Motif ID: ATF4.p2

Z-value: 1.267


Transcription factors associated with ATF4.p2:

Gene SymbolEntrez IDGene Name
ATF4 468 activating transcription factor 4 (tax-responsive enhancer element B67)



Activity profile for motif ATF4.p2.

activity profile for motif ATF4.p2


Sorted Z-values histogram for motif ATF4.p2

Sorted Z-values for motif ATF4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_1892157 2.283 NM_001319
CSNK1G2
casein kinase 1, gamma 2
chr19_+_1892184 2.212 CSNK1G2
casein kinase 1, gamma 2
chr20_+_33667160 1.716 NM_003116
SPAG4
sperm associated antigen 4
chr6_+_26312758 1.577 NM_003545
HIST1H4E
histone cluster 1, H4e
chr17_+_38831874 1.440 NM_001661
ARL4D
ADP-ribosylation factor-like 4D
chr22_+_20101661 1.432 NM_015094
HIC2
hypermethylated in cancer 2
chr3_+_38181972 1.258 NM_005109
OXSR1
oxidative-stress responsive 1
chr16_-_3008162 1.216 NM_021195
CLDN6
claudin 6
chr1_-_243092581 1.195 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr22_+_19601619 1.170 NM_005207
CRKL
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr19_+_16048306 1.164 TPM4
tropomyosin 4
chr22_+_36927884 1.155 NM_001161572
NM_001161574
NM_012323
MAFF


v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)


chr8_+_23442331 1.146 SLC25A37
solute carrier family 25, member 37
chr8_+_98857190 1.125 LAPTM4B
lysosomal protein transmembrane 4 beta
chr4_-_8493327 1.105 NM_001101667
NM_003501
ACOX3

acyl-CoA oxidase 3, pristanoyl

chr2_+_108702338 1.101 NM_006267
RANBP2
RAN binding protein 2
chr1_+_29435534 1.100 NM_001195001
NM_005704
NM_133177
NM_133178
PTPRU



protein tyrosine phosphatase, receptor type, U



chr8_+_23442307 1.092 NM_016612
SLC25A37
solute carrier family 25, member 37
chr8_+_23442413 1.087 SLC25A37
solute carrier family 25, member 37
chr22_+_19601721 1.073 CRKL
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr19_+_16048266 1.060 TPM4
tropomyosin 4
chr21_+_44033871 1.048 RRP1
ribosomal RNA processing 1 homolog (S. cerevisiae)
chr19_+_16048315 1.045 TPM4
tropomyosin 4
chr1_+_210848726 1.033 ATF3
activating transcription factor 3
chr22_+_36928011 1.030 MAFF
v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr1_+_148090804 1.023 NM_021059
NM_001005464
HIST2H3C
HIST2H3A
histone cluster 2, H3c
histone cluster 2, H3a
chr1_+_210848763 1.021 ATF3
activating transcription factor 3
chr6_+_47553399 1.006 NM_012120
CD2AP
CD2-associated protein
chr1_+_210848592 0.964 NM_001040619
NM_001674
ATF3

activating transcription factor 3

chr1_+_9571518 0.950 NM_001010866
NM_001130924
TMEM201

transmembrane protein 201

chr6_+_139497933 0.917 NM_016217
HECA
headcase homolog (Drosophila)
chr5_+_56505412 0.887 NM_022913
GPBP1
GC-rich promoter binding protein 1
chr5_+_78568094 0.881


chr21_+_44033821 0.881 NM_003683
RRP1
ribosomal RNA processing 1 homolog (S. cerevisiae)
chr4_-_120595218 0.875


chr2_+_10101822 0.854 NM_001177718
KLF11
Kruppel-like factor 11
chr8_-_17148637 0.816 NM_013354
NM_054026
CNOT7

CCR4-NOT transcription complex, subunit 7

chr8_+_17148755 0.803 NM_001145152
NM_152415
VPS37A

vacuolar protein sorting 37 homolog A (S. cerevisiae)

chr5_+_78567604 0.798 NM_152405
JMY
junction mediating and regulatory protein, p53 cofactor
chr7_+_5598964 0.794 FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr19_+_523568 0.789 BSG
basigin (Ok blood group)
chr16_-_14631482 0.786 PARN
poly(A)-specific ribonuclease (deadenylation nuclease)
chr5_+_56505608 0.781 GPBP1
GC-rich promoter binding protein 1
chr19_+_18529652 0.763 C19orf50
chromosome 19 open reading frame 50
chr11_+_18372682 0.757 LDHA
lactate dehydrogenase A
chr20_+_1254033 0.755 LOC100507495
hypothetical LOC100507495
chr1_-_148079357 0.754 NM_021059
NM_001005464
HIST2H3C
HIST2H3A
histone cluster 2, H3c
histone cluster 2, H3a
chr7_-_129379947 0.746 NM_003344
NM_182697
UBE2H

ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)

chr11_+_18372689 0.743 LDHA
lactate dehydrogenase A
chr1_+_51855343 0.741 OSBPL9
oxysterol binding protein-like 9
chr16_-_14631595 0.741 NM_001134477
NM_002582
PARN

poly(A)-specific ribonuclease (deadenylation nuclease)

chr11_+_799918 0.740 NM_001004
RPLP2
ribosomal protein, large, P2
chr11_+_18372687 0.739 LDHA
lactate dehydrogenase A
chr20_-_33329319 0.732 EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr1_-_17318452 0.732 NM_007365
PADI2
peptidyl arginine deiminase, type II
chr16_+_2503994 0.729 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr1_+_9522133 0.724 SLC25A33
solute carrier family 25, member 33
chr7_+_5598979 0.719 NM_003088
FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr1_+_55277795 0.719 PCSK9
proprotein convertase subtilisin/kexin type 9
chr2_+_170149092 0.716 NM_004792
PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr11_+_18372708 0.712 LDHA
lactate dehydrogenase A
chr19_+_54067450 0.708 NM_014330
PPP1R15A
protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr3_+_38182251 0.706 OXSR1
oxidative-stress responsive 1
chr20_+_48240772 0.703 NM_005194
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr20_+_48240867 0.697 CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr20_+_48240705 0.696 CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr19_+_54067489 0.689 PPP1R15A
protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr19_+_40183065 0.686 NM_001136199
NM_020895
GRAMD1A

GRAM domain containing 1A

chr20_+_19863716 0.682 RIN2
Ras and Rab interactor 2
chr20_+_34635362 0.681 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr6_+_44463265 0.678 NM_001253
CDC5L
CDC5 cell division cycle 5-like (S. pombe)
chr11_+_799985 0.678 RPLP2
ribosomal protein, large, P2
chr20_+_57199469 0.676 NM_178457
ZNF831
zinc finger protein 831
chr12_+_22669352 0.676 ETNK1
ethanolamine kinase 1
chr19_+_523575 0.672 BSG
basigin (Ok blood group)
chr1_+_173235193 0.672 NM_001007214
CACYBP
calcyclin binding protein
chr5_+_112877251 0.670 NM_022828
YTHDC2
YTH domain containing 2
chr19_+_54067491 0.670 PPP1R15A
protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr20_+_30161173 0.668 TM9SF4
transmembrane 9 superfamily protein member 4
chr19_+_523403 0.667 NM_001728
NM_198589
BSG

basigin (Ok blood group)

chr12_+_22669275 0.664 NM_001039481
NM_018638
ETNK1

ethanolamine kinase 1

chr10_+_71833866 0.663 NM_004096
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr16_-_85146181 0.654 NM_001159380
NM_001159377
NM_001159378
NM_001159379
NM_022764
MTHFSD




methenyltetrahydrofolate synthetase domain containing




chr7_+_140042932 0.653 NM_004546
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr8_-_17148474 0.652 CNOT7
CCR4-NOT transcription complex, subunit 7
chr6_+_64339869 0.651 NM_003463
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr8_-_142446546 0.644 NM_005293
GPR20
G protein-coupled receptor 20
chr17_+_24095135 0.642 NM_004295
TRAF4
TNF receptor-associated factor 4
chr8_+_98856984 0.637 NM_018407
LAPTM4B
lysosomal protein transmembrane 4 beta
chr3_+_38182120 0.634 OXSR1
oxidative-stress responsive 1
chr10_+_71833905 0.630 EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr16_-_78192111 0.626 NM_001031804
NM_005360
MAF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

chr16_+_79906084 0.625 GAN
gigaxonin
chr19_+_54682661 0.622 RPL13A
ribosomal protein L13a
chr2_+_10969513 0.619 NM_002236
KCNF1
potassium voltage-gated channel, subfamily F, member 1
chr20_+_43996717 0.619 NM_022104
PCIF1
PDX1 C-terminal inhibiting factor 1
chr19_+_54682676 0.614 NM_012423
RPL13A
ribosomal protein L13a
chr8_-_95343696 0.608 GEM
GTP binding protein overexpressed in skeletal muscle
chr20_-_34635091 0.607


chr12_+_70119785 0.602 LGR5
leucine-rich repeat containing G protein-coupled receptor 5
chr11_+_18372493 0.602 NM_001135239
NM_001165415
NM_001165416
NM_005566
LDHA



lactate dehydrogenase A



chr8_-_95343716 0.600 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr16_+_3273369 0.596 NM_005741
ZNF263
zinc finger protein 263
chr19_+_40183169 0.593 GRAMD1A
GRAM domain containing 1A
chr16_+_79906065 0.593 NM_022041
GAN
gigaxonin
chr16_-_4837266 0.592 NM_032569
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr8_+_26204960 0.591 PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr16_+_29984591 0.581 ALDOA
aldolase A, fructose-bisphosphate
chr16_+_29984544 0.580 NM_184041
ALDOA
aldolase A, fructose-bisphosphate
chr1_+_114273518 0.579 NM_152696
NM_198268
HIPK1

homeodomain interacting protein kinase 1

chr17_+_22645268 0.577 WSB1
WD repeat and SOCS box containing 1
chr9_-_130683997 0.574 NM_001122671
NM_001122672
NM_004059
CCBL1


cysteine conjugate-beta lyase, cytoplasmic


chr17_-_76064842 0.568 NM_002522
NPTX1
neuronal pentraxin I
chr20_-_60151835 0.567 NM_002792
PSMA7
proteasome (prosome, macropain) subunit, alpha type, 7
chr2_+_170149348 0.567 PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr18_+_31963851 0.564 ELP2
elongation protein 2 homolog (S. cerevisiae)
chr16_+_29819647 0.564 NM_181718
ASPHD1
aspartate beta-hydroxylase domain containing 1
chr1_+_26368969 0.562 NM_015871
ZNF593
zinc finger protein 593
chr7_+_116447499 0.560 ST7
suppression of tumorigenicity 7
chr16_+_29984611 0.559 ALDOA
aldolase A, fructose-bisphosphate
chr9_+_130684189 0.559 NM_001127245
NM_019594
LRRC8A

leucine rich repeat containing 8 family, member A

chr14_+_54588151 0.558 MAPK1IP1L
mitogen-activated protein kinase 1 interacting protein 1-like
chr4_+_8493396 0.554 NM_152544
METTL19
methyltransferase like 19
chr6_-_3102690 0.553 NM_001069
TUBB2A
tubulin, beta 2A
chr8_+_26204921 0.545 NM_002717
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr18_+_31963879 0.542 NM_018255
ELP2
elongation protein 2 homolog (S. cerevisiae)
chr17_+_22645232 0.541 NM_015626
NM_134265
WSB1

WD repeat and SOCS box containing 1

chr16_+_54782802 0.538 GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr14_+_54588138 0.536 MAPK1IP1L
mitogen-activated protein kinase 1 interacting protein 1-like
chr6_+_64340408 0.527 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr9_+_130684248 0.525 LRRC8A
leucine rich repeat containing 8 family, member A
chr6_+_44463418 0.524 CDC5L
CDC5 cell division cycle 5-like (S. pombe)
chr1_+_6562681 0.522 ZBTB48
zinc finger and BTB domain containing 48
chr1_+_51474531 0.521 NM_014372
RNF11
ring finger protein 11
chr19_+_12917607 0.519 NM_005053
RAD23A
RAD23 homolog A (S. cerevisiae)
chr1_+_6562634 0.514 NM_005341
ZBTB48
zinc finger and BTB domain containing 48
chr16_+_29984647 0.511 ALDOA
aldolase A, fructose-bisphosphate
chr16_+_29984621 0.509 ALDOA
aldolase A, fructose-bisphosphate
chr7_-_127833231 0.509 NM_001142573
NM_001142574
NM_001142575
IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chr3_-_16281287 0.509 NM_001047434
NM_206831
DPH3

DPH3, KTI11 homolog (S. cerevisiae)

chr11_-_799465 0.509 LRDD
leucine-rich repeats and death domain containing
chr6_+_150112537 0.507 PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr7_+_107318852 0.507 DLD
dihydrolipoamide dehydrogenase
chr5_+_44844724 0.506 NM_016640
MRPS30
mitochondrial ribosomal protein S30
chr20_-_17897384 0.500 NM_152227
SNX5
sorting nexin 5
chr7_+_107318854 0.499 DLD
dihydrolipoamide dehydrogenase
chr6_-_43585958 0.499 C6orf154
chromosome 6 open reading frame 154
chr19_+_18529571 0.498 NM_001171948
NM_001171949
NM_024069
C19orf50


chromosome 19 open reading frame 50


chr19_-_10625449 0.497 LOC147727
hypothetical LOC147727
chr19_+_4353658 0.497 NM_005483
CHAF1A
chromatin assembly factor 1, subunit A (p150)
chr16_+_3273522 0.491 ZNF263
zinc finger protein 263
chr11_-_66367279 0.489


chr8_+_17824631 0.487 NM_006197
PCM1
pericentriolar material 1
chr17_+_45401560 0.486 NM_138281
DLX4
distal-less homeobox 4
chr20_+_17897529 0.484 NM_052865
C20orf72
chromosome 20 open reading frame 72
chrX_+_67635593 0.483 YIPF6
Yip1 domain family, member 6
chr8_-_11361594 0.481 NM_053279
FAM167A
family with sequence similarity 167, member A
chr19_-_8670054 0.481 NM_178525
ACTL9
actin-like 9
chr3_+_129690735 0.481


chr1_-_20916789 0.479 NM_001122819
NM_020816
KIF17

kinesin family member 17

chr3_+_125931962 0.478 UMPS
uridine monophosphate synthetase
chr1_+_11962824 0.478 NM_001127660
NM_014874
MFN2

mitofusin 2

chr17_+_45221002 0.476 MYST2
MYST histone acetyltransferase 2
chr20_+_33823318 0.473 NM_016436
PHF20
PHD finger protein 20
chr6_-_15356865 0.473


chr7_+_107318821 0.472 NM_000108
DLD
dihydrolipoamide dehydrogenase
chr20_-_60151802 0.470 PSMA7
proteasome (prosome, macropain) subunit, alpha type, 7
chr20_+_25124333 0.463 NM_001114089
NM_001247
ENTPD6

ectonucleoside triphosphate diphosphohydrolase 6 (putative)

chr14_+_23968979 0.461 NM_015299
KHNYN
KH and NYN domain containing
chr2_-_156897286 0.460 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr2_+_107809819 0.460 NM_182588
RGPD4
RANBP2-like and GRIP domain containing 4
chr1_+_149520601 0.459 ZNF687
zinc finger protein 687
chr4_+_109130491 0.458 HADH
hydroxyacyl-CoA dehydrogenase
chr14_+_54588125 0.458 MAPK1IP1L
mitogen-activated protein kinase 1 interacting protein 1-like
chr19_-_17047228 0.458 NM_001011699
NM_033417
HAUS8

