Motif ID: CDC5L.p2

Z-value: 2.230


Transcription factors associated with CDC5L.p2:

Gene SymbolEntrez IDGene Name
CDC5L 988 CDC5 cell division cycle 5-like (S. pombe)



Activity profile for motif CDC5L.p2.

activity profile for motif CDC5L.p2


Sorted Z-values histogram for motif CDC5L.p2

Sorted Z-values for motif CDC5L.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CDC5L.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_29882555 4.650 NM_001198549
NOL4
nucleolar protein 4
chr12_-_78831821 3.995 NM_001143886
PPP1R12A
protein phosphatase 1, regulatory (inhibitor) subunit 12A
chr11_+_101488380 3.501 NM_001195045
YAP1
Yes-associated protein 1
chr4_-_149577404 3.444


chr12_+_54080480 3.401 NM_001005518
OR6C65
olfactory receptor, family 6, subfamily C, member 65
chr20_-_33706532 3.350 RBM12
RNA binding motif protein 12
chr11_-_83706027 3.082 DLG2
discs, large homolog 2 (Drosophila)
chr2_+_183316574 3.049 DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr5_-_138238877 3.009 LRRTM2
leucine rich repeat transmembrane neuronal 2
chr9_-_13240313 2.934 NM_003829
MPDZ
multiple PDZ domain protein
chr14_+_28311740 2.845 C14orf23
chromosome 14 open reading frame 23
chr7_-_122627235 2.806 NM_022444
SLC13A1
solute carrier family 13 (sodium/sulfate symporters), member 1
chr5_-_138238891 2.794 CTNNA1
LRRTM2
catenin (cadherin-associated protein), alpha 1, 102kDa
leucine rich repeat transmembrane neuronal 2
chr12_+_77963563 2.782 NM_001135806
SYT1
synaptotagmin I
chr15_+_47502666 2.773 NM_002009
FGF7
fibroblast growth factor 7
chr18_+_59593591 2.709 NM_003784
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr3_-_121117647 2.609 GSK3B
glycogen synthase kinase 3 beta
chr17_-_2943039 2.489 NM_002548
OR1D2
olfactory receptor, family 1, subfamily D, member 2
chr3_+_35696119 2.482 NM_001025068
NM_001025069
ARPP21

cAMP-regulated phosphoprotein, 21kDa

chr2_+_211166323 2.478 NM_001122634
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr5_+_147423727 2.471 NM_001127698
NM_001127699
NM_006846
SPINK5


serine peptidase inhibitor, Kazal type 5


chr11_+_27019084 2.449 NM_003986
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr6_+_64414389 2.416 NM_015153
PHF3
PHD finger protein 3
chr2_+_162189090 2.318 NM_001178015
NM_001178016
NM_022058
SLC4A10


