Motif ID: FOXA2.p3

Z-value: 1.670


Transcription factors associated with FOXA2.p3:

Gene SymbolEntrez IDGene Name
FOXA2 3170 forkhead box A2



Activity profile for motif FOXA2.p3.

activity profile for motif FOXA2.p3


Sorted Z-values histogram for motif FOXA2.p3

Sorted Z-values for motif FOXA2.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXA2.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_23204887 3.734 NM_000462
UBE3A
ubiquitin protein ligase E3A
chr2_-_55053398 2.373


chr4_+_69716298 2.267 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr17_+_36642240 1.738 NM_031962
KRTAP9-9
KRTAP9-3
keratin associated protein 9-9
keratin associated protein 9-3
chr12_+_21417068 1.651 NM_000415
IAPP
islet amyloid polypeptide
chr10_+_63478974 1.594 ARID5B
AT rich interactive domain 5B (MRF1-like)
chr2_-_215967442 1.584 FN1
fibronectin 1
chr2_-_21079145 1.496 APOB
apolipoprotein B (including Ag(x) antigen)
chr20_+_9406460 1.496 PLCB4
phospholipase C, beta 4
chr8_-_25338472 1.472 NM_000825
NM_001083111
GNRH1

gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)

chr5_+_147754467 1.464 FBXO38
F-box protein 38
chr4_-_70115037 1.418 NM_001073
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr1_-_103269356 1.417 COL11A1
collagen, type XI, alpha 1
chr2_-_21084911 1.395 APOB
apolipoprotein B (including Ag(x) antigen)
chr14_+_54238581 1.350 SAMD4A
sterile alpha motif domain containing 4A
chr2_-_210726539 1.350 C2orf67
chromosome 2 open reading frame 67
chr3_-_121065112 1.348


chr1_-_156784518 1.305 NM_001005189
OR6Y1
olfactory receptor, family 6, subfamily Y, member 1
chr17_+_36665161 1.269 NM_030975
KRTAP9-9
keratin associated protein 9-9
chr6_+_64414389 1.234 NM_015153
PHF3
PHD finger protein 3
chr6_+_64403668 1.233 PHF3
PHD finger protein 3
chr6_+_131190237 1.232 NM_001195597
LOC285733
hypothetical LOC285733
chr4_+_169250281 1.220 NM_007193
ANXA10
annexin A10
chr3_-_115380539 1.204 NM_000796
NM_033663
DRD3

dopamine receptor D3

chr2_+_182464910 1.203 SSFA2
sperm specific antigen 2
chr8_+_87947788 1.194 NM_173538
CNBD1
cyclic nucleotide binding domain containing 1
chr1_+_74473672 1.191 NM_015978
TNNI3K
TNNI3 interacting kinase
chr7_+_134226727 1.186 CALD1
caldesmon 1
chr2_-_21084077 1.184 APOB
apolipoprotein B (including Ag(x) antigen)
chr20_+_31219543 1.168 NM_080574
C20orf70
chromosome 20 open reading frame 70
chr12_-_10479810 1.165 NM_002260
KLRC2
KLRC3
killer cell lectin-like receptor subfamily C, member 2
killer cell lectin-like receptor subfamily C, member 3
chr5_+_132237253 1.152 NM_052971
LEAP2
liver expressed antimicrobial peptide 2
chr11_-_26700121 1.149 NM_178498
SLC5A12
solute carrier family 5 (sodium/glucose cotransporter), member 12
chr5_+_10406980 1.128


chr11_+_55776251 1.128 NM_001004747
OR5T3
olfactory receptor, family 5, subfamily T, member 3
chr7_+_106596641 1.124 NM_012257
HBP1
HMG-box transcription factor 1
chr20_+_56912146 1.120 GNAS
GNAS complex locus
chr5_+_135496421 1.117 NM_001001419
NM_001001420
NM_005903
SMAD5


SMAD family member 5


chr11_-_121492010 1.086 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr3_+_150028130 1.061 NM_001871
CPB1
carboxypeptidase B1 (tissue)
chr1_+_81544432 1.041 LPHN2
latrophilin 2
chr3_+_70131572 1.030


chr12_-_642786 0.982 NM_016533
NINJ2
ninjurin 2
chr20_-_41788975 0.957 NM_001008901
NM_176791
GTSF1L

gametocyte specific factor 1-like

chr2_+_196229715 0.947 NM_001127257
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr3_+_139200347 0.938 NM_001002026
CLDN18
claudin 18
chr11_-_107969554 0.936 NM_015065
EXPH5
exophilin 5
chr2_+_214984705 0.933 NM_001080500
VWC2L
von Willebrand factor C domain containing protein 2-like
chr4_+_70896236 0.932 NM_001009181
NM_003154
STATH

statherin

chr5_-_39238818 0.929 FYB
FYN binding protein
chr9_-_21472311 0.923 NM_176891
IFNE
interferon, epsilon
chr12_-_10464308 0.920 NM_002261
NM_007333
KLRC3

killer cell lectin-like receptor subfamily C, member 3

chr5_+_135496437 0.916 SMAD5
SMAD family member 5
chr2_+_196230096 0.912 NM_020342
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr13_-_98757634 0.894 NM_004951
GPR183
G protein-coupled receptor 183
chr11_-_4555625 0.894 NM_144663
C11orf40
chromosome 11 open reading frame 40
chr8_+_17866373 0.882 PCM1
pericentriolar material 1
chr2_-_21081694 0.861 APOB
apolipoprotein B (including Ag(x) antigen)
chr9_-_14900992 0.856 NM_144966
FREM1
FRAS1 related extracellular matrix 1
chr8_+_17874128 0.851 PCM1
pericentriolar material 1
chr14_+_20226762 0.848 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr3_+_176059763 0.844 NM_207015
NAALADL2
N-acetylated alpha-linked acidic dipeptidase-like 2
chr16_+_14187965 0.842 MKL2
MKL/myocardin-like 2
chr10_+_104525877 0.840 NM_017787
C10orf26
chromosome 10 open reading frame 26
chr2_-_20390601 0.835 NM_015317
PUM2
pumilio homolog 2 (Drosophila)
chr20_+_29492071 0.826 NM_153324
DEFB123
defensin, beta 123
chr4_+_86615275 0.825 NM_001025616
ARHGAP24
Rho GTPase activating protein 24
chr7_+_116151411 0.824 MET
met proto-oncogene (hepatocyte growth factor receptor)
chr15_+_46271158 0.822 NM_001145668
CTXN2
SLC12A1
cortexin 2
solute carrier family 12 (sodium/potassium/chloride transporters), member 1
chr4_-_164754106 0.811 NM_017923
MARCH1
membrane-associated ring finger (C3HC4) 1
chr14_-_19553191 0.809 NM_001004712
OR4K14
olfactory receptor, family 4, subfamily K, member 14
chr5_+_27508139 0.794 LOC643401
hypothetical protein LOC643401
chr17_-_3142625 0.774 NM_002550
OR3A1
olfactory receptor, family 3, subfamily A, member 1
chr2_-_69033515 0.771 NM_182536
GKN2
gastrokine 2
chr16_-_87570716 0.759 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr1_+_90233238 0.757 NM_182975
NM_182976
ZNF326

zinc finger protein 326

chr3_-_99795074 0.749 NM_000097
CPOX
coproporphyrinogen oxidase
chr1_-_150564302 0.740 NM_002016
FLG
filaggrin
chr11_-_9182356 0.732 DENND5A
DENN/MADD domain containing 5A
chr9_+_128764324 0.731 NM_001190728
RALGPS1
Ral GEF with PH domain and SH3 binding motif 1
chr2_+_234191029 0.726 NM_019076
UGT1A8
UDP glucuronosyltransferase 1 family, polypeptide A8
chr4_-_104160291 0.725 NM_001100874
NM_139173
NHEDC1

