Motif ID: EP300.p2

Z-value: 1.187


Transcription factors associated with EP300.p2:

Gene SymbolEntrez IDGene Name
EP300 2033 E1A binding protein p300



Activity profile for motif EP300.p2.

activity profile for motif EP300.p2


Sorted Z-values histogram for motif EP300.p2

Sorted Z-values for motif EP300.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EP300.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr21_+_44941514 1.321 NM_198699
KRTAP10-12
keratin associated protein 10-12
chr9_-_132804057 1.292 NM_032843
FIBCD1
fibrinogen C domain containing 1
chr8_-_145085616 1.250 NM_201384
PLEC
plectin
chr9_-_132803809 1.188 FIBCD1
fibrinogen C domain containing 1
chr2_+_232281491 1.075 PTMA
prothymosin, alpha
chr9_+_114552871 1.046 NM_001012994
SNX30
sorting nexin family member 30
chr8_-_23077392 0.926 NM_003840
TNFRSF10D
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
chr19_+_590878 0.907 NM_020637
FGF22
fibroblast growth factor 22
chr9_-_132804243 0.883 NM_001145106
FIBCD1
fibrinogen C domain containing 1
chr1_-_12599934 0.877 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr16_+_84204424 0.851 NM_014615
KIAA0182
KIAA0182
chr9_-_129729518 0.845 NM_173492
PIP5KL1
phosphatidylinositol-4-phosphate 5-kinase-like 1
chr19_-_51010272 0.787 NM_030785
RSPH6A
radial spoke head 6 homolog A (Chlamydomonas)
chr6_+_43846735 0.779 VEGFA
vascular endothelial growth factor A
chr14_-_104515738 0.747 NM_138420
AHNAK2
AHNAK nucleoprotein 2
chr2_+_96566190 0.735 NM_212481
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr7_+_7974941 0.727 NM_138426
GLCCI1
glucocorticoid induced transcript 1
chr7_+_128257698 0.726 NM_001127487
NM_001458
FLNC

filamin C, gamma

chr1_+_23990228 0.712 NM_007260
LYPLA2
lysophospholipase II
chr15_+_72695248 0.706 CLK3
CDC-like kinase 3
chr2_+_232281470 0.682 NM_001099285
NM_002823
PTMA

prothymosin, alpha

chr2_+_130846263 0.682 PTPN18
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
chr11_+_1925075 0.680 NM_021134
MRPL23
mitochondrial ribosomal protein L23
chr12_+_51727076 0.656 NM_198316
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chrX_-_19598912 0.645 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr10_-_5531401 0.643 NM_017422
CALML5
calmodulin-like 5
chr19_+_951295 0.632 NM_138690
GRIN3B
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
chr5_+_139155569 0.629 NM_032289
PSD2
pleckstrin and Sec7 domain containing 2
chr9_-_33437527 0.620 NM_004925
AQP3
aquaporin 3 (Gill blood group)
chr11_+_1925162 0.616 MRPL23
mitochondrial ribosomal protein L23
chr1_+_9571518 0.602 NM_001010866
NM_001130924
TMEM201

transmembrane protein 201

chr12_+_131577229 0.595 NM_001142641
FBRSL1
fibrosin-like 1
chr22_+_21852911 0.586 BCR
breakpoint cluster region
chr1_+_112852892 0.586 NM_024494
WNT2B
wingless-type MMTV integration site family, member 2B
chr16_-_342399 0.575 NM_003502
NM_181050
AXIN1

axin 1

chr12_+_52665196 0.572 NM_017409
HOXC10
homeobox C10
chr1_+_154878344 0.569 NM_021948
NM_198427
BCAN

