Motif ID: MZF1.p2

Z-value: 2.380


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1



Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_138060 5.504 NM_018390
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr8_+_30361485 4.854 NM_001008710
NM_001008711
NM_001008712
NM_006867
RBPMS



RNA binding protein with multiple splicing



chr20_+_17498507 4.480 NM_001011546
NM_006870
DSTN

destrin (actin depolymerizing factor)

chr12_+_55808696 4.466 LRP1
low density lipoprotein receptor-related protein 1
chr16_-_3225360 4.363 NM_001145448
NM_198088
NM_001145446
NM_198087
ZNF200



zinc finger protein 200



chr6_+_7052985 4.174 NM_001003698
NM_001003699
NM_001003700
RREB1


ras responsive element binding protein 1


chr14_+_31615959 3.686 ARHGAP5
Rho GTPase activating protein 5
chr2_+_54536780 3.677 NM_003128
SPTBN1
spectrin, beta, non-erythrocytic 1
chr3_+_23219707 3.484 NM_152653
UBE2E2
ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)
chr6_+_7053183 3.453 RREB1
ras responsive element binding protein 1
chr10_+_114699953 3.430 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr2_+_115635982 3.399 NM_001178034
NM_001004360
DPP10

dipeptidyl-peptidase 10 (non-functional)

chr2_+_54537842 3.364 SPTBN1
spectrin, beta, non-erythrocytic 1
chr12_+_55808514 3.341 NM_002332
LRP1
low density lipoprotein receptor-related protein 1
chr14_+_59786047 3.326 PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr6_+_149680747 3.303 TAB2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr6_+_163755788 3.207 QKI
quaking homolog, KH domain RNA binding (mouse)
chr2_+_182464713 3.157 NM_001130445
NM_006751
SSFA2

sperm specific antigen 2

chr6_+_7052798 3.103 NM_001168344
RREB1
ras responsive element binding protein 1
chr9_+_33807168 3.076 NM_017811
UBE2R2
ubiquitin-conjugating enzyme E2R 2
chr2_+_36436316 3.013 CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr17_+_2443983 3.012 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr6_+_163755773 2.990 QKI
quaking homolog, KH domain RNA binding (mouse)
chr8_+_26204997 2.982 PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr2_-_161058550 2.897 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr2_+_182464910 2.886 SSFA2
sperm specific antigen 2
chr14_+_31615922 2.850 ARHGAP5
Rho GTPase activating protein 5
chr4_+_100135869 2.849 METAP1
methionyl aminopeptidase 1
chr14_+_31616196 2.842 NM_001030055
NM_001173
ARHGAP5

Rho GTPase activating protein 5

chr17_+_2443652 2.834 NM_000430
PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr9_+_33807213 2.832 UBE2R2
ubiquitin-conjugating enzyme E2R 2
chr7_+_104441730 2.832 NM_018682
NM_182931
MLL5

myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)

chr1_+_198975227 2.782 NM_203459
CAMSAP1L1
calmodulin regulated spectrin-associated protein 1-like 1
chr3_+_73128771 2.752 NM_174907
PPP4R2
protein phosphatase 4, regulatory subunit 2
chr2_+_46779553 2.745 NM_014011
SOCS5
suppressor of cytokine signaling 5
chr17_-_20886680 2.740 NM_015276
USP22
ubiquitin specific peptidase 22
chr1_+_26895108 2.738 NM_006015
NM_139135
ARID1A

AT rich interactive domain 1A (SWI-like)

chr20_+_30410447 2.656 ASXL1
additional sex combs like 1 (Drosophila)
chrX_+_154650590 2.649 NM_005840
SPRY3
sprouty homolog 3 (Drosophila)
chr1_+_61320213 2.636 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr10_+_22649977 2.632 NM_005180
BMI1
BMI1 polycomb ring finger oncogene
chr8_+_26204921 2.613 NM_002717
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr5_+_17270781 2.565 BASP1
brain abundant, membrane attached signal protein 1
chr4_-_1097313 2.535 NM_001131034
NM_001193318
NM_194439
RNF212


