Motif ID: FOXP3.p2

Z-value: 1.286


Transcription factors associated with FOXP3.p2:

Gene SymbolEntrez IDGene Name
FOXP3 50943 forkhead box P3



Activity profile for motif FOXP3.p2.

activity profile for motif FOXP3.p2


Sorted Z-values histogram for motif FOXP3.p2

Sorted Z-values for motif FOXP3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXP3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_17563186 2.877 NM_001099218
RAD51AP2
RAD51 associated protein 2
chr11_-_51269023 1.888 NM_001005272
OR4A5
olfactory receptor, family 4, subfamily A, member 5
chr10_-_72215116 1.672 NM_152710
C10orf27
chromosome 10 open reading frame 27
chr14_+_19655405 1.600 NM_001004715
OR4K17
olfactory receptor, family 4, subfamily K, member 17
chr12_-_10479810 1.458 NM_002260
KLRC2
KLRC3
killer cell lectin-like receptor subfamily C, member 2
killer cell lectin-like receptor subfamily C, member 3
chr14_-_20969706 1.327 NM_001170629
CHD8
chromodomain helicase DNA binding protein 8
chr11_+_54867202 1.304 NM_001005274
OR4A16
olfactory receptor, family 4, subfamily A, member 16
chr7_+_28441758 1.191 NM_004904
CREB5
cAMP responsive element binding protein 5
chr12_+_79362256 1.158 NM_001145026
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chrX_-_8099307 1.151 NM_016378
VCX2
variable charge, X-linked 2
chr3_-_57288019 1.118 NM_130387
ASB14
ankyrin repeat and SOCS box containing 14
chr19_-_49523747 1.116 ZFP112
zinc finger protein 112 homolog (mouse)
chr10_-_37931864 1.056 NM_001190489
MTRNR2L7
MT-RNR2-like 7
chrX_+_105298953 1.055 NM_001171020
NM_152423
MUM1L1

melanoma associated antigen (mutated) 1-like 1

chr15_+_19869841 0.998 NM_001004719
OR4M2
olfactory receptor, family 4, subfamily M, member 2
chr4_+_70180805 0.986 NM_053039
UGT2B28
UDP glucuronosyltransferase 2 family, polypeptide B28
chr6_-_11887265 0.965 NM_001143948
NM_032744
C6orf105

chromosome 6 open reading frame 105

chr11_+_55799604 0.939 NM_001004745
OR5T1
olfactory receptor, family 5, subfamily T, member 1
chr4_+_114433551 0.812 ANK2
ankyrin 2, neuronal
chr5_+_140194152 0.788 NM_018910
NM_031852
PCDHA7

protocadherin alpha 7

chr1_-_151296611 0.759 NM_005988
SPRR2A
small proline-rich protein 2A
chr17_+_49255237 0.755 NM_032559
KIF2B
kinesin family member 2B
chr4_-_123596921 0.708 NM_000586
IL2
interleukin 2
chr6_-_25982418 0.702 NM_001098486
NM_006632
SLC17A3

solute carrier family 17 (sodium phosphate), member 3

chr3_+_99350859 0.697 NM_001005514
OR5H14
olfactory receptor, family 5, subfamily H, member 14
chr14_-_106352471 0.695


chrX_+_92815667 0.691 NM_001171109
NM_001171110
NM_001171111
NM_173698
FAM133A



family with sequence similarity 133, member A



chr3_-_71860958 0.687 NM_001134650
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr6_+_144227265 0.678 NM_001013623
C6orf94
chromosome 6 open reading frame 94
chr5_-_37220702 0.677 C5orf42
chromosome 5 open reading frame 42
chr9_+_124477135 0.676 NM_001005234
OR1L3
olfactory receptor, family 1, subfamily L, member 3
chr20_+_29420081 0.672 NM_054112
DEFB118
defensin, beta 118
chr15_+_46285789 0.666 NM_000338
NM_001184832
SLC12A1

