Motif ID: IKZF2.p2

Z-value: 1.750


Transcription factors associated with IKZF2.p2:

Gene SymbolEntrez IDGene Name
IKZF2 22807 IKAROS family zinc finger 2 (Helios)



Activity profile for motif IKZF2.p2.

activity profile for motif IKZF2.p2


Sorted Z-values histogram for motif IKZF2.p2

Sorted Z-values for motif IKZF2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of IKZF2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_32698892 2.912 NM_001159996
NRG1
neuregulin 1
chr4_-_153523113 2.630 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr11_+_101488380 2.619 NM_001195045
YAP1
Yes-associated protein 1
chr3_+_99465777 2.590 NM_001005479
OR5H6
olfactory receptor, family 5, subfamily H, member 6
chr6_+_127940011 2.455 NM_001010905
C6orf58
chromosome 6 open reading frame 58
chr14_-_105862080 2.444 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG2
IGHG3
IGHM
SCFV
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
single-chain Fv fragment
chr14_-_106064887 2.266 LOC100126583
IGHV3-48
IGHA1
IGHM
hypothetical LOC100126583
immunoglobulin heavy variable 3-48
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr14_+_38719462 2.240 PNN
pinin, desmosome associated protein
chr7_+_93388951 2.183 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr1_+_150852910 2.100 NM_178433
LCE3B
late cornified envelope 3B
chr2_+_228386800 2.005 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr6_-_109795925 1.967 CD164
CD164 molecule, sialomucin
chr14_+_38720085 1.957 PNN
pinin, desmosome associated protein
chr6_+_153113624 1.953 NM_003381
NM_194435
VIP

vasoactive intestinal peptide

chr7_+_17304707 1.902 NM_001621
AHR
aryl hydrocarbon receptor
chr14_+_31615959 1.846 ARHGAP5
Rho GTPase activating protein 5
chr2_-_215967442 1.838 FN1
fibronectin 1
chr9_-_106401514 1.832 NM_001004482
OR13C5
olfactory receptor, family 13, subfamily C, member 5
chr14_+_64001969 1.826 NM_004857
AKAP5
A kinase (PRKA) anchor protein 5
chr4_+_95595419 1.756 PDLIM5
PDZ and LIM domain 5
chr11_-_95715976 1.679 NM_032427
MAML2
mastermind-like 2 (Drosophila)
chr4_+_124540114 1.673 NM_005841
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr2_-_210888010 1.665 NM_079420
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr14_+_31615922 1.657 ARHGAP5
Rho GTPase activating protein 5
chr13_+_81162030 1.640


chr5_-_146441184 1.639 NM_181677
NM_181678
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr14_-_20969706 1.605 NM_001170629
CHD8
chromodomain helicase DNA binding protein 8
chr12_-_11178109 1.593 NM_001097643
TAS2R30
taste receptor, type 2, member 30
chr6_+_88024152 1.591 ZNF292
zinc finger protein 292
chr14_-_94669547 1.569 NM_001195573
DICER1
dicer 1, ribonuclease type III
chr18_+_27281729 1.549 NM_001944
DSG3
desmoglein 3
chr5_+_27508139 1.533 LOC643401
hypothetical protein LOC643401
chr6_-_127882192 1.532 NM_001012279
C6orf174
chromosome 6 open reading frame 174
chr2_+_191009265 1.532 MFSD6
major facilitator superfamily domain containing 6
chr14_-_105589467 1.528 LOC100126583
IGHA1
IGHG1
IGHG2
IGHM
hypothetical LOC100126583
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant mu
chr2_-_225073357 1.519 CUL3
cullin 3
chr6_+_129245978 1.515 NM_000426
NM_001079823
LAMA2

laminin, alpha 2

chr9_+_12764988 1.508 NM_203403
C9orf150
chromosome 9 open reading frame 150
chr9_-_21375258 1.495 NM_000605
IFNA2
interferon, alpha 2
chr10_+_112669353 1.495 SHOC2
soc-2 suppressor of clear homolog (C. elegans)
chr10_+_90336489 1.489 NM_001010939
LIPJ
lipase, family member J
chr14_-_106193403 1.484 IGKV3-20
immunoglobulin kappa variable 3-20
chr14_+_22059212 1.474


chr7_+_80145461 1.467 CD36
CD36 molecule (thrombospondin receptor)
chr11_+_27019084 1.450 NM_003986
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr3_+_186563529 1.447 NM_004721
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr2_-_40593074 1.438 NM_001112802
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr2_+_114390975 1.425 ACTR3
ARP3 actin-related protein 3 homolog (yeast)
chr10_+_112669349 1.384 SHOC2
soc-2 suppressor of clear homolog (C. elegans)
chr17_-_36451189 1.380 NM_030967
KRTAP1-3
KRTAP1-1
keratin associated protein 1-3
keratin associated protein 1-1
chr1_-_246503738 1.379 NM_001004695
OR2T33
olfactory receptor, family 2, subfamily T, member 33
chr1_-_246554492 1.360 NM_001004691
OR2M7
olfactory receptor, family 2, subfamily M, member 7
chr17_-_26648375 1.360 NM_002544
OMG
oligodendrocyte myelin glycoprotein
chr7_-_22518200 1.352 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr12_-_51153788 1.351 NM_173086
KRT6C
keratin 6C
chr6_-_68655708 1.349


chr9_+_112470871 1.341 NM_001166280
NM_001166281
NM_005592
MUSK


muscle, skeletal, receptor tyrosine kinase


chr5_-_147191428 1.340 NM_003122
SPINK1
serine peptidase inhibitor, Kazal type 1
chr1_-_150564302 1.337 NM_002016
FLG
filaggrin
chr7_+_94135384 1.333 PEG10
paternally expressed 10
chr20_-_17589122 1.324 RRBP1
ribosome binding protein 1 homolog 180kDa (dog)
chr17_-_36376663 1.320 NM_213656
KRT39
keratin 39
chr18_+_30544193 1.317 NM_001198941
NM_032978
DTNA

dystrobrevin, alpha

chr9_-_72673753 1.312 NM_001007470
NM_020952
NM_024971
NM_206944
NM_206945
NM_206946
NM_206947
NM_206948
TRPM3







transient receptor potential cation channel, subfamily M, member 3







chr14_-_31026901 1.299 NM_001197184
GPR33
G protein-coupled receptor 33 (gene/pseudogene)
chr11_-_89248832 1.297 NM_001164397
TRIM64B
tripartite motif containing 64B
chr9_-_21358005 1.263 NM_006900
IFNA1
IFNA13
interferon, alpha 1
interferon, alpha 13
chr14_+_74353417 1.259 YLPM1
YLP motif containing 1
chr5_-_86739683 1.257 CCNH
cyclin H
chr5_-_147191334 1.253 SPINK1
serine peptidase inhibitor, Kazal type 1
chr10_+_63092724 1.251 NM_173554
C10orf107
chromosome 10 open reading frame 107
chr14_+_55148488 1.249 KTN1
kinectin 1 (kinesin receptor)
chr6_+_53043729 1.249 NM_012347
FBXO9
F-box protein 9
chr11_-_5178505 1.238 NM_001004760
OR51V1
olfactory receptor, family 51, subfamily V, member 1
chr13_+_49658016 1.234


chr10_-_98280299 1.210 TM9SF3
transmembrane 9 superfamily member 3
chr13_-_32678142 1.208 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr6_+_64414389 1.201 NM_015153
PHF3
PHD finger protein 3
chr12_-_11075272 1.195 NM_176885
TAS2R31
taste receptor, type 2, member 31
chr1_+_39569396 1.195 NM_033044
MACF1
microtubule-actin crosslinking factor 1
chr14_-_106184988 1.194 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr11_+_56187713 1.190 NM_001004730
OR5AR1
olfactory receptor, family 5, subfamily AR, member 1
chr1_+_93317374 1.187 NM_001164391
NM_001164392
NM_001164393
NM_007358
MTF2



metal response element binding transcription factor 2



chr2_+_192251105 1.186 NM_001031716
OBFC2A
oligonucleotide/oligosaccharide-binding fold containing 2A
chr7_+_111879348 1.184 NM_001197079
IFRD1
interferon-related developmental regulator 1
chr11_+_89341319 1.184 NM_001136486
TRIM64
tripartite motif containing 64
chr9_+_122890394 1.178 NM_007018
CEP110
centrosomal protein 110kDa
chr1_+_157067729 1.174 NM_002432
MNDA
myeloid cell nuclear differentiation antigen
chr10_-_113933457 1.172 NM_020918
GPAM
glycerol-3-phosphate acyltransferase, mitochondrial
chr10_-_121592020 1.171 MCMBP
minichromosome maintenance complex binding protein
chr14_+_22059174 1.169


chr14_-_105763152 1.168 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG3
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr10_+_86121526 1.161 FAM190B
family with sequence similarity 190, member B
chr5_+_65476418 1.161 NM_139168
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr22_+_29696662 1.160


chr4_-_122357104 1.159 NM_001128843
TNIP3
TNFAIP3 interacting protein 3
chr12_-_11041740 1.155 NM_176889
TAS2R20
taste receptor, type 2, member 20
chr4_-_120462705 1.155 NM_000134
FABP2
fatty acid binding protein 2, intestinal
chr5_+_140160966 1.155 NM_018906
NM_031497
PCDHA3

protocadherin alpha 3

chr18_+_3443771 1.150 NM_173211
TGIF1
TGFB-induced factor homeobox 1
chr19_+_41419165 1.141 ZNF146
zinc finger protein 146
chr3_+_180348818 1.140 NM_006218
PIK3CA
phosphoinositide-3-kinase, catalytic, alpha polypeptide
chr21_+_30937053 1.136 NM_001128077
KRTAP20-3
keratin associated protein 20-3
chr5_-_101862447 1.124 NM_173488
SLCO6A1
solute carrier organic anion transporter family, member 6A1
chr13_+_19430881 1.120 ZMYM2
zinc finger, MYM-type 2
chr13_-_101852028 1.113 NM_175929
FGF14
fibroblast growth factor 14
chr14_+_98247702 1.108 NM_182560
C14orf177
chromosome 14 open reading frame 177
chr5_+_43645018 1.104 NNT
nicotinamide nucleotide transhydrogenase
chr11_+_33306652 1.103 HIPK3
homeodomain interacting protein kinase 3
chr1_-_115070413 1.103 CSDE1
cold shock domain containing E1, RNA-binding
chr2_-_231697999 1.094 NM_000867
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B
chr12_-_12182641 1.086 LRP6
low density lipoprotein receptor-related protein 6
chrX_+_56772391 1.086 LOC550643
hypothetical LOC550643
chr11_+_11820096 1.085 USP47
ubiquitin specific peptidase 47
chr21_-_26294332 1.084 APP
amyloid beta (A4) precursor protein
chr1_-_196776697 1.078 NM_133262
NM_133326
ATP6V1G3

ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3

chr11_-_6005546 1.078 NM_001001917
OR56A1
olfactory receptor, family 56, subfamily A, member 1
chr4_-_101658094 1.070 NM_001159694
NM_016242
EMCN

endomucin

chr5_-_151764857 1.068 NM_020167
NMUR2
neuromedin U receptor 2
chr6_-_11887265 1.068 NM_001143948
NM_032744
C6orf105

chromosome 6 open reading frame 105

chr9_+_124416768 1.063 NM_012364
OR1Q1
olfactory receptor, family 1, subfamily Q, member 1
chr4_+_144654526 1.062


chr10_+_112669267 1.061 NM_007373
SHOC2
soc-2 suppressor of clear homolog (C. elegans)
chr17_+_36642240 1.060 NM_031962
KRTAP9-9
KRTAP9-3
keratin associated protein 9-9
keratin associated protein 9-3
chr13_+_48448950 1.060 FNDC3A
fibronectin type III domain containing 3A
chr14_-_20694023 1.058 NM_001004731
OR5AU1
olfactory receptor, family 5, subfamily AU, member 1
chr22_-_39189369 1.047 MKL1
megakaryoblastic leukemia (translocation) 1
chr18_-_35634247 1.045 LOC647946
hypothetical LOC647946
chr13_+_48448912 1.042 FNDC3A
fibronectin type III domain containing 3A
chr12_+_58369392 1.042 NM_004731
SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr1_-_246823691 1.040 NM_001004693
OR2T10
olfactory receptor, family 2, subfamily T, member 10
chr9_+_74956494 1.035 NM_000700
ANXA1
annexin A1
chr13_+_48582389 1.034 NM_014923
FNDC3A
fibronectin type III domain containing 3A
chr7_-_14847479 1.032 NM_004080
NM_145695
DGKB

diacylglycerol kinase, beta 90kDa

chr3_-_52688768 1.030 NM_018165
NM_181042
PBRM1

polybromo 1

chr12_+_77963563 1.022 NM_001135806
SYT1
synaptotagmin I
chr2_-_21079145 1.017 APOB
apolipoprotein B (including Ag(x) antigen)
chr6_+_132901119 1.016 NM_175057
TAAR9
trace amine associated receptor 9 (gene/pseudogene)
chr10_+_129237602 1.016 NM_001030013
NPS
neuropeptide S
chr3_+_73193499 1.012 NM_018029
EBLN2
endogenous Borna-like N element-2
chr21_-_30720100 1.007 NM_181622
KRTAP13-3
keratin associated protein 13-3
chr8_-_82522175 1.007 NM_002677
PMP2
peripheral myelin protein 2
chr10_+_106003941 1.006 NM_001191003
GSTO1
glutathione S-transferase omega 1
chr17_+_23394062 1.005 NLK
nemo-like kinase
chr7_+_93862137 1.005 COL1A2
PLAG1
collagen, type I, alpha 2
pleiomorphic adenoma gene 1
chr13_+_48448628 1.001 FNDC3A
fibronectin type III domain containing 3A
chr6_-_128883125 1.001 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr6_-_26343139 0.994 NM_005320
HIST1H1D
histone cluster 1, H1d
chr17_-_3142625 0.993 NM_002550
OR3A1
olfactory receptor, family 3, subfamily A, member 1
chr21_-_26345294 0.990


chr9_-_114814286 0.988 NM_001101338
ZNF883
zinc finger protein 883
chr3_-_71715431 0.986 NM_001012505
NM_032682
FOXP1

forkhead box P1

chr2_-_213723298 0.986 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr9_-_28709302 0.985 NM_152570
LINGO2
leucine rich repeat and Ig domain containing 2
chr12_-_88573949 0.978 NM_001001323
NM_001682
ATP2B1

ATPase, Ca++ transporting, plasma membrane 1

chr10_+_96433240 0.973 NM_000772
NM_001128925
CYP2C18

cytochrome P450, family 2, subfamily C, polypeptide 18

chr10_-_98311813 0.972 TM9SF3
transmembrane 9 superfamily member 3
chr14_-_105785639 0.971


chr1_-_21310462 0.962 NM_003760
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr16_+_31105579 0.959


chr12_+_7348194 0.955 NM_001080454
ACSM4
acyl-CoA synthetase medium-chain family member 4
chr8_+_120289735 0.952 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr4_+_25931745 0.944 RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr13_+_23042722 0.943 NM_148957
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr11_+_55776251 0.941 NM_001004747
OR5T3
olfactory receptor, family 5, subfamily T, member 3
chr1_-_246869181 0.926 NM_001001827
OR2T35
olfactory receptor, family 2, subfamily T, member 35
chr10_+_102285690 0.924 HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr2_-_189363075 0.924 NM_052952
DIRC1
disrupted in renal carcinoma 1
chr1_+_42934910 0.923 YBX1
Y box binding protein 1
chr17_+_12564330 0.921 NM_001146313
MYOCD
myocardin
chr11_+_113815317 0.920 NM_015523
REXO2
REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chr9_-_14900992 0.920 NM_144966
FREM1
FRAS1 related extracellular matrix 1
chr17_+_36636404 0.920 NM_031961
KRTAP9-2
keratin associated protein 9-2
chr7_+_91762227 0.916


chr5_+_140235114 0.914 NM_018903
NM_031864
PCDHA12

protocadherin alpha 12

chr18_-_46600295 0.914 NM_001127175
NM_001127176
NM_031939
MRO


maestro


chr10_-_112668679 0.913 NM_001195306
BBIP1
BBSome interacting protein 1
chr9_+_70046658 0.913 NM_201453
CBWD5
CBWD3
CBWD1
CBWD6
COBW domain containing 5
COBW domain containing 3
COBW domain containing 1
COBW domain containing 6
chr9_+_108665168 0.912 NM_021224
ZNF462
zinc finger protein 462
chr2_-_49235059 0.906 NM_000145
NM_181446
FSHR

follicle stimulating hormone receptor

chr9_-_21192201 0.905 NM_021057
IFNA7
interferon, alpha 7
chr7_-_18033970 0.905 NM_175886
PRPS1L1
phosphoribosyl pyrophosphate synthetase 1-like 1
chr17_+_23393744 0.903 NM_016231
NLK
nemo-like kinase
chr14_+_85066265 0.903 FLRT2
fibronectin leucine rich transmembrane protein 2
chr16_+_10430225 0.893 NM_024997
ATF7IP2
activating transcription factor 7 interacting protein 2
chr11_+_55297489 0.888 NM_001001967
OR5D13
olfactory receptor, family 5, subfamily D, member 13
chr7_-_122627235 0.886 NM_022444
SLC13A1
solute carrier family 13 (sodium/sulfate symporters), member 1
chr15_-_75259714 0.882 PEAK1
NKF3 kinase family member
chr14_-_22549168 0.882 NM_001130706
NM_001130708
NM_021944
C14orf93


chromosome 14 open reading frame 93


chr1_-_171838802 0.882 NM_178527
SLC9A11
solute carrier family 9, member 11
chr4_+_71054492 0.873 NM_214711
C4orf40
chromosome 4 open reading frame 40
chr1_+_40399618 0.871 NM_012421
RLF
rearranged L-myc fusion
chr8_-_17812151 0.869


chr20_-_33783409 0.868 RBM39
RNA binding motif protein 39
chr11_+_109468734 0.865 ZC3H12C
zinc finger CCCH-type containing 12C
chr1_+_40399642 0.862 RLF
rearranged L-myc fusion
chr4_+_74520796 0.862 NM_001134
AFP
alpha-fetoprotein
chr2_-_210876560 0.861 NM_079422
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr19_+_41418723 0.856 ZNF146
zinc finger protein 146
chr11_-_62753574 0.854 NM_199352
SLC22A25
solute carrier family 22, member 25

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.57 1.60e-28 GO:0007606 sensory perception of chemical stimulus
2.66 5.95e-28 GO:0007608 sensory perception of smell
1.85 8.02e-16 GO:0007600 sensory perception
1.58 7.04e-13 GO:0050877 neurological system process
1.46 2.32e-10 GO:0003008 system process
1.15 2.35e-05 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.17 5.06e-04 GO:0071944 cell periphery
1.17 5.94e-04 GO:0005886 plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.73 2.35e-29 GO:0004984 olfactory receptor activity
1.84 1.32e-16 GO:0004930 G-protein coupled receptor activity
1.53 1.92e-10 GO:0004888 transmembrane receptor activity
1.40 4.44e-08 GO:0004872 receptor activity
1.32 3.43e-06 GO:0004871 signal transducer activity
1.32 3.43e-06 GO:0060089 molecular transducer activity