brevican

chr20_-_61669550 0.567 NM_033405
PRIC285
peroxisomal proliferator-activated receptor A interacting complex 285
chr11_-_72111027 0.564 NM_001135190
NM_015242
ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr15_+_72906003 0.560 NM_001030005
CPLX3
complexin 3
chr17_-_975809 0.559 ABR
active BCR-related gene
chr2_+_20729904 0.547 NM_182828
GDF7
growth differentiation factor 7
chr15_+_66658626 0.540 NM_006091
CORO2B
coronin, actin binding protein, 2B
chr22_+_21870293 0.531


chr22_+_21852699 0.528 BCR
breakpoint cluster region
chr3_-_38046034 0.524 NM_006225
PLCD1
phospholipase C, delta 1
chr6_+_30018287 0.524 NM_002116
HLA-A
major histocompatibility complex, class I, A
chr15_+_72687765 0.520 NM_003992
CLK3
CDC-like kinase 3
chr19_+_18803742 0.520 NM_002911
UPF1
UPF1 regulator of nonsense transcripts homolog (yeast)
chr10_+_73703682 0.513 NM_019058
DDIT4
DNA-damage-inducible transcript 4
chr22_+_21852743 0.510 BCR
breakpoint cluster region
chr14_+_92049396 0.498 NM_024832
RIN3
Ras and Rab interactor 3
chr11_+_65236261 0.496 KAT5
K(lysine) acetyltransferase 5
chr1_+_41022066 0.496 NM_004700
NM_172163
KCNQ4

potassium voltage-gated channel, KQT-like subfamily, member 4

chr10_+_46413551 0.493 NM_014696
GPRIN2
G protein regulated inducer of neurite outgrowth 2
chr22_-_18635614 0.488 NM_023004
RTN4R
reticulon 4 receptor
chr6_+_29799095 0.487 NM_001098478
NM_001098479
NM_018950
HLA-F


major histocompatibility complex, class I, F


chr6_+_41622267 0.485 FOXP4
forkhead box P4
chr19_+_18803786 0.484 UPF1
UPF1 regulator of nonsense transcripts homolog (yeast)
chr1_+_18306823 0.482 NM_032880
IGSF21
immunoglobin superfamily, member 21
chrX_+_55495262 0.477 NM_014061
MAGEH1
melanoma antigen family H, 1
chr21_+_44569537 0.476 PFKL
phosphofructokinase, liver
chr11_-_64247230 0.471 NM_015080
NM_138732
NRXN2

neurexin 2

chr22_+_21852551 0.467 NM_004327
NM_021574
BCR

breakpoint cluster region

chr11_+_566482 0.463 NM_020901
PHRF1
PHD and ring finger domains 1
chr5_+_174084137 0.463 NM_002449
MSX2
msh homeobox 2
chr11_+_101693403 0.462 NM_001165
NM_182962
BIRC3

baculoviral IAP repeat containing 3

chr19_+_54786723 0.462 NM_020719
PRR12
proline rich 12
chr12_-_55310261 0.461 BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chr1_-_154205675 0.460 ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr16_+_66022729 0.455 HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr16_-_695719 0.449 NM_153350
FBXL16
F-box and leucine-rich repeat protein 16
chr11_-_1007140 0.444 MUC6
mucin 6, oligomeric mucus/gel-forming
chr16_+_2461500 0.438 NM_006181
NTN3
netrin 3
chr12_+_55896844 0.435 NM_007224
NXPH4
neurexophilin 4
chr16_+_80370426 0.435 NM_002661
PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr22_+_21817512 0.433 NM_004914
RAB36
RAB36, member RAS oncogene family
chr11_+_63864263 0.429 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr1_-_13712744 0.427 NM_001010847
LRRC38
leucine rich repeat containing 38
chr19_+_18560494 0.423 NM_001100418
NM_001100419
C19orf60