HAUS augmin-like complex, subunit 8

chr6_+_64340388 0.455 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr2_+_60962279 0.454 REL
v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr6_-_34963565 0.451 NM_005643
TAF11
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
chr19_-_54231884 0.449 NM_033377
CGB1
CGB2
chorionic gonadotropin, beta polypeptide 1
chorionic gonadotropin, beta polypeptide 2
chr3_+_185536376 0.449 NM_001171093
FAM131A
family with sequence similarity 131, member A
chr4_+_1842947 0.448 WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr21_-_43903755 0.447 NM_007031
HSF2BP
heat shock transcription factor 2 binding protein
chr1_+_1994943 0.446 NM_001033581
PRKCZ
protein kinase C, zeta
chr7_+_152087753 0.446 NM_001040135
NM_020445
ACTR3B

ARP3 actin-related protein 3 homolog B (yeast)

chr8_+_17824772 0.446 PCM1
pericentriolar material 1
chr19_+_47080285 0.445 NM_199002
ARHGEF1
Rho guanine nucleotide exchange factor (GEF) 1
chr8_+_17824781 0.443 PCM1
pericentriolar material 1
chr19_+_12917656 0.443 RAD23A
RAD23 homolog A (S. cerevisiae)
chr18_+_18767275 0.442 NM_002894
RBBP8
retinoblastoma binding protein 8
chr3_+_125931902 0.441 NM_000373
UMPS
uridine monophosphate synthetase
chr1_+_55277736 0.441 NM_174936
PCSK9
proprotein convertase subtilisin/kexin type 9
chr19_+_54872220 0.440 PRMT1
protein arginine methyltransferase 1
chr6_+_30137014 0.440 NM_014596
NM_170783
ZNRD1

