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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for NFATC2_NFATC3

Z-value: 1.50

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Transcription factors associated with NFATC2_NFATC3

Gene Symbol Gene ID Gene Info
NFATC2
ENSG00000101096.15 nuclear factor of activated T cells 2
NFATC3
ENSG00000072736.14 nuclear factor of activated T cells 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFATC3hg19_v2_chr16_+_68119247_68119293-0.678.4e-30Click!

Activity profile of NFATC2_NFATC3 motif

Sorted Z-values of NFATC2_NFATC3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_91573132 44.23 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr12_-_91573249 41.61 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN
decorin
chr12_-_91573316 34.23 ENST00000393155.1
DCN
decorin
chr2_-_238322770 29.29 ENST00000472056.1
COL6A3
collagen, type VI, alpha 3
chr9_-_35691017 28.54 ENST00000378292.3
TPM2
tropomyosin 2 (beta)
chr1_+_86046433 28.07 ENST00000451137.2
CYR61
cysteine-rich, angiogenic inducer, 61
chr2_-_238322800 26.80 ENST00000392004.3
ENST00000433762.1
ENST00000347401.3
ENST00000353578.4
ENST00000346358.4
ENST00000392003.2
COL6A3
collagen, type VI, alpha 3
chr12_-_91539918 26.62 ENST00000548218.1
DCN
decorin
chr2_-_238323007 24.07 ENST00000295550.4
COL6A3
collagen, type VI, alpha 3
chr14_-_92413353 23.58 ENST00000556154.1
FBLN5
fibulin 5
chr12_-_9268707 23.28 ENST00000318602.7
A2M
alpha-2-macroglobulin
chr14_-_92413727 20.69 ENST00000267620.10
FBLN5
fibulin 5
chr17_+_20059302 19.65 ENST00000395530.2
SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr12_-_50616122 19.37 ENST00000552823.1
ENST00000552909.1
LIMA1
LIM domain and actin binding 1
chr8_-_13134045 16.66 ENST00000512044.2
DLC1
deleted in liver cancer 1
chr12_-_50616382 15.96 ENST00000552783.1
LIMA1
LIM domain and actin binding 1
chr2_-_163099885 14.98 ENST00000443424.1
FAP
fibroblast activation protein, alpha
chr2_-_163100045 14.65 ENST00000188790.4
FAP
fibroblast activation protein, alpha
chr2_-_190044480 14.62 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr16_-_3306587 14.58 ENST00000541159.1
ENST00000536379.1
ENST00000219596.1
ENST00000339854.4
MEFV
Mediterranean fever
chr7_+_20686946 14.21 ENST00000443026.2
ENST00000406935.1
ABCB5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr3_-_114035026 13.85 ENST00000570269.1
RP11-553L6.5
RP11-553L6.5
chr9_+_124062071 13.57 ENST00000373818.4
GSN
gelsolin
chr11_-_111794446 13.50 ENST00000527950.1
CRYAB
crystallin, alpha B
chr19_+_41509851 13.08 ENST00000593831.1
ENST00000330446.5
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr3_-_195310802 12.79 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr15_-_90892669 12.53 ENST00000412799.2
GABARAPL3
GABA(A) receptors associated protein like 3, pseudogene
chr5_-_42811986 12.32 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr8_+_98900132 11.88 ENST00000520016.1
MATN2
matrilin 2
chr5_-_42812143 11.83 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr15_+_93443419 11.75 ENST00000557381.1
ENST00000420239.2
CHD2
chromodomain helicase DNA binding protein 2
chr8_-_95274536 11.67 ENST00000297596.2
ENST00000396194.2
GEM
GTP binding protein overexpressed in skeletal muscle
chr5_+_135394840 11.47 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr7_+_134551583 10.95 ENST00000435928.1
CALD1
caldesmon 1
chr11_-_119293872 10.91 ENST00000524970.1
THY1
Thy-1 cell surface antigen
chr3_-_183273477 10.57 ENST00000341319.3
KLHL6
kelch-like family member 6
chr19_+_37998031 10.36 ENST00000586138.1
ENST00000588578.1
ENST00000587986.1
ZNF793
zinc finger protein 793
chr13_-_88323218 10.03 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
MIR4500HG
MIR4500 host gene (non-protein coding)
chr16_+_15528332 9.99 ENST00000566490.1
C16orf45
chromosome 16 open reading frame 45
chr21_+_27011584 9.82 ENST00000400532.1
ENST00000480456.1
ENST00000312957.5
JAM2
junctional adhesion molecule 2
chr15_+_63340647 9.74 ENST00000404484.4
TPM1
tropomyosin 1 (alpha)
chr3_-_123512688 9.52 ENST00000475616.1
MYLK
myosin light chain kinase
chr17_-_1389228 9.24 ENST00000438665.2
MYO1C
myosin IC
chr15_+_63340858 9.02 ENST00000560615.1
TPM1
tropomyosin 1 (alpha)
chr22_-_38380543 8.94 ENST00000396884.2
SOX10
SRY (sex determining region Y)-box 10
chr17_-_8263538 8.92 ENST00000535173.1
AC135178.1
HCG1985372; Uncharacterized protein; cDNA FLJ37541 fis, clone BRCAN2026340
chr8_+_80523321 8.85 ENST00000518111.1
STMN2
stathmin-like 2
chr15_+_96869165 8.82 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr15_-_65503801 8.70 ENST00000261883.4
CILP
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr1_-_150780757 8.65 ENST00000271651.3
CTSK
cathepsin K
chr15_+_63334831 8.63 ENST00000288398.6
ENST00000358278.3
ENST00000560445.1
ENST00000403994.3
ENST00000357980.4
ENST00000559556.1
ENST00000559397.1
ENST00000267996.7
ENST00000560970.1
TPM1
tropomyosin 1 (alpha)
chr6_+_31795506 8.59 ENST00000375650.3
HSPA1B
heat shock 70kDa protein 1B
chr12_-_95467267 8.54 ENST00000330677.7
NR2C1
nuclear receptor subfamily 2, group C, member 1
chr5_+_140186647 8.47 ENST00000512229.2
ENST00000356878.4
ENST00000530339.1
PCDHA4
protocadherin alpha 4
chrX_+_22056165 8.43 ENST00000535894.1
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr19_+_58095501 8.35 ENST00000536878.2
ENST00000597850.1
ENST00000597219.1
ENST00000598689.1
ENST00000599456.1
ENST00000307468.4
ZIK1
zinc finger protein interacting with K protein 1
chr15_-_37392086 8.33 ENST00000561208.1
MEIS2
Meis homeobox 2
chr15_+_63340734 8.28 ENST00000560959.1
TPM1
tropomyosin 1 (alpha)
chr6_+_151662815 8.14 ENST00000359755.5
AKAP12
A kinase (PRKA) anchor protein 12
chr8_-_110703819 8.14 ENST00000532779.1
ENST00000534578.1
SYBU
syntabulin (syntaxin-interacting)
chr1_+_162602244 7.97 ENST00000367922.3
ENST00000367921.3
DDR2
discoidin domain receptor tyrosine kinase 2
chr17_-_1389419 7.96 ENST00000575158.1
MYO1C
myosin IC
chrX_+_56259316 7.90 ENST00000468660.1
KLF8
Kruppel-like factor 8
chr10_+_128593978 7.87 ENST00000280333.6
DOCK1
dedicator of cytokinesis 1
chr17_+_59477233 7.79 ENST00000240328.3
TBX2
T-box 2
chr8_-_120685608 7.57 ENST00000427067.2
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr16_+_31483451 7.54 ENST00000565360.1
ENST00000361773.3
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr8_+_70404996 7.50 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr1_+_244816237 7.38 ENST00000302550.11
DESI2
desumoylating isopeptidase 2
chrX_-_17878827 7.28 ENST00000360011.1
RAI2
retinoic acid induced 2
chr4_+_41614909 7.14 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr19_-_36523709 7.13 ENST00000592017.1
ENST00000360535.4
CLIP3
CAP-GLY domain containing linker protein 3
chrY_-_15591485 7.07 ENST00000382896.4
ENST00000537580.1
ENST00000540140.1
ENST00000545955.1
ENST00000538878.1
UTY
ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
chr19_+_11658655 7.06 ENST00000588935.1
CNN1
calponin 1, basic, smooth muscle
chr17_-_38256973 6.97 ENST00000246672.3
NR1D1
nuclear receptor subfamily 1, group D, member 1
chr14_+_24837226 6.88 ENST00000554050.1
ENST00000554903.1
ENST00000554779.1
ENST00000250373.4
ENST00000553708.1
NFATC4
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
chr14_-_52535712 6.84 ENST00000216286.5
ENST00000541773.1
NID2
nidogen 2 (osteonidogen)
chr12_+_12938541 6.74 ENST00000356591.4
APOLD1
apolipoprotein L domain containing 1
chr4_+_55095264 6.72 ENST00000257290.5
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr18_+_23806437 6.71 ENST00000578121.1
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr5_+_140220769 6.68 ENST00000531613.1
ENST00000378123.3
PCDHA8
protocadherin alpha 8
chr16_+_55542910 6.65 ENST00000262134.5
LPCAT2
lysophosphatidylcholine acyltransferase 2
chr3_+_148447887 6.63 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr4_+_41258786 6.61 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr16_-_71610985 6.53 ENST00000355962.4
TAT
tyrosine aminotransferase
chr15_+_63354769 6.53 ENST00000558910.1
TPM1
tropomyosin 1 (alpha)
chr5_-_77844974 6.52 ENST00000515007.2
LHFPL2
lipoma HMGIC fusion partner-like 2
chr4_-_168155300 6.47 ENST00000541637.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr8_-_110704014 6.45 ENST00000529190.1
ENST00000422135.1
ENST00000419099.1
SYBU
syntabulin (syntaxin-interacting)
chr15_+_63340775 6.45 ENST00000559281.1
ENST00000317516.7
TPM1
tropomyosin 1 (alpha)
chr11_+_75273246 6.44 ENST00000526397.1
ENST00000529643.1
ENST00000525492.1
ENST00000530284.1
ENST00000532356.1
ENST00000524558.1
SERPINH1
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr12_+_10365404 6.44 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr6_-_52859046 6.44 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
GSTA4
glutathione S-transferase alpha 4
chr5_+_140772381 6.41 ENST00000398604.2
PCDHGA8
protocadherin gamma subfamily A, 8
chr22_-_19512893 6.36 ENST00000403084.1
ENST00000413119.2
CLDN5
claudin 5
chr9_+_103204553 6.29 ENST00000502978.1
ENST00000334943.6
MSANTD3-TMEFF1
TMEFF1
MSANTD3-TMEFF1 readthrough
transmembrane protein with EGF-like and two follistatin-like domains 1
chr6_+_86159821 6.27 ENST00000369651.3
NT5E
5'-nucleotidase, ecto (CD73)
chr1_+_46640750 6.22 ENST00000372003.1
TSPAN1
tetraspanin 1
chr2_+_46926326 6.01 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr5_+_131993856 5.91 ENST00000304506.3
IL13
interleukin 13
chr11_+_75273101 5.90 ENST00000533603.1
ENST00000358171.3
ENST00000526242.1
SERPINH1
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr16_+_56642041 5.86 ENST00000245185.5
MT2A
metallothionein 2A
chr6_-_11779840 5.82 ENST00000506810.1
ADTRP
androgen-dependent TFPI-regulating protein
chr10_+_74451883 5.81 ENST00000373053.3
ENST00000357157.6
MCU
mitochondrial calcium uniporter
chr2_+_234580525 5.73 ENST00000609637.1
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr14_+_32546274 5.70 ENST00000396582.2
ARHGAP5
Rho GTPase activating protein 5
chr7_+_150497491 5.67 ENST00000484928.1
TMEM176A
transmembrane protein 176A
chr14_+_65171099 5.61 ENST00000247226.7
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr12_-_104443890 5.57 ENST00000547583.1
ENST00000360814.4
ENST00000546851.1
GLT8D2
glycosyltransferase 8 domain containing 2
chr5_+_140864649 5.57 ENST00000306593.1
PCDHGC4
protocadherin gamma subfamily C, 4
chr6_+_43739697 5.56 ENST00000230480.6
VEGFA
vascular endothelial growth factor A
chr22_-_36220420 5.55 ENST00000473487.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr6_+_86159765 5.54 ENST00000369646.3
ENST00000257770.3
NT5E
5'-nucleotidase, ecto (CD73)
chr1_+_179712298 5.49 ENST00000341785.4
FAM163A
family with sequence similarity 163, member A
chr17_+_74372662 5.47 ENST00000591651.1
ENST00000545180.1
SPHK1
sphingosine kinase 1
chr20_+_19867150 5.46 ENST00000255006.6
RIN2
Ras and Rab interactor 2
chr16_+_66400533 5.44 ENST00000341529.3
CDH5
cadherin 5, type 2 (vascular endothelium)
chr16_-_66952742 5.32 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
CDH16
cadherin 16, KSP-cadherin
chr1_-_151319283 5.25 ENST00000392746.3
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr14_+_75536335 5.22 ENST00000554763.1
ENST00000439583.2
ENST00000526130.1
ENST00000525046.1
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr9_+_35538616 5.18 ENST00000455600.1
RUSC2
RUN and SH3 domain containing 2
chr1_+_54519242 5.18 ENST00000234827.1
TCEANC2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chrX_-_37706661 5.15 ENST00000432389.2
ENST00000378581.3
DYNLT3
dynein, light chain, Tctex-type 3
chr4_+_169418195 5.14 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chrX_+_84498989 5.14 ENST00000395402.1
ZNF711
zinc finger protein 711
chr14_+_75536280 5.12 ENST00000238686.8
ZC2HC1C
zinc finger, C2HC-type containing 1C
chrX_-_40506766 4.97 ENST00000378421.1
ENST00000440784.2
ENST00000327877.5
ENST00000378426.1
ENST00000378418.2
CXorf38
chromosome X open reading frame 38
chr5_+_132009675 4.96 ENST00000231449.2
ENST00000350025.2
IL4
interleukin 4
chr9_+_19049372 4.94 ENST00000380527.1
RRAGA
Ras-related GTP binding A
chr5_-_138210977 4.91 ENST00000274711.6
ENST00000521094.2
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr20_+_36149602 4.86 ENST00000062104.2
ENST00000346199.2
NNAT
neuronatin
chr5_-_41261540 4.86 ENST00000263413.3
C6
complement component 6
chr3_+_148415571 4.85 ENST00000497524.1
ENST00000349243.3
ENST00000542281.1
ENST00000418473.2
ENST00000404754.2
AGTR1
angiotensin II receptor, type 1
chr12_-_16758059 4.82 ENST00000261169.6
LMO3
LIM domain only 3 (rhombotin-like 2)
chr3_+_142442841 4.80 ENST00000476941.1
ENST00000273482.6
TRPC1
transient receptor potential cation channel, subfamily C, member 1
chr5_+_140762268 4.77 ENST00000518325.1
PCDHGA7
protocadherin gamma subfamily A, 7
chr8_-_38853990 4.77 ENST00000456845.2
ENST00000397070.2
ENST00000517872.1
ENST00000412303.1
ENST00000456397.2
TM2D2
TM2 domain containing 2
chr4_+_88571429 4.74 ENST00000339673.6
ENST00000282479.7
DMP1
dentin matrix acidic phosphoprotein 1
chr16_+_29674540 4.72 ENST00000436527.1
ENST00000360121.3
ENST00000449759.1
SPN
QPRT
sialophorin
quinolinate phosphoribosyltransferase
chr16_-_66952779 4.72 ENST00000570262.1
ENST00000394055.3
ENST00000299752.4
CDH16
cadherin 16, KSP-cadherin
chr1_-_68698222 4.70 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr9_+_137533615 4.68 ENST00000371817.3
COL5A1
collagen, type V, alpha 1
chrX_+_52780318 4.67 ENST00000375515.3
ENST00000276049.6
SSX2B
synovial sarcoma, X breakpoint 2B
chr12_-_16758304 4.66 ENST00000320122.6
LMO3
LIM domain only 3 (rhombotin-like 2)
chr18_-_500692 4.62 ENST00000400256.3
COLEC12
collectin sub-family member 12
chr2_+_234580499 4.62 ENST00000354728.4
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr3_-_167813132 4.61 ENST00000309027.4
GOLIM4
golgi integral membrane protein 4
chr10_+_105036909 4.55 ENST00000369849.4
INA
internexin neuronal intermediate filament protein, alpha
chr11_-_119187826 4.52 ENST00000264036.4
MCAM
melanoma cell adhesion molecule
chr14_-_89878369 4.52 ENST00000553840.1
ENST00000556916.1
FOXN3
forkhead box N3
chr1_+_82266053 4.51 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2
latrophilin 2
chr2_+_11696464 4.50 ENST00000234142.5
GREB1
growth regulation by estrogen in breast cancer 1
chr15_+_32933866 4.50 ENST00000300175.4
ENST00000413748.2
ENST00000494364.1
ENST00000497208.1
SCG5
secretogranin V (7B2 protein)
chr10_-_29923893 4.49 ENST00000355867.4
SVIL
supervillin
chr4_+_39408470 4.49 ENST00000257408.4
KLB
klotho beta
chr13_-_33780133 4.47 ENST00000399365.3
STARD13
StAR-related lipid transfer (START) domain containing 13
chr15_-_37391614 4.43 ENST00000219869.9
MEIS2
Meis homeobox 2
chr17_-_34257731 4.43 ENST00000431884.2
ENST00000425909.3
ENST00000394528.3
ENST00000430160.2
RDM1
RAD52 motif 1
chr15_+_74466744 4.39 ENST00000560862.1
ENST00000395118.1
ISLR
immunoglobulin superfamily containing leucine-rich repeat
chr4_-_186877806 4.38 ENST00000355634.5
SORBS2
sorbin and SH3 domain containing 2
chr2_-_206950781 4.38 ENST00000403263.1
INO80D
INO80 complex subunit D
chr2_-_227664474 4.35 ENST00000305123.5
IRS1
insulin receptor substrate 1
chr1_-_94703118 4.34 ENST00000260526.6
ENST00000370217.3
ARHGAP29
Rho GTPase activating protein 29
chr1_+_38022513 4.33 ENST00000296218.7
DNALI1
dynein, axonemal, light intermediate chain 1
chr7_+_108210012 4.33 ENST00000249356.3
DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr10_+_47746929 4.33 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2
AL603965.1
annexin A8-like 2
Protein LOC100996760
chr17_+_42925270 4.30 ENST00000253410.2
ENST00000587021.1
HIGD1B
HIG1 hypoxia inducible domain family, member 1B
chr7_-_92157760 4.30 ENST00000248633.4
PEX1
peroxisomal biogenesis factor 1
chr11_-_76381029 4.29 ENST00000407242.2
ENST00000421973.1
LRRC32
leucine rich repeat containing 32
chr1_-_109618566 4.25 ENST00000338366.5
TAF13
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
chr17_-_15522826 4.21 ENST00000395906.3
CDRT1
CMT1A duplicated region transcript 1
chr6_-_134495992 4.20 ENST00000475719.2
ENST00000367857.5
ENST00000237305.7
SGK1
serum/glucocorticoid regulated kinase 1
chr7_+_102553430 4.19 ENST00000339431.4
ENST00000249377.4
LRRC17
leucine rich repeat containing 17
chr7_-_122526799 4.19 ENST00000334010.7
ENST00000313070.7
CADPS2
Ca++-dependent secretion activator 2
chr15_+_43885252 4.17 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chrX_+_37208540 4.15 ENST00000466533.1
ENST00000542554.1
ENST00000543642.1
ENST00000484460.1
ENST00000449135.2
ENST00000463135.1
ENST00000465127.1
PRRG1
TM4SF2
proline rich Gla (G-carboxyglutamic acid) 1
Uncharacterized protein; cDNA FLJ59144, highly similar to Tetraspanin-7
chr11_+_64851729 4.14 ENST00000526791.1
ENST00000526945.1
ZFPL1
zinc finger protein-like 1
chr17_-_39041479 4.12 ENST00000167588.3
KRT20
keratin 20
chr5_+_140254884 4.09 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr1_-_161207953 4.07 ENST00000367982.4
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr6_+_31916733 4.05 ENST00000483004.1
CFB
complement factor B
chr12_+_54447637 4.04 ENST00000609810.1
ENST00000430889.2
HOXC4
HOXC4
homeobox C4
Homeobox protein Hox-C4
