Project

GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

Navigation
Downloads

Results for HOXC8

Z-value: 1.25

Motif logo

Transcription factors associated with HOXC8

Gene Symbol Gene ID Gene Info
ENSG00000037965.4 homeobox C8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXC8hg19_v2_chr12_+_54402790_54402832-0.341.8e-07Click!

Activity profile of HOXC8 motif

Sorted Z-values of HOXC8 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_109590174 24.44 ENST00000372054.1
guanine nucleotide binding protein (G protein), gamma 5 pseudogene 2
chr8_-_27695552 22.95 ENST00000522944.1
ENST00000301905.4
PDZ binding kinase
chrX_+_119737806 18.79 ENST00000371317.5
malignant T cell amplified sequence 1
chr3_-_64009658 15.72 ENST00000394431.2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr18_+_657578 15.41 ENST00000323274.10
thymidylate synthetase
chr16_-_46655538 15.26 ENST00000303383.3
SHC SH2-domain binding protein 1
chr5_+_159848854 14.55 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
pituitary tumor-transforming 1
chr2_-_89292422 13.81 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr2_+_89890533 13.37 ENST00000429992.2
immunoglobulin kappa variable 2D-40
chr5_+_135385202 13.28 ENST00000514554.1
transforming growth factor, beta-induced, 68kDa
chr2_-_89513402 13.23 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr1_+_45205478 12.73 ENST00000452259.1
ENST00000372224.4
kinesin family member 2C
chr7_-_105752971 12.52 ENST00000011473.2
synaptophysin-like 1
chr10_+_62538089 12.47 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
cyclin-dependent kinase 1
chr12_-_102455846 12.33 ENST00000545679.1
coiled-coil domain containing 53
chr2_-_150444116 12.13 ENST00000428879.1
ENST00000422782.2
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr2_+_187371440 11.88 ENST00000445547.1
zinc finger CCCH-type containing 15
chr7_-_6523688 11.83 ENST00000490996.1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr1_-_149900122 11.52 ENST00000271628.8
splicing factor 3b, subunit 4, 49kDa
chr15_-_59949693 11.46 ENST00000396063.1
ENST00000396064.3
ENST00000484743.1
ENST00000559706.1
ENST00000396060.2
general transcription factor IIA, 2, 12kDa
chr9_+_134065506 11.34 ENST00000483497.2
nucleoporin 214kDa
chr15_-_59949667 11.13 ENST00000396061.1
general transcription factor IIA, 2, 12kDa
chr22_+_42017987 11.01 ENST00000405506.1
X-ray repair complementing defective repair in Chinese hamster cells 6
chr1_-_225615599 10.91 ENST00000421383.1
ENST00000272163.4
lamin B receptor
chr12_-_54652060 10.83 ENST00000552562.1
chromobox homolog 5
chr1_+_45205498 10.78 ENST00000372218.4
kinesin family member 2C
chr5_+_172385732 10.77 ENST00000519974.1
ENST00000521476.1
ribosomal protein L26-like 1
chr2_+_90139056 10.61 ENST00000492446.1
immunoglobulin kappa variable 1D-16
chr2_-_89521942 10.55 ENST00000482769.1
immunoglobulin kappa variable 2-28
chr10_+_62538248 10.30 ENST00000448257.2
cyclin-dependent kinase 1
chr4_+_79472673 10.23 ENST00000264908.6
annexin A3
chr5_+_167913450 10.12 ENST00000231572.3
ENST00000538719.1
arginyl-tRNA synthetase
chr10_+_5135981 10.11 ENST00000380554.3
aldo-keto reductase family 1, member C3
chr15_+_59397275 9.93 ENST00000288207.2
cyclin B2
chr2_-_89568263 9.84 ENST00000473726.1
immunoglobulin kappa variable 1-33
chr11_+_35198118 9.80 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
CD44 molecule (Indian blood group)
chr1_+_226250379 9.67 ENST00000366815.3
ENST00000366814.3
H3 histone, family 3A
chr7_-_132766818 9.54 ENST00000262570.5
coiled-coil-helix-coiled-coil-helix domain containing 3
chr7_-_132766800 9.54 ENST00000542753.1
ENST00000448878.1
coiled-coil-helix-coiled-coil-helix domain containing 3
chr5_-_68665084 9.42 ENST00000509462.1
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chrX_-_38080077 9.33 ENST00000378533.3
ENST00000544439.1
ENST00000432886.2
ENST00000538295.1
sushi-repeat containing protein, X-linked
chr1_-_146040968 9.32 ENST00000401010.3
neuroblastoma breakpoint family, member 11
chr14_-_107083690 9.23 ENST00000455737.1
ENST00000390629.2
immunoglobulin heavy variable 4-59
chr2_+_90108504 9.21 ENST00000390271.2
immunoglobulin kappa variable 6D-41 (non-functional)
chr3_-_149095652 9.01 ENST00000305366.3
transmembrane 4 L six family member 1
chr6_+_63921399 9.00 ENST00000356170.3
FK506 binding protein 1C
chr6_+_27114861 8.92 ENST00000377459.1
histone cluster 1, H2ah
chr14_-_106642049 8.84 ENST00000390605.2
immunoglobulin heavy variable 1-18
chr12_+_21525818 8.78 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
islet amyloid polypeptide
chr10_-_58120996 8.59 ENST00000361148.6
ENST00000395405.1
ENST00000373944.3
ZW10 interacting kinetochore protein
chr13_+_34392185 8.49 ENST00000380071.3
replication factor C (activator 1) 3, 38kDa
chr3_-_141719195 8.43 ENST00000397991.4
transcription factor Dp-2 (E2F dimerization partner 2)
chr2_-_176046391 8.34 ENST00000392541.3
ENST00000409194.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr16_-_24942411 8.32 ENST00000571843.1
Rho GTPase activating protein 17
chr11_+_60223225 8.27 ENST00000524807.1
ENST00000345732.4
membrane-spanning 4-domains, subfamily A, member 1
chrX_+_48433326 8.23 ENST00000376755.1
RNA binding motif (RNP1, RRM) protein 3
chr19_-_10697895 7.88 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
adaptor-related protein complex 1, mu 2 subunit
chr16_-_24942273 7.85 ENST00000571406.1
Rho GTPase activating protein 17
chr12_+_75874580 7.80 ENST00000456650.3
GLI pathogenesis-related 1
chr12_-_53320245 7.60 ENST00000552150.1
keratin 8
chr18_+_3252265 7.57 ENST00000580887.1
ENST00000536605.1
myosin, light chain 12A, regulatory, non-sarcomeric
chr5_+_110074685 7.53 ENST00000355943.3
ENST00000447245.2
solute carrier family 25, member 46
chr2_-_70520539 7.50 ENST00000482975.2
ENST00000438261.1
small nuclear ribonucleoprotein polypeptide G
chr7_-_87856280 7.42 ENST00000490437.1
ENST00000431660.1
sorcin
chr2_+_192109911 7.40 ENST00000418908.1
ENST00000339514.4
ENST00000392318.3
myosin IB
chr6_-_27114577 7.29 ENST00000356950.1
ENST00000396891.4
histone cluster 1, H2bk
chr14_-_75643296 7.29 ENST00000303575.4
transmembrane emp24-like trafficking protein 10 (yeast)
chr22_+_23063100 7.28 ENST00000390309.2
immunoglobulin lambda variable 3-19
chr13_+_53216565 7.27 ENST00000357495.2
heterogeneous nuclear ribonucleoprotein A1-like 2
chr2_-_70520832 7.25 ENST00000454893.1
ENST00000272348.2
small nuclear ribonucleoprotein polypeptide G
chr2_+_216176540 7.23 ENST00000236959.9
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr1_+_53480598 7.16 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
sterol carrier protein 2
chr3_-_64009102 7.12 ENST00000478185.1
ENST00000482510.1
ENST00000497323.1
ENST00000492933.1
ENST00000295901.4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr14_-_58894223 7.11 ENST00000555593.1
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr14_-_106733624 7.09 ENST00000390610.2
immunoglobulin heavy variable 1-24
chr12_+_104609550 7.08 ENST00000525566.1
ENST00000429002.2
thioredoxin reductase 1
chr7_-_87856303 7.07 ENST00000394641.3
sorcin
chr8_-_101718991 7.04 ENST00000517990.1
poly(A) binding protein, cytoplasmic 1
chr12_-_102455902 7.03 ENST00000240079.6
coiled-coil domain containing 53
chr6_-_159065741 7.00 ENST00000367085.3
ENST00000367089.3
dynein, light chain, Tctex-type 1
chr2_-_20251744 6.99 ENST00000175091.4
lysosomal protein transmembrane 4 alpha
chr2_-_89310012 6.94 ENST00000493819.1
immunoglobulin kappa variable 1-9
chr17_-_8113542 6.91 ENST00000578549.1
ENST00000535053.1
ENST00000582368.1
aurora kinase B
chr1_+_224544572 6.90 ENST00000366857.5
ENST00000366856.3
cornichon family AMPA receptor auxiliary protein 4
chr4_+_169418195 6.90 ENST00000261509.6
ENST00000335742.7
palladin, cytoskeletal associated protein
chr8_-_101962777 6.87 ENST00000395951.3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr2_-_24308051 6.84 ENST00000238721.4
ENST00000335934.4
tumor protein p53 inducible protein 3
chr1_-_40042416 6.80 ENST00000372857.3
ENST00000372856.3
ENST00000531243.2
ENST00000451091.2
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr6_+_57037089 6.78 ENST00000370693.5
BCL2-associated athanogene 2
chr14_+_89060739 6.72 ENST00000318308.6
zinc finger CCCH-type containing 14
chr14_-_106322288 6.69 ENST00000390559.2
immunoglobulin heavy constant mu
chr4_+_83956237 6.69 ENST00000264389.2
COP9 signalosome subunit 4
chr15_+_66797627 6.68 ENST00000565627.1
ENST00000564179.1
zwilch kinetochore protein
chr2_-_89247338 6.68 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr2_+_178257372 6.67 ENST00000264167.4
ENST00000409888.1
alkylglycerone phosphate synthase
chr2_-_106054952 6.67 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
four and a half LIM domains 2
chr1_+_165864821 6.66 ENST00000470820.1
uridine-cytidine kinase 2
chr14_-_106926724 6.65 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr10_+_94352956 6.61 ENST00000260731.3
kinesin family member 11
chr14_+_89060749 6.54 ENST00000555900.1
ENST00000406216.3
ENST00000557737.1
zinc finger CCCH-type containing 14
chr14_-_106878083 6.52 ENST00000390619.2
immunoglobulin heavy variable 4-39
chr11_+_60223312 6.51 ENST00000532491.1
ENST00000532073.1
ENST00000534668.1
ENST00000528313.1
ENST00000533306.1
membrane-spanning 4-domains, subfamily A, member 1
chr1_+_33116765 6.49 ENST00000544435.1
ENST00000373485.1
ENST00000458695.2
ENST00000490500.1
ENST00000445722.2
retinoblastoma binding protein 4
chr11_+_35198243 6.44 ENST00000528455.1
CD44 molecule (Indian blood group)
chr14_+_20937538 6.41 ENST00000361505.5
ENST00000553591.1
purine nucleoside phosphorylase
chr12_-_10875831 6.32 ENST00000279550.7
ENST00000228251.4
Y box binding protein 3
chr12_-_65146636 6.31 ENST00000418919.2
glucosamine (N-acetyl)-6-sulfatase
chr17_-_55038375 6.30 ENST00000240316.4
coilin
chr10_+_13652047 6.29 ENST00000601460.1
Uncharacterized protein
chr4_+_69962212 6.27 ENST00000508661.1
UDP glucuronosyltransferase 2 family, polypeptide B7
chr8_+_104310661 6.26 ENST00000522566.1
frizzled family receptor 6
chr17_-_40288449 6.21 ENST00000552162.1
ENST00000550504.1
RAB5C, member RAS oncogene family
chr19_+_49496705 6.17 ENST00000595090.1
RuvB-like AAA ATPase 2
