Motif ID: FOSL2.p2

Z-value: 1.286


Transcription factors associated with FOSL2.p2:

Gene SymbolEntrez IDGene Name
FOSL2 2355 FOS-like antigen 2



Activity profile for motif FOSL2.p2.

activity profile for motif FOSL2.p2


Sorted Z-values histogram for motif FOSL2.p2

Sorted Z-values for motif FOSL2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOSL2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_72958207 2.720 NM_001113496
SEPT9
septin 9
chr17_+_72958330 2.469 SEPT9
septin 9
chr20_+_42776888 2.353 WISP2
WNT1 inducible signaling pathway protein 2
chr10_+_134751398 1.768 NM_001083909
GPR123
G protein-coupled receptor 123
chr3_-_188936941 1.685 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr16_+_51690564 1.651 CHD9
chromodomain helicase DNA binding protein 9
chr16_+_88515917 1.489 NM_001197181
TUBB3
tubulin, beta 3
chr17_-_37022465 1.394 NM_005557
KRT16
keratin 16
chr16_+_84204424 1.394 NM_014615
KIAA0182
KIAA0182
chr13_+_112746908 1.388 MCF2L
MCF.2 cell line derived transforming sequence-like
chr7_+_30927439 1.353 NM_001185060
NM_001185061
NM_001185062
AQP1


aquaporin 1 (Colton blood group)


chr3_+_134976965 1.352 TF
transferrin
chr16_+_65868913 1.303 NM_015432
PLEKHG4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr20_+_42777298 1.255 NM_003881
WISP2
WNT1 inducible signaling pathway protein 2
chr16_+_82544327 1.214 NM_182981
OSGIN1
oxidative stress induced growth inhibitor 1
chr1_-_7998265 1.161 ERRFI1
ERBB receptor feedback inhibitor 1
chr9_+_139255559 1.048 TUBB2C
tubulin, beta 2C
chr17_+_41424665 1.046 MAPT
microtubule-associated protein tau
chr16_+_1246273 1.038 NM_012217
TPSD1
tryptase delta 1
chr19_-_62028185 1.030 NM_001146186
PEG3
paternally expressed 3
chr16_+_22216223 1.024 NM_018119
POLR3E
polymerase (RNA) III (DNA directed) polypeptide E (80kD)
chr5_+_177473071 1.007 NM_015111
N4BP3
NEDD4 binding protein 3
chr3_-_48607596 0.986 NM_000094
COL7A1
collagen, type VII, alpha 1
chr20_+_42777419 0.967 WISP2
WNT1 inducible signaling pathway protein 2
chr20_-_1257782 0.960 SDCBP2
syndecan binding protein (syntenin) 2
chr20_+_42463350 0.935 HNF4A
hepatocyte nuclear factor 4, alpha
chr5_-_54317102 0.934 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr9_+_139255519 0.929 NM_006088
TUBB2C
tubulin, beta 2C
chr2_+_87536106 0.928 NCRNA00152
non-protein coding RNA 152
chr2_+_87536174 0.923 NCRNA00152
non-protein coding RNA 152
chr8_+_10567556 0.918 NM_001040032
C8orf74
chromosome 8 open reading frame 74
chr20_-_1257809 0.918 NM_080489
SDCBP2
syndecan binding protein (syntenin) 2
chr2_-_219566364 0.904 NM_005209
NM_057093
NM_057094
CRYBA2


crystallin, beta A2


chr20_+_34206070 0.899 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr20_+_42463279 0.892 NM_000457
NM_178849
NM_178850
HNF4A


hepatocyte nuclear factor 4, alpha


chr19_-_3920736 0.877 NM_001348
DAPK3
death-associated protein kinase 3
chr19_-_6621598 0.871 NM_003807
NM_172014
TNFSF14

tumor necrosis factor (ligand) superfamily, member 14

chr17_+_72827227 0.859 SEPT9
septin 9
chr16_-_62573 0.857 NM_022450
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr2_+_119905812 0.838 NM_183240
TMEM37
transmembrane protein 37
chr20_+_42463387 0.830 HNF4A
hepatocyte nuclear factor 4, alpha
chr22_+_21370394 0.829 IGL@
immunoglobulin lambda locus
chr14_-_93919305 0.826 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr7_-_5533621 0.800 ACTB
actin, beta
chr2_-_162808123 0.797 NM_004460
FAP
fibroblast activation protein, alpha
chr2_-_215967442 0.793 FN1
fibronectin 1
chr17_+_21131940 0.787 NM_002756
MAP2K3
mitogen-activated protein kinase kinase 3
chr16_+_68765428 0.772 NM_173619
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr12_-_68369322 0.771 NM_152439
BEST3
bestrophin 3
chr19_+_54068300 0.769 PPP1R15A
protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr20_+_44070946 0.752 NM_004994
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr2_+_218833982 0.746 NM_001077191
NM_001077194
NM_170699
GPBAR1


