Motif ID: BACH2.p2

Z-value: 1.687


Transcription factors associated with BACH2.p2:

Gene SymbolEntrez IDGene Name
BACH2 60468 BTB and CNC homology 1, basic leucine zipper transcription factor 2



Activity profile for motif BACH2.p2.

activity profile for motif BACH2.p2


Sorted Z-values histogram for motif BACH2.p2

Sorted Z-values for motif BACH2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of BACH2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_21370394 6.128 IGL@
immunoglobulin lambda locus
chr22_+_21495273 5.383


chr22_+_21340757 3.829


chr7_-_158304062 2.966 ESYT2
extended synaptotagmin-like protein 2
chr22_+_20715340 2.853


chr7_+_150319076 2.752 NM_000603
NOS3
nitric oxide synthase 3 (endothelial cell)
chr22_+_21552897 2.736 LOC100290481
immunoglobulin lambda light chain-like
chr17_-_37022465 2.733 NM_005557
KRT16
keratin 16
chr10_+_134751398 2.600 NM_001083909
GPR123
G protein-coupled receptor 123
chr22_+_21079355 2.563


chr22_+_21464980 2.543


chr3_-_188936941 2.502 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr20_-_51633042 2.446 NM_006526
ZNF217
zinc finger protein 217
chr22_+_21393107 2.415 IGLJ3
immunoglobulin lambda joining 3
chr1_-_6474346 2.319 NM_020631
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr16_+_87765661 2.173 NM_004933
CDH15
cadherin 15, type 1, M-cadherin (myotubule)
chr7_+_1543644 2.116 MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr22_+_19191884 1.921 NM_001003891
NM_015889
MED15

mediator complex subunit 15

chr17_+_72883759 1.921 NM_001113494
SEPT9
septin 9
chr22_+_21116283 1.896


chr22_+_19191875 1.849 MED15
mediator complex subunit 15
chr22_+_21053972 1.841


chr8_-_143848225 1.836 NM_177458
LYNX1
Ly6/neurotoxin 1
chr22_+_19191886 1.830 MED15
mediator complex subunit 15
chr22_+_19191898 1.824 MED15
mediator complex subunit 15
chr10_+_70745615 1.802 NM_033496
HK1
hexokinase 1
chr22_+_21006814 1.776


chr22_+_19191859 1.769 MED15
mediator complex subunit 15
chr22_+_19191964 1.745 MED15
mediator complex subunit 15
chr7_+_30927439 1.713 NM_001185060
NM_001185061
NM_001185062
AQP1


aquaporin 1 (Colton blood group)


chr16_+_29984647 1.697 ALDOA
aldolase A, fructose-bisphosphate
chr16_+_82544327 1.696 NM_182981
OSGIN1
oxidative stress induced growth inhibitor 1
chr6_-_41781655 1.675 TFEB
transcription factor EB
chr16_+_1230678 1.670 NM_003294
TPSB2
TPSAB1
tryptase beta 2 (gene/pseudogene)
tryptase alpha/beta 1
chr16_+_29984611 1.664 ALDOA
aldolase A, fructose-bisphosphate
chr3_-_195571748 1.658 NM_001135057
NM_130830
LRRC15

leucine rich repeat containing 15

chr16_+_29984621 1.634 ALDOA
aldolase A, fructose-bisphosphate
chr1_+_17719405 1.612 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr2_+_87536106 1.611 NCRNA00152
non-protein coding RNA 152
chr12_+_50981915 1.603 NM_002284
KRT86
keratin 86
chr22_+_21042091 1.547 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr2_+_87536174 1.533 NCRNA00152
non-protein coding RNA 152
chr16_+_29984591 1.504 ALDOA
aldolase A, fructose-bisphosphate
chr9_+_137694988 1.471 NM_001001676
LCN9
lipocalin 9
chr8_+_22900863 1.462 NM_001160036
RHOBTB2
Rho-related BTB domain containing 2
chr16_+_29984544 1.441 NM_184041
ALDOA
aldolase A, fructose-bisphosphate
chr13_+_112746908 1.417 MCF2L
MCF.2 cell line derived transforming sequence-like
chr1_-_36589744 1.384


chr9_+_131291144 1.342


chr6_+_107066422 1.319 NM_001624
AIM1
absent in melanoma 1
chr3_-_48607596 1.301 NM_000094
COL7A1
collagen, type VII, alpha 1
chr8_-_103735194 1.289 NM_001032282
KLF10
Kruppel-like factor 10
chr9_+_139255559 1.280 TUBB2C
tubulin, beta 2C
chr9_+_131291224 1.246 LOC100506190
hypothetical LOC100506190
chr16_+_88515917 1.231 NM_001197181
TUBB3
tubulin, beta 3
chr15_-_97607108 1.204 NM_001040655
NM_001040656
NM_001040657
NM_001040658
NM_001040659
NM_001040660
NM_022905
TTC23