solute carrier family 4, sodium bicarbonate transporter, member 10


chr2_-_210888010 2.304 NM_079420
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr20_-_33705244 2.260 NM_003915
CPNE1
copine I
chr2_-_215949566 2.206 FN1
fibronectin 1
chr10_-_27097782 2.199 ABI1
abl-interactor 1
chr11_-_13474101 2.181 NM_000315
PTH
parathyroid hormone
chr12_-_44877769 2.131 SLC38A1
solute carrier family 38, member 1
chr12_-_10433852 2.125 NM_007360
KLRK1
killer cell lectin-like receptor subfamily K, member 1
chr9_+_74956601 2.104 ANXA1
annexin A1
chr18_-_39111243 2.086 NM_020783
SYT4
synaptotagmin IV
chr18_-_35634247 2.078 LOC647946
hypothetical LOC647946
chr6_+_127940011 2.074 NM_001010905
C6orf58
chromosome 6 open reading frame 58
chr2_-_133895795 2.010 NCKAP5
NCK-associated protein 5
chr2_+_227900471 1.997 NM_020194
MFF
mitochondrial fission factor
chr9_+_74956614 1.990 ANXA1
annexin A1
chr11_-_6005546 1.984 NM_001001917
OR56A1
olfactory receptor, family 56, subfamily A, member 1
chr9_+_74956494 1.984 NM_000700
ANXA1
annexin A1
chr20_-_39362122 1.945 NM_015035
ZHX3
zinc fingers and homeoboxes 3
chr2_+_228386800 1.933 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr2_+_165804157 1.868 NM_001040142
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr8_+_75899326 1.865 NM_015886
PI15
peptidase inhibitor 15
chr2_+_214984705 1.860 NM_001080500
VWC2L
von Willebrand factor C domain containing protein 2-like
chr16_+_14201687 1.849 MKL2
MKL/myocardin-like 2
chr2_-_162717159 1.835 NM_002054
GCG
glucagon
chr5_-_138238953 1.811 NM_015564
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr16_+_68238460 1.773 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr3_+_73193499 1.749 NM_018029
EBLN2
endogenous Borna-like N element-2
chr17_-_36451189 1.696 NM_030967
KRTAP1-3
KRTAP1-1
keratin associated protein 1-3
keratin associated protein 1-1
chr9_-_106420305 1.687 NM_001001956
OR13C9
olfactory receptor, family 13, subfamily C, member 9
chr4_-_80548378 1.669 NM_033214
GK2
glycerol kinase 2
chr2_-_21106291 1.661 APOB
apolipoprotein B (including Ag(x) antigen)
chr6_+_55147029 1.642 NM_001526
HCRTR2
hypocretin (orexin) receptor 2
chr15_+_70193652 1.621 NM_001166340
SENP8
SUMO/sentrin specific peptidase family member 8
chr3_-_131081910 1.614 NM_001017395
TMCC1
transmembrane and coiled-coil domain family 1
chr1_-_196776697 1.604 NM_133262
NM_133326
ATP6V1G3

ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3

chr20_+_23293020 1.601 NM_022482
GZF1
GDNF-inducible zinc finger protein 1
chr12_-_44919818 1.559 SLC38A1
solute carrier family 38, member 1
chr12_+_21417068 1.539 NM_000415
IAPP
islet amyloid polypeptide
chr18_+_59705918 1.524 NM_001143818
NM_002575
SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr10_+_126620681 1.494 NM_017580
ZRANB1
zinc finger, RAN-binding domain containing 1
chr6_-_133008834 1.492 NM_138327
TAAR1
trace amine associated receptor 1
chr8_+_32623792 1.489 NM_013959
NRG1
neuregulin 1
chr2_+_100453375 1.473 NM_001011717
NMS
neuromedin S
chrX_-_83644054 1.473 NM_001177478
NM_001177479
NM_144657
HDX


highly divergent homeobox


chr4_+_95595419 1.469 PDLIM5
PDZ and LIM domain 5
chr8_+_104380234 1.461 NM_001164616
NM_003506
FZD6

frizzled homolog 6 (Drosophila)

chr6_-_90081655 1.458 NM_002043
GABRR2
gamma-aminobutyric acid (GABA) receptor, rho 2
chr15_+_100175888 1.455 NM_001001674
OR4F15
olfactory receptor, family 4, subfamily F, member 15
chr12_+_18305740 1.445 NM_004570
PIK3C2G
phosphoinositide-3-kinase, class 2, gamma polypeptide
chr21_-_30774502 1.440 NM_181607
KRTAP19-1
keratin associated protein 19-1
chr6_-_112001590 1.437 NM_001164282
TRAF3IP2
TRAF3 interacting protein 2
chr1_-_85816520 1.436 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr1_-_150328153 1.429 NM_001008536
TCHHL1
trichohyalin-like 1
chr10_+_96688399 1.423 NM_000771
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9
chr11_+_33319680 1.415 HIPK3
homeodomain interacting protein kinase 3
chr21_+_37714470 1.409 NM_130438
NM_001396
DYRK1A

