Motif ID: GATA1..3.p2

Z-value: 2.039


Transcription factors associated with GATA1..3.p2:

Gene SymbolEntrez IDGene Name
GATA1 2623 GATA binding protein 1 (globin transcription factor 1)
GATA2 2624 GATA binding protein 2
GATA3 2625 GATA binding protein 3



Activity profile for motif GATA1..3.p2.

activity profile for motif GATA1..3.p2


Sorted Z-values histogram for motif GATA1..3.p2

Sorted Z-values for motif GATA1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_170864111 2.635 NM_004991
MECOM
MDS1 and EVI1 complex locus
chr12_+_1608672 2.184 NM_032642
WNT5B
wingless-type MMTV integration site family, member 5B
chrX_-_57953578 2.108 NM_007156
ZXDA
zinc finger, X-linked, duplicated A
chr17_-_7036490 2.016


chrX_+_53095230 1.980 NM_018969
GPR173
G protein-coupled receptor 173
chrX_-_50403412 1.972 SHROOM4
shroom family member 4
chr18_+_19706979 1.827 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chrX_-_63362227 1.822 NM_130388
ASB12
ankyrin repeat and SOCS box containing 12
chrX_+_41191630 1.772 NM_022567
NYX
nyctalopin
chr5_-_160044844 1.687 ATP10B
ATPase, class V, type 10B
chrX_-_152889815 1.649 NM_005334
HCFC1
host cell factor C1 (VP16-accessory protein)
chr15_+_100175888 1.581 NM_001001674
OR4F15
olfactory receptor, family 4, subfamily F, member 15
chrX_-_55037235 1.555 NM_002625
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr21_-_35153664 1.535 RUNX1
runt-related transcription factor 1
chrX_+_110252960 1.532 NM_001128168
NM_001128172
NM_001128173
PAK3


p21 protein (Cdc42/Rac)-activated kinase 3


chr12_+_93066370 1.531 NM_005761
PLXNC1
plexin C1
chr5_+_180514548 1.522 NM_206880
OR2V2
olfactory receptor, family 2, subfamily V, member 2
chrX_-_110541029 1.450 NM_000555
DCX
doublecortin
chr9_-_34387786 1.438 NM_032596
C9orf24
chromosome 9 open reading frame 24
chr11_-_16380967 1.427 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr1_-_226679648 1.359 NM_003493
HIST3H3
histone cluster 3, H3
chr5_+_170668892 1.352 NM_021025
TLX3
T-cell leukemia homeobox 3
chr17_+_39990124 1.316 NM_001466
FZD2
frizzled homolog 2 (Drosophila)
chr10_-_54201400 1.311 NM_000242
MBL2
mannose-binding lectin (protein C) 2, soluble
chr11_+_59001421 1.253 NM_001004705
OR4D10
olfactory receptor, family 4, subfamily D, member 10
chr7_+_38984133 1.227 NM_001166018
NM_007252
POU6F2

POU class 6 homeobox 2

chrX_-_44945025 1.205 NM_024689
NM_176819
CXorf36

chromosome X open reading frame 36

chrX_+_110074124 1.186 NM_001128166
NM_001128167
PAK3

p21 protein (Cdc42/Rac)-activated kinase 3

chr9_+_21399132 1.177 NM_002170
IFNA8
interferon, alpha 8
chrX_-_39532391 1.166


chrX_+_106057984 1.148 CLDN2
claudin 2
chr9_-_16717887 1.098 BNC2
basonuclin 2
chr5_-_145232723 1.097 NM_001080516
GRXCR2
glutaredoxin, cysteine rich 2
chr11_+_110631916 1.095 NM_198498
C11orf53
chromosome 11 open reading frame 53
chr9_-_35948150 1.095 NM_019897
OR2S2
olfactory receptor, family 2, subfamily S, member 2
chr22_-_37211467 1.085 DDX17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chrX_-_24600661 1.082 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr16_-_28425632 1.070 NM_145659
IL27
interleukin 27
chrX_-_70243362 1.061 NM_001025265
CXorf65
chromosome X open reading frame 65
chr6_-_132952517 1.049 NM_003967
TAAR5
trace amine associated receptor 5
chr4_+_42590038 1.049 NM_001080476
GRXCR1
glutaredoxin, cysteine rich 1
chrX_-_53646332 1.046 HUWE1
HECT, UBA and WWE domain containing 1
chr9_-_94566823 1.044 NM_001003800
NM_015250
BICD2

bicaudal D homolog 2 (Drosophila)

chr7_-_31347032 1.037 NM_022728
NEUROD6
neurogenic differentiation 6
chr7_+_143263191 1.017 NM_001004685
OR2F2
olfactory receptor, family 2, subfamily F, member 2
chr10_+_104995633 1.010 NM_001143909
LOC729020
rcRPE
chrX_+_35974973 1.005 NM_173695
CXorf59
chromosome X open reading frame 59
chr11_-_95715976 0.997 NM_032427
MAML2
mastermind-like 2 (Drosophila)
chrX_-_33267646 0.996 NM_000109
DMD
dystrophin
chr7_-_19778928 0.992 NM_152774
TMEM196
transmembrane protein 196
chr12_-_51457371 0.981 NM_015848
KRT76
keratin 76
chr14_-_100420936 0.974 NM_001134888
RTL1
retrotransposon-like 1
chr8_+_65655367 0.969 NM_152414
BHLHE22
basic helix-loop-helix family, member e22
chr9_-_21177529 0.968 NM_021068
IFNA4
interferon, alpha 4
chrX_-_49008115 0.957 NM_001114377
NM_014009
FOXP3

forkhead box P3

chrX_-_111970662 0.953 NM_133265
AMOT
angiomotin
chr6_-_101018271 0.936 NM_005068
SIM1
single-minded homolog 1 (Drosophila)
chrX_-_10605726 0.933 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr5_-_146415782 0.931 NM_181674
NM_181676
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chrX_+_78087484 0.910 NM_014499
NM_198333
P2RY10

purinergic receptor P2Y, G-protein coupled, 10

chr6_+_50894397 0.910 NM_003221
TFAP2B
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr10_+_99339344 0.909 NM_001009997
C10orf62
chromosome 10 open reading frame 62
chr7_-_99312591 0.902 NM_001005276
OR2AE1
olfactory receptor, family 2, subfamily AE, member 1
chr13_+_24568275 0.887 NM_030979
PABPC3
poly(A) binding protein, cytoplasmic 3
chr1_-_146569159 0.883 NM_001164261
NM_001164262
NM_001144032
PPIAL4D
PPIAL4F
PPIAL4E
peptidylprolyl isomerase A (cyclophilin A)-like 4D
peptidylprolyl isomerase A (cyclophilin A)-like 4F
peptidylprolyl isomerase A (cyclophilin A)-like 4E
chr8_-_144583718 0.883 NM_201589
MAFA
v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
chrX_-_111953009 0.877 NM_001113490
AMOT
angiomotin
chrX_-_135941498 0.871 NM_054021
GPR101
G protein-coupled receptor 101
chr1_+_109450116 0.858


chrX_-_62487693 0.846 NM_001012968
SPIN4
spindlin family, member 4
chr15_+_89570333 0.842 SV2B
synaptic vesicle glycoprotein 2B
chr11_-_123772456 0.839 NM_001005467
OR8B3
olfactory receptor, family 8, subfamily B, member 3
chr10_+_25504295 0.837 NM_020752
GPR158
G protein-coupled receptor 158
chr15_+_41597097 0.836 NM_002373
MAP1A
microtubule-associated protein 1A
chrX_-_10495476 0.834 NM_001193278
NM_001193279
NM_001193280
NM_001193281
MID1



midline 1 (Opitz/BBB syndrome)



chr3_+_51964369 0.832 NM_080865
GPR62
G protein-coupled receptor 62
chrX_-_154216929 0.830 NM_001289
CLIC2
chloride intracellular channel 2
chr4_-_164754106 0.828 NM_017923
MARCH1
membrane-associated ring finger (C3HC4) 1
chr11_+_91724909 0.824 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr22_+_36549334 0.819 NM_003614
GALR3
galanin receptor 3
chr17_+_7416780 0.817 NM_001416
EIF4A1
eukaryotic translation initiation factor 4A1
chrX_-_50573759 0.808 NM_020717
SHROOM4
shroom family member 4
chrX_-_77469635 0.805 NM_006639
CYSLTR1
cysteinyl leukotriene receptor 1
chr11_-_55460451 0.803 NM_006637
OR5I1
olfactory receptor, family 5, subfamily I, member 1
chr14_+_59934178 0.802


chr11_+_55776251 0.800 NM_001004747
OR5T3
olfactory receptor, family 5, subfamily T, member 3
chr17_-_3248453 0.797 NM_003553
OR1E1
olfactory receptor, family 1, subfamily E, member 1
chrX_+_102498035 0.797 NM_001006612
NM_001006613
NM_001006614
NM_016303
WBP5



WW domain binding protein 5



chr11_-_19038803 0.792 NM_054030
MRGPRX2
MAS-related GPR, member X2
chr4_-_41445479 0.791 PHOX2B
paired-like homeobox 2b
chr11_-_57643491 0.784 NM_001005211
OR9I1
olfactory receptor, family 9, subfamily I, member 1
chr14_-_60260211 0.782 NM_017420
SIX4
SIX homeobox 4
chrX_-_71850434 0.776 NM_001122670
NM_001172436
NM_002637
PHKA1


phosphorylase kinase, alpha 1 (muscle)


chr9_-_21207303 0.775 NM_002173
IFNA16
interferon, alpha 16
chr15_+_87540238 0.771 ABHD2
abhydrolase domain containing 2
chr13_-_45640679 0.769 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr12_+_79634820 0.769 NM_005593
MYF5
myogenic factor 5
chr15_+_100163424 0.765 NM_001005326
OR4F6
olfactory receptor, family 4, subfamily F, member 6
chrX_+_135397790 0.758 NM_001727
BRS3
bombesin-like receptor 3
chr10_-_21847126 0.754


chrX_+_129133234 0.754 NM_004794
RAB33A
RAB33A, member RAS oncogene family
chrX_-_138552517 0.750 NM_001171877
NM_001171878
NM_001171879
NM_005369
MCF2



MCF.2 cell line derived transforming sequence



chrX_-_21686079 0.744 NM_014332
SMPX
small muscle protein, X-linked
chr11_-_6148131 0.740 NM_001004052
OR52B2
olfactory receptor, family 52, subfamily B, member 2
chr12_-_98072602 0.739 NM_020140
NM_181670
ANKS1B

ankyrin repeat and sterile alpha motif domain containing 1B

chr17_-_9635325 0.738 NM_001105571
DHRS7C
dehydrogenase/reductase (SDR family) member 7C
chrX_+_49013424 0.738 PPP1R3F
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chrX_+_48253007 0.734 NM_203474
NM_203475
PORCN

porcupine homolog (Drosophila)

chrX_+_105823723 0.724 NM_024539
RNF128
ring finger protein 128
chrX_+_57634993 0.722 NM_007157
ZXDB
zinc finger, X-linked, duplicated B
chr2_-_39040981 0.721 LOC375196
hypothetical LOC375196
chr10_-_119124727 0.718 NM_173791
PDZD8
PDZ domain containing 8
chr6_+_108593907 0.707 NM_003269
NR2E1
nuclear receptor subfamily 2, group E, member 1
chr8_+_62363078 0.705 NM_173519
CLVS1
clavesin 1
chr11_-_10546654 0.702 NM_006691
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr6_-_46933901 0.701 GPR116
G protein-coupled receptor 116
chr14_-_57133361 0.699 NM_001080455
SLC35F4
solute carrier family 35, member F4
chr8_+_22266256 0.699 PIWIL2
piwi-like 2 (Drosophila)
chr11_-_8241875 0.692 NM_002315
LMO1
LIM domain only 1 (rhombotin 1)
chr19_+_54299686 0.690 SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)
chr6_-_80713589 0.687 NM_022726
ELOVL4
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
chr11_+_59979857 0.683 NM_021950
NM_152866
MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chr7_+_23496661 0.683 RPS2P32
ribosomal protein S2 pseudogene 32
chr1_+_146910634 0.682 NM_001144032
PPIAL4E
peptidylprolyl isomerase A (cyclophilin A)-like 4E
chr12_-_6995988 0.675 NM_005768
LPCAT3
lysophosphatidylcholine acyltransferase 3
chr11_+_123945102 0.673 NM_001005194
OR8A1
olfactory receptor, family 8, subfamily A, member 1
chr1_-_157003095 0.668 NM_001005185
OR6N1
olfactory receptor, family 6, subfamily N, member 1
chr12_+_48630790 0.667 NM_000486
AQP2
aquaporin 2 (collecting duct)
chrX_+_38305634 0.667 NM_004615
TSPAN7
tetraspanin 7
chrX_-_54226364 0.667 NM_017848
NM_198456
FAM120C

family with sequence similarity 120C

chr11_-_64133908 0.666


chr1_-_143075560 0.665 NM_178230
NM_001143883
NM_001135789
PPIAL4A
PPIAL4G
PPIAL4B
PPIAL4C
peptidylprolyl isomerase A (cyclophilin A)-like 4A
peptidylprolyl isomerase A (cyclophilin A)-like 4G
peptidylprolyl isomerase A (cyclophilin A)-like 4B
peptidylprolyl isomerase A (cyclophilin A)-like 4C
chr17_-_31104009 0.665 NM_139285
GAS2L2
growth arrest-specific 2 like 2
chr17_+_1120607 0.660 NM_001164405
BHLHA9
basic helix-loop-helix family, member a9
chr15_+_52092392 0.659 NM_001080534
UNC13C
unc-13 homolog C (C. elegans)
chr7_-_36992221 0.658 NM_130442
ELMO1
engulfment and cell motility 1
chr3_-_57288019 0.655 NM_130387
ASB14
ankyrin repeat and SOCS box containing 14
chr9_-_34371497 0.652 NM_147168
NM_147169
C9orf24

chromosome 9 open reading frame 24

chr11_+_58967192 0.651 NM_001004728
OR5A1
olfactory receptor, family 5, subfamily A, member 1
chrX_+_66683075 0.651 AR
androgen receptor
chrX_+_69559605 0.649 NM_001171191
NM_001171192
NM_001171193
NM_017711
GDPD2



glycerophosphodiester phosphodiesterase domain containing 2



chr1_-_157551072 0.645 NM_001004467
OR10J3
olfactory receptor, family 10, subfamily J, member 3
chr18_-_55136673 0.644 NM_181654
CPLX4
complexin 4
chr11_+_55869996 0.643 NM_001002907
OR8K1
olfactory receptor, family 8, subfamily K, member 1
chr2_+_218929822 0.641 NM_198559
C2orf62
chromosome 2 open reading frame 62
chrX_+_113724806 0.638 NM_000868
HTR2C
5-hydroxytryptamine (serotonin) receptor 2C
chr11_-_57728228 0.638 NM_001004459
OR1S2
olfactory receptor, family 1, subfamily S, member 2
chrX_-_127014020 0.636 NM_138289
ACTRT1
actin-related protein T1
chr11_+_59038961 0.635 NM_001004711
OR4D9
olfactory receptor, family 4, subfamily D, member 9
chrX_+_82649924 0.633 NM_000307
POU3F4
POU class 3 homeobox 4
chr14_-_59264044 0.631 NM_206857
RTN1
reticulon 1
chrX_+_70360184 0.630 GJB1
gap junction protein, beta 1, 32kDa
chr14_-_47213906 0.629 NM_001113498
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr16_+_3345889 0.628 NM_012368
OR2C1
olfactory receptor, family 2, subfamily C, member 1
chr1_-_157014048 0.627 NM_001005278
OR6N2
olfactory receptor, family 6, subfamily N, member 2
chrX_+_150653873 0.627 NM_005140
CNGA2
cyclic nucleotide gated channel alpha 2
chr9_-_21067804 0.625 NM_002176
IFNB1
interferon, beta 1, fibroblast
chr11_+_5862076 0.625 NM_001005165
OR52E4
olfactory receptor, family 52, subfamily E, member 4
chr4_-_70539922 0.625 NM_001105677
UGT2A2
UDP glucuronosyltransferase 2 family, polypeptide A2
chr1_+_234372454 0.624 NM_003272
GPR137B
G protein-coupled receptor 137B
chr15_+_38923914 0.622 NM_001032367
SPINT1
serine peptidase inhibitor, Kunitz type 1
chrX_+_111005934 0.621 NM_001195576
NM_001195578
LOC100329135

hypothetical LOC100329135

chr10_+_115302767 0.621 NM_004132
HABP2
hyaluronan binding protein 2
chr2_+_204440753 0.615 NM_001037631
NM_005214
CTLA4

cytotoxic T-lymphocyte-associated protein 4

chr18_-_65766068 0.615 CD226
CD226 molecule
chr1_-_26553168 0.612 NM_001039775
AIM1L
absent in melanoma 1-like
chr13_+_27264779 0.611 NM_145657
GSX1
GS homeobox 1
chr19_-_43926953 0.609 NM_144691
CAPN12
calpain 12
chrX_+_57635165 0.608 ZXDB
zinc finger, X-linked, duplicated B
chr1_+_158426908 0.604 NM_001231
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr8_-_42817604 0.603 NM_018105
NM_199003
THAP1

THAP domain containing, apoptosis associated protein 1

chr17_-_75427644 0.601 NM_003655
CBX4
chromobox homolog 4
chrX_+_70232362 0.597 NM_001170931
NM_005938
FOXO4

forkhead box O4

chr14_+_54291255 0.594 NM_001161577
SAMD4A
sterile alpha motif domain containing 4A
chr5_-_151764857 0.592 NM_020167
NMUR2
neuromedin U receptor 2
chrX_-_100527799 0.591 NM_000061
BTK
Bruton agammaglobulinemia tyrosine kinase
chr17_-_77824849 0.590 NM_001893
NM_139062
CSNK1D

casein kinase 1, delta

chrX_+_122145776 0.590 NM_000828
NM_007325
GRIA3

glutamate receptor, ionotrophic, AMPA 3

chr5_-_149649380 0.590 CAMK2A
calcium/calmodulin-dependent protein kinase II alpha
chrX_+_70438352 0.587 NM_012278
ITGB1BP2
integrin beta 1 binding protein (melusin) 2
chrX_+_51503219 0.584 NM_018094
GSPT2
G1 to S phase transition 2
chr1_-_156816312 0.583 NM_001004477
OR10X1
olfactory receptor, family 10, subfamily X, member 1
chr9_+_27099138 0.581 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr3_-_49868889 0.578 NM_005879
TRAIP
TRAF interacting protein
chr11_-_46364681 0.576 NM_000741
CHRM4
cholinergic receptor, muscarinic 4
chr1_+_158317967 0.573 NM_004983
KCNJ9
potassium inwardly-rectifying channel, subfamily J, member 9
chr9_-_21340885 0.572 NM_021002
IFNA6
interferon, alpha 6
chr9_+_36159384 0.571 NM_005893
CCIN
calicin
chr7_-_81237162 0.571 NM_000601
NM_001010931
NM_001010932
NM_001010933
NM_001010934
HGF




hepatocyte growth factor (hepapoietin A; scatter factor)




chr3_-_52065130 0.571 NM_001947
DUSP7
dual specificity phosphatase 7
chrX_-_131401319 0.570 NM_018388
NM_133486
MBNL3

muscleblind-like 3 (Drosophila)

chr12_-_85756766 0.570 NM_013244
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr5_-_146441184 0.568 NM_181677
NM_181678
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr12_+_5473558 0.568 NM_002527
NTF3
neurotrophin 3
chr11_+_130745580 0.566 NM_001048209
NTM
neurotrimin
chr4_-_123761615 0.565 NM_021803
IL21
interleukin 21
chr12_-_46883341 0.560 NM_001004134
OR10AD1
olfactory receptor, family 10, subfamily AD, member 1
chrX_+_49013270 0.558 PPP1R3F
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chrX_+_123307812 0.556 NM_001114937
NM_002351
SH2D1A

SH2 domain containing 1A

chr4_+_76700281 0.554 NM_178497
C4orf26
chromosome 4 open reading frame 26

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.25 1.43e-38 GO:0007608 sensory perception of smell
1.62 4.58e-34 GO:0050877 neurological system process
2.09 3.61e-33 GO:0007606 sensory perception of chemical stimulus
1.54 6.27e-33 GO:0003008 system process
1.27 5.37e-32 GO:0032501 multicellular organismal process
1.76 3.01e-29 GO:0007600 sensory perception
1.15 3.07e-12 GO:0050896 response to stimulus
1.34 4.82e-10 GO:0007399 nervous system development
1.44 1.17e-07 GO:0007267 cell-cell signaling
1.20 3.77e-07 GO:0048731 system development
1.24 1.51e-06 GO:0030154 cell differentiation
1.23 2.76e-06 GO:0048869 cellular developmental process
1.17 6.07e-06 GO:0007275 multicellular organismal development
1.18 9.63e-06 GO:0048856 anatomical structure development
1.33 2.00e-05 GO:0007154 cell communication
1.15 4.78e-05 GO:0032502 developmental process
1.46 5.59e-05 GO:0019226 transmission of nerve impulse
1.46 5.59e-05 GO:0035637 multicellular organismal signaling
1.49 7.69e-05 GO:0007268 synaptic transmission
1.15 1.28e-04 GO:0023052 signaling
1.34 1.36e-04 GO:0048699 generation of neurons
1.32 2.08e-04 GO:0022008 neurogenesis
1.37 2.34e-04 GO:0030182 neuron differentiation
1.42 7.59e-04 GO:0007417 central nervous system development
1.44 1.70e-03 GO:0032583 regulation of gene-specific transcription
1.45 7.63e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.66 2.99e-02 GO:0045165 cell fate commitment
1.45 3.26e-02 GO:0060284 regulation of cell development
1.33 4.09e-02 GO:0048666 neuron development
1.41 4.12e-02 GO:0007420 brain development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.23 4.28e-18 GO:0005886 plasma membrane
1.22 3.48e-17 GO:0071944 cell periphery
1.12 5.44e-06 GO:0031224 intrinsic to membrane
1.09 7.60e-06 GO:0016020 membrane
1.12 8.18e-06 GO:0016021 integral to membrane
1.10 5.45e-05 GO:0044425 membrane part
1.45 1.66e-04 GO:0045202 synapse
1.03 3.28e-04 GO:0005623 cell
1.03 4.01e-04 GO:0044464 cell part
1.42 9.08e-04 GO:0043005 neuron projection
1.47 2.40e-03 GO:0044456 synapse part
1.57 4.21e-02 GO:0045211 postsynaptic membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.31 1.15e-40 GO:0004984 olfactory receptor activity
1.82 3.85e-36 GO:0004930 G-protein coupled receptor activity
1.61 8.22e-32 GO:0004888 transmembrane receptor activity
1.49 1.94e-28 GO:0004872 receptor activity
1.41 1.27e-24 GO:0004871 signal transducer activity
1.41 1.27e-24 GO:0060089 molecular transducer activity
1.39 5.44e-06 GO:0043565 sequence-specific DNA binding
1.29 1.17e-04 GO:0030528 transcription regulator activity
1.63 4.02e-04 GO:0000975 regulatory region DNA binding
1.63 4.02e-04 GO:0001067 regulatory region nucleic acid binding
1.63 4.02e-04 GO:0044212 transcription regulatory region DNA binding
1.51 4.90e-04 GO:0022836 gated channel activity
1.62 1.10e-03 GO:0010843 promoter binding
1.94 2.10e-03 GO:0003705 sequence-specific enhancer binding RNA polymerase II transcription factor activity
1.87 2.89e-03 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
1.94 1.13e-02 GO:0005230 extracellular ligand-gated ion channel activity
1.37 1.69e-02 GO:0015267 channel activity
1.37 1.95e-02 GO:0022803 passive transmembrane transporter activity
1.23 3.10e-02 GO:0001071 nucleic acid binding transcription factor activity
1.23 3.10e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
2.58 3.74e-02 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
1.64 4.78e-02 GO:0015276 ligand-gated ion channel activity
1.64 4.78e-02 GO:0022834 ligand-gated channel activity