tetratricopeptide repeat domain 23






chr19_+_54068300 1.180 PPP1R15A
protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr9_+_137593420 1.176 NM_001018049
NM_002571
PAEP

progestagen-associated endometrial protein

chr6_-_31853027 1.156 NM_025258
C6orf27
chromosome 6 open reading frame 27
chr7_+_149696263 1.154 REPIN1
replication initiator 1
chr1_-_45045543 1.147 NM_001013632
TCTEX1D4
Tctex1 domain containing 4
chr17_+_22823151 1.144 NM_014238
KSR1
kinase suppressor of ras 1
chr6_+_31190505 1.143 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr17_+_72827227 1.133 SEPT9
septin 9
chr16_-_1086244 1.120 NM_207419
C1QTNF8
C1q and tumor necrosis factor related protein 8
chr22_+_21011653 1.105


chr11_-_8695974 1.093 ST5
suppression of tumorigenicity 5
chr22_+_21065207 1.081 IGLJ3
immunoglobulin lambda joining 3
chr16_+_2023279 1.078 SLC9A3R2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr1_+_20338405 1.077 NM_022819
PLA2G2F
phospholipase A2, group IIF
chr21_+_39951123 1.057 NM_006057
NM_033170
NM_033171
NM_033172
NM_033173
B3GALT5




UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5




chr19_-_56215084 1.056 NM_002776
NM_001077500
KLK10

kallikrein-related peptidase 10

chr22_+_21065202 1.052


chr21_+_31953803 1.043 NM_000454
SOD1
superoxide dismutase 1, soluble
chr19_-_40711034 1.042 NM_001166034
NM_001166035
NM_198538
SBSN


suprabasin


chr6_-_149847718 1.037 ZC3H12D
zinc finger CCCH-type containing 12D
chr20_+_42463387 1.035 HNF4A
hepatocyte nuclear factor 4, alpha
chr19_+_55164668 1.033 SIGLEC16
sialic acid binding Ig-like lectin 16 (gene/pseudogene)
chr11_+_10433241 1.033 NM_001025389
AMPD3
adenosine monophosphate deaminase 3
chr22_+_21065134 1.023 LOC100290481
immunoglobulin lambda light chain-like
chr19_-_3920736 1.022 NM_001348
DAPK3
death-associated protein kinase 3
chr4_-_100575313 1.003 NM_001166504
NM_000673
ADH7

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

chr22_+_20899155 0.985


chr7_-_33047042 0.983 NM_001166118
NM_016489
NT5C3

5'-nucleotidase, cytosolic III

chr20_+_42463350 0.958 HNF4A
hepatocyte nuclear factor 4, alpha
chr1_-_177378801 0.928 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr20_+_42463419 0.926 HNF4A
hepatocyte nuclear factor 4, alpha
chr5_+_176170041 0.926 NM_133369
UNC5A
unc-5 homolog A (C. elegans)
chr14_-_100105883 0.925 NM_020836
BEGAIN
brain-enriched guanylate kinase-associated homolog (rat)
chr19_+_54068373 0.925 PPP1R15A
protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr11_-_2907169 0.925 NM_003311
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr7_+_133884388 0.921 NM_001080538
AKR1B15
aldo-keto reductase family 1, member B15
chr17_+_72827185 0.917 NM_006640
SEPT9
septin 9
chr19_+_7859380 0.914 NM_025061
LRRC8E
leucine rich repeat containing 8 family, member E
chr6_-_149847809 0.907 NM_207360
ZC3H12D
zinc finger CCCH-type containing 12D
chr8_+_26206648 0.898 NM_001177591
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr11_-_6298284 0.874 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr7_+_150065594 0.874 GIMAP5
GTPase, IMAP family member 5
chr9_+_139255563 0.870 TUBB2C
tubulin, beta 2C
chr20_+_42463279 0.867 NM_000457
NM_178849
NM_178850
HNF4A


hepatocyte nuclear factor 4, alpha


chr6_-_30793436 0.861 NM_014641
MDC1
mediator of DNA-damage checkpoint 1
chr22_-_28972683 0.842 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr2_+_119905812 0.841 NM_183240
TMEM37
transmembrane protein 37
chr16_+_56219802 0.837 NM_001145771
NM_001145772
NM_001145773
NM_201524
NM_201525
GPR56