chr6_-_131384373 4.03 ENST00000392427.3
ENST00000525271.1
ENST00000527411.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr18_-_52989217 4.02 ENST00000570287.2
TCF4
transcription factor 4
chr9_-_13165457 4.01 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ
multiple PDZ domain protein
chr6_-_62996066 4.01 ENST00000281156.4
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr22_-_36236265 4.00 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr22_-_36236623 3.99 ENST00000405409.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr1_+_215747118 3.97 ENST00000448333.1
KCTD3
potassium channel tetramerization domain containing 3
chr7_+_120629653 3.95 ENST00000450913.2
ENST00000340646.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr11_-_10590238 3.95 ENST00000256178.3
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr15_+_43985084 3.94 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr14_+_65171315 3.93 ENST00000394691.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr11_+_22696314 3.92 ENST00000532398.1
ENST00000433790.1
GAS2
growth arrest-specific 2
chr10_+_114710516 3.89 ENST00000542695.1
ENST00000346198.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chrX_+_44732757 3.87 ENST00000377967.4
ENST00000536777.1
ENST00000382899.4
ENST00000543216.1
KDM6A
lysine (K)-specific demethylase 6A
chr17_-_39093672 3.86 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr11_-_10590118 3.84 ENST00000529598.1
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr12_-_76425368 3.84 ENST00000602540.1
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr7_+_127881325 3.84 ENST00000308868.4
LEP
leptin

Network of associatons between targets according to the STRING database.

First level regulatory network of NFATC2_NFATC3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
12.2 146.7 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
7.4 29.6 GO:0097325 melanocyte proliferation(GO:0097325)
6.1 48.6 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
4.9 14.6 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
4.8 19.3 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
4.3 12.8 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
3.9 11.7 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
3.7 44.3 GO:0048251 elastic fiber assembly(GO:0048251)
3.6 10.9 GO:0071557 histone H3-K27 demethylation(GO:0071557)
3.6 10.9 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
3.6 14.2 GO:0048749 compound eye development(GO:0048749)
3.1 28.1 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
3.0 11.8 GO:0046086 adenosine biosynthetic process(GO:0046086)
2.9 11.5 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
2.8 11.3 GO:2000320 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
2.7 13.6 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
2.5 7.6 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
2.5 12.3 GO:0038091 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
2.4 14.7 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
2.4 7.3 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
2.3 7.0 GO:0060086 circadian temperature homeostasis(GO:0060086)
2.3 13.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
2.2 8.9 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
2.2 8.8 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
2.2 8.8 GO:0009956 radial pattern formation(GO:0009956)
2.2 6.6 GO:0007412 axon target recognition(GO:0007412)
2.1 8.6 GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
2.1 6.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
2.1 6.2 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
1.9 7.5 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
1.8 5.5 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
1.8 23.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
1.8 5.5 GO:0046521 sphingoid catabolic process(GO:0046521)
1.7 8.6 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
1.7 6.7 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
1.6 9.7 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
1.6 6.4 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
1.6 9.5 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
1.6 14.2 GO:0051552 flavone metabolic process(GO:0051552)
1.6 7.8 GO:0007521 muscle cell fate determination(GO:0007521)
1.6 6.2 GO:0019249 lactate biosynthetic process(GO:0019249)
1.5 12.3 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
1.5 7.6 GO:1903976 negative regulation of glial cell migration(GO:1903976)
1.5 16.7 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
1.5 11.8 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
1.5 5.9 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
1.4 7.1 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
1.4 8.5 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
1.3 3.8 GO:0045210 FasL biosynthetic process(GO:0045210)
1.3 3.8 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
1.2 3.7 GO:0061073 ciliary body morphogenesis(GO:0061073)
1.2 4.9 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
1.2 9.5 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
1.2 4.7 GO:0002884 regulation of type IV hypersensitivity(GO:0001807) negative regulation of hypersensitivity(GO:0002884)
1.2 87.8 GO:0030574 collagen catabolic process(GO:0030574)
1.1 2.3 GO:0045168 cell-cell signaling involved in cell fate commitment(GO:0045168)
1.1 4.3 GO:0021564 vagus nerve development(GO:0021564)
1.0 4.2 GO:0048539 bone marrow development(GO:0048539)
1.0 3.1 GO:0044278 cell wall disruption in other organism(GO:0044278)
1.0 12.4 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
1.0 4.1 GO:0003409 optic cup structural organization(GO:0003409)
1.0 8.0 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
1.0 8.8 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
1.0 3.9 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
1.0 13.7 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
1.0 10.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
1.0 5.8 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
1.0 6.8 GO:0006572 tyrosine catabolic process(GO:0006572)
1.0 1.0 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.9 7.5 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.9 13.1 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.9 15.8 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.9 3.7 GO:0009386 translational attenuation(GO:0009386)
0.9 5.5 GO:0070170 regulation of tooth mineralization(GO:0070170)
0.9 4.5 GO:0061042 vascular wound healing(GO:0061042)
0.9 4.5 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.9 2.7 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.9 3.5 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.9 3.5 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.9 3.4 GO:0007525 somatic muscle development(GO:0007525)
0.8 4.2 GO:1990504 dense core granule exocytosis(GO:1990504)
0.8 3.3 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.8 4.9 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.8 10.5 GO:0002467 germinal center formation(GO:0002467)
0.8 3.2 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.8 1.6 GO:0060061 Spemann organizer formation(GO:0060061) canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.8 3.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.8 2.3 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.8 10.5 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.8 13.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.7 1.5 GO:0090035 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.7 5.1 GO:0070305 response to cGMP(GO:0070305)
0.7 5.0 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.7 2.1 GO:0048867 stem cell fate determination(GO:0048867)
0.7 2.8 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.7 1.4 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.7 7.4 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.7 35.3 GO:0031529 ruffle organization(GO:0031529)
0.6 1.9 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.6 1.9 GO:0016095 polyprenol catabolic process(GO:0016095)
0.6 2.5 GO:0019087 transformation of host cell by virus(GO:0019087)
0.6 8.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.6 5.6 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.6 7.4 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.6 2.5 GO:0021997 response to chlorate(GO:0010157) neural plate axis specification(GO:0021997)