solute carrier family 12 (sodium/potassium/chloride transporters), member 1

chr1_+_205694237 0.663 NM_001006658
NM_001877
CR2

complement component (3d/Epstein Barr virus) receptor 2

chr10_+_51246290 0.654 NM_001145262
NCOA4
nuclear receptor coactivator 4
chrX_+_8392870 0.637 NM_001001888
VCX3B
VCX3A
variable charge, X-linked 3B
variable charge, X-linked 3A
chr2_-_158008763 0.636 NM_004288
CYTIP
cytohesin 1 interacting protein
chr3_+_125586241 0.629 KALRN
kalirin, RhoGEF kinase
chr11_-_121492010 0.626 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr6_-_109795925 0.624 CD164
CD164 molecule, sialomucin
chr20_+_15125503 0.623 NM_001033087
MACROD2
MACRO domain containing 2
chr4_+_71261066 0.618 NM_012390
SMR3B
SMR3A
submaxillary gland androgen regulated protein 3B
submaxillary gland androgen regulated protein 3A
chr9_-_70780574 0.616


chr1_-_148936123 0.611 NM_018178
GOLPH3L
golgi phosphoprotein 3-like
chr12_-_3852655 0.609 NM_020367
PARP11
poly (ADP-ribose) polymerase family, member 11
chr18_+_30427279 0.602 NM_001128175
NM_001198938
NM_001198939
NM_001198940
DTNA



dystrobrevin, alpha



chr11_-_55128424 0.600 NM_001004700
OR4C11
olfactory receptor, family 4, subfamily C, member 11
chr11_+_124329286 0.594 CCDC15
coiled-coil domain containing 15
chr12_-_10498481 0.588 NM_213657
NM_213658
KLRC1

killer cell lectin-like receptor subfamily C, member 1

chr9_-_21132143 0.570 NM_002177
IFNW1
interferon, omega 1
chr17_-_3283884 0.555 NM_003554
OR1E2
olfactory receptor, family 1, subfamily E, member 2
chr10_-_98280299 0.551 TM9SF3
transmembrane 9 superfamily member 3
chrX_-_84250629 0.551 NM_001012980
SATL1
spermidine/spermine N1-acetyl transferase-like 1
chr5_-_160044844 0.544 ATP10B
ATPase, class V, type 10B
chr17_+_36636404 0.542 NM_031961
KRTAP9-2
keratin associated protein 9-2
chrX_-_83644054 0.534 NM_001177478
NM_001177479
NM_144657
HDX


highly divergent homeobox


chr17_+_6288457 0.513 NM_001195228
NM_019013
FAM64A

family with sequence similarity 64, member A

chr11_+_124329222 0.511 NM_025004
CCDC15
coiled-coil domain containing 15
chr11_+_58668827 0.508 NM_022074
NM_198847
FAM111A

family with sequence similarity 111, member A

chr6_+_88111289 0.506 NM_001010868
C6orf163
chromosome 6 open reading frame 163
chr4_+_95595419 0.494 PDLIM5
PDZ and LIM domain 5
chr9_-_138762725 0.488 NM_198946
LCN6
lipocalin 6
chr11_-_49960646 0.485 NM_001005270
OR4C12
olfactory receptor, family 4, subfamily C, member 12
chr21_-_30893063 0.484 NM_181604
KRTAP6-2
keratin associated protein 6-2
chr10_+_24538094 0.484 KIAA1217
KIAA1217
chr21_-_30774502 0.479 NM_181607
KRTAP19-1
keratin associated protein 19-1
chr8_+_54926920 0.475 NM_170587
RGS20
regulator of G-protein signaling 20
chr6_+_54819527 0.474 NM_001010872
FAM83B
family with sequence similarity 83, member B
chr11_-_56166490 0.473 NM_001002925
OR5AP2
olfactory receptor, family 5, subfamily AP, member 2
chr11_-_30910074 0.468 NM_020869
DCDC5
doublecortin domain containing 5
chr8_-_25338472 0.467 NM_000825
NM_001083111
GNRH1

gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)

chr14_+_20568184 0.466 NM_173846
TPPP2
tubulin polymerization-promoting protein family member 2
chr8_+_9990471 0.464 NM_001135671
MSRA
methionine sulfoxide reductase A
chr11_+_55078358 0.463 NM_001001920
OR4C15
olfactory receptor, family 4, subfamily C, member 15
chr9_+_106306275 0.460 NM_001004485
OR13F1
olfactory receptor, family 13, subfamily F, member 1
chr5_-_138822475 0.456 NM_001077693
ECSCR
endothelial cell-specific chemotaxis regulator
chr13_+_94883853 0.447 NM_001160100
NM_182848
CLDN10

claudin 10

chr6_-_6632197 0.446


chr5_+_140723939 0.439 NM_018918
NM_032054
PCDHGA5

protocadherin gamma subfamily A, 5

chr5_+_34723420 0.437 NM_001145523
RAI14
retinoic acid induced 14
chr2_+_183316574 0.434 DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr11_-_48330574 0.432 NM_001005513
OR4C45
olfactory receptor, family 4, subfamily C, member 45
chr11_+_123945102 0.429 NM_001005194
OR8A1
olfactory receptor, family 8, subfamily A, member 1
chr9_-_103237851 0.426 NM_000035
ALDOB
aldolase B, fructose-bisphosphate
chr15_+_42808611 0.424 TRIM69
tripartite motif containing 69
chr1_-_151614681 0.423 NM_005621
S100A12
S100 calcium binding protein A12
chr2_+_165860528 0.418 NM_001040143
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr12_+_99391870 0.404 NR1H4
nuclear receptor subfamily 1, group H, member 4
chr16_-_3783475 0.403 CREBBP
CREB binding protein
chr13_+_107753764 0.401


chr16_+_70654625 0.397 NM_020995
HPR
haptoglobin-related protein
chr1_+_66570683 0.397 PDE4B
phosphodiesterase 4B, cAMP-specific
chr3_-_166278969 0.393 NM_001041
SI
sucrase-isomaltase (alpha-glucosidase)
chr8_+_107807415 0.391 NM_001198534
NM_001198535
OXR1

oxidation resistance 1

chr17_+_72692889 0.389 NM_001144001
SEC14L1
SEC14-like 1 (S. cerevisiae)
chr2_-_215957927 0.387 FN1
fibronectin 1
chr5_+_140546839 0.381 NM_019119
PCDHB9
protocadherin beta 9
chr4_-_20594645 0.379 KCNIP4
Kv channel interacting protein 4
chr19_-_47623340 0.371 NM_005357
LIPE
lipase, hormone-sensitive
chr12_+_8557402 0.361 NM_080387
CLEC4D
C-type lectin domain family 4, member D
chr13_+_42253685 0.358 NM_182508
C13orf30
chromosome 13 open reading frame 30
chr6_+_64414389 0.357 NM_015153
PHF3
PHD finger protein 3
chr11_+_59001421 0.353 NM_001004705
OR4D10
olfactory receptor, family 4, subfamily D, member 10
chr17_-_10362583 0.349 NM_005963
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr1_-_151310707 0.343 NM_001017418
SPRR2B
small proline-rich protein 2B
chr1_-_202402043 0.341 NM_000537
REN
renin
chr12_+_15366712 0.341 NM_002848
NM_030667
PTPRO

protein tyrosine phosphatase, receptor type, O

chr9_-_36365965 0.340 RNF38
ring finger protein 38
chr10_-_91092410 0.339 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr6_+_132901119 0.332 NM_175057
TAAR9
trace amine associated receptor 9 (gene/pseudogene)
chr8_+_92184022 0.330 NM_001129890
LRRC69
leucine rich repeat containing 69
chr11_+_55189189 0.329 NM_001004704
OR4C6
olfactory receptor, family 4, subfamily C, member 6
chr6_+_88026338 0.327 ZNF292
zinc finger protein 292
chr21_-_30908093 0.325 NM_181602
KRTAP6-1
keratin associated protein 6-1
chr16_+_31446703 0.322 NM_016633
AHSP
alpha hemoglobin stabilizing protein
chr9_+_12683385 0.321 NM_000550
TYRP1
tyrosinase-related protein 1
chr3_+_133518900 0.320 NM_001099
NM_001134194
ACPP

acid phosphatase, prostate

chr11_+_58967192 0.320 NM_001004728
OR5A1
olfactory receptor, family 5, subfamily A, member 1
chr17_+_57811645 0.311 NM_173503
EFCAB3
EF-hand calcium binding domain 3
chr1_+_190811479 0.308 NM_002922
RGS1
regulator of G-protein signaling 1
chr8_+_32698892 0.308 NM_001159996
NRG1
neuregulin 1
chr11_+_55343658 0.305 NM_001001952
OR5D18
olfactory receptor, family 5, subfamily D, member 18
chr2_-_202192097 0.305 ALS2CR11
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11
chr10_+_49563520 0.304 NM_020945
WDFY4
WDFY family member 4
chr4_-_107508040 0.301 NM_001195138
LOC100507096
GTPase IMAP family member-like
chr8_-_82522175 0.300 NM_002677
PMP2
peripheral myelin protein 2
chr3_-_99236520 0.300 NM_001105580
GABRR3
gamma-aminobutyric acid (GABA) receptor, rho 3
chr5_+_180348450 0.296 NM_197975
BTNL3
butyrophilin-like 3
chr14_+_23527866 0.296 NM_198083
DHRS4
DHRS4L2
dehydrogenase/reductase (SDR family) member 4
dehydrogenase/reductase (SDR family) member 4 like 2
chr9_-_99740243 0.294 NM_197978
HEMGN
hemogen
chr2_+_190710730 0.293 NM_001042521
C2orf88
chromosome 2 open reading frame 88
chr3_-_53139457 0.292 NM_052859
RFT1
RFT1 homolog (S. cerevisiae)
chr12_-_10433852 0.283 NM_007360
KLRK1
killer cell lectin-like receptor subfamily K, member 1
chr10_+_96433240 0.283 NM_000772
NM_001128925
CYP2C18

cytochrome P450, family 2, subfamily C, polypeptide 18

chr1_+_67404756 0.280 NM_144701
IL23R
interleukin 23 receptor
chr2_+_102136833 0.280 NM_000877
IL1R1
interleukin 1 receptor, type I
chrX_-_105169370 0.279 NM_000354
SERPINA7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr11_+_123282307 0.278 NM_001005197
OR8D4
olfactory receptor, family 8, subfamily D, member 4
chr8_+_50987149 0.278 NM_018967
SNTG1
syntrophin, gamma 1
chr4_+_71054492 0.276 NM_214711
C4orf40
chromosome 4 open reading frame 40
chrX_-_135691168 0.276 NM_004840
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr10_+_96943946 0.275 NM_207321
C10orf129
chromosome 10 open reading frame 129
chr7_+_94953148 0.274 NM_016116
NM_145872
ASB4

ankyrin repeat and SOCS box containing 4

chr13_+_77213295 0.273 NM_144595
SLAIN1
SLAIN motif family, member 1
chr12_-_10850845 0.272 NM_023918
TAS2R8
taste receptor, type 2, member 8
chr5_+_140742585 0.271 NM_018920
NM_032087
PCDHGA7

protocadherin gamma subfamily A, 7

chr8_-_131483395 0.269 NM_018482
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr17_-_59825221 0.267


chrX_+_135210787 0.265 NM_153834
GPR112
G protein-coupled receptor 112
chr1_+_86942810 0.265 NM_016009
SH3GLB1
SH3-domain GRB2-like endophilin B1
chr11_-_55757236 0.264 NM_001004746
OR5T2
olfactory receptor, family 5, subfamily T, member 2
chr4_-_70115037 0.264 NM_001073
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr17_-_61253122 0.264 NM_001037325
CCDC46
coiled-coil domain containing 46
chr4_-_70396167 0.263 NM_021139
UGT2B4
UDP glucuronosyltransferase 2 family, polypeptide B4
chr15_-_77994652 0.261 NM_001100879
ST20
suppressor of tumorigenicity 20
chr2_-_215998181 0.261 FN1
fibronectin 1
chr3_-_173723754 0.261 NM_001190943
NM_001190942
NM_003810
TNFSF10


tumor necrosis factor (ligand) superfamily, member 10


chr3_+_133518966 0.260 ACPP
acid phosphatase, prostate
chr1_-_150819586 0.258 NM_032563
LCE3D
late cornified envelope 3D
chr11_-_106941633 0.256 NM_138775
ALKBH8
alkB, alkylation repair homolog 8 (E. coli)
chr2_+_108360798 0.256 NM_006588
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr1_+_172683834 0.255 NM_005684
GPR52
G protein-coupled receptor 52
chr12_+_46802695 0.254 NM_001166687
NM_001166688
PFKM

phosphofructokinase, muscle

chr1_-_151333624 0.251 NM_001024209
SPRR2E
small proline-rich protein 2E
chr6_-_30748760 0.249 NM_001164239
NM_003587
DHX16

DEAH (Asp-Glu-Ala-His) box polypeptide 16

chr6_+_132915522 0.249 NM_053278
TAAR8
trace amine associated receptor 8
chr1_+_152229861 0.247 NM_001030
RPS27
ribosomal protein S27
chr6_+_153060722 0.246 NM_025107
MYCT1
myc target 1
chr12_-_10453409 0.246 NM_013431
KLRC4-KLRK1
KLRC4
KLRC4-KLRK1 read-through transcript
killer cell lectin-like receptor subfamily C, member 4
chr1_+_213245507 0.245 NM_001017424
KCNK2
potassium channel, subfamily K, member 2
chr1_-_245988330 0.244 NM_012353
OR1C1
olfactory receptor, family 1, subfamily C, member 1
chr21_+_30734467 0.243 NM_181623
KRTAP15-1
keratin associated protein 15-1
chr22_+_27998367 0.240 EWSR1
Ewing sarcoma breakpoint region 1
chr2_-_225073357 0.239 CUL3
cullin 3
chr6_-_88095714 0.238 NM_198568
GJB7
gap junction protein, beta 7, 25kDa
chrX_+_87888881 0.237 NM_001184771
NM_033048
CPXCR1

CPX chromosome region, candidate 1

chr1_+_173111306 0.235 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr10_-_45350804 0.234 NM_001002266
MARCH8
membrane-associated ring finger (C3HC4) 8
chr9_-_32516164 0.231 NM_014314
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr2_+_114916368 0.231 NM_020868
DPP10
dipeptidyl-peptidase 10 (non-functional)
chr15_-_48198697 0.231 NM_024837
ATP8B4
ATPase, class I, type 8B, member 4
chr5_+_147695314 0.227 NM_001040433
SPINK9
serine peptidase inhibitor, Kazal type 9
chr14_-_19553191 0.226 NM_001004712
OR4K14
olfactory receptor, family 4, subfamily K, member 14
chr11_+_54891935 0.226 NM_001005275
OR4A15
olfactory receptor, family 4, subfamily A, member 15
chr9_-_35804997 0.223 HINT2
histidine triad nucleotide binding protein 2
chr11_+_59580705 0.220 MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr1_+_116727514 0.219 NM_001160234
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr20_-_118263 0.219 NM_001037732
DEFB128
defensin, beta 128
chr9_-_21295311 0.219 NM_002169
IFNA5
interferon, alpha 5
chr10_+_118295417 0.219 NM_000936
PNLIP
pancreatic lipase
chr12_+_99391681 0.218 NM_005123
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr1_+_195179533 0.217 NM_005666
CFHR2
complement factor H-related 2
chr3_-_121065112 0.216


chr6_-_131426080 0.211 NM_001135555
NM_001135554
NM_001431
EPB41L2


erythrocyte membrane protein band 4.1-like 2


chr21_+_30895276 0.207 NM_181620
KRTAP22-1
keratin associated protein 22-1
chr8_+_7332600 0.206 NM_152250
NM_001040703
DEFB105A
DEFB105B
defensin, beta 105A
defensin, beta 105B
chrX_-_106248706 0.205 NM_001171080
NM_018301
RBM41

RNA binding motif protein 41

chr11_-_85115105 0.205 NM_206927
NM_206928
SYTL2

synaptotagmin-like 2

chrX_-_37916138 0.204 SRPX
sushi-repeat containing protein, X-linked
chr7_-_121731721 0.204 NM_001024613
NM_001160264
FEZF1

FEZ family zinc finger 1


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
4.33 5.89e-17 GO:0007606 sensory perception of chemical stimulus
4.57 6.38e-17 GO:0007608 sensory perception of smell
2.82 2.08e-10 GO:0007600 sensory perception
2.13 9.22e-10 GO:0003008 system process
1.44 9.51e-09 GO:0050896 response to stimulus
2.18 5.81e-08 GO:0050877 neurological system process
1.40 4.15e-05 GO:0032501 multicellular organismal process
2.03 1.00e-02 GO:0006952 defense response

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.56 6.41e-09 GO:0071944 cell periphery
1.56 7.11e-09 GO:0005886 plasma membrane
1.32 5.49e-04 GO:0016021 integral to membrane
1.30 1.35e-03 GO:0031224 intrinsic to membrane
1.58 1.44e-03 GO:0005576 extracellular region
1.24 6.61e-03 GO:0044425 membrane part
1.18 4.73e-02 GO:0016020 membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
4.79 1.82e-18 GO:0004984 olfactory receptor activity
3.07 1.16e-14 GO:0004930 G-protein coupled receptor activity
2.47 1.42e-12 GO:0004888 transmembrane receptor activity
2.01 1.26e-08 GO:0004872 receptor activity
1.75 4.05e-06 GO:0004871 signal transducer activity
1.75 4.05e-06 GO:0060089 molecular transducer activity