G protein-coupled receptor 56




chr11_+_12265022 0.834 NM_032867
MICALCL
MICAL C-terminal like
chr8_-_38505331 0.830 NM_207412
C8orf86
chromosome 8 open reading frame 86
chr3_-_11585264 0.828 NM_001128221
VGLL4
vestigial like 4 (Drosophila)
chr11_-_65860450 0.826 NM_004292
RIN1
Ras and Rab interactor 1
chr1_+_3378030 0.826 ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr1_-_232810478 0.824


chr6_+_47774247 0.802 NM_153838
GPR115
G protein-coupled receptor 115
chr1_-_1679940 0.798 NM_001198995
NADK
NAD kinase
chr11_+_18372493 0.790 NM_001135239
NM_001165415
NM_001165416
NM_005566
LDHA



lactate dehydrogenase A



chr6_+_41712907 0.787 MDFI
MyoD family inhibitor
chr1_+_891739 0.786 NM_001160184
NM_032129
PLEKHN1

pleckstrin homology domain containing, family N member 1

chr1_+_19511326 0.771 NM_001040125
NM_001040126
NM_017765
PQLC2


PQ loop repeat containing 2


chr1_+_151456683 0.765 NM_001195571
PRR9
proline rich 9
chr1_+_111818111 0.765 NM_174896
C1orf162
chromosome 1 open reading frame 162
chr1_+_148747110 0.763 NM_004425
NM_022664
ECM1

extracellular matrix protein 1

chr19_+_2187815 0.761 NM_007165
SF3A2
splicing factor 3a, subunit 2, 66kDa
chr1_-_232810111 0.756 IRF2BP2
interferon regulatory factor 2 binding protein 2
chr1_+_15128882 0.753 NM_001018001
KAZN
kazrin, periplakin interacting protein
chr19_-_40673185 0.747 NM_207392
KRTDAP
keratinocyte differentiation-associated protein
chr1_+_54780515 0.746 ACOT11
acyl-CoA thioesterase 11
chr22_-_43040063 0.741 NM_001099294
KIAA1644
KIAA1644
chr3_+_38363292 0.741 XYLB
xylulokinase homolog (H. influenzae)
chr1_-_207891264 0.736 NM_001017402
LAMB3
laminin, beta 3
chr7_-_38355949 0.724


chr7_+_72883128 0.722 NM_001305
CLDN4
claudin 4
chr3_+_38363299 0.721 XYLB
xylulokinase homolog (H. influenzae)
chr1_+_153232685 0.721 NM_018655
LENEP
lens epithelial protein
chr17_-_36996611 0.720 NM_000526
KRT14
keratin 14
chr21_+_46367216 0.709 COL6A2
collagen, type VI, alpha 2
chr16_+_4370879 0.705 VASN
vasorin
chr17_-_53335748 0.702 NM_017949
CUEDC1
CUE domain containing 1
chr9_+_139255519 0.701 NM_006088
TUBB2C
tubulin, beta 2C
chr1_-_153209625 0.700 NM_001130040
NM_183001
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chr16_+_51690564 0.699 CHD9
chromodomain helicase DNA binding protein 9
chr8_+_105421226 0.699 NM_030788
TM7SF4
transmembrane 7 superfamily member 4
chr17_-_24491521 0.697 MYO18A
myosin XVIIIA
chr22_+_21027538 0.697


chr10_-_44775110 0.689 LOC220980
hypothetical LOC220980
chr1_+_17738863 0.689 NM_018125
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr11_+_1812115 0.687 NM_138567
SYT8
synaptotagmin VIII
chr6_+_33151703 0.676 NM_002121
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr3_+_38363226 0.665 NM_005108
XYLB
xylulokinase homolog (H. influenzae)
chr7_-_135083906 0.663 NM_205855
FAM180A
family with sequence similarity 180, member A
chr2_-_65447267 0.653 SPRED2
sprouty-related, EVH1 domain containing 2
chr4_+_88076418 0.651


chr20_+_44070946 0.651 NM_004994
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chrX_+_30143595 0.648 NM_002364
MAGEB2
melanoma antigen family B, 2
chr1_-_232810443 0.646


chr19_+_43486640 0.645 NM_033520
C19orf33
chromosome 19 open reading frame 33
chr5_-_158690047 0.644 NM_002187
IL12B
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
chr5_+_40877053 0.642 NM_032587
CARD6
caspase recruitment domain family, member 6
chr22_+_19699441 0.632 NM_001159554
NM_005446
P2RX6

purinergic receptor P2X, ligand-gated ion channel, 6

chr17_-_24069299 0.625 NM_001142624
NM_001142625
NM_001144943
RAB34


RAB34, member RAS oncogene family


chr19_+_55398680 0.623 NM_001077186
NM_001145809
NM_024729
MYH14


myosin, heavy chain 14, non-muscle


chr16_+_29697090 0.619 ZG16
zymogen granule protein 16 homolog (rat)
chr21_+_29439768 0.616 C21orf7
chromosome 21 open reading frame 7
chr19_+_59107802 0.612 NM_031896
CACNG7
calcium channel, voltage-dependent, gamma subunit 7
chr7_-_7724762 0.609 NM_002947
RPA3
replication protein A3, 14kDa
chr10_-_44775142 0.609 LOC220980
hypothetical LOC220980
chr7_+_1092968 0.608 NM_001039966
NM_001505
GPER

G protein-coupled estrogen receptor 1

chr2_-_65447370 0.607 NM_001128210
SPRED2
sprouty-related, EVH1 domain containing 2
chr16_+_31274030 0.605 ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr16_+_73810383 0.604 NM_001906
CTRB1
CTRB2
chymotrypsinogen B1
chymotrypsinogen B2
chr9_+_126253243 0.592 NM_001161808
GPR144
G protein-coupled receptor 144
chr3_+_64645819 0.591 LOC100507098
hypothetical LOC100507098
chr19_+_45564549 0.586 PLD3
phospholipase D family, member 3
chr14_-_93924663 0.586 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr7_+_102078007 0.585 NM_001166339
NM_001031618
SPDYE2L
SPDYE2
WBSCR19-like protein 3
speedy homolog E2 (Xenopus laevis)
chr16_+_1246273 0.585 NM_012217
TPSD1
tryptase delta 1
chr1_-_17180659 0.584 NM_001135247
NM_017459
MFAP2

microfibrillar-associated protein 2

chr8_-_42742729 0.580 NM_004198
CHRNA6
cholinergic receptor, nicotinic, alpha 6
chr12_+_54760153 0.579 NM_001005915
NM_001982
ERBB3

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

chr1_+_27591738 0.564 NM_005281
GPR3
G protein-coupled receptor 3
chr6_+_44302973 0.563 SLC29A1
solute carrier family 29 (nucleoside transporters), member 1
chr16_+_31312097 0.562 NM_005353
ITGAD
integrin, alpha D
chr7_-_150352484 0.562 NM_173681
ATG9B
ATG9 autophagy related 9 homolog B (S. cerevisiae)
chr6_+_30983941 0.559 NM_001517
GTF2H4
general transcription factor IIH, polypeptide 4, 52kDa
chr22_-_41672990 0.558 NM_007229
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr17_+_72958207 0.551 NM_001113496
SEPT9
septin 9
chr17_+_27701291 0.551 ZNF207
zinc finger protein 207
chrX_-_48654178 0.550 NM_001042498
SLC35A2
solute carrier family 35 (UDP-galactose transporter), member A2
chr16_-_1220163 0.546 NM_024164
TPSB2
TPSAB1
tryptase beta 2 (gene/pseudogene)
tryptase alpha/beta 1
chr7_+_99865189 0.541 NM_019606
MEPCE
methylphosphate capping enzyme
chr1_-_154941861 0.536 NM_001878
CRABP2
cellular retinoic acid binding protein 2
chr11_+_113351006 0.529 NM_000869
NM_213621
HTR3A

5-hydroxytryptamine (serotonin) receptor 3A

chr3_-_152517204 0.527 NM_023915
GPR87
G protein-coupled receptor 87
chr6_-_150388292 0.526 NM_130900
RAET1L
retinoic acid early transcript 1L
chr7_+_128219307 0.520 NM_022742
CCDC136
coiled-coil domain containing 136
chr19_-_13121986 0.519 NM_003765
STX10
syntaxin 10
chr19_-_2187648 0.518 PLEKHJ1
pleckstrin homology domain containing, family J member 1
chr1_+_201363458 0.517 NM_000674
NM_001048230
ADORA1

adenosine A1 receptor

chr21_+_29593098 0.516 BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr6_-_28429950 0.516 NM_145909
ZNF323
zinc finger protein 323
chr4_+_170817787 0.510 CLCN3
chloride channel 3
chr17_-_24068759 0.508 NM_001144942
NM_031934
RAB34

RAB34, member RAS oncogene family

chr22_+_21094094 0.506



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.88 5.89e-04 GO:0042981 regulation of apoptosis
1.86 8.10e-04 GO:0043067 regulation of programmed cell death
1.83 1.45e-03 GO:0010941 regulation of cell death

Nothing significant found in compartment category.

Nothing significant found in function category.