Motif ID: CDX1,2,4.p2

Z-value: 1.744


Transcription factors associated with CDX1,2,4.p2:

Gene SymbolEntrez IDGene Name
CDX1 1044 caudal type homeobox 1
CDX2 1045 caudal type homeobox 2
CDX4 1046 caudal type homeobox 4



Activity profile for motif CDX1,2,4.p2.

activity profile for motif CDX1,2,4.p2


Sorted Z-values histogram for motif CDX1,2,4.p2

Sorted Z-values for motif CDX1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CDX1,2,4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_121117647 3.681 GSK3B
glycogen synthase kinase 3 beta
chr6_+_153060722 3.678 NM_025107
MYCT1
myc target 1
chr19_-_9087438 2.965 NM_001005192
OR7G1
olfactory receptor, family 7, subfamily G, member 1
chr4_+_70928718 2.946 NM_000200
HTN3
histatin 3
chr21_-_30791298 2.863 NM_181610
KRTAP19-4
keratin associated protein 19-4
chr8_-_7207899 2.826 NM_001164457
ZNF705G
zinc finger protein 705G
chr8_-_82522175 2.801 NM_002677
PMP2
peripheral myelin protein 2
chr10_-_98280299 2.705 TM9SF3
transmembrane 9 superfamily member 3
chr3_-_17716515 2.698 NM_001134381
TBC1D5
TBC1 domain family, member 5
chr12_+_26096757 2.683 NM_001164746
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr11_+_54867202 2.599 NM_001005274
OR4A16
olfactory receptor, family 4, subfamily A, member 16
chr10_+_90414125 2.586 NM_001198828
NM_001198829
NM_001198830
NM_004190
LIPF



lipase, gastric



chr17_+_58440629 2.478 NM_025185
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr12_-_44919818 2.461 SLC38A1
solute carrier family 38, member 1
chr3_+_150028130 2.315 NM_001871
CPB1
carboxypeptidase B1 (tissue)
chr12_-_11075272 2.232 NM_176885
TAS2R31
taste receptor, type 2, member 31
chr14_-_30927931 2.212 NM_015473
HEATR5A
HEAT repeat containing 5A
chr3_-_153541468 2.181 NM_001123228
TMEM14E
transmembrane protein 14E
chr1_-_21288259 2.060 EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr20_-_33783409 2.044 RBM39
RNA binding motif protein 39
chr6_+_64344307 2.043 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr9_-_21472311 2.033 NM_176891
IFNE
interferon, epsilon
chr10_-_27097782 2.031 ABI1
abl-interactor 1
chr11_-_7917642 2.016 NM_001003745
OR10A3
olfactory receptor, family 10, subfamily A, member 3
chr14_-_94677807 1.933 NM_030621
DICER1
dicer 1, ribonuclease type III
chr5_+_161427225 1.867 NM_000816
NM_198903
NM_198904
GABRG2


gamma-aminobutyric acid (GABA) A receptor, gamma 2


chr20_+_19818209 1.861 NM_018993
RIN2
Ras and Rab interactor 2
chr3_-_27473248 1.851 NM_003615
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr8_-_66863841 1.837 NM_002603
PDE7A
phosphodiesterase 7A
chr14_-_46190690 1.835 NM_080746
RPL10L
ribosomal protein L10-like
chr22_-_15682555 1.775 NM_175878
XKR3
XK, Kell blood group complex subunit-related family, member 3
chr4_+_71054492 1.774 NM_214711
C4orf40
chromosome 4 open reading frame 40
chr5_+_147628567 1.756 NM_001040129
SPINK13
serine peptidase inhibitor, Kazal type 13 (putative)
chr11_-_56137553 1.747 NM_001004740
OR5M1
olfactory receptor, family 5, subfamily M, member 1
chr1_-_178100204 1.718


chr2_-_40593074 1.704 NM_001112802
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr11_-_7775064 1.702 NM_153444
OR5P2
olfactory receptor, family 5, subfamily P, member 2
chr12_-_11106159 1.687 NM_176887
TAS2R46
taste receptor, type 2, member 46
chr2_-_215998181 1.684 FN1
fibronectin 1
chr11_+_55899675 1.667 NM_001005204
NM_001013356
OR8U1
OR8U8
olfactory receptor, family 8, subfamily U, member 1
olfactory receptor, family 8, subfamily U, member 8
chr6_+_126143971 1.658 NCOA7
nuclear receptor coactivator 7
chr3_+_63238854 1.650 NM_001130003
SYNPR
synaptoporin
chr1_+_28637247 1.638 NM_023923
PHACTR4
phosphatase and actin regulator 4
chr2_-_215967442 1.629 FN1
fibronectin 1
chr9_-_13240313 1.608 NM_003829
MPDZ
multiple PDZ domain protein
chr1_+_195123766 1.596 NM_006684
CFHR4
complement factor H-related 4
chr1_+_145892190 1.578 NM_001097616
GPR89C
G protein-coupled receptor 89C
chr8_-_17797127 1.565 NM_147203
NM_201553
NM_004467
NM_201552
FGL1



fibrinogen-like 1



chr1_+_114298021 1.551 NM_181358
HIPK1
homeodomain interacting protein kinase 1
chrX_-_139694248 1.545 NM_004065
CDR1
cerebellar degeneration-related protein 1, 34kDa
chr7_-_83108682 1.541 NM_001178129
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr13_+_77007809 1.535 NM_001160706
NM_003843
NM_144777
SCEL


sciellin


chr10_+_32896656 1.514 NM_024688
C10orf68
chromosome 10 open reading frame 68
chr12_-_78831821 1.510 NM_001143886
PPP1R12A
protein phosphatase 1, regulatory (inhibitor) subunit 12A
chr7_-_108311872 1.506 NM_001024607
C7orf66
chromosome 7 open reading frame 66
chrX_-_6463158 1.482 NM_016379
VCX2
VCX3A
variable charge, X-linked 2
variable charge, X-linked 3A
chr19_+_46762872 1.479 CEACAM21
carcinoembryonic antigen-related cell adhesion molecule 21
chr12_+_27066768 1.474 MED21
mediator complex subunit 21
chr4_+_71330797 1.473 NM_001145006
MUC7
mucin 7, secreted
chr15_-_54175954 1.471 RFX7
regulatory factor X, 7
chr4_+_71261066 1.455 NM_012390
SMR3B
SMR3A
submaxillary gland androgen regulated protein 3B
submaxillary gland androgen regulated protein 3A
chr3_-_38810504 1.446 NM_006514
SCN10A
sodium channel, voltage-gated, type X, alpha subunit
chr12_+_27066749 1.442 NM_004264
MED21
mediator complex subunit 21
chr4_-_153523113 1.422 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr1_-_188713324 1.419 NM_199051
FAM5C
family with sequence similarity 5, member C
chr3_-_106903734 1.413 CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr6_-_109795925 1.411 CD164
CD164 molecule, sialomucin
chr19_+_42409205 1.410 NM_152604
ZNF383
zinc finger protein 383
chr1_+_246635918 1.410 NM_030904
OR2T1
olfactory receptor, family 2, subfamily T, member 1
chr21_+_30690165 1.406 NM_181599
KRTAP13-1
keratin associated protein 13-1
chr8_+_17874128 1.389 PCM1
pericentriolar material 1
chr5_+_53787187 1.382 NM_006308
HSPB3
heat shock 27kDa protein 3
chr1_-_168310232 1.366 NM_014970
KIFAP3
kinesin-associated protein 3
chr2_+_61225710 1.354 NM_001143960
C2orf74
chromosome 2 open reading frame 74
chr10_+_97749837 1.352 NM_001001732
NM_001159747
CC2D2B

coiled-coil and C2 domain containing 2B

chrX_+_134803450 1.347 NM_018666
SAGE1
sarcoma antigen 1
chr5_-_114543632 1.335 NM_001017397
NM_001017398
NM_018700
TRIM36


tripartite motif containing 36


chr14_-_20098929 1.331 NM_001001673
NM_001110356
NM_001110357
NM_001110358
NM_001110359
NM_001110360
NM_001110361
RNASE9






ribonuclease, RNase A family, 9 (non-active)






chr7_+_6583560 1.330 NM_001134387
NM_001134388
NM_001134389
NM_018106
ZDHHC4



zinc finger, DHHC-type containing 4



chr13_+_49487390 1.315 NM_173605
NM_199464
TRIM13
KCNRG

tripartite motif containing 13
potassium channel regulator

chrX_+_75309165 1.301 NM_016500
CXorf26
chromosome X open reading frame 26
chr18_+_19706979 1.299 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr4_-_70760381 1.299 NM_005420
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr11_-_121492010 1.298 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr4_-_47678187 1.296 NM_001142564
CNGA1
cyclic nucleotide gated channel alpha 1
chr4_-_21155376 1.295 NM_001035004
KCNIP4
Kv channel interacting protein 4
chr10_-_98311813 1.291 TM9SF3
transmembrane 9 superfamily member 3
chr10_+_90336489 1.286 NM_001010939
LIPJ
lipase, family member J
chr3_-_161584137 1.285 NM_001190242
IFT80
intraflagellar transport 80 homolog (Chlamydomonas)
chr18_-_50134940 1.281 NM_139171
STARD6
StAR-related lipid transfer (START) domain containing 6
chr19_-_56946911 1.273 NM_001193306
NM_002029
FPR1

formyl peptide receptor 1

chr4_+_95595419 1.270 PDLIM5
PDZ and LIM domain 5
chr20_+_86121 1.268 NM_139074
DEFB127
defensin, beta 127
chr8_-_39814860 1.267 NM_001464
ADAM2
ADAM metallopeptidase domain 2
chr10_+_28918672 1.252 WAC
WW domain containing adaptor with coiled-coil
chr9_-_16717887 1.246 BNC2
basonuclin 2
chr2_-_215949566 1.246 FN1
fibronectin 1
chr9_-_21375258 1.246 NM_000605
IFNA2
interferon, alpha 2
chr9_-_69468634 1.233 NM_001126334
FOXD4L5
forkhead box D4-like 5
chr9_-_106407728 1.232 NM_001004481
OR13C2
olfactory receptor, family 13, subfamily C, member 2
chr12_-_10479810 1.231 NM_002260
KLRC2
KLRC3
killer cell lectin-like receptor subfamily C, member 2
killer cell lectin-like receptor subfamily C, member 3
chr1_+_190811479 1.229 NM_002922
RGS1
regulator of G-protein signaling 1
chr11_-_73882356 1.227 NM_001144869
LIPT2
lipoyl(octanoyl) transferase 2 (putative)
chr3_+_125296217 1.224 NM_001024660
NM_003947
KALRN

kalirin, RhoGEF kinase

chr12_+_70618892 1.223 NM_173353
TPH2
tryptophan hydroxylase 2
chr22_+_29696662 1.220


chr12_+_63090008 1.208 XPOT
exportin, tRNA (nuclear export receptor for tRNAs)
chr12_+_60940404 1.207 NM_006313
USP15
ubiquitin specific peptidase 15
chr12_+_8499788 1.206 NM_001007033
CLEC6A
C-type lectin domain family 6, member A
chr3_+_99334230 1.203 NM_001005338
OR5H1
olfactory receptor, family 5, subfamily H, member 1
chr6_-_138935359 1.201 NM_020464
NHSL1
NHS-like 1
chr1_-_148936123 1.200 NM_018178
GOLPH3L
golgi phosphoprotein 3-like
chr8_+_59486376 1.194 NM_001077619
UBXN2B
UBX domain protein 2B
chr3_-_109958723 1.191 NM_032579
RETNLB
resistin like beta
chr3_-_69381995 1.182 FRMD4B
FERM domain containing 4B
chr12_+_26017954 1.176 NM_001164747
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr15_-_48192804 1.176 ATP8B4
ATPase, class I, type 8B, member 4
chr2_+_190248955 1.174 NM_144708
ANKAR
ankyrin and armadillo repeat containing
chr21_-_30720100 1.169 NM_181622
KRTAP13-3
keratin associated protein 13-3
chr2_-_37397669 1.168 NM_005813
PRKD3
protein kinase D3
chr4_+_69996780 1.164 NM_001074
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr17_+_15843832 1.157 TTC19
tetratricopeptide repeat domain 19
chr15_-_68781662 1.155 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr4_+_71126376 1.153 NM_152997
C4orf7
chromosome 4 open reading frame 7
chr9_+_78305368 1.153 NM_001097636
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr15_+_46957556 1.145 NM_014335
EID1
EP300 interacting inhibitor of differentiation 1
chr11_+_26310253 1.139 NM_031418
ANO3
anoctamin 3
chr1_+_98899734 1.131 NM_015976
NM_152238
SNX7

sorting nexin 7

chr16_-_70080678 1.130 NM_006961
ZNF19
zinc finger protein 19
chr19_-_14853166 1.129 NM_030901
OR7A17
olfactory receptor, family 7, subfamily A, member 17
chr2_-_224574860 1.128 SERPINE2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr19_+_41872141 1.123 NM_152603
ZNF567
zinc finger protein 567
chr1_-_58920315 1.122


chr1_+_190871868 1.121 NM_002927
NM_144766
RGS13

regulator of G-protein signaling 13

chr2_-_45648608 1.110 SRBD1
S1 RNA binding domain 1
chr16_-_219339 1.104 NM_018032
NM_201412
LUC7L

LUC7-like (S. cerevisiae)

chr6_+_29663661 1.104 NM_007160
OR2H2
olfactory receptor, family 2, subfamily H, member 2
chr12_-_12740387 1.099 NM_006143
GPR19
G protein-coupled receptor 19
chr2_+_200879040 1.099 NM_001100422
NM_001100424
NM_001100423
SPATS2L


spermatogenesis associated, serine-rich 2-like


chr5_+_147754467 1.096 FBXO38
F-box protein 38
chr4_+_146250978 1.089 ABCE1
ATP-binding cassette, sub-family E (OABP), member 1
chr8_+_104900591 1.089 NM_014677
RIMS2
regulating synaptic membrane exocytosis 2
chr6_-_137536412 1.083 NM_052962
NM_181309
NM_181310
IL22RA2


interleukin 22 receptor, alpha 2


chr9_-_106401514 1.082 NM_001004482
OR13C5
olfactory receptor, family 13, subfamily C, member 5
chr18_-_46605730 1.080 NM_001127174
MRO
maestro
chr8_+_32623792 1.066 NM_013959
NRG1
neuregulin 1
chr22_-_43272567 1.054 NM_032287
LDOC1L
leucine zipper, down-regulated in cancer 1-like
chr12_-_10464308 1.051 NM_002261
NM_007333
KLRC3

killer cell lectin-like receptor subfamily C, member 3

chr13_-_38462857 1.051 NM_001144033
NM_145286
STOML3

stomatin (EPB72)-like 3

chr17_+_3065661 1.043 NM_014565
OR1A1
olfactory receptor, family 1, subfamily A, member 1
chr11_+_57285809 1.034 NM_001085458
NM_001085459
NM_001085460
NM_001085461
NM_001085462
NM_001085463
NM_001085464
NM_001085465
NM_001085466
NM_001085467
NM_001085468
NM_001085469
NM_001331
CTNND1












catenin (cadherin-associated protein), delta 1












chr17_-_31219943 1.033 NM_152781
C17orf66
chromosome 17 open reading frame 66
chrX_+_140753767 1.030 NM_138702
MAGEC3
melanoma antigen family C, 3
chr2_+_213857347 1.022 NM_001025436
NM_024532
SPAG16

sperm associated antigen 16

chr1_-_245988330 1.017 NM_012353
OR1C1
olfactory receptor, family 1, subfamily C, member 1
chr1_+_181421796 1.017 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr10_-_98021144 1.015 NM_001114094
NM_013314
BLNK

B-cell linker

chr4_-_123010918 1.013 NM_018190
NM_176824
BBS7

Bardet-Biedl syndrome 7

chr18_-_29882555 1.002 NM_001198549
NOL4
nucleolar protein 4
chr2_-_17563186 0.997 NM_001099218
RAD51AP2
RAD51 associated protein 2
chr12_-_7935010 0.997 SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14
chr6_+_26609427 0.995 NM_001732
BTN1A1
butyrophilin, subfamily 1, member A1
chr2_-_228206045 0.994 NM_001162483
NM_020161
C2orf83

chromosome 2 open reading frame 83

chr6_-_49820030 0.987 NM_001190986
NM_006061
CRISP3

cysteine-rich secretory protein 3

chr20_+_16676997 0.986 NM_020157
OTOR
otoraplin
chr5_+_159368733 0.984 NM_003314
TTC1
tetratricopeptide repeat domain 1
chr4_+_22608252 0.982


chr19_+_41418723 0.979 ZNF146
zinc finger protein 146
chr11_-_56101772 0.976 NM_001004741
OR5M10
olfactory receptor, family 5, subfamily M, member 10
chr19_+_12036513 0.975 NM_001136501
ZNF844
zinc finger protein 844
chrX_-_76700873 0.974 ATRX
alpha thalassemia/mental retardation syndrome X-linked
chr9_-_27287106 0.971 NM_001161585
NM_020641
C9orf11

chromosome 9 open reading frame 11

chr2_-_215951161 0.971 FN1
fibronectin 1
chr11_+_62813947 0.969 NM_001039752
SLC22A10
solute carrier family 22, member 10
chr3_-_78749633 0.961 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr8_-_78075834 0.958 NM_001172086
NM_001172087
PEX2

peroxisomal biogenesis factor 2

chr20_+_56912146 0.955 GNAS
GNAS complex locus
chr5_+_177368294 0.950 NM_001079527
FAM153C
family with sequence similarity 153, member C
chrX_+_22927998 0.950 NM_182699
DDX53
DEAD (Asp-Glu-Ala-Asp) box polypeptide 53
chr3_-_140879463 0.950 NM_178177
NMNAT3
nicotinamide nucleotide adenylyltransferase 3
chr14_+_78815406 0.948 NM_001105250
NM_138970
NRXN3

neurexin 3

chr5_+_159368721 0.948 TTC1
tetratricopeptide repeat domain 1
chr5_+_159368690 0.945 TTC1
tetratricopeptide repeat domain 1
chr21_-_30855478 0.936 NM_181614
KRTAP19-7
keratin associated protein 19-7
chr1_-_150599105 0.934 NM_001014342
FLG2
filaggrin family member 2
chr1_+_69998445 0.928 NM_020794
LRRC7
leucine rich repeat containing 7
chr12_+_8557402 0.926 NM_080387
CLEC4D
C-type lectin domain family 4, member D
chr12_+_74160779 0.921 NM_006851
GLIPR1
GLI pathogenesis-related 1
chr20_-_10148137 0.917 LOC100131208
similar to hCG2045825
chr6_+_62341966 0.916 NM_001190706
MTRNR2L9
MT-RNR2-like 9
chr4_+_154397975 0.915 TRIM2
tripartite motif containing 2
chr3_+_192661645 0.913 NM_001083308
PYDC2
pyrin domain containing 2
chr3_-_166278969 0.911 NM_001041
SI
sucrase-isomaltase (alpha-glucosidase)
chr4_+_115762971 0.909 NM_003360
UGT8
UDP glycosyltransferase 8
chr5_-_70621688 0.908 SMA4
glucuronidase, beta pseudogene
chr10_+_35496449 0.906 NM_182771
NM_182772
CREM

cAMP responsive element modulator

chr19_+_21371724 0.905 NM_001076678
NM_145326
NM_175910
ZNF493


zinc finger protein 493


chr1_+_111634996 0.904 NM_021797
NM_201653
CHIA

chitinase, acidic

chr9_-_34700062 0.903 NM_002989
CCL21
chemokine (C-C motif) ligand 21
chr4_+_47181987 0.899 NM_020453
ATP10D
ATPase, class V, type 10D

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.08 6.15e-36 GO:0007606 sensory perception of chemical stimulus
3.17 2.08e-34 GO:0007608 sensory perception of smell
2.14 4.63e-21 GO:0007600 sensory perception
1.57 6.51e-09 GO:0050877 neurological system process
1.43 3.07e-06 GO:0003008 system process
1.15 1.24e-03 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.20 2.07e-04 GO:0005886 plasma membrane
1.19 2.51e-04 GO:0071944 cell periphery

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.27 2.86e-36 GO:0004984 olfactory receptor activity
2.17 5.73e-24 GO:0004930 G-protein coupled receptor activity
1.75 4.68e-16 GO:0004888 transmembrane receptor activity
1.55 4.21e-12 GO:0004872 receptor activity
1.41 2.15e-08 GO:0004871 signal transducer activity
1.41 2.15e-08 GO:0060089 molecular transducer activity