G protein-coupled bile acid receptor 1


chr20_+_42463419 0.743 HNF4A
hepatocyte nuclear factor 4, alpha
chr16_+_29984621 0.738 ALDOA
aldolase A, fructose-bisphosphate
chr7_-_128330615 0.719 KCP
kielin/chordin-like protein
chr7_+_26298136 0.715 SNX10
sorting nexin 10
chr3_+_153074118 0.711 NM_033050
SUCNR1
succinate receptor 1
chr19_-_6621078 0.696 TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr2_-_89223666 0.694 IGKC
IGK@
immunoglobulin kappa constant
immunoglobulin kappa locus
chr16_+_29984591 0.675 ALDOA
aldolase A, fructose-bisphosphate
chr20_+_61394982 0.670 NM_020882
COL20A1
collagen, type XX, alpha 1
chr14_-_22658078 0.661 NM_001805
CEBPE
CCAAT/enhancer binding protein (C/EBP), epsilon
chr19_+_11061037 0.661 NM_000527
NM_001195798
NM_001195799
NM_001195800
NM_001195802
NM_001195803
LDLR





low density lipoprotein receptor





chr16_+_29984611 0.656 ALDOA
aldolase A, fructose-bisphosphate
chr8_-_42742729 0.654 NM_004198
CHRNA6
cholinergic receptor, nicotinic, alpha 6
chr3_-_195571748 0.652 NM_001135057
NM_130830
LRRC15

leucine rich repeat containing 15

chr1_-_45045543 0.649 NM_001013632
TCTEX1D4
Tctex1 domain containing 4
chr1_-_180624494 0.646 GLUL
glutamate-ammonia ligase
chr11_+_696607 0.645 EPS8L2
EPS8-like 2
chr2_-_40510923 0.640 NM_001112800
NM_001112801
NM_021097
SLC8A1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr1_-_207891264 0.640 NM_001017402
LAMB3
laminin, beta 3
chr11_-_8695974 0.639 ST5
suppression of tumorigenicity 5
chr16_+_29984647 0.636 ALDOA
aldolase A, fructose-bisphosphate
chr2_-_241484245 0.633 NM_001085437
C2orf54
chromosome 2 open reading frame 54
chr4_+_169250281 0.627 NM_007193
ANXA10
annexin A10
chr11_+_12265022 0.623 NM_032867
MICALCL
MICAL C-terminal like
chr2_+_97696462 0.619 NM_001079
ZAP70
zeta-chain (TCR) associated protein kinase 70kDa
chr2_+_169631777 0.619 NM_199204
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr2_-_144991556 0.619 ZEB2
zinc finger E-box binding homeobox 2
chr17_-_45617899 0.609 COL1A1
collagen, type I, alpha 1
chr12_+_50731457 0.607 NM_002135
NM_173157
NR4A1

nuclear receptor subfamily 4, group A, member 1

chr13_-_98757634 0.578 NM_004951
GPR183
G protein-coupled receptor 183
chr2_+_219991342 0.573 NM_001927
DES
desmin
chr16_+_29984544 0.573 NM_184041
ALDOA
aldolase A, fructose-bisphosphate
chr2_+_89849009 0.573


chr22_+_21340757 0.572


chr8_-_143848225 0.572 NM_177458
LYNX1
Ly6/neurotoxin 1
chr9_+_676640 0.570


chr6_-_41781655 0.565 TFEB
transcription factor EB
chr22_+_21484240 0.557


chr12_-_10173947 0.553 NM_022570
NM_197947
NM_197948
NM_197949
NM_197950
NM_197954
CLEC7A





C-type lectin domain family 7, member A





chr2_-_1905508 0.550 MYT1L
myelin transcription factor 1-like
chr2_+_27358800 0.543 NM_032546
NM_187841
TRIM54

tripartite motif containing 54

chr1_+_17719405 0.541 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr11_+_696103 0.541 NM_022772
EPS8L2
EPS8-like 2
chr17_+_72827185 0.539 NM_006640
SEPT9
septin 9
chr14_-_104507862 0.529 AHNAK2
AHNAK nucleoprotein 2
chr22_-_48437081 0.528 C22orf34
chromosome 22 open reading frame 34
chr21_+_46367216 0.521 COL6A2
collagen, type VI, alpha 2
chr8_-_103735194 0.517 NM_001032282
KLF10
Kruppel-like factor 10
chr22_+_38246509 0.514 NM_001675
NM_182810
ATF4

