Motif ID: E2F1..5.p2

Z-value: 1.708


Transcription factors associated with E2F1..5.p2:

Gene SymbolEntrez IDGene Name
E2F1 1869 E2F transcription factor 1
E2F2 1870 E2F transcription factor 2
E2F3 1871 E2F transcription factor 3
E2F4 1874 E2F transcription factor 4, p107/p130-binding
E2F5 1875 E2F transcription factor 5, p130-binding



Activity profile for motif E2F1..5.p2.

activity profile for motif E2F1..5.p2


Sorted Z-values histogram for motif E2F1..5.p2

Sorted Z-values for motif E2F1..5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of E2F1..5.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_120378052 2.915 NM_019071
NM_198267
ING3

inhibitor of growth family, member 3

chr10_+_62208256 2.545 CDK1
cyclin-dependent kinase 1
chr10_+_62208094 2.536 NM_001170406
NM_001170407
NM_001786
NM_033379
CDK1



cyclin-dependent kinase 1



chr2_+_173927783 2.156 NM_031942
NM_145810
CDCA7

cell division cycle associated 7

chr10_+_96295511 1.952 NM_018063
HELLS
helicase, lymphoid-specific
chr1_+_143920424 1.787 NM_203458
NOTCH2NL
notch 2 N-terminal like
chr7_+_93977267 1.605 CASD1
CAS1 domain containing 1
chr6_+_20510019 1.595 NM_001949
E2F3
E2F transcription factor 3
chr11_+_86426518 1.594 NM_001168724
NM_022918
TMEM135

transmembrane protein 135

chr1_+_26671548 1.552 HMGN2
high-mobility group nucleosomal binding domain 2
chr5_+_139473873 1.482 NM_005859
PURA
purine-rich element binding protein A
chrX_+_44617346 1.476 NM_021140
KDM6A
lysine (K)-specific demethylase 6A
chr2_+_48395271 1.464 NM_002158
FOXN2
forkhead box N2
chr1_+_113734997 1.423 NM_001142782
NM_152900
MAGI3

membrane associated guanylate kinase, WW and PDZ domain containing 3

chr5_+_56505608 1.419 GPBP1
GC-rich promoter binding protein 1
chr1_+_210848726 1.395 ATF3
activating transcription factor 3
chr1_+_210848763 1.345 ATF3
activating transcription factor 3
chr15_+_97923655 1.303 NM_001130926
NM_001130927
NM_001171894
NM_005587
MEF2A



myocyte enhancer factor 2A



chr13_+_97426713 1.293 IPO5
importin 5
chr1_+_6767968 1.260 NM_001195563
NM_015215
CAMTA1

calmodulin binding transcription activator 1

chr7_+_93976927 1.250 NM_022900
CASD1
CAS1 domain containing 1
chr13_+_33290254 1.246 RFC3
replication factor C (activator 1) 3, 38kDa
chr6_+_108988797 1.238 FOXO3
forkhead box O3
chr7_+_138695144 1.233 NM_016019
LUC7L2
LUC7-like 2 (S. cerevisiae)
chr15_+_97923702 1.226 MEF2A
myocyte enhancer factor 2A
chr10_+_112317401 1.209 NM_005445
SMC3
structural maintenance of chromosomes 3
chr1_+_93317374 1.198 NM_001164391
NM_001164392
NM_001164393
NM_007358
MTF2



metal response element binding transcription factor 2



chr7_+_32734244 1.194 LOC441208
zinc and ring finger 2 pseudogene
chr6_+_3966499 1.166 NM_003913
PRPF4B
PRP4 pre-mRNA processing factor 4 homolog B (yeast)
chr1_+_3558958 1.164 NM_005427
TP73
tumor protein p73
chr3_+_16901455 1.164 NM_001144382
PLCL2
phospholipase C-like 2
chr9_-_97119677 1.156 NM_000136
FANCC
Fanconi anemia, complementation group C
chr7_+_138695209 1.152 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr6_+_24883133 1.143 NM_015895
GMNN
geminin, DNA replication inhibitor
chr15_+_97923737 1.129 MEF2A
myocyte enhancer factor 2A
chr9_+_17124974 1.115 NM_001114395
NM_017738
CNTLN

centlein, centrosomal protein

chr5_-_39110235 1.108 RICTOR
RPTOR independent companion of MTOR, complex 2
chr17_+_26183074 1.108 NM_024857
ATAD5
ATPase family, AAA domain containing 5
chr1_+_210848592 1.107 NM_001040619
NM_001674
ATF3

activating transcription factor 3

chr2_+_219141761 1.103 NM_005444
RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr4_+_106287391 1.096 NM_001127208
NM_017628
TET2

tet oncogene family member 2

chr3_+_41215926 1.096 NM_001098209
NM_001098210
NM_001904
CTNNB1


catenin (cadherin-associated protein), beta 1, 88kDa


chr7_+_88226617 1.090 NM_181646
ZNF804B
zinc finger protein 804B
chr5_+_36912656 1.090 NIPBL
Nipped-B homolog (Drosophila)
chr7_+_138695236 1.082 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr20_-_35157744 1.079 RBL1
retinoblastoma-like 1 (p107)
chr12_-_61283474 1.066 NM_175895
C12orf61
chromosome 12 open reading frame 61
chr17_+_54997667 1.051 NM_001166301
NM_024612
DHX40

DEAH (Asp-Glu-Ala-His) box polypeptide 40

chr9_+_494661 1.042 NM_015158
KANK1
KN motif and ankyrin repeat domains 1
chr5_-_39110251 1.027 NM_152756
RICTOR
RPTOR independent companion of MTOR, complex 2
chr5_+_65476418 1.016 NM_139168
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr7_+_138695241 1.000 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr2_-_175754366 0.978 NM_001002258
NM_001190329
NM_001689
ATP5G3


ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)


chr4_+_72078126 0.972 NM_000788
DCK
deoxycytidine kinase
chr6_-_27914095 0.972 NM_003510
HIST1H2AK
histone cluster 1, H2ak
chr2_+_131966970 0.970 LOC150776
sphingomyelin phosphodiesterase 4, neutral membrane pseudogene
chr7_+_64136078 0.964 CCT6P3
chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr1_-_26105230 0.961 NM_203401
STMN1
stathmin 1
chr6_+_27208763 0.961 NM_021064
HIST1H2AG
histone cluster 1, H2ag
chr6_-_41971064 0.946 NM_018561
USP49
ubiquitin specific peptidase 49
chr4_+_72078255 0.935 DCK
deoxycytidine kinase
chr6_-_56816403 0.929 DST
dystonin
chr20_-_35157815 0.926 NM_002895
NM_183404
RBL1

retinoblastoma-like 1 (p107)

chr2_+_170149348 0.924 PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr1_+_115198977 0.915 NM_003176
SYCP1
synaptonemal complex protein 1
chr1_+_169721260 0.914 NM_015172
PRRC2C
proline-rich coiled-coil 2C
chr1_-_91260357 0.911 ZNF644
zinc finger protein 644
chr2_+_177785667 0.909 NM_194247
HNRNPA3P1
HNRNPA3
heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
heterogeneous nuclear ribonucleoprotein A3
chr5_+_56505412 0.906 NM_022913
GPBP1
GC-rich promoter binding protein 1
chr1_+_177261678 0.898 NM_014864
FAM20B
family with sequence similarity 20, member B
chr5_+_78568094 0.890


chr2_+_149118791 0.887 EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr6_+_44463418 0.884 CDC5L
CDC5 cell division cycle 5-like (S. pombe)
chr13_+_33290205 0.881 NM_002915
NM_181558
RFC3

replication factor C (activator 1) 3, 38kDa

chr7_+_86619805 0.876 NM_021145
DMTF1
cyclin D binding myb-like transcription factor 1
chr20_-_31737731 0.874 E2F1
E2F transcription factor 1
chr7_+_94123672 0.872 PEG10
paternally expressed 10
chr7_+_86619580 0.869 NM_001142326
NM_001142327
DMTF1

cyclin D binding myb-like transcription factor 1

chr2_+_149119029 0.863 NM_015630
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr14_+_85069217 0.856


chr2_+_171493870 0.841 NM_015530
GORASP2
golgi reassembly stacking protein 2, 55kDa
chr15_+_28705656 0.841 ARHGAP11B
Rho GTPase activating protein 11B
chr8_+_94998258 0.841 NM_018444
NM_001161780
NM_001161779
NM_001161781
PDP1



pyruvate dehyrogenase phosphatase catalytic subunit 1



chr6_-_27208507 0.839 NM_021058
HIST1H2BJ
histone cluster 1, H2bj
chr10_+_75580914 0.835 NM_006721
ADK
adenosine kinase
chr1_-_26105477 0.829 NM_001145454
NM_005563
STMN1

stathmin 1

chr13_-_109236897 0.825 NM_003749
IRS2
insulin receptor substrate 2
chr1_+_177261627 0.825 FAM20B
family with sequence similarity 20, member B
chr4_-_74154272 0.825 NM_173827
COX18
COX18 cytochrome c oxidase assembly homolog (S. cerevisiae)
chr2_+_153283381 0.822 ARL6IP6
ADP-ribosylation-like factor 6 interacting protein 6
chr5_+_36912595 0.818 NM_015384
NM_133433
NIPBL

Nipped-B homolog (Drosophila)

chr15_+_30694982 0.816 NM_014783
NM_199357
ARHGAP11A

Rho GTPase activating protein 11A

chr15_+_39739933 0.815 MGA
MAX gene associated
chr4_+_120353177 0.810


chr3_+_41215999 0.803 CTNNB1
catenin (cadherin-associated protein), beta 1, 88kDa
chr6_+_27914301 0.801 NM_003520
HIST1H2BN
histone cluster 1, H2bn
chr1_+_61320213 0.799 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr21_+_29592984 0.789 BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr14_+_34521945 0.784 SRP54
signal recognition particle 54kDa
chr15_+_39739864 0.783 NM_001080541
NM_001164273
MGA

MAX gene associated

chr2_-_219141199 0.781 NM_020935
USP37
ubiquitin specific peptidase 37
chr1_+_26671488 0.779 NM_005517
HMGN2
high-mobility group nucleosomal binding domain 2
chr5_-_36912487 0.779 LOC646719
hypothetical LOC646719
chr1_-_120413798 0.778 NM_024408
NOTCH2
notch 2
chr6_-_27883662 0.777 NM_003519
HIST1H2BL
histone cluster 1, H2bl
chr7_+_30291136 0.774 ZNRF2
zinc and ring finger 2
chr7_+_90063543 0.774 CDK14
cyclin-dependent kinase 14
chr13_+_78953495 0.771 NDFIP2
Nedd4 family interacting protein 2
chr6_+_108988761 0.769 NM_001455
FOXO3
forkhead box O3
chr13_+_78953367 0.763 NDFIP2
Nedd4 family interacting protein 2
chr11_+_125001063 0.763 CHEK1
CHK1 checkpoint homolog (S. pombe)
chr6_+_135544214 0.762 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr4_+_39734902 0.757 NM_018177
N4BP2
NEDD4 binding protein 2
chr22_+_18485068 0.753 RANBP1
RAN binding protein 1
chr6_+_44463265 0.750 NM_001253
CDC5L
CDC5 cell division cycle 5-like (S. pombe)
chr20_-_31737815 0.750 NM_005225
E2F1
E2F transcription factor 1
chr6_-_116681863 0.749 NM_021648
TSPYL4
TSPY-like 4
chr2_+_170149092 0.746 NM_004792
PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr7_-_106088565 0.743 NM_175884
FLJ36031
hypothetical protein FLJ36031
chr6_+_27883877 0.741 NM_003509
HIST1H2AI
HIST1H3F
histone cluster 1, H2ai
histone cluster 1, H3f
chr2_+_153283375 0.739 ARL6IP6
ADP-ribosylation-like factor 6 interacting protein 6
chr21_+_29593088 0.731 NM_001186
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr20_+_5879297 0.726 NM_032485
NM_182802
MCM8

minichromosome maintenance complex component 8

chr4_+_120353212 0.724 NM_019050
USP53
ubiquitin specific peptidase 53
chr1_+_109434896 0.722 NM_020141
TMEM167B
transmembrane protein 167B
chr13_+_78953258 0.722 NM_001161407
NM_019080
NDFIP2

Nedd4 family interacting protein 2

chr7_+_30291029 0.721 ZNRF2
zinc and ring finger 2
chr14_+_35365266 0.719 NM_032352
BRMS1L
breast cancer metastasis-suppressor 1-like
chr17_+_40089270 0.716 NM_001145080
C17orf104
chromosome 17 open reading frame 104
chr9_+_99785493 0.714 ANP32B
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr2_+_171494026 0.711 GORASP2
golgi reassembly stacking protein 2, 55kDa
chr15_+_54444907 0.708 NM_198524
TEX9
testis expressed 9
chr7_+_94123612 0.707 NM_001172437
NM_001172438
PEG10

paternally expressed 10

chr6_+_64403668 0.704 PHF3
PHD finger protein 3
chr15_+_42507057 0.700 CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr6_+_64403631 0.699 PHF3
PHD finger protein 3
chr1_+_52380633 0.697 NM_004799
NM_007323
NM_007324
ZFYVE9


zinc finger, FYVE domain containing 9


chr11_+_73981274 0.693 NM_006591
POLD3
polymerase (DNA-directed), delta 3, accessory subunit
chr6_+_64403685 0.692 PHF3
PHD finger protein 3
chr3_+_144203061 0.692 NM_001080415
U2SURP
U2 snRNP-associated SURP domain containing
chr5_-_74098641 0.690 NM_032380
NM_170681
NM_170691
GFM2


G elongation factor, mitochondrial 2


chr2_+_153283353 0.684 ARL6IP6
ADP-ribosylation-like factor 6 interacting protein 6
chr1_-_26105954 0.677 NM_203399
STMN1
stathmin 1
chr1_-_23730298 0.675 NM_004091
E2F2
E2F transcription factor 2
chr7_-_94123362 0.674 SGCE
sarcoglycan, epsilon
chr7_-_94123308 0.672 SGCE
sarcoglycan, epsilon
chr6_-_91353492 0.665 NM_003188
NM_145332
NM_145333
MAP3K7


mitogen-activated protein kinase kinase kinase 7


chr9_+_95253732 0.665 NM_014612
FAM120A
family with sequence similarity 120A
chr14_+_50776635 0.664 NM_030755
TMX1
thioredoxin-related transmembrane protein 1
chr1_+_28029922 0.660 PPP1R8
protein phosphatase 1, regulatory (inhibitor) subunit 8
chr9_-_103289154 0.660 NM_032342
C9orf125
chromosome 9 open reading frame 125
chr1_-_120413783 0.656 NOTCH2
notch 2
chr1_+_62675323 0.651 USP1
ubiquitin specific peptidase 1
chr4_+_148758014 0.650 TMEM184C
transmembrane protein 184C
chr21_+_29593098 0.650 BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr7_-_94123413 0.649 NM_001099400
NM_001099401
NM_003919
SGCE


sarcoglycan, epsilon


chr3_+_113180517 0.646 NM_018394
ABHD10
abhydrolase domain containing 10
chr6_+_139497933 0.645 NM_016217
HECA
headcase homolog (Drosophila)
chr1_+_28029909 0.640 PPP1R8
protein phosphatase 1, regulatory (inhibitor) subunit 8
chr10_+_13243553 0.639 NM_018518
NM_182751
MCM10

minichromosome maintenance complex component 10

chr7_+_94123556 0.638 NM_001040152
NM_001184961
NM_001184962
NM_015068
PEG10



paternally expressed 10



chr7_-_77163475 0.632


chr12_+_70519753 0.629 NM_001146213
NM_001146214
NM_022771
TBC1D15


TBC1 domain family, member 15


chr1_+_28029879 0.628 NM_002713
NM_014110
NM_138558
PPP1R8


protein phosphatase 1, regulatory (inhibitor) subunit 8


chr1_+_205992032 0.627 CD46
CD46 molecule, complement regulatory protein
chr4_+_152240182 0.626 NM_001006
RPS3A
ribosomal protein S3A
chr5_+_75414994 0.624 NM_014979
SV2C
synaptic vesicle glycoprotein 2C
chr1_+_62675296 0.624 USP1
ubiquitin specific peptidase 1
chr1_-_120413698 0.623 NOTCH2
notch 2
chr1_-_91260181 0.623 NM_032186
NM_201269
ZNF644

zinc finger protein 644

chr15_+_42507123 0.621 CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr1_-_39097904 0.620 NM_022157
RRAGC
Ras-related GTP binding C
chr17_+_26082779 0.619 SUZ12P
suppressor of zeste 12 homolog pseudogene
chr8_+_21833162 0.615 XPO7
exportin 7
chr22_+_18485145 0.614 RANBP1
RAN binding protein 1
chr6_+_64403936 0.613 PHF3
PHD finger protein 3
chr6_+_157141565 0.611 ARID1B
AT rich interactive domain 1B (SWI1-like)
chr4_+_148757958 0.610 NM_018241
TMEM184C
transmembrane protein 184C
chr7_-_151764004 0.606 NM_170606
MLL3
myeloid/lymphoid or mixed-lineage leukemia 3
chr6_+_163755773 0.606 QKI
quaking homolog, KH domain RNA binding (mouse)
chr2_+_64605049 0.595 AFTPH
aftiphilin
chr5_+_72287509 0.595 NM_001146032
NM_138782
FCHO2

FCH domain only 2

chr5_+_138657317 0.594 NM_001194955
NM_001194956
MATR3

matrin 3

chr20_-_48980858 0.592 NM_015339
NM_181442
ADNP

activity-dependent neuroprotector homeobox

chr11_+_9552005 0.590 WEE1
WEE1 homolog (S. pombe)
chr11_+_9551885 0.589 WEE1
WEE1 homolog (S. pombe)
chr5_+_138657229 0.588 NM_018834
MATR3
matrin 3
chrX_+_130985316 0.587 NM_001042452
MST4
serine/threonine protein kinase MST4
chr9_+_85785456 0.587 NM_024945
RMI1
RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae)
chr14_+_34521854 0.579 NM_001146282
NM_003136
SRP54

signal recognition particle 54kDa

chr1_+_100371293 0.579 NM_019083
CCDC76
coiled-coil domain containing 76
chr1_-_100370994 0.574 NM_194292
SASS6
spindle assembly 6 homolog (C. elegans)
chr8_+_21833111 0.574 NM_015024
XPO7
exportin 7
chr16_+_71256497 0.573


chr20_-_21326046 0.573 NM_033176
NKX2-4
NK2 homeobox 4
chr15_+_66133625 0.571 NM_016166
PIAS1
protein inhibitor of activated STAT, 1
chr20_+_36095263 0.570 NM_021215
RPRD1B
regulation of nuclear pre-mRNA domain containing 1B
chr6_+_27969181 0.570 NM_003527
HIST1H2BO
histone cluster 1, H2bo
chr9_-_122679387 0.569 NM_001009936
NM_015651
PHF19

PHD finger protein 19

chr5_+_72287625 0.569



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.47 1.99e-19 GO:0044260 cellular macromolecule metabolic process
1.64 2.48e-18 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.13 4.02e-17 GO:0007049 cell cycle
2.49 1.20e-16 GO:0051276 chromosome organization
1.68 1.07e-15 GO:0090304 nucleic acid metabolic process
1.32 3.15e-15 GO:0044237 cellular metabolic process
1.37 7.09e-14 GO:0043170 macromolecule metabolic process
1.50 2.44e-13 GO:0034641 cellular nitrogen compound metabolic process
1.47 1.45e-12 GO:0006807 nitrogen compound metabolic process
2.10 2.37e-12 GO:0022402 cell cycle process
1.73 2.62e-12 GO:0006996 organelle organization
4.37 7.09e-12 GO:0065004 protein-DNA complex assembly
2.18 7.34e-12 GO:0022403 cell cycle phase
4.25 8.51e-12 GO:0071824 protein-DNA complex subunit organization
1.28 8.57e-12 GO:0044238 primary metabolic process
1.15 1.15e-11 GO:0009987 cellular process
2.39 1.18e-10 GO:0006325 chromatin organization
3.69 3.36e-10 GO:0006333 chromatin assembly or disassembly
1.42 4.28e-10 GO:0016043 cellular component organization
1.41 4.31e-10 GO:0071840 cellular component organization or biogenesis
4.26 5.37e-10 GO:0031497 chromatin assembly
4.21 3.91e-09 GO:0006334 nucleosome assembly
1.23 4.84e-09 GO:0008152 metabolic process
2.02 6.72e-09 GO:0065003 macromolecular complex assembly
2.12 9.96e-09 GO:0006259 DNA metabolic process
3.93 1.48e-08 GO:0034728 nucleosome organization
2.10 2.93e-08 GO:0000278 mitotic cell cycle
1.44 3.59e-08 GO:0071841 cellular component organization or biogenesis at cellular level
1.71 7.53e-08 GO:0044085 cellular component biogenesis
3.46 8.86e-08 GO:0006323 DNA packaging
1.44 9.85e-08 GO:0071842 cellular component organization at cellular level
2.37 1.14e-07 GO:0034622 cellular macromolecular complex assembly
3.22 1.26e-07 GO:0071103 DNA conformation change
2.10 2.02e-07 GO:0016071 mRNA metabolic process
1.73 3.32e-07 GO:0022607 cellular component assembly
2.46 4.67e-07 GO:0051325 interphase
1.81 1.11e-06 GO:0043933 macromolecular complex subunit organization
1.53 1.20e-06 GO:0016070 RNA metabolic process
2.41 2.03e-06 GO:0051329 interphase of mitotic cell cycle
2.11 6.85e-06 GO:0000279 M phase
2.79 7.17e-06 GO:0006260 DNA replication
1.99 1.47e-05 GO:0006974 response to DNA damage stimulus
1.98 3.65e-05 GO:0034621 cellular macromolecular complex subunit organization
1.85 4.11e-05 GO:0006396 RNA processing
1.76 5.90e-05 GO:0071844 cellular component assembly at cellular level
1.45 7.10e-05 GO:0010467 gene expression
2.15 1.24e-04 GO:0006281 DNA repair
1.37 1.48e-04 GO:0044249 cellular biosynthetic process
1.46 2.09e-04 GO:0034645 cellular macromolecule biosynthetic process
2.05 2.44e-04 GO:0006397 mRNA processing
1.44 4.73e-04 GO:0009059 macromolecule biosynthetic process
1.78 5.24e-04 GO:0051726 regulation of cell cycle
2.73 7.67e-04 GO:0000082 G1/S transition of mitotic cell cycle
2.04 9.45e-04 GO:0051301 cell division
1.34 1.04e-03 GO:0009058 biosynthetic process
1.63 1.70e-03 GO:0033554 cellular response to stress
6.32 2.00e-03 GO:0000083 regulation of transcription involved in G1/S phase of mitotic cell cycle
2.11 2.06e-03 GO:0000280 nuclear division
2.11 2.06e-03 GO:0007067 mitosis
1.97 2.96e-03 GO:0016568 chromatin modification
1.32 3.79e-03 GO:0044267 cellular protein metabolic process
1.33 4.18e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.06 4.67e-03 GO:0000087 M phase of mitotic cell cycle
2.05 5.16e-03 GO:0048285 organelle fission
1.31 6.45e-03 GO:0010556 regulation of macromolecule biosynthetic process
6.32 7.31e-03 GO:0007062 sister chromatid cohesion
1.26 7.63e-03 GO:0060255 regulation of macromolecule metabolic process
2.76 9.41e-03 GO:0051320 S phase
2.01 1.10e-02 GO:0008380 RNA splicing
3.41 1.21e-02 GO:0031124 mRNA 3'-end processing
2.53 1.38e-02 GO:0006310 DNA recombination
2.24 1.55e-02 GO:0000375 RNA splicing, via transesterification reactions
1.66 1.87e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.29 1.92e-02 GO:0010468 regulation of gene expression
2.23 2.28e-02 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.23 2.28e-02 GO:0000398 nuclear mRNA splicing, via spliceosome
2.69 2.29e-02 GO:0000084 S phase of mitotic cell cycle
1.28 2.58e-02 GO:0031326 regulation of cellular biosynthetic process
1.28 2.92e-02 GO:0009889 regulation of biosynthetic process
1.50 3.27e-02 GO:0009892 negative regulation of metabolic process
2.57 3.36e-02 GO:0050657 nucleic acid transport
2.57 3.36e-02 GO:0050658 RNA transport
2.57 3.36e-02 GO:0051236 establishment of RNA localization
4.10 3.97e-02 GO:0051318 G1 phase
1.51 4.35e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.22 4.57e-02 GO:0031323 regulation of cellular metabolic process
2.89 4.63e-02 GO:0006402 mRNA catabolic process
1.61 4.99e-02 GO:0010558 negative regulation of macromolecule biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.34 5.65e-47 GO:0043229 intracellular organelle
1.34 6.46e-47 GO:0043226 organelle
1.37 2.02e-43 GO:0043227 membrane-bounded organelle
1.37 2.65e-43 GO:0043231 intracellular membrane-bounded organelle
1.54 6.37e-39 GO:0005634 nucleus
1.24 1.25e-37 GO:0044424 intracellular part
1.23 2.24e-37 GO:0005622 intracellular
1.48 1.98e-30 GO:0044446 intracellular organelle part
1.47 1.13e-29 GO:0044422 organelle part
1.91 4.61e-29 GO:0044428 nuclear part
1.79 1.19e-23 GO:0070013 intracellular organelle lumen
1.89 6.55e-23 GO:0031981 nuclear lumen
1.76 1.55e-22 GO:0043233 organelle lumen
1.75 2.34e-22 GO:0031974 membrane-enclosed lumen
2.03 6.43e-21 GO:0005654 nucleoplasm
2.51 1.17e-16 GO:0005694 chromosome
2.65 3.46e-16 GO:0044427 chromosomal part
3.36 1.74e-15 GO:0000785 chromatin
1.41 9.72e-12 GO:0032991 macromolecular complex
1.48 2.71e-11 GO:0043228 non-membrane-bounded organelle
1.48 2.71e-11 GO:0043232 intracellular non-membrane-bounded organelle
2.04 9.23e-11 GO:0044451 nucleoplasm part
3.78 7.05e-08 GO:0032993 protein-DNA complex
4.49 2.99e-07 GO:0000786 nucleosome
2.53 2.93e-06 GO:0016604 nuclear body
1.05 2.96e-06 GO:0044464 cell part
1.05 3.07e-06 GO:0005623 cell
1.15 1.07e-05 GO:0005737 cytoplasm
2.31 4.91e-05 GO:0005635 nuclear envelope
1.31 7.85e-05 GO:0043234 protein complex
2.23 1.19e-03 GO:0000228 nuclear chromosome
1.75 1.26e-03 GO:0030529 ribonucleoprotein complex
2.31 3.67e-03 GO:0044454 nuclear chromosome part
1.59 3.71e-03 GO:0031967 organelle envelope
1.58 4.13e-03 GO:0031975 envelope
2.34 1.06e-02 GO:0031965 nuclear membrane
2.38 1.58e-02 GO:0005681 spliceosomal complex
1.34 1.90e-02 GO:0012505 endomembrane system
2.30 2.02e-02 GO:0000775 chromosome, centromeric region
3.28 2.32e-02 GO:0034708 methyltransferase complex
3.28 2.32e-02 GO:0035097 histone methyltransferase complex
2.78 2.38e-02 GO:0000790 nuclear chromatin
2.38 3.05e-02 GO:0016607 nuclear speck
1.14 3.39e-02 GO:0044444 cytoplasmic part
3.45 4.64e-02 GO:0000792 heterochromatin
2.72 4.95e-02 GO:0071013 catalytic step 2 spliceosome

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.15 2.43e-16 GO:0005488 binding
1.51 4.29e-16 GO:0003676 nucleic acid binding
1.27 8.52e-16 GO:0005515 protein binding
1.53 4.66e-11 GO:0003677 DNA binding
1.45 1.30e-07 GO:0000166 nucleotide binding
1.39 2.08e-04 GO:0017076 purine nucleotide binding
1.39 3.35e-04 GO:0032553 ribonucleotide binding
1.39 3.35e-04 GO:0032555 purine ribonucleotide binding
1.43 3.74e-04 GO:0030554 adenyl nucleotide binding
1.43 4.22e-04 GO:0032559 adenyl ribonucleotide binding
1.38 6.00e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.60 8.30e-04 GO:0003723 RNA binding
1.42 1.04e-03 GO:0005524 ATP binding
3.89 1.84e-02 GO:0019205 nucleobase, nucleoside, nucleotide kinase activity
1.46 4.25e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups