Motif ID: MYOD1.p2

Z-value: 2.152


Transcription factors associated with MYOD1.p2:

Gene SymbolEntrez IDGene Name
MYOD1 4654 myogenic differentiation 1



Activity profile for motif MYOD1.p2.

activity profile for motif MYOD1.p2


Sorted Z-values histogram for motif MYOD1.p2

Sorted Z-values for motif MYOD1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYOD1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_21742727 6.775 GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr22_+_21742364 5.502 NM_002073
GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr22_+_20068039 3.854 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr11_-_2127368 3.850 NM_001007139
IGF2
insulin-like growth factor 2 (somatomedin A)
chr22_-_20235372 3.493 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr8_-_143692814 3.416 NM_015193
ARC
activity-regulated cytoskeleton-associated protein
chr22_+_19248810 3.102 MED15
mediator complex subunit 15
chr17_+_73676219 2.926 NM_004710
SYNGR2
synaptogyrin 2
chr16_+_84204424 2.923 NM_014615
KIAA0182
KIAA0182
chr11_+_1830763 2.851 NM_002339
LSP1
lymphocyte-specific protein 1
chr11_+_63864263 2.755 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr19_-_3928516 2.707 EEF2
eukaryotic translation elongation factor 2
chr1_-_2451543 2.622 NM_001010926
HES5
hairy and enhancer of split 5 (Drosophila)
chr7_+_150414704 2.534 NM_001042535
NM_031946
AGAP3

ArfGAP with GTPase domain, ankyrin repeat and PH domain 3

chrX_-_152365138 2.452 NM_080701
TREX2
three prime repair exonuclease 2
chr9_+_37640996 2.307 NM_014907
FRMPD1
FERM and PDZ domain containing 1
chr1_+_2149993 2.251 NM_003036
SKI
v-ski sarcoma viral oncogene homolog (avian)
chr3_+_128190070 2.213 NM_032242
PLXNA1
plexin A1
chr5_+_176170041 2.212 NM_133369
UNC5A
unc-5 homolog A (C. elegans)
chr20_+_29870836 2.196 NM_033118
MYLK2
myosin light chain kinase 2
chr22_+_21552897 2.189 LOC100290481
immunoglobulin lambda light chain-like
chr2_+_94900904 2.105 NM_144705
TEKT4
tektin 4
chr1_+_109827975 2.103 NM_153340
ATXN7L2
ataxin 7-like 2
chr3_+_141879555 2.062 NM_152616
TRIM42
tripartite motif containing 42
chr1_+_22176004 2.025 NM_007352
CELA3A
CELA3B
chymotrypsin-like elastase family, member 3A
chymotrypsin-like elastase family, member 3B
chr20_+_60744268 2.023 SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr1_+_22200735 2.014 NM_005747
CELA3A
chymotrypsin-like elastase family, member 3A
chr11_+_817584 1.987 NM_173584
EFCAB4A
EF-hand calcium binding domain 4A
chr20_+_60744231 1.974 NM_016354
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr16_+_1246273 1.959 NM_012217
TPSD1
tryptase delta 1
chr5_-_525916 1.941 LOC25845
hypothetical LOC25845
chr17_-_40839082 1.928 NM_001159330
ARHGAP27
Rho GTPase activating protein 27
chr1_-_1679940 1.891 NM_001198995
NADK
NAD kinase
chr6_-_39398293 1.876 NM_001135105
NM_001135106
NM_001135107
NM_032115
KCNK16



potassium channel, subfamily K, member 16



chr9_+_132961683 1.871 NM_001185095
NM_001185096
NM_031426
AIF1L


allograft inflammatory factor 1-like


chr15_+_72906003 1.855 NM_001030005
CPLX3
complexin 3
chr1_-_199613427 1.849 NM_000364
NM_001001430
NM_001001431
NM_001001432
TNNT2



troponin T type 2 (cardiac)



chr19_+_48912053 1.841 NM_019612
IRGC
immunity-related GTPase family, cinema
chr7_+_97679501 1.840 NM_177455
BHLHA15
basic helix-loop-helix family, member a15
chr1_+_110456584 1.833 NM_203412
UBL4B
ubiquitin-like 4B
chr11_+_119616112 1.833 NM_014352
POU2F3
POU class 2 homeobox 3
chr13_+_112681626 1.805 NM_024979
MCF2L
MCF.2 cell line derived transforming sequence-like
chr7_+_1546535 1.778 MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr16_+_29582069 1.764 NM_003123
SPN
sialophorin
chr7_+_149104063 1.763 NM_198455
SSPO
SCO-spondin homolog (Bos taurus)
chr9_+_132961723 1.762 AIF1L
allograft inflammatory factor 1-like
chr22_+_19601940 1.756 CRKL
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr2_-_128149800 1.715 LIMS2
LIM and senescent cell antigen-like domains 2
chr22_+_21340757 1.713


chr7_-_149101227 1.712 NM_207336
ZNF467
zinc finger protein 467
chr14_-_105163301 1.704 IGHG4
immunoglobulin heavy constant gamma 4 (G4m marker)
chr7_-_130891861 1.699 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr1_+_18680010 1.696 NM_152375
KLHDC7A
kelch domain containing 7A
chr10_+_80735881 1.695


chr9_+_137733851 1.681 NM_020822
KCNT1
potassium channel, subfamily T, member 1
chr3_+_50204026 1.655 NM_000172
NM_144499
GNAT1

guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1

chr17_-_23716391 1.632 NM_001080837
SEBOX
SEBOX homeobox
chr1_+_203278952 1.630 NM_005076
CNTN2
contactin 2 (axonal)
chr13_+_112789669 1.605 MCF2L
MCF.2 cell line derived transforming sequence-like
chr9_+_138677197 1.605 NM_201446
NM_016215
EGFL7

EGF-like-domain, multiple 7

chr11_-_66945190 1.601 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr20_-_62208627 1.595 NM_005286
NPBWR2
neuropeptides B/W receptor 2
chr16_+_29582065 1.584 SPN
sialophorin
chr1_+_24518398 1.582 NM_198173
NM_198174
GRHL3

grainyhead-like 3 (Drosophila)

chr22_+_21852911 1.574 BCR
breakpoint cluster region
chrX_+_110226030 1.574 NM_002578
PAK3
p21 protein (Cdc42/Rac)-activated kinase 3
chrX_+_151557292 1.561 NM_018558
GABRQ
gamma-aminobutyric acid (GABA) receptor, theta
chr12_-_50871953 1.560 NM_001081492
NM_182507
KRT80

keratin 80

chr22_-_20419975 1.558 NM_013313
YPEL1
yippee-like 1 (Drosophila)
chrX_+_67830204 1.544 NM_001142504
STARD8
StAR-related lipid transfer (START) domain containing 8
chrX_+_67830215 1.527 STARD8
StAR-related lipid transfer (START) domain containing 8
chr17_-_43390108 1.518 NM_024320
PRR15L
proline rich 15-like
chr7_-_100009205 1.509 NM_001168682
SAP25
sin3A-binding protein 25
chr1_+_24518501 1.487 NM_001195010
GRHL3
grainyhead-like 3 (Drosophila)
chr22_+_21484240 1.485


chr22_+_21359175 1.482 IGLV3-25
immunoglobulin lambda variable 3-25
chr22_+_21852743 1.478 BCR
breakpoint cluster region
chrX_+_150614385 1.474 NM_024082
PRRG3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr12_+_47658502 1.452 NM_005430
WNT1
wingless-type MMTV integration site family, member 1
chr1_+_1971762 1.449 NM_002744
PRKCZ
protein kinase C, zeta
chr1_+_22835684 1.448 NM_015991
C1QA
complement component 1, q subcomponent, A chain
chr6_+_39124534 1.444 NM_002062
GLP1R
glucagon-like peptide 1 receptor
chr22_+_18085990 1.439 SEPT5-GP1BB
SEPT5
SEPT5-GP1BB read-through transcript
septin 5
chr22_+_18085891 1.432 SEPT5
septin 5
chrX_+_152823722 1.430 NM_000054
NM_001146151
AVPR2

arginine vasopressin receptor 2

chr19_-_5735775 1.423 NM_001134316
PRR22
proline rich 22
chr1_-_199613406 1.416 TNNT2
troponin T type 2 (cardiac)
chr4_+_2031036 1.399 NM_178557
NAT8L
N-acetyltransferase 8-like (GCN5-related, putative)
chr8_+_143542378 1.399 NM_001702
BAI1
brain-specific angiogenesis inhibitor 1
chr11_+_46311314 1.394 NM_201532
DGKZ
diacylglycerol kinase, zeta
chr14_+_91858677 1.384 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr14_-_64359565 1.375 NM_000347
NM_001024858
SPTB

spectrin, beta, erythrocytic

chr17_+_30498948 1.372 NM_001033576
NM_173167
UNC45B

unc-45 homolog B (C. elegans)

chr4_+_3737872 1.367 ADRA2C
adrenergic, alpha-2C-, receptor
chr16_+_2138608 1.364 NM_014353
RAB26
RAB26, member RAS oncogene family
chr5_+_176786279 1.351 NM_001004105
NM_001004106
NM_002082
GRK6


G protein-coupled receptor kinase 6


chr11_+_1816808 1.343 NM_003282
TNNI2
troponin I type 2 (skeletal, fast)
chr21_+_44856423 1.343 NM_198695
KRTAP10-8
keratin associated protein 10-8
chrX_+_102356659 1.307 NM_001080425
NM_001127688
BEX4

brain expressed, X-linked 4

chr22_+_21870293 1.299


chr1_+_117950029 1.284 NM_017709
FAM46C
family with sequence similarity 46, member C
chr1_+_15145001 1.280 NM_001017999
KAZN
kazrin, periplakin interacting protein
chr22_+_20880112 1.276


chr3_+_185580554 1.258 NM_003741
CHRD
chordin
chr8_-_145088679 1.254 NM_201383
PLEC
plectin
chr7_+_106472243 1.242 NM_002736
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr1_+_23990228 1.239 NM_007260
LYPLA2
lysophospholipase II
chr16_-_87244896 1.237 NM_000101
CYBA
cytochrome b-245, alpha polypeptide
chr9_+_134927185 1.232 NM_001807
CEL
carboxyl ester lipase (bile salt-stimulated lipase)
chr1_-_1840564 1.227 NM_178545
TMEM52
transmembrane protein 52
chr22_+_21027538 1.227


chr22_+_21464980 1.220


chr1_-_226661089 1.217 NM_145214
TRIM11
tripartite motif containing 11
chr7_+_150321771 1.212 NM_001160109
NM_001160110
NM_001160111
NOS3


nitric oxide synthase 3 (endothelial cell)


chr1_-_39871226 1.211 HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr11_+_56984702 1.187 NM_178570
RTN4RL2
reticulon 4 receptor-like 2
chrX_-_152871351 1.187 HCFC1
host cell factor C1 (VP16-accessory protein)
chr9_+_94987032 1.184 NM_006648
WNK2
WNK lysine deficient protein kinase 2
chr17_-_76720342 1.184 AATK
apoptosis-associated tyrosine kinase
chrX_-_9693916 1.182 NM_000273
GPR143
G protein-coupled receptor 143
chr19_+_1033797 1.174 HMHA1
histocompatibility (minor) HA-1
chr16_+_29581783 1.171 NM_001030288
SPN
sialophorin
chr1_+_17719405 1.171 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr19_+_1033816 1.166 HMHA1
histocompatibility (minor) HA-1
chr22_+_19248733 1.165 MED15
mediator complex subunit 15
chr1_-_31117948 1.160 SDC3
syndecan 3
chr22_+_38213174 1.158 NM_001098270
MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr17_-_77634455 1.156 FASN
fatty acid synthase
chr17_-_77647505 1.151 FASN
fatty acid synthase
chr19_+_8384181 1.151 NM_001005415
NM_001005416
NM_016496
MARCH2


membrane-associated ring finger (C3HC4) 2


chr17_-_959007 1.145 NM_001092
ABR
active BCR-related gene
chr17_-_76064842 1.143 NM_002522
NPTX1
neuronal pentraxin I
chr4_+_3738093 1.141 NM_000683
ADRA2C
adrenergic, alpha-2C-, receptor
chr2_-_241484245 1.141 NM_001085437
C2orf54
chromosome 2 open reading frame 54
chr22_+_20880159 1.129 IGLV6-57
immunoglobulin lambda variable 6-57
chrX_+_152454773 1.127 NM_001001344
NM_021949
ATP2B3

ATPase, Ca++ transporting, plasma membrane 3

chr20_+_36988469 1.123 FAM83D
family with sequence similarity 83, member D
chr11_+_2422747 1.109 NM_000218
KCNQ1
potassium voltage-gated channel, KQT-like subfamily, member 1
chr17_+_35046843 1.108 NM_001165937
NM_001165938
NM_006804
STARD3


StAR-related lipid transfer (START) domain containing 3


chr5_+_139008091 1.104 CXXC5
CXXC finger protein 5
chr6_+_36346214 1.103 NM_001145717
PNPLA1
patatin-like phospholipase domain containing 1
chr1_-_109651140 1.103 NM_001010985
MYBPHL
myosin binding protein H-like
chr11_-_129803712 1.102 NM_007037
ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr1_+_231816540 1.101 KCNK1
potassium channel, subfamily K, member 1
chr5_+_169465478 1.097 NM_012188
NM_144769
FOXI1

forkhead box I1

chr22_-_19716837 1.082 NM_004173
SLC7A4
solute carrier family 7 (cationic amino acid transporter, y+ system), member 4
chr16_+_2195709 1.079 MLST8
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr11_-_129803515 1.069 ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr2_+_233099113 1.067 NM_000751
CHRND
cholinergic receptor, nicotinic, delta
chr1_-_37991160 1.065 EPHA10
EPH receptor A10
chr9_+_134843918 1.065 NM_001135031
NM_004188
GFI1B

growth factor independent 1B transcription repressor

chr17_+_71229151 1.060 ITGB4
integrin, beta 4
chr17_+_71229110 1.057 NM_000213
NM_001005731
ITGB4

integrin, beta 4

chr15_+_38843535 1.056 NM_005258
GCHFR
GTP cyclohydrolase I feedback regulator
chr1_+_53300410 1.055 NM_153703
PODN
podocan
chr20_-_60484420 1.054 NM_080473
GATA5
GATA binding protein 5
chr5_+_139008667 1.053 CXXC5
CXXC finger protein 5
chr1_+_109594163 1.052 NM_001408
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr19_+_10392128 1.051 NM_001111307
PDE4A
phosphodiesterase 4A, cAMP-specific
chr1_-_199608941 1.051 TNNT2
troponin T type 2 (cardiac)
chr1_-_43509187 1.050 EBNA1BP2
EBNA1 binding protein 2
chr20_-_61669550 1.048 NM_033405
PRIC285
peroxisomal proliferator-activated receptor A interacting complex 285
chr19_-_17217022 1.047 NM_005234
NR2F6
nuclear receptor subfamily 2, group F, member 6
chr1_+_12149637 1.036 NM_001066
TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
chr1_+_47375670 1.034 NM_001010969
CYP4A22
cytochrome P450, family 4, subfamily A, polypeptide 22
chr11_-_117203937 1.030 NM_021603
FXYD2
FXYD domain containing ion transport regulator 2
chr7_-_127833231 1.029 NM_001142573
NM_001142574
NM_001142575
IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chr16_+_2138688 1.029 RAB26
RAB26, member RAS oncogene family
chr5_+_173405343 1.028 HMP19
HMP19 protein
chr19_-_8118367 1.028 NM_032447
FBN3
fibrillin 3
chr11_+_73036241 1.027 NM_001130034
NM_001130035
PLEKHB1

pleckstrin homology domain containing, family B (evectins) member 1

chr9_+_91409746 1.025 NM_006705
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr1_+_35031185 1.015 NM_002060
GJA4
gap junction protein, alpha 4, 37kDa
chr7_+_2524022 1.015 NM_002304
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr4_+_39874921 1.011 NM_004310
RHOH
ras homolog gene family, member H
chrX_-_41667174 1.010 NM_001126054
NM_001126055
NM_003688
CASK


calcium/calmodulin-dependent serine protein kinase (MAGUK family)


chr3_+_39826032 1.008 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr16_+_4325142 0.998 GLIS2
GLIS family zinc finger 2
chr8_-_144969529 0.996 NM_015356
NM_182706
SCRIB

scribbled homolog (Drosophila)

chr1_-_2486313 0.995 NM_003820
TNFRSF14
tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
chr8_+_22465368 0.991 SORBS3
sorbin and SH3 domain containing 3
chr1_-_47428190 0.990 PDZK1IP1
PDZK1 interacting protein 1
chr8_+_22465171 0.989 NM_005775
SORBS3
sorbin and SH3 domain containing 3
chr6_-_34209250 0.987 NM_000841
GRM4
glutamate receptor, metabotropic 4
chr16_-_87460514 0.987 NM_001080487
PABPN1L
poly(A) binding protein, nuclear 1-like (cytoplasmic)
chr1_+_38032045 0.986 NM_001031740
NM_001113482
MANEAL

mannosidase, endo-alpha-like

chr8_-_41641881 0.983 NM_001142445
NM_020478
NM_020480
ANK1


ankyrin 1, erythrocytic


chr18_+_75724655 0.979 NM_012283
KCNG2
potassium voltage-gated channel, subfamily G, member 2
chr17_+_77289804 0.978 SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr17_+_70343659 0.977 TMEM104
transmembrane protein 104
chr1_+_12149662 0.976 TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
chrX_+_107174855 0.969 NM_001170553
NM_182607
VSIG1

V-set and immunoglobulin domain containing 1

chr7_+_2518688 0.967 NM_001166355
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chrX_+_117992623 0.966 NM_001031855
NM_024778
LONRF3

LON peptidase N-terminal domain and ring finger 3

chr5_+_176726918 0.966 RGS14
regulator of G-protein signaling 14
chr8_+_144171271 0.962 LY6E
lymphocyte antigen 6 complex, locus E
chr20_+_56848127 0.961 GNAS
GNAS complex locus
chr1_-_110108048 0.959 NM_024526
NM_133181
NM_139053
EPS8L3


EPS8-like 3


chr22_+_19660361 0.954 AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr7_+_97574054 0.951 NM_014916
LMTK2
lemur tyrosine kinase 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.21 6.02e-06 GO:0023052 signaling
1.19 1.26e-03 GO:0007165 signal transduction
1.37 1.94e-03 GO:0007154 cell communication
1.10 3.81e-03 GO:0065007 biological regulation
1.19 4.01e-03 GO:0048856 anatomical structure development
1.20 5.07e-03 GO:0048731 system development
1.10 9.62e-03 GO:0050789 regulation of biological process
1.67 1.07e-02 GO:0030029 actin filament-based process
1.10 1.62e-02 GO:0050794 regulation of cellular process
1.35 3.58e-02 GO:0006811 ion transport
1.67 4.21e-02 GO:0030036 actin cytoskeleton organization
1.38 4.24e-02 GO:0007267 cell-cell signaling
1.55 4.42e-02 GO:0051056 regulation of small GTPase mediated signal transduction
2.93 4.44e-02 GO:0003014 renal system process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.28 2.68e-06 GO:0044459 plasma membrane part
1.27 1.11e-02 GO:0031226 intrinsic to plasma membrane
1.27 1.50e-02 GO:0005887 integral to plasma membrane
1.13 1.83e-02 GO:0005886 plasma membrane
1.13 2.58e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.54 1.14e-04 GO:0008092 cytoskeletal protein binding
1.38 1.30e-03 GO:0022891 substrate-specific transmembrane transporter activity
1.36 1.66e-03 GO:0022857 transmembrane transporter activity
1.51 3.36e-03 GO:0030695 GTPase regulator activity
1.32 6.87e-03 GO:0022892 substrate-specific transporter activity
1.58 8.03e-03 GO:0003779 actin binding
1.47 1.23e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.35 2.47e-02 GO:0015075 ion transmembrane transporter activity
1.27 2.89e-02 GO:0005215 transporter activity
1.57 3.69e-02 GO:0005083 small GTPase regulator activity