Motif ID: GFI1.p2

Z-value: 1.323


Transcription factors associated with GFI1.p2:

Gene SymbolEntrez IDGene Name
GFI1 2672 growth factor independent 1 transcription repressor



Activity profile for motif GFI1.p2.

activity profile for motif GFI1.p2


Sorted Z-values histogram for motif GFI1.p2

Sorted Z-values for motif GFI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_42129620 3.453 NM_001134296
NM_006803
AP3M2

adaptor-related protein complex 3, mu 2 subunit

chr17_+_59053518 2.162 NM_002401
NM_203351
MAP3K3

mitogen-activated protein kinase kinase kinase 3

chr17_+_59053515 2.033 MAP3K3
mitogen-activated protein kinase kinase kinase 3
chr17_+_59053447 2.033 MAP3K3
mitogen-activated protein kinase kinase kinase 3
chr3_+_173951163 1.556 ECT2
epithelial cell transforming sequence 2 oncogene
chr4_+_183302105 1.541 ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr3_+_153499883 1.534 NM_207293
NM_207294
NM_207295
NM_207296
NM_207297
MBNL1




muscleblind-like (Drosophila)




chr17_-_71287417 1.477 NM_005324
H3F3B
H3 histone, family 3B (H3.3B)
chr5_+_162797149 1.251 NM_004060
NM_199246
CCNG1

cyclin G1

chr10_+_5444516 1.247 NM_001047160
NET1
neuroepithelial cell transforming 1
chr17_+_43082273 1.242 NM_002265
KPNB1
karyopherin (importin) beta 1
chr3_-_116348780 1.203 NM_015642
ZBTB20
zinc finger and BTB domain containing 20
chr14_+_57835028 1.180 ARID4A
AT rich interactive domain 4A (RBP1-like)
chr8_+_74083615 1.170 NM_003218
NM_017489
TERF1

telomeric repeat binding factor (NIMA-interacting) 1

chr14_+_57834962 1.139 NM_002892
NM_023000
NM_023001
ARID4A


AT rich interactive domain 4A (RBP1-like)


chr17_+_43082302 1.138 KPNB1
karyopherin (importin) beta 1
chr1_-_205272619 1.137 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr14_-_54727958 1.131 NM_001146015
NM_014750
DLGAP5

discs, large (Drosophila) homolog-associated protein 5

chr1_+_112740378 1.117


chr1_+_25629968 1.103 NM_018202
TMEM57
transmembrane protein 57
chr4_+_86968069 1.091 ARHGAP24
Rho GTPase activating protein 24
chr1_+_6767968 1.075 NM_001195563
NM_015215
CAMTA1

calmodulin binding transcription activator 1

chr17_-_8034071 1.034 C17orf59
chromosome 17 open reading frame 59
chr17_-_8034217 1.026 NM_017622
C17orf59
chromosome 17 open reading frame 59
chr17_-_57295451 1.020 NM_032043
BRIP1
BRCA1 interacting protein C-terminal helicase 1
chr1_+_112740322 1.019 NM_018704
CTTNBP2NL
CTTNBP2 N-terminal like
chr16_+_51722285 1.015 CHD9
chromodomain helicase DNA binding protein 9
chr1_+_112740380 1.007 LOC100129406
CTTNBP2NL
hypothetical protein LOC100129406
CTTNBP2 N-terminal like
chr3_+_121296290 1.001


chr5_-_64894687 0.986 NM_022145
CENPK
centromere protein K
chr17_+_65677255 0.986 NM_000891
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr3_+_9414290 0.973 NM_001080517
SETD5
SET domain containing 5
chr18_+_12981329 0.952 NM_032142
CEP192
centrosomal protein 192kDa
chr3_+_56566222 0.937 NM_001012506
NM_001141947
CCDC66

coiled-coil domain containing 66

chr17_+_57909979 0.927 NM_001112707
NM_006852
TLK2

tousled-like kinase 2

chr10_+_76256305 0.884 NM_012330
MYST4
MYST histone acetyltransferase (monocytic leukemia) 4
chr4_+_157044296 0.880 NM_005651
TDO2
tryptophan 2,3-dioxygenase
chr4_+_148758014 0.879 TMEM184C
transmembrane protein 184C
chr2_+_242679507 0.877 LOC728323
hypothetical LOC728323
chr5_+_64894854 0.871 NM_015342
PPWD1
peptidylprolyl isomerase domain and WD repeat containing 1
chr17_+_43081837 0.865 KPNB1
karyopherin (importin) beta 1
chr7_-_148356433 0.865 PDIA4
protein disulfide isomerase family A, member 4
chr5_+_142130475 0.853 NM_001135608
NM_015071
ARHGAP26

Rho GTPase activating protein 26

chr6_-_33028790 0.843 NM_006120
HLA-DMA
major histocompatibility complex, class II, DM alpha
chr11_+_19095215 0.835 NM_001001483
NM_019028
ZDHHC13

zinc finger, DHHC-type containing 13

chr17_+_43082557 0.827 KPNB1
karyopherin (importin) beta 1
chr2_+_62786290 0.812 NM_001142616
NM_015252
EHBP1

EH domain binding protein 1

chr1_-_148936123 0.810 NM_018178
GOLPH3L
golgi phosphoprotein 3-like
chr9_-_34319151 0.808 NM_194313
KIF24
kinesin family member 24
chr20_+_57942213 0.807 NM_001190826
C20orf177
chromosome 20 open reading frame 177
chr1_+_144188375 0.805 NM_153713
LIX1L
Lix1 homolog (mouse)-like
chr20_-_57942063 0.804 SYCP2
synaptonemal complex protein 2
chr4_+_148757958 0.797 NM_018241
TMEM184C
transmembrane protein 184C
chr3_-_168935287 0.788 NM_007217
NM_145860
NM_145859
PDCD10


programmed cell death 10


chr11_+_43658718 0.783 NM_016142
HSD17B12
hydroxysteroid (17-beta) dehydrogenase 12
chr17_+_20712337 0.776


chr21_-_30577120 0.774 NM_001085455
KRTAP24-1
keratin associated protein 24-1
chr2_+_105834635 0.770 NM_001004720
NCK2
NCK adaptor protein 2
chr3_-_9414122 0.768 LOC440944
hypothetical LOC440944
chr15_+_98960277 0.767 NM_024708
NM_198243
ASB7

ankyrin repeat and SOCS box containing 7

chr7_-_148356697 0.763 NM_004911
PDIA4
protein disulfide isomerase family A, member 4
chr5_+_31568129 0.762 NM_018356
C5orf22
chromosome 5 open reading frame 22
chr12_+_27066768 0.758 MED21
mediator complex subunit 21
chr9_+_91115924 0.748 NM_001827
CKS2
CDC28 protein kinase regulatory subunit 2
chr12_+_63090008 0.747 XPOT
exportin, tRNA (nuclear export receptor for tRNAs)
chr6_-_109795925 0.744 CD164
CD164 molecule, sialomucin
chr12_+_102848344 0.743 HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr11_+_82545784 0.733 NM_015885
PCF11
PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae)
chr4_-_113656762 0.723 NM_024019
NEUROG2
neurogenin 2
chr12_+_102848316 0.721 NM_003299
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr7_-_148356664 0.719 PDIA4
protein disulfide isomerase family A, member 4
chr12_+_27568311 0.718 NM_001198915
NM_001198916
NM_003622
NM_177444
PPFIBP1



PTPRF interacting protein, binding protein 1 (liprin beta 1)



chr9_+_34319503 0.718 NM_001161
NM_147172
NM_147173
NUDT2


nudix (nucleoside diphosphate linked moiety X)-type motif 2


chr14_+_51526071 0.717 C14orf166
chromosome 14 open reading frame 166
chr4_-_76774594 0.716 NM_003948
CDKL2
cyclin-dependent kinase-like 2 (CDC2-related kinase)
chr5_+_72148173 0.715 NM_002270
TNPO1
transportin 1
chr14_+_54046295 0.714 NM_006568
CGRRF1
cell growth regulator with ring finger domain 1
chr12_+_102848322 0.707 HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chrX_+_154097894 0.707 NM_003372
VBP1
von Hippel-Lindau binding protein 1
chr16_+_55523526 0.707 HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr14_+_51525942 0.707 NM_016039
C14orf166
chromosome 14 open reading frame 166
chr4_-_186537145 0.706 NM_018409
LRP2BP
LRP2 binding protein
chr5_+_142130154 0.696 ARHGAP26
Rho GTPase activating protein 26
chr1_+_170768914 0.694 NM_016227
C1orf9
chromosome 1 open reading frame 9
chr12_-_101037976 0.690 NUP37
nucleoporin 37kDa
chr10_+_103995297 0.687 NM_004193
GBF1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr1_-_27212035 0.687 FAM46B
family with sequence similarity 46, member B
chr7_+_132588359 0.685 NM_001037126
NM_021807
EXOC4

exocyst complex component 4

chr12_+_77782719 0.684 SYT1
synaptotagmin I
chr19_+_2792432 0.671 NM_001172775
NM_152791
ZNF555

zinc finger protein 555

chr1_-_11245130 0.668 MTOR
mechanistic target of rapamycin (serine/threonine kinase)
chr18_-_55177430 0.667 NM_005570
LMAN1
lectin, mannose-binding, 1
chr8_-_124613557 0.666 NM_148177
FBXO32
F-box protein 32
chr5_-_110876186 0.664 STARD4
StAR-related lipid transfer (START) domain containing 4
chr4_+_95592030 0.663 NM_001011513
NM_001011515
NM_001011516
NM_006457
PDLIM5



PDZ and LIM domain 5



chr3_+_52545660 0.662 NM_001124767
C3orf78
chromosome 3 open reading frame 78
chr2_+_9264360 0.660 ASAP2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr15_+_80434362 0.654 UBE2Q2P2
ubiquitin-conjugating enzyme E2Q family member 2 pseudogene 2
chr12_-_51759438 0.653 NM_032840
SPRYD3
SPRY domain containing 3
chr12_-_11075272 0.647 NM_176885
TAS2R31
taste receptor, type 2, member 31
chr1_+_210525490 0.646 NM_006243
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr11_-_22603905 0.643 NM_022725
FANCF
Fanconi anemia, complementation group F
chr9_-_124280025 0.639 NM_001004451
OR1J1
olfactory receptor, family 1, subfamily J, member 1
chr10_+_103995248 0.636 GBF1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr12_+_105873803 0.634 C12orf23
chromosome 12 open reading frame 23
chr12_-_51759434 0.629 SPRYD3
SPRY domain containing 3
chr6_-_136613097 0.629 NM_001099286
NM_138419
FAM54A

family with sequence similarity 54, member A

chr15_+_36331411 0.624 SPRED1
sprouty-related, EVH1 domain containing 1
chr5_-_40791766 0.624 NM_012382
TTC33
tetratricopeptide repeat domain 33
chr12_-_48705427 0.623 NM_001126103
NM_001126104
NM_013277
RACGAP1


Rac GTPase activating protein 1


chr3_+_112876212 0.621 NM_001185106
NM_153268
PLCXD2

phosphatidylinositol-specific phospholipase C, X domain containing 2

chr7_+_65307816 0.620 TPST1
tyrosylprotein sulfotransferase 1
chr17_+_23394062 0.620 NLK
nemo-like kinase
chr3_+_184648089 0.617 LOC100505687
hypothetical LOC100505687
chr7_+_87095640 0.617 NM_001134405
NM_001134406
NM_138290
RUNDC3B


RUN domain containing 3B


chr5_-_157011665 0.615


chr10_-_99436889 0.613 NM_021732
AVPI1
arginine vasopressin-induced 1
chr3_+_170974745 0.611 NM_001185119
MYNN
myoneurin
chr12_+_105873669 0.611 NM_152261
C12orf23
chromosome 12 open reading frame 23
chr19_-_21826609 0.599 ZNF43
zinc finger protein 43
chr7_+_106596641 0.596 NM_012257
HBP1
HMG-box transcription factor 1
chr11_-_5037432 0.593 NM_001005164
OR52E2
olfactory receptor, family 52, subfamily E, member 2
chr12_+_102848287 0.593 HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr11_+_82290384 0.592 NM_145018
C11orf82
chromosome 11 open reading frame 82
chr6_+_99389300 0.587 NM_005604
POU3F2
POU class 3 homeobox 2
chr13_+_99539269 0.586 NM_000282
NM_001127692
NM_001178004
PCCA


propionyl CoA carboxylase, alpha polypeptide


chr17_+_64019693 0.583 NM_212471
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr7_-_86686754 0.582 NM_024315
C7orf23
chromosome 7 open reading frame 23
chr3_+_56566277 0.581 CCDC66
coiled-coil domain containing 66
chr12_+_94776836 0.580 NM_003095
SNRPF
small nuclear ribonucleoprotein polypeptide F
chr7_+_99974781 0.577 AGFG2
ArfGAP with FG repeats 2
chr21_+_43186428 0.576 NM_001001503
NM_021075
NDUFV3

NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa

chr12_+_48303607 0.574 NM_012272
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr11_+_31487872 0.572 NM_019040
ELP4
elongation protein 4 homolog (S. cerevisiae)
chr4_+_95592067 0.571 PDLIM5
PDZ and LIM domain 5
chr17_+_43540124 0.571 SNX11
sorting nexin 11
chr12_-_11106159 0.569 NM_176887
TAS2R46
taste receptor, type 2, member 46
chr1_-_11245172 0.568 MTOR
mechanistic target of rapamycin (serine/threonine kinase)
chr7_+_65307691 0.567 NM_003596
TPST1
tyrosylprotein sulfotransferase 1
chr5_-_39238818 0.563 FYB
FYN binding protein
chr8_+_67849972 0.561 NM_013257
NM_170709
SGK3

serum/glucocorticoid regulated kinase family, member 3

chr5_-_110876055 0.560 NM_139164
STARD4
StAR-related lipid transfer (START) domain containing 4
chr3_-_187771025 0.555 NM_001134415
TBCCD1
TBCC domain containing 1
chr7_-_104440707 0.553 LOC100216545
hypothetical LOC100216545
chr1_-_27211913 0.553 NM_052943
FAM46B
family with sequence similarity 46, member B
chr10_+_120779217 0.552 NM_199461
NANOS1
nanos homolog 1 (Drosophila)
chr1_+_179324458 0.551 IER5
immediate early response 5
chr5_+_60663842 0.550 NM_020928
ZSWIM6
zinc finger, SWIM-type containing 6
chr4_+_177477997 0.550 NM_021928
SPCS3
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chr15_+_39310757 0.549 CHP
calcium binding protein P22
chr17_+_70964258 0.547 NM_014738
KIAA0195
KIAA0195
chr11_+_7463175 0.546 NM_198474
OLFML1
olfactomedin-like 1
chr14_+_101346032 0.546 PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr3_-_27473248 0.545 NM_003615
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr4_+_177478103 0.544 SPCS3
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chr10_+_112669349 0.543 SHOC2
soc-2 suppressor of clear homolog (C. elegans)
chr3_+_142587973 0.543


chr7_+_91996022 0.543 NM_032120
C7orf64
chromosome 7 open reading frame 64
chrX_+_133334965 0.542 NM_001015877
NM_032335
NM_032458
PHF6


PHD finger protein 6


chr9_+_33614214 0.541 ANXA2P2
annexin A2 pseudogene 2
chr7_-_104441285 0.541 LOC100216545
hypothetical LOC100216545
chr1_+_213807321 0.536 NM_016121
KCTD3
potassium channel tetramerisation domain containing 3
chr4_-_457839 0.535 ABCA11P
ATP-binding cassette, sub-family A (ABC1), member 11 (pseudogene)
chr7_-_112366962 0.533 NM_152556
C7orf60
chromosome 7 open reading frame 60
chr1_+_13948518 0.533 PRDM2
PR domain containing 2, with ZNF domain
chr15_+_75010997 0.532 NM_002902
RCN2
reticulocalbin 2, EF-hand calcium binding domain
chr17_-_45196516 0.532 NM_030802
FAM117A
family with sequence similarity 117, member A
chr5_+_133735004 0.530 UBE2B
ubiquitin-conjugating enzyme E2B (RAD6 homolog)
chr1_+_13948448 0.530 NM_001007257
PRDM2
PR domain containing 2, with ZNF domain
chr1_-_11245181 0.528 MTOR
mechanistic target of rapamycin (serine/threonine kinase)
chr20_+_33823318 0.528 NM_016436
PHF20
PHD finger protein 20
chr1_+_42619014 0.527 NM_173642
RIMKLA
ribosomal modification protein rimK-like family member A
chr15_-_98959898 0.524 NM_001040616
LINS
lines homolog (Drosophila)
chr8_-_103737058 0.523 NM_005655
KLF10
Kruppel-like factor 10
chr2_-_179380301 0.523 NM_003319
NM_133378
NM_133379
NM_133432
NM_133437
TTN




titin




chr1_-_7998265 0.520 ERRFI1
ERBB receptor feedback inhibitor 1
chr1_+_170768635 0.520 NM_014283
C1orf9
chromosome 1 open reading frame 9
chr4_+_160408447 0.519 NM_014247
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr10_-_112668679 0.519 NM_001195306
BBIP1
BBSome interacting protein 1
chr11_-_31487685 0.517 NM_144981
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr17_+_43539909 0.517 NM_152244
NM_013323
SNX11

sorting nexin 11

chr1_-_11245193 0.517 NM_004958
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
chr1_-_23543330 0.517 NM_001102397
NM_001102398
NM_001102399
NM_005826
HNRNPR



heterogeneous nuclear ribonucleoprotein R



chr5_-_92982927 0.514


chr10_+_112669353 0.513 SHOC2
soc-2 suppressor of clear homolog (C. elegans)
chr5_-_58331515 0.513 NM_001197223
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_+_143078202 0.512 ATP1B3
ATPase, Na+/K+ transporting, beta 3 polypeptide
chr19_+_2818332 0.511 NM_024967
ZNF556
zinc finger protein 556
chr11_+_107497462 0.510 NM_000019
ACAT1
acetyl-CoA acetyltransferase 1
chr15_-_54544531 0.509 NM_018365
MNS1
meiosis-specific nuclear structural 1
chr11_-_129377929 0.509 NM_020228
NM_199437
PRDM10

PR domain containing 10

chr12_-_11136178 0.509 NM_176884
TAS2R43
taste receptor, type 2, member 43
chr12_+_27066749 0.508 NM_004264
MED21
mediator complex subunit 21
chr1_-_159257486 0.504 F11R
F11 receptor
chr17_-_45196465 0.502 FAM117A
family with sequence similarity 117, member A
chr2_+_61146866 0.502 NM_032506
KIAA1841
KIAA1841
chr5_-_27074407 0.501 NM_016279
CDH9
cadherin 9, type 2 (T1-cadherin)
chr5_-_150118274 0.501 NM_001135644
DCTN4
dynactin 4 (p62)
chr17_-_36181927 0.500 NM_181539
KRT26
keratin 26
chr5_+_179065282 0.499 CANX
calnexin

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.67 7.16e-03 GO:0000279 M phase
1.40 1.42e-02 GO:0007049 cell cycle
2.34 1.54e-02 GO:0065004 protein-DNA complex assembly
1.53 1.74e-02 GO:0051276 chromosome organization
2.29 1.77e-02 GO:0071824 protein-DNA complex subunit organization
1.45 1.81e-02 GO:0022402 cell cycle process
1.46 3.26e-02 GO:0071844 cellular component assembly at cellular level
1.58 4.24e-02 GO:0006325 chromatin organization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.14 1.22e-11 GO:0043229 intracellular organelle
1.14 1.68e-11 GO:0043226 organelle
1.11 4.83e-11 GO:0005622 intracellular
1.23 6.76e-11 GO:0005634 nucleus
1.11 2.54e-10 GO:0044424 intracellular part
1.14 4.50e-09 GO:0043231 intracellular membrane-bounded organelle
1.14 4.61e-09 GO:0043227 membrane-bounded organelle
1.29 4.76e-04 GO:0005829 cytosol
2.83 2.60e-03 GO:0000786 nucleosome
1.14 3.36e-03 GO:0044422 organelle part
1.13 4.96e-03 GO:0044446 intracellular organelle part
1.03 5.84e-03 GO:0044464 cell part
1.03 6.05e-03 GO:0005623 cell
2.32 8.41e-03 GO:0032993 protein-DNA complex
1.09 1.11e-02 GO:0005737 cytoplasm
1.79 1.22e-02 GO:0000785 chromatin
1.50 1.28e-02 GO:0005694 chromosome
1.55 1.61e-02 GO:0044427 chromosomal part
1.28 1.91e-02 GO:0005856 cytoskeleton
1.19 3.28e-02 GO:0043228 non-membrane-bounded organelle
1.19 3.28e-02 GO:0043232 intracellular non-membrane-bounded organelle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.06 1.12e-02 GO:0005488 binding