chr12_+_96252706 6.16 ENST00000266735.5
ENST00000553192.1
ENST00000552085.1
small nuclear ribonucleoprotein polypeptide F
chr2_-_89459813 6.14 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr20_+_1099233 6.11 ENST00000246015.4
ENST00000335877.6
ENST00000438768.2
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chrX_-_16887963 6.11 ENST00000380084.4
retinoblastoma binding protein 7
chr14_-_106781017 6.09 ENST00000390612.2
immunoglobulin heavy variable 4-28
chr2_+_102456277 6.06 ENST00000421882.1
mitogen-activated protein kinase kinase kinase kinase 4
chr14_-_106406090 6.04 ENST00000390593.2
immunoglobulin heavy variable 6-1
chr15_-_59225758 5.98 ENST00000558486.1
ENST00000560682.1
ENST00000249736.7
ENST00000559880.1
ENST00000536328.1
SAFB-like, transcription modulator
chr1_+_144173162 5.97 ENST00000356801.6
neuroblastoma breakpoint family, member 8
chr3_+_151986709 5.97 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
muscleblind-like splicing regulator 1
chr11_+_101983176 5.97 ENST00000524575.1
Yes-associated protein 1
chr5_-_68665296 5.96 ENST00000512152.1
ENST00000503245.1
ENST00000512561.1
ENST00000380822.4
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr6_-_34393825 5.95 ENST00000605528.1
ENST00000326199.8
RPS10-NUDT3 readthrough
ribosomal protein S10
chr3_-_81811312 5.92 ENST00000429644.2
glucan (1,4-alpha-), branching enzyme 1
chr10_+_79793518 5.90 ENST00000440692.1
ENST00000435275.1
ENST00000372360.3
ENST00000360830.4
ribosomal protein S24
chr8_-_101719159 5.86 ENST00000520868.1
ENST00000522658.1
poly(A) binding protein, cytoplasmic 1
chr3_-_189840223 5.83 ENST00000427335.2
leprecan-like 1
chr12_+_117013656 5.83 ENST00000556529.1
microtubule-associated protein 1 light chain 3 beta 2
chr5_+_34757309 5.83 ENST00000397449.1
retinoic acid induced 14
chr2_-_89399845 5.80 ENST00000479981.1
immunoglobulin kappa variable 1-16
chr22_-_36924944 5.78 ENST00000405442.1
ENST00000402116.1
eukaryotic translation initiation factor 3, subunit D
chr2_+_90153696 5.78 ENST00000417279.2
immunoglobulin kappa variable 3D-15 (gene/pseudogene)
chr9_-_32573130 5.78 ENST00000350021.2
ENST00000379847.3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
chr6_+_24667257 5.75 ENST00000537591.1
ENST00000230048.4
acyl-CoA thioesterase 13
chr14_-_106478603 5.68 ENST00000390596.2
immunoglobulin heavy variable 4-4
chr4_-_71532339 5.68 ENST00000254801.4
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr15_-_101835110 5.68 ENST00000560496.1
small nuclear ribonucleoprotein polypeptide A'
chr17_-_38574169 5.65 ENST00000423485.1
topoisomerase (DNA) II alpha 170kDa
chr12_-_56122220 5.64 ENST00000552692.1
CD63 molecule
chr2_-_151344172 5.56 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
Rho family GTPase 3
chr17_+_66509019 5.55 ENST00000585981.1
ENST00000589480.1
ENST00000585815.1
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr9_-_127624194 5.50 ENST00000373570.4
ENST00000348462.3
ribosomal protein L35
chr1_+_145301735 5.50 ENST00000605176.1
neuroblastoma breakpoint family, member 10
chr19_-_14945933 5.48 ENST00000322301.3
olfactory receptor, family 7, subfamily A, member 5
chr1_+_158900568 5.48 ENST00000458222.1
pyrin and HIN domain family, member 1
chr17_+_7155819 5.48 ENST00000570322.1
ENST00000576496.1
ENST00000574841.2
elongator acetyltransferase complex subunit 5
chr2_+_89952792 5.46 ENST00000390265.2
immunoglobulin kappa variable 1D-33
chr7_+_116502605 5.45 ENST00000458284.2
ENST00000490693.1
capping protein (actin filament) muscle Z-line, alpha 2
chr18_+_3252206 5.45 ENST00000578562.2
myosin, light chain 12A, regulatory, non-sarcomeric
chr2_+_201994042 5.41 ENST00000417748.1
CASP8 and FADD-like apoptosis regulator
chr2_+_90060377 5.41 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr7_-_7679633 5.40 ENST00000401447.1
replication protein A3, 14kDa
chr6_+_7541845 5.39 ENST00000418664.2
desmoplakin
chr10_-_5046042 5.38 ENST00000421196.3
ENST00000455190.1
aldo-keto reductase family 1, member C2
chr4_+_69962185 5.35 ENST00000305231.7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr14_+_52456193 5.34 ENST00000261700.3
chromosome 14 open reading frame 166
chr11_-_47664072 5.32 ENST00000542981.1
ENST00000530428.1
ENST00000302503.3
mitochondrial carrier 2
chr10_-_95241951 5.31 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
myoferlin
chr15_+_65843130 5.28 ENST00000569894.1
protein tyrosine phosphatase-like A domain containing 1
chr12_+_75874460 5.24 ENST00000266659.3
GLI pathogenesis-related 1
chr12_+_48357401 5.24 ENST00000429772.2
ENST00000449758.2
transmembrane protein 106C
chr1_-_211848899 5.24 ENST00000366998.3
ENST00000540251.1
ENST00000366999.4
NIMA-related kinase 2
chr14_+_56127989 5.23 ENST00000555573.1
kinectin 1 (kinesin receptor)
chr7_+_107224364 5.23 ENST00000491150.1
B-cell receptor-associated protein 29
chr6_-_8102279 5.21 ENST00000488226.2
eukaryotic translation elongation factor 1 epsilon 1
chr1_-_153518270 5.21 ENST00000354332.4
ENST00000368716.4
S100 calcium binding protein A4
chr11_+_35201826 5.20 ENST00000531873.1
CD44 molecule (Indian blood group)
chr2_+_219110149 5.17 ENST00000456575.1
actin related protein 2/3 complex, subunit 2, 34kDa
chr19_+_30414551 5.17 ENST00000360605.4
ENST00000570564.1
ENST00000574233.1
ENST00000585655.1
URI1, prefoldin-like chaperone
chr16_+_33605231 5.16 ENST00000570121.2
immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr2_-_169769787 5.15 ENST00000451987.1
SPC25, NDC80 kinetochore complex component
chr1_-_146082633 5.15 ENST00000605317.1
ENST00000604938.1
ENST00000339388.5
neuroblastoma breakpoint family, member 11
chr11_-_10828892 5.13 ENST00000525681.1
eukaryotic translation initiation factor 4 gamma, 2
chr16_+_33006369 5.13 ENST00000425181.3
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr14_-_106552755 5.12 ENST00000390600.2
immunoglobulin heavy variable 3-9
chr5_-_10761206 5.11 ENST00000432074.2
ENST00000230895.6
death-associated protein
chr12_+_113344755 5.07 ENST00000550883.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr7_+_116502527 5.07 ENST00000361183.3
capping protein (actin filament) muscle Z-line, alpha 2
chr8_+_30244580 5.06 ENST00000523115.1
ENST00000519647.1
RNA binding protein with multiple splicing
chr10_-_94257512 5.05 ENST00000371581.5
insulin-degrading enzyme
chr9_-_95056010 5.04 ENST00000443024.2
isoleucyl-tRNA synthetase
chr14_-_106539557 5.02 ENST00000390599.2
immunoglobulin heavy variable 1-8
chr2_+_120125245 5.01 ENST00000393103.2
diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr2_-_89340242 5.00 ENST00000480492.1
immunoglobulin kappa variable 1-12
chr8_+_55047763 4.99 ENST00000260102.4
ENST00000519831.1
mitochondrial ribosomal protein L15
chr1_-_63988846 4.98 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
integrin beta 3 binding protein (beta3-endonexin)
chr2_-_89630186 4.98 ENST00000390264.2
immunoglobulin kappa variable 2-40
chr7_+_117824210 4.97 ENST00000422760.1
ENST00000411938.1
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr5_-_96518907 4.96 ENST00000508447.1
ENST00000283109.3
RIO kinase 2
chr4_+_83956312 4.95 ENST00000509317.1
ENST00000503682.1
ENST00000511653.1
COP9 signalosome subunit 4
chr2_+_73461410 4.94 ENST00000399032.2
ENST00000398422.2
ENST00000537131.1
ENST00000538797.1
chaperonin containing TCP1, subunit 7 (eta)
chr2_+_73461364 4.94 ENST00000540468.1
ENST00000539919.1
ENST00000258091.5
chaperonin containing TCP1, subunit 7 (eta)
chr2_+_89901292 4.92 ENST00000448155.2
immunoglobulin kappa variable 1D-39
chr1_-_145827015 4.89 ENST00000534502.1
ENST00000313835.9
ENST00000454423.3
G protein-coupled receptor 89A
chr14_-_58893832 4.87 ENST00000556007.2
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr15_-_22473353 4.87 ENST00000557788.2
immunoglobulin heavy variable 4/OR15-8 (non-functional)
chr7_+_107531580 4.86 ENST00000537148.1
ENST00000440410.1
ENST00000437604.2
dihydrolipoamide dehydrogenase

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC8

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.3 18.8 GO:0002188 translation reinitiation(GO:0002188)
5.0 19.9 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
4.8 4.8 GO:0009205 purine nucleoside triphosphate metabolic process(GO:0009144) purine ribonucleoside triphosphate metabolic process(GO:0009205)
3.6 21.5 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
3.5 24.6 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
3.4 10.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
2.9 8.7 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
2.9 5.8 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
2.8 11.2 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
2.7 2.7 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791) medium-chain fatty acid biosynthetic process(GO:0051792)
2.7 11.0 GO:0071461 cellular response to redox state(GO:0071461)
2.7 21.4 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
2.6 12.8 GO:0042100 B cell proliferation(GO:0042100)
2.5 7.5 GO:0090149 mitochondrial membrane fission(GO:0090149)
2.4 9.7 GO:0060623 regulation of chromosome condensation(GO:0060623)
2.4 23.5 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
2.3 6.9 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
2.2 6.7 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
2.1 6.4 GO:0006738 nicotinamide riboside catabolic process(GO:0006738) inosine metabolic process(GO:0046102) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
1.9 1.9 GO:0035690 cellular response to drug(GO:0035690)
1.9 13.4 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
1.8 11.0 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
1.8 7.2 GO:0046452 dihydrofolate metabolic process(GO:0046452)
1.7 8.5 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
1.7 5.1 GO:0046098 guanine metabolic process(GO:0046098)
1.7 5.1 GO:1901143 insulin catabolic process(GO:1901143)
1.7 5.0 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
1.7 6.7 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
1.7 21.5 GO:0000492 box C/D snoRNP assembly(GO:0000492)
1.7 8.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
1.6 4.8 GO:1900195 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
1.6 6.3 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