Na+/H+ exchanger domain containing 1

chr12_-_78831821 0.722 NM_001143886
PPP1R12A
protein phosphatase 1, regulatory (inhibitor) subunit 12A
chr3_-_191650291 0.721 NM_207316
TMEM207
transmembrane protein 207
chr20_+_29309127 0.715 NM_001037730
DEFB115
defensin, beta 115
chr1_-_229058404 0.711 NM_001136495
C1orf198
chromosome 1 open reading frame 198
chr6_-_90081655 0.710 NM_002043
GABRR2
gamma-aminobutyric acid (GABA) receptor, rho 2
chr12_+_123339662 0.703 NM_181709
FAM101A
family with sequence similarity 101, member A
chr4_-_153523113 0.701 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr5_-_135729062 0.700 NM_001167576
NM_001167577
NM_020389
TRPC7


transient receptor potential cation channel, subfamily C, member 7


chr15_+_22781292 0.697 PAR5
Prader-Willi/Angelman syndrome-5
chr2_-_65013070 0.691 LOC400958
hypothetical LOC400958
chr8_-_93099040 0.690 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_-_93866554 0.684 NM_005590
NM_005591
MRE11A

MRE11 meiotic recombination 11 homolog A (S. cerevisiae)

chr7_-_81237162 0.683 NM_000601
NM_001010931
NM_001010932
NM_001010933
NM_001010934
HGF




hepatocyte growth factor (hepapoietin A; scatter factor)




chr4_+_70180805 0.681 NM_053039
UGT2B28
UDP glucuronosyltransferase 2 family, polypeptide B28
chr1_+_86662356 0.680 NM_006536
CLCA2
chloride channel accessory 2
chr6_+_127940011 0.678 NM_001010905
C6orf58
chromosome 6 open reading frame 58
chr3_+_99334230 0.677 NM_001005338
OR5H1
olfactory receptor, family 5, subfamily H, member 1
chr5_+_52892217 0.677 NM_002495
NDUFS4
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
chr4_-_140443061 0.677 NM_001184987
NM_001184988
NM_001184989
NM_001184990
NDUFC1



NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa



chr3_+_50687675 0.674 NM_004947
DOCK3
dedicator of cytokinesis 3
chr4_-_164614335 0.673 NM_032136
TKTL2
transketolase-like 2
chr3_+_179759181 0.672 NM_005832
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr2_+_170149348 0.670 PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr18_+_64616296 0.670 NM_024781
CCDC102B
coiled-coil domain containing 102B
chr4_+_157044296 0.668 NM_005651
TDO2
tryptophan 2,3-dioxygenase
chr14_+_36200815 0.667 PAX9
paired box 9
chr10_-_49152918 0.665 NM_001018071
FRMPD2
FERM and PDZ domain containing 2
chr7_+_90177082 0.663 CDK14
cyclin-dependent kinase 14
chr6_+_7052985 0.659 NM_001003698
NM_001003699
NM_001003700
RREB1


ras responsive element binding protein 1


chr10_+_124729899 0.658 PSTK
phosphoseryl-tRNA kinase
chr3_-_114176401 0.656 NM_138806
NM_138939
NM_138940
NM_170780
CD200R1



CD200 receptor 1



chr14_-_105644300 0.647 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr12_-_11066436 0.641 NM_176888
TAS2R19
taste receptor, type 2, member 19
chr9_-_34700062 0.641 NM_002989
CCL21
chemokine (C-C motif) ligand 21
chr11_+_55842358 0.633 NM_001005202
OR8K3
olfactory receptor, family 8, subfamily K, member 3
chr9_+_6403321 0.632 UHRF2
ubiquitin-like with PHD and ring finger domains 2
chr6_-_127822227 0.632 NM_014702
KIAA0408
KIAA0408
chr1_-_150599105 0.631 NM_001014342
FLG2
filaggrin family member 2
chr18_+_28023984 0.627 NM_005925
MEP1B
meprin A, beta
chr6_+_7053183 0.626 RREB1
ras responsive element binding protein 1
chr3_+_173951163 0.624 ECT2
epithelial cell transforming sequence 2 oncogene
chr12_+_63090008 0.622 XPOT
exportin, tRNA (nuclear export receptor for tRNAs)
chr12_+_99391870 0.619 NR1H4
nuclear receptor subfamily 1, group H, member 4
chr11_-_27637771 0.619 NM_001143816
NM_170735
BDNF

