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• Activity deltas table
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• Motifs sorted by significance (text)
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Motif ID: HIC1.p2

Z-value: 1.606

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_+_1704661	3.945	NM_001080488	ONECUT3	one cut homeobox 3
chr8_+_145461356	3.519	NM_001008271 NM_001080514	SCXA SCXB	scleraxis homolog A (mouse) scleraxis homolog B (mouse)
chr14_+_105012106	3.344	NM_001312	CRIP2	cysteine-rich protein 2
chr14_+_104226769	3.232	NM_001031714 NM_022489 NM_032714	INF2	inverted formin, FH2 and WH2 domain containing
chr11_+_359723	2.753	NM_178537	B4GALNT4	beta-1,4-N-acetyl-galactosaminyl transferase 4
chr16_+_162845	2.391	NM_000517	HBA1 HBA2	hemoglobin, alpha 1 hemoglobin, alpha 2
chr16_+_2510323	2.357	NM_001145815 NM_015944	AMDHD2	amidohydrolase domain containing 2
chr19_+_540849	2.339	NM_001194	HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr2_+_241586927	2.304	NM_001080437	SNED1	sushi, nidogen and EGF-like domains 1
chr16_+_11669736	2.281	NM_003498	SNN	stannin
chr7_+_154943466	2.251	NM_001427	EN2	engrailed homeobox 2
chr7_-_44331544	2.121	NM_001220 NM_172078 NM_172079 NM_172080 NM_172081 NM_172082 NM_172083 NM_172084	CAMK2B	calcium/calmodulin-dependent protein kinase II beta
chr10_+_112247614	2.058	NM_004419	DUSP5	dual specificity phosphatase 5
chr1_+_2149993	2.057	NM_003036	SKI	v-ski sarcoma viral oncogene homolog (avian)
chr1_+_234372454	2.003	NM_003272	GPR137B	G protein-coupled receptor 137B
chr14_+_104402626	1.992	NM_001112726 NM_015005	KIAA0284	KIAA0284
chr19_+_1236766	1.979	NM_001405	EFNA2	ephrin-A2
chr2_+_238200922	1.965	NM_001137550	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1
chr2_+_232281491	1.896		PTMA	prothymosin, alpha
chr9_+_17568952	1.892	NM_003026	SH3GL2	SH3-domain GRB2-like 2
chr4_+_3737872	1.891		ADRA2C	adrenergic, alpha-2C-, receptor
chr12_+_131705438	1.881	NM_012226 NM_016318 NM_170682 NM_170683 NM_174872 NM_174873	P2RX2	purinergic receptor P2X, ligand-gated ion channel, 2
chr19_+_748452	1.835		PTBP1	polypyrimidine tract binding protein 1
chr14_+_103621768	1.825	NM_001080464	ASPG	asparaginase homolog (S. cerevisiae)
chr13_-_94162249	1.813	NM_007084	SOX21	SRY (sex determining region Y)-box 21
chr4_+_2031036	1.812	NM_178557	NAT8L	N-acetyltransferase 8-like (GCN5-related, putative)
chr9_+_123501186	1.791		DAB2IP	DAB2 interacting protein
chr2_+_120820140	1.781	NM_002193	INHBB	inhibin, beta B
chr16_+_517834	1.754	NM_005632	SOLH	small optic lobes homolog (Drosophila)
chr15_+_39638445	1.720	NM_006293	TYRO3	TYRO3 protein tyrosine kinase
chr19_+_748448	1.706		PTBP1	polypyrimidine tract binding protein 1
chr19_+_748444	1.693		PTBP1	polypyrimidine tract binding protein 1
chr19_+_748390	1.638	NM_002819 NM_031990 NM_031991 NM_175847	PTBP1	polypyrimidine tract binding protein 1
chr14_+_72773957	1.629	NM_173462	NDRG2 PAPLN	NDRG family member 2 papilin, proteoglycan-like sulfated glycoprotein
chr12_+_3056781	1.568	NM_001168320 NM_006675	TSPAN9	tetraspanin 9
chr16_+_1299693	1.563		UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)
chr10_+_134060681	1.555	NM_001098637 NM_138499	PWWP2B	PWWP domain containing 2B
chr3_-_50515857	1.534	NM_001005505 NM_001174051 NM_006030	CACNA2D2	calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr4_-_174687104	1.518		HAND2	heart and neural crest derivatives expressed 2
chr22_+_38183480	1.500		MGAT3	mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr9_+_131974506	1.500	NM_014286	NCS1	neuronal calcium sensor 1