1.6 233.2 GO:0006958 complement activation, classical pathway(GO:0006958)
1.5 4.6 GO:0090244 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of cell fate specification(GO:0009996) Wnt signaling pathway involved in somitogenesis(GO:0090244)
1.5 4.5 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
1.5 13.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
1.5 5.8 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
1.4 4.3 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
1.4 7.2 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
1.4 12.9 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
1.4 7.2 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
1.4 8.4 GO:0055064 chloride ion homeostasis(GO:0055064)
1.4 5.5 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
1.3 6.7 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
1.3 9.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
1.3 7.7 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
1.3 12.6 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
1.2 9.9 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
1.2 6.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
1.2 4.9 GO:0009106 lipoate metabolic process(GO:0009106)
1.2 4.8 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
1.2 9.5 GO:0001887 selenium compound metabolic process(GO:0001887)
1.2 7.0 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
1.2 9.3 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
1.1 1.1 GO:0051673 pore formation in membrane of other organism(GO:0035915) membrane disruption in other organism(GO:0051673)
1.1 5.5 GO:0070980 biphenyl catabolic process(GO:0070980)
1.1 3.2 GO:0070632 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
1.1 11.8 GO:0006621 protein retention in ER lumen(GO:0006621)
1.1 3.2 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
1.0 15.5 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
1.0 13.3 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
1.0 3.0 GO:0097205 glomerular filtration(GO:0003094) renal filtration(GO:0097205)
1.0 3.9 GO:0015965 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
1.0 8.8 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
1.0 6.8 GO:0090204 protein localization to nuclear pore(GO:0090204)
1.0 5.8 GO:0042866 pyruvate biosynthetic process(GO:0042866)
1.0 3.8 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.9 2.8 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.9 4.7 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.9 3.7 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.9 5.5 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.9 3.6 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.9 3.5 GO:0019046 release from viral latency(GO:0019046)
0.8 5.0 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.8 4.2 GO:0060337 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.8 10.0 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.8 12.5 GO:0090168 Golgi reassembly(GO:0090168)
0.8 2.5 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.8 2.4 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.8 8.8 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.8 3.2 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.8 3.2 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.8 19.1 GO:0008053 mitochondrial fusion(GO:0008053)
0.8 1.6 GO:0001302 replicative cell aging(GO:0001302)
0.8 4.7 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.8 3.9 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.8 2.3 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.8 9.9 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.8 37.1 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.8 9.8 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.8 2.3 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
0.8 36.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.7 3.7 GO:0006574 valine catabolic process(GO:0006574)
0.7 6.0 GO:0060242 contact inhibition(GO:0060242)
0.7 3.0 GO:0000103 sulfate assimilation(GO:0000103)
0.7 17.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.7 3.7 GO:1902775 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.7 11.6 GO:0000338 protein deneddylation(GO:0000338)
0.7 4.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.7 8.6 GO:0001778 plasma membrane repair(GO:0001778)
0.7 4.3 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.7 4.1 GO:0032790 ribosome disassembly(GO:0032790)
0.7 12.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.7 4.1 GO:0030952 establishment or maintenance of actin cytoskeleton polarity(GO:0030950) establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.7 4.7 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.7 4.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.7 10.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.6 2.6 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.6 11.8 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.6 1.9 GO:0043605 cellular amide catabolic process(GO:0043605)
0.6 6.1 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.6 2.4 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.6 5.4 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223) cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.6 11.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.6 3.0 GO:1903243 negative regulation of cardiac muscle adaptation(GO:0010616) transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) negative regulation of lung blood pressure(GO:0061767) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.6 1.2 GO:0002215 defense response to nematode(GO:0002215)
0.6 3.5 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.6 5.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.6 1.7 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.6 9.8 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.6 2.9 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.6 32.3 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
0.6 5.6 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.6 3.4 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.6 2.8 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.5 3.8 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.5 14.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.5 13.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.5 1.6 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.5 2.6 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.5 1.0 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.5 3.1 GO:0035803 egg coat formation(GO:0035803)
0.5 56.6 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.5 4.1 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.5 5.4 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.5 2.5 GO:0007063 regulation of sister chromatid cohesion(GO:0007063)
0.5 2.9 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.5 1.0 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.5 8.3 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.5 2.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.5 2.9 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.5 6.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.5 13.2 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.5 77.6 GO:0002377 immunoglobulin production(GO:0002377)
0.5 1.9 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.5 9.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.4 4.5 GO:0006739 NADP metabolic process(GO:0006739)
0.4 4.5 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.4 1.3 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.4 1.8 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.4 5.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.4 1.3 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.4 1.7 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.4 4.2 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.4 1.7 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.4 5.4 GO:0070987 error-free translesion synthesis(GO:0070987)
0.4 8.6 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.4 2.4 GO:0071233 cellular response to leucine(GO:0071233)
0.4 0.8 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.4 7.3 GO:0002227 innate immune response in mucosa(GO:0002227)
0.4 6.8 GO:0072697 protein localization to cell cortex(GO:0072697)
0.4 3.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.4 4.8 GO:0051775 response to redox state(GO:0051775)
0.4 2.8 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.4 4.7 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.4 3.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.4 6.2 GO:0051639 actin filament network formation(GO:0051639)
0.4 8.2 GO:0003334 keratinocyte development(GO:0003334)
0.4 11.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.4 0.4 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.4 1.1 GO:0070858 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) negative regulation of bile acid biosynthetic process(GO:0070858) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) negative regulation of bile acid metabolic process(GO:1904252) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.4 2.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.4 6.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.4 3.0 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.4 6.6 GO:0052695 cellular glucuronidation(GO:0052695)
0.4 2.9 GO:0072718 response to cisplatin(GO:0072718)
0.4 1.8 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.4 1.4 GO:0030047 actin modification(GO:0030047)
0.4 2.5 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.4 47.9 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.4 1.1 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
0.4 1.8 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.4 2.8 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.3 1.7 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.3 2.0 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856) response to oleic acid(GO:0034201)
0.3 3.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.3 3.4 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.3 2.7 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.3 1.0 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.3 9.6 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.3 2.6 GO:0042262 DNA protection(GO:0042262)