0.6 2.4 GO:1905229 cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.6 2.4 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.6 3.5 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.6 5.8 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.6 2.3 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.6 2.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.6 2.9 GO:0042095 interferon-gamma biosynthetic process(GO:0042095) regulation of interferon-gamma biosynthetic process(GO:0045072) positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.6 2.3 GO:0089700 protein kinase D signaling(GO:0089700)
0.6 1.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.6 6.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.6 4.5 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.6 2.8 GO:1904073 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.5 2.2 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.5 2.7 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.5 5.9 GO:0006600 creatine metabolic process(GO:0006600)
0.5 3.2 GO:2000330 positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.5 1.6 GO:0035993 subthalamic nucleus development(GO:0021763) deltoid tuberosity development(GO:0035993) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578) cell proliferation involved in outflow tract morphogenesis(GO:0061325)
0.5 4.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.5 2.6 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.5 1.6 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.5 3.6 GO:0010269 response to selenium ion(GO:0010269)
0.5 2.0 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.5 1.5 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.5 2.5 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.5 2.5 GO:0089712 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.5 4.9 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.5 4.9 GO:0009249 protein lipoylation(GO:0009249)
0.5 4.8 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.5 1.4 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.5 2.4 GO:0006041 glucosamine metabolic process(GO:0006041) glucose 1-phosphate metabolic process(GO:0019255)
0.5 1.9 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.5 7.0 GO:0042574 retinal metabolic process(GO:0042574)
0.5 3.2 GO:0016102 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.5 4.6 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.4 1.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.4 1.3 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413)
0.4 1.7 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.4 3.0 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.4 2.5 GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.4 2.5 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.4 0.8 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.4 3.2 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.4 1.2 GO:0071288 cellular response to mercury ion(GO:0071288)
0.4 11.2 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.4 1.2 GO:1902617 response to fluoride(GO:1902617)
0.4 65.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.4 28.1 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.4 3.2 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.4 4.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.4 2.3 GO:0060174 limb bud formation(GO:0060174)
0.4 1.5 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.4 1.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.4 8.7 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.4 3.3 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.4 2.6 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.4 4.0 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.4 1.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.4 3.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.3 5.6 GO:0008584 gonad development(GO:0008406) male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.3 4.5 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.3 4.1 GO:0045109 intermediate filament organization(GO:0045109)
0.3 2.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.3 3.1 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.3 2.4 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.3 7.5 GO:0033622 integrin activation(GO:0033622)
0.3 1.3 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.3 1.0 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.3 2.3 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.3 2.0 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.3 0.7 GO:0030259 lipid glycosylation(GO:0030259)
0.3 1.0 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.3 2.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.3 2.9 GO:0070307 lens fiber cell development(GO:0070307)
0.3 2.6 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.3 3.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.3 0.3 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.3 2.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.3 6.9 GO:0003334 keratinocyte development(GO:0003334)
0.3 1.2 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.3 1.5 GO:0015722 canalicular bile acid transport(GO:0015722)
0.3 1.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.3 3.6 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.3 3.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.3 1.2 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.3 1.7 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.3 12.4 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.3 1.4 GO:0015840 urea transport(GO:0015840)
0.3 1.7 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.3 4.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.3 2.5 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.3 2.3 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.3 3.5 GO:0060850 regulation of transcription involved in cell fate commitment(GO:0060850)
0.3 0.5 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.3 1.8 GO:0046485 ether lipid metabolic process(GO:0046485)
0.3 1.3 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.3 2.0 GO:1901374 acetate ester transport(GO:1901374)
0.3 1.0 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.2 1.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 3.5 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.2 16.3 GO:0031016 pancreas development(GO:0031016)
0.2 0.7 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.2 0.7 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2 1.5 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.2 0.7 GO:0050917 sensory perception of umami taste(GO:0050917)
0.2 0.2 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.2 1.4 GO:0038161 prolactin signaling pathway(GO:0038161)
0.2 3.8 GO:0005513 detection of calcium ion(GO:0005513)
0.2 0.9 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.2 1.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.2 3.4 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.2 2.0 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.2 1.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.2 6.3 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.2 6.4 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.2 0.6 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.2 3.8 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.2 1.0 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.2 1.7 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.2 4.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 1.9 GO:0052695 cellular glucuronidation(GO:0052695)
0.2 1.5 GO:0098856 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.2 10.4 GO:0031102 neuron projection regeneration(GO:0031102)
0.2 1.5 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.2 2.6 GO:0060047 heart process(GO:0003015) heart contraction(GO:0060047)
0.2 6.0 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.2 1.6 GO:0051026 chiasma assembly(GO:0051026)
0.2 0.5 GO:0060581 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.2 1.2 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
0.2 1.7 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 4.0 GO:0071711 basement membrane organization(GO:0071711)
0.2 2.3 GO:0046320 regulation of fatty acid oxidation(GO:0046320)
0.2 1.9 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.2 1.5 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.2 0.5 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.2 0.6 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.2 2.0 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.2 0.9 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.2 0.5 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.1 2.1 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.1 0.9 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 2.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 6.3 GO:0016486 peptide hormone processing(GO:0016486)
