Motif ID: HIF1A.p2

Z-value: 0.819


Transcription factors associated with HIF1A.p2:

Gene SymbolEntrez IDGene Name
HIF1A 3091 hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)



Activity profile for motif HIF1A.p2.

activity profile for motif HIF1A.p2


Sorted Z-values histogram for motif HIF1A.p2

Sorted Z-values for motif HIF1A.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HIF1A.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_97016027 1.633 NM_001122646
FAM178B
family with sequence similarity 178, member B
chr5_+_78568094 1.151


chr11_+_18372689 1.104 LDHA
lactate dehydrogenase A
chr17_+_77780177 1.094 NM_004207
SLC16A3
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr7_+_156624424 1.086 UBE3C
ubiquitin protein ligase E3C
chr20_+_30410447 1.075 ASXL1
additional sex combs like 1 (Drosophila)
chr13_-_43259032 1.036 NM_017993
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr7_+_156624392 1.034 NM_014671
UBE3C
ubiquitin protein ligase E3C
chr11_+_18372687 1.027 LDHA
lactate dehydrogenase A
chr11_+_18372493 1.024 NM_001135239
NM_001165415
NM_001165416
NM_005566
LDHA



lactate dehydrogenase A



chr11_+_18372708 0.997 LDHA
lactate dehydrogenase A
chr2_-_74915722 0.924


chr7_+_156624370 0.876 UBE3C
ubiquitin protein ligase E3C
chr20_+_41519947 0.847 SRSF6
serine/arginine-rich splicing factor 6
chr20_+_41519882 0.818 NM_006275
SRSF6
serine/arginine-rich splicing factor 6
chr10_+_104394185 0.809 NM_030912
TRIM8
tripartite motif containing 8
chr1_+_109963982 0.804 AMPD2
adenosine monophosphate deaminase 2
chr8_+_49083522 0.783 NM_003350
UBE2V2
ubiquitin-conjugating enzyme E2 variant 2
chr17_+_52517529 0.758 NM_003488
AKAP1
A kinase (PRKA) anchor protein 1
chr12_+_68923043 0.714 NM_014515
CNOT2
CCR4-NOT transcription complex, subunit 2
chr1_+_109963950 0.695 NM_139156
AMPD2
adenosine monophosphate deaminase 2
chr8_+_17398940 0.651 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr20_+_32414715 0.650 NM_031483
ITCH
itchy E3 ubiquitin protein ligase homolog (mouse)
chr16_+_14634324 0.630 BFAR
bifunctional apoptosis regulator
chr2_+_138975819 0.619 NM_001001664
SPOPL
speckle-type POZ protein-like
chr18_+_31963851 0.610 ELP2
elongation protein 2 homolog (S. cerevisiae)
chr3_+_184898234 0.600 NM_018023
YEATS2
YEATS domain containing 2
chr20_+_30409649 0.598 NM_001164603
NM_015338
ASXL1

additional sex combs like 1 (Drosophila)

chr12_+_105873803 0.586 C12orf23
chromosome 12 open reading frame 23
chr18_+_31963879 0.575 NM_018255
ELP2
elongation protein 2 homolog (S. cerevisiae)
chr2_+_32142083 0.574 NM_014946
NM_199436
SPAST

spastin

chr6_+_87921980 0.548 NM_015021
ZNF292
zinc finger protein 292
chr17_+_75366524 0.544 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr6_+_43846735 0.525 VEGFA
vascular endothelial growth factor A
chr5_+_78567604 0.521 NM_152405
JMY
junction mediating and regulatory protein, p53 cofactor
chr17_+_42355482 0.515 NM_001012511
NM_004287
NM_054022
GOSR2


golgi SNAP receptor complex member 2


chr2_+_138975946 0.514


chr2_+_111594921 0.512 NM_006538
NM_138621
NM_207002
BCL2L11


BCL2-like 11 (apoptosis facilitator)


chr2_+_173129119 0.512 PDK1
pyruvate dehydrogenase kinase, isozyme 1
chr3_-_50311666 0.511 NM_012191
NM_003549
NAT6
HYAL3
N-acetyltransferase 6 (GCN5-related)
hyaluronoglucosaminidase 3
chr16_-_23476138 0.508 NM_001083614
EARS2
glutamyl-tRNA synthetase 2, mitochondrial (putative)
chr2_-_241903787 0.504 HDLBP
high density lipoprotein binding protein
chr2_+_173129040 0.495 PDK1
pyruvate dehydrogenase kinase, isozyme 1
chr11_+_566482 0.494 NM_020901
PHRF1
PHD and ring finger domains 1
chr2_-_254037 0.485 NM_001159597
NM_015677
SH3YL1

SH3 domain containing, Ysc84-like 1 (S. cerevisiae)

chr2_-_253982 0.475 SH3YL1
SH3 domain containing, Ysc84-like 1 (S. cerevisiae)
chrX_+_152252738 0.475 NM_001080485
ZNF275
zinc finger protein 275
chr2_-_198073242 0.461 NM_199440
HSPD1
heat shock 60kDa protein 1 (chaperonin)
chr13_-_97627491 0.456 NM_178861
RNF113B
ring finger protein 113B
chr2_+_28828112 0.454 NM_206876
NM_002709
PPP1CB

protein phosphatase 1, catalytic subunit, beta isozyme

chr7_+_17304707 0.452 NM_001621
AHR
aryl hydrocarbon receptor
chr3_-_50311262 0.452 NAT6
HYAL3
N-acetyltransferase 6 (GCN5-related)
hyaluronoglucosaminidase 3
chr2_-_198072767 0.451 HSPD1
heat shock 60kDa protein 1 (chaperonin)
chr2_-_170389669 0.447 METTL5
methyltransferase like 5
chr20_+_3399615 0.447 NM_139321
NM_139322
ATRN

attractin

chr2_+_122229590 0.446 NM_004622
TSN
translin
chr1_+_28717349 0.445 RCC1
regulator of chromosome condensation 1
chr3_-_57088332 0.442 NM_001128615
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr7_+_149696263 0.442 REPIN1
replication initiator 1
chr2_-_198072805 0.439 HSPD1
heat shock 60kDa protein 1 (chaperonin)
chr14_+_30098079 0.438 NM_017769
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr19_+_1022208 0.436 HMHA1
histocompatibility (minor) HA-1
chr22_+_48740143 0.430 NM_001001852
PIM3
pim-3 oncogene
chr2_+_198072965 0.429 NM_002157
HSPE1
heat shock 10kDa protein 1 (chaperonin 10)
chr2_-_170389598 0.427 NM_014168
METTL5
methyltransferase like 5
chr7_+_97748959 0.424 BRI3
brain protein I3
chr17_+_42355492 0.423 GOSR2
golgi SNAP receptor complex member 2
chr10_-_60606195 0.423


chr20_+_48241334 0.421 CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr2_+_241903395 0.416 NM_001008491
NM_006155
SEPT2

septin 2

chr11_+_18372682 0.412 LDHA
lactate dehydrogenase A
chr16_+_31098931 0.411 NM_001170634
NM_001170937
NM_004960
FUS


fused in sarcoma


chr12_+_6514228 0.408 GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr12_+_105873669 0.406 NM_152261
C12orf23
chromosome 12 open reading frame 23
chr20_-_17897067 0.395 NM_014426
SNX5
sorting nexin 5
chrX_+_77246321 0.390 NM_000291
PGK1
phosphoglycerate kinase 1
chrX_+_77246368 0.383 PGK1
phosphoglycerate kinase 1
chr2_-_198072868 0.383 NM_002156
HSPD1
heat shock 60kDa protein 1 (chaperonin)
chr20_+_3399727 0.382 ATRN
attractin
chr2_+_187059277 0.380 ZC3H15
zinc finger CCCH-type containing 15
chr7_+_97748914 0.380 NM_001159491
NM_015379
BRI3

brain protein I3

chr19_+_1358664 0.380 DAZAP1
DAZ associated protein 1
chr16_+_14634168 0.374 NM_016561
BFAR
bifunctional apoptosis regulator
chr12_+_6514160 0.372 GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr3_+_23962518 0.372 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr19_+_1358531 0.372 NM_018959
NM_170711
DAZAP1

DAZ associated protein 1

chr2_+_220007943 0.371 NM_005876
SPEG
SPEG complex locus
chr21_+_39099717 0.371 NM_005239
ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr6_-_153346283 0.370 NM_001142522
FBXO5
F-box protein 5
chr22_+_39818553 0.368 NM_001429
EP300
E1A binding protein p300
chr21_+_39099624 0.367 ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr17_+_32924110 0.365 DUSP14
dual specificity phosphatase 14
chr1_+_191357680 0.364 NM_024529
CDC73
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr12_+_6893751 0.364 NM_001975
ENO2
enolase 2 (gamma, neuronal)
chrX_+_77246409 0.361 PGK1
phosphoglycerate kinase 1
chr2_-_138975682 0.361


chr5_+_126881207 0.361 NM_130809
PRRC1
proline-rich coiled-coil 1
chr10_+_73703682 0.360 NM_019058
DDIT4
DNA-damage-inducible transcript 4
chr6_-_35216981 0.359 NM_001093728
NM_018679
TCP11

t-complex 11 homolog (mouse)

chr11_+_65049552 0.356 SCYL1
SCY1-like 1 (S. cerevisiae)
chr1_+_65386359 0.355 NM_013410
AK4
adenylate kinase 4
chr2_+_46779827 0.352 NM_144949
SOCS5
suppressor of cytokine signaling 5
chr16_+_31098971 0.351 FUS
fused in sarcoma
chr11_-_565848 0.350 LOC143666
hypothetical LOC143666
chr6_+_7671267 0.350 BMP6
bone morphogenetic protein 6
chr9_+_131428225 0.349 NM_014064
METTL11A
methyltransferase like 11A
chr18_+_58341637 0.347 NM_017742
ZCCHC2
zinc finger, CCHC domain containing 2
chr9_+_131428272 0.346 METTL11A
methyltransferase like 11A
chr3_-_52694554 0.344 NM_018313
PBRM1
polybromo 1
chr9_+_137532294 0.344 NM_016034
MRPS2
mitochondrial ribosomal protein S2
chr16_+_31098959 0.343 FUS
fused in sarcoma
chr2_+_198073257 0.343 HSPE1
heat shock 10kDa protein 1 (chaperonin 10)
chr2_+_187059237 0.343 ZC3H15
zinc finger CCCH-type containing 15
chr20_+_48781457 0.342 NM_032521
PARD6B
par-6 partitioning defective 6 homolog beta (C. elegans)
chr1_+_65386559 0.342 AK4
adenylate kinase 4
chr2_-_108517028 0.341 FLJ38668
hypothetical LOC644903
chr6_+_16237300 0.339 MYLIP
myosin regulatory light chain interacting protein
chr6_+_46763570 0.336 NM_001010870
NM_001168359
TDRD6

tudor domain containing 6

chr22_+_39072448 0.336 NM_000026
NM_001123378
ADSL

adenylosuccinate lyase

chr4_+_56997205 0.336 PAICS
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr16_+_3447957 0.332 NM_001083600
NM_024845
NAT15

N-acetyltransferase 15 (GCN5-related, putative)

chr2_+_62276764 0.329 NM_006577
B3GNT2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
chr13_+_114098045 0.328 NM_001164144
NM_001164145
NM_032436
ZNF828


zinc finger protein 828


chr2_+_177785667 0.323 NM_194247
HNRNPA3P1
HNRNPA3
heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
heterogeneous nuclear ribonucleoprotein A3
chr12_+_129922589 0.322 RAN
RAN, member RAS oncogene family
chr20_+_34635362 0.320 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr21_+_44544381 0.319 PFKL
phosphofructokinase, liver
chr6_+_30647148 0.319 NM_001025091
NM_001090
ABCF1

ATP-binding cassette, sub-family F (GCN20), member 1

chr9_-_139316523 0.318 NM_001004354
NRARP
NOTCH-regulated ankyrin repeat protein
chr2_-_241903657 0.315 HDLBP
high density lipoprotein binding protein
chr19_+_1358750 0.312 DAZAP1
DAZ associated protein 1
chr17_-_71815176 0.308 NM_032134
QRICH2
glutamine rich 2
chr7_+_127883117 0.307 NM_001098786
NM_013332
C7orf68

chromosome 7 open reading frame 68

chr2_+_187059115 0.306 NM_018471
ZC3H15
zinc finger CCCH-type containing 15
chr3_-_40473723 0.306


chr20_+_56989690 0.302 NM_198976
TH1L
TH1-like (Drosophila)
chr7_+_138695537 0.300 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr3_+_157874898 0.300 NM_015508
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr7_+_6735911 0.299


chr17_-_72045218 0.299 NM_134268
CYGB
cytoglobin
chr2_+_131579355 0.298 PLEKHB2
pleckstrin homology domain containing, family B (evectins) member 2
chr2_-_219791638 0.298 ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr6_+_2710675 0.297 WRNIP1
Werner helicase interacting protein 1
chr1_+_191357788 0.296 CDC73
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr8_+_26296439 0.294 NM_004331
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr20_-_60151835 0.293 NM_002792
PSMA7
proteasome (prosome, macropain) subunit, alpha type, 7
chr2_+_131579334 0.292 PLEKHB2
pleckstrin homology domain containing, family B (evectins) member 2
chr6_+_36206239 0.292 NM_002754
MAPK13
mitogen-activated protein kinase 13
chr20_-_60151753 0.291 PSMA7
proteasome (prosome, macropain) subunit, alpha type, 7
chr2_+_236067424 0.291 NM_001037131
NM_014914
AGAP1

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

chr21_+_44544349 0.289 NM_002626
PFKL
phosphofructokinase, liver
chr22_+_34107051 0.287 NM_002133
HMOX1
heme oxygenase (decycling) 1
chrX_+_152608159 0.287 NM_001142806
SLC6A8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr6_+_160068531 0.287 WTAP
Wilms tumor 1 associated protein
chr10_+_93548119 0.285 NM_025235
TNKS2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr16_+_23476334 0.285 NM_019116
UBFD1
ubiquitin family domain containing 1
chr2_+_203901160 0.285 NM_005759
ABI2
abl-interactor 2
chr4_+_186554958 0.283 ANKRD37
ankyrin repeat domain 37
chr10_-_43223226 0.283 NM_001098206
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr19_+_2736464 0.283 NM_003249
THOP1
thimet oligopeptidase 1
chr6_+_12120709 0.282 NM_002114
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr1_+_65385799 0.282 NM_203464
NM_001005353
AK4

adenylate kinase 4

chr2_-_219791902 0.281 NM_005689
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr1_+_191357843 0.278 CDC73
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr3_+_52694975 0.277 NM_014366
NM_206825
NM_206826
GNL3


guanine nucleotide binding protein-like 3 (nucleolar)


chr3_+_124268545 0.277 NM_006810
PDIA5
protein disulfide isomerase family A, member 5
chr22_+_48633484 0.277 NM_014838
ZBED4
zinc finger, BED-type containing 4
chr17_+_44340719 0.276 NM_023079
UBE2Z
ubiquitin-conjugating enzyme E2Z
chr4_+_56997155 0.276 PAICS
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr14_+_96038521 0.276 PAPOLA
poly(A) polymerase alpha
chr14_+_96038479 0.276 PAPOLA
poly(A) polymerase alpha
chr16_+_55523248 0.275 NM_001010989
NM_001010990
NM_014685
HERPUD1


homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1


chr16_+_387176 0.274 NM_005009
NME4
non-metastatic cells 4, protein expressed in
chr20_+_17897529 0.274 NM_052865
C20orf72
chromosome 20 open reading frame 72
chr3_+_5204403 0.274 EDEM1
ER degradation enhancer, mannosidase alpha-like 1
chr20_+_56989717 0.271 TH1L
TH1-like (Drosophila)
chr13_+_97426713 0.270 IPO5
importin 5
chr17_+_44340828 0.270 UBE2Z
ubiquitin-conjugating enzyme E2Z
chr17_+_50697319 0.270 NM_002126
HLF
hepatic leukemia factor
chrX_+_77246430 0.270 PGK1
phosphoglycerate kinase 1
chr16_+_30113821 0.269 NM_001017389
NM_003166
SULT1A4
SULT1A3
SLX1B
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chr6_+_2710560 0.268 WRNIP1
Werner helicase interacting protein 1
chr3_+_5204310 0.268 EDEM1
ER degradation enhancer, mannosidase alpha-like 1
chr2_+_236067687 0.268 AGAP1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr20_+_60246982 0.268 OSBPL2
oxysterol binding protein-like 2
chr4_+_186554831 0.268 NM_181726
ANKRD37
ankyrin repeat domain 37
chr3_+_40473785 0.267 NM_003973
NM_001034996
RPL14

ribosomal protein L14

chr3_+_5204430 0.267 EDEM1
ER degradation enhancer, mannosidase alpha-like 1
chr2_+_108517356 0.265 LIMS1
LIM and senescent cell antigen-like domains 1
chr20_-_60151802 0.265 PSMA7
proteasome (prosome, macropain) subunit, alpha type, 7
chr14_+_96038451 0.265 NM_032632
PAPOLA
poly(A) polymerase alpha
chr20_+_60246971 0.264 OSBPL2
oxysterol binding protein-like 2
chr2_+_74502364 0.264 NM_032118
WDR54
WD repeat domain 54
chr4_+_56997025 0.263 NM_001079524
NM_001079525
PAICS

phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase

chr18_+_9904060 0.263 VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr2_+_108517239 0.262 NM_001193483
LIMS1
LIM and senescent cell antigen-like domains 1
chr12_+_68923477 0.262 CNOT2
CCR4-NOT transcription complex, subunit 2
chr5_+_138637339 0.262 NM_001194954
NM_199189
MATR3

matrin 3

chr11_+_113776582 0.261 NM_016090
RBM7
RNA binding motif protein 7
chr16_-_47201588 0.261 NM_153029
N4BP1
NEDD4 binding protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.30 1.64e-14 GO:0044237 cellular metabolic process
1.23 8.55e-11 GO:0008152 metabolic process
1.34 1.82e-10 GO:0044260 cellular macromolecule metabolic process
1.13 1.09e-09 GO:0009987 cellular process
1.25 1.18e-09 GO:0044238 primary metabolic process
1.27 2.07e-07 GO:0043170 macromolecule metabolic process
1.36 7.04e-05 GO:0044267 cellular protein metabolic process
1.31 7.48e-05 GO:0034641 cellular nitrogen compound metabolic process
1.37 7.85e-05 GO:0048519 negative regulation of biological process
1.33 8.43e-05 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.30 1.06e-04 GO:0006807 nitrogen compound metabolic process
1.38 2.23e-04 GO:0048523 negative regulation of cellular process
1.35 2.36e-04 GO:0044249 cellular biosynthetic process
1.34 3.44e-04 GO:0009058 biosynthetic process
1.38 1.98e-03 GO:0010467 gene expression
1.34 2.48e-03 GO:0090304 nucleic acid metabolic process
1.36 6.19e-03 GO:0006464 protein modification process
1.27 7.22e-03 GO:0019538 protein metabolic process
1.53 9.43e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.34 9.95e-03 GO:0043412 macromolecule modification
1.50 1.16e-02 GO:0009892 negative regulation of metabolic process
1.27 1.38e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.36 1.61e-02 GO:0016070 RNA metabolic process
1.35 2.64e-02 GO:0009059 macromolecule biosynthetic process
1.35 2.78e-02 GO:0034645 cellular macromolecule biosynthetic process
1.26 4.08e-02 GO:0071842 cellular component organization at cellular level

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.18 1.32e-21 GO:0044424 intracellular part
1.17 2.52e-20 GO:0005622 intracellular
1.22 4.93e-16 GO:0043231 intracellular membrane-bounded organelle
1.22 7.24e-16 GO:0043227 membrane-bounded organelle
1.17 2.44e-12 GO:0043226 organelle
1.17 3.16e-12 GO:0043229 intracellular organelle
1.20 1.41e-11 GO:0005737 cytoplasm
1.27 3.46e-10 GO:0005634 nucleus
1.27 3.52e-10 GO:0044446 intracellular organelle part
1.26 1.26e-09 GO:0044422 organelle part
1.45 4.32e-08 GO:0044428 nuclear part
1.22 1.44e-07 GO:0044444 cytoplasmic part
1.05 8.65e-06 GO:0044464 cell part
1.05 8.98e-06 GO:0005623 cell
1.37 1.04e-05 GO:0070013 intracellular organelle lumen
1.38 1.76e-05 GO:0031090 organelle membrane
1.36 1.84e-05 GO:0043233 organelle lumen
1.36 2.36e-05 GO:0031974 membrane-enclosed lumen
1.43 4.09e-05 GO:0012505 endomembrane system
2.16 1.51e-04 GO:0005635 nuclear envelope
1.35 2.40e-04 GO:0005829 cytosol
1.37 2.89e-04 GO:0031981 nuclear lumen
1.57 2.16e-03 GO:0031967 organelle envelope
1.56 2.62e-03 GO:0031975 envelope
2.20 1.80e-02 GO:0031965 nuclear membrane
2.04 2.65e-02 GO:0031252 cell leading edge
2.49 4.72e-02 GO:0001726 ruffle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.22 1.49e-10 GO:0005515 protein binding
1.10 2.32e-07 GO:0005488 binding
1.18 1.82e-03 GO:0003824 catalytic activity
1.36 1.93e-03 GO:0016740 transferase activity
1.29 6.65e-03 GO:0000166 nucleotide binding
1.21 2.75e-02 GO:0003676 nucleic acid binding