activating transcription factor 4 (tax-responsive enhancer element B67)

chr20_-_35586366 0.508 NM_001167823
BLCAP
bladder cancer associated protein
chr17_-_7962859 0.507 NM_001165960
ALOXE3
arachidonate lipoxygenase 3
chr6_-_169392771 0.506


chr22_-_43040063 0.502 NM_001099294
KIAA1644
KIAA1644
chr7_+_101978777 0.502 NM_001166339
NM_001031618
SPDYE2L
SPDYE2
WBSCR19-like protein 3
speedy homolog E2 (Xenopus laevis)
chr16_+_31274030 0.500 ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr16_+_80301165 0.499 CMIP
c-Maf-inducing protein
chr16_+_48857962 0.496 ADCY7
adenylate cyclase 7
chr8_+_22900863 0.486 NM_001160036
RHOBTB2
Rho-related BTB domain containing 2
chr7_+_23252909 0.486 GPNMB
glycoprotein (transmembrane) nmb
chr2_-_144991386 0.482 ZEB2
zinc finger E-box binding homeobox 2
chr12_-_9913199 0.481 CLEC2B
C-type lectin domain family 2, member B
chr10_+_24795465 0.481 KIAA1217
KIAA1217
chr9_+_138866618 0.473 NM_206920
MAMDC4
MAM domain containing 4
chr1_-_93030538 0.469 NM_005665
EVI5
ecotropic viral integration site 5
chr15_+_65205107 0.468 NM_001145102
SMAD3
SMAD family member 3
chr16_+_31274020 0.466 ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr2_+_220200530 0.466 NM_005070
NM_201574
SLC4A3

solute carrier family 4, anion exchanger, member 3

chr17_+_7196151 0.464 KCTD11
potassium channel tetramerisation domain containing 11
chr16_+_27346079 0.463 NM_021798
IL21R
interleukin 21 receptor
chr9_+_139255563 0.462 TUBB2C
tubulin, beta 2C
chr4_+_6746466 0.461 NM_005980
S100P
S100 calcium binding protein P
chr7_+_150319076 0.460 NM_000603
NOS3
nitric oxide synthase 3 (endothelial cell)
chr2_+_68726457 0.460 NM_138964
PROKR1
prokineticin receptor 1
chr8_-_11748330 0.459


chr10_+_24795446 0.458 KIAA1217
KIAA1217
chr1_-_180624380 0.457 GLUL
glutamate-ammonia ligase
chr12_-_15005761 0.446 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr17_+_71893014 0.445 SPHK1
sphingosine kinase 1
chr2_-_89400935 0.443 IGKC
immunoglobulin kappa constant
chr1_-_17180659 0.443 NM_001135247
NM_017459
MFAP2

microfibrillar-associated protein 2

chr6_-_44341222 0.434 NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr3_-_122862391 0.432 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr12_+_6514645 0.431 GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr16_+_31312097 0.429 NM_005353
ITGAD
integrin, alpha D
chr9_-_16717887 0.426 BNC2
basonuclin 2
chr6_-_44341296 0.425 NM_004556
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr6_-_32121784 0.424 NM_032470
TNXB
tenascin XB
chr5_-_141041933 0.424 ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr14_+_22059174 0.424


chr5_-_150501393 0.422 NM_001193544
ANXA6
annexin A6
chr16_+_66121040 0.421 NM_001193523
FAM65A
family with sequence similarity 65, member A
chr15_+_65245546 0.419 NM_001145104
SMAD3
SMAD family member 3
chr2_-_231498184 0.418 NM_005683
GPR55
G protein-coupled receptor 55
chr19_+_2427122 0.417 NM_015675
GADD45B
growth arrest and DNA-damage-inducible, beta
chr10_+_111755715 0.416 NM_019903
ADD3
adducin 3 (gamma)
chr16_+_87047159 0.415 ZFPM1
zinc finger protein, multitype 1
chr3_-_15814678 0.414 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr20_+_35445350 0.412 SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr10_-_21847126 0.411


chr3_+_52325374 0.411 NM_015512
DNAH1
dynein, axonemal, heavy chain 1
chr16_+_31273969 0.409 NM_000887
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr19_+_43971689 0.407 NM_001042507
LGALS7B
lectin, galactoside-binding, soluble, 7B
chr2_-_87102453 0.407 NM_002665
NM_001032392
PLGLB2
PLGLB1
plasminogen-like B2
plasminogen-like B1
chr3_-_122862447 0.404 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr14_+_22059212 0.401