ring finger protein 212


chr14_+_59785703 2.529 NM_021003
NM_177951
PPM1A

protein phosphatase, Mg2+/Mn2+ dependent, 1A

chr5_+_17270474 2.527 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr7_-_104441679 2.491 LOC100216545
hypothetical LOC100216545
chr1_+_181259317 2.472


chr14_-_26136799 2.448 NM_002515
NM_006489
NM_006491
NOVA1


neuro-oncological ventral antigen 1


chr10_+_22650145 2.445 BMI1
BMI1 polycomb ring finger oncogene
chr2_+_36436873 2.422 NM_016441
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr6_+_163756187 2.406 QKI
quaking homolog, KH domain RNA binding (mouse)
chr17_+_24742068 2.380 NM_020791
TAOK1
TAO kinase 1
chr8_+_26204960 2.364 PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr3_+_73128667 2.291 PPP4R2
protein phosphatase 4, regulatory subunit 2
chr20_+_56900116 2.270 NM_001077488
GNAS
GNAS complex locus
chr14_+_59785739 2.263 PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr11_+_61352348 2.262 FADS2
fatty acid desaturase 2
chr5_+_92944680 2.225 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr2_+_149118791 2.208 EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr6_+_163755658 2.186 NM_006775
NM_206853
NM_206854
NM_206855
QKI



quaking homolog, KH domain RNA binding (mouse)



chr12_+_63958949 2.177 NM_001193461
MSRB3
methionine sulfoxide reductase B3
chr4_+_100135897 2.177 METAP1
methionyl aminopeptidase 1
chr20_-_48980858 2.168 NM_015339
NM_181442
ADNP

activity-dependent neuroprotector homeobox

chr10_+_28862068 2.168


chr1_+_88922424 2.154 NM_006256
PKN2
protein kinase N2
chr20_+_56899904 2.139 GNAS
GNAS complex locus
chr20_+_56899643 2.138 NM_001077489
NM_000516
NM_080426
GNAS


GNAS complex locus


chr1_+_117711575 2.134 NM_006699
MAN1A2
mannosidase, alpha, class 1A, member 2
chr2_+_137239583 2.124 THSD7B
thrombospondin, type I, domain containing 7B
chr10_+_89613399 2.122 PTEN
phosphatase and tensin homolog
chr5_+_92946348 2.112 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr1_-_154318412 2.109 NM_001093725
MEX3A
mex-3 homolog A (C. elegans)
chr1_-_146398501 2.100 LOC100286793
FLJ39739
hypothetical LOC100286793
hypothetical FLJ39739
chr16_+_68157370 2.078 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr11_+_61352209 2.071 NM_004265
FADS2
fatty acid desaturase 2
chr14_-_47213906 2.068 NM_001113498
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr12_+_19484387 2.065 AEBP2
AE binding protein 2
chr2_+_46779827 2.063 NM_144949
SOCS5
suppressor of cytokine signaling 5
chr13_+_19430906 2.052 NM_001190965
ZMYM2
zinc finger, MYM-type 2
chr12_+_19483578 2.051 NM_001114176
NM_153207
AEBP2

AE binding protein 2

chr10_+_28861705 2.048 WAC
WW domain containing adaptor with coiled-coil
chr14_+_59785723 2.042 PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr12_+_105873669 2.039 NM_152261
C12orf23
chromosome 12 open reading frame 23
chr15_+_36331411 2.037 SPRED1
sprouty-related, EVH1 domain containing 1
chr16_+_68157611 2.018 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr12_+_105873803 2.011 C12orf23
chromosome 12 open reading frame 23
chr10_+_89613071 2.005 NM_000314
PTEN
phosphatase and tensin homolog
chr20_+_8060762 1.995 NM_015192
NM_182734
PLCB1

phospholipase C, beta 1 (phosphoinositide-specific)

chr14_-_36059084 1.995 NM_001079668
NKX2-1
NK2 homeobox 1
chr10_+_28861730 1.993


chr21_+_39099624 1.982 ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr6_+_167970334 1.966 NM_001040000
MLLT4
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
chr10_+_28862514 1.926 WAC
WW domain containing adaptor with coiled-coil
chr5_+_10406829 1.920 MARCH6
membrane-associated ring finger (C3HC4) 6
chr21_+_39099717 1.918 NM_005239
ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr3_+_73128629 1.908 PPP4R2
protein phosphatase 4, regulatory subunit 2
chr4_-_46086528 1.903 NM_000807
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr6_+_96570565 1.883 NM_006581
FUT9
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr12_+_19484044 1.873 AEBP2
AE binding protein 2
chr3_+_182113125 1.866 FXR1
fragile X mental retardation, autosomal homolog 1
chr1_+_181708235 1.865 SMG7
Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr10_-_31647925 1.862 LOC220930
hypothetical LOC220930
chr1_+_181258952 1.847 NM_002293
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr2_+_241903943 1.839 NM_001008492
NM_004404
SEPT2

septin 2

chr6_+_157140733 1.838 NM_017519
NM_020732
ARID1B

AT rich interactive domain 1B (SWI1-like)

chr20_+_52525538 1.828 NM_018431
DOK5
docking protein 5
chr2_-_241903787 1.826 HDLBP
high density lipoprotein binding protein
chr2_-_241903657 1.822 HDLBP
high density lipoprotein binding protein
chr7_-_104441285 1.812 LOC100216545
hypothetical LOC100216545
chr13_+_34414390 1.809 NM_015678
NBEA
neurobeachin
chr12_+_44409743 1.797 ARID2
AT rich interactive domain 2 (ARID, RFX-like)
chr6_+_17501589 1.781 NM_006366
CAP2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr5_+_10406802 1.769 NM_005885
MARCH6
membrane-associated ring finger (C3HC4) 6
chrX_+_122923236 1.767 NM_001042750
NM_001042751
NM_006603
STAG2


stromal antigen 2


chr2_+_148495043 1.762 NM_018328
MBD5
methyl-CpG binding domain protein 5
chr9_+_130354490 1.754 NM_001130438
NM_001195532
NM_003127
SPTAN1


spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)


chr2_+_8739563 1.744 NM_002166
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr10_-_28861465 1.712 LOC220906
hypothetical LOC220906
chr17_+_52688842 1.704 NM_138962
MSI2
musashi homolog 2 (Drosophila)
chr9_+_108665168 1.703 NM_021224
ZNF462
zinc finger protein 462
chr10_+_28862429 1.691 NM_016628
NM_100486
WAC

WW domain containing adaptor with coiled-coil

chr3_+_182112748 1.679 NM_001013438
NM_001013439
NM_005087
FXR1


fragile X mental retardation, autosomal homolog 1


chr17_+_67628749 1.673 NM_000346
SOX9
SRY (sex determining region Y)-box 9
chr1_+_181708272 1.668 SMG7
Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr3_+_148610516 1.663 ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr10_+_31648103 1.648 NM_001174093
NM_001174095
NM_001174096
NM_030751
ZEB1



zinc finger E-box binding homeobox 1



chr9_-_43570725 1.646 NM_001145196
FAM75A6
family with sequence similarity 75, member A6
chr15_+_71131877 1.640 NM_001172623
NM_001172624
NM_002499
NEO1


neogenin 1


chr12_+_6907646 1.635 NM_001940
ATN1
atrophin 1
chr6_+_7053863 1.634 RREB1
ras responsive element binding protein 1
chr2_-_148495642 1.628 NM_181742
ORC4
origin recognition complex, subunit 4
chr4_+_81406765 1.628 NM_004464
NM_033143
FGF5

fibroblast growth factor 5

chr3_+_9414290 1.627 NM_001080517
SETD5
SET domain containing 5
chrX_-_1291526 1.622 NM_001012288
NM_022148
CRLF2

cytokine receptor-like factor 2

chr2_+_241904013 1.614 SEPT2
septin 2
chr12_+_970613 1.612 NM_178039
NM_178040
ERC1

ELKS/RAB6-interacting/CAST family member 1

chr12_+_109203412 1.609 NM_001135765
NM_001681
NM_170665
ATP2A2


ATPase, Ca++ transporting, cardiac muscle, slow twitch 2


chr22_+_44446341 1.605 NM_001167621
NM_013236
ATXN10

ataxin 10

chr17_+_57909979 1.593 NM_001112707
NM_006852
TLK2

tousled-like kinase 2

chr12_+_44409762 1.581 NM_152641
ARID2
AT rich interactive domain 2 (ARID, RFX-like)
chr19_+_59064795 1.579 MYADM
myeloid-associated differentiation marker
chr2_+_241904024 1.578 SEPT2
septin 2
chr2_+_209996913 1.574 NM_001039538
MAP2
microtubule-associated protein 2
chr10_+_89613347 1.552 PTEN
phosphatase and tensin homolog
chr4_+_100135810 1.551 NM_015143
METAP1
methionyl aminopeptidase 1
chr1_+_154318954 1.540 LMNA
lamin A/C
chr16_+_66676833 1.534 NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr2_-_241903925 1.533 NM_005336
HDLBP
high density lipoprotein binding protein
chr2_+_48610567 1.524 NM_001198593
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chr9_+_33015287 1.523 DNAJA1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr12_+_63958689 1.522 NM_001031679
NM_001193460
NM_198080
MSRB3


methionine sulfoxide reductase B3


chr5_+_10406980 1.498


chr3_+_180348818 1.497 NM_006218
PIK3CA
phosphoinositide-3-kinase, catalytic, alpha polypeptide
chr2_+_181553613 1.497 UBE2E3
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr2_-_161058120 1.482 RBMS1
RNA binding motif, single stranded interacting protein 1
chr6_+_157141565 1.482 ARID1B
AT rich interactive domain 1B (SWI1-like)
chr16_+_9093035 1.480 NM_014117
C16orf72
chromosome 16 open reading frame 72
chr1_+_93686154 1.472 NM_001024948
NM_001164473
NM_017737
FNBP1L


formin binding protein 1-like


chr2_+_181553783 1.468 UBE2E3
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr2_+_172658453 1.451 NM_001038493
NM_178120
DLX1

distal-less homeobox 1

chr12_+_74071145 1.450 NM_152436
GLIPR1L2
GLI pathogenesis-related 1 like 2
chr16_+_9093072 1.450 C16orf72
chromosome 16 open reading frame 72
chr10_+_171410 1.449 ZMYND11
zinc finger, MYND-type containing 11
chr5_+_65258139 1.449 NM_001006600
NM_018695
ERBB2IP

erbb2 interacting protein

chr2_+_181553333 1.439 NM_182678
NM_006357
UBE2E3

ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)

chr15_+_97010219 1.425 NM_000875
IGF1R
insulin-like growth factor 1 receptor
chr2_+_85051942 1.417 KCMF1
potassium channel modulatory factor 1
chr7_-_94123308 1.413 SGCE
sarcoglycan, epsilon
chr5_+_49998528 1.402 NM_001178056
NM_024615
PARP8

poly (ADP-ribose) polymerase family, member 8

chr9_+_5619326 1.400 NM_001135920
KIAA1432
KIAA1432
chr4_+_39376058 1.398 NM_001111112
NM_001111113
NM_005339
UBE2K


ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)


chr7_+_106596641 1.395 NM_012257
HBP1
HMG-box transcription factor 1
chr17_+_43082557 1.393 KPNB1
karyopherin (importin) beta 1
chr2_-_159021201 1.387 NM_001171637
NM_138803
CCDC148

coiled-coil domain containing 148

chr15_+_94677572 1.385 NM_001145157
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr9_-_5997891 1.384 NM_001017969
KIAA2026
KIAA2026
chr9_+_33015270 1.380 DNAJA1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr5_+_36912656 1.374 NIPBL
Nipped-B homolog (Drosophila)
chr8_-_141536992 1.369 TRAPPC9
trafficking protein particle complex 9
chr14_-_23117833 1.353 NM_001146028
NM_032452
JPH4

junctophilin 4

chr16_+_66676851 1.351 NM_004555
NM_173163
NM_173164
NM_173165
NFATC3



nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3



chr9_-_65249429 1.345 NM_015667
NM_001113541
FAM75A7
FAM75A5
family with sequence similarity 75, member A7
family with sequence similarity 75, member A5
chr5_-_10406690 1.339


chr17_+_42963737 1.338 NPEPPS
aminopeptidase puromycin sensitive
chr3_+_23219490 1.331 UBE2E2
ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)
chr5_-_81082699 1.330 NM_012446
SSBP2
single-stranded DNA binding protein 2
chr2_+_42649348 1.326 MTA3
metastasis associated 1 family, member 3
chr1_+_61319976 1.319 NM_001145512
NFIA
nuclear factor I/A
chr3_-_189354510 1.313 LOC339929
hypothetical LOC339929
chr3_+_9414533 1.307 SETD5
SET domain containing 5
chr7_+_24579239 1.301 NM_016447
MPP6
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr4_+_184257337 1.301 NM_024949
WWC2
WW and C2 domain containing 2
chr4_+_79916576 1.300 BMP2K
BMP2 inducible kinase
chr22_+_39818553 1.285 NM_001429
EP300
E1A binding protein p300
chr7_+_94123672 1.285 PEG10
paternally expressed 10
chr12_+_52132353 1.282 PCBP2
poly(rC) binding protein 2
chr2_+_149119029 1.281 NM_015630
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr5_+_49998677 1.273 PARP8
poly (ADP-ribose) polymerase family, member 8
chr6_+_126153693 1.272 NM_001122842
NM_181782
NCOA7

nuclear receptor coactivator 7


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.14 7.60e-20 GO:0050794 regulation of cellular process
1.13 2.11e-19 GO:0065007 biological regulation
1.13 2.56e-19 GO:0050789 regulation of biological process
1.08 4.97e-19 GO:0009987 cellular process
1.24 2.90e-14 GO:0048522 positive regulation of cellular process
1.23 4.58e-14 GO:0048518 positive regulation of biological process
1.18 1.11e-13 GO:0023052 signaling
1.31 1.97e-13 GO:0009653 anatomical structure morphogenesis
1.15 2.03e-13 GO:0043170 macromolecule metabolic process
1.43 3.53e-13 GO:0051128 regulation of cellular component organization
1.23 1.44e-12 GO:0048519 negative regulation of biological process
1.24 3.31e-12 GO:0048523 negative regulation of cellular process
1.15 1.44e-11 GO:0044260 cellular macromolecule metabolic process
1.17 2.88e-11 GO:0032502 developmental process
1.28 3.04e-11 GO:0023051 regulation of signaling
1.18 1.10e-10 GO:0048856 anatomical structure development
1.28 1.52e-10 GO:0007399 nervous system development
1.20 1.78e-10 GO:0048731 system development
1.17 1.96e-10 GO:0007275 multicellular organismal development
1.17 2.40e-10 GO:0007165 signal transduction
1.16 1.94e-09 GO:0031323 regulation of cellular metabolic process
1.28 2.33e-09 GO:0009966 regulation of signal transduction
1.11 2.55e-09 GO:0044238 primary metabolic process
1.17 3.78e-09 GO:0016043 cellular component organization
1.16 4.26e-09 GO:0071840 cellular component organization or biogenesis
1.69 4.32e-09 GO:0051129 negative regulation of cellular component organization
1.10 6.10e-09 GO:0008152 metabolic process
1.15 1.23e-08 GO:0019222 regulation of metabolic process
1.32 1.43e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.23 1.73e-08 GO:0006464 protein modification process
1.40 1.90e-08 GO:0007167 enzyme linked receptor protein signaling pathway
1.16 2.00e-08 GO:0080090 regulation of primary metabolic process
1.32 2.79e-08 GO:0009892 negative regulation of metabolic process
1.10 3.10e-08 GO:0044237 cellular metabolic process
1.18 4.25e-08 GO:0071842 cellular component organization at cellular level
1.16 6.62e-08 GO:0060255 regulation of macromolecule metabolic process
1.17 1.45e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.17 1.54e-07 GO:0019538 protein metabolic process
1.43 2.07e-07 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.20 2.41e-07 GO:0030154 cell differentiation
1.31 3.27e-07 GO:0022008 neurogenesis
1.31 4.38e-07 GO:0010605 negative regulation of macromolecule metabolic process
1.21 4.85e-07 GO:0043412 macromolecule modification
1.20 5.26e-07 GO:0048869 cellular developmental process
1.13 7.19e-07 GO:0051716 cellular response to stimulus
1.31 7.32e-07 GO:0031324 negative regulation of cellular metabolic process
1.42 8.43e-07 GO:0000904 cell morphogenesis involved in differentiation
1.26 9.87e-07 GO:0009893 positive regulation of metabolic process
1.37 1.13e-06 GO:0032989 cellular component morphogenesis
1.25 1.16e-06 GO:0051239 regulation of multicellular organismal process
1.17 1.17e-06 GO:0044267 cellular protein metabolic process
1.27 1.47e-06 GO:0010604 positive regulation of macromolecule metabolic process
1.48 1.71e-06 GO:0016568 chromatin modification
1.26 2.12e-06 GO:0031325 positive regulation of cellular metabolic process
1.17 2.32e-06 GO:0031326 regulation of cellular biosynthetic process
1.27 2.96e-06 GO:0010646 regulation of cell communication
1.35 3.32e-06 GO:0010628 positive regulation of gene expression
1.28 4.59e-06 GO:0032879 regulation of localization
1.36 5.72e-06 GO:0000902 cell morphogenesis
1.28 6.55e-06 GO:0006793 phosphorus metabolic process
1.28 6.55e-06 GO:0006796 phosphate metabolic process
1.30 7.27e-06 GO:0048699 generation of neurons
1.34 7.66e-06 GO:0051254 positive regulation of RNA metabolic process
1.16 9.10e-06 GO:0009889 regulation of biosynthetic process
1.28 1.53e-05 GO:0050793 regulation of developmental process
1.31 2.01e-05 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.30 2.24e-05 GO:0051173 positive regulation of nitrogen compound metabolic process
1.15 2.51e-05 GO:0051171 regulation of nitrogen compound metabolic process
1.19 2.88e-05 GO:0048583 regulation of response to stimulus
1.32 2.96e-05 GO:0009890 negative regulation of biosynthetic process
1.22 3.84e-05 GO:0035556 intracellular signal transduction
1.59 3.97e-05 GO:0044087 regulation of cellular component biogenesis
1.33 5.10e-05 GO:0045893 positive regulation of transcription, DNA-dependent
1.29 5.20e-05 GO:0031328 positive regulation of cellular biosynthetic process
1.15 6.25e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.32 7.35e-05 GO:0031327 negative regulation of cellular biosynthetic process
1.33 8.60e-05 GO:0009725 response to hormone stimulus
1.20 9.44e-05 GO:0006996 organelle organization
1.39 1.00e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.96 1.05e-04 GO:0010563 negative regulation of phosphorus metabolic process
1.96 1.05e-04 GO:0045936 negative regulation of phosphate metabolic process
1.33 1.07e-04 GO:0010629 negative regulation of gene expression
1.33 1.14e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.32 1.28e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
1.31 1.42e-04 GO:0045595 regulation of cell differentiation
1.29 1.43e-04 GO:2000026 regulation of multicellular organismal development
1.15 1.46e-04 GO:0010468 regulation of gene expression
1.41 1.56e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.27 1.91e-04 GO:0009891 positive regulation of biosynthetic process
1.36 2.16e-04 GO:0019226 transmission of nerve impulse
1.36 2.16e-04 GO:0035637 multicellular organismal signaling
1.18 2.34e-04 GO:0048513 organ development
1.15 3.30e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.46 3.70e-04 GO:0040012 regulation of locomotion
1.38 3.81e-04 GO:0007409 axonogenesis
1.49 3.91e-04 GO:0030334 regulation of cell migration
1.46 4.90e-04 GO:0051270 regulation of cellular component movement
1.37 4.96e-04 GO:0048812 neuron projection morphogenesis
1.28 5.25e-04 GO:0006468 protein phosphorylation
1.30 6.38e-04 GO:0009719 response to endogenous stimulus
1.33 7.13e-04 GO:0051253 negative regulation of RNA metabolic process
1.33 7.28e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.42 7.54e-04 GO:0033043 regulation of organelle organization
1.49 8.49e-04 GO:0032269 negative regulation of cellular protein metabolic process
1.47 9.42e-04 GO:2000145 regulation of cell motility
1.25 9.57e-04 GO:0048468 cell development
1.47 9.84e-04 GO:0051248 negative regulation of protein metabolic process
1.35 1.06e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.15 1.12e-03 GO:0051252 regulation of RNA metabolic process
1.25 1.12e-03 GO:0008219 cell death
1.67 1.25e-03 GO:0010639 negative regulation of organelle organization
1.34 1.28e-03 GO:0031175 neuron projection development
2.05 1.42e-03 GO:0001933 negative regulation of protein phosphorylation
1.14 1.53e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.90 1.55e-03 GO:0042326 negative regulation of phosphorylation
1.28 1.65e-03 GO:0030182 neuron differentiation
1.15 1.70e-03 GO:0065008 regulation of biological quality
1.23 1.88e-03 GO:0032268 regulation of cellular protein metabolic process
1.27 1.95e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.36 1.99e-03 GO:0009968 negative regulation of signal transduction
1.25 2.03e-03 GO:0016265 death
1.35 2.23e-03 GO:0007268 synaptic transmission
1.27 2.26e-03 GO:0006915 apoptosis
1.17 2.28e-03 GO:0007166 cell surface receptor linked signaling pathway
1.29 2.34e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.34 2.40e-03 GO:0072358 cardiovascular system development
1.34 2.40e-03 GO:0072359 circulatory system development
1.22 2.58e-03 GO:0051246 regulation of protein metabolic process
1.43 2.63e-03 GO:0001944 vasculature development
1.32 2.78e-03 GO:0048858 cell projection morphogenesis
1.44 2.87e-03 GO:0001568 blood vessel development
1.57 3.20e-03 GO:0031400 negative regulation of protein modification process
1.30 3.31e-03 GO:0048666 neuron development
1.41 3.65e-03 GO:0051130 positive regulation of cellular component organization
1.32 3.68e-03 GO:0032990 cell part morphogenesis
1.40 3.96e-03 GO:0060284 regulation of cell development
1.24 3.96e-03 GO:0006351 transcription, DNA-dependent
1.29 4.12e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.26 4.83e-03 GO:0012501 programmed cell death
1.32 5.84e-03 GO:0006325 chromatin organization
1.16 6.82e-03 GO:0016070 RNA metabolic process
1.13 7.12e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.24 7.41e-03 GO:0016310 phosphorylation
1.28 7.94e-03 GO:0009887 organ morphogenesis
1.32 8.05e-03 GO:0048646 anatomical structure formation involved in morphogenesis
1.38 9.41e-03 GO:0044057 regulation of system process
1.36 9.76e-03 GO:0030163 protein catabolic process
1.46 1.29e-02 GO:0048514 blood vessel morphogenesis
1.17 1.31e-02 GO:0065009 regulation of molecular function
1.32 2.02e-02 GO:0023057 negative regulation of signaling
1.49 2.28e-02 GO:0016569 covalent chromatin modification
1.31 2.43e-02 GO:0010648 negative regulation of cell communication
1.20 3.05e-02 GO:0010941 regulation of cell death
1.20 3.45e-02 GO:0043067 regulation of programmed cell death
1.20 3.46e-02 GO:0042981 regulation of apoptosis
1.23 3.58e-02 GO:0031399 regulation of protein modification process
1.72 3.61e-02 GO:0030178 negative regulation of Wnt receptor signaling pathway
1.13 3.62e-02 GO:0006355 regulation of transcription, DNA-dependent
1.11 3.67e-02 GO:0034641 cellular nitrogen compound metabolic process
1.82 3.74e-02 GO:0051494 negative regulation of cytoskeleton organization
1.48 3.84e-02 GO:0016570 histone modification
1.25 3.95e-02 GO:0030030 cell projection organization
1.34 4.21e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.28 4.36e-02 GO:0007417 central nervous system development
1.29 4.47e-02 GO:0048585 negative regulation of response to stimulus
1.26 4.50e-02 GO:0009057 macromolecule catabolic process
1.49 4.96e-02 GO:0051493 regulation of cytoskeleton organization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.12 1.47e-11 GO:0005634 nucleus
1.06 2.11e-11 GO:0005622 intracellular
1.06 1.14e-10 GO:0044424 intracellular part
1.21 5.84e-09 GO:0005829 cytosol
1.07 1.65e-08 GO:0043231 intracellular membrane-bounded organelle
1.08 2.03e-08 GO:0005737 cytoplasm
1.07 2.09e-08 GO:0043227 membrane-bounded organelle
1.07 2.95e-08 GO:0043226 organelle
1.07 4.12e-08 GO:0043229 intracellular organelle
1.21 7.10e-08 GO:0031981 nuclear lumen
1.17 2.23e-06 GO:0043233 organelle lumen
1.17 6.43e-06 GO:0044428 nuclear part
1.16 8.21e-06 GO:0070013 intracellular organelle lumen
1.16 1.13e-05 GO:0031974 membrane-enclosed lumen
1.39 2.76e-05 GO:0045202 synapse
1.39 4.34e-05 GO:0043005 neuron projection
2.21 5.62e-05 GO:0008287 protein serine/threonine phosphatase complex
1.55 1.42e-04 GO:0030424 axon
2.16 1.44e-04 GO:0044306 neuron projection terminus
1.20 1.88e-04 GO:0005654 nucleoplasm
2.12 6.73e-04 GO:0043679 axon terminus
1.28 9.07e-04 GO:0030054 cell junction
1.65 1.36e-03 GO:0030055 cell-substrate junction
1.43 2.37e-03 GO:0016323 basolateral plasma membrane
1.47 3.02e-03 GO:0030425 dendrite
1.65 3.33e-03 GO:0005925 focal adhesion
1.63 4.15e-03 GO:0005924 cell-substrate adherens junction
1.37 6.11e-03 GO:0044456 synapse part
2.31 6.46e-03 GO:0043195 terminal button
1.51 6.65e-03 GO:0005912 adherens junction
1.47 8.23e-03 GO:0043025 neuronal cell body
1.07 1.35e-02 GO:0044444 cytoplasmic part
1.45 1.71e-02 GO:0044297 cell body
1.44 2.01e-02 GO:0031252 cell leading edge
1.45 2.27e-02 GO:0070161 anchoring junction
1.73 2.38e-02 GO:0030427 site of polarized growth
1.61 3.40e-02 GO:0042470 melanosome
1.61 3.40e-02 GO:0048770 pigment granule
1.79 3.73e-02 GO:0034708 methyltransferase complex
1.79 3.73e-02 GO:0035097 histone methyltransferase complex
1.65 4.12e-02 GO:0033267 axon part
1.10 4.23e-02 GO:0043228 non-membrane-bounded organelle
1.10 4.23e-02 GO:0043232 intracellular non-membrane-bounded organelle
2.14 4.58e-02 GO:0005881 cytoplasmic microtubule
1.47 4.92e-02 GO:0000151 ubiquitin ligase complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.14 7.95e-25 GO:0005515 protein binding
1.07 1.65e-19 GO:0005488 binding
1.32 1.64e-06 GO:0019899 enzyme binding
1.32 4.32e-06 GO:0043565 sequence-specific DNA binding
1.25 2.57e-05 GO:0030528 transcription regulator activity
1.54 1.64e-04 GO:0010843 promoter binding
1.52 2.29e-04 GO:0000975 regulatory region DNA binding
1.52 2.29e-04 GO:0001067 regulatory region nucleic acid binding
1.52 2.29e-04 GO:0044212 transcription regulatory region DNA binding
1.42 5.86e-04 GO:0008134 transcription factor binding
1.34 6.10e-04 GO:0019904 protein domain specific binding
1.22 1.52e-03 GO:0001071 nucleic acid binding transcription factor activity
1.22 1.52e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.38 2.62e-03 GO:0016563 transcription activator activity
1.26 6.35e-03 GO:0004672 protein kinase activity
1.47 6.57e-03 GO:0003682 chromatin binding
1.09 1.15e-02 GO:0043169 cation binding
1.09 1.18e-02 GO:0043167 ion binding
1.23 1.25e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.97 1.35e-02 GO:0019888 protein phosphatase regulator activity
1.27 1.37e-02 GO:0008092 cytoskeletal protein binding
1.09 2.11e-02 GO:0046872 metal ion binding
1.34 2.26e-02 GO:0016564 transcription repressor activity
1.87 2.45e-02 GO:0019208 phosphatase regulator activity
1.21 3.12e-02 GO:0016301 kinase activity