chr17_+_24944605	1.479	NM_152345	ANKRD13B	ankyrin repeat domain 13B
chr11_+_69922236	1.465	NM_001184740 NM_005231 NM_138565	CTTN	cortactin
chr10_-_99521701	1.439	NM_003015	SFRP5	secreted frizzled-related protein 5
chr18_+_75540786	1.420	NM_004715 NM_048368	CTDP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr11_+_627268	1.412	NM_000797	DRD4	dopamine receptor D4
chr18_-_75540727	1.402		FLJ25715	hypothetical protein FLJ25715
chr22_+_38183262	1.400	NM_002409	MGAT3	mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr2_+_241023908	1.391		GPC1	glypican 1
chr4_-_174686918	1.384		HAND2	heart and neural crest derivatives expressed 2
chr16_+_705080	1.379	NM_024042	METRN	meteorin, glial cell differentiation regulator
chr11_-_525532	1.372	NM_001130442 NM_005343 NM_176795	HRAS	v-Ha-ras Harvey rat sarcoma viral oncogene homolog
chr18_+_53253775	1.352	NM_004852	ONECUT2	one cut homeobox 2
chr2_+_232281470	1.347	NM_001099285 NM_002823	PTMA	prothymosin, alpha
chr12_+_119562737	1.342	NM_001033677	CABP1	calcium binding protein 1
chr5_+_153550463	1.340	NM_198321	GALNT10	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr9_-_139060285	1.331		NPDC1	neural proliferation, differentiation and control, 1
chr10_-_103525646	1.329	NM_006119 NM_033163 NM_033164 NM_033165	FGF8	fibroblast growth factor 8 (androgen-induced)
chr16_+_2461500	1.325	NM_006181	NTN3	netrin 3
chr17_-_1560411	1.322	NM_001164407	TLCD2	TLC domain containing 2
chr17_-_4841628	1.317	NM_001167985 NM_001167986 NM_001167987 NM_213726	INCA1	inhibitor of CDK, cyclin A1 interacting protein 1
chr16_+_1299654	1.316		UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)
chr11_-_1549719	1.314	NM_004420	DUSP8	dual specificity phosphatase 8
chr9_-_139060377	1.291		NPDC1	neural proliferation, differentiation and control, 1
chr9_+_138726737	1.281	NM_152421	FAM69B	family with sequence similarity 69, member B
chr16_+_4361775	1.277	NM_138440	VASN	vasorin
chr15_+_94674849	1.267	NM_021005	NR2F2	nuclear receptor subfamily 2, group F, member 2
chr16_+_88517187	1.260	NM_006086	TUBB3	tubulin, beta 3
chr1_+_226261374	1.249	NM_033131	WNT3A	wingless-type MMTV integration site family, member 3A
chr12_+_107047594	1.237	NM_014653	WSCD2	WSC domain containing 2
chrX_+_153339814	1.236	NM_017514	PLXNA3	plexin A3
chr8_+_145705253	1.235	NM_138431	MFSD3	major facilitator superfamily domain containing 3
chr20_+_20296744	1.235	NM_002196	INSM1	insulinoma-associated 1
chr1_-_1274618	1.233		DVL1	dishevelled, dsh homolog 1 (Drosophila)
chr17_+_4841923	1.216	NM_006612	KIF1C	kinesin family member 1C
chr9_+_139091759	1.211	NM_207309	UAP1L1	UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr16_+_1299674	1.210		UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)
chr22_+_28446288	1.210	NM_182527	CABP7	calcium binding protein 7
chr19_+_659766	1.202	NM_001040134 NM_002579	PALM	paralemmin
chr17_+_8865547	1.191	NM_004822	NTN1	netrin 1
chr9_-_95757448	1.188		BARX1	BARX homeobox 1
chr3_+_51403760	1.147	NM_013286	RBM15B	RNA binding motif protein 15B
chr8_+_1937711	1.147		KBTBD11	kelch repeat and BTB (POZ) domain containing 11
chr22_+_48951286	1.143	NM_001160300 NM_052839	PANX2	pannexin 2
chr12_+_109956210	1.140	NM_015267	CUX2	cut-like homeobox 2
chr9_-_100510657	1.140	NM_005458	GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2
chr9_-_95757365	1.137	NM_021570	BARX1	BARX homeobox 1
chr22_-_37180958	1.136	NM_152868	KCNJ4	potassium inwardly-rectifying channel, subfamily J, member 4
chr10_-_134449467	1.129	NM_177400	NKX6-2	NK6 homeobox 2
chr16_-_695719	1.120	NM_153350	FBXL16	F-box and leucine-rich repeat protein 16