0.3 3.6 GO:0051451 myoblast migration(GO:0051451)
0.3 2.6 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.3 6.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.3 14.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.3 0.6 GO:0035587 purinergic receptor signaling pathway(GO:0035587) purinergic nucleotide receptor signaling pathway(GO:0035590)
0.3 6.0 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.3 1.8 GO:0009249 protein lipoylation(GO:0009249)
0.3 21.4 GO:0034644 cellular response to UV(GO:0034644)
0.3 1.1 GO:0010976 positive regulation of neuron projection development(GO:0010976)
0.3 1.1 GO:1904640 response to methionine(GO:1904640)
0.3 10.5 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.3 1.4 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.3 2.7 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.3 1.3 GO:0090131 mesenchyme migration(GO:0090131)
0.3 0.8 GO:0061316 regulation of Wnt signaling pathway involved in heart development(GO:0003307) arterial endothelial cell fate commitment(GO:0060844) canonical Wnt signaling pathway involved in heart development(GO:0061316) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.3 7.4 GO:0014904 myotube cell development(GO:0014904)
0.3 6.9 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.3 1.8 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.3 3.4 GO:0006089 lactate metabolic process(GO:0006089)
0.3 4.1 GO:0016180 snRNA processing(GO:0016180)
0.3 0.8 GO:0045575 basophil activation(GO:0045575)
0.2 2.7 GO:0006295 nucleotide-excision repair, preincision complex stabilization(GO:0006293) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.2 1.5 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.2 2.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.2 4.6 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.2 3.9 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.2 1.7 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.2 1.4 GO:0009441 glycolate metabolic process(GO:0009441)
0.2 2.9 GO:0070986 left/right axis specification(GO:0070986)
0.2 3.8 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.2 0.9 GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332) negative regulation of cholesterol efflux(GO:0090370)
0.2 1.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.2 1.8 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.2 2.2 GO:1902969 mitotic DNA replication(GO:1902969)
0.2 1.3 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.2 0.6 GO:0043137 DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.2 6.2 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.2 1.9 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 1.0 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.2 1.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.2 5.0 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.2 1.6 GO:0015693 magnesium ion transport(GO:0015693)
0.2 3.3 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.2 7.4 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.2 12.8 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.2 0.4 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.2 4.7 GO:0035455 response to interferon-alpha(GO:0035455)
0.2 5.0 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.2 0.7 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.2 1.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.2 1.5 GO:0006013 mannose metabolic process(GO:0006013)
0.2 0.5 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.2 0.9 GO:0051944 peptidyl-cysteine methylation(GO:0018125) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.2 0.9 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.2 1.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 1.0 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2 2.0 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 2.9 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.2 0.5 GO:0051685 maintenance of ER location(GO:0051685)
0.2 2.7 GO:0060850 regulation of transcription involved in cell fate commitment(GO:0060850)
0.2 3.4 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.2 5.7 GO:0060216 definitive hemopoiesis(GO:0060216)
0.2 1.3 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.2 8.3 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.2 1.5 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.2 0.6 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.2 1.8 GO:0043249 erythrocyte maturation(GO:0043249)
0.2 0.8 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.2 3.0 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 1.6 GO:0051764 actin crosslink formation(GO:0051764)
0.2 6.8 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.2 0.5 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.2 1.5 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.1 8.2 GO:0051452 intracellular pH reduction(GO:0051452)
0.1 0.6 GO:1904796 regulation of core promoter binding(GO:1904796)
0.1 0.7 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 1.0 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 1.6 GO:0060009 Sertoli cell development(GO:0060009)
0.1 3.2 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 9.5 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.1 1.3 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.1 1.1 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.1 1.9 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 0.7 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.1 1.0 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 0.7 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065) glucose 1-phosphate metabolic process(GO:0019255)
0.1 1.1 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 1.6 GO:0010658 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659)
0.1 8.1 GO:0031100 organ regeneration(GO:0031100)
0.1 1.4 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 2.8 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 0.7 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 7.6 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 0.9 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.1 2.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 3.5 GO:0050667 homocysteine metabolic process(GO:0050667)
0.1 1.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.8 GO:0043497 regulation of protein heterodimerization activity(GO:0043497) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 5.4 GO:0050850 positive regulation of calcium-mediated signaling(GO:0050850)
0.1 1.1 GO:1900376 regulation of melanin biosynthetic process(GO:0048021) positive regulation of melanin biosynthetic process(GO:0048023) regulation of secondary metabolite biosynthetic process(GO:1900376) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1 2.8 GO:0006414 translational elongation(GO:0006414)
0.1 5.2 GO:0043484 regulation of RNA splicing(GO:0043484)
0.1 0.6 GO:0008218 bioluminescence(GO:0008218)
0.1 0.9 GO:0006772 thiamine metabolic process(GO:0006772)
0.1 0.7 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 1.1 GO:0030183 B cell differentiation(GO:0030183)
0.1 1.1 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 2.4 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 1.7 GO:0097264 self proteolysis(GO:0097264)
0.1 3.3 GO:0014823 response to activity(GO:0014823)
0.1 1.3 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.7 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 2.8 GO:0048846 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.1 6.5 GO:0006342 chromatin silencing(GO:0006342)
0.1 2.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 2.8 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1 1.8 GO:0016540 protein autoprocessing(GO:0016540)
0.1 2.5 GO:0031639 plasminogen activation(GO:0031639)
0.1 0.2 GO:0035630 bone mineralization involved in bone maturation(GO:0035630) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1 4.0 GO:0046710 GDP metabolic process(GO:0046710)
0.1 0.9 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.1 11.7 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.6 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.1 0.5 GO:0043585 nose morphogenesis(GO:0043585) alveolar primary septum development(GO:0061143)
0.1 0.3 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.9 GO:0031053 primary miRNA processing(GO:0031053)
0.1 0.2 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.5 GO:0038203 TORC2 signaling(GO:0038203)
0.1 2.3 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.6 GO:0030578 PML body organization(GO:0030578)
0.1 0.3 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.3 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 8.2 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 1.0 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.9 GO:0002158 osteoclast proliferation(GO:0002158) pancreatic juice secretion(GO:0030157)
0.1 0.8 GO:0051546 keratinocyte migration(GO:0051546)
0.1 4.2 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 0.7 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition(GO:0051437)
0.1 0.8 GO:0070828 heterochromatin organization(GO:0070828)
0.1 1.1 GO:0010629 negative regulation of gene expression(GO:0010629)
0.1 0.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.9 GO:0017004 cytochrome complex assembly(GO:0017004)
0.1 1.9 GO:0030728 ovulation(GO:0030728)
0.1 0.2 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1 2.0 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 7.4 GO:0045727 positive regulation of translation(GO:0045727)
0.1 1.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 1.2 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 0.9 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.1 4.2 GO:0006446 regulation of translational initiation(GO:0006446)
0.1 0.8 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 1.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 1.9 GO:1901998 toxin transport(GO:1901998)
0.1 1.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 1.7 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.1 1.1 GO:0072643 interferon-gamma secretion(GO:0072643)
