Motif ID: GFI1B.p2

Z-value: 1.130


Transcription factors associated with GFI1B.p2:

Gene SymbolEntrez IDGene Name
GFI1B 8328 growth factor independent 1B transcription repressor



Activity profile for motif GFI1B.p2.

activity profile for motif GFI1B.p2


Sorted Z-values histogram for motif GFI1B.p2

Sorted Z-values for motif GFI1B.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1B.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_67628763 1.563 SOX9
SRY (sex determining region Y)-box 9
chr17_+_67628772 1.383 SOX9
SRY (sex determining region Y)-box 9
chr9_+_676640 1.364


chr2_-_142605010 1.279 LRP1B
low density lipoprotein receptor-related protein 1B
chr17_-_67628523 1.173 FLJ37644
hypothetical LOC400618
chr3_-_188936941 1.146 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr17_+_38306339 1.086 NM_000151
G6PC
glucose-6-phosphatase, catalytic subunit
chr12_-_28016182 0.918 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr17_-_70901303 0.897 GRB2
growth factor receptor-bound protein 2
chr22_+_38903825 0.846 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr6_+_154373323 0.837 NM_001145279
NM_001145280
NM_001145281
OPRM1


opioid receptor, mu 1


chr1_+_216585298 0.764 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr3_+_134976965 0.757 TF
transferrin
chr17_+_67628749 0.729 NM_000346
SOX9
SRY (sex determining region Y)-box 9
chr2_+_204440753 0.715 NM_001037631
NM_005214
CTLA4

cytotoxic T-lymphocyte-associated protein 4

chr22_+_27779877 0.709 ZNRF3
zinc and ring finger 3
chr2_-_189752575 0.690 NM_000393
COL5A2
collagen, type V, alpha 2
chr18_+_53863865 0.642 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr6_-_161614962 0.632 NM_020133
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr1_-_7998265 0.625 ERRFI1
ERBB receptor feedback inhibitor 1
chr4_+_166468266 0.609 NM_001017369
NM_006745
SC4MOL

sterol-C4-methyl oxidase-like

chr11_-_102100833 0.581 NM_002424
MMP8
matrix metallopeptidase 8 (neutrophil collagenase)
chr19_-_4509471 0.573 NM_032108
SEMA6B
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr16_+_8714687 0.572 ABAT
4-aminobutyrate aminotransferase
chr14_+_22859236 0.554 NM_004643
PABPN1
poly(A) binding protein, nuclear 1
chr17_-_9870292 0.554 NM_001130831
GAS7
growth arrest-specific 7
chr5_-_146441184 0.553 NM_181677
NM_181678
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr16_+_8714326 0.549 NM_000663
ABAT
4-aminobutyrate aminotransferase
chr20_+_186376 0.521 NM_207469
DEFB132
defensin, beta 132
chr6_-_31756119 0.503 NM_025262
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr5_+_66160359 0.492 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chrX_+_57635165 0.486 ZXDB
zinc finger, X-linked, duplicated B
chr2_+_176695658 0.476 NM_014213
HOXD9
homeobox D9
chr20_-_51633042 0.473 NM_006526
ZNF217
zinc finger protein 217
chr5_+_109052945 0.471 MAN2A1
mannosidase, alpha, class 2A, member 1
chr5_+_109053034 0.465 NM_002372
MAN2A1
mannosidase, alpha, class 2A, member 1
chr6_-_166960649 0.461 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr2_-_156897286 0.441 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr2_-_158162271 0.437 NM_001111031
ACVR1C
activin A receptor, type IC
chr14_+_19761708 0.436 NM_001004480
OR11H6
olfactory receptor, family 11, subfamily H, member 6
chr5_+_109052984 0.427


chr6_+_43846155 0.427 VEGFA
vascular endothelial growth factor A
chr7_-_113346284 0.420 NM_002711
PPP1R3A
protein phosphatase 1, regulatory (inhibitor) subunit 3A
chr6_-_166960690 0.413 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr14_-_19572756 0.408 NM_001004714
OR4K13
olfactory receptor, family 4, subfamily K, member 13
chr9_-_27287106 0.402 NM_001161585
NM_020641
C9orf11

chromosome 9 open reading frame 11

chr7_-_115458010 0.393 NM_001018058
NM_012252
TFEC

transcription factor EC

chr7_-_115458047 0.391 TFEC
transcription factor EC
chr14_-_23117833 0.387 NM_001146028
NM_032452
JPH4

junctophilin 4

chr7_-_115458064 0.370 TFEC
transcription factor EC
chr12_-_7709734 0.365 NM_001644
APOBEC1
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
chr3_-_168674502 0.361 NM_006217
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr3_-_192063158 0.360 NM_001146686
GEMC1
geminin coiled-coil domain-containing protein 1
chr1_+_61642287 0.359 NFIA
nuclear factor I/A
chr1_-_177378801 0.353 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr6_+_152168500 0.342 NM_001122741
ESR1
estrogen receptor 1
chr17_-_73694669 0.342 NM_003258
TK1
thymidine kinase 1, soluble
chr17_+_11864841 0.338 NM_003010
MAP2K4
mitogen-activated protein kinase kinase 4
chr14_-_23117614 0.337 JPH4
junctophilin 4
chr2_-_69033515 0.336 NM_182536
GKN2
gastrokine 2
chr6_+_43846372 0.333 VEGFA
vascular endothelial growth factor A
chr9_-_106407728 0.328 NM_001004481
OR13C2
olfactory receptor, family 13, subfamily C, member 2
chr3_-_188935363 0.324 NM_001134738
BCL6
B-cell CLL/lymphoma 6
chr2_+_207512522 0.319 NM_173077
CPO
carboxypeptidase O
chr2_+_132001922 0.310 NM_138770
CCDC74A
coiled-coil domain containing 74A
chrX_+_119622570 0.309 NM_001137554
MCTS1
malignant T cell amplified sequence 1
chrX_+_150653873 0.306 NM_005140
CNGA2
cyclic nucleotide gated channel alpha 2
chr15_+_60146467 0.300 NM_207322
C2CD4A
C2 calcium-dependent domain containing 4A
chr1_+_161027115 0.299 NM_016371
HSD17B7
hydroxysteroid (17-beta) dehydrogenase 7
chr18_+_30327243 0.291 NM_001198945
NM_001392
NM_032975
NM_032979
DTNA



dystrobrevin, alpha



chrX_-_57953578 0.289 NM_007156
ZXDA
zinc finger, X-linked, duplicated A
chr2_+_170370290 0.288 SSB
Sjogren syndrome antigen B (autoantigen La)
chr18_+_30327341 0.281 DTNA
dystrobrevin, alpha
chr14_-_23117268 0.278 JPH4
junctophilin 4
chr12_-_22378833 0.276 NM_003034
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr19_+_50141068 0.275 NM_000483
APOC2
apolipoprotein C-II
chr20_-_33706532 0.272 RBM12
RNA binding motif protein 12
chr14_+_38805251 0.272 NM_203356
CTAGE5
CTAGE family, member 5
chr12_+_68028407 0.271 LYZ
lysozyme
chr18_+_3441589 0.268 NM_170695
NM_173210
TGIF1

TGFB-induced factor homeobox 1

chr20_+_55569542 0.267 NM_002591
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr7_+_134483305 0.261 NM_018295
TMEM140
transmembrane protein 140
chr6_-_74284522 0.259 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr14_+_57834962 0.259 NM_002892
NM_023000
NM_023001
ARID4A


AT rich interactive domain 4A (RBP1-like)


chr9_+_104797413 0.257 NM_001340
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr12_+_119617060 0.248


chr1_+_103898844 0.248 NM_020978
AMY2B
amylase, alpha 2B (pancreatic)
chr5_-_22889487 0.246 NM_004061
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr4_-_77163609 0.246 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr7_-_81910956 0.246 NM_000722
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr3_-_113842652 0.243 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chr2_-_104834344 0.243 LOC100506421
hypothetical LOC100506421
chr22_+_36533845 0.239 NM_001171690
NM_014291
GCAT

glycine C-acetyltransferase

chr14_-_57834558 0.239 FLJ31306
hypothetical LOC379025
chr2_+_162908828 0.238 NM_012198
GCA
grancalcin, EF-hand calcium binding protein
chr11_+_111551417 0.237 NM_031938
BCO2
beta-carotene oxygenase 2
chr5_-_22889192 0.236 CDH12
cadherin 12, type 2 (N-cadherin 2)
chr2_+_238372126 0.235 NM_001080504
RBM44
RNA binding motif protein 44
chr11_-_35503720 0.235 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr3_-_113842237 0.234 CCDC80
coiled-coil domain containing 80
chr12_-_242255 0.232 NM_001190997
NM_016615
SLC6A13

solute carrier family 6 (neurotransmitter transporter, GABA), member 13

chr8_-_16094591 0.228 NM_002445
NM_138715
NM_138716
MSR1


macrophage scavenger receptor 1


chr3_-_113842255 0.226 CCDC80
coiled-coil domain containing 80
chr3_-_113842350 0.224 CCDC80
coiled-coil domain containing 80
chrX_+_147608302 0.222 NM_001170628
AFF2
AF4/FMR2 family, member 2
chr20_+_31717964 0.221 NM_001024675
C20orf134
chromosome 20 open reading frame 134
chr6_+_88026338 0.220 ZNF292
zinc finger protein 292
chr12_+_18782307 0.219 NM_033328
CAPZA3
capping protein (actin filament) muscle Z-line, alpha 3
chr10_+_69314347 0.217 NM_012238
SIRT1
sirtuin 1
chr9_+_12683385 0.212 NM_000550
TYRP1
tyrosinase-related protein 1
chr19_-_59476734 0.207 NM_001080978
NM_005874
LILRB2

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2

chr20_-_56859352 0.207 GNAS-AS1
GNAS antisense RNA 1 (non-protein coding)
chr9_+_2707525 0.206 NM_133497
KCNV2
potassium channel, subfamily V, member 2
chr7_-_81910740 0.200 CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr14_-_36121536 0.200 NM_014360
NKX2-8
NK2 homeobox 8
chrX_+_119621933 0.198 MCTS1
malignant T cell amplified sequence 1
chr14_+_57835028 0.196 ARID4A
AT rich interactive domain 4A (RBP1-like)
chr12_+_94776901 0.196 SNRPF
small nuclear ribonucleoprotein polypeptide F
chr15_-_81744469 0.195 NM_001717
BNC1
basonuclin 1
chr6_-_144370947 0.195 PLAGL1
pleiomorphic adenoma gene-like 1
chr7_+_18515440 0.194 HDAC9
histone deacetylase 9
chr2_+_85676347 0.194 NM_016494
RNF181
ring finger protein 181
chr11_-_35235325 0.191 SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr8_-_17624304 0.190 NM_001166393
MTUS1
microtubule associated tumor suppressor 1
chr16_+_82544327 0.188 NM_182981
OSGIN1
oxidative stress induced growth inhibitor 1
chr12_+_52960745 0.187 NM_002136
NM_031157
HNRNPA1

heterogeneous nuclear ribonucleoprotein A1

chr4_-_39199527 0.187 UGDH
UDP-glucose 6-dehydrogenase
chr17_-_37983175 0.183 NM_013290
NM_016556
PSMC3IP

PSMC3 interacting protein

chr16_+_28798735 0.180 ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr11_+_65023556 0.176


chr3_-_121295663 0.176 NM_001146156
NM_002093
GSK3B

glycogen synthase kinase 3 beta

chr7_+_18515488 0.175 HDAC9
histone deacetylase 9
chr16_+_15651583 0.173 NM_017668
NDE1
nudE nuclear distribution gene E homolog 1 (A. nidulans)
chr2_+_176737050 0.173 NM_006898
HOXD3
homeobox D3
chr17_-_39630951 0.173 NM_001098833
NM_020218
ATXN7L3

ataxin 7-like 3

chr2_+_100453375 0.171 NM_001011717
NMS
neuromedin S
chr3_+_48482213 0.170 NM_016381
NM_033629
TREX1

three prime repair exonuclease 1

chr17_+_73694992 0.168 NM_001010982
NM_001145526
AFMID

arylformamidase

chr6_+_53991672 0.167 NM_138569
C6orf142
chromosome 6 open reading frame 142
chr4_+_119825983 0.167 NM_020961
METTL14
methyltransferase like 14
chrX_+_57634993 0.167 NM_007157
ZXDB
zinc finger, X-linked, duplicated B
chr2_+_85696791 0.163 NM_006590
USP39
ubiquitin specific peptidase 39
chr22_+_27498679 0.162 CCDC117
coiled-coil domain containing 117
chr11_-_8849485 0.162 ST5
suppression of tumorigenicity 5
chr4_+_166097579 0.162 C4orf39
chromosome 4 open reading frame 39
chr20_-_33783409 0.161 RBM39
RNA binding motif protein 39
chr3_-_64186151 0.160 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr2_+_85696818 0.160 USP39
ubiquitin specific peptidase 39
chr6_-_116973465 0.158 NM_001139444
BET3L
BET3 like (S. cerevisiae)
chr2_+_85696797 0.158 USP39
ubiquitin specific peptidase 39
chr12_+_52960798 0.157 HNRNPA1L2
HNRNPA1
HNRNPA1P10
heterogeneous nuclear ribonucleoprotein A1-like 2
heterogeneous nuclear ribonucleoprotein A1
heterogeneous nuclear ribonucleoprotein A1 pseudogene 10
chr1_+_50348052 0.156 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr2_+_66516196 0.154 MEIS1
Meis homeobox 1
chr2_-_202215593 0.152 NM_152388
ALS2CR4
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4
chr6_-_119137923 0.152 NM_001178035
C6orf204
chromosome 6 open reading frame 204
chr19_+_47416338 0.151 ZNF526
zinc finger protein 526
chr1_+_148603769 0.151 RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr16_+_52037186 0.151 RBL2
retinoblastoma-like 2 (p130)
chr8_-_16094518 0.151 MSR1
macrophage scavenger receptor 1
chr6_+_132933153 0.149 NM_175067
TAAR6
trace amine associated receptor 6
chr5_-_88215034 0.147 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr1_-_188713324 0.147 NM_199051
FAM5C
family with sequence similarity 5, member C
chr2_-_164300758 0.146 NM_018086
FIGN
fidgetin
chr12_+_94776836 0.146 NM_003095
SNRPF
small nuclear ribonucleoprotein polypeptide F
chr1_+_107485071 0.146 NTNG1
netrin G1
chr8_-_19584373 0.145 NM_018371
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr1_+_101475149 0.145 S1PR1
sphingosine-1-phosphate receptor 1
chr2_+_234245243 0.145 NM_021027
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr19_+_47416271 0.144 NM_133444
ZNF526
zinc finger protein 526
chr4_-_186537145 0.144 NM_018409
LRP2BP
LRP2 binding protein
chr4_-_175986952 0.143 NM_001042543
NM_006529
GLRA3

glycine receptor, alpha 3

chr6_+_43136159 0.141 NM_201522
KLC4
kinesin light chain 4
chr2_-_20375497 0.141 PUM2
pumilio homolog 2 (Drosophila)
chr2_+_85696758 0.140 USP39
ubiquitin specific peptidase 39
chr14_+_22422270 0.139 NM_173527
REM2
RAS (RAD and GEM)-like GTP binding 2
chr12_-_10173947 0.139 NM_022570
NM_197947
NM_197948
NM_197949
NM_197950
NM_197954
CLEC7A





C-type lectin domain family 7, member A





chr15_-_64582049 0.139 RPL4
ribosomal protein L4
chr17_-_35327318 0.138 NM_018530
GSDMB
gasdermin B
chr1_+_152229861 0.138 NM_001030
RPS27
ribosomal protein S27
chr2_+_162908869 0.138 GCA
grancalcin, EF-hand calcium binding protein
chr19_+_45794895 0.138 NM_001042544
LTBP4
latent transforming growth factor beta binding protein 4
chr17_+_20712337 0.135


chr5_+_173405343 0.135 HMP19
HMP19 protein
chr8_-_39814860 0.135 NM_001464
ADAM2
ADAM metallopeptidase domain 2
chr3_-_123584747 0.134 NM_001017928
CCDC58
coiled-coil domain containing 58
chr11_-_102219450 0.134 NM_002422
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr3_-_113842553 0.134 CCDC80
coiled-coil domain containing 80
chrX_+_146941222 0.133 FTH1P8
ferritin, heavy polypeptide 1 pseudogene 8
chr12_-_69434330 0.132 PTPRR
protein tyrosine phosphatase, receptor type, R
chr2_+_102744921 0.131 NM_144632
TMEM182
transmembrane protein 182
chr11_+_118269310 0.131 NM_032966
CXCR5
chemokine (C-X-C motif) receptor 5
chr2_+_233099113 0.129 NM_000751
CHRND
cholinergic receptor, nicotinic, delta
chr4_-_187114863 0.129 NM_021069
SORBS2
sorbin and SH3 domain containing 2
chr17_+_24394281 0.129 PIPOX
pipecolic acid oxidase
chr16_-_54466709 0.129 NM_001143685
NM_145024
CES5A

carboxylesterase 5A

chr3_+_68136056 0.128 NM_213609
FAM19A1
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
chr1_-_197173159 0.126 LOC100131234
familial acute myelogenous leukemia related factor
chr20_-_44151924 0.125 NCOA5
nuclear receptor coactivator 5
chr14_-_106149623 0.125


chr14_+_22059174 0.124



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
4.89 2.18e-02 GO:0034754 cellular hormone metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.50 2.00e-02 GO:0005576 extracellular region

Nothing significant found in function category.