chr1_+_36394044	1.114		MAP7D1	MAP7 domain containing 1
chr6_+_1335067	1.106	NM_001452	FOXF2	forkhead box F2
chr18_+_65219114	1.105	NM_152721	DOK6	docking protein 6
chr2_+_241023880	1.101
chr1_+_22762575	1.097	NM_001006943 NM_020526	EPHA8	EPH receptor A8
chr17_+_7152417	1.096	NM_001143762	EIF5A	eukaryotic translation initiation factor 5A
chr16_+_1299637	1.095	NM_003345 NM_194259	UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)
chr15_+_38923914	1.093	NM_001032367	SPINT1	serine peptidase inhibitor, Kunitz type 1
chr6_+_31479340	1.089	NM_000247 NM_001177519	MICA	MHC class I polypeptide-related sequence A
chr20_-_62151216	1.088	NM_018419	SOX18	SRY (sex determining region Y)-box 18
chr1_+_18306823	1.077	NM_032880	IGSF21	immunoglobin superfamily, member 21
chr22_+_31527678	1.074		TIMP3	TIMP metallopeptidase inhibitor 3
chr14_+_63389360	1.068	NM_015180 NM_182914	SYNE2	spectrin repeat containing, nuclear envelope 2
chr14_+_104337923	1.056	NM_001137601	ZBTB42	zinc finger and BTB domain containing 42
chr9_-_139060416	1.052	NM_015392	NPDC1	neural proliferation, differentiation and control, 1
chr22_+_36286350	1.050	NM_152243	CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1
chr14_-_103251497	1.043	NM_001100118 NM_001100119 NM_005432	XRCC3	X-ray repair complementing defective repair in Chinese hamster cells 3
chr2_-_233501069	1.037	NM_001114090	NGEF	neuronal guanine nucleotide exchange factor
chr8_-_144583718	1.032	NM_201589	MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
chr2_+_109112428	1.032	NM_001099289	SH3RF3	SH3 domain containing ring finger 3
chr14_+_89934358	1.031	NM_001166106	CALM1	calmodulin 1 (phosphorylase kinase, delta)
chr1_-_11674264	1.031	NM_001127325	MAD2L2	MAD2 mitotic arrest deficient-like 2 (yeast)
chr22_+_47263919	1.027	NM_001082967	FAM19A5	family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr11_-_69922112	1.023
chr17_+_26060617	1.023
chr22_-_37569679	1.023
chr20_-_61933012	1.008		ZBTB46	zinc finger and BTB domain containing 46
chr11_+_817584	1.007	NM_173584	EFCAB4A	EF-hand calcium binding domain 4A
chr4_+_3738093	1.003	NM_000683	ADRA2C	adrenergic, alpha-2C-, receptor
chr16_+_19032744	1.002	NM_001034841	ITPRIPL2	inositol 1,4,5-triphosphate receptor interacting protein-like 2
chrX_+_151991474	0.997	NM_001170944 NM_032882	LOC100287428 PNMA6A	paraneoplastic antigen-like protein 6A related gene paraneoplastic antigen like 6A
chr19_-_411995	0.987	NM_012435	SHC2	SHC (Src homology 2 domain containing) transforming protein 2
chr18_+_75540831	0.979		CTDP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr15_+_29406335	0.970	NM_015995	KLF13	Kruppel-like factor 13
chr18_+_75724655	0.968	NM_012283	KCNG2	potassium voltage-gated channel, subfamily G, member 2
chr22_+_31527744	0.964		TIMP3	TIMP metallopeptidase inhibitor 3
chr16_+_67697622	0.963	NM_138612	HAS3	hyaluronan synthase 3
chr3_+_51680261	0.959	NM_001129884 NM_015926	TEX264	testis expressed 264
chr7_+_128257698	0.957	NM_001127487 NM_001458	FLNC	filamin C, gamma
chr9_-_138378061	0.955	NM_001080849	DNLZ	DNL-type zinc finger
chrX_+_73557809	0.955	NM_006517	SLC16A2	solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
chr1_-_202921103	0.955	NM_006338 NM_201630	LRRN2	leucine rich repeat neuronal 2
chr7_+_45580704	0.953		ADCY1	adenylate cyclase 1 (brain)
chr17_-_6400470	0.952	NM_001165966 NM_031220	PITPNM3	PITPNM family member 3
chr17_+_11085464	0.947	NM_001173461 NM_001173462 NM_207386	SHISA6	shisa homolog 6 (Xenopus laevis)
chr17_-_29930431	0.944	NM_207454	C17orf102	chromosome 17 open reading frame 102
chr14_+_103251798	0.937	NM_001198953 NM_024071	ZFYVE21	zinc finger, FYVE domain containing 21
chr9_+_136673534	0.930		COL5A1	collagen, type V, alpha 1
chr16_-_73842884	0.926	NM_001170717 NM_014567	BCAR1	breast cancer anti-estrogen resistance 1
chr11_+_2355119	0.922	NM_004356	CD81	CD81 molecule
chr10_+_80672842	0.921		ZMIZ1	zinc finger, MIZ-type containing 1
chr19_+_2173415	0.919		DOT1L	DOT1-like, histone H3 methyltransferase (S. cerevisiae)
chr5_+_14196287	0.915	NM_007118	TRIO	triple functional domain (PTPRF interacting)
chr3_+_53503626	0.913		CACNA1D	calcium channel, voltage-dependent, L type, alpha 1D subunit
chr16_+_270606	0.910	NM_001176	ARHGDIG	Rho GDP dissociation inhibitor (GDI) gamma
chr9_+_139092016	0.908		UAP1L1	UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr9_-_139183675	0.908
chr16_+_88169612	0.906	NM_014427 NM_153636	CPNE7	copine VII
chr15_-_38362078	0.895	NM_001190479	LOC100131244	hypothetical protein LOC100131244
chr20_-_60228665	0.895	NM_007232	HRH3	histamine receptor H3
chr16_+_559970	0.893	NM_004204 NM_148920	PIGQ	phosphatidylinositol glycan anchor biosynthesis, class Q
chr20_+_60810610	0.892	NM_002531	NTSR1	neurotensin receptor 1 (high affinity)
chr10_+_12211586	0.892	NM_001142627 NM_001142628 NM_018144	SEC61A2	Sec61 alpha 2 subunit (S. cerevisiae)
chr17_-_77512346	0.892	NM_178493	NOTUM	notum pectinacetylesterase homolog (Drosophila)
chr20_-_54013418	0.890	NM_080617	CBLN4	cerebellin 4 precursor
chr16_-_371823	0.886	NM_021259	TMEM8A	transmembrane protein 8A
chr7_+_45580606	0.883	NM_021116	ADCY1	adenylate cyclase 1 (brain)
chr11_+_64838882	0.883	NM_006779	CDC42EP2	CDC42 effector protein (Rho GTPase binding) 2
chr14_+_104338423	0.880		ZBTB42	zinc finger and BTB domain containing 42
chr16_+_1324505	0.879	NM_003933	BAIAP3	BAI1-associated protein 3
chr22_-_43784093	0.879	NM_138415	PHF21B	PHD finger protein 21B
chr8_-_41873401	0.877	NM_001142446	ANK1	ankyrin 1, erythrocytic
chr11_+_75056343	0.876
chr6_+_1556543	0.872		FOXC1	forkhead box C1
chr9_-_134986108	0.863	NM_006266	RALGDS	ral guanine nucleotide dissociation stimulator
chr3_+_61522310	0.863		PTPRG	protein tyrosine phosphatase, receptor type, G
chr19_+_10843369	0.860		CARM1	coactivator-associated arginine methyltransferase 1
chr4_+_1764802	0.858	NM_000142 NM_001163213 NM_022965	FGFR3	fibroblast growth factor receptor 3
chr15_+_99237527	0.856	NM_000693	ALDH1A3	aldehyde dehydrogenase 1 family, member A3
chr1_-_6162669	0.855	NM_015557	CHD5	chromodomain helicase DNA binding protein 5
chr1_-_62557559	0.853		KANK4	KN motif and ankyrin repeat domains 4
chr10_+_71908535	0.852	NM_014431	KIAA1274	KIAA1274
chr10_+_133850325	0.851	NM_006426	DPYSL4	dihydropyrimidinase-like 4
chr7_-_5429702	0.850	NM_001080495	TNRC18	trinucleotide repeat containing 18
chr1_+_22909916	0.845	NM_004442 NM_017449	EPHB2	EPH receptor B2
chr14_-_87859284	0.844	NM_138317	KCNK10	potassium channel, subfamily K, member 10
chr5_-_134397740	0.841	NM_002653	PITX1	paired-like homeodomain 1
chr10_+_124211353	0.837		HTRA1	HtrA serine peptidase 1
chr1_-_1274160	0.837	NM_004421	DVL1	dishevelled, dsh homolog 1 (Drosophila)
chr9_-_135847106	0.835	NM_001134398 NM_003371	VAV2	vav 2 guanine nucleotide exchange factor
chr1_+_11674365	0.831	NM_198545	C1orf187	chromosome 1 open reading frame 187
chr19_+_482688	0.831	NM_004359	CDC34	cell division cycle 34 homolog (S. cerevisiae)
chr15_-_91433165	0.826	NM_020211	RGMA	RGM domain family, member A
chr9_+_86473273	0.824	NM_001018064 NM_006180	NTRK2	neurotrophic tyrosine kinase, receptor, type 2
chr19_+_1358664	0.819		DAZAP1	DAZ associated protein 1
chr10_+_128583984	0.819	NM_001380	DOCK1	dedicator of cytokinesis 1
chr14_+_95575319	0.818		C14orf132	chromosome 14 open reading frame 132
chr16_+_166678	0.814	NM_000558	HBA1 HBA2	hemoglobin, alpha 1 hemoglobin, alpha 2
chr10_+_23521464	0.813	NM_178161	PTF1A	pancreas specific transcription factor, 1a
chr19_-_6230927	0.813	NM_005934	MLLT1	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr5_+_76542461	0.806	NM_001029851 NM_001029852 NM_001029853 NM_001029854 NM_003719	PDE8B	phosphodiesterase 8B
chr22_-_49041786	0.804		MAPK12	mitogen-activated protein kinase 12
chr9_-_111122826	0.804	NM_018424 NM_019114	EPB41L4B	erythrocyte membrane protein band 4.1 like 4B
chr16_+_550394	0.804	NM_145270	C16orf11	chromosome 16 open reading frame 11
chr14_+_101097440	0.802	NM_001362	DIO3	deiodinase, iodothyronine, type III
chrX_+_21868635	0.802	NM_004595	SMS	spermine synthase
chr9_-_139184247	0.802	NM_001013653	LRRC26	leucine rich repeat containing 26
chr14_-_104706159	0.801	NM_002226 NM_145159	JAG2	jagged 2
chr21_-_45786709	0.799	NM_194255	SLC19A1	solute carrier family 19 (folate transporter), member 1
chr9_+_94898346	0.798		C9orf89	chromosome 9 open reading frame 89

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.49	5.87e-22	GO:0007399	nervous system development
1.40	1.38e-20	GO:0030154	cell differentiation
1.39	5.30e-20	GO:0048869	cellular developmental process
1.61	9.93e-20	GO:0022008	neurogenesis
1.61	3.26e-18	GO:0048699	generation of neurons
1.16	1.45e-17	GO:0050794	regulation of cellular process
1.57	3.22e-17	GO:0048468	cell development
1.41	4.02e-17	GO:0023051	regulation of signaling
1.43	1.47e-16	GO:0009653	anatomical structure morphogenesis
1.14	1.53e-16	GO:0065007	biological regulation
1.64	6.87e-16	GO:0030182	neuron differentiation
1.75	1.55e-15	GO:0000904	cell morphogenesis involved in differentiation
1.78	7.21e-15	GO:0048812	neuron projection morphogenesis
1.78	1.20e-14	GO:0048667	cell morphogenesis involved in neuron differentiation
1.80	1.33e-14	GO:0007409	axonogenesis
1.14	1.49e-14	GO:0050789	regulation of biological process
1.25	1.80e-14	GO:0007275	multicellular organismal development
1.28	3.49e-14	GO:0048731	system development
1.66	1.41e-13	GO:0048666	neuron development
1.71	1.52e-13	GO:0031175	neuron projection development
1.70	2.14e-13	GO:0032990	cell part morphogenesis
1.22	2.83e-13	GO:0032502	developmental process
1.69	3.65e-13	GO:0048858	cell projection morphogenesis
1.40	5.57e-13	GO:0009966	regulation of signal transduction
1.63	6.48e-13	GO:0000902	cell morphogenesis
1.60	1.24e-12	GO:0032989	cellular component morphogenesis
1.24	1.99e-12	GO:0048856	anatomical structure development
1.29	5.42e-12	GO:0048519	negative regulation of biological process
1.08	7.52e-12	GO:0009987	cellular process
1.44	1.01e-11	GO:0010646	regulation of cell communication
1.81	1.63e-11	GO:0007411	axon guidance
1.57	3.36e-11	GO:0030030	cell projection organization
1.29	4.32e-11	GO:0048523	negative regulation of cellular process
1.44	2.46e-10	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.57	1.23e-08	GO:0007417	central nervous system development
1.23	1.64e-08	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.73	5.01e-08	GO:0048729	tissue morphogenesis
1.19	5.10e-08	GO:0031323	regulation of cellular metabolic process
1.22	1.36e-07	GO:0051171	regulation of nitrogen compound metabolic process
1.54	1.45e-07	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.22	1.58e-07	GO:0010468	regulation of gene expression
1.18	1.64e-07	GO:0080090	regulation of primary metabolic process
1.49	2.40e-07	GO:0009887	organ morphogenesis
1.81	2.41e-07	GO:0002009	morphogenesis of an epithelium
1.27	2.52e-07	GO:0048583	regulation of response to stimulus
1.24	4.22e-07	GO:0051252	regulation of RNA metabolic process
1.46	5.37e-07	GO:0051254	positive regulation of RNA metabolic process
1.22	5.48e-07	GO:0048522	positive regulation of cellular process
1.47	6.21e-07	GO:0045893	positive regulation of transcription, DNA-dependent
1.62	6.29e-07	GO:0048598	embryonic morphogenesis
1.58	6.96e-07	GO:0009968	negative regulation of signal transduction
1.46	8.16e-07	GO:0007167	enzyme linked receptor protein signaling pathway
1.45	8.76e-07	GO:0010628	positive regulation of gene expression
1.56	9.19e-07	GO:0023057	negative regulation of signaling
1.97	9.39e-07	GO:0060562	epithelial tube morphogenesis
1.55	1.14e-06	GO:0010648	negative regulation of cell communication
1.86	1.32e-06	GO:0035239	tube morphogenesis
1.39	1.46e-06	GO:0009888	tissue development
1.16	3.32e-06	GO:0019222	regulation of metabolic process
1.16	4.23e-06	GO:0023052	signaling
1.68	5.01e-06	GO:0035295	tube development
1.20	7.08e-06	GO:0031326	regulation of cellular biosynthetic process
1.20	8.15e-06	GO:0009889	regulation of biosynthetic process
1.42	8.81e-06	GO:0009790	embryo development
1.24	9.80e-06	GO:0048513	organ development
1.20	1.01e-05	GO:0071842	cellular component organization at cellular level
1.22	1.03e-05	GO:0006355	regulation of transcription, DNA-dependent
1.44	1.17e-05	GO:0010629	negative regulation of gene expression
1.41	1.27e-05	GO:0009890	negative regulation of biosynthetic process
1.17	1.35e-05	GO:0060255	regulation of macromolecule metabolic process
1.19	1.51e-05	GO:0048518	positive regulation of biological process
1.46	2.17e-05	GO:0045892	negative regulation of transcription, DNA-dependent
1.49	2.21e-05	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.43	2.22e-05	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.46	2.31e-05	GO:0051253	negative regulation of RNA metabolic process
2.20	2.80e-05	GO:0021915	neural tube development
1.20	3.19e-05	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.56	3.66e-05	GO:0007420	brain development
1.40	3.67e-05	GO:0031327	negative regulation of cellular biosynthetic process
1.42	4.13e-05	GO:0051172	negative regulation of nitrogen compound metabolic process
1.41	4.50e-05	GO:0010558	negative regulation of macromolecule biosynthetic process
1.16	5.92e-05	GO:0016043	cellular component organization
1.46	6.54e-05	GO:0048585	negative regulation of response to stimulus
1.75	6.64e-05	GO:0032582	negative regulation of gene-specific transcription
2.71	6.74e-05	GO:0001843	neural tube closure
1.58	7.47e-05	GO:0060284	regulation of cell development
1.56	8.21e-05	GO:0007389	pattern specification process
1.34	9.85e-05	GO:0006351	transcription, DNA-dependent
1.36	9.90e-05	GO:0051173	positive regulation of nitrogen compound metabolic process
1.51	1.04e-04	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.19	1.04e-04	GO:0010556	regulation of macromolecule biosynthetic process
1.49	1.09e-04	GO:0032583	regulation of gene-specific transcription
1.41	1.33e-04	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.36	1.39e-04	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.52	1.53e-04	GO:0060429	epithelium development
2.64	1.57e-04	GO:0060606	tube closure
1.36	1.68e-04	GO:0010557	positive regulation of macromolecule biosynthetic process
1.16	2.08e-04	GO:0007165	signal transduction
1.27	2.14e-04	GO:0051239	regulation of multicellular organismal process
1.46	2.21e-04	GO:0048646	anatomical structure formation involved in morphogenesis
1.60	2.28e-04	GO:0051960	regulation of nervous system development
1.44	2.54e-04	GO:0006935	chemotaxis
1.44	2.54e-04	GO:0042330	taxis
1.52	2.57e-04	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
2.13	2.98e-04	GO:0021953	central nervous system neuron differentiation
2.57	3.46e-04	GO:0014020	primary neural tube formation
1.51	3.62e-04	GO:0009792	embryo development ending in birth or egg hatching
1.55	3.70e-04	GO:0001501	skeletal system development
1.32	4.35e-04	GO:0050793	regulation of developmental process
1.50	4.55e-04	GO:0051056	regulation of small GTPase mediated signal transduction
1.17	5.00e-04	GO:0071841	cellular component organization or biogenesis at cellular level
1.37	5.07e-04	GO:0045595	regulation of cell differentiation
1.65	5.30e-04	GO:0048011	nerve growth factor receptor signaling pathway
1.50	5.72e-04	GO:0043009	chordate embryonic development
1.94	5.97e-04	GO:0048736	appendage development
1.94	5.97e-04	GO:0060173	limb development
1.77	6.42e-04	GO:0010553	negative regulation of gene-specific transcription from RNA polymerase II promoter
2.05	7.03e-04	GO:0060828	regulation of canonical Wnt receptor signaling pathway
2.39	7.42e-04	GO:0001841	neural tube formation
1.32	7.76e-04	GO:0040011	locomotion
1.21	7.96e-04	GO:0007166	cell surface receptor linked signaling pathway
2.11	8.46e-04	GO:0016331	morphogenesis of embryonic epithelium
2.25	9.05e-04	GO:0001838	embryonic epithelial tube formation
1.32	9.71e-04	GO:0031328	positive regulation of cellular biosynthetic process
1.13	1.08e-03	GO:0051716	cellular response to stimulus
1.60	1.38e-03	GO:0050767	regulation of neurogenesis
1.29	1.55e-03	GO:0042127	regulation of cell proliferation
2.21	1.57e-03	GO:0072175	epithelial tube formation
1.19	1.70e-03	GO:0065008	regulation of biological quality
1.18	1.74e-03	GO:0042221	response to chemical stimulus
1.98	1.94e-03	GO:0030326	embryonic limb morphogenesis
1.98	1.94e-03	GO:0035113	embryonic appendage morphogenesis
1.31	2.07e-03	GO:0009891	positive regulation of biosynthetic process
1.30	2.63e-03	GO:0010605	negative regulation of macromolecule metabolic process
1.80	2.79e-03	GO:0030111	regulation of Wnt receptor signaling pathway
1.90	3.01e-03	GO:0035107	appendage morphogenesis
1.90	3.01e-03	GO:0035108	limb morphogenesis
1.33	3.12e-03	GO:2000026	regulation of multicellular organismal development
1.14	3.55e-03	GO:0071840	cellular component organization or biogenesis
1.28	4.53e-03	GO:0009892	negative regulation of metabolic process
1.70	6.58e-03	GO:0006813	potassium ion transport
1.23	7.15e-03	GO:0035556	intracellular signal transduction
2.11	7.33e-03	GO:0035148	tube formation
1.42	8.18e-03	GO:0008285	negative regulation of cell proliferation
1.86	8.28e-03	GO:0010720	positive regulation of cell development
1.27	8.91e-03	GO:0032774	RNA biosynthetic process
1.13	9.15e-03	GO:0051179	localization
1.56	9.19e-03	GO:0040007	growth
1.23	1.22e-02	GO:0009893	positive regulation of metabolic process
1.75	1.25e-02	GO:0048705	skeletal system morphogenesis
1.24	1.28e-02	GO:0031325	positive regulation of cellular metabolic process
1.26	1.75e-02	GO:0009605	response to external stimulus
1.27	1.84e-02	GO:0031324	negative regulation of cellular metabolic process
1.29	2.09e-02	GO:0051128	regulation of cellular component organization
2.01	2.18e-02	GO:0001657	ureteric bud development
1.98	2.51e-02	GO:0010721	negative regulation of cell development
1.24	2.63e-02	GO:0010604	positive regulation of macromolecule metabolic process
1.47	2.71e-02	GO:0022603	regulation of anatomical structure morphogenesis
2.09	2.75e-02	GO:0050768	negative regulation of neurogenesis
1.53	2.89e-02	GO:0003002	regionalization
1.73	2.91e-02	GO:0010769	regulation of cell morphogenesis involved in differentiation
1.36	3.45e-02	GO:0019226	transmission of nerve impulse
1.36	3.45e-02	GO:0035637	multicellular organismal signaling
1.72	3.91e-02	GO:0022604	regulation of cell morphogenesis
1.61	4.13e-02	GO:0030900	forebrain development
1.13	4.39e-02	GO:0051234	establishment of localization
1.56	4.63e-02	GO:0045664	regulation of neuron differentiation
1.90	4.68e-02	GO:0030178	negative regulation of Wnt receptor signaling pathway
1.47	4.88e-02	GO:0051270	regulation of cellular component movement

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.08	1.45e-13	GO:0044424	intracellular part
1.08	7.29e-13	GO:0005622	intracellular
1.58	8.79e-08	GO:0045202	synapse
1.09	1.47e-07	GO:0005737	cytoplasm
1.07	8.80e-07	GO:0043226	organelle
1.08	1.34e-06	GO:0043227	membrane-bounded organelle
1.07	1.65e-06	GO:0043229	intracellular organelle
1.08	1.92e-06	GO:0043231	intracellular membrane-bounded organelle
1.03	2.09e-06	GO:0044464	cell part
1.03	2.25e-06	GO:0005623	cell
1.11	1.79e-05	GO:0005634	nucleus
1.55	6.66e-05	GO:0044456	synapse part
1.35	9.00e-04	GO:0030054	cell junction
1.43	9.79e-04	GO:0043005	neuron projection
1.18	1.06e-03	GO:0005829	cytosol
1.09	1.76e-03	GO:0044444	cytoplasmic part
1.50	4.92e-03	GO:0005667	transcription factor complex
1.58	8.60e-03	GO:0044297	cell body
1.58	1.12e-02	GO:0043025	neuronal cell body
1.20	1.20e-02	GO:0005654	nucleoplasm
1.17	1.51e-02	GO:0031981	nuclear lumen
1.14	4.84e-02	GO:0044459	plasma membrane part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.48	1.12e-14	GO:0030528	transcription regulator activity
1.43	4.95e-11	GO:0001071	nucleic acid binding transcription factor activity
1.43	4.95e-11	GO:0003700	sequence-specific DNA binding transcription factor activity
1.46	2.03e-08	GO:0043565	sequence-specific DNA binding
1.66	6.03e-08	GO:0016563	transcription activator activity
1.06	1.80e-07	GO:0005488	binding
1.81	3.90e-07	GO:0010843	promoter binding
1.51	7.81e-07	GO:0030695	GTPase regulator activity
1.78	8.28e-07	GO:0000975	regulatory region DNA binding
1.78	8.28e-07	GO:0001067	regulatory region nucleic acid binding
1.78	8.28e-07	GO:0044212	transcription regulatory region DNA binding
1.10	1.73e-06	GO:0005515	protein binding
1.48	4.36e-06	GO:0060589	nucleoside-triphosphatase regulator activity
1.71	5.67e-05	GO:0005244	voltage-gated ion channel activity
1.71	5.67e-05	GO:0022832	voltage-gated channel activity
1.76	5.01e-04	GO:0022843	voltage-gated cation channel activity
1.17	8.06e-04	GO:0003677	DNA binding
1.93	8.53e-04	GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity
1.41	1.08e-03	GO:0019904	protein domain specific binding
1.54	1.60e-03	GO:0005096	GTPase activator activity
1.95	1.79e-03	GO:0003705	sequence-specific enhancer binding RNA polymerase II transcription factor activity
1.47	3.28e-03	GO:0016564	transcription repressor activity
1.85	3.79e-03	GO:0016566	specific transcriptional repressor activity
1.87	6.19e-03	GO:0003704	specific RNA polymerase II transcription factor activity
1.71	1.04e-02	GO:0005267	potassium channel activity
1.49	1.12e-02	GO:0003702	RNA polymerase II transcription factor activity
1.44	1.23e-02	GO:0022836	gated channel activity
1.79	1.39e-02	GO:0005249	voltage-gated potassium channel activity
1.44	2.21e-02	GO:0005083	small GTPase regulator activity
1.45	2.92e-02	GO:0005261	cation channel activity
1.42	4.32e-02	GO:0008134	transcription factor binding
1.23	4.36e-02	GO:0022857	transmembrane transporter activity