Motif ID: EVI1.p2

Z-value: 1.516


Transcription factors associated with EVI1.p2:

Gene SymbolEntrez IDGene Name
EVI1 2122 ecotropic viral integration site 1



Activity profile for motif EVI1.p2.

activity profile for motif EVI1.p2


Sorted Z-values histogram for motif EVI1.p2

Sorted Z-values for motif EVI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EVI1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_101581504 1.636 NM_022053
NXF2
nuclear RNA export factor 2
chr4_+_70928718 1.554 NM_000200
HTN3
histatin 3
chrX_+_101388810 1.342 NM_022053
NXF2
nuclear RNA export factor 2
chrX_-_119095544 1.338 NM_001099685
NM_032498
RHOXF2B
RHOXF2
Rhox homeobox family, member 2B
Rhox homeobox family, member 2
chr11_-_123816190 1.177 NM_012378
OR8B8
olfactory receptor, family 8, subfamily B, member 8
chr11_-_113935789 1.161 NM_152315
FAM55A
family with sequence similarity 55, member A
chrX_+_30169977 1.150 NM_002367
MAGEB4
melanoma antigen family B, 4
chrX_+_50670474 1.114 NM_005448
BMP15
bone morphogenetic protein 15
chr1_+_169326641 1.097 NM_001002294
NM_006894
FMO3

flavin containing monooxygenase 3

chrX_+_135558001 1.052 NM_000074
CD40LG
CD40 ligand
chr6_+_154373323 1.020 NM_001145279
NM_001145280
NM_001145281
OPRM1


opioid receptor, mu 1


chr12_+_20739555 0.975 NM_001145945
NM_001145946
NM_001145944
NM_017435
SLCO1C1



solute carrier organic anion transporter family, member 1C1



chr4_+_111053488 0.962 NM_001178130
NM_001178131
NM_001963
EGF


epidermal growth factor


chrX_-_24600661 0.961 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr4_-_40212670 0.945 NM_019027
RBM47
RNA binding motif protein 47
chr12_+_1608672 0.913 NM_032642
WNT5B
wingless-type MMTV integration site family, member 5B
chr13_+_77007809 0.899 NM_001160706
NM_003843
NM_144777
SCEL


sciellin


chr13_+_20081940 0.877


chr15_-_100280784 0.836 NM_001004195
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chrX_-_49852397 0.822 NM_003886
AKAP4
A kinase (PRKA) anchor protein 4
chr4_-_185963859 0.783 ACSL1
acyl-CoA synthetase long-chain family member 1
chr1_+_19807168 0.778


chr4_-_72868598 0.775 NM_000583
GC
group-specific component (vitamin D binding protein)
chr2_+_204440753 0.760 NM_001037631
NM_005214
CTLA4

cytotoxic T-lymphocyte-associated protein 4

chrX_+_15435351 0.756 NM_001721
BMX
BMX non-receptor tyrosine kinase
chr22_-_30885200 0.748 NM_001010859
C22orf42
chromosome 22 open reading frame 42
chr9_+_5646582 0.739 NM_020829
KIAA1432
KIAA1432
chr6_+_32515596 0.734 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr11_+_55554470 0.731 NM_001001921
OR5AS1
olfactory receptor, family 5, subfamily AS, member 1
chr9_-_85773899 0.715 HNRNPK
heterogeneous nuclear ribonucleoprotein K
chr11_-_104274606 0.706 NM_001191016
CASP12
caspase 12 (gene/pseudogene)
chr18_+_59733724 0.697 NM_005024
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr11_+_125208420 0.695 NM_001144874
PATE4
prostate and testis expressed 4
chr10_-_46039941 0.688 NM_001042357
NM_001042389
PTPN20B
PTPN20A
protein tyrosine phosphatase, non-receptor type 20B
protein tyrosine phosphatase, non-receptor type 20A
chr1_+_246591505 0.682 NM_001004696
OR2T4
olfactory receptor, family 2, subfamily T, member 4
chr3_+_123256902 0.671 NM_175862
CD86
CD86 molecule
chr6_-_110843432 0.662 NM_003649
NM_004032
DDO

D-aspartate oxidase

chr12_+_21059896 0.660 NM_001009562
LST-3TM12
organic anion transporter LST-3b
chr9_+_34642125 0.658 NM_001142784
IL11RA
interleukin 11 receptor, alpha
chr11_+_91724909 0.658 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr10_-_48426868 0.656 NM_001042357
NM_001042389
PTPN20B
PTPN20A
protein tyrosine phosphatase, non-receptor type 20B
protein tyrosine phosphatase, non-receptor type 20A
chrX_+_147608302 0.647 NM_001170628
AFF2
AF4/FMR2 family, member 2
chr3_+_150065732 0.636 NM_001870
CPA3
carboxypeptidase A3 (mast cell)
chr1_-_156078115 0.633 NM_005894
CD5L
CD5 molecule-like
chr13_+_48178620 0.633 NM_020377
CYSLTR2
cysteinyl leukotriene receptor 2
chr9_+_33230165 0.628 NM_014471
SPINK4
serine peptidase inhibitor, Kazal type 4
chr10_-_121286034 0.628 NM_002925
RGS10
regulator of G-protein signaling 10
chr9_+_124355211 0.624 NM_001004457
OR1N2
olfactory receptor, family 1, subfamily N, member 2
chr21_-_30836051 0.624 NM_181612
KRTAP19-6
keratin associated protein 19-6
chrX_-_23955223 0.620 NM_030624
KLHL15
kelch-like 15 (Drosophila)
chr19_+_59820413 0.605 NM_006669
LILRB1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr1_-_150599105 0.604 NM_001014342
FLG2
filaggrin family member 2
chr22_+_38652555 0.603 GRAP2
GRB2-related adaptor protein 2
chr1_+_169171235 0.600 NM_001163629
NM_025063
C1orf129

chromosome 1 open reading frame 129

chr8_+_42671718 0.597 NM_000749
CHRNB3
cholinergic receptor, nicotinic, beta 3
chr12_-_48017223 0.596 NM_001008223
C1QL4
complement component 1, q subcomponent-like 4
chr1_-_32157845 0.588 NM_001195100
NM_001195101
PTP4A2

protein tyrosine phosphatase type IVA, member 2

chr1_+_12325632 0.580 VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr22_-_37214480 0.580 NM_001098505
NM_030881
DDX17

DEAD (Asp-Glu-Ala-Asp) box polypeptide 17

chr22_+_34443863 0.579 NM_030642
APOL5
apolipoprotein L, 5
chr11_-_49960646 0.568 NM_001005270
OR4C12
olfactory receptor, family 4, subfamily C, member 12
chr6_-_64087806 0.567 NM_001143940
NM_016571
LGSN

lengsin, lens protein with glutamine synthetase domain

chr22_-_40941254 0.564 NM_005650
NM_181492
TCF20

transcription factor 20 (AR1)

chr12_-_242255 0.564 NM_001190997
NM_016615
SLC6A13

solute carrier family 6 (neurotransmitter transporter, GABA), member 13

chr7_+_18296569 0.564 HDAC9
histone deacetylase 9
chr3_-_58175437 0.563 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr8_-_114518194 0.552 NM_052900
NM_198123
CSMD3

CUB and Sushi multiple domains 3

chr15_-_62460622 0.548 NM_001029989
NM_014736
KIAA0101

KIAA0101

chr3_-_48634192 0.547 NM_001008269
TMEM89
transmembrane protein 89
chr11_+_59902530 0.542 NM_021201
NM_206938
NM_206939
NM_206940
MS4A7



membrane-spanning 4-domains, subfamily A, member 7



chr11_+_57554977 0.541 NM_001005186
OR6Q1
olfactory receptor, family 6, subfamily Q, member 1
chr19_-_15252261 0.539 NM_014299
NM_058243
BRD4

bromodomain containing 4

chrX_+_30171768 0.537 NM_002363
NM_177415
MAGEB1

melanoma antigen family B, 1

chr12_-_14024187 0.537 NM_000834
GRIN2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr22_-_30018329 0.535 NM_001135911
NM_052880
PIK3IP1

phosphoinositide-3-kinase interacting protein 1

chr11_+_59902598 0.532 MS4A7
membrane-spanning 4-domains, subfamily A, member 7
chrX_+_150653873 0.528 NM_005140
CNGA2
cyclic nucleotide gated channel alpha 2
chr5_-_88004891 0.527 LOC645323
hypothetical LOC645323
chrX_-_115508164 0.523 NM_001017978
CXorf61
chromosome X open reading frame 61
chr10_+_57028755 0.518 NM_001190478
MTRNR2L5
MT-RNR2-like 5
chr19_-_10152056 0.517


chr1_-_9040141 0.510 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr4_+_71096830 0.510 NM_017855
ODAM
odontogenic, ameloblast asssociated
chr11_-_55460451 0.506 NM_006637
OR5I1
olfactory receptor, family 5, subfamily I, member 1
chr5_+_56545657 0.502 NM_001127236
GPBP1
GC-rich promoter binding protein 1
chr17_-_35911340 0.497 NM_032865
TNS4
tensin 4
chrX_+_154880439 0.488 NM_002186
IL9R
interleukin 9 receptor
chr1_-_151352587 0.476 NM_001014450
SPRR2A
SPRR2F
small proline-rich protein 2A
small proline-rich protein 2F
chr5_-_146441184 0.476 NM_181677
NM_181678
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chrX_+_14457340 0.475 NM_001118885
NM_001118886
NM_001171942
NM_002063
GLRA2



glycine receptor, alpha 2



chr12_-_53328402 0.475 NM_053283
DCD
dermcidin
chr5_-_114543632 0.475 NM_001017397
NM_001017398
NM_018700
TRIM36


tripartite motif containing 36


chr5_+_175444454 0.473 NM_001079529
FAM153B
family with sequence similarity 153, member B
chr5_+_125723686 0.470 NM_001146319
GRAMD3
GRAM domain containing 3
chr12_+_56802 0.469 NM_015232
IQSEC3
IQ motif and Sec7 domain 3
chr17_+_8865547 0.464 NM_004822
NTN1
netrin 1
chr1_-_150044365 0.461 NM_001004432
LINGO4
leucine rich repeat and Ig domain containing 4
chrX_-_134764397 0.460 NM_001017436
CT45A3
CT45A4
CT45A2
cancer/testis antigen family 45, member A3
cancer/testis antigen family 45, member A4
cancer/testis antigen family 45, member A2
chr18_+_59405513 0.458 NM_012397
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr10_-_17211795 0.457 NM_001081
CUBN
cubilin (intrinsic factor-cobalamin receptor)
chr10_+_106024638 0.456 GSTO2
glutathione S-transferase omega 2
chr4_-_100284395 0.452 NM_000670
ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide
chr12_+_55674496 0.446 NM_007264
GPR182
G protein-coupled receptor 182
chr11_+_55629094 0.443 NM_001005200
OR8H2
olfactory receptor, family 8, subfamily H, member 2
chrX_-_102418329 0.442 NM_001012979
TCEAL5
transcription elongation factor A (SII)-like 5
chr9_-_26995649 0.441 NM_022901
LRRC19
leucine rich repeat containing 19
chr3_-_194755281 0.439 NM_032279
ATP13A4
ATPase type 13A4
chr1_-_144426918 0.439 NM_007053
CD160
CD160 molecule
chr1_+_246468853 0.439 NM_017504
OR2M4
olfactory receptor, family 2, subfamily M, member 4
chr3_+_137224266 0.434 NM_181897
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr13_+_110637173 0.434 NM_001113513
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr3_-_187562470 0.433 NM_001080744
NM_001080745
NM_001346
DGKG


diacylglycerol kinase, gamma 90kDa


chr10_-_91092410 0.432 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr8_+_110443881 0.432 NM_177531
PKHD1L1
polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1
chr6_+_153060722 0.428 NM_025107
MYCT1
myc target 1
chr6_-_132987106 0.428 NM_001033080
TAAR2
trace amine associated receptor 2
chr4_+_91375204 0.423 NM_207491
FAM190A
family with sequence similarity 190, member A
chr9_-_106420305 0.422 NM_001001956
OR13C9
olfactory receptor, family 13, subfamily C, member 9
chrX_+_37777730 0.422 NM_001163334
SYTL5
synaptotagmin-like 5
chr19_+_6086650 0.420 NM_030924
ACSBG2
acyl-CoA synthetase bubblegum family member 2
chr22_-_29290875 0.419 NM_004861
GAL3ST1
galactose-3-O-sulfotransferase 1
chr7_-_75876830 0.416 NM_080744
SRCRB4D
scavenger receptor cysteine rich domain containing, group B (4 domains)
chr14_+_54291255 0.415 NM_001161577
SAMD4A
sterile alpha motif domain containing 4A
chr11_+_103412517 0.414 NM_001001711
DDI1
DNA-damage inducible 1 homolog 1 (S. cerevisiae)
chr8_+_118216517 0.414 NM_001172814
NM_173851
SLC30A8

solute carrier family 30 (zinc transporter), member 8

chr10_+_90474280 0.409 NM_001080518
LIPK
lipase, family member K
chr7_-_122627235 0.409 NM_022444
SLC13A1
solute carrier family 13 (sodium/sulfate symporters), member 1
chr5_-_36036883 0.403 NM_001171873
UGT3A1
UDP glycosyltransferase 3 family, polypeptide A1
chr12_+_7755316 0.399 NM_199286
DPPA3
STELLAR
developmental pluripotency associated 3
developmental pluripotency associated 3 pseudogene
chr1_-_104040308 0.397 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr7_+_142053693 0.395 NM_001190487
MTRNR2L6
MT-RNR2-like 6
chr9_-_72926333 0.394 NM_001007471
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr3_-_45858566 0.393 NM_020347
LZTFL1
leucine zipper transcription factor-like 1
chr19_+_60006877 0.390 NM_001080770
NM_001080772
NM_002255
KIR2DL4


killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4


chr16_-_24876357 0.388 ARHGAP17
Rho GTPase activating protein 17
chr12_-_10870134 0.386 NM_023921
TAS2R10
taste receptor, type 2, member 10
chr19_+_53189719 0.385 NM_022142
ELSPBP1
epididymal sperm binding protein 1
chr20_+_9146036 0.385 NM_182797
PLCB4
phospholipase C, beta 4
chr2_+_191009265 0.385 MFSD6
major facilitator superfamily domain containing 6
chr19_-_20636152 0.384 NM_001076675
NM_145297
ZNF626

zinc finger protein 626

chr9_-_129381086 0.382 NM_001035534
FAM129B
family with sequence similarity 129, member B
chr6_-_76027286 0.381 TMEM30A
transmembrane protein 30A
chr14_+_75058518 0.381 NM_006399
BATF
basic leucine zipper transcription factor, ATF-like
chrX_-_10548458 0.380 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr5_-_36337756 0.379 NM_001161429
NM_145000
RANBP3L

RAN binding protein 3-like

chr12_-_98072602 0.378 NM_020140
NM_181670
ANKS1B

ankyrin repeat and sterile alpha motif domain containing 1B

chr9_+_71134060 0.378 NM_004816
FAM189A2
family with sequence similarity 189, member A2
chr9_-_8723893 0.378 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr12_-_9976173 0.376 NM_001130711
CLEC2A
C-type lectin domain family 2, member A
chr1_-_150353179 0.373 NM_007113
TCHH
trichohyalin
chrX_+_149364377 0.371 NM_001177466
NM_005491
MAMLD1

mastermind-like domain containing 1

chr14_-_73250094 0.366 NM_006029
PNMA1
paraneoplastic antigen MA1
chr12_+_26096757 0.364 NM_001164746
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr4_-_75066533 0.362 NM_002619
PF4
platelet factor 4
chr4_+_71235259 0.361 NM_033122
CABS1
calcium-binding protein, spermatid-specific 1
chr1_+_165957780 0.361 NM_001146191
NM_003953
NM_024569
MPZL1


myelin protein zero-like 1


chr14_+_75058591 0.360 BATF
basic leucine zipper transcription factor, ATF-like
chr10_+_106024876 0.360 NM_001191014
NM_001191015
GSTO2

glutathione S-transferase omega 2

chrX_+_129301493 0.360 NM_003951
NM_022810
SLC25A14

solute carrier family 25 (mitochondrial carrier, brain), member 14

chrX_+_135210787 0.357 NM_153834
GPR112
G protein-coupled receptor 112
chrX_-_43626537 0.355 NM_000898
MAOB
monoamine oxidase B
chr19_-_62680703 0.355 NM_001024596
NM_001144068
ZNF772

zinc finger protein 772

chr15_+_71953020 0.355 NM_153356
TBC1D21
TBC1 domain family, member 21
chr10_+_115929008 0.354 NM_198795
TDRD1
tudor domain containing 1
chr12_+_887272 0.352 WNK1
WNK lysine deficient protein kinase 1
chr4_-_157006827 0.351 NM_017419
ACCN5
amiloride-sensitive cation channel 5, intestinal
chr11_-_62753574 0.348 NM_199352
SLC22A25
solute carrier family 22, member 25
chr14_+_98247702 0.345 NM_182560
C14orf177
chromosome 14 open reading frame 177
chr9_-_99746923 0.345 NM_018437
HEMGN
hemogen
chr18_-_58946858 0.345 BCL2
B-cell CLL/lymphoma 2
chr21_-_31012965 0.343 NM_001164435
KRTAP21-3
keratin associated protein 21-3
chr6_+_46822657 0.343 NM_001162435
LOC100287718
ankyrin repeat domain containing gene
chr13_-_109600709 0.341 COL4A1
collagen, type IV, alpha 1
chr5_-_151764857 0.341 NM_020167
NMUR2
neuromedin U receptor 2
chr3_-_49204294 0.341 NM_001080528
LOC646498
hypothetical protein LOC646498
chr11_-_55815113 0.339 NM_001005199
OR8H1
olfactory receptor, family 8, subfamily H, member 1
chr3_-_152449591 0.337 NM_001081455
P2RY14
purinergic receptor P2Y, G-protein coupled, 14
chr11_+_12917369 0.337 TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr5_+_161045235 0.336 NM_000811
GABRA6
gamma-aminobutyric acid (GABA) A receptor, alpha 6
chr12_-_21649019 0.336 NM_021957
GYS2
glycogen synthase 2 (liver)
chr12_-_53044495 0.335 NM_020370
GPR84
G protein-coupled receptor 84
chr12_+_111829121 0.334 NM_001032409
NM_002534
NM_016816
OAS1


2',5'-oligoadenylate synthetase 1, 40/46kDa


chr19_-_52427698 0.334 NM_001127240
NM_001127241
NM_001127242
BBC3


BCL2 binding component 3


chr14_-_57133361 0.333 NM_001080455
SLC35F4
solute carrier family 35, member F4
chr3_-_38967055 0.331 NM_014139
SCN11A
sodium channel, voltage-gated, type XI, alpha subunit
chr1_-_32054164 0.331 NM_144569
SPOCD1
SPOC domain containing 1
chr3_-_193928038 0.329 NM_004113
FGF12
fibroblast growth factor 12
chr1_+_213245507 0.329 NM_001017424
KCNK2
potassium channel, subfamily K, member 2
chr3_-_120861959 0.328 NM_022135
POPDC2
popeye domain containing 2
chr3_+_162697289 0.327 NM_001080440
OTOL1
otolin 1 homolog (zebrafish)
chr11_+_48241988 0.326 NM_001004726
OR4X1
olfactory receptor, family 4, subfamily X, member 1
chr3_-_109958723 0.325 NM_032579
RETNLB
resistin like beta
chrX_-_55225668 0.323 NM_001190708
MTRNR2L10
MT-RNR2-like 10
chr5_+_121493113 0.322 NM_207317
ZNF474
zinc finger protein 474
chr1_+_158426908 0.322 NM_001231
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr1_+_103999824 0.319 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr5_-_146869613 0.318 DPYSL3
dihydropyrimidinase-like 3
chr12_-_15757114 0.317 EPS8
epidermal growth factor receptor pathway substrate 8
chr1_-_165112157 0.317 NM_053053
TADA1
transcriptional adaptor 1
chr9_+_78305368 0.317 NM_001097636
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.83 4.27e-15 GO:0007608 sensory perception of smell
2.62 1.41e-13 GO:0007606 sensory perception of chemical stimulus
1.98 2.02e-09 GO:0007600 sensory perception
1.68 9.20e-08 GO:0050877 neurological system process
1.24 3.56e-07 GO:0050896 response to stimulus
1.55 1.70e-06 GO:0003008 system process
1.26 3.27e-06 GO:0032501 multicellular organismal process
8.88 2.95e-02 GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.44 1.59e-15 GO:0005886 plasma membrane
1.44 2.43e-15 GO:0071944 cell periphery
1.28 8.82e-12 GO:0044425 membrane part
1.30 2.36e-10 GO:0031224 intrinsic to membrane
1.29 1.43e-09 GO:0016021 integral to membrane
1.21 3.78e-09 GO:0016020 membrane
1.38 1.43e-04 GO:0044459 plasma membrane part
1.34 2.86e-03 GO:0005576 extracellular region

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.89 6.36e-16 GO:0004984 olfactory receptor activity
2.18 4.36e-15 GO:0004930 G-protein coupled receptor activity
1.88 1.33e-13 GO:0004888 transmembrane receptor activity
1.71 1.13e-12 GO:0004872 receptor activity
1.59 6.24e-11 GO:0004871 signal transducer activity
1.59 6.24e-11 GO:0060089 molecular transducer activity