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

chr11_-_100505667 1.404 NM_000926
PGR
progesterone receptor
chrX_-_15312390 1.396 NM_004469
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chr10_+_106003941 1.394 NM_001191003
GSTO1
glutathione S-transferase omega 1
chr14_-_94677807 1.387 NM_030621
DICER1
dicer 1, ribonuclease type III
chr12_-_9123126 1.375 A2M
alpha-2-macroglobulin
chr7_-_113346284 1.375 NM_002711
PPP1R3A
protein phosphatase 1, regulatory (inhibitor) subunit 3A
chr2_-_225078931 1.375 CUL3
cullin 3
chr13_-_40454360 1.370 NM_001145353
ELF1
E74-like factor 1 (ets domain transcription factor)
chr13_+_47948586 1.320 RB1
retinoblastoma 1
chr14_-_106193403 1.300 IGKV3-20
immunoglobulin kappa variable 3-20
chr7_+_80145461 1.249 CD36
CD36 molecule (thrombospondin receptor)
chr9_-_103185621 1.229 NM_001127610
BAAT
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr12_-_25041639 1.228 NM_001101339
C12orf77
chromosome 12 open reading frame 77
chr7_-_26202626 1.219 HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr9_+_104797413 1.216 NM_001340
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr1_+_63022359 1.214 NM_032852
NM_178221
ATG4C

ATG4 autophagy related 4 homolog C (S. cerevisiae)

chr5_+_147775652 1.208 FBXO38
F-box protein 38
chr18_-_49944986 1.206 MBD2
methyl-CpG binding domain protein 2
chr3_+_103636548 1.204 NM_175056
ZPLD1
zona pellucida-like domain containing 1
chr10_+_63478974 1.192 ARID5B
AT rich interactive domain 5B (MRF1-like)
chr4_+_119174947 1.185 NM_004784
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr4_+_74499651 1.180 ALB
albumin
chr3_+_99484421 1.172 NM_001005482
OR5H2
olfactory receptor, family 5, subfamily H, member 2
chr7_+_156716694 1.169


chr14_+_38772870 1.160 NM_054024
MIA2
melanoma inhibitory activity 2
chr9_-_21340885 1.153 NM_021002
IFNA6
interferon, alpha 6
chr6_+_57290357 1.142 NM_000947
PRIM2
primase, DNA, polypeptide 2 (58kDa)
chr13_-_85271329 1.136 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr13_+_77213295 1.120 NM_144595
SLAIN1
SLAIN motif family, member 1
chr20_-_13919256 1.109 NM_025229
SEL1L2
sel-1 suppressor of lin-12-like 2 (C. elegans)
chr8_-_9451439 1.100


chr1_-_58920315 1.056


chr2_-_37397669 1.054 NM_005813
PRKD3
protein kinase D3
chr11_+_33306652 1.048 HIPK3
homeodomain interacting protein kinase 3
chr2_-_197383120 1.043 NM_213608
C2orf66
chromosome 2 open reading frame 66
chr4_+_38740246 1.037 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr8_-_62764839 1.037 NM_001164750
NM_001164751
NM_001164752
NM_001164753
NM_020164
NM_032467
NM_032468
ASPH






aspartate beta-hydroxylase






chr14_+_69307914 1.030 SRSF5
serine/arginine-rich splicing factor 5
chr1_+_169747788 1.028 PRRC2C
proline-rich coiled-coil 2C
chr11_+_64950402 1.027


chr6_-_10939095 1.024 NM_005906
MAK
male germ cell-associated kinase
chr13_+_112078633 1.014 NM_145248
C13orf28
chromosome 13 open reading frame 28
chr10_+_90414125 1.012 NM_001198828
NM_001198829
NM_001198830
NM_004190
LIPF



lipase, gastric



chr2_+_190248955 1.012 NM_144708
ANKAR
ankyrin and armadillo repeat containing
chr2_-_47969350 1.005 NM_025133
FBXO11
F-box protein 11
chr12_+_16397617 1.000 NM_145764
MGST1
microsomal glutathione S-transferase 1
chr2_+_225973845 0.995 NM_020864
KIAA1486
KIAA1486
chr11_-_5766621 0.987 NM_001001913
OR52N1
olfactory receptor, family 52, subfamily N, member 1
chr5_-_27074407 0.978 NM_016279
CDH9
cadherin 9, type 2 (T1-cadherin)
chr12_-_21818881 0.976 NM_004982
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr9_-_21207303 0.972 NM_002173
IFNA16
interferon, alpha 16
chr2_+_88966170 0.962


chr7_-_88262966 0.959 NM_152706
C7orf62
chromosome 7 open reading frame 62
chr1_+_184636326 0.958 NM_022375
OCLM
oculomedin
chr20_-_1420126 0.949 SIRPB2
signal-regulatory protein beta 2
chr3_-_110155237 0.945 NM_005459
GUCA1C
guanylate cyclase activator 1C
chr8_+_50147455 0.942 NM_001007176
C8orf22
chromosome 8 open reading frame 22
chr20_-_1420168 0.941 NM_001122962
NM_001134836
SIRPB2

signal-regulatory protein beta 2

chr6_+_127006298 0.940 LOC728666
PRELI domain containing 1 pseudogene
chr9_-_21358005 0.936 NM_006900
IFNA1
IFNA13
interferon, alpha 1
interferon, alpha 13
chr9_-_41944687 0.931 MGC21881
hypothetical locus MGC21881
chr6_-_49789204 0.927 NM_001142407
NM_001142408
NM_001142417
NM_001142435
NM_003296
CRISP2




cysteine-rich secretory protein 2




chr7_-_122126422 0.925 NM_139175
RNF133
ring finger protein 133
chr6_+_7347878 0.925 NM_153005
RIOK1
RIO kinase 1 (yeast)
chr14_-_105796268 0.918 ZCWPW2
IGHV3-23
IGKV3-20
zinc finger, CW type with PWWP domain 2
immunoglobulin heavy variable 3-23
immunoglobulin kappa variable 3-20
chr5_+_143171918 0.911 NM_021182
HMHB1
histocompatibility (minor) HB-1
chr2_+_210152609 0.900 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr16_+_24696069 0.899 TNRC6A
trinucleotide repeat containing 6A
chr4_+_130236731 0.895 NM_001099783
C4orf33
chromosome 4 open reading frame 33
chr5_-_37220702 0.890 C5orf42
chromosome 5 open reading frame 42
chr13_+_51496679 0.884 NM_021645
ALG11
UTP14C
asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast)
UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr13_-_32678142 0.884 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr12_+_56802 0.878 NM_015232
IQSEC3
IQ motif and Sec7 domain 3
chr4_-_39199527 0.877 UGDH
UDP-glucose 6-dehydrogenase
chr2_+_102744921 0.857 NM_144632
TMEM182
transmembrane protein 182
chr6_-_25679197 0.857


chr6_+_52159143 0.847 NM_002190
IL17A
interleukin 17A
chr13_+_51933228 0.839 CKAP2
cytoskeleton associated protein 2
chr12_-_43593977 0.829 NM_001145110
NELL2
NEL-like 2 (chicken)
chr13_+_48923688 0.828 NM_001160308
SETDB2
SET domain, bifurcated 2
chr11_-_55757236 0.817 NM_001004746
OR5T2
olfactory receptor, family 5, subfamily T, member 2
chr7_+_94135384 0.817 PEG10
paternally expressed 10
chr15_-_23201740 0.817 NM_130838
UBE3A
ubiquitin protein ligase E3A
chr15_+_42815851 0.816 NM_080745
NM_182985
TRIM69

tripartite motif containing 69

chr13_-_40454188 0.813 ELF1
E74-like factor 1 (ets domain transcription factor)
chr18_+_59733724 0.812 NM_005024
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr12_+_16391795 0.810 NM_020300
NM_145791
MGST1

microsomal glutathione S-transferase 1

chr5_-_160211623 0.807 NM_025153
ATP10B
ATPase, class V, type 10B
chr4_+_74825138 0.803 NM_000584
IL8
interleukin 8
chr1_-_156937065 0.802 NM_001005279
OR6K2
olfactory receptor, family 6, subfamily K, member 2
chr2_-_207291364 0.802 NM_001093730
DYTN
dystrotelin
chr4_+_74496660 0.800 ALB
albumin
chr21_+_37377116 0.797 NM_003316
TTC3
tetratricopeptide repeat domain 3
chr4_-_21155376 0.789 NM_001035004
KCNIP4
Kv channel interacting protein 4
chr3_+_191588354 0.787 NM_006580
CLDN16
claudin 16
chr2_+_228064531 0.787 AGFG1
ArfGAP with FG repeats 1
chr11_+_59580705 0.786 MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr15_-_39151468 0.777 INO80
INO80 homolog (S. cerevisiae)
chr12_+_28301399 0.767 NM_018318
CCDC91
coiled-coil domain containing 91
chr14_+_19365447 0.764 NM_001004723
OR4N2
olfactory receptor, family 4, subfamily N, member 2
chr11_-_92570693 0.764 NM_152313
SLC36A4
solute carrier family 36 (proton/amino acid symporter), member 4
chr11_+_54786233 0.762 NM_024114
TRIM48
tripartite motif containing 48
chr9_-_21067804 0.758 NM_002176
IFNB1
interferon, beta 1, fibroblast
chr6_-_119137923 0.750 NM_001178035
C6orf204
chromosome 6 open reading frame 204
chr2_+_196230096 0.748 NM_020342
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr8_+_50987149 0.746 NM_018967
SNTG1
syntrophin, gamma 1
chr6_-_71069347 0.745 NM_001851
COL9A1
collagen, type IX, alpha 1
chr5_+_140160966 0.743 NM_018906
NM_031497
PCDHA3

protocadherin alpha 3

chr11_-_83661878 0.741 NM_001142700
DLG2
discs, large homolog 2 (Drosophila)
chr12_-_38300109 0.739 NM_005164
ABCD2
ATP-binding cassette, sub-family D (ALD), member 2
chr4_-_186537145 0.737 NM_018409
LRP2BP
LRP2 binding protein
chr4_-_165338312 0.735 NM_012403
ANP32C
acidic (leucine-rich) nuclear phosphoprotein 32 family, member C
chr11_-_5964790 0.734 NM_001005173
OR52L1
olfactory receptor, family 52, subfamily L, member 1
chr14_-_20128228 0.732 NM_145250
RNASE11
ribonuclease, RNase A family, 11 (non-active)
chr1_+_114295289 0.732 NM_198269
HIPK1
homeodomain interacting protein kinase 1
chr12_-_23628774 0.729 NM_178010
SOX5
SRY (sex determining region Y)-box 5
chr1_+_103898844 0.728 NM_020978
AMY2B
amylase, alpha 2B (pancreatic)
chr10_-_69422391 0.722 HERC4
hect domain and RLD 4
chr2_+_79106333 0.721 NM_001008387
NM_198448
REG3G

regenerating islet-derived 3 gamma

chr4_+_169250281 0.720 NM_007193
ANXA10
annexin A10
chr11_+_86710076 0.718 TMEM135
transmembrane protein 135

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.09 1.27e-10 GO:0007608 sensory perception of smell
2.87 1.13e-09 GO:0007606 sensory perception of chemical stimulus
2.14 7.31e-07 GO:0007600 sensory perception
1.33 1.29e-05 GO:0032501 multicellular organismal process
1.62 2.41e-04 GO:0003008 system process
1.63 3.36e-03 GO:0050877 neurological system process
1.21 3.50e-02 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.56 1.71e-05 GO:0005576 extracellular region
1.30 1.30e-03 GO:0071944 cell periphery
1.26 1.28e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.18 1.64e-11 GO:0004984 olfactory receptor activity
1.98 1.11e-05 GO:0004930 G-protein coupled receptor activity
3.75 4.18e-03 GO:0004867 serine-type endopeptidase inhibitor activity
1.59 5.59e-03 GO:0004888 transmembrane receptor activity