chr7_+_129720209 0.400 NM_001163446
NM_016352
CPA4

carboxypeptidase A4

chr17_+_19255083 0.400 NM_007148
RNF112
ring finger protein 112
chr16_-_1220163 0.399 NM_024164
TPSB2
TPSAB1
tryptase beta 2 (gene/pseudogene)
tryptase alpha/beta 1
chr16_+_49139694 0.398 NM_033119
NKD1
naked cuticle homolog 1 (Drosophila)
chr1_-_202432165 0.396 NM_002256
KISS1
KiSS-1 metastasis-suppressor
chr7_+_23252911 0.396 GPNMB
glycoprotein (transmembrane) nmb
chr16_+_65869558 0.396 NM_001129727
PLEKHG4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr5_-_149473127 0.394 NM_005211
CSF1R
colony stimulating factor 1 receptor
chr2_+_86521999 0.394 NM_001146688
KDM3A
lysine (K)-specific demethylase 3A
chr5_-_141041982 0.391 NM_022481
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr20_+_43943254 0.391 NM_080603
ZSWIM1
zinc finger, SWIM-type containing 1
chr17_+_23824784 0.390 NM_001145975
NM_001145976
NM_003984
SLC13A2


solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2


chr19_+_1199548 0.387 NM_177401
MIDN
midnolin
chr17_+_71292275 0.386 NM_001080419
UNK
unkempt homolog (Drosophila)
chr19_+_40511909 0.386 NM_001185099
NM_001185100
NM_001185101
NM_001771
CD22



CD22 molecule



chr12_-_51629874 0.385 KRT8
keratin 8
chr22_+_43451600 0.384 PRR5
proline rich 5 (renal)
chr17_+_7063873 0.381 NM_000018
NM_001033859
ACADVL

acyl-CoA dehydrogenase, very long chain

chr10_+_63478974 0.381 ARID5B
AT rich interactive domain 5B (MRF1-like)
chr9_+_131291144 0.379


chr19_-_18246166 0.379 NM_001145304
NM_001145305
NM_025249
KIAA1683


KIAA1683


chr17_+_77910411 0.378 NM_207459
TEX19
testis expressed 19
chr11_-_72057755 0.377 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chrX_-_65752570 0.377 NM_021783
EDA2R
ectodysplasin A2 receptor
chr2_+_151922350 0.375 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr11_-_64133908 0.375


chr12_+_54361685 0.375 METTL7B
methyltransferase like 7B
chr7_+_23252926 0.374 GPNMB
glycoprotein (transmembrane) nmb
chr19_-_51820133 0.374 NM_000960
PTGIR
prostaglandin I2 (prostacyclin) receptor (IP)
chr4_-_122304925 0.371 NM_024873
TNIP3
TNFAIP3 interacting protein 3
chr7_+_23252915 0.371 GPNMB
glycoprotein (transmembrane) nmb
chr11_+_44026106 0.370 NM_001031854
ACCSL
1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)-like
chr19_+_54068373 0.367 PPP1R15A
protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr15_-_88023576 0.366 NM_001145311
NM_002666
PLIN1

perilipin 1

chr6_-_28429950 0.365 NM_145909
ZNF323
zinc finger protein 323
chr4_-_5879488 0.362 CRMP1
collapsin response mediator protein 1
chr2_-_85494639 0.361 CAPG
capping protein (actin filament), gelsolin-like
chr12_+_110689094 0.359 ALDH2
aldehyde dehydrogenase 2 family (mitochondrial)
chr2_-_85749374 0.358 NM_000542
NM_198843
SFTPB

surfactant protein B

chr17_+_77261440 0.357 HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr12_+_54361596 0.357 NM_152637
METTL7B
methyltransferase like 7B
chr19_+_1223475 0.357 CIRBP
cold inducible RNA binding protein
chr1_+_201363458 0.356 NM_000674
NM_001048230
ADORA1

adenosine A1 receptor


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.93 1.10e-03 GO:0001775 cell activation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.47 2.00e-02 GO:0044421 extracellular region part
1.36 3.40e-02 GO:0005856 cytoskeleton
11.38 4.37e-02 GO:0034992 microtubule organizing center attachment site
11.38 4.37e-02 GO:0034993 SUN-KASH complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.86 1.67e-02 GO:0030246 carbohydrate binding