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Motif ID: FEV.p2

Z-value: 1.376

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr22_-_29694186	1.205	NM_014941	MORC2	MORC family CW-type zinc finger 2
chr18_+_3443771	1.164	NM_173211	TGIF1	TGFB-induced factor homeobox 1
chr14_+_38720085	1.075		PNN	pinin, desmosome associated protein
chr12_+_68028407	1.038		LYZ	lysozyme
chr2_-_21084077	1.037		APOB	apolipoprotein B (including Ag(x) antigen)
chr2_+_171280944	0.943		SP5	Sp5 transcription factor
chr6_+_153060722	0.922	NM_025107	MYCT1	myc target 1
chr5_+_72830029	0.912		BTF3	basic transcription factor 3
chr14_+_38719462	0.912		PNN	pinin, desmosome associated protein
chr2_+_206732562	0.881	NM_001037663 NM_001959 NM_021121	EEF1B2	eukaryotic translation elongation factor 1 beta 2
chr2_+_118562499	0.859	NM_016133	INSIG2	insulin induced gene 2
chr3_+_134976965	0.855		TF	transferrin
chr3_+_52296893	0.833		GLYCTK	glycerate kinase
chr4_+_152417774	0.818	NM_183375	PRSS48	protease, serine, 48
chr3_+_52296875	0.795	NM_001144951 NM_145262	GLYCTK	glycerate kinase
chr3_+_120495906	0.774	NM_020754	ARHGAP31	Rho GTPase activating protein 31
chr18_+_30875297	0.730	NM_014268	MAPRE2	microtubule-associated protein, RP/EB family, member 2
chr14_+_23686547	0.703		RNF31	ring finger protein 31
chr14_-_24047261	0.701	NM_001836	CMA1	chymase 1, mast cell
chr5_+_139485703	0.698	NM_001007189	C5orf53	chromosome 5 open reading frame 53
chr10_+_31650069	0.696	NM_001128128 NM_001174094	ZEB1	zinc finger E-box binding homeobox 1
chr6_+_126282078	0.666		NCOA7	nuclear receptor coactivator 7
chr2_+_206732859	0.664		EEF1B2	eukaryotic translation elongation factor 1 beta 2
chr2_+_206732575	0.663		EEF1B2	eukaryotic translation elongation factor 1 beta 2
chr5_+_72830003	0.654	NM_001037637 NM_001207	BTF3	basic transcription factor 3
chr20_-_33750457	0.649	NM_001198989 NM_021100	NFS1	NFS1 nitrogen fixation 1 homolog (S. cerevisiae)
chr16_+_3273522	0.638		ZNF263	zinc finger protein 263
chr14_+_23008723	0.630	NM_001042635 NM_015514	NGDN	neuroguidin, EIF4E binding protein
chr9_+_70926009	0.624	NM_001170414	TJP2	tight junction protein 2 (zona occludens 2)
chr14_+_62740878	0.612	NM_020663	RHOJ	ras homolog gene family, member J
chr2_+_27848085	0.600	NM_004891 NM_145330	MRPL33	mitochondrial ribosomal protein L33
chr19_-_4510713	0.599		SEMA6B	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr2_+_27848090	0.598		MRPL33	mitochondrial ribosomal protein L33
chr12_-_9123126	0.598		A2M	alpha-2-macroglobulin
chr2_-_21084911	0.589		APOB	apolipoprotein B (including Ag(x) antigen)
chr16_+_3273369	0.585	NM_005741	ZNF263	zinc finger protein 263
chr14_+_23008742	0.576		NGDN	neuroguidin, EIF4E binding protein
chr17_+_55269974	0.568
chr14_+_89792646	0.563	NM_002802	PSMC1	proteasome (prosome, macropain) 26S subunit, ATPase, 1
chr6_+_142510094	0.562	NM_016485	VTA1	Vps20-associated 1 homolog (S. cerevisiae)
chr12_+_68028397	0.562	NM_000239	LYZ	lysozyme
chr20_+_33750645	0.555	NM_080748	ROMO1	reactive oxygen species modulator 1
chr2_-_213724577	0.548	NM_001079526	IKZF2	IKAROS family zinc finger 2 (Helios)
chr6_+_142510075	0.540		VTA1	Vps20-associated 1 homolog (S. cerevisiae)
chr2_+_233633279	0.538	NM_001017915 NM_005541	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa
chr16_-_23371952	0.538	NM_153603	COG7	component of oligomeric golgi complex 7
chr2_+_233633348	0.537		INPP5D	inositol polyphosphate-5-phosphatase, 145kDa
chr20_+_19818209	0.536	NM_018993	RIN2	Ras and Rab interactor 2
chr11_-_17147863	0.536	NM_002645	PIK3C2A	phosphoinositide-3-kinase, class 2, alpha polypeptide
chr14_+_34831294	0.533	NM_002791	PSMA6	proteasome (prosome, macropain) subunit, alpha type, 6
chr20_+_55359706	0.532		RAE1	RAE1 RNA export 1 homolog (S. pombe)
chr20_+_43423990	0.532	NM_001197129	SYS1	SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr5_+_109053507	0.521		MAN2A1	mannosidase, alpha, class 2A, member 1
chr20_+_60395515	0.516	NM_001024	RPS21	ribosomal protein S21
chr3_+_192529567	0.515	NM_174908 NM_178335	CCDC50	coiled-coil domain containing 50
chr14_+_73073570	0.514	NM_001037161	ACOT1	acyl-CoA thioesterase 1
chr14_+_54104383	0.512	NM_001161576 NM_015589	SAMD4A	sterile alpha motif domain containing 4A
chr3_+_134947788	0.510		TF	transferrin
chr2_+_218992053	0.509	NM_007127	VIL1	villin 1
chr13_+_110653407	0.506		ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7
chr2_-_55698393	0.501		SMEK2	SMEK homolog 2, suppressor of mek1 (Dictyostelium)
chr20_+_48560326	0.499		PTPN1	protein tyrosine phosphatase, non-receptor type 1
chr3_+_144203061	0.498	NM_001080415	U2SURP	U2 snRNP-associated SURP domain containing
chr16_-_74239030	0.488	NM_001130089 NM_005548	KARS	lysyl-tRNA synthetase
chr14_-_56805118	0.482
chr2_+_108571177	0.481	NM_004987	LIMS1	LIM and senescent cell antigen-like domains 1
chr14_+_56805358	0.481	NM_018229	MUDENG	MU-2/AP1M2 domain containing, death-inducing
chr14_-_37795290	0.480	NM_175060	CLEC14A	C-type lectin domain family 14, member A
chr20_+_55359551	0.478	NM_003610	RAE1	RAE1 RNA export 1 homolog (S. pombe)
chr5_+_109053628	0.478		MAN2A1	mannosidase, alpha, class 2A, member 1
chr2_+_108571209	0.477		LIMS1	LIM and senescent cell antigen-like domains 1
chr2_-_206732348	0.470	NM_005006	NDUFS1	NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr14_-_23727826	0.469		IPO4	importin 4
chr2_+_108604111	0.468	NM_001193484	LIMS1	LIM and senescent cell antigen-like domains 1
chr20_+_48560327	0.464		PTPN1	protein tyrosine phosphatase, non-receptor type 1
chr20_+_19946008	0.461		NAA20	N(alpha)-acetyltransferase 20, NatB catalytic subunit
chr14_-_56805367	0.459	NM_006544	EXOC5	exocyst complex component 5
chr14_-_21172837	0.454	NM_001005466	OR10G2	olfactory receptor, family 10, subfamily G, member 2
chr20_+_35351473	0.453		MANBAL	mannosidase, beta A, lysosomal-like
chr6_+_2711227	0.453		WRNIP1	Werner helicase interacting protein 1
chr20_+_21231921	0.451	NM_012255	XRN2	5'-3' exoribonuclease 2
chr6_+_10663934	0.449	NM_001491	GCNT2	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr2_+_138438277	0.447	NM_001024074 NM_001024075 NM_006895	HNMT	histamine N-methyltransferase
chr10_+_124310170	0.442	NM_004406 NM_007329 NM_017579	DMBT1	deleted in malignant brain tumors 1
chr14_-_56805309	0.442		EXOC5	exocyst complex component 5
chr3_-_11598829	0.442	NM_001128220	VGLL4	vestigial like 4 (Drosophila)
chr16_-_57309625	0.438		GOT2	glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)
chr14_+_23686498	0.437	NM_017999	RNF31	ring finger protein 31
chr3_-_71625318	0.433		FOXP1	forkhead box P1
chr20_-_51633042	0.432	NM_006526	ZNF217	zinc finger protein 217
chr3_+_32834513	0.430	NM_001039111	TRIM71	tripartite motif containing 71
chr2_+_108571336	0.430	NM_001193488	LIMS1	LIM and senescent cell antigen-like domains 1
chr2_+_148495043	0.427	NM_018328	MBD5	methyl-CpG binding domain protein 5
chr20_+_19945993	0.422		NAA20	N(alpha)-acetyltransferase 20, NatB catalytic subunit
chr7_-_107997132	0.418	NM_182529 NM_001130475	THAP5	THAP domain containing 5
chr14_+_54104099	0.414		SAMD4A	sterile alpha motif domain containing 4A
chr2_+_74007495	0.413		DGUOK	deoxyguanosine kinase
chr7_+_107997544	0.412	NM_012328	DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9
chr14_-_56805280	0.412		EXOC5	exocyst complex component 5
chr14_+_20527971	0.411		METTL17	methyltransferase like 17
chr20_+_16658608	0.409	NM_003092 NM_198220	SNRPB2	small nuclear ribonucleoprotein polypeptide B
chr20_+_42537927	0.408	NM_001039199 NM_024331	TTPAL	tocopherol (alpha) transfer protein-like
chr5_+_65258250	0.406		ERBB2IP	erbb2 interacting protein
chr2_+_74007523	0.405		DGUOK	deoxyguanosine kinase
chr3_+_120496180	0.403		ARHGAP31	Rho GTPase activating protein 31
chr6_-_111995213	0.402	NM_001164283	TRAF3IP2	TRAF3 interacting protein 2
chr20_+_19945949	0.402		NAA20	N(alpha)-acetyltransferase 20, NatB catalytic subunit
chr2_-_148494732	0.402	NM_001190882 NM_001190879 NM_002552 NM_001190881 NM_181741	ORC4	origin recognition complex, subunit 4
chr6_+_3966499	0.402	NM_003913	PRPF4B	PRP4 pre-mRNA processing factor 4 homolog B (yeast)
chr14_-_23727850	0.401	NM_024658	IPO4	importin 4
chr4_+_119825983	0.401	NM_020961	METTL14	methyltransferase like 14
chr3_-_114176401	0.399	NM_138806 NM_138939 NM_138940 NM_170780	CD200R1	CD200 receptor 1
chr7_+_5051977	0.394	NM_021163	RBAK	RB-associated KRAB zinc finger
chr16_+_80086454	0.392	NM_030629	CMIP	c-Maf-inducing protein
chr3_-_11585264	0.392	NM_001128221	VGLL4	vestigial like 4 (Drosophila)
chr15_+_75500284	0.391	NM_018200	HMG20A	high-mobility group 20A
chr6_+_142510034	0.391		VTA1	Vps20-associated 1 homolog (S. cerevisiae)
chr9_+_76893232	0.388		OSTF1	osteoclast stimulating factor 1
chr2_+_165858586	0.387	NM_021007	SCN2A	sodium channel, voltage-gated, type II, alpha subunit
chr8_+_9450849	0.385	NM_003747	TNKS	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr14_+_22634621	0.385	NM_017924	C14orf119	chromosome 14 open reading frame 119
chr12_+_6950342	0.382		EMG1	EMG1 nucleolar protein homolog (S. cerevisiae)
chr16_+_75782870	0.382		MON1B	MON1 homolog B (yeast)
chr11_+_101485946	0.381	NM_001130145 NM_001195044 NM_006106	YAP1	Yes-associated protein 1
chr20_+_19815075	0.377		RIN2	Ras and Rab interactor 2
chr14_+_34831355	0.372		PSMA6	proteasome (prosome, macropain) subunit, alpha type, 6
chr17_+_72827227	0.371		SEPT9	septin 9
chr14_+_22634585	0.371		C14orf119	chromosome 14 open reading frame 119
chr2_-_225519974	0.369		DOCK10	dedicator of cytokinesis 10
chr2_+_187162969	0.367	NM_001145000 NM_002210	ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
chr5_+_38881719	0.367	NM_003999	OSMR	oncostatin M receptor
chr4_+_2783764	0.366		SH3BP2	SH3-domain binding protein 2
chr7_-_107667728	0.365	NM_001037132	NRCAM	neuronal cell adhesion molecule
chr1_+_93317374	0.364	NM_001164391 NM_001164392 NM_001164393 NM_007358	MTF2	metal response element binding transcription factor 2
chr14_+_19365447	0.364	NM_001004723	OR4N2	olfactory receptor, family 4, subfamily N, member 2
chr16_+_74239135	0.363	NM_018975	TERF2IP	telomeric repeat binding factor 2, interacting protein
chr7_+_6735911	0.362
chr4_+_140806536	0.362		MGST2	microsomal glutathione S-transferase 2
chr20_+_55359992	0.361	NM_001015885	RAE1	RAE1 RNA export 1 homolog (S. pombe)
chr22_+_44446410	0.360		ATXN10	ataxin 10
chr20_+_19945930	0.359	NM_016100 NM_181528	NAA20	N(alpha)-acetyltransferase 20, NatB catalytic subunit
chr17_+_69941430	0.358	NM_018653	GPRC5C	G protein-coupled receptor, family C, group 5, member C
chr1_+_93584051	0.357		DR1	down-regulator of transcription 1, TBP-binding (negative cofactor 2)
chr8_+_9450832	0.356		TNKS	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr2_+_33514896	0.355	NM_170672	RASGRP3	RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr4_+_2783743	0.352	NM_001145855	SH3BP2	SH3-domain binding protein 2
chr8_-_28803341	0.349	NM_001172562	INTS9	integrator complex subunit 9
chr6_-_42527760	0.349	NM_033502	TRERF1	transcriptional regulating factor 1
chr1_+_93584064	0.349	NM_001938	DR1	down-regulator of transcription 1, TBP-binding (negative cofactor 2)
chr16_-_11852862	0.349	NM_015659	RSL1D1	ribosomal L1 domain containing 1
chr2_+_201806410	0.349	NM_001080124 NM_001228 NM_033355 NM_033358	CASP8	caspase 8, apoptosis-related cysteine peptidase
chr6_+_153113624	0.348	NM_003381 NM_194435	VIP	vasoactive intestinal peptide
chr6_-_28519207	0.347	NM_001012455	ZSCAN23	zinc finger and SCAN domain containing 23
chr18_+_11841388	0.345	NM_020412	CHMP1B	chromatin modifying protein 1B
chr17_+_72827185	0.345	NM_006640	SEPT9	septin 9
chr9_+_79158164	0.343		VPS13A	vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr1_+_93584088	0.342		DR1	down-regulator of transcription 1, TBP-binding (negative cofactor 2)
chr16_+_29994797	0.341		PPP4C	protein phosphatase 4, catalytic subunit
chr2_-_65447370	0.341	NM_001128210	SPRED2	sprouty-related, EVH1 domain containing 2
chr3_+_134947573	0.340	NM_001063	TF	transferrin
chr8_-_82557956	0.337	NM_001442	FABP4	fatty acid binding protein 4, adipocyte
chr11_-_72111027	0.335	NM_001135190 NM_015242	ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr21_+_29318782	0.333	NM_001001992 NM_001032410 NM_006447	USP16	ubiquitin specific peptidase 16
chr16_+_29994818	0.333		PPP4C	protein phosphatase 4, catalytic subunit
chr7_+_93388951	0.333	NM_004126	GNG11	guanine nucleotide binding protein (G protein), gamma 11
chr8_-_79880095	0.330	NM_000880	IL7	interleukin 7
chr2_+_187163232	0.330		ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
chr14_+_20527804	0.329	NM_001029991 NM_022734	METTL17	methyltransferase like 17
chr8_+_9450800	0.328		TNKS	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr16_+_29994843	0.328	NM_002720	PPP4C	protein phosphatase 4, catalytic subunit
chr15_+_91244422	0.327	NM_001042572 NM_001271	CHD2	chromodomain helicase DNA binding protein 2
chr2_+_60962228	0.326	NM_002908	REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr6_+_138230045	0.325	NM_006290	TNFAIP3	tumor necrosis factor, alpha-induced protein 3
chr7_+_107997527	0.325		DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9
chr1_-_93583910	0.323		LOC100131564	hypothetical LOC100131564
chr10_-_18988172	0.323
chr19_+_46121963	0.320		CYP2B7P1	cytochrome P450, family 2, subfamily B, polypeptide 7 pseudogene 1
chr9_+_71009746	0.320	NM_001170415 NM_001170416	TJP2	tight junction protein 2 (zona occludens 2)
chr10_+_97879457	0.318	NM_014803	ZNF518A	zinc finger protein 518A
chr5_+_65258316	0.316		ERBB2IP	erbb2 interacting protein
chr20_+_1047216	0.316	NM_006814	PSMF1	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr10_+_18988282	0.316	NM_178815	ARL5B	ADP-ribosylation factor-like 5B
chr1_+_22224571	0.315		HSPC157	hypothetical LOC29092
chr14_+_69303556	0.315		SRSF5	serine/arginine-rich splicing factor 5
chr14_-_23686269	0.314		PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr14_+_69303563	0.313		SRSF5	serine/arginine-rich splicing factor 5
chr3_-_88281705	0.313	NM_001195308	CGGBP1	CGG triplet repeat binding protein 1
chr17_-_55511056	0.311	NM_022070	HEATR6	HEAT repeat containing 6
chr9_+_114288899	0.310	NM_133465	KIAA1958	KIAA1958
chr15_+_91244563	0.310		CHD2	chromodomain helicase DNA binding protein 2
chr5_-_38881636	0.309
chr14_+_69303565	0.307	NM_001039465 NM_006925	SRSF5	serine/arginine-rich splicing factor 5
chr9_+_114289178	0.307		KIAA1958	KIAA1958
chr14_-_19553191	0.306	NM_001004712	OR4K14	olfactory receptor, family 4, subfamily K, member 14
chr16_+_8799170	0.306	NM_000303	PMM2	phosphomannomutase 2
chr14_-_36121536	0.306	NM_014360	NKX2-8	NK2 homeobox 8
chr9_+_70926205	0.306		TJP2	tight junction protein 2 (zona occludens 2)
chr5_+_112340326	0.305	NM_152624	DCP2	DCP2 decapping enzyme homolog (S. cerevisiae)
chr12_+_67426225	0.305		SLC35E3	solute carrier family 35, member E3
chr16_+_69115189	0.304	NM_012426	SF3B3	splicing factor 3b, subunit 3, 130kDa

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.31	2.26e-10	GO:0090304	nucleic acid metabolic process
1.35	8.66e-10	GO:0016070	RNA metabolic process
1.26	1.23e-09	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.18	2.34e-08	GO:0044260	cellular macromolecule metabolic process
1.31	2.47e-08	GO:0010467	gene expression
1.15	4.77e-06	GO:0043170	macromolecule metabolic process
1.29	7.88e-06	GO:0009059	macromolecule biosynthetic process
1.29	9.88e-06	GO:0034645	cellular macromolecule biosynthetic process
1.38	1.88e-05	GO:0032774	RNA biosynthetic process
1.19	4.25e-05	GO:0034641	cellular nitrogen compound metabolic process
1.56	9.31e-05	GO:0016032	viral reproduction
1.17	2.81e-04	GO:0006807	nitrogen compound metabolic process
1.36	4.91e-04	GO:0006351	transcription, DNA-dependent
1.11	6.98e-04	GO:0044237	cellular metabolic process
1.44	1.60e-03	GO:0016071	mRNA metabolic process
2.08	1.71e-03	GO:0050851	antigen receptor-mediated signaling pathway
2.21	1.81e-03	GO:0050852	T cell receptor signaling pathway
1.28	4.42e-03	GO:0044085	cellular component biogenesis
1.43	6.34e-03	GO:0001775	cell activation
1.49	6.91e-03	GO:0006397	mRNA processing
1.10	9.82e-03	GO:0044238	primary metabolic process
1.05	1.10e-02	GO:0009987	cellular process
1.93	1.13e-02	GO:0002768	immune response-regulating cell surface receptor signaling pathway
1.50	1.13e-02	GO:0044419	interspecies interaction between organisms
1.91	2.38e-02	GO:0002429	immune response-activating cell surface receptor signaling pathway
1.31	2.80e-02	GO:0043933	macromolecular complex subunit organization

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.08	4.67e-09	GO:0044424	intracellular part
1.27	1.66e-08	GO:0044428	nuclear part
1.26	1.97e-08	GO:0043233	organelle lumen
1.07	2.30e-08	GO:0005622	intracellular
1.25	4.62e-08	GO:0031974	membrane-enclosed lumen
1.28	3.29e-07	GO:0031981	nuclear lumen
1.24	4.39e-07	GO:0070013	intracellular organelle lumen
1.18	3.62e-06	GO:0032991	macromolecular complex
1.03	2.51e-05	GO:0044464	cell part
1.03	2.67e-05	GO:0005623	cell
1.19	3.08e-05	GO:0043228	non-membrane-bounded organelle
1.19	3.08e-05	GO:0043232	intracellular non-membrane-bounded organelle
1.12	4.46e-05	GO:0005634	nucleus
1.12	6.51e-05	GO:0044446	intracellular organelle part
1.07	8.55e-05	GO:0043226	organelle
1.07	9.54e-05	GO:0043229	intracellular organelle
1.08	1.49e-04	GO:0043227	membrane-bounded organelle
1.08	1.50e-04	GO:0043231	intracellular membrane-bounded organelle
1.27	2.10e-04	GO:0005654	nucleoplasm
1.11	2.20e-04	GO:0044422	organelle part
1.08	6.83e-04	GO:0005737	cytoplasm
1.72	7.60e-04	GO:0031252	cell leading edge
1.16	9.91e-04	GO:0043234	protein complex
1.19	1.85e-03	GO:0005829	cytosol
1.40	2.36e-03	GO:0030529	ribonucleoprotein complex
1.37	1.66e-02	GO:0005730	nucleolus
1.67	2.03e-02	GO:0044445	cytosolic part
2.17	2.25e-02	GO:0005793	ER-Golgi intermediate compartment
1.29	2.52e-02	GO:0044451	nucleoplasm part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.14	2.73e-12	GO:0005515	protein binding
1.34	7.17e-04	GO:0003723	RNA binding