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• Activity deltas table
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Motif ID: GTF2I.p2

Z-value: 1.960

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chrX_+_138060	3.237	NM_018390	PLCXD1	phosphatidylinositol-specific phospholipase C, X domain containing 1
chr9_+_132961683	2.299	NM_001185095 NM_001185096 NM_031426	AIF1L	allograft inflammatory factor 1-like
chr5_+_139008209	2.255	NM_016463	CXXC5	CXXC finger protein 5
chr9_+_132961723	2.209		AIF1L	allograft inflammatory factor 1-like
chr16_+_84202515	2.115	NM_001134473	KIAA0182	KIAA0182
chr5_+_139008667	1.812		CXXC5	CXXC finger protein 5
chr18_+_41659542	1.810	NM_213602	SIGLEC15	sialic acid binding Ig-like lectin 15
chr17_+_7682355	1.590
chr5_+_36912595	1.473	NM_015384 NM_133433	NIPBL	Nipped-B homolog (Drosophila)
chr16_-_71650034	1.451	NM_001164766	ZFHX3	zinc finger homeobox 3
chr5_+_139008052	1.400		CXXC5	CXXC finger protein 5
chr6_+_149680747	1.331		TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr7_+_5289079	1.310	NM_001040661 NM_153247	SLC29A4	solute carrier family 29 (nucleoside transporters), member 4
chr5_+_139008091	1.279		CXXC5	CXXC finger protein 5
chr5_-_36912487	1.210		LOC646719	hypothetical LOC646719
chr5_+_139008139	1.188		CXXC5	CXXC finger protein 5
chr17_-_34157962	1.185	NM_007144	PCGF2	polycomb group ring finger 2
chr5_+_36912656	1.175		NIPBL	Nipped-B homolog (Drosophila)
chr1_+_224317044	1.148		H3F3A LOC440926	H3 histone, family 3A H3 histone, family 3A pseudogene
chr1_+_224317030	1.145		H3F3A	H3 histone, family 3A
chr1_+_224317062	1.142		H3F3A LOC440926	H3 histone, family 3A H3 histone, family 3A pseudogene
chr1_+_224317056	1.116		H3F3A LOC440926	H3 histone, family 3A H3 histone, family 3A pseudogene
chr16_-_29817841	1.097	NM_001114099 NM_001114100 NM_012410 NM_201575	SEZ6L2	seizure related 6 homolog (mouse)-like 2
chr6_+_37245860	1.037	NM_002648	PIM1	pim-1 oncogene
chr6_+_43846735	0.970		VEGFA	vascular endothelial growth factor A
chr6_+_33046706	0.964		BRD2	bromodomain containing 2
chr20_+_30410447	0.955		ASXL1	additional sex combs like 1 (Drosophila)
chr1_+_224317036	0.950	NM_002107	H3F3A	H3 histone, family 3A
chr6_-_16869579	0.930	NM_000332 NM_001128164	ATXN1	ataxin 1
chr1_+_165866127	0.920		RCSD1	RCSD domain containing 1
chr16_+_73590739	0.904		ZNRF1	zinc and ring finger 1
chr20_+_60906605	0.893	NM_007346	OGFR	opioid growth factor receptor
chrX_+_122923279	0.853		STAG2	stromal antigen 2
chr6_-_32265489	0.853	NM_002586	PBX2	pre-B-cell leukemia homeobox 2
chr10_+_114699953	0.849	NM_001146274 NM_001146283 NM_001146284 NM_001146285 NM_001146286 NM_001198525 NM_001198526 NM_001198527 NM_001198528 NM_001198529 NM_001198530 NM_001198531 NM_030756	TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)
chr15_-_49174107	0.841		TNFAIP8L3	tumor necrosis factor, alpha-induced protein 8-like 3
chr1_-_20685314	0.830	NM_018584	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr1_+_29113589	0.816	NM_001166006	EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr7_+_149707338	0.814	NM_173680	ZNF775	zinc finger protein 775
chr6_-_42527760	0.813	NM_033502	TRERF1	transcriptional regulating factor 1
chr15_-_73531082	0.813	NM_001145358	SIN3A	SIN3 homolog A, transcription regulator (yeast)
chr6_+_33046636	0.804	NM_001113182	BRD2	bromodomain containing 2
chr19_-_59676153	0.795	NM_145057	CDC42EP5	CDC42 effector protein (Rho GTPase binding) 5
chr11_-_56846246	0.794		TNKS1BP1	tankyrase 1 binding protein 1, 182kDa
chr2_-_19421852	0.783	NM_145260	OSR1	odd-skipped related 1 (Drosophila)
chr2_+_218972963	0.780	NM_182642	CTDSP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr2_+_218972721	0.780	NM_021198	CTDSP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr1_-_24307514	0.779		MYOM3	myomesin family, member 3
chr19_+_45797413	0.769		LTBP4	latent transforming growth factor beta binding protein 4
chr5_+_92944680	0.759	NM_005654	NR2F1	nuclear receptor subfamily 2, group F, member 1
chr22_-_19180075	0.758	NM_032775	KLHL22	kelch-like 22 (Drosophila)
chr20_-_30636535	0.758		LOC284804	hypothetical protein LOC284804
chr22_+_21852551	0.746	NM_004327 NM_021574	BCR	breakpoint cluster region
chr1_+_26895108	0.744	NM_006015 NM_139135	ARID1A	AT rich interactive domain 1A (SWI-like)
chr20_+_29870836	0.743	NM_033118	MYLK2	myosin light chain kinase 2
chr12_+_110328126	0.725	NM_005475	SH2B3	SH2B adaptor protein 3
chr15_-_73530829	0.725	NM_015477	SIN3A	SIN3 homolog A, transcription regulator (yeast)
chrX_+_122923236	0.723	NM_001042750 NM_001042751 NM_006603	STAG2	stromal antigen 2
chr1_+_945399	0.719
chr1_+_199884072	0.718	NM_020443	NAV1	neuron navigator 1
chr16_+_73590419	0.716		ZNRF1	zinc and ring finger 1
chr16_+_73590470	0.715		ZNRF1	zinc and ring finger 1
chr9_-_130006309	0.711	NM_001131015 NM_012127	CIZ1	CDKN1A interacting zinc finger protein 1
chr16_+_84204424	0.710	NM_014615	KIAA0182	KIAA0182
chr19_+_59061422	0.707	NM_001020820	MYADM	myeloid-associated differentiation marker
chr6_+_149681128	0.704	NM_015093	TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr11_-_72698050	0.703		LOC100287837	hypothetical protein LOC100287837
chr1_-_20684858	0.703		CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr10_+_22650145	0.702		BMI1	BMI1 polycomb ring finger oncogene
chr1_+_945331	0.698	NM_198576	AGRN	agrin
chr16_+_73590375	0.696	NM_032268	ZNRF1	zinc and ring finger 1
chr19_+_48549664	0.696	NM_020406	CD177	CD177 molecule
chr7_-_105304159	0.693	NM_020725 NM_152749	ATXN7L1	ataxin 7-like 1
chr6_+_33045070	0.691
chr2_+_54536780	0.681	NM_003128	SPTBN1	spectrin, beta, non-erythrocytic 1
chr17_-_7083321	0.677	NM_024297	PHF23	PHD finger protein 23
chr20_-_61574259	0.676	NM_004518 NM_172106 NM_172107 NM_172108 NM_172109	KCNQ2	potassium voltage-gated channel, KQT-like subfamily, member 2
chr16_+_29726962	0.676		MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)
chr12_+_47495567	0.667		CACNB3	calcium channel, voltage-dependent, beta 3 subunit
chr1_+_110555433	0.666		KCNC4	potassium voltage-gated channel, Shaw-related subfamily, member 4
chr2_+_232281470	0.665	NM_001099285 NM_002823	PTMA	prothymosin, alpha
chr3_+_4996096	0.663	NM_003670	BHLHE40	basic helix-loop-helix family, member e40
chr6_+_33486750	0.659	NM_002636 NM_024165	PHF1	PHD finger protein 1
chr6_+_1335067	0.655	NM_001452	FOXF2	forkhead box F2
chr16_-_29949637	0.654	NM_031478	FAM57B	family with sequence similarity 57, member B
chr1_+_202308814	0.650	NM_005686	SOX13	SRY (sex determining region Y)-box 13
chr15_+_41597097	0.648	NM_002373	MAP1A	microtubule-associated protein 1A
chr12_-_52179462	0.645	NM_001193511 NM_006301	MAP3K12	mitogen-activated protein kinase kinase kinase 12
chr1_+_203740306	0.643	NM_002596 NM_212502 NM_212503	CDK18	cyclin-dependent kinase 18
chr7_+_73506333	0.642	NM_005685	GTF2IRD1	GTF2I repeat domain containing 1
chr5_-_81082614	0.639		SSBP2	single-stranded DNA binding protein 2
chr1_+_165865953	0.636	NM_052862	RCSD1	RCSD domain containing 1
chr1_-_8406288	0.635	NM_001042682	RERE	arginine-glutamic acid dipeptide (RE) repeats
chr7_+_105304445	0.631		LOC100506768 CDHR3	hypothetical LOC100506768 cadherin-related family member 3
chr19_-_55763091	0.629	NM_001080457	LRRC4B	leucine rich repeat containing 4B
chr2_+_149118791	0.628		EPC2	enhancer of polycomb homolog 2 (Drosophila)
chr2_+_127892459	0.627	NM_000312	PROC	protein C (inactivator of coagulation factors Va and VIIIa)
chr6_+_41622111	0.627	NM_001012426 NM_001012427 NM_138457	FOXP4	forkhead box P4
chr6_+_41622267	0.626		FOXP4	forkhead box P4
chr4_+_129950222	0.625	NM_024900 NM_199320	PHF17	PHD finger protein 17
chr18_+_44319365	0.623	NM_001142397 NM_014772	CTIF	CBP80/20-dependent translation initiation factor
chr17_+_34115383	0.621	NM_005937	MLLT6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr16_+_24648446	0.618	NM_014494	TNRC6A	trinucleotide repeat containing 6A
chr2_+_127892489	0.617		PROC	protein C (inactivator of coagulation factors Va and VIIIa)
chr16_-_29818334	0.615		SEZ6L2	seizure related 6 homolog (mouse)-like 2
chr21_+_42946719	0.611	NM_001001567 NM_001001568 NM_001001569 NM_001001570 NM_001001571 NM_001001572 NM_001001573 NM_001001574 NM_001001575 NM_001001576 NM_001001577 NM_001001578 NM_001001579 NM_001001580 NM_001001581 NM_001001582 NM_001001583 NM_001001584 NM_001001585 NM_002606	PDE9A	phosphodiesterase 9A
chr7_+_73506172	0.610		GTF2IRD1	GTF2I repeat domain containing 1
chr15_+_88345612	0.609	NM_198526	ZNF710	zinc finger protein 710
chr16_-_20819061	0.604	NM_173475	DCUN1D3	DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr17_+_53515725	0.603	NM_080677	DYNLL2	dynein, light chain, LC8-type 2
chr1_+_167342493	0.603	NM_001677	ATP1B1	ATPase, Na+/K+ transporting, beta 1 polypeptide
chr5_+_10406829	0.602		MARCH6	membrane-associated ring finger (C3HC4) 6
chr1_+_199884152	0.601		NAV1	neuron navigator 1
chr16_+_49139694	0.598	NM_033119	NKD1	naked cuticle homolog 1 (Drosophila)
chr6_+_43846155	0.596		VEGFA	vascular endothelial growth factor A
chr12_-_113606322	0.595	NM_005996 NM_016569	TBX3	T-box 3
chr16_+_29726931	0.593		MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)
chr5_+_135392482	0.590	NM_000358	TGFBI	transforming growth factor, beta-induced, 68kDa
chr5_+_148766632	0.588		LOC728264	hypothetical LOC728264
chr17_-_43977273	0.586	NM_002145	HOXB2	homeobox B2
chr3_+_38470782	0.582	NM_001106	ACVR2B	activin A receptor, type IIB
chr20_+_51023159	0.582		TSHZ2	teashirt zinc finger homeobox 2
chr5_+_137701122	0.580	NM_001135647	FAM53C	family with sequence similarity 53, member C
chr2_+_8739563	0.577	NM_002166	ID2	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr19_+_1226510	0.574	NM_017914	C19orf24	chromosome 19 open reading frame 24
chr19_-_55914837	0.566
chr17_+_19255083	0.565	NM_007148	RNF112	ring finger protein 112
chr2_+_220200530	0.562	NM_005070 NM_201574	SLC4A3	solute carrier family 4, anion exchanger, member 3
chr1_+_6596331	0.561	NM_153812	PHF13	PHD finger protein 13
chr1_+_201711505	0.560	NM_002725 NM_201348	PRELP	proline/arginine-rich end leucine-rich repeat protein
chr7_+_73506047	0.558	NM_016328	GTF2IRD1	GTF2I repeat domain containing 1
chr4_+_48038095	0.548		SLAIN2	SLAIN motif family, member 2
chr1_+_165456572	0.546	NM_001198786 NM_002697	POU2F1	POU class 2 homeobox 1
chr12_-_24606616	0.541	NM_152989	SOX5	SRY (sex determining region Y)-box 5
chr1_-_6468600	0.541	NM_001042665	PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr5_+_56505608	0.539		GPBP1	GC-rich promoter binding protein 1
chr20_-_61462960	0.537	NM_000744	CHRNA4	cholinergic receptor, nicotinic, alpha 4
chr2_-_148494732	0.535	NM_001190882 NM_001190879 NM_002552 NM_001190881 NM_181741	ORC4	origin recognition complex, subunit 4
chr4_-_185632610	0.532	NM_002199	IRF2	interferon regulatory factor 2
chr3_+_46898673	0.531	NM_001184744	PTH1R	parathyroid hormone 1 receptor
chr1_+_116718011	0.531	NM_001160233	ATP1A1	ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr15_+_91244563	0.530		CHD2	chromodomain helicase DNA binding protein 2
chr1_+_153241665	0.529	NM_015872	ZBTB7B	zinc finger and BTB domain containing 7B
chr1_+_87567136	0.529		LMO4	LIM domain only 4
chr6_-_143307976	0.526	NM_006734	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2
chr1_-_166172901	0.526	NM_001143674	BRP44	brain protein 44
chr3_+_192529567	0.522	NM_174908 NM_178335	CCDC50	coiled-coil domain containing 50
chr3_+_38182120	0.520		OXSR1	oxidative-stress responsive 1
chr15_+_91244422	0.520	NM_001042572 NM_001271	CHD2	chromodomain helicase DNA binding protein 2
chr1_+_6226838	0.516	NM_001024598	HES3	hairy and enhancer of split 3 (Drosophila)
chr10_+_22649977	0.512	NM_005180	BMI1	BMI1 polycomb ring finger oncogene
chr7_+_104441730	0.512	NM_018682 NM_182931	MLL5	myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr1_+_945472	0.511		AGRN	agrin
chr6_+_7053863	0.511		RREB1	ras responsive element binding protein 1
chr12_+_92295738	0.511	NM_019094 NM_199040	NUDT4 NUDT4P1	nudix (nucleoside diphosphate linked moiety X)-type motif 4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 pseudogene 1
chr16_-_3008162	0.511	NM_021195	CLDN6	claudin 6
chr2_+_86521999	0.508	NM_001146688	KDM3A	lysine (K)-specific demethylase 3A
chr9_-_132804057	0.508	NM_032843	FIBCD1	fibrinogen C domain containing 1
chr7_+_7974941	0.507	NM_138426	GLCCI1	glucocorticoid induced transcript 1
chr5_-_10406690	0.504
chr2_+_86521781	0.503	NM_018433	KDM3A	lysine (K)-specific demethylase 3A
chr1_+_203740391	0.502		CDK18	cyclin-dependent kinase 18
chr8_+_27547379	0.501	NM_016240 NM_182826	SCARA3	scavenger receptor class A, member 3
chr3_+_9414290	0.498	NM_001080517	SETD5	SET domain containing 5
chr1_-_202595666	0.498	NM_014935	PLEKHA6	pleckstrin homology domain containing, family A member 6
chr19_+_3175734	0.497		CELF5	CUGBP, Elav-like family member 5
chr1_+_116717552	0.496		ATP1A1	ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr6_+_44352443	0.492		TMEM151B	transmembrane protein 151B
chr2_+_86521939	0.489		KDM3A	lysine (K)-specific demethylase 3A
chr1_+_167342149	0.487		ATP1B1	ATPase, Na+/K+ transporting, beta 1 polypeptide
chr7_-_150604752	0.486	NM_001003802	SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr14_-_104507862	0.486		AHNAK2	AHNAK nucleoprotein 2
chr7_+_97748959	0.486		BRI3	brain protein I3
chr5_+_135392624	0.485		TGFBI	transforming growth factor, beta-induced, 68kDa
chr2_+_177785667	0.485	NM_194247	HNRNPA3P1 HNRNPA3	heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 heterogeneous nuclear ribonucleoprotein A3
chr3_+_23961739	0.484	NM_005126	NR1D2	nuclear receptor subfamily 1, group D, member 2
chr17_+_34279781	0.484		LASP1	LIM and SH3 protein 1
chr3_+_42675841	0.481		ZBTB47	zinc finger and BTB domain containing 47
chr6_+_43846372	0.479		VEGFA	vascular endothelial growth factor A
chr12_+_55769189	0.479		NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)
chr2_-_26395420	0.479	NM_001145168 NM_001145169	GPR113	G protein-coupled receptor 113
chr9_-_34579679	0.474	NM_001842 NM_147164	CNTFR	ciliary neurotrophic factor receptor
chr20_+_60558104	0.466	NM_178463	C20orf166	chromosome 20 open reading frame 166
chr22_-_44751671	0.464	NM_058238	WNT7B	wingless-type MMTV integration site family, member 7B
chr9_-_132803809	0.464		FIBCD1	fibrinogen C domain containing 1
chr14_-_23117833	0.462	NM_001146028 NM_032452	JPH4	junctophilin 4
chr17_-_70901303	0.461		GRB2	growth factor receptor-bound protein 2
chr6_+_89847019	0.461	NM_006813	PNRC1	proline-rich nuclear receptor coactivator 1
chr2_+_149119029	0.460	NM_015630	EPC2	enhancer of polycomb homolog 2 (Drosophila)
chrX_+_128942435	0.459
chr5_+_10406980	0.457
chr1_+_201711578	0.450		PRELP	proline/arginine-rich end leucine-rich repeat protein
chr14_+_20608179	0.450	NM_018071	ARHGEF40	Rho guanine nucleotide exchange factor (GEF) 40
chr1_+_153241858	0.448		ZBTB7B	zinc finger and BTB domain containing 7B
chr21_+_37661728	0.445	NM_101395	DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr15_+_38520594	0.445	NM_014952	BAHD1	bromo adjacent homology domain containing 1
chr1_-_27802947	0.444		AHDC1	AT hook, DNA binding motif, containing 1
chr20_-_61600834	0.444	NM_001958	EEF1A2	eukaryotic translation elongation factor 1 alpha 2
chr11_-_70350292	0.443		SHANK2	SH3 and multiple ankyrin repeat domains 2
chr2_-_227371698	0.443	NM_005544	IRS1	insulin receptor substrate 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.18	2.34e-27	GO:0050789	regulation of biological process
1.19	2.95e-27	GO:0050794	regulation of cellular process
1.17	3.24e-27	GO:0065007	biological regulation
1.30	1.99e-19	GO:0048518	positive regulation of biological process
1.31	1.61e-17	GO:0048522	positive regulation of cellular process
1.31	4.08e-17	GO:0048519	negative regulation of biological process
1.23	1.24e-16	GO:0023052	signaling
1.24	3.70e-16	GO:0060255	regulation of macromolecule metabolic process
1.32	5.76e-16	GO:0048523	negative regulation of cellular process
1.22	7.82e-16	GO:0019222	regulation of metabolic process
1.09	8.08e-16	GO:0009987	cellular process
1.23	1.51e-15	GO:0031323	regulation of cellular metabolic process
1.23	1.18e-14	GO:0080090	regulation of primary metabolic process
1.22	6.07e-13	GO:0007165	signal transduction
1.19	1.23e-12	GO:0051716	cellular response to stimulus
1.38	4.81e-12	GO:0009893	positive regulation of metabolic process
1.38	3.48e-11	GO:0010604	positive regulation of macromolecule metabolic process
1.20	8.22e-11	GO:0007275	multicellular organismal development
1.37	1.14e-10	GO:0031325	positive regulation of cellular metabolic process
1.31	1.28e-10	GO:0023051	regulation of signaling
1.39	1.43e-10	GO:0051246	regulation of protein metabolic process
1.50	1.46e-10	GO:0009719	response to endogenous stimulus
1.33	2.50e-10	GO:0009966	regulation of signal transduction
1.51	5.82e-10	GO:0009725	response to hormone stimulus
1.18	6.21e-10	GO:0032502	developmental process
1.39	9.89e-10	GO:0032268	regulation of cellular protein metabolic process
1.39	1.98e-09	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.22	1.17e-08	GO:0010468	regulation of gene expression
1.21	1.23e-08	GO:0048731	system development
1.16	1.41e-08	GO:0044260	cellular macromolecule metabolic process
1.26	2.41e-08	GO:0048583	regulation of response to stimulus
1.21	2.43e-08	GO:0031326	regulation of cellular biosynthetic process
1.32	2.55e-08	GO:0010033	response to organic substance
1.29	3.64e-08	GO:0009653	anatomical structure morphogenesis
1.22	4.56e-08	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.21	5.17e-08	GO:0009889	regulation of biosynthetic process
1.19	6.49e-08	GO:0048856	anatomical structure development
1.40	7.13e-08	GO:0031399	regulation of protein modification process
1.43	7.98e-08	GO:0019220	regulation of phosphate metabolic process
1.43	7.98e-08	GO:0051174	regulation of phosphorus metabolic process
1.39	1.05e-07	GO:0051128	regulation of cellular component organization
1.36	1.16e-07	GO:0009892	negative regulation of metabolic process
1.14	1.42e-07	GO:0043170	macromolecule metabolic process
1.43	2.34e-07	GO:0042325	regulation of phosphorylation
1.25	2.71e-07	GO:0048513	organ development
1.21	3.22e-07	GO:0010556	regulation of macromolecule biosynthetic process
1.36	4.75e-07	GO:0010605	negative regulation of macromolecule metabolic process
1.19	4.84e-07	GO:0051171	regulation of nitrogen compound metabolic process
1.43	7.62e-07	GO:0001932	regulation of protein phosphorylation
1.42	9.57e-07	GO:0071310	cellular response to organic substance
1.44	9.86e-07	GO:0010629	negative regulation of gene expression
1.29	1.00e-06	GO:0051239	regulation of multicellular organismal process
1.19	1.47e-06	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.35	1.76e-06	GO:0031324	negative regulation of cellular metabolic process
1.43	1.89e-06	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.41	2.17e-06	GO:0010628	positive regulation of gene expression
1.16	2.86e-06	GO:0071840	cellular component organization or biogenesis
1.41	2.96e-06	GO:0010558	negative regulation of macromolecule biosynthetic process
1.11	3.74e-06	GO:0044237	cellular metabolic process
1.37	3.87e-06	GO:0051173	positive regulation of nitrogen compound metabolic process
1.33	3.89e-06	GO:0042127	regulation of cell proliferation
1.47	3.90e-06	GO:0043549	regulation of kinase activity
1.39	4.53e-06	GO:0009890	negative regulation of biosynthetic process
1.16	4.74e-06	GO:0016043	cellular component organization
1.39	6.35e-06	GO:0031327	negative regulation of cellular biosynthetic process
1.47	6.42e-06	GO:0072358	cardiovascular system development
1.47	6.42e-06	GO:0072359	circulatory system development
1.39	7.57e-06	GO:0045595	regulation of cell differentiation
1.37	1.06e-05	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.31	1.08e-05	GO:0007154	cell communication
1.57	1.25e-05	GO:0033674	positive regulation of kinase activity
1.37	1.27e-05	GO:0006468	protein phosphorylation
1.23	1.36e-05	GO:0007166	cell surface receptor linked signaling pathway
1.38	1.52e-05	GO:0009790	embryo development
1.33	1.74e-05	GO:0050793	regulation of developmental process
1.43	1.96e-05	GO:0045892	negative regulation of transcription, DNA-dependent
1.46	2.13e-05	GO:0045859	regulation of protein kinase activity
1.26	2.74e-05	GO:0035556	intracellular signal transduction
1.55	3.00e-05	GO:0051347	positive regulation of transferase activity
1.44	3.16e-05	GO:0051338	regulation of transferase activity
1.54	3.31e-05	GO:0071495	cellular response to endogenous stimulus
1.31	3.37e-05	GO:0032879	regulation of localization
1.39	3.47e-05	GO:0045893	positive regulation of transcription, DNA-dependent
1.33	4.53e-05	GO:0016310	phosphorylation
1.51	5.16e-05	GO:0016568	chromatin modification
1.30	5.24e-05	GO:0006793	phosphorus metabolic process
1.30	5.24e-05	GO:0006796	phosphate metabolic process
1.24	5.93e-05	GO:0007399	nervous system development
1.55	7.10e-05	GO:0045860	positive regulation of protein kinase activity
1.34	7.28e-05	GO:0007267	cell-cell signaling
1.10	7.31e-05	GO:0044238	primary metabolic process
1.19	7.45e-05	GO:0051252	regulation of RNA metabolic process
1.35	7.50e-05	GO:0010557	positive regulation of macromolecule biosynthetic process
1.37	8.18e-05	GO:0051254	positive regulation of RNA metabolic process
1.32	9.55e-05	GO:0031328	positive regulation of cellular biosynthetic process
1.19	1.07e-04	GO:0065008	regulation of biological quality
1.21	1.15e-04	GO:0006464	protein modification process
1.19	1.22e-04	GO:0006355	regulation of transcription, DNA-dependent
1.40	1.28e-04	GO:0051253	negative regulation of RNA metabolic process
1.31	1.32e-04	GO:0006351	transcription, DNA-dependent
1.31	1.35e-04	GO:0022008	neurogenesis
1.55	1.44e-04	GO:0001944	vasculature development
1.19	1.45e-04	GO:0042221	response to chemical stimulus
1.28	1.83e-04	GO:0010646	regulation of cell communication
1.09	1.88e-04	GO:0008152	metabolic process
1.37	1.91e-04	GO:0051172	negative regulation of nitrogen compound metabolic process
1.31	2.53e-04	GO:0009891	positive regulation of biosynthetic process
1.33	2.56e-04	GO:2000026	regulation of multicellular organismal development
1.37	2.68e-04	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.29	2.80e-04	GO:0070887	cellular response to chemical stimulus
1.23	3.22e-04	GO:0065009	regulation of molecular function
1.52	3.76e-04	GO:0032870	cellular response to hormone stimulus
1.54	6.88e-04	GO:0001568	blood vessel development
1.63	7.05e-04	GO:0044087	regulation of cellular component biogenesis
1.19	7.80e-04	GO:0030154	cell differentiation
1.19	7.99e-04	GO:0043412	macromolecule modification
1.17	1.05e-03	GO:0006950	response to stress
1.29	1.10e-03	GO:0008219	cell death
1.68	1.20e-03	GO:0070482	response to oxygen levels
1.42	1.28e-03	GO:0032583	regulation of gene-specific transcription
1.55	1.33e-03	GO:0000165	MAPKKK cascade
1.29	1.49e-03	GO:0009888	tissue development
1.41	1.58e-03	GO:0051094	positive regulation of developmental process
1.33	1.72e-03	GO:0007167	enzyme linked receptor protein signaling pathway
1.29	1.85e-03	GO:0016265	death
1.52	1.90e-03	GO:0048545	response to steroid hormone stimulus
1.16	1.91e-03	GO:0071842	cellular component organization at cellular level
1.40	1.94e-03	GO:0048646	anatomical structure formation involved in morphogenesis
1.49	1.99e-03	GO:0051130	positive regulation of cellular component organization
1.18	2.28e-03	GO:0048869	cellular developmental process
1.48	2.30e-03	GO:0060284	regulation of cell development
1.38	2.37e-03	GO:0019226	transmission of nerve impulse
1.38	2.37e-03	GO:0035637	multicellular organismal signaling
1.16	2.55e-03	GO:0044267	cellular protein metabolic process
1.25	2.56e-03	GO:0010941	regulation of cell death
1.15	2.58e-03	GO:0071841	cellular component organization or biogenesis at cellular level
1.26	2.80e-03	GO:0043067	regulation of programmed cell death
1.40	3.15e-03	GO:0007268	synaptic transmission
1.39	3.23e-03	GO:0008283	cell proliferation
1.28	3.36e-03	GO:0048699	generation of neurons
1.41	3.54e-03	GO:0051247	positive regulation of protein metabolic process
1.28	4.55e-03	GO:0044093	positive regulation of molecular function
1.43	4.59e-03	GO:0048598	embryonic morphogenesis
1.25	4.75e-03	GO:0042981	regulation of apoptosis
1.18	4.75e-03	GO:0010467	gene expression
1.49	4.77e-03	GO:0010608	posttranscriptional regulation of gene expression
1.33	4.77e-03	GO:0009887	organ morphogenesis
1.19	4.86e-03	GO:0016070	RNA metabolic process
1.09	5.40e-03	GO:0050896	response to stimulus
1.54	5.44e-03	GO:0051129	negative regulation of cellular component organization
1.47	5.64e-03	GO:0048729	tissue morphogenesis
1.48	6.14e-03	GO:0071900	regulation of protein serine/threonine kinase activity
1.40	6.24e-03	GO:0007243	intracellular protein kinase cascade
1.40	6.24e-03	GO:0023014	signal transduction via phosphorylation event
1.45	6.70e-03	GO:0033043	regulation of organelle organization
1.44	7.06e-03	GO:0043434	response to peptide hormone stimulus
1.65	8.14e-03	GO:0001666	response to hypoxia
1.35	8.70e-03	GO:0008284	positive regulation of cell proliferation
1.30	9.65e-03	GO:0043085	positive regulation of catalytic activity
1.41	1.15e-02	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.29	1.16e-02	GO:0051049	regulation of transport
1.40	1.21e-02	GO:0010627	regulation of intracellular protein kinase cascade
1.61	1.24e-02	GO:0071902	positive regulation of protein serine/threonine kinase activity
1.75	1.48e-02	GO:0031098	stress-activated protein kinase signaling cascade
1.39	1.72e-02	GO:0007264	small GTPase mediated signal transduction
1.24	1.73e-02	GO:0032774	RNA biosynthetic process
1.36	1.73e-02	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.54	1.84e-02	GO:0043405	regulation of MAP kinase activity
1.91	1.90e-02	GO:0022612	gland morphogenesis
1.22	1.91e-02	GO:0050790	regulation of catalytic activity
1.41	1.96e-02	GO:0007420	brain development
1.35	2.03e-02	GO:0006325	chromatin organization
1.39	2.04e-02	GO:0032270	positive regulation of cellular protein metabolic process
1.39	2.06e-02	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.42	2.18e-02	GO:0045597	positive regulation of cell differentiation
1.40	2.38e-02	GO:0043009	chordate embryonic development
1.13	2.59e-02	GO:0019538	protein metabolic process
1.21	2.60e-02	GO:0002376	immune system process
1.49	2.73e-02	GO:0003002	regionalization
1.31	2.84e-02	GO:0042060	wound healing
1.39	2.86e-02	GO:0009792	embryo development ending in birth or egg hatching
1.51	3.00e-02	GO:0048011	nerve growth factor receptor signaling pathway
1.28	3.01e-02	GO:0006915	apoptosis
1.13	3.18e-02	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.73	3.26e-02	GO:0032970	regulation of actin filament-based process
1.59	3.27e-02	GO:0006936	muscle contraction
1.49	3.32e-02	GO:0048568	embryonic organ development
1.18	3.37e-02	GO:0006996	organelle organization
1.56	3.37e-02	GO:0003012	muscle system process
1.97	3.40e-02	GO:0051494	negative regulation of cytoskeleton organization
1.71	3.70e-02	GO:0000187	activation of MAPK activity
1.54	3.93e-02	GO:0048732	gland development
1.33	4.25e-02	GO:0007599	hemostasis
1.51	4.29e-02	GO:0048514	blood vessel morphogenesis
1.27	4.77e-02	GO:0012501	programmed cell death
1.29	5.00e-02	GO:0051726	regulation of cell cycle
1.09	5.00e-02	GO:0032501	multicellular organismal process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.06	1.09e-08	GO:0044424	intracellular part
1.23	1.41e-08	GO:0005829	cytosol
1.06	1.53e-08	GO:0005622	intracellular
1.80	3.22e-06	GO:0005912	adherens junction
1.11	4.58e-06	GO:0005634	nucleus
1.08	1.24e-05	GO:0005737	cytoplasm
1.71	2.42e-05	GO:0070161	anchoring junction
1.52	5.37e-05	GO:0015629	actin cytoskeleton
1.15	8.10e-05	GO:0043234	protein complex
1.89	8.82e-05	GO:0005925	focal adhesion
1.23	1.72e-04	GO:0005654	nucleoplasm
1.19	1.86e-04	GO:0031981	nuclear lumen
1.28	2.23e-04	GO:0042995	cell projection
1.17	3.59e-04	GO:0044428	nuclear part
1.61	4.38e-04	GO:0030424	axon
1.80	4.48e-04	GO:0030055	cell-substrate junction
1.33	6.34e-04	GO:0030054	cell junction
1.80	6.92e-04	GO:0005924	cell-substrate adherens junction
1.53	7.25e-04	GO:0016323	basolateral plasma membrane
1.38	2.51e-03	GO:0043005	neuron projection
1.05	3.02e-03	GO:0043226	organelle
1.11	3.84e-03	GO:0032991	macromolecular complex
1.15	4.92e-03	GO:0043233	organelle lumen
1.05	5.24e-03	GO:0043229	intracellular organelle
1.25	7.36e-03	GO:0031982	vesicle
1.14	8.41e-03	GO:0070013	intracellular organelle lumen
1.05	1.33e-02	GO:0043227	membrane-bounded organelle
1.52	1.36e-02	GO:0031252	cell leading edge
1.05	1.42e-02	GO:0043231	intracellular membrane-bounded organelle
1.25	1.44e-02	GO:0031988	membrane-bounded vesicle
1.14	1.67e-02	GO:0031974	membrane-enclosed lumen
1.23	3.38e-02	GO:0031410	cytoplasmic vesicle
1.48	3.60e-02	GO:0030425	dendrite
2.60	3.92e-02	GO:0031519	PcG protein complex
1.24	3.95e-02	GO:0016023	cytoplasmic membrane-bounded vesicle
1.16	4.80e-02	GO:0005856	cytoskeleton

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.19	8.56e-33	GO:0005515	protein binding
1.07	8.90e-15	GO:0005488	binding
1.38	5.20e-10	GO:0001071	nucleic acid binding transcription factor activity
1.38	5.20e-10	GO:0003700	sequence-specific DNA binding transcription factor activity
1.32	4.22e-07	GO:0030528	transcription regulator activity
1.37	3.99e-06	GO:0043565	sequence-specific DNA binding
1.35	4.43e-06	GO:0019899	enzyme binding
1.38	9.87e-05	GO:0008092	cytoskeletal protein binding
1.26	4.61e-04	GO:0005102	receptor binding
1.44	1.57e-03	GO:0003779	actin binding
1.37	2.81e-03	GO:0019904	protein domain specific binding
1.42	4.79e-03	GO:0016563	transcription activator activity
1.76	5.22e-03	GO:0005057	receptor signaling protein activity
1.28	2.78e-02	GO:0004672	protein kinase activity
1.79	3.21e-02	GO:0031625	ubiquitin protein ligase binding