brain-derived neurotrophic factor

chr12_-_11041740 0.615 NM_176889
TAS2R20
taste receptor, type 2, member 20
chr13_+_75232797 0.615 NM_015842
LMO7
LIM domain 7
chr14_+_55654900 0.614 PELI2
pellino homolog 2 (Drosophila)
chr6_+_154373323 0.605 NM_001145279
NM_001145280
NM_001145281
OPRM1


opioid receptor, mu 1


chr6_+_55147029 0.602 NM_001526
HCRTR2
hypocretin (orexin) receptor 2
chr5_+_52892229 0.601 NDUFS4
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
chr4_+_69465107 0.601 NM_014058
TMPRSS11E
transmembrane protease, serine 11E
chr5_+_81636921 0.600 NM_001017971
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr3_-_87408301 0.598 NM_000306
NM_001122757
POU1F1

POU class 1 homeobox 1

chr6_-_47030492 0.595 NM_015234
GPR116
G protein-coupled receptor 116
chr3_-_194755281 0.593 NM_032279
ATP13A4
ATPase type 13A4
chr2_+_191009265 0.593 MFSD6
major facilitator superfamily domain containing 6
chr14_+_36200867 0.593 PAX9
paired box 9
chr9_+_6403183 0.582 UHRF2
ubiquitin-like with PHD and ring finger domains 2
chr18_+_27425727 0.582 NM_000371
TTR
transthyretin
chrX_+_24077782 0.579 ZFX
zinc finger protein, X-linked
chr7_-_132371208 0.578 EEF1G
eukaryotic translation elongation factor 1 gamma
chr2_+_183316574 0.577 DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr14_+_18447521 0.573 NM_001013354
OR11H12
olfactory receptor, family 11, subfamily H, member 12
chrX_+_24077649 0.571 NM_001178086
NM_001178095
NM_001178084
NM_001178085
NM_003410
ZFX




zinc finger protein, X-linked




chr4_+_35959638 0.571 NM_001136536
DTHD1
death domain containing 1
chr5_-_58607673 0.570 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr8_+_21833111 0.567 NM_015024
XPO7
exportin 7
chr1_+_69998445 0.567 NM_020794
LRRC7
leucine rich repeat containing 7
chr17_+_64922420 0.567 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr10_+_124729545 0.565 NM_153336
PSTK
phosphoseryl-tRNA kinase
chr5_+_147775652 0.565 FBXO38
F-box protein 38
chr5_-_13997588 0.561 NM_001369
DNAH5
dynein, axonemal, heavy chain 5
chr3_+_173954940 0.558 NM_018098
ECT2
epithelial cell transforming sequence 2 oncogene
chr4_+_111616630 0.556 NM_001977
ENPEP
glutamyl aminopeptidase (aminopeptidase A)
chr7_+_111879348 0.555 NM_001197079
IFRD1
interferon-related developmental regulator 1
chr4_+_71054492 0.554 NM_214711
C4orf40
chromosome 4 open reading frame 40
chr7_+_80069439 0.550 NM_001001547
CD36
CD36 molecule (thrombospondin receptor)
chr2_+_190248955 0.547 NM_144708
ANKAR
ankyrin and armadillo repeat containing
chr5_-_43326922 0.547 HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr3_-_150569574 0.544 TM4SF1
transmembrane 4 L six family member 1
chr7_+_134226690 0.542 NM_033139
NM_033140
CALD1

caldesmon 1

chr6_+_132933153 0.540 NM_175067
TAAR6
trace amine associated receptor 6
chr2_-_99412694 0.537 REV1
REV1 homolog (S. cerevisiae)
chr17_-_46296376 0.537 NM_005749
TOB1
transducer of ERBB2, 1
chr8_+_21833162 0.536 XPO7
exportin 7
chr20_-_52120421 0.535 BCAS1
breast carcinoma amplified sequence 1
chr2_-_71307705 0.534 NM_020459
PAIP2B
poly(A) binding protein interacting protein 2B
chr12_-_14929991 0.532 NM_000900
NM_001190839
MGP

matrix Gla protein

chr13_-_47916803 0.528 NM_005767
LPAR6
lysophosphatidic acid receptor 6
chr14_+_64041170 0.525 ZBTB1
zinc finger and BTB domain containing 1
chr11_-_55128424 0.525 NM_001004700
OR4C11
olfactory receptor, family 4, subfamily C, member 11
chr10_-_129581192 0.523 NM_152311
CLRN3
clarin 3
chr3_+_35696119 0.522 NM_001025068
NM_001025069
ARPP21

cAMP-regulated phosphoprotein, 21kDa

chr14_-_24173205 0.520 NM_004131
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr1_+_246578699 0.519 NM_001001918
OR14C36
olfactory receptor, family 14, subfamily C, member 36
chr3_+_186563529 0.515 NM_004721
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr6_+_118976134 0.515 NM_002667
PLN
phospholamban
chr12_+_6745947 0.514 PTMS
parathymosin
chrX_+_123307812 0.514 NM_001114937
NM_002351
SH2D1A

SH2 domain containing 1A

chr21_-_38955487 0.511 NM_001136154
NM_004449
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr7_+_134483305 0.511 NM_018295
TMEM140
transmembrane protein 140
chr2_+_211129567 0.504 NM_001875
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr11_+_22646229 0.499 NM_177553
GAS2
growth arrest-specific 2
chr2_+_170149092 0.495 NM_004792
PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr3_+_23904086 0.493 UBE2E1
ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)
chr3_+_145174856 0.492 NM_001134470
C3orf58
chromosome 3 open reading frame 58
chr7_+_94377145 0.492 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory (inhibitor) subunit 9A


chr10_-_54201400 0.492 NM_000242
MBL2
mannose-binding lectin (protein C) 2, soluble
chr10_+_90336489 0.490 NM_001010939
LIPJ
lipase, family member J
chr6_-_50045296 0.490 NM_001037729
DEFB113
defensin, beta 113
chr3_+_99370233 0.487 NM_001005515
OR5H15
olfactory receptor, family 5, subfamily H, member 15
chr11_-_5178505 0.485 NM_001004760
OR51V1
olfactory receptor, family 51, subfamily V, member 1
chr17_-_36276987 0.481 NM_000223
KRT12
keratin 12
chr10_-_75005421 0.480 NM_152586
USP54
ubiquitin specific peptidase 54
chr4_-_152368492 0.479 SH3D19
SH3 domain containing 19
chr2_-_36929520 0.476 STRN
striatin, calmodulin binding protein
chr14_+_87560646 0.475 LOC283587
hypothetical protein LOC283587
chr1_-_214663360 0.474 NM_007123
NM_206933
USH2A

Usher syndrome 2A (autosomal recessive, mild)


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.15 8.10e-19 GO:0007606 sensory perception of chemical stimulus
3.11 4.37e-16 GO:0007608 sensory perception of smell
2.29 2.81e-13 GO:0007600 sensory perception
1.82 1.63e-09 GO:0050877 neurological system process
1.69 8.80e-09 GO:0003008 system process
1.26 8.52e-05 GO:0032501 multicellular organismal process
1.23 1.44e-04 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.35 6.48e-08 GO:0005886 plasma membrane
1.35 9.85e-08 GO:0071944 cell periphery
1.19 1.73e-05 GO:0016020 membrane
1.21 9.78e-05 GO:0044425 membrane part
1.23 1.67e-04 GO:0016021 integral to membrane
1.22 2.83e-04 GO:0031224 intrinsic to membrane
1.38 1.85e-03 GO:0005576 extracellular region

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.22 2.27e-17 GO:0004984 olfactory receptor activity
2.31 6.88e-15 GO:0004930 G-protein coupled receptor activity
1.87 8.31e-11 GO:0004888 transmembrane receptor activity
1.72 1.53e-10 GO:0004872 receptor activity
1.61 2.21e-09 GO:0004871 signal transducer activity
1.61 2.21e-09 GO:0060089 molecular transducer activity