0.1 2.2 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 2.5 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.1 3.3 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.1 0.8 GO:0038042 dimeric G-protein coupled receptor signaling pathway(GO:0038042)
0.1 1.4 GO:2000020 positive regulation of male gonad development(GO:2000020)
0.1 2.3 GO:0006590 thyroid hormone generation(GO:0006590)
0.1 7.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 6.6 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 1.1 GO:0090527 actin filament reorganization(GO:0090527)
0.1 3.9 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 1.2 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.1 5.1 GO:0048706 embryonic skeletal system development(GO:0048706)
0.1 0.7 GO:0060290 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) transdifferentiation(GO:0060290) negative regulation of lung blood pressure(GO:0061767)
0.1 1.1 GO:0048665 neuron fate specification(GO:0048665)
0.1 4.4 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.1 1.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.2 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.1 2.5 GO:0017144 drug metabolic process(GO:0017144)
0.1 7.4 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1 2.2 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 3.1 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.1 8.8 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 1.0 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 3.0 GO:0030488 tRNA methylation(GO:0030488)
0.1 1.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 1.3 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 2.0 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 8.9 GO:0002062 chondrocyte differentiation(GO:0002062)
0.1 3.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 3.3 GO:0007160 cell-matrix adhesion(GO:0007160)
0.1 3.4 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 0.8 GO:0099612 protein localization to axon(GO:0099612)
0.1 1.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.5 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 3.6 GO:0046710 GDP metabolic process(GO:0046710)
0.1 1.3 GO:0046839 phospholipid dephosphorylation(GO:0046839) phosphatidylinositol dephosphorylation(GO:0046856)
0.1 4.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 1.9 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 5.9 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.1 0.4 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 3.5 GO:0008038 neuron recognition(GO:0008038)
0.1 1.3 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.1 0.8 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 7.0 GO:0032508 DNA duplex unwinding(GO:0032508)
0.1 3.0 GO:0005980 glycogen catabolic process(GO:0005980)
0.1 3.3 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.1 2.7 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 1.1 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.1 0.4 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.1 1.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 1.0 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 2.1 GO:0007129 synapsis(GO:0007129)
0.1 0.9 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 3.6 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 7.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 3.3 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 1.2 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.7 GO:0060539 diaphragm development(GO:0060539)
0.1 2.3 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.6 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 1.3 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 3.7 GO:0006024 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.1 1.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 1.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 2.7 GO:0006970 response to osmotic stress(GO:0006970)
0.1 1.8 GO:1901185 negative regulation of ERBB signaling pathway(GO:1901185)
0.1 0.3 GO:0008218 bioluminescence(GO:0008218)
0.1 0.6 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 2.2 GO:0042472 inner ear morphogenesis(GO:0042472)
0.0 1.8 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 1.8 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:0097152 mesenchymal cell apoptotic process(GO:0097152)
0.0 1.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 2.0 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.4 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.1 GO:0006566 threonine metabolic process(GO:0006566)
0.0 1.4 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0 2.8 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.5 GO:0031424 keratinization(GO:0031424)
0.0 0.3 GO:0032930 positive regulation of superoxide anion generation(GO:0032930)
0.0 0.2 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 2.2 GO:1990748 cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.7 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 1.2 GO:0048705 skeletal system morphogenesis(GO:0048705)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 1.4 GO:0007586 digestion(GO:0007586)
0.0 1.2 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 2.3 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.5 GO:0043542 endothelial cell migration(GO:0043542)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.7 GO:0060976 coronary vasculature development(GO:0060976)
0.0 1.1 GO:0051216 cartilage development(GO:0051216)
0.0 1.1 GO:0045995 regulation of embryonic development(GO:0045995)
0.0 0.1 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581) negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212) neurotransmitter receptor metabolic process(GO:0045213)
0.0 1.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.1 GO:0007498 mesoderm development(GO:0007498)
0.0 0.6 GO:0015701 bicarbonate transport(GO:0015701)
0.0 1.3 GO:0050796 regulation of insulin secretion(GO:0050796)
0.0 1.5 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 3.6 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 1.6 GO:0002576 platelet degranulation(GO:0002576)
0.0 1.0 GO:0070268 cornification(GO:0070268)
0.0 0.4 GO:0001578 microtubule bundle formation(GO:0001578)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
16.2 226.8 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
6.4 19.3 GO:0005588 collagen type V trimer(GO:0005588)
4.4 44.3 GO:0071953 elastic fiber(GO:0071953)
4.3 17.2 GO:0045160 myosin I complex(GO:0045160)
4.1 77.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
2.7 29.6 GO:0071438 invadopodium membrane(GO:0071438)
1.6 24.5 GO:0030478 actin cap(GO:0030478)
1.6 11.4 GO:0036021 endolysosome lumen(GO:0036021)
1.5 5.8 GO:1990246 uniplex complex(GO:1990246)
1.3 3.8 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
1.3 6.3 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
1.1 4.6 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
1.1 14.6 GO:0097433 dense body(GO:0097433)
0.9 4.3 GO:0005899 insulin receptor complex(GO:0005899)
0.8 13.5 GO:0097512 cardiac myofibril(GO:0097512)
0.8 13.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.8 11.6 GO:0008091 spectrin(GO:0008091)
0.8 4.9 GO:1990130 EGO complex(GO:0034448) Iml1 complex(GO:1990130) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.8 4.9 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.8 6.1 GO:0005593 FACIT collagen trimer(GO:0005593)
0.7 4.9 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.7 1.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.7 7.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.6 4.5 GO:0036449 microtubule minus-end(GO:0036449)
0.6 44.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.6 2.4 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.6 2.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.6 2.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.5 6.0 GO:0005614 interstitial matrix(GO:0005614)
0.5 4.9 GO:0005579 membrane attack complex(GO:0005579)
0.5 2.6 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.5 18.1 GO:0000421 autophagosome membrane(GO:0000421)
0.5 1.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.5 1.9 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.5 3.2 GO:0097427 microtubule bundle(GO:0097427)
0.4 1.3 GO:0043159 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159)