0.1 1.4 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 0.7 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.4 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.5 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.1 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 2.7 GO:0045815 positive regulation of gene expression, epigenetic(GO:0045815)
0.1 1.6 GO:0002076 osteoblast development(GO:0002076)
0.1 1.8 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.1 0.8 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.1 1.3 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 0.3 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 0.3 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 0.2 GO:0048696 regulation of collateral sprouting in absence of injury(GO:0048696) negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 1.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 1.8 GO:0050832 defense response to fungus(GO:0050832)
0.1 1.8 GO:0042246 tissue regeneration(GO:0042246)
0.1 0.2 GO:1902744 negative regulation of lamellipodium organization(GO:1902744) negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 4.2 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.1 4.9 GO:0019827 stem cell population maintenance(GO:0019827) maintenance of cell number(GO:0098727)
0.1 1.8 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.1 0.1 GO:1902994 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.1 0.2 GO:0002027 regulation of heart rate(GO:0002027)
0.1 4.2 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 1.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 3.2 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.2 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 2.9 GO:1903311 regulation of mRNA metabolic process(GO:1903311)
0.0 1.9 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.5 GO:0045008 depyrimidination(GO:0045008)
0.0 0.7 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 1.1 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.9 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 3.6 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.8 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.9 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.4 GO:0042180 cellular ketone metabolic process(GO:0042180)
0.0 0.2 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0 0.9 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 1.6 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.5 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.4 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 2.1 GO:0006401 RNA catabolic process(GO:0006401)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:0043586 tongue development(GO:0043586)
0.0 2.5 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 2.1 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 0.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240) detection of muscle stretch(GO:0035995)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.4 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 1.1 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.0 0.2 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 0.3 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.9 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.8 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.4 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.6 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0098502 DNA dephosphorylation(GO:0098502)
0.0 0.9 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.0 1.1 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.3 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.5 GO:0048477 oogenesis(GO:0048477)
0.0 0.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 1.4 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.1 GO:1902603 carnitine transmembrane transport(GO:1902603)
0.0 0.1 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.8 GO:0008360 regulation of cell shape(GO:0008360)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 22.8 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
3.8 11.3 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
3.6 14.3 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
3.1 21.4 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
2.8 22.6 GO:0005672 transcription factor TFIIA complex(GO:0005672)
2.7 19.1 GO:0061617 MICOS complex(GO:0061617)
2.6 20.9 GO:0005683 U7 snRNP(GO:0005683)
2.4 9.6 GO:0031417 NatC complex(GO:0031417)
2.2 11.0 GO:0043564 Ku70:Ku80 complex(GO:0043564)
1.9 97.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
1.9 15.4 GO:0070761 pre-snoRNP complex(GO:0070761)
1.9 13.4 GO:0044326 dendritic spine neck(GO:0044326)
1.9 5.6 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
1.8 5.5 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
1.7 5.2 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
1.7 5.1 GO:0031262 Ndc80 complex(GO:0031262)
1.7 6.7 GO:1990423 RZZ complex(GO:1990423)
1.6 4.9 GO:0043159 acrosomal matrix(GO:0043159)
1.6 4.8 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
1.6 4.8 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
1.6 9.4 GO:0001740 Barr body(GO:0001740)
1.5 6.2 GO:0001940 male pronucleus(GO:0001940)
1.5 9.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
1.5 6.1 GO:0033186 CAF-1 complex(GO:0033186)
1.5 11.7 GO:0032133 chromosome passenger complex(GO:0032133)
1.4 10.0 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
1.4 11.2 GO:0005610 laminin-5 complex(GO:0005610)
1.3 6.5 GO:0071148 TEAD-1-YAP complex(GO:0071148)
1.3 40.5 GO:0005838 proteasome regulatory particle(GO:0005838)
1.2 3.7 GO:0034455 t-UTP complex(GO:0034455)
1.2 6.2 GO:0071986 Ragulator complex(GO:0071986)
1.2 2.5 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
1.2 5.8 GO:0097149 centralspindlin complex(GO:0097149)
1.1 6.7 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
1.1 12.1 GO:0000243 commitment complex(GO:0000243)
1.1 5.4 GO:0034457 Mpp10 complex(GO:0034457)
1.1 3.2 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
1.1 16.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
1.0 9.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
1.0 11.8 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
1.0 2.9 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
1.0 20.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
1.0 3.9 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.9 6.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.8 5.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.8 15.1 GO:0097342 ripoptosome(GO:0097342)
0.8 6.7 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.8 2.5 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.8 4.0 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.8 13.2 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.8 5.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.8 2.3 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.8 3.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.8 9.9 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.8 12.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.7 2.9 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.7 54.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.7 7.9 GO:0070765 gamma-secretase complex(GO:0070765)
0.7 4.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.7 10.5 GO:0008290 F-actin capping protein complex(GO:0008290)
0.7 4.1 GO:0005688 U6 snRNP(GO:0005688)
0.7 4.0 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.6 3.8 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.6 7.0 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.6 3.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.6 13.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.6 6.0 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.6 6.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.6 2.4 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.6 5.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.6 4.6 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.6 5.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.6 2.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.6 8.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.5 3.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.5 4.3 GO:0042382 paraspeckles(GO:0042382)
0.5 16.5 GO:0035371 microtubule plus-end(GO:0035371)
0.5 4.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.5 6.5 GO:0005681 spliceosomal complex(GO:0005681)
0.5 9.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.5 3.9 GO:1990111 spermatoproteasome complex(GO:1990111)
0.5 13.1 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.5 1.9 GO:0097224 sperm connecting piece(GO:0097224)
0.5 2.8 GO:0016272 prefoldin complex(GO:0016272)
0.5 9.4 GO:0005839 proteasome core complex(GO:0005839)
0.5 8.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.5 3.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.5 4.1 GO:0032039 integrator complex(GO:0032039)
0.5 7.8 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.4 4.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.4 15.6 GO:0005844 polysome(GO:0005844)
0.4 1.7 GO:0030891 VCB complex(GO:0030891)
0.4 10.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.4 5.8 GO:0010369 chromocenter(GO:0010369)
0.4 4.9 GO:0043219 lateral loop(GO:0043219)
0.4 22.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.4 11.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.4 4.3 GO:0071011 precatalytic spliceosome(GO:0071011)
0.4 5.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.4 12.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.4 3.0 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.4 1.5 GO:0005797 Golgi medial cisterna(GO:0005797)
0.4 1.8 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.3 3.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.3 17.0 GO:0008180 COP9 signalosome(GO:0008180)
0.3 48.8 GO:0015934 large ribosomal subunit(GO:0015934)
0.3 4.6 GO:0038201 TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.3 3.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.3 1.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.3 16.6 GO:0000786 nucleosome(GO:0000786)