chromosome 19 open reading frame 60

chr7_+_97574054 0.423 NM_014916
LMTK2
lemur tyrosine kinase 2
chr1_-_16355013 0.422 NM_004431
EPHA2
EPH receptor A2
chr12_-_55920741 0.417 NM_020142
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr1_+_153317887 0.409 NM_004952
EFNA3
ephrin-A3
chr1_+_32251988 0.403 NM_006559
KHDRBS1
KH domain containing, RNA binding, signal transduction associated 1
chr19_+_45998020 0.402 NM_053046
EGLN2
egl nine homolog 2 (C. elegans)
chr9_+_137532294 0.397 NM_016034
MRPS2
mitochondrial ribosomal protein S2
chr17_+_24095135 0.390 NM_004295
TRAF4
TNF receptor-associated factor 4
chr10_-_70846573 0.390 NM_001057
TACR2
tachykinin receptor 2
chr22_-_43040063 0.388 NM_001099294
KIAA1644
KIAA1644
chr3_-_51971915 0.387 NM_033010
PCBP4
poly(rC) binding protein 4
chr8_-_134156437 0.384 SLA
Src-like-adaptor
chr7_+_45163891 0.382 NM_005856
RAMP3
receptor (G protein-coupled) activity modifying protein 3
chrX_+_48529905 0.381 NM_002049
GATA1
GATA binding protein 1 (globin transcription factor 1)
chr6_-_33822659 0.380 NM_001142883
NM_054111
IP6K3

inositol hexakisphosphate kinase 3

chr7_-_142293382 0.380 NM_018646
TRPV6
transient receptor potential cation channel, subfamily V, member 6
chr1_+_24755152 0.380 NM_001010980
C1orf130
chromosome 1 open reading frame 130
chr16_+_2023279 0.377 SLC9A3R2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr10_-_80875097 0.376 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr8_-_142307854 0.376 NM_001080431
SLC45A4
solute carrier family 45, member 4
chr10_-_49483002 0.373 NM_021226
ARHGAP22
Rho GTPase activating protein 22
chrX_-_131089552 0.372 NM_194277
FRMD7
FERM domain containing 7
chr19_+_52451642 0.371 CCDC9
coiled-coil domain containing 9
chr12_+_52806103 0.369 LOC400043
hypothetical LOC400043
chr20_+_34635362 0.369 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr17_-_24253821 0.365 NM_144683
DHRS13
dehydrogenase/reductase (SDR family) member 13
chr19_+_18391423 0.360


chr19_+_1358664 0.357 DAZAP1
DAZ associated protein 1
chr19_+_41039649 0.355 NM_032123
NM_199179
NM_199180
KIRREL2


kin of IRRE like 2 (Drosophila)


chr6_+_111409933 0.355 NM_032194
RPF2
ribosome production factor 2 homolog (S. cerevisiae)
chr11_+_47386621 0.355 NM_001128225
NM_152264
SLC39A13

solute carrier family 39 (zinc transporter), member 13

chr5_+_133478252 0.354 NM_003202
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr1_+_32346206 0.354 NM_012316
KPNA6
karyopherin alpha 6 (importin alpha 7)
chr9_+_126671321 0.353 ARPC5L
actin related protein 2/3 complex, subunit 5-like
chr1_+_36327039 0.351 NM_017825
ADPRHL2
ADP-ribosylhydrolase like 2
chr14_+_105028614 0.350 NM_001134875
NM_001134876
C14orf80

chromosome 14 open reading frame 80

chr19_+_1358531 0.349 NM_018959
NM_170711
DAZAP1

DAZ associated protein 1

chr1_+_179148935 0.347 NM_020950
KIAA1614
KIAA1614
chr20_+_43468046 0.345 NM_001197139
NM_001048221
NM_001048222
NM_001197140
NM_018478
DBNDD2




dysbindin (dystrobrevin binding protein 1) domain containing 2




chr1_-_23567084 0.342 NM_030634
ZNF436
zinc finger protein 436
chr3_+_48482625 0.341 TREX1
three prime repair exonuclease 1
chrX_+_67965517 0.341 NM_004429
EFNB1
ephrin-B1
chr1_+_151917674 0.340 NM_000906
NPR1
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
chr7_+_74877568 0.339 NSUN5P1
NOP2/Sun domain family, member 5 pseudogene 1
chr1_-_2451543 0.339 NM_001010926
HES5
hairy and enhancer of split 5 (Drosophila)
chr8_-_134156353 0.338 SLA
Src-like-adaptor
chr15_+_62921134 0.337 NM_001195059
NM_025201
PLEKHO2

pleckstrin homology domain containing, family O member 2

chr11_+_46679140 0.337 NM_001184751
ZNF408
zinc finger protein 408
chr3_+_46898673 0.335 NM_001184744
PTH1R
parathyroid hormone 1 receptor
chr9_+_139152595 0.334 GRIN1
glutamate receptor, ionotropic, N-methyl D-aspartate 1
chr19_+_1358604 0.333 DAZAP1
DAZ associated protein 1
chr5_+_176786279 0.333 NM_001004105
NM_001004106
NM_002082
GRK6


G protein-coupled receptor kinase 6


chr22_-_30356783 0.332 NM_014338
PISD
phosphatidylserine decarboxylase
chr20_-_29775354 0.332 BCL2L1
BCL2-like 1
chr22_+_18081968 0.331 NM_002688
SEPT5
septin 5
chr22_+_39404940 0.329 NM_005297
MCHR1
melanin-concentrating hormone receptor 1
chr11_-_6451561 0.328 NM_006458
NM_033278
TRIM3

tripartite motif containing 3

chr6_+_30565161 0.328 NM_005516
HLA-E
major histocompatibility complex, class I, E
chr19_+_12966970 0.326 NM_002501
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr11_+_66547391 0.325 NM_177963
SYT12
synaptotagmin XII
chr6_+_30018265 0.325 HLA-A
major histocompatibility complex, class I, A
chrX_+_69589081 0.322 DLG3
discs, large homolog 3 (Drosophila)
chr10_+_134060681 0.320 NM_001098637
NM_138499
PWWP2B

PWWP domain containing 2B

chr16_-_85099941 0.319 LOC400550
hypothetical LOC400550
chr19_+_10900502 0.317 C19orf52
chromosome 19 open reading frame 52
chr16_-_30274182 0.316 NM_006110
CD2BP2
CD2 (cytoplasmic tail) binding protein 2
chr6_-_31890765 0.316 NM_005527
HSPA1L
heat shock 70kDa protein 1-like
chrX_-_17789276 0.316 NM_001172732
NM_001172739
NM_001172743
NM_021785
RAI2



retinoic acid induced 2



chr21_+_41655786 0.315 NM_002463
LOC100131190
MX2
hypothetical protein LOC100131190
myxovirus (influenza virus) resistance 2 (mouse)
chr15_+_62539831 0.315 ZNF609
zinc finger protein 609
chr12_+_52653176 0.314 NM_014212
HOXC11
homeobox C11
chr7_-_155294518 0.313 SHH
sonic hedgehog
chr1_+_22176004 0.313 NM_007352
CELA3A
CELA3B
chymotrypsin-like elastase family, member 3A
chymotrypsin-like elastase family, member 3B
chr17_+_35075124 0.312 NM_003673
TCAP
titin-cap (telethonin)
chr17_+_35751796 0.311 NM_001024809
RARA
retinoic acid receptor, alpha
chrX_+_46977306 0.310 USP11
ubiquitin specific peptidase 11
chr12_+_48652886 0.310 NM_001652
AQP6
aquaporin 6, kidney specific
chrX_+_46977208 0.306 NM_004651
USP11
ubiquitin specific peptidase 11
chr22_-_49025499 0.306 NM_020461
TUBGCP6
tubulin, gamma complex associated protein 6
chr11_+_56984702 0.305 NM_178570
RTN4RL2
reticulon 4 receptor-like 2
chr12_-_122684150 0.305 NM_001414
EIF2B1
eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
chrX_-_151670754 0.305 NM_153488
MAGEA2B
MAGEA2
melanoma antigen family A, 2B
melanoma antigen family A, 2
chr6_-_31756119 0.305 NM_025262
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr12_-_113606322 0.304 NM_005996
NM_016569
TBX3