0.4 12.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.4 2.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.4 11.7 GO:0051233 spindle midzone(GO:0051233)
0.4 43.5 GO:0005604 basement membrane(GO:0005604)
0.4 1.5 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.4 1.4 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.3 19.2 GO:0016235 aggresome(GO:0016235)
0.3 2.6 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.3 8.9 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.3 2.5 GO:0044294 dendritic growth cone(GO:0044294)
0.3 3.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.3 4.6 GO:0005883 neurofilament(GO:0005883)
0.3 5.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.3 2.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.3 2.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.3 8.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.3 7.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.3 7.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.3 0.5 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.3 27.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.3 1.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.3 2.5 GO:0005916 fascia adherens(GO:0005916)
0.2 3.4 GO:0035102 PRC1 complex(GO:0035102)
0.2 3.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 6.5 GO:0005581 collagen trimer(GO:0005581)
0.2 0.2 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.2 1.4 GO:0043083 synaptic cleft(GO:0043083)
0.2 61.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2 9.7 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.2 0.8 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.2 5.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 4.1 GO:0030286 dynein complex(GO:0030286)
0.2 0.6 GO:0016013 syntrophin complex(GO:0016013)
0.2 7.4 GO:1904115 axon cytoplasm(GO:1904115)
0.2 4.8 GO:1990752 microtubule end(GO:1990752)
0.2 11.8 GO:0005796 Golgi lumen(GO:0005796)
0.2 13.5 GO:0005811 lipid particle(GO:0005811)
0.2 12.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.2 3.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 10.2 GO:0005776 autophagosome(GO:0005776)
0.1 11.6 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 2.0 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 2.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 12.5 GO:0005882 intermediate filament(GO:0005882)
0.1 3.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 14.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 0.7 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 11.6 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 4.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 16.5 GO:0005795 Golgi stack(GO:0005795)
0.1 7.9 GO:0005902 microvillus(GO:0005902)
0.1 2.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.5 GO:0031310 intrinsic component of endosome membrane(GO:0031302) intrinsic component of vacuolar membrane(GO:0031310)
0.1 12.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 3.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 1.1 GO:0000815 ESCRT III complex(GO:0000815)
0.1 19.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.1 2.0 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 4.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.5 GO:0016342 catenin complex(GO:0016342)
0.1 1.3 GO:0043073 germ cell nucleus(GO:0043073)
0.1 0.9 GO:0032982 myosin filament(GO:0032982)
0.1 0.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 2.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 8.9 GO:0005923 bicellular tight junction(GO:0005923)
0.1 11.7 GO:0030018 Z disc(GO:0030018)
0.1 11.3 GO:0005938 cell cortex(GO:0005938)
0.1 0.6 GO:0033391 chromatoid body(GO:0033391)
0.1 0.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 18.6 GO:0043025 neuronal cell body(GO:0043025)
0.1 2.9 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.2 GO:0045179 apical cortex(GO:0045179)
0.1 4.9 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.7 GO:0005922 connexon complex(GO:0005922)
0.1 2.5 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 4.2 GO:0042734 presynaptic membrane(GO:0042734)
0.1 3.5 GO:0043195 terminal bouton(GO:0043195)
0.1 1.5 GO:0043198 dendritic shaft(GO:0043198)
0.1 1.8 GO:0044291 cell-cell contact zone(GO:0044291)
0.1 10.3 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.9 GO:0030057 desmosome(GO:0030057)
0.0 1.4 GO:0031904 endosome lumen(GO:0031904)
0.0 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 65.6 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 1.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.5 GO:0015030 Cajal body(GO:0015030)
0.0 1.5 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.8 23.3 GO:0019959 interleukin-8 binding(GO:0019959)
3.8 11.5 GO:0001596 angiotensin type I receptor activity(GO:0001596)
3.6 10.9 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
2.7 197.4 GO:0050840 extracellular matrix binding(GO:0050840)
2.2 6.7 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
2.2 6.7 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
2.2 6.5 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
2.1 12.9 GO:0004882 androgen receptor activity(GO:0004882)
2.0 14.2 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
1.9 9.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.9 7.6 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
1.9 7.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.8 7.1 GO:0097001 ceramide binding(GO:0097001)
1.7 6.6 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
1.6 9.7 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
1.6 8.0 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
1.6 4.7 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
1.5 1.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.5 29.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
1.4 5.7 GO:0005134 interleukin-2 receptor binding(GO:0005134)
1.4 10.9 GO:0034235 GPI anchor binding(GO:0034235)
1.4 4.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
1.3 6.3 GO:0030348 syntaxin-3 binding(GO:0030348)
1.2 8.7 GO:0004035 alkaline phosphatase activity(GO:0004035)
1.2 11.6 GO:0042731 PH domain binding(GO:0042731)
1.2 3.5 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
1.1 13.6 GO:0045159 myosin II binding(GO:0045159)
1.1 4.5 GO:0008422 beta-glucosidase activity(GO:0008422)
1.1 3.4 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
1.1 3.3 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
1.1 11.8 GO:0008253 5'-nucleotidase activity(GO:0008253)
1.0 4.0 GO:0005502 11-cis retinal binding(GO:0005502)
0.9 91.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.9 7.5 GO:0048495 Roundabout binding(GO:0048495)
0.9 5.5 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.9 97.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.9 31.9 GO:0001972 retinoic acid binding(GO:0001972)
0.9 2.7 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.9 3.5 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.8 3.4 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.8 10.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.8 3.3 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.8 12.8 GO:0008179 adenylate cyclase binding(GO:0008179)
0.8 2.4 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.8 3.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.8 3.0 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.8 1.5 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.8 3.8 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.7 1.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.7 5.9 GO:0004111 creatine kinase activity(GO:0004111)
0.7 9.6 GO:0001968 fibronectin binding(GO:0001968)
0.7 15.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.7 28.4 GO:0003785 actin monomer binding(GO:0003785)
0.7 13.1 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.7 2.0 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.7 3.3 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.6 1.9 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.6 2.5 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.6 3.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.6 6.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.6 33.0 GO:0042169 SH2 domain binding(GO:0042169)
0.6 3.7 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.6 3.0 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.6 1.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.6 2.3 GO:0035473 lipase binding(GO:0035473)
0.6 4.6 GO:0005534 galactose binding(GO:0005534)
0.6 14.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.5 3.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.5 10.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.5 3.7 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.5 3.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.5 10.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.5 1.6 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.5 13.2 GO:0005523 tropomyosin binding(GO:0005523)
0.5 15.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.5 3.5 GO:0008142 oxysterol binding(GO:0008142)
0.5 2.0 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.5 4.5 GO:0070492 oligosaccharide binding(GO:0070492)
0.5 2.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.5 7.0 GO:0001222 transcription corepressor binding(GO:0001222)
0.5 2.5 GO:0004974 leukotriene receptor activity(GO:0004974)
0.5 2.5 GO:0097108 hedgehog family protein binding(GO:0097108)
0.5 1.9 GO:0035939 microsatellite binding(GO:0035939)
0.5 6.7 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.5 3.3 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.5 6.4 GO:0030957 Tat protein binding(GO:0030957)
0.5 6.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.4 4.4 GO:0046870 cadmium ion binding(GO:0046870)
0.4 1.3 GO:1990254 keratin filament binding(GO:1990254)
0.4 3.9 GO:0004969 histamine receptor activity(GO:0004969)
0.4 6.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.4 5.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.4 2.5 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.4 4.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.4 2.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.4 2.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.4 5.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.4 2.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.4 4.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.4 1.5 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.4 7.5 GO:0005112 Notch binding(GO:0005112)
0.3 3.4 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.3 2.4 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.3 3.4 GO:0030274 LIM domain binding(GO:0030274)
0.3 2.0 GO:0004522 ribonuclease A activity(GO:0004522)
0.3 2.7 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.3 1.0 GO:1904288 BAT3 complex binding(GO:1904288)
0.3 1.9 GO:0030492 hemoglobin binding(GO:0030492)
0.3 1.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.3 7.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.3 24.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.3 1.2 GO:0050692 DBD domain binding(GO:0050692)
0.3 2.0 GO:0004126 cytidine deaminase activity(GO:0004126)
0.3 3.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.3 1.5 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.3 0.9 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.3 3.1 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.3 1.4 GO:0004925 prolactin receptor activity(GO:0004925)
0.3 5.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.3 1.7 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3 1.4 GO:0031708 endothelin B receptor binding(GO:0031708)
0.3 3.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.3 2.5 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.3 2.2 GO:0017166 vinculin binding(GO:0017166)
0.3 5.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.3 7.9 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.3 5.1 GO:0005537 mannose binding(GO:0005537)
0.3 12.0 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.3 2.4 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 1.3 GO:0005113 patched binding(GO:0005113)
0.3 0.5 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.3 1.8 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.3 1.3 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.3 9.2 GO:0005518 collagen binding(GO:0005518)
0.3 36.0 GO:0005178 integrin binding(GO:0005178)
0.2 7.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.2 3.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.2 7.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.2 8.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 1.7 GO:0051525 NFAT protein binding(GO:0051525)
0.2 4.3 GO:0051787 misfolded protein binding(GO:0051787)
0.2 0.7 GO:0000035 acyl binding(GO:0000035)
0.2 2.4 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.2 1.0 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.2 11.9 GO:0032934 cholesterol binding(GO:0015485) sterol binding(GO:0032934)
0.2 2.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.2 5.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.2 35.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 0.6 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.2 0.6 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.2 0.6 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.2 2.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 7.2 GO:0004177 aminopeptidase activity(GO:0004177)
0.2 3.9 GO:0042166 acetylcholine binding(GO:0042166)
0.2 6.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2 2.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.2 1.2 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.2 2.0 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.2 2.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 1.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 3.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.2 8.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 1.5 GO:0004707 MAP kinase activity(GO:0004707)
0.1 11.1 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 3.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.7 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 2.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 3.9 GO:0001848 complement binding(GO:0001848)
0.1 1.5 GO:0031419 cobalamin binding(GO:0031419)
0.1 2.2 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 6.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.9 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 2.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.6 GO:0042923 neuropeptide binding(GO:0042923)
0.1 0.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 8.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 0.3 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.1 1.7 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 3.1 GO:0005109 frizzled binding(GO:0005109)
0.1 0.4 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.7 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1 3.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.8 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 2.9 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.1 GO:0051087 chaperone binding(GO:0051087)
0.1 5.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 2.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 8.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 10.5 GO:0005179 hormone activity(GO:0005179)
0.1 1.7 GO:0071837 HMG box domain binding(GO:0071837)
0.1 1.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 1.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 1.0 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.9 GO:0070700 BMP receptor binding(GO:0070700)
0.1 1.5 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 2.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 2.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 2.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 1.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 5.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.0 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.5 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 1.7 GO:0002020 protease binding(GO:0002020)
0.1 3.1 GO:0070851 growth factor receptor binding(GO:0070851)
0.1 1.5 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 5.0 GO:0008201 heparin binding(GO:0008201)
0.1 1.7 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.1 10.6 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 2.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.3 GO:0005080 protein kinase C binding(GO:0005080)
0.0 2.0 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.6 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 1.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 9.7 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.7 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.7 GO:0070402 NADPH binding(GO:0070402)
0.0 3.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 2.0 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.8 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.6 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 5.8 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.1 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.6 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.7 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.0 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 8.6 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.5 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 161.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
2.3 109.2 NABA COLLAGENS Genes encoding collagen proteins
1.1 71.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.6 5.9 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.5 2.2 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.5 2.7 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.4 10.7 PID AP1 PATHWAY AP-1 transcription factor network
0.4 79.2 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.4 26.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.4 14.0 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.3 11.8 PID S1P S1P2 PATHWAY S1P2 pathway
0.3 14.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.3 9.8 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.3 10.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.3 3.2 PID S1P S1P3 PATHWAY S1P3 pathway
0.3 1.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.3 6.4 ST GA12 PATHWAY G alpha 12 Pathway
0.2 2.3 PID IGF1 PATHWAY IGF1 pathway
0.2 3.8 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.2 58.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 6.8 PID IL27 PATHWAY IL27-mediated signaling events
0.2 9.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.2 14.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 5.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.2 8.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.2 7.8 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.2 7.7 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.2 7.9 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.2 8.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.2 9.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.2 3.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 3.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 9.5 PID AURORA B PATHWAY Aurora B signaling
0.2 14.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 3.7 PID INSULIN PATHWAY Insulin Pathway
0.1 4.5 PID FGF PATHWAY FGF signaling pathway
0.1 5.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 9.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 2.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 3.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 4.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 16.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 6.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 2.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 3.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 5.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.6 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 4.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 1.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 1.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 1.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 1.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 1.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 0.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 2.2 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.9 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.0 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.9 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 142.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
1.8 119.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
1.3 85.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
1.3 1.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
1.2 23.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
1.1 11.8 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.7 13.1 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.7 9.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.6 12.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.6 15.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.5 17.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.5 8.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.5 2.3 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.4 4.9 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.4 14.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.4 8.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.4 3.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.3 5.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.3 4.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.3 4.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.3 6.8 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.3 27.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.3 6.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.3 6.5 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.3 3.8 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.3 6.7 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.3 4.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 6.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.2 5.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 4.8 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.2 4.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.2 3.9 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 7.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 3.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 6.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 2.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.2 10.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 7.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 2.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 6.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 6.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 1.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.2 2.6 REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.2 4.9 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 4.9 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.2 2.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 2.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.9 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 3.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 2.2 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 2.7 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 0.9 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 2.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.8 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 9.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 3.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 2.0 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.1 4.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 2.7 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 2.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 2.9 REACTOME SHC MEDIATED CASCADE Genes involved in SHC-mediated cascade
0.1 1.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.9 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 3.0 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 2.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 13.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 4.2 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 1.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 1.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 7.8 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 0.7 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 1.7 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 0.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.6 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 2.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 2.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 1.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.4 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 1.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 9.3 REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.0 2.0 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 3.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.4 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 2.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.9 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 1.1 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis