56 small profile SeqLogo of ARID3A
NKX2-6 0.56 small profile SeqLogo of NKX2-6
CXXC1 0.55 small profile SeqLogo of CXXC1
TCF7L2 0.55 small profile SeqLogo of TCF7L2
AAAGUGC 0.55 small profile SeqLogo of AAAGUGC
SP100 0.55 small profile SeqLogo of SP100
MEIS3_TGIF2LX 0.55 small profile SeqLogo of MEIS3_TGIF2LX
WRNIP1 0.54 small profile SeqLogo of WRNIP1
PBX3 0.54 small profile SeqLogo of PBX3
ESRRB_ESRRG 0.54 small profile SeqLogo of ESRRB_ESRRG
BARHL2 0.54 small profile SeqLogo of BARHL2
PAX5 0.54 small profile SeqLogo of PAX5
HOXB3 0.53 small profile SeqLogo of HOXB3
MEIS2 0.53 small profile SeqLogo of MEIS2
T 0.53 small profile SeqLogo of T
LHX2 0.53 small profile SeqLogo of LHX2
DLX3_EVX1_MEOX1 0.52 small profile SeqLogo of DLX3_EVX1_MEOX1
POU4F2 0.52 small profile SeqLogo of POU4F2
TCF12_ASCL2 0.52 small profile SeqLogo of TCF12_ASCL2
IKZF1 0.52 small profile SeqLogo of IKZF1
SOX21 0.51 small profile SeqLogo of SOX21
HMGA2 0.51 small profile SeqLogo of HMGA2
TFAP2C 0.50 small profile SeqLogo of TFAP2C
TFEC_MITF_ARNTL_BHLHE41 0.50 small profile SeqLogo of TFEC_MITF_ARNTL_BHLHE41
CBFB 0.50 small profile SeqLogo of CBFB
ZBTB3 0.50 small profile SeqLogo of ZBTB3
TEAD4 0.50 small profile SeqLogo of TEAD4
NOTO_VSX2_DLX2_DLX6_NKX6-1 0.50 small profile SeqLogo of NOTO_VSX2_DLX2_DLX6_NKX6-1
GGAAGAC 0.49 small profile SeqLogo of GGAAGAC
DMC1 0.49 small profile SeqLogo of DMC1
VAX2_RHOXF2 0.49 small profile SeqLogo of VAX2_RHOXF2
DMBX1 0.48 small profile SeqLogo of DMBX1
LEF1 0.48 small profile SeqLogo of LEF1
ONECUT1 0.48 small profile SeqLogo of ONECUT1
SPDEF 0.48 small profile SeqLogo of SPDEF
IRX3 0.48 small profile SeqLogo of IRX3
HOXD4 0.47 small profile SeqLogo of HOXD4
MBD2 0.47 small profile SeqLogo of MBD2
TFAP2B 0.47 small profile SeqLogo of TFAP2B
PPARD 0.47 small profile SeqLogo of PPARD
GLIS2 0.47 small profile SeqLogo of GLIS2
AUAAAGU 0.46 small profile SeqLogo of AUAAAGU
MYOD1 0.46 small profile SeqLogo of MYOD1
MXI1_MYC_MYCN 0.46 small profile SeqLogo of MXI1_MYC_MYCN
LHX6 0.46 small profile SeqLogo of LHX6
SOX7 0.46 small profile SeqLogo of SOX7
ZNF232 0.46 small profile SeqLogo of ZNF232
STAT5B 0.46 small profile SeqLogo of STAT5B
GUGCAAA 0.46 small profile SeqLogo of GUGCAAA
AGUGCAA 0.46 small profile SeqLogo of AGUGCAA
NR1D1 0.46 small profile SeqLogo of NR1D1
ZNF350 0.45 small profile SeqLogo of ZNF350
ISL2 0.45 small profile SeqLogo of ISL2
GFI1 0.45 small profile SeqLogo of GFI1
SOX10_SOX15 0.45 small profile SeqLogo of SOX10_SOX15
NFIA 0.44 small profile SeqLogo of NFIA
UGCAUAG 0.44 small profile SeqLogo of UGCAUAG
HOXA5 0.44 small profile SeqLogo of HOXA5
BARX1 0.44 small profile SeqLogo of BARX1
UGGUCCC 0.43 small profile SeqLogo of UGGUCCC
PRDM4 0.43 small profile SeqLogo of PRDM4
JUN 0.43 small profile SeqLogo of JUN
MYBL2 0.43 small profile SeqLogo of MYBL2
GCM2 0.43 small profile SeqLogo of GCM2
AAUCUCU 0.43 small profile SeqLogo of AAUCUCU
NR2E3 0.43 small profile SeqLogo of NR2E3
AUUGCAC 0.43 small profile SeqLogo of AUUGCAC
ATF2_ATF1_ATF3 0.42 small profile SeqLogo of ATF2_ATF1_ATF3
UGGCACU 0.42
small profile
GUCAGUU 0.42 small profile SeqLogo of GUCAGUU
GUAAACA 0.42 small profile SeqLogo of GUAAACA
BBX 0.42 small profile SeqLogo of BBX
FOXA1 0.41 small profile SeqLogo of FOXA1
HNF1A_HNF1B 0.41 small profile SeqLogo of HNF1A_HNF1B
SP1 0.41 small profile SeqLogo of SP1
NFATC2_NFATC3 0.41 small profile SeqLogo of NFATC2_NFATC3
GAUUGUC 0.41 small profile SeqLogo of GAUUGUC
HBP1 0.41 small profile SeqLogo of HBP1
HNF4A 0.41 small profile SeqLogo of HNF4A
GAGGUAG 0.40 small profile SeqLogo of GAGGUAG
RELA 0.40 small profile SeqLogo of RELA
SIX5_SMARCC2_HCFC1 0.40 small profile SeqLogo of SIX5_SMARCC2_HCFC1
VDR 0.40 small profile SeqLogo of VDR
ZFX 0.40 small profile SeqLogo of ZFX
BCL6B 0.39 small profile SeqLogo of BCL6B
PITX1 0.39 small profile SeqLogo of PITX1
ONECUT2_ONECUT3 0.39 small profile SeqLogo of ONECUT2_ONECUT3
MNT_HEY1_HEY2 0.39 small profile SeqLogo of MNT_HEY1_HEY2
GUAACAG 0.39 small profile SeqLogo of GUAACAG
CUUUGGU 0.39 small profile SeqLogo of CUUUGGU
TFDP1 0.39 small profile SeqLogo of TFDP1
HES1 0.39 small profile SeqLogo of HES1
HOXC10_HOXD13 0.39 small profile SeqLogo of HOXC10_HOXD13
CREB3L2 0.39 small profile SeqLogo of CREB3L2
EBF3 0.39 small profile SeqLogo of EBF3
MAFF_MAFG 0.39 small profile SeqLogo of MAFF_MAFG
NR2C1 0.39 small profile SeqLogo of NR2C1
NKX2-2 0.39 small profile SeqLogo of NKX2-2
NR6A1 0.39 small profile SeqLogo of NR6A1
FOXA3_FOXC2 0.38 small profile SeqLogo of FOXA3_FOXC2
CENPB 0.38 small profile SeqLogo of CENPB
YY1_YY2 0.38 small profile SeqLogo of YY1_YY2
NKX1-2_RAX 0.38 small profile SeqLogo of NKX1-2_RAX
GLI2 0.38 small profile SeqLogo of GLI2
TBP 0.38 small profile SeqLogo of TBP
PAX4 0.38 small profile SeqLogo of PAX4
SHOX2_HOXC5 0.38 small profile SeqLogo of SHOX2_HOXC5
ATF7 0.37 small profile SeqLogo of ATF7
TBX4 0.37 small profile SeqLogo of TBX4
GCCUGUC 0.37 small profile SeqLogo of GCCUGUC
IRX5 0.37 small profile SeqLogo of IRX5
EGR1_EGR4 0.37 small profile SeqLogo of EGR1_EGR4
AAUGCCC 0.37 small profile SeqLogo of AAUGCCC
SRY 0.37 small profile SeqLogo of SRY
VAX1_GSX2 0.37 small profile SeqLogo of VAX1_GSX2
HOXB5 0.37 small profile SeqLogo of HOXB5
UUGUUCG 0.37 small profile SeqLogo of UUGUUCG
IRX6_IRX4 0.37 small profile SeqLogo of IRX6_IRX4
PBX1 0.36 small profile SeqLogo of PBX1
REL 0.36 small profile SeqLogo of REL
SOX18 0.36 small profile SeqLogo of SOX18
ACCACAG 0.36 small profile SeqLogo of ACCACAG
MAFK 0.36 small profile SeqLogo of MAFK
YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ 0.36 small profile SeqLogo of YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ
IRF2_STAT2_IRF8_IRF1 0.36 small profile SeqLogo of IRF2_STAT2_IRF8_IRF1
HOXA4 0.36 small profile SeqLogo of HOXA4
EZH2 0.36 small profile SeqLogo of EZH2
NKX2-8 0.35 small profile SeqLogo of NKX2-8
NFATC1 0.35 small profile SeqLogo of NFATC1
BHLHE40 0.35 small profile SeqLogo of BHLHE40
MECP2 0.35 small profile SeqLogo of MECP2
IRF3 0.35 small profile SeqLogo of IRF3
RFX7_RFX4_RFX1 0.35 small profile SeqLogo of RFX7_RFX4_RFX1
RELB 0.35 small profile SeqLogo of RELB
POU3F2 0.35 small profile SeqLogo of POU3F2
ZNF148 0.35 small profile SeqLogo of ZNF148
MEF2C 0.35 small profile SeqLogo of MEF2C
MESP1 0.34 small profile SeqLogo of MESP1
TP53 0.34 small profile SeqLogo of TP53
HSFY2 0.34 small profile SeqLogo of HSFY2
TLX2 0.34 small profile SeqLogo of TLX2
EGR3_EGR2 0.34 small profile SeqLogo of EGR3_EGR2
ETV2 0.34 small profile SeqLogo of ETV2
SMAD2 0.34 small profile SeqLogo of SMAD2
SIX1_SIX3_SIX2 0.34 small profile SeqLogo of SIX1_SIX3_SIX2
CCAGUGU 0.33 small profile SeqLogo of CCAGUGU
FOXK1_FOXP2_FOXB1_FOXP3 0.33 small profile SeqLogo of FOXK1_FOXP2_FOXB1_FOXP3
UAAUGCU 0.33 small profile SeqLogo of UAAUGCU
AR_NR3C2 0.33 small profile SeqLogo of AR_NR3C2
E2F6 0.33 small profile SeqLogo of E2F6
OVOL1 0.33 small profile SeqLogo of OVOL1
FOXM1_TBL1XR1 0.33 small profile SeqLogo of FOXM1_TBL1XR1
SOX30 0.33 small profile SeqLogo of SOX30
HOXA1 0.33 small profile SeqLogo of HOXA1
NFAT5 0.32 small profile SeqLogo of NFAT5
SIX6 0.32 small profile SeqLogo of SIX6
FOSL1 0.32 small profile SeqLogo of FOSL1
ZNF143 0.32 small profile SeqLogo of ZNF143
GSC_GSC2 0.31 small profile SeqLogo of GSC_GSC2
UAAGACG 0.31 small profile SeqLogo of UAAGACG
AGCACCA 0.31 small profile SeqLogo of AGCACCA
NR4A1 0.31 small profile SeqLogo of NR4A1
ZFHX3 0.31 small profile SeqLogo of ZFHX3
FUBP1 0.31 small profile SeqLogo of FUBP1
ZNF8 0.31 small profile SeqLogo of ZNF8
NR4A3 0.31 small profile SeqLogo of NR4A3
CUX1 0.31 small profile SeqLogo of CUX1
HINFP1 0.30
small profile SeqLogo of HINFP1
NR5A2 0.30 small profile SeqLogo of NR5A2
SOX9 0.30 small profile SeqLogo of SOX9
ELF2_GABPA_ELF5 0.30 small profile SeqLogo of ELF2_GABPA_ELF5
HSF1 0.30 small profile SeqLogo of HSF1
AACAGUC 0.29 small profile SeqLogo of AACAGUC
PGR 0.29 small profile SeqLogo of PGR
ZNF524 0.29 small profile SeqLogo of ZNF524
AAGUGCU 0.29 small profile SeqLogo of AAGUGCU
SOX11 0.29 small profile SeqLogo of SOX11
CEBPG 0.29 small profile SeqLogo of CEBPG
UAAGACU 0.29 small profile SeqLogo of UAAGACU
RFX3_RFX2 0.29 small profile SeqLogo of RFX3_RFX2
OTP_PHOX2B_LHX1_LMX1A_LHX5_HOXC4 0.29 small profile SeqLogo of OTP_PHOX2B_LHX1_LMX1A_LHX5_HOXC4
FOXA2_FOXJ3 0.29 small profile SeqLogo of FOXA2_FOXJ3
ESRRA_ESR2 0.28 small profile SeqLogo of ESRRA_ESR2
SOX1 0.28 small profile SeqLogo of SOX1
HIC1 0.28 small profile SeqLogo of HIC1
HDX 0.28 small profile SeqLogo of HDX
UAAGGCA 0.28 small profile SeqLogo of UAAGGCA
RBPJ 0.28 small profile SeqLogo of RBPJ
RAD21_SMC3 0.28 small profile SeqLogo of RAD21_SMC3
STAT6 0.28 small profile SeqLogo of STAT6
NR2F1 0.28 small profile SeqLogo of NR2F1
REST 0.28 small profile SeqLogo of REST
PDX1 0.28 small profile SeqLogo of PDX1
CUGGCUG 0.28 small profile SeqLogo of CUGGCUG
UGAAAUG 0.28
small profile
POU2F2_POU3F1 0.28 small profile SeqLogo of POU2F2_POU3F1
TAF1 0.28 small profile SeqLogo of TAF1
UGACCUA 0.28 small profile SeqLogo of UGACCUA
KLF13 0.28 small profile SeqLogo of KLF13
FOXO3_FOXD2 0.27 small profile SeqLogo of FOXO3_FOXD2
SOX14 0.27 small profile SeqLogo of SOX14
TCF7L1 0.27 small profile SeqLogo of TCF7L1
BATF3 0.27 small profile SeqLogo of BATF3
ZBTB18 0.27