Motif ID: KLF12.p2

Z-value: 1.953


Transcription factors associated with KLF12.p2:

Gene SymbolEntrez IDGene Name
KLF12 11278 Kruppel-like factor 12



Activity profile for motif KLF12.p2.

activity profile for motif KLF12.p2


Sorted Z-values histogram for motif KLF12.p2

Sorted Z-values for motif KLF12.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF12.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_14121728 7.659 LPHN1
latrophilin 1
chr19_+_2200112 6.126 NM_000479
AMH
anti-Mullerian hormone
chr19_-_3928516 5.995 EEF2
eukaryotic translation elongation factor 2
chrX_+_67965517 5.621 NM_004429
EFNB1
ephrin-B1
chr16_-_66535457 5.349 NM_000229
LCAT
lecithin-cholesterol acyltransferase
chrX_+_152454773 5.189 NM_001001344
NM_021949
ATP2B3

ATPase, Ca++ transporting, plasma membrane 3

chr19_+_16005929 4.997 FLJ25328
hypothetical LOC148231
chr16_+_67697622 4.934 NM_138612
HAS3
hyaluronan synthase 3
chr16_-_66535923 4.757 SLC12A4
solute carrier family 12 (potassium/chloride transporters), member 4
chr1_+_23990228 4.729 NM_007260
LYPLA2
lysophospholipase II
chr17_+_24095135 4.719 NM_004295
TRAF4
TNF receptor-associated factor 4
chrX_+_152699616 4.702 NM_001170760
NM_001170761
NM_014370
SRPK3


SRSF protein kinase 3


chr2_+_232281491 4.695 PTMA
prothymosin, alpha
chr19_+_5641307 4.663 RPL36
ribosomal protein L36
chr5_+_137829065 4.643 EGR1
early growth response 1
chr17_-_1495742 4.612 NM_003693
NM_145350
NM_145352
SCARF1


scavenger receptor class F, member 1


chr19_+_5641270 4.566 NM_033643
RPL36
ribosomal protein L36
chr9_-_129752687 4.504 NM_203305
FAM102A
family with sequence similarity 102, member A
chr19_+_5641332 4.454 NM_015414
RPL36
ribosomal protein L36
chr20_+_61394982 4.322 NM_020882
COL20A1
collagen, type XX, alpha 1
chr2_+_232281470 4.243 NM_001099285
NM_002823
PTMA

prothymosin, alpha

chr11_+_1607580 4.187 NM_001001480
KRTAP5-5
keratin associated protein 5-5
chr5_+_137829077 4.174 NM_001964
EGR1
early growth response 1
chr12_+_52665196 4.161 NM_017409
HOXC10
homeobox C10
chr1_+_1256585 4.138 NM_152228
TAS1R3
taste receptor, type 1, member 3
chr16_+_1246273 4.040 NM_012217
TPSD1
tryptase delta 1
chr16_+_31132842 4.004 NM_001008274
TRIM72
tripartite motif containing 72
chr19_+_2173415 3.965 DOT1L
DOT1-like, histone H3 methyltransferase (S. cerevisiae)
chr15_-_70288071 3.964 PKM2
pyruvate kinase, muscle
chr1_+_32512298 3.936 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr15_+_65904994 3.742 NM_001031807
SKOR1
SKI family transcriptional corepressor 1
chr1_+_1099145 3.666 NM_001130045
TTLL10
tubulin tyrosine ligase-like family, member 10
chr8_-_140784416 3.580 NM_016601
KCNK9
potassium channel, subfamily K, member 9
chr10_+_80672842 3.569 ZMIZ1
zinc finger, MIZ-type containing 1
chr19_-_7840806 3.472 FLJ22184
hypothetical protein FLJ22184
chr7_+_100113664 3.454 GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr19_+_2427122 3.452 NM_015675
GADD45B
growth arrest and DNA-damage-inducible, beta
chr1_+_109594163 3.408 NM_001408
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr20_+_44070946 3.267 NM_004994
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr11_-_70971556 3.261 NM_001005405
KRTAP5-11
keratin associated protein 5-11
chr12_-_51233001 3.251 NM_033448
KRT71
keratin 71
chr11_+_65164767 3.192 SIPA1
signal-induced proliferation-associated 1
chr16_-_2099854 3.142 PKD1
polycystic kidney disease 1 (autosomal dominant)
chr1_+_201541241 3.122 BTG2
BTG family, member 2
chr17_-_7036490 3.095


chr6_+_108593907 3.050 NM_003269
NR2E1
nuclear receptor subfamily 2, group E, member 1
chr1_-_1171964 3.033 NM_001014980
FAM132A
family with sequence similarity 132, member A
chr11_+_66381451 3.032 NM_024036
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr1_+_31823097 2.995 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr17_+_71235324 2.994 ITGB4
integrin, beta 4
chr20_+_61337679 2.986 NM_022161
NM_139317
BIRC7

baculoviral IAP repeat containing 7

chr1_+_16247870 2.985 NM_001165945
CLCNKB
chloride channel Kb
chr3_-_12916547 2.969 IQSEC1
IQ motif and Sec7 domain 1
chrX_+_46967360 2.911 NM_001170460
CDK16
cyclin-dependent kinase 16
chr11_+_65164963 2.905


chr2_+_104837004 2.876


chr8_-_6407882 2.868 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr9_-_138378061 2.865 NM_001080849
DNLZ
DNL-type zinc finger
chr11_+_118259684 2.848 NM_001716
CXCR5
chemokine (C-X-C motif) receptor 5
chr9_+_139255519 2.844 NM_006088
TUBB2C
tubulin, beta 2C
chr10_+_104394185 2.807 NM_030912
TRIM8
tripartite motif containing 8
chr16_+_2959342 2.766 NM_152341
PAQR4
progestin and adipoQ receptor family member IV
chr17_-_76064842 2.751 NM_002522
NPTX1
neuronal pentraxin I
chr16_+_30583599 2.741 FBRS
fibrosin
chr9_+_138367329 2.740 NM_001145639
GPSM1
G-protein signaling modulator 1
chr16_+_2959362 2.729 PAQR4
progestin and adipoQ receptor family member IV
chr4_+_2031036 2.679 NM_178557
NAT8L
N-acetyltransferase 8-like (GCN5-related, putative)
chr1_+_201541269 2.659 NM_006763
BTG2
BTG family, member 2
chr6_+_29799182 2.577 HLA-F
major histocompatibility complex, class I, F
chr19_+_1892157 2.576 NM_001319
CSNK1G2
casein kinase 1, gamma 2
chr22_+_18499354 2.560 NM_001185024
NM_013373
ZDHHC8

zinc finger, DHHC-type containing 8

chr8_-_29262240 2.559 NM_057158
DUSP4
dual specificity phosphatase 4
chr12_+_111980044 2.558 NM_004416
DTX1
deltex homolog 1 (Drosophila)
chr11_-_1464386 2.555 NM_001172223
MOB2
Mps one binder kinase activator-like 2
chr8_+_143758875 2.525 NM_005672
PSCA
prostate stem cell antigen
chr15_-_68128924 2.500 TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chrX_+_151837064 2.487 NM_001178113
ZNF185
zinc finger protein 185 (LIM domain)
chr1_+_48460943 2.473 NM_001011547
NM_001135181
SLC5A9

solute carrier family 5 (sodium/glucose cotransporter), member 9

chr1_-_1840564 2.463 NM_178545
TMEM52
transmembrane protein 52
chr8_-_145609737 2.448 SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr3_-_130761967 2.400 PLXND1
plexin D1
chr9_+_34642125 2.382 NM_001142784
IL11RA
interleukin 11 receptor, alpha
chr11_-_1731273 2.373


chr11_+_63876924 2.372 CCDC88B
coiled-coil domain containing 88B
chr11_-_1576057 2.365 NM_001004325
KRTAP5-2
keratin associated protein 5-2
chr9_+_139292094 2.359 NM_017723
C9orf167
chromosome 9 open reading frame 167
chr1_+_968522 2.356 AGRN
agrin
chr14_+_103675194 2.350 KIF26A
kinesin family member 26A
chr19_-_55912006 2.348 NM_016148
SHANK1
SH3 and multiple ankyrin repeat domains 1
chr11_+_63864263 2.345 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr6_+_37030186 2.342 NM_153370
PI16
peptidase inhibitor 16
chr17_-_77092569 2.318 ACTG1
actin, gamma 1
chr19_+_590878 2.303 NM_020637
FGF22
fibroblast growth factor 22
chr16_+_1062756 2.297 NM_001172560
SSTR5
somatostatin receptor 5
chrX_+_69581429 2.277 NM_021120
DLG3
discs, large homolog 3 (Drosophila)
chr11_-_2108035 2.268 IGF2
insulin-like growth factor 2 (somatomedin A)
chr17_+_71141108 2.246 NM_001162995
LOC643008
hypothetical protein LOC643008
chr16_+_30583278 2.234 NM_001105079
FBRS
fibrosin
chr1_-_201321711 2.225 MYOG
myogenin (myogenic factor 4)
chr2_+_241279934 2.219 NM_198998
AQP12A
AQP12B
aquaporin 12A
aquaporin 12B
chr19_-_41034734 2.213 NM_004646
NPHS1
nephrosis 1, congenital, Finnish type (nephrin)
chr17_+_7125702 2.204 NM_001042
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
chr1_-_201321999 2.200 NM_002479
MYOG
myogenin (myogenic factor 4)
chr16_+_751050 2.200 NM_013404
MSLN
mesothelin
chr17_-_1029758 2.191 NM_021962
ABR
active BCR-related gene
chr19_-_50975121 2.190


chr9_+_139006663 2.189 NM_183241
C9orf142
chromosome 9 open reading frame 142
chr8_-_145119627 2.188 NM_201378
PLEC
plectin
chr1_-_232810111 2.175 IRF2BP2
interferon regulatory factor 2 binding protein 2
chr1_+_44643513 2.172 NM_018150
RNF220
ring finger protein 220
chr17_-_1342700 2.171 NM_001080779
MYO1C
myosin IC
chr16_+_2959467 2.164 PAQR4
progestin and adipoQ receptor family member IV
chr17_-_40839082 2.153 NM_001159330
ARHGAP27
Rho GTPase activating protein 27
chr6_+_160462852 2.140 NM_003057
NM_153187
SLC22A1

solute carrier family 22 (organic cation transporter), member 1

chr19_+_38389799 2.108 LRP3
low density lipoprotein receptor-related protein 3
chr17_-_34084682 2.074 NM_001130677
C17orf96
chromosome 17 open reading frame 96
chr9_-_129573330 2.067 NM_005489
SH2D3C
SH2 domain containing 3C
chr16_+_162845 2.062 NM_000517
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr22_+_29817218 2.052 SMTN
smoothelin
chr17_+_35075124 2.045 NM_003673
TCAP
titin-cap (telethonin)
chr1_+_945472 2.043 AGRN
agrin
chr7_+_27248688 2.024 NM_001989
EVX1
even-skipped homeobox 1
chr9_+_132002692 2.016 NM_001128826
NCS1
neuronal calcium sensor 1
chr11_-_117589283 2.015 NM_153206
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr9_-_139027435 2.014 ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr19_-_50963942 2.009


chr16_+_2503915 2.004 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr17_-_77092831 1.999 ACTG1
actin, gamma 1
chr11_-_1006736 1.995 MUC6
mucin 6, oligomeric mucus/gel-forming
chr21_+_44530148 1.979 NM_000383
AIRE
autoimmune regulator
chr19_+_5865192 1.966 NM_004058
NM_080590
CAPS

calcyphosine

chr17_-_78391178 1.954 NM_024702
ZNF750
zinc finger protein 750
chr8_+_21956335 1.947 NM_003867
FGF17
fibroblast growth factor 17
chr17_-_35331435 1.940 ORMDL3
ORM1-like 3 (S. cerevisiae)
chr11_-_118716244 1.939 MFRP
membrane frizzled-related protein
chr17_-_45617899 1.933 COL1A1
collagen, type I, alpha 1
chr11_+_64737886 1.932 NM_001004326
SLC22A20
solute carrier family 22, member 20
chr1_-_199348316 1.931 NM_000069
CACNA1S
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr19_+_50963484 1.928


chrX_-_106033202 1.928 NM_001171706
NM_138382
RIPPLY1

ripply1 homolog (zebrafish)

chr6_+_31706345 1.926 PRRC2A
proline-rich coiled-coil 2A
chr19_-_3928840 1.922 EEF2
eukaryotic translation elongation factor 2
chr19_-_2668272 1.919 DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr15_+_39573363 1.909 NM_002220
ITPKA
inositol 1,4,5-trisphosphate 3-kinase A
chr1_-_46789473 1.902 NM_001097611
KNCN
kinocilin
chr1_+_203106600 1.901 NFASC
neurofascin
chr22_+_29817315 1.898 SMTN
smoothelin
chr15_-_75694674 1.896 LINGO1
leucine rich repeat and Ig domain containing 1
chr13_-_78075683 1.895 NM_006237
POU4F1
POU class 4 homeobox 1
chr17_+_77925441 1.893 NM_018949
UTS2R
urotensin 2 receptor
chr8_-_142446546 1.891 NM_005293
GPR20
G protein-coupled receptor 20
chr11_+_60448487 1.886 NM_017870
NM_178031
TMEM132A

transmembrane protein 132A

chr20_+_29598848 1.878 HM13
histocompatibility (minor) 13
chr5_+_149717489 1.877 TCOF1
Treacher Collins-Franceschetti syndrome 1
chr7_+_100111712 1.876 GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr1_+_157441824 1.873 NM_001122951
DARC
Duffy blood group, chemokine receptor
chr8_-_145097031 1.867 NM_201380
PLEC
plectin
chr11_-_1599900 1.860 NM_001012709
KRTAP5-4
keratin associated protein 5-4
chr9_+_138991775 1.858 NM_000954
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr17_+_19255083 1.853 NM_007148
RNF112
ring finger protein 112
chr19_+_10689772 1.851 DNM2
dynamin 2
chr16_+_1299361 1.844 NM_194260
UBE2I
ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)
chr10_+_88404285 1.843 NM_001030015
NM_033282
OPN4

opsin 4

chr1_-_37991160 1.842 EPHA10
EPH receptor A10
chr1_+_891739 1.835 NM_001160184
NM_032129
PLEKHN1

pleckstrin homology domain containing, family N member 1

chr9_+_139255559 1.824 TUBB2C
tubulin, beta 2C
chr17_+_4743645 1.824 NM_001145536
C17orf107
chromosome 17 open reading frame 107
chr17_+_45617676 1.819


chr16_+_1299180 1.819 NM_194261
UBE2I
ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)
chr14_+_104238713 1.818 INF2
inverted formin, FH2 and WH2 domain containing
chr10_+_80740584 1.799 ZMIZ1
zinc finger, MIZ-type containing 1
chr6_+_41714171 1.793 NM_005586
MDFI
MyoD family inhibitor
chr17_-_32368033 1.791


chr17_-_975809 1.783 ABR
active BCR-related gene
chr2_+_220017617 1.776 SPEG
SPEG complex locus
chr9_+_130124566 1.774 NM_016035
COQ4
coenzyme Q4 homolog (S. cerevisiae)
chr19_+_54883732 1.767 NM_001101340
C19orf76
chromosome 19 open reading frame 76
chr9_+_139255563 1.759 TUBB2C
tubulin, beta 2C
chr5_+_159276317 1.756 NM_000679
ADRA1B
adrenergic, alpha-1B-, receptor
chr20_-_3713509 1.752 CENPB
centromere protein B, 80kDa
chr9_+_138991835 1.747 PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr6_+_31838751 1.745 NM_001039651
C6orf26
chromosome 6 open reading frame 26
chr5_+_139719970 1.723 NM_031467
SLC4A9
solute carrier family 4, sodium bicarbonate cotransporter, member 9
chr17_-_45620911 1.720 COL1A1
collagen, type I, alpha 1
chr9_-_116920232 1.713 NM_002160
TNC
tenascin C
chr5_+_149717394 1.712 NM_000356
NM_001008657
NM_001135243
NM_001135244
NM_001135245
NM_001195141
TCOF1





Treacher Collins-Franceschetti syndrome 1





chr8_+_37672427 1.712 NM_025069
ZNF703
zinc finger protein 703
chr15_+_72397934 1.699 NM_182791
CCDC33
coiled-coil domain containing 33
chr10_+_112247614 1.699 NM_004419
DUSP5
dual specificity phosphatase 5
chr19_+_1236766 1.697 NM_001405
EFNA2
ephrin-A2
chr19_-_46504831 1.696


chr5_+_139040242 1.688 CXXC5
CXXC finger protein 5
chr9_+_136673534 1.681 COL5A1
collagen, type V, alpha 1
chr9_-_138387903 1.678 CARD9
caspase recruitment domain family, member 9
chr8_+_1940282 1.678 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr20_+_62266217 1.677 MYT1
myelin transcription factor 1
chr16_+_1299693 1.673 UBE2I
ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)
chr16_+_84204424 1.671 NM_014615
KIAA0182
KIAA0182
chr3_-_13359746 1.668 NUP210
nucleoporin 210kDa
chr10_-_103525646 1.664 NM_006119
NM_033163
NM_033164
NM_033165
FGF8



fibroblast growth factor 8 (androgen-induced)




Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.27 1.76e-15 GO:0007275 multicellular organismal development
1.27 7.22e-14 GO:0048856 anatomical structure development
1.29 1.22e-13 GO:0048731 system development
1.24 1.50e-13 GO:0032502 developmental process
1.30 1.19e-09 GO:0030154 cell differentiation
1.35 1.65e-09 GO:0009653 anatomical structure morphogenesis
1.12 4.98e-09 GO:0065007 biological regulation
1.28 5.20e-09 GO:0048869 cellular developmental process
1.24 1.25e-08 GO:0048518 positive regulation of biological process
1.34 2.45e-08 GO:0007399 nervous system development
1.19 5.14e-08 GO:0023052 signaling
1.35 1.78e-07 GO:0051239 regulation of multicellular organismal process
1.40 3.86e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.41 4.70e-07 GO:0022008 neurogenesis
1.27 5.71e-07 GO:0048513 organ development
1.11 5.77e-07 GO:0050789 regulation of biological process
1.11 1.19e-06 GO:0050794 regulation of cellular process
1.41 1.27e-06 GO:0048699 generation of neurons
1.27 1.83e-06 GO:0007166 cell surface receptor linked signaling pathway
1.22 3.21e-06 GO:0048522 positive regulation of cellular process
1.39 3.99e-06 GO:0050793 regulation of developmental process
1.24 6.34e-06 GO:0065008 regulation of biological quality
1.53 6.48e-06 GO:0000904 cell morphogenesis involved in differentiation
1.44 6.69e-06 GO:0030182 neuron differentiation
1.38 7.12e-06 GO:0048468 cell development
1.13 8.75e-06 GO:0032501 multicellular organismal process
1.18 1.22e-05 GO:0007165 signal transduction
1.41 1.91e-05 GO:2000026 regulation of multicellular organismal development
1.36 1.92e-05 GO:0042127 regulation of cell proliferation
1.54 2.68e-05 GO:0032583 regulation of gene-specific transcription
1.22 2.80e-05 GO:0048519 negative regulation of biological process
1.06 3.63e-05 GO:0009987 cellular process
1.45 3.95e-05 GO:0051172 negative regulation of nitrogen compound metabolic process
1.54 4.77e-05 GO:0007409 axonogenesis
1.45 5.14e-05 GO:0009887 organ morphogenesis
1.42 5.47e-05 GO:0010628 positive regulation of gene expression
1.98 6.42e-05 GO:0048705 skeletal system morphogenesis
1.44 6.91e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.24 7.69e-05 GO:0048583 regulation of response to stimulus
1.52 9.47e-05 GO:0048667 cell morphogenesis involved in neuron differentiation
1.46 9.52e-05 GO:0051253 negative regulation of RNA metabolic process
1.51 9.66e-05 GO:0048812 neuron projection morphogenesis
1.41 9.72e-05 GO:0045595 regulation of cell differentiation
1.22 1.31e-04 GO:0048523 negative regulation of cellular process
1.59 1.76e-04 GO:0007411 axon guidance
1.46 1.99e-04 GO:0008284 positive regulation of cell proliferation
1.43 2.05e-04 GO:0010629 negative regulation of gene expression
1.59 2.36e-04 GO:0001501 skeletal system development
1.33 2.76e-04 GO:0032879 regulation of localization
1.55 3.15e-04 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.45 3.17e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.24 3.79e-04 GO:0023051 regulation of signaling
1.26 4.55e-04 GO:0009966 regulation of signal transduction
1.46 5.77e-04 GO:0031175 neuron projection development
1.40 6.50e-04 GO:0032989 cellular component morphogenesis
1.46 7.44e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.41 9.07e-04 GO:0000902 cell morphogenesis
2.70 9.15e-04 GO:0060349 bone morphogenesis
1.38 9.99e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.35 1.27e-03 GO:0007267 cell-cell signaling
2.43 1.30e-03 GO:0060348 bone development
1.37 1.31e-03 GO:0009890 negative regulation of biosynthetic process
1.44 1.35e-03 GO:0048858 cell projection morphogenesis
1.55 1.46e-03 GO:0060284 regulation of cell development
1.17 2.40e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.43 2.45e-03 GO:0032990 cell part morphogenesis
1.32 2.53e-03 GO:0040011 locomotion
1.38 2.76e-03 GO:0048878 chemical homeostasis
1.42 2.83e-03 GO:0007417 central nervous system development
1.71 3.39e-03 GO:0003012 muscle system process
1.15 3.44e-03 GO:0016043 cellular component organization
1.29 3.78e-03 GO:0007154 cell communication
1.26 3.96e-03 GO:0009893 positive regulation of metabolic process
1.59 3.96e-03 GO:0045596 negative regulation of cell differentiation
1.16 4.24e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.39 4.38e-03 GO:0048666 neuron development
1.33 4.46e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.52 4.50e-03 GO:0051093 negative regulation of developmental process
1.33 5.13e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.97 5.17e-03 GO:0030278 regulation of ossification
1.31 5.91e-03 GO:0042592 homeostatic process
1.28 6.29e-03 GO:0010646 regulation of cell communication
1.37 6.52e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.41 6.68e-03 GO:0006935 chemotaxis
1.41 6.68e-03 GO:0042330 taxis
1.55 6.77e-03 GO:0040012 regulation of locomotion
1.39 7.20e-03 GO:0007186 G-protein coupled receptor protein signaling pathway
1.37 7.39e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.50 7.81e-03 GO:0044057 regulation of system process
1.35 8.06e-03 GO:0051254 positive regulation of RNA metabolic process
1.14 8.07e-03 GO:0080090 regulation of primary metabolic process
1.54 8.18e-03 GO:0051270 regulation of cellular component movement
1.26 9.16e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.28 9.46e-03 GO:0009605 response to external stimulus
1.83 9.46e-03 GO:0010959 regulation of metal ion transport
1.13 9.64e-03 GO:0019222 regulation of metabolic process
1.30 1.02e-02 GO:0009888 tissue development
1.33 1.08e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.14 1.13e-02 GO:0051179 localization
1.13 1.20e-02 GO:0031323 regulation of cellular metabolic process
1.34 1.38e-02 GO:0009790 embryo development
1.42 1.46e-02 GO:0051094 positive regulation of developmental process
1.35 1.48e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.78 1.59e-02 GO:0001503 ossification
1.15 1.63e-02 GO:0051234 establishment of localization
1.34 1.67e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.44 1.76e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.56 1.77e-02 GO:0003014 renal system process
1.16 1.84e-02 GO:0071842 cellular component organization at cellular level
1.47 2.15e-02 GO:0007389 pattern specification process
1.51 2.21e-02 GO:0030029 actin filament-based process
1.38 2.53e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.24 2.59e-02 GO:0031325 positive regulation of cellular metabolic process
1.17 2.64e-02 GO:0051252 regulation of RNA metabolic process
1.62 2.68e-02 GO:0007517 muscle organ development
2.00 2.74e-02 GO:0021953 central nervous system neuron differentiation
1.13 2.88e-02 GO:0071840 cellular component organization or biogenesis
1.52 3.04e-02 GO:0051960 regulation of nervous system development
1.52 3.04e-02 GO:0061061 muscle structure development
1.14 3.09e-02 GO:0006810 transport
1.37 3.32e-02 GO:0010647 positive regulation of cell communication
1.29 3.42e-02 GO:0009891 positive regulation of biosynthetic process
2.22 3.50e-02 GO:0045667 regulation of osteoblast differentiation
1.17 3.59e-02 GO:0042221 response to chemical stimulus
1.29 3.93e-02 GO:0055085 transmembrane transport
1.29 3.96e-02 GO:0048584 positive regulation of response to stimulus
1.44 4.01e-02 GO:0007420 brain development
1.38 4.01e-02 GO:0001775 cell activation
1.15 4.24e-02 GO:0010468 regulation of gene expression
1.36 4.85e-02 GO:0023056 positive regulation of signaling

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.23 1.27e-06 GO:0044459 plasma membrane part
2.08 8.18e-04 GO:0033267 axon part
1.11 4.64e-03 GO:0071944 cell periphery
1.11 6.04e-03 GO:0005886 plasma membrane
1.40 9.19e-03 GO:0043005 neuron projection
1.46 1.17e-02 GO:0015629 actin cytoskeleton
1.26 2.38e-02 GO:0005615 extracellular space
2.24 2.74e-02 GO:0044306 neuron projection terminus
2.24 3.89e-02 GO:0043679 axon terminus

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.48 2.81e-08 GO:0043565 sequence-specific DNA binding
1.37 6.44e-07 GO:0001071 nucleic acid binding transcription factor activity
1.37 6.44e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.34 3.78e-06 GO:0030528 transcription regulator activity
1.09 6.07e-05 GO:0005515 protein binding
1.25 1.75e-02 GO:0005102 receptor binding
1.33 3.42e-02 GO:0008092 cytoskeletal protein binding