zinc ribbon domain containing 1

chr6_-_30631912 0.439 GNL1
guanine nucleotide binding protein-like 1
chr6_+_31016755 0.439 NM_080870
DPCR1
diffuse panbronchiolitis critical region 1
chr6_-_31882558 0.436 LSM2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr8_+_17824790 0.435 PCM1
pericentriolar material 1
chr19_+_16048047 0.432 NM_003290
TPM4
tropomyosin 4
chr17_+_45221060 0.432 NM_007067
MYST2
MYST histone acetyltransferase 2
chr2_+_131579334 0.431 PLEKHB2
pleckstrin homology domain containing, family B (evectins) member 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.54 8.12e-10 GO:0034641 cellular nitrogen compound metabolic process
1.60 9.14e-10 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.33 1.99e-09 GO:0044237 cellular metabolic process
1.52 3.19e-09 GO:0006807 nitrogen compound metabolic process
1.42 4.79e-09 GO:0044260 cellular macromolecule metabolic process
1.38 5.07e-09 GO:0043170 macromolecule metabolic process
1.28 1.48e-08 GO:0008152 metabolic process
1.31 1.62e-08 GO:0044238 primary metabolic process
1.16 6.62e-08 GO:0009987 cellular process
1.57 1.79e-06 GO:0090304 nucleic acid metabolic process
1.58 4.32e-05 GO:0010467 gene expression
1.52 2.11e-03 GO:0016070 RNA metabolic process
1.41 3.16e-03 GO:0044249 cellular biosynthetic process
1.63 3.99e-03 GO:0044248 cellular catabolic process
1.51 4.50e-03 GO:0034645 cellular macromolecule biosynthetic process
1.50 4.92e-03 GO:0009059 macromolecule biosynthetic process
1.51 6.70e-03 GO:0006996 organelle organization
1.31 1.04e-02 GO:0071840 cellular component organization or biogenesis
1.38 1.19e-02 GO:0009058 biosynthetic process
1.84 1.50e-02 GO:0051276 chromosome organization
1.52 1.68e-02 GO:0009056 catabolic process
18.51 1.68e-02 GO:0070584 mitochondrion morphogenesis
1.97 1.85e-02 GO:0006325 chromatin organization
2.16 2.37e-02 GO:0009259 ribonucleotide metabolic process
2.17 2.62e-02 GO:0009150 purine ribonucleotide metabolic process
2.84 2.85e-02 GO:0006333 chromatin assembly or disassembly
2.98 3.54e-02 GO:0050657 nucleic acid transport
2.98 3.54e-02 GO:0050658 RNA transport
2.98 3.54e-02 GO:0051236 establishment of RNA localization
1.98 3.89e-02 GO:0072521 purine-containing compound metabolic process
1.29 4.57e-02 GO:0016043 cellular component organization
1.88 4.57e-02 GO:0006753 nucleoside phosphate metabolic process
1.88 4.57e-02 GO:0009117 nucleotide metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.26 1.56e-13 GO:0043231 intracellular membrane-bounded organelle
1.26 2.05e-13 GO:0043227 membrane-bounded organelle
1.19 2.21e-13 GO:0044424 intracellular part
1.18 1.08e-12 GO:0005622 intracellular
1.39 2.42e-12 GO:0044446 intracellular organelle part
1.38 5.18e-12 GO:0044422 organelle part
1.21 4.31e-11 GO:0043229 intracellular organelle
1.69 5.56e-11 GO:0044428 nuclear part
1.21 6.65e-11 GO:0043226 organelle
1.73 7.26e-10 GO:0031981 nuclear lumen
1.64 8.55e-10 GO:0070013 intracellular organelle lumen
1.62 2.68e-09 GO:0043233 organelle lumen
1.61 3.29e-09 GO:0031974 membrane-enclosed lumen
1.33 1.17e-08 GO:0005634 nucleus
1.70 5.59e-06 GO:0005654 nucleoplasm
1.17 1.56e-04 GO:0005737 cytoplasm
1.96 4.02e-04 GO:0005694 chromosome
1.97 1.09e-03 GO:0005730 nucleolus
1.96 2.93e-03 GO:0044427 chromosomal part
1.33 6.21e-03 GO:0043228 non-membrane-bounded organelle
1.33 6.21e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.19 6.81e-03 GO:0044444 cytoplasmic part
1.36 2.44e-02 GO:0031090 organelle membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.28 6.23e-10 GO:0005515 protein binding
1.15 4.61e-09 GO:0005488 binding
1.54 3.76e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.47 5.15e-05 GO:0000166 nucleotide binding
1.51 1.03e-04 GO:0032553 ribonucleotide binding
1.51 1.03e-04 GO:0032555 purine ribonucleotide binding
1.50 1.44e-04 GO:0017076 purine nucleotide binding
1.83 2.84e-04 GO:0017111 nucleoside-triphosphatase activity
1.79 5.57e-04 GO:0016462 pyrophosphatase activity
1.33 6.30e-04 GO:0003676 nucleic acid binding
1.78 6.46e-04 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.78 7.48e-04 GO:0016817 hydrolase activity, acting on acid anhydrides
1.23 1.60e-03 GO:0003824 catalytic activity
1.51 2.23e-03 GO:0005524 ATP binding
1.50 2.78e-03 GO:0032559 adenyl ribonucleotide binding
1.49 3.59e-03 GO:0030554 adenyl nucleotide binding
2.40 1.10e-02 GO:0003924 GTPase activity