T-box 3

chr22_+_22907417 0.304 SUSD2
sushi domain containing 2
chr7_-_100331417 0.303 NM_000665
NM_015831
ACHE

acetylcholinesterase

chr9_-_116920232 0.303 NM_002160
TNC
tenascin C
chr22_-_20637188 0.302 PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr1_-_159275357 0.302 NM_001113205
NM_001113206
NM_001113207
TSTD1


F11R
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1


F11 receptor
chr1_+_199519202 0.300 NM_000299
NM_001005337
PKP1

plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)

chr15_+_72892205 0.300 NM_021819
LMAN1L
lectin, mannose-binding, 1 like
chr22_-_20637212 0.300 NM_014634
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr11_+_67563093 0.299 TCIRG1
T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
chr22_+_22907443 0.298 NM_019601
SUSD2
sushi domain containing 2
chrX_+_140819307 0.298 NM_005462
MAGEC1
melanoma antigen family C, 1
chr12_+_115833093 0.298 NM_012174
NM_153348
FBXW8

F-box and WD repeat domain containing 8

chr17_+_2646481 0.297 NM_001100398
NM_015085
RAP1GAP2

RAP1 GTPase activating protein 2

chr11_+_133599771 0.297 VPS26B
vacuolar protein sorting 26 homolog B (S. pombe)
chr18_+_30810889 0.296 NM_001143826
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr16_+_29892714 0.295 NM_004783
NM_016151
TAOK2

TAO kinase 2

chr22_-_27405708 0.295 NM_001145418
TTC28
tetratricopeptide repeat domain 28
chr1_-_159282312 0.294 USF1
upstream transcription factor 1
chr22_+_20251956 0.294 NM_003347
UBE2L3
ubiquitin-conjugating enzyme E2L 3
chr14_-_87859284 0.293 NM_138317
KCNK10
potassium channel, subfamily K, member 10
chr16_+_2145765 0.292 NM_032271
TRAF7
TNF receptor-associated factor 7
chr11_+_133599755 0.291 NM_052875
VPS26B
vacuolar protein sorting 26 homolog B (S. pombe)
chr22_-_20314274 0.291 NM_001017964
YDJC
YdjC homolog (bacterial)
chr11_+_133599689 0.289 VPS26B
vacuolar protein sorting 26 homolog B (S. pombe)
chr12_+_122684265 0.289 NM_001516
GTF2H3
general transcription factor IIH, polypeptide 3, 34kDa
chr15_+_88345612 0.289 NM_198526
ZNF710
zinc finger protein 710
chr1_+_203064397 0.288 NM_001005388
NM_001005389
NM_001160332
NM_001160333
NM_015090
NFASC




neurofascin




chr11_-_133599628 0.287 NM_015261
NCAPD3
non-SMC condensin II complex, subunit D3
chr3_+_128874458 0.286 NM_172027
ABTB1
ankyrin repeat and BTB (POZ) domain containing 1
chr22_+_18330049 0.286 NM_007310
COMT
catechol-O-methyltransferase
chr11_+_47386707 0.286 SLC39A13
solute carrier family 39 (zinc transporter), member 13
chr3_+_157874898 0.286 NM_015508
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr19_-_18749728 0.286


chr16_-_960796 0.283 LMF1
lipase maturation factor 1
chr22_+_20252004 0.281 UBE2L3
ubiquitin-conjugating enzyme E2L 3
chr9_-_131555111 0.280 NM_004878
PTGES
prostaglandin E synthase

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.19 2.15e-02 GO:0048518 positive regulation of biological process
1.10 2.75e-02 GO:0050794 regulation of cellular process
1.09 3.71e-02 GO:0065007 biological regulation

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.12 7.10e-06 GO:0005515 protein binding
1.05 5.55e-03 GO:0005488 binding