0.3 4.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.3 5.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.3 3.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.3 2.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.3 0.9 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.3 6.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.3 3.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.3 6.1 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.3 4.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.3 1.9 GO:0030870 Mre11 complex(GO:0030870)
0.3 3.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3 4.2 GO:0032040 small-subunit processome(GO:0032040)
0.3 2.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.3 5.6 GO:0031105 septin complex(GO:0031105)
0.3 2.8 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.3 2.8 GO:0000124 SAGA complex(GO:0000124)
0.3 13.9 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3 17.5 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.2 3.4 GO:0031209 SCAR complex(GO:0031209)
0.2 1.6 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.2 1.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.2 2.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.2 20.9 GO:0016459 myosin complex(GO:0016459)
0.2 5.9 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.2 13.8 GO:0035577 azurophil granule membrane(GO:0035577)
0.2 2.2 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.2 1.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.2 5.4 GO:0030057 desmosome(GO:0030057)
0.2 6.7 GO:0031430 M band(GO:0031430)
0.2 10.9 GO:0002102 podosome(GO:0002102)
0.2 1.3 GO:0005869 dynactin complex(GO:0005869)
0.2 4.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 7.0 GO:0000421 autophagosome membrane(GO:0000421)
0.2 11.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 3.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 1.8 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 33.4 GO:0072562 blood microparticle(GO:0072562)
0.2 0.4 GO:0033011 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.2 3.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.2 1.9 GO:0005915 zonula adherens(GO:0005915)
0.2 1.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.2 5.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 7.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.2 25.9 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.2 0.7 GO:0002177 manchette(GO:0002177)
0.2 5.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.2 0.7 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.2 2.4 GO:0000785 chromatin(GO:0000785)
0.2 0.8 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 0.9 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.1 1.8 GO:0000815 ESCRT III complex(GO:0000815)
0.1 2.0 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 8.0 GO:0015030 Cajal body(GO:0015030)
0.1 1.5 GO:0042555 MCM complex(GO:0042555)
0.1 6.8 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.5 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 1.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.7 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 2.5 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1 0.9 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 2.5 GO:0043034 costamere(GO:0043034)
0.1 11.4 GO:0005901 caveola(GO:0005901)
0.1 8.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 3.9 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 5.7 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 3.0 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.4 GO:0001772 immunological synapse(GO:0001772)
0.1 2.4 GO:0097542 ciliary tip(GO:0097542)
0.1 3.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 2.9 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 3.7 GO:0016235 aggresome(GO:0016235)
0.1 8.7 GO:0005604 basement membrane(GO:0005604)
0.1 3.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 5.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 4.9 GO:0032432 actin filament bundle(GO:0032432)
0.1 2.7 GO:0016592 mediator complex(GO:0016592)
0.1 1.8 GO:0031941 filamentous actin(GO:0031941)
0.1 7.4 GO:0000922 spindle pole(GO:0000922)
0.1 0.1 GO:0055087 Ski complex(GO:0055087)
0.1 2.9 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 0.9 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.9 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.4 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.6 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 1.0 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 20.7 GO:0016607 nuclear speck(GO:0016607)
0.1 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 4.7 GO:0000781 chromosome, telomeric region(GO:0000781)
0.1 3.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.4 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 5.7 GO:0001650 fibrillar center(GO:0001650)
0.1 0.5 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 3.3 GO:0005882 intermediate filament(GO:0005882)
0.0 1.5 GO:0005840 ribosome(GO:0005840)
0.0 1.1 GO:0090544 BAF-type complex(GO:0090544)
0.0 5.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 48.6 GO:0005615 extracellular space(GO:0005615)
0.0 6.3 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.9 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 1.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 3.9 GO:0005819 spindle(GO:0005819)
0.0 13.6 GO:0005730 nucleolus(GO:0005730)
0.0 1.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 1.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.4 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.4 GO:0031201 SNARE complex(GO:0031201)
0.0 0.3 GO:0005776 autophagosome(GO:0005776)
0.0 0.3 GO:0097381 photoreceptor disc membrane(GO:0097381)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 19.2 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
3.6 10.9 GO:0050613 delta14-sterol reductase activity(GO:0050613)
3.4 10.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
3.1 9.3 GO:0042134 rRNA primary transcript binding(GO:0042134)
3.0 11.8 GO:0005046 KDEL sequence binding(GO:0005046)
2.8 8.3 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
2.4 7.2 GO:0070538 oleic acid binding(GO:0070538)
2.4 7.1 GO:0098625 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
2.3 23.4 GO:0019237 centromeric DNA binding(GO:0019237)
2.3 6.8 GO:0017130 poly(C) RNA binding(GO:0017130)
2.1 6.4 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
2.0 6.0 GO:0001069 regulatory region RNA binding(GO:0001069)
1.9 5.6 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
1.8 5.4 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
1.8 97.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
1.8 5.3 GO:0000035 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
1.7 12.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
1.7 10.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
1.7 5.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
1.7 5.0 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
1.6 6.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.5 10.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
1.4 5.8 GO:0004743 pyruvate kinase activity(GO:0004743)
1.3 11.7 GO:0035174 histone serine kinase activity(GO:0035174)
1.3 7.7 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
1.3 17.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
1.3 5.0 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
1.2 12.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
1.2 3.5 GO:0070260 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
1.2 4.7 GO:0016936 galactoside binding(GO:0016936)
1.2 12.9 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
1.2 11.6 GO:0019784 NEDD8-specific protease activity(GO:0019784)
1.1 6.8 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
1.1 4.5 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
1.1 208.4 GO:0003823 antigen binding(GO:0003823)
1.1 25.8 GO:0008143 poly(A) binding(GO:0008143)
1.1 11.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
1.1 15.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
1.1 4.4 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
1.1 4.3 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
1.1 22.8 GO:0035173 histone kinase activity(GO:0035173)
1.1 4.3 GO:0043515 kinetochore binding(GO:0043515)
1.0 11.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
1.0 4.1 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
1.0 3.0 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
1.0 6.7 GO:0004849 uridine kinase activity(GO:0004849)
0.9 8.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.9 4.5 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.9 3.6 GO:1990446 U1 snRNP binding(GO:1990446)
0.9 6.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.9 2.6 GO:0035529 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) NADH pyrophosphatase activity(GO:0035529) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.8 22.6 GO:0017025 TBP-class protein binding(GO:0017025)
0.8 2.5 GO:0034046 poly(G) binding(GO:0034046)
0.8 2.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.8 2.5 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.8 2.5 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.8 8.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.8 3.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.8 4.7 GO:0019238 cyclohydrolase activity(GO:0019238)
0.8 4.6 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.8 3.8 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.8 23.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.8 6.1 GO:0004111 creatine kinase activity(GO:0004111)
0.7 22.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.7 2.9 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.7 2.2 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.7 4.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.7 2.9 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.7 2.8 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.7 7.7 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.7 2.0 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.7 6.8 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.7 3.3 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.6 3.9 GO:0003796 lysozyme activity(GO:0003796)
0.6 2.6 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.6 3.9 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.6 3.2 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.6 10.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.6 5.1 GO:0043559 insulin binding(GO:0043559)
0.6 6.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.6 3.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.6 4.9 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.6 6.0 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.6 5.4 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.6 2.4 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.6 3.0 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.6 4.7 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.6 5.8 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.6 2.3 GO:0035877 death effector domain binding(GO:0035877)
0.6 6.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.6 2.3 GO:0061134 peptidase regulator activity(GO:0061134)
0.6 2.2 GO:0048763 HLH domain binding(GO:0043398) calcium-induced calcium release activity(GO:0048763)
0.6 2.8 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.5 11.7 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.5 2.6 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.5 3.7 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.5 3.7 GO:0030621 U4 snRNA binding(GO:0030621)
0.5 4.6 GO:0039706 co-receptor binding(GO:0039706)
0.5 5.0 GO:0042731 PH domain binding(GO:0042731)
0.5 5.4 GO:0015266 protein channel activity(GO:0015266)
0.5 9.8 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.5 3.4 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.5 1.4 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.5 7.6 GO:0031369 translation initiation factor binding(GO:0031369)
0.5 4.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.5 21.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.5 8.7 GO:0097602 cullin family protein binding(GO:0097602)
0.5 33.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.4 2.2 GO:0034056 estrogen response element binding(GO:0034056)
0.4 1.8 GO:0030305 beta-glucuronidase activity(GO:0004566) heparanase activity(GO:0030305)
0.4 9.2 GO:0030515 snoRNA binding(GO:0030515)
0.4 1.3 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.4 2.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.4 2.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.4 1.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.4 3.9 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.4 1.2 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.4 10.1 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.4 2.7 GO:0008142 oxysterol binding(GO:0008142)
0.4 1.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.4 1.1 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.4 14.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.4 1.1 GO:0004461 lactose synthase activity(GO:0004461)
0.4 9.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.4 9.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.3 11.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.3 4.8 GO:0016018 cyclosporin A binding(GO:0016018)
0.3 1.0 GO:0033149 FFAT motif binding(GO:0033149)
0.3 2.6 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.3 1.3 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.3 5.9 GO:0016289 CoA hydrolase activity(GO:0016289)
0.3 3.2 GO:0019826 oxygen sensor activity(GO:0019826)
0.3 7.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.3 2.9 GO:0032190 acrosin binding(GO:0032190)
0.3 67.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 0.9 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.3 2.8 GO:0017070 U6 snRNA binding(GO:0017070)
0.3 7.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 4.9 GO:0017049 GTP-Rho binding(GO:0017049)
0.3 4.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.3 5.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.3 6.1 GO:0070628 proteasome binding(GO:0070628)
0.3 5.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.3 2.9 GO:0050543 icosanoid binding(GO:0050542) icosatetraenoic acid binding(GO:0050543) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.3 0.9 GO:0004802 transketolase activity(GO:0004802)
0.3 4.0 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.3 3.1 GO:0031419 cobalamin binding(GO:0031419)
0.3 2.7 GO:0004312 fatty acid synthase activity(GO:0004312)
0.3 1.9 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3 0.8 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.3 2.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.3 3.2 GO:0032027 myosin light chain binding(GO:0032027)
0.3 1.9 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.3 0.8 GO:0000150 recombinase activity(GO:0000150)
0.3 1.1 GO:0061714 methotrexate binding(GO:0051870) folic acid receptor activity(GO:0061714)
0.3 2.9 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.3 23.6 GO:0032947 protein complex scaffold(GO:0032947)
0.3 6.0 GO:0070064 proline-rich region binding(GO:0070064)
0.3 12.2 GO:0042169 SH2 domain binding(GO:0042169)
0.3 28.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.3 0.8 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.2 1.7 GO:0089720 caspase binding(GO:0089720)
0.2 0.7 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.2 2.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 3.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 3.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.2 5.2 GO:0070300 phosphatidic acid binding(GO:0070300)
0.2 0.7 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.2 4.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 3.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 3.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 3.0 GO:0001671 ATPase activator activity(GO:0001671)
0.2 6.8 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 2.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2 7.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 1.3 GO:0019776 Atg8 ligase activity(GO:0019776)
0.2 3.4 GO:0005537 mannose binding(GO:0005537)
0.2 5.5 GO:0071949 FAD binding(GO:0071949)
0.2 2.3 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 1.0 GO:0070728 leucine binding(GO:0070728)
0.2 16.8 GO:0005518 collagen binding(GO:0005518)
0.2 13.2 GO:0035064 methylated histone binding(GO:0035064)
0.2 1.8 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.2 9.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.2 19.2 GO:0051087 chaperone binding(GO:0051087)
0.2 1.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 3.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 0.4 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.2 1.8 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.2 2.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2 0.9 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.2 8.6 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 5.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 5.5 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.2 0.7 GO:0004948 calcitonin receptor activity(GO:0004948)
0.2 1.4 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.2 2.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.2 0.5 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 0.7 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.2 1.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 1.6 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.2 3.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 2.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 1.6 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2 1.1 GO:0070573 metallodipeptidase activity(GO:0070573)
0.1 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.9 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 3.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 2.8 GO:0004697 protein kinase C activity(GO:0004697)
0.1 2.6 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.1 4.1 GO:0005080 protein kinase C binding(GO:0005080)
0.1 4.4 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 0.5 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 5.9 GO:0050681 androgen receptor binding(GO:0050681)
0.1 0.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.9 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 0.8 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 17.1 GO:0017124 SH3 domain binding(GO:0017124)
0.1 1.8 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 1.0 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 0.7 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 3.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 2.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 1.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 2.5 GO:0019843 rRNA binding(GO:0019843)
0.1 3.7 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 1.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 2.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.6 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 2.4 GO:0031489 myosin V binding(GO:0031489)
0.1 2.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 10.8 GO:0005178 integrin binding(GO:0005178)
0.1 0.2 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.1 3.8 GO:0097110 scaffold protein binding(GO:0097110)
0.1 1.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.5 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.1 1.1 GO:0032183 SUMO binding(GO:0032183)
0.1 24.8 GO:0045296 cadherin binding(GO:0045296)
0.1 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 2.9 GO:0061650 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.1 1.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 3.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 2.4 GO:0050699 WW domain binding(GO:0050699)
0.1 0.3 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 3.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.2 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 0.8 GO:0031491 nucleosome binding(GO:0031491)
0.1 3.1 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 4.5 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 0.6 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 1.8 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.8 GO:0043295 glutathione binding(GO:0043295)
0.1 0.1 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 4.3 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.4 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 3.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 1.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 2.6 GO:0019905 syntaxin binding(GO:0019905)
0.0 16.1 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 3.4 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 1.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 1.6 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 1.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.3 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0070697 activin receptor binding(GO:0070697)
0.0 1.9 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.3 GO:0017069 snRNA binding(GO:0017069)
0.0 0.8 GO:0003774 motor activity(GO:0003774)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 3.4 GO:0001047 core promoter binding(GO:0001047)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771) methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.4 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.3 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.9 GO:0042393 histone binding(GO:0042393)
0.0 6.6 GO:0003712 transcription cofactor activity(GO:0003712)
0.0 0.5 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.1 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 1.0 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 2.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) polynucleotide phosphatase activity(GO:0098518)
0.0 0.5 GO:0008013 beta-catenin binding(GO:0008013)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 22.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.7 46.3 PID AURORA B PATHWAY Aurora B signaling
0.6 21.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.5 21.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.5 17.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.5 10.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.4 12.9 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.4 3.7 PID CD40 PATHWAY CD40/CD40L signaling
0.4 14.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.4 10.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.3 16.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.3 39.0 PID E2F PATHWAY E2F transcription factor network
0.3 17.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.3 15.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.3 11.3 PID MYC PATHWAY C-MYC pathway
0.2 2.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.2 14.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 11.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 7.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 13.3 PID NOTCH PATHWAY Notch signaling pathway
0.2 13.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.2 6.3 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.2 10.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 4.5 PID ALK1 PATHWAY ALK1 signaling events
0.1 7.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 2.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 7.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 2.8 PID REELIN PATHWAY Reelin signaling pathway
0.1 1.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 1.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 3.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 3.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 3.5 PID IL1 PATHWAY IL1-mediated signaling events
0.1 1.8 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 3.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 2.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 3.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 2.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 3.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 3.5 PID CDC42 PATHWAY CDC42 signaling events
0.1 11.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 5.0 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 1.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.4 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 2.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 3.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.7 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 22.8 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
1.3 20.9 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
1.2 22.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
1.1 29.5 REACTOME KINESINS Genes involved in Kinesins
0.9 23.9 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.9 20.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.9 5.2 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.9 18.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.8 13.9 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.8 11.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.8 82.2 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.7 10.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.7 42.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.7 24.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.6 16.1 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.6 22.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.6 4.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.6 44.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.6 6.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.5 18.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.5 19.9 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.5 9.9 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.5 15.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.5 15.2 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.4 7.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.4 41.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.4 8.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.4 11.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.4 9.7 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.4 6.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.3 6.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.3 5.6 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.3 12.7 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.3 8.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.3 9.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.3 10.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.3 18.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.3 6.2 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.3 3.2 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
0.3 3.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.3 4.6 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.3 5.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3 5.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.3 6.7 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.3 6.0 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.3 2.8 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.3 5.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.2 4.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 6.8 REACTOME INTERFERON SIGNALING Genes involved in Interferon Signaling
0.2 17.1 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.2 19.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.2 4.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 3.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 15.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 4.0 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.2 23.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.2 3.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 6.9 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.2 4.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 1.8 REACTOME OPSINS Genes involved in Opsins
0.2 2.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.2 4.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 2.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.2 10.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 3.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 14.7 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.1 7.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 4.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 5.4 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 3.4 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 0.9 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 2.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 15.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 2.9 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 4.2 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 2.8 REACTOME ASSEMBLY OF THE PRE REPLICATIVE COMPLEX Genes involved in Assembly of the pre-replicative complex
0.1 1.9 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.7 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.1 3.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 3.0 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 10.3 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 2.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 2.0 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 0.7 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.1 0.8 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 13.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 0.4 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 2.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 3.7 REACTOME TRANSLATION Genes involved in Translation
0.1 2.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 4.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.0 0.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.6 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 1.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.5 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.0 0.9 REACTOME PI 3K CASCADE Genes involved in PI-3K cascade
0.0 1.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis