Motif ID: HES1.p2

Z-value: 1.487


Transcription factors associated with HES1.p2:

Gene SymbolEntrez IDGene Name
HES1 3280 hairy and enhancer of split 1, (Drosophila)



Activity profile for motif HES1.p2.

activity profile for motif HES1.p2


Sorted Z-values histogram for motif HES1.p2

Sorted Z-values for motif HES1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HES1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_11819364 5.139 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr2_+_113119985 2.354 NM_005415
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr12_+_8741746 2.353 NM_020734
RIMKLB
ribosomal modification protein rimK-like family member B
chr2_+_46779827 2.302 NM_144949
SOCS5
suppressor of cytokine signaling 5
chr14_+_61231795 2.152 NM_001530
NM_181054
HIF1A

hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

chr2_+_182464910 2.089 SSFA2
sperm specific antigen 2
chr3_-_88190737 2.078 NM_001008390
NM_003663
CGGBP1

CGG triplet repeat binding protein 1

chr3_+_112273464 1.925 NM_015480
PVRL3
poliovirus receptor-related 3
chr7_+_93977267 1.897 CASD1
CAS1 domain containing 1
chr17_+_43082273 1.874 NM_002265
KPNB1
karyopherin (importin) beta 1
chr22_+_39817733 1.848 EP300
E1A binding protein p300
chr2_+_181553613 1.824 UBE2E3
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr2_-_225615556 1.761 NM_014689
DOCK10
dedicator of cytokinesis 10
chr2_+_85619802 1.754 MAT2A
methionine adenosyltransferase II, alpha
chr5_+_63497408 1.743 NM_001113561
NM_178532
RNF180

ring finger protein 180

chr2_+_182464713 1.729 NM_001130445
NM_006751
SSFA2

sperm specific antigen 2

chr8_-_12657339 1.709 NM_152271
LONRF1
LON peptidase N-terminal domain and ring finger 1
chr3_+_180348818 1.535 NM_006218
PIK3CA
phosphoinositide-3-kinase, catalytic, alpha polypeptide
chr8_+_59069522 1.532 NM_147189
FAM110B
family with sequence similarity 110, member B
chr7_+_24579239 1.453 NM_016447
MPP6
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr11_+_86426518 1.448 NM_001168724
NM_022918
TMEM135

transmembrane protein 135

chr21_+_34367747 1.437 MRPS6
mitochondrial ribosomal protein S6
chr2_+_101680594 1.419 NM_004834
NM_145686
NM_145687
MAP4K4


mitogen-activated protein kinase kinase kinase kinase 4


chr17_-_10042579 1.373 NM_201433
GAS7
growth arrest-specific 7
chr9_+_100907189 1.366 TGFBR1
transforming growth factor, beta receptor 1
chr17_+_43081837 1.337 KPNB1
karyopherin (importin) beta 1
chr9_+_100907222 1.334 NM_001130916
NM_004612
TGFBR1

transforming growth factor, beta receptor 1

chr10_+_120779217 1.331 NM_199461
NANOS1
nanos homolog 1 (Drosophila)
chr9_+_100907213 1.316 TGFBR1
transforming growth factor, beta receptor 1
chr17_+_43082302 1.306 KPNB1
karyopherin (importin) beta 1
chr2_+_61146866 1.302 NM_032506
KIAA1841
KIAA1841
chr3_+_73128771 1.276 NM_174907
PPP4R2
protein phosphatase 4, regulatory subunit 2
chr2_+_203901160 1.272 NM_005759
ABI2
abl-interactor 2
chr7_+_93976927 1.272 NM_022900
CASD1
CAS1 domain containing 1
chr9_+_100907292 1.254


chr22_+_30670435 1.234 NM_003405
YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr18_+_18969724 1.226 NM_001100619
CABLES1
Cdk5 and Abl enzyme substrate 1
chr3_+_134775404 1.226 CDV3
CDV3 homolog (mouse)
chr4_+_119419354 1.221 SNHG8
small nucleolar RNA host gene 8 (non-protein coding)
chr2_+_181554048 1.206 UBE2E3
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr14_+_99507848 1.197 EVL
Enah/Vasp-like
chr16_+_24458349 1.168 NM_006910
NM_018703
NM_032626
RBBP6


retinoblastoma binding protein 6


chr1_+_93317374 1.165 NM_001164391
NM_001164392
NM_001164393
NM_007358
MTF2



metal response element binding transcription factor 2



chr9_-_126945536 1.164 NM_001144877
NM_173690
SCAI

suppressor of cancer cell invasion

chr6_-_86445138 1.151 SNHG5
small nucleolar RNA host gene 5 (non-protein coding)
chr10_+_92912676 1.144 PCGF5
polycomb group ring finger 5
chr9_+_130354490 1.137 NM_001130438
NM_001195532
NM_003127
SPTAN1


spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)


chr20_-_32877029 1.137 NM_014071
NCOA6
nuclear receptor coactivator 6
chr15_+_65600520 1.121 NM_001143936
C15orf61
chromosome 15 open reading frame 61
chr22_+_30670543 1.115 YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr1_+_176960896 1.112 NM_152663
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr1_-_94147537 1.089 GCLM
glutamate-cysteine ligase, modifier subunit
chr3_+_112273352 1.073 PVRL3
poliovirus receptor-related 3
chr6_-_163754903 1.068 LOC100526820
hypothetical LOC100526820
chr2_+_191222077 1.066 NM_005966
NAB1
NGFI-A binding protein 1 (EGR1 binding protein 1)
chr7_+_116099648 1.061 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr20_+_36810510 1.059 NM_024855
ACTR5
ARP5 actin-related protein 5 homolog (yeast)
chr21_+_33619067 1.053 NM_000629
IFNAR1
interferon (alpha, beta and omega) receptor 1
chr10_+_105716836 1.046 SLK
STE20-like kinase
chr12_-_98902562 1.042 NM_152788
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr1_-_94147574 1.039 NM_002061
GCLM
glutamate-cysteine ligase, modifier subunit
chr1_+_25629968 1.035 NM_018202
TMEM57
transmembrane protein 57
chr2_+_36436873 1.035 NM_016441
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr14_+_73073570 1.029 NM_001037161
ACOT1
acyl-CoA thioesterase 1
chr2_+_149118791 1.028 EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr20_-_3102169 1.027 ProSAPiP1
ProSAPiP1 protein
chr18_+_9465528 1.022 NM_006788
RALBP1
ralA binding protein 1
chr6_+_157140733 1.019 NM_017519
NM_020732
ARID1B

AT rich interactive domain 1B (SWI1-like)

chr21_+_33619147 1.018 IFNAR1
interferon (alpha, beta and omega) receptor 1
chr11_+_109469296 1.013 NM_033390
ZC3H12C
zinc finger CCCH-type containing 12C
chr16_+_66153810 1.012 NM_001191022
NM_006565
CTCF

CCCTC-binding factor (zinc finger protein)

chr15_+_37660568 1.007 NM_003246
THBS1
thrombospondin 1
chr2_+_181553333 1.006 NM_182678
NM_006357
UBE2E3

ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)

chr20_+_30410447 1.004 ASXL1
additional sex combs like 1 (Drosophila)
chr16_+_83291055 1.002 NM_005153
USP10
ubiquitin specific peptidase 10
chr9_+_91115924 1.000 NM_001827
CKS2
CDC28 protein kinase regulatory subunit 2
chr2_+_85619797 0.998 NM_005911
MAT2A
methionine adenosyltransferase II, alpha
chr2_+_187059277 0.994 ZC3H15
zinc finger CCCH-type containing 15
chr15_-_27650218 0.993 NM_015307
FAM189A1
family with sequence similarity 189, member A1
chr2_+_36436316 0.992 CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr20_-_48980858 0.991 NM_015339
NM_181442
ADNP

activity-dependent neuroprotector homeobox

chr1_+_52380633 0.991 NM_004799
NM_007323
NM_007324
ZFYVE9


zinc finger, FYVE domain containing 9


chr8_+_22354712 0.988 PPP3CC
protein phosphatase 3, catalytic subunit, gamma isozyme
chr17_+_2443652 0.987 NM_000430
PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr12_+_48046946 0.984 NM_023071
SPATS2
spermatogenesis associated, serine-rich 2
chr8_+_22354532 0.983 NM_005605
PPP3CC
protein phosphatase 3, catalytic subunit, gamma isozyme
chr22_+_27993997 0.983 NM_001163285
NM_001163286
NM_001163287
NM_005243
NM_013986
EWSR1




Ewing sarcoma breakpoint region 1




chr3_-_189354510 0.957 LOC339929
hypothetical LOC339929
chr10_+_105716925 0.952 SLK
STE20-like kinase
chr4_+_95592067 0.951 PDLIM5
PDZ and LIM domain 5
chr16_+_83291097 0.936 USP10
ubiquitin specific peptidase 10
chr12_+_105873669 0.928 NM_152261
C12orf23
chromosome 12 open reading frame 23
chr4_+_95592030 0.925 NM_001011513
NM_001011515
NM_001011516
NM_006457
PDLIM5



PDZ and LIM domain 5



chr20_+_5934761 0.921 CRLS1
cardiolipin synthase 1
chr8_+_26204960 0.920 PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr3_+_142143329 0.916 NM_001104647
NM_018155
SLC25A36

solute carrier family 25, member 36

chr4_+_113372287 0.912 NM_001128426
NM_018569
AP1AR

adaptor-related protein complex 1 associated regulatory protein

chr12_+_15366712 0.910 NM_002848
NM_030667
PTPRO

protein tyrosine phosphatase, receptor type, O

chr2_+_28828112 0.899 NM_206876
NM_002709
PPP1CB

protein phosphatase 1, catalytic subunit, beta isozyme

chr20_+_5934560 0.893 NM_019095
CRLS1
cardiolipin synthase 1
chr6_+_157140895 0.893


chr8_+_26204997 0.888 PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr17_+_70964258 0.888 NM_014738
KIAA0195
KIAA0195
chr19_+_37763927 0.887 NM_004708
PDCD5
programmed cell death 5
chr1_+_160797973 0.883 UAP1
UDP-N-acteylglucosamine pyrophosphorylase 1
chr1_+_28936030 0.878 NM_001172828
YTHDF2
YTH domain family, member 2
chr17_+_32924110 0.877 DUSP14
dual specificity phosphatase 14
chr12_+_92295738 0.874 NM_019094
NM_199040
NUDT4

NUDT4P1
nudix (nucleoside diphosphate linked moiety X)-type motif 4

nudix (nucleoside diphosphate linked moiety X)-type motif 4 pseudogene 1
chr13_+_34414390 0.867 NM_015678
NBEA
neurobeachin
chr20_+_56899904 0.867 GNAS
GNAS complex locus
chr2_-_203444468 0.863 NM_138468
ICA1L
islet cell autoantigen 1,69kDa-like
chr2_+_200484251 0.863 C2orf69
chromosome 2 open reading frame 69
chr1_-_92537087 0.855 NM_053274
GLMN
glomulin, FKBP associated protein
chr13_-_109236897 0.850 NM_003749
IRS2
insulin receptor substrate 2
chr4_+_57469122 0.837 REST
RE1-silencing transcription factor
chr21_+_34367678 0.837 NM_032476
NM_006933
MRPS6
SLC5A3
mitochondrial ribosomal protein S6
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr2_+_54536780 0.833 NM_003128
SPTBN1
spectrin, beta, non-erythrocytic 1
chr1_+_92537109 0.833 NM_024813
RPAP2
RNA polymerase II associated protein 2
chr4_+_57468847 0.833 REST
RE1-silencing transcription factor
chr2_+_200484270 0.829 C2orf69
chromosome 2 open reading frame 69
chr5_+_14196287 0.828 NM_007118
TRIO
triple functional domain (PTPRF interacting)
chr15_+_83092854 0.819 ZNF592
zinc finger protein 592
chr8_+_87424074 0.812 NM_007013
WWP1
WW domain containing E3 ubiquitin protein ligase 1
chr3_+_189354167 0.809 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr18_-_72336133 0.807 NM_014643
ZNF516
zinc finger protein 516
chr13_-_105985313 0.806 NM_004093
EFNB2
ephrin-B2
chr10_+_92970302 0.805 NM_032373
PCGF5
polycomb group ring finger 5
chr2_-_200424140 0.801 LOC348751
hypothetical LOC348751
chr13_+_51056648 0.800 WDFY2
WD repeat and FYVE domain containing 2
chr16_+_83291112 0.799 USP10
ubiquitin specific peptidase 10
chr15_+_38013559 0.795 NM_001013703
EIF2AK4
eukaryotic translation initiation factor 2 alpha kinase 4
chr3_+_184898234 0.794 NM_018023
YEATS2
YEATS domain containing 2
chr2_+_170298700 0.793 KLHL23
kelch-like 23 (Drosophila)
chr2_+_9264360 0.792 ASAP2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr7_+_26208532 0.782


chr6_-_13922525 0.780 NM_001031713
CCDC90A
coiled-coil domain containing 90A
chr12_-_37585602 0.778 NM_153634
CPNE8
copine VIII
chr12_+_109203412 0.778 NM_001135765
NM_001681
NM_170665
ATP2A2


ATPase, Ca++ transporting, cardiac muscle, slow twitch 2


chr1_+_213807321 0.770 NM_016121
KCTD3
potassium channel tetramerisation domain containing 3
chr17_+_32924049 0.769 NM_007026
DUSP14
dual specificity phosphatase 14
chr7_-_80386602 0.767 NM_006379
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr2_+_75039273 0.767 NM_019896
POLE4
polymerase (DNA-directed), epsilon 4 (p12 subunit)
chr7_-_80386258 0.761 SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr2_+_149895274 0.758 NM_194317
LYPD6
LY6/PLAUR domain containing 6
chr1_+_36046373 0.757 NM_017629
EIF2C4
eukaryotic translation initiation factor 2C, 4
chr8_+_87595762 0.754 NM_003909
CPNE3
copine III
chr17_+_2443983 0.751 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr9_+_130491340 0.751 SET
SET nuclear oncogene
chr13_+_75021886 0.747 NM_006002
UCHL3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr4_+_140594410 0.746 NM_031296
RAB33B
RAB33B, member RAS oncogene family
chr12_+_95112385 0.746 ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr2_+_28971007 0.741 NM_015131
WDR43
WD repeat domain 43
chr20_+_56899867 0.740 GNAS
GNAS complex locus
chr2_+_46779553 0.737 NM_014011
SOCS5
suppressor of cytokine signaling 5
chr12_+_6907646 0.736 NM_001940
ATN1
atrophin 1
chr16_+_30617962 0.736 NM_006662
SRCAP
Snf2-related CREBBP activator protein
chr4_+_99401543 0.736 NM_001100426
NM_001100427
NM_001100428
NM_001100429
NM_001100430
NM_021159
RAP1GDS1





RAP1, GTP-GDP dissociation stimulator 1





chr13_-_50315832 0.733 NM_198989
DLEU7
deleted in lymphocytic leukemia, 7
chr9_+_90193058 0.729 NM_006717
SPIN1
spindlin 1
chr8_+_87595782 0.719 CPNE3
copine III
chr8_+_28407613 0.715 NM_017412
FZD3
frizzled homolog 3 (Drosophila)
chr11_+_105453501 0.708 NM_015423
AASDHPPT
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr1_-_58815753 0.707 NM_002353
TACSTD2
tumor-associated calcium signal transducer 2
chr12_+_75682016 0.706 ZDHHC17
zinc finger, DHHC-type containing 17
chr12_+_95112131 0.703 NM_005230
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr8_+_22354276 0.701 PPP3CC
protein phosphatase 3, catalytic subunit, gamma isozyme
chr2_+_9264327 0.697 NM_001135191
NM_003887
ASAP2

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

chr3_+_129253977 0.693 SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr4_+_113286001 0.692 NM_152400
C4orf32
chromosome 4 open reading frame 32
chr4_-_110574363 0.689 1/2-SBSRNA4
lncRNA_BC009800
chr6_+_111911226 0.686 LOC643749
hypothetical LOC643749
chr15_-_29950188 0.679 OTUD7A
OTU domain containing 7A
chr13_-_40533072 0.678 ELF1
E74-like factor 1 (ets domain transcription factor)
chr2_+_206732859 0.677 EEF1B2
eukaryotic translation elongation factor 1 beta 2
chr3_+_73128629 0.675 PPP4R2
protein phosphatase 4, regulatory subunit 2
chr12_+_75681973 0.670 NM_015336
ZDHHC17
zinc finger, DHHC-type containing 17
chr13_+_97593711 0.669 FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr11_+_32069183 0.666 RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr17_+_11864841 0.662 NM_003010
MAP2K4
mitogen-activated protein kinase kinase 4
chr3_+_185563872 0.661 NM_006232
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr1_-_62926533 0.659 NM_033407
DOCK7
dedicator of cytokinesis 7
chr16_+_56038837 0.658 NM_020312
COQ9
coenzyme Q9 homolog (S. cerevisiae)
chr16_+_83291107 0.658 USP10
ubiquitin specific peptidase 10
chr14_-_24588916 0.657 NM_014178
STXBP6
syntaxin binding protein 6 (amisyn)
chr17_+_57909979 0.656 NM_001112707
NM_006852
TLK2

tousled-like kinase 2

chr3_+_129253997 0.655 SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr15_+_56850776 0.654 FAM63B
family with sequence similarity 63, member B
chr16_+_15397120 0.653 MPV17L
MPV17 mitochondrial membrane protein-like
chr3_+_134775247 0.650 CDV3
CDV3 homolog (mouse)
chr18_+_58341637 0.647 NM_017742
ZCCHC2
zinc finger, CCHC domain containing 2
chr10_-_104463947 0.646 NM_004311
ARL3
ADP-ribosylation factor-like 3
chr8_+_94998258 0.641 NM_018444
NM_001161780
NM_001161779
NM_001161781
PDP1



pyruvate dehyrogenase phosphatase catalytic subunit 1



chr11_+_8660913 0.635 RPL27A
ribosomal protein L27a
chr16_+_55523248 0.635 NM_001010989
NM_001010990
NM_014685
HERPUD1


homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1


chr1_-_227828416 0.633 NM_001025247
NM_014409
TAF5L

TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa

chr2_+_138975819 0.633 NM_001001664
SPOPL
speckle-type POZ protein-like
chr20_+_6696744 0.631 NM_001200
BMP2
bone morphogenetic protein 2
chr3_+_73128667 0.631 PPP4R2
protein phosphatase 4, regulatory subunit 2
chr10_+_92970487 0.630 PCGF5
polycomb group ring finger 5
chr2_+_97142959 0.629 NM_001164315
ANKRD36
ankyrin repeat domain 36

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.24 1.13e-17 GO:0044237 cellular metabolic process
1.29 7.35e-15 GO:0044260 cellular macromolecule metabolic process
1.21 4.63e-14 GO:0044238 primary metabolic process
1.19 1.24e-13 GO:0008152 metabolic process
1.11 4.19e-11 GO:0009987 cellular process
1.23 5.15e-11 GO:0043170 macromolecule metabolic process
1.42 3.50e-10 GO:0006464 protein modification process
1.35 5.31e-10 GO:0044267 cellular protein metabolic process
1.38 1.11e-08 GO:0043412 macromolecule modification
1.93 3.12e-08 GO:0016568 chromatin modification
1.40 1.05e-07 GO:0006996 organelle organization
1.29 2.95e-07 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.76 3.96e-07 GO:0006325 chromatin organization
1.29 5.13e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.25 7.13e-07 GO:0006807 nitrogen compound metabolic process
1.26 9.82e-07 GO:0034641 cellular nitrogen compound metabolic process
1.26 2.07e-06 GO:0019538 protein metabolic process
1.63 2.75e-06 GO:0051276 chromosome organization
1.28 2.90e-06 GO:0071842 cellular component organization at cellular level
1.23 1.14e-05 GO:0071840 cellular component organization or biogenesis
1.22 3.87e-05 GO:0016043 cellular component organization
1.26 4.34e-05 GO:0009058 biosynthetic process
1.26 8.85e-05 GO:0044249 cellular biosynthetic process
1.80 5.48e-04 GO:0032446 protein modification by small protein conjugation
1.96 1.43e-03 GO:0016569 covalent chromatin modification
1.96 1.91e-03 GO:0016570 histone modification
1.78 2.91e-03 GO:0016567 protein ubiquitination
1.24 3.24e-03 GO:0090304 nucleic acid metabolic process
1.47 4.36e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.66 6.65e-03 GO:0070647 protein modification by small protein conjugation or removal
1.62 1.49e-02 GO:0018193 peptidyl-amino acid modification
1.26 2.29e-02 GO:0009059 macromolecule biosynthetic process
1.34 2.63e-02 GO:0006793 phosphorus metabolic process
1.34 2.63e-02 GO:0006796 phosphate metabolic process
1.32 2.82e-02 GO:0044248 cellular catabolic process
2.35 2.98e-02 GO:0007173 epidermal growth factor receptor signaling pathway
1.26 3.00e-02 GO:0034645 cellular macromolecule biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.18 2.34e-41 GO:0005622 intracellular
1.18 3.46e-40 GO:0044424 intracellular part
1.22 6.65e-27 GO:0005737 cytoplasm
1.17 5.64e-24 GO:0043226 organelle
1.17 7.27e-24 GO:0043229 intracellular organelle
1.19 4.89e-22 GO:0043231 intracellular membrane-bounded organelle
1.19 5.85e-22 GO:0043227 membrane-bounded organelle
1.23 4.62e-16 GO:0044444 cytoplasmic part
1.23 9.36e-14 GO:0005634 nucleus
1.40 1.12e-11 GO:0005829 cytosol
1.21 3.00e-11 GO:0044446 intracellular organelle part
1.20 1.30e-10 GO:0044422 organelle part
1.32 9.23e-08 GO:0044428 nuclear part
1.28 1.87e-06 GO:0031974 membrane-enclosed lumen
1.29 2.22e-06 GO:0070013 intracellular organelle lumen
1.28 3.62e-06 GO:0043233 organelle lumen
1.31 6.50e-06 GO:0031981 nuclear lumen
1.04 1.32e-05 GO:0044464 cell part
1.04 1.39e-05 GO:0005623 cell
1.22 1.64e-04 GO:0043228 non-membrane-bounded organelle
1.22 1.64e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.18 5.65e-04 GO:0032991 macromolecular complex
1.30 1.94e-03 GO:0005739 mitochondrion
1.26 4.09e-03 GO:0012505 endomembrane system
1.73 5.52e-03 GO:0005813 centrosome
1.29 5.58e-03 GO:0005654 nucleoplasm
1.21 1.04e-02 GO:0031090 organelle membrane
1.78 1.30e-02 GO:0031252 cell leading edge
1.84 1.37e-02 GO:0031300 intrinsic to organelle membrane
1.17 1.42e-02 GO:0043234 protein complex
1.55 1.62e-02 GO:0005815 microtubule organizing center
1.45 1.72e-02 GO:0005730 nucleolus
1.85 3.73e-02 GO:0031301 integral to organelle membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.18 9.61e-14 GO:0005515 protein binding
1.10 2.11e-12 GO:0005488 binding
1.21 2.07e-10 GO:0003824 catalytic activity
1.53 2.35e-06 GO:0019899 enzyme binding
1.28 5.46e-06 GO:0000166 nucleotide binding
1.67 6.20e-06 GO:0016874 ligase activity
1.32 7.58e-06 GO:0016740 transferase activity
1.29 5.81e-05 GO:0032553 ribonucleotide binding
1.29 5.81e-05 GO:0032555 purine ribonucleotide binding
1.28 7.61e-05 GO:0017076 purine nucleotide binding
1.29 7.95e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.77 9.22e-05 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.31 2.78e-04 GO:0032559 adenyl ribonucleotide binding
1.30 3.25e-04 GO:0030554 adenyl nucleotide binding
1.30 4.13e-04 GO:0005524 ATP binding
1.75 7.93e-04 GO:0016881 acid-amino acid ligase activity
1.37 2.75e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.18 2.79e-03 GO:0003676 nucleic acid binding
1.74 4.24e-03 GO:0019787 small conjugating protein ligase activity
1.76 5.14e-03 GO:0004842 ubiquitin-protein ligase activity
1.87 7.01e-03 GO:0000287 magnesium ion binding
1.69 1.07e-02 GO:0016791 phosphatase activity
1.14 4.33e-02 GO:0043169 cation binding
1.14 4.55e-02 GO:0046872 metal ion binding
1.14 4.78e-02 GO:0043167 ion binding