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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for CCCUGAG
Z-value: 1.51
Motif logo
miRNA associated with seed CCCUGAG
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chrX_+_64708615 Show fit | 37.28 |
ENST00000338957.4
ENST00000423889.3 |
zinc finger CCCH-type containing 12B |
|
| chr15_+_31619013 Show fit | 30.24 |
ENST00000307145.3
|
Kruppel-like factor 13 |
|
| chr22_-_39548627 Show fit | 23.17 |
ENST00000216133.5
|
chromobox homolog 7 |
|
| chr15_+_74833518 Show fit | 21.55 |
ENST00000346246.5
|
AT rich interactive domain 3B (BRIGHT-like) |
|
| chr9_-_116102530 Show fit | 21.04 |
ENST00000374195.3
ENST00000341761.4 |
WD repeat domain 31 |
|
| chrX_-_103401649 Show fit | 20.71 |
ENST00000357421.4
|
solute carrier family 25, member 53 |
|
| chr4_-_2264015 Show fit | 18.86 |
ENST00000337190.2
|
MAX dimerization protein 4 |
|
| chr2_-_206950781 Show fit | 18.74 |
ENST00000403263.1
|
INO80 complex subunit D |
|
| chr17_-_61777459 Show fit | 18.59 |
ENST00000578993.1
ENST00000583211.1 ENST00000259006.3 |
LIM domain containing 2 |
|
| chr19_+_7968728 Show fit | 17.92 |
ENST00000397981.3
ENST00000545011.1 ENST00000397983.3 ENST00000397979.3 |
mitogen-activated protein kinase kinase 7 |
Network of associatons between targets according to the STRING database.
First level regulatory network of CCCUGAG
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.0 | 30.2 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
| 3.9 | 19.4 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
| 2.2 | 17.9 | GO:0035897 | proteolysis in other organism(GO:0035897) |
| 0.1 | 17.6 | GO:0090305 | nucleic acid phosphodiester bond hydrolysis(GO:0090305) |
| 1.6 | 17.4 | GO:2000049 | positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049) |
| 0.1 | 16.3 | GO:0007601 | visual perception(GO:0007601) |
| 5.1 | 15.3 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
| 3.8 | 15.1 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 0.4 | 14.7 | GO:0034035 | purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) |
| 0.7 | 14.1 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 38.4 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.2 | 34.4 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.1 | 30.2 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.2 | 28.5 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
| 0.2 | 27.0 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 25.2 | GO:0016604 | nuclear body(GO:0016604) |
| 0.3 | 23.9 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 1.7 | 23.2 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.1 | 19.6 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.1 | 16.6 | GO:0031965 | nuclear membrane(GO:0031965) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 36.1 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 1.1 | 30.5 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.1 | 28.7 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.2 | 25.7 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.4 | 21.6 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.4 | 18.9 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.8 | 18.7 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.1 | 18.4 | GO:0004519 | endonuclease activity(GO:0004519) |
| 0.2 | 17.4 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
| 0.3 | 17.2 | GO:0035254 | glutamate receptor binding(GO:0035254) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 56.6 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.1 | 37.8 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.3 | 15.5 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.1 | 15.3 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.2 | 14.9 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.1 | 14.8 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.1 | 14.8 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.4 | 14.4 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.3 | 14.1 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.3 | 12.4 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 25.9 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.8 | 23.6 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.9 | 19.3 | REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.5 | 18.9 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.2 | 18.0 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
| 0.2 | 17.5 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.3 | 15.1 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.1 | 14.9 | REACTOME G ALPHA Q SIGNALLING EVENTS | Genes involved in G alpha (q) signalling events |
| 0.2 | 12.9 | REACTOME POTASSIUM CHANNELS | Genes involved in Potassium Channels |
| 0.5 | 12.8 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |