Motif ID: NFIL3.p2

Z-value: 1.186


Transcription factors associated with NFIL3.p2:

Gene SymbolEntrez IDGene Name
NFIL3 4783 nuclear factor, interleukin 3 regulated



Activity profile for motif NFIL3.p2.

activity profile for motif NFIL3.p2


Sorted Z-values histogram for motif NFIL3.p2

Sorted Z-values for motif NFIL3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFIL3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_2030527 1.635 NM_080836
STK35
serine/threonine kinase 35
chr5_+_56507029 1.475 NM_001127235
GPBP1
GC-rich promoter binding protein 1
chr1_+_25629968 1.419 NM_018202
TMEM57
transmembrane protein 57
chr13_+_96672705 1.409 MBNL2
muscleblind-like 2 (Drosophila)
chr5_-_79982584 1.212 NM_001190470
MTRNR2L2
MT-RNR2-like 2
chr13_+_96726415 1.211 MBNL2
muscleblind-like 2 (Drosophila)
chr14_+_23633101 1.205 NM_001018073
NM_004563
PCK2

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

chr3_+_63928459 1.192 NM_001128149
ATXN7
ataxin 7
chr4_+_74488910 1.188 ALB
albumin
chr4_+_74488947 1.172 ALB
albumin
chr13_+_96672541 1.170 NM_144778
NM_207304
MBNL2

muscleblind-like 2 (Drosophila)

chr4_+_74488835 1.109 NM_000477
ALB
albumin
chr4_-_153493133 1.018 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr2_-_63518589 1.016 NM_001042692
WDPCP
WD repeat containing planar cell polarity effector
chr17_-_70901303 1.006 GRB2
growth factor receptor-bound protein 2
chr7_+_142723340 0.888 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr17_-_59204622 0.871 CCDC47
coiled-coil domain containing 47
chr13_-_32678142 0.866 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr22_+_39817733 0.837 EP300
E1A binding protein p300
chr15_-_53996597 0.834 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr2_+_148319033 0.830 NM_001616
ACVR2A
activin A receptor, type IIA
chr17_+_59205289 0.800 NM_007372
NM_203499
DDX42

DEAD (Asp-Glu-Ala-Asp) box polypeptide 42

chr8_+_70567634 0.784 SULF1
sulfatase 1
chr17_+_59205244 0.777


chr4_-_153820535 0.772 NM_152680
TMEM154
transmembrane protein 154
chr18_+_30875297 0.756 NM_014268
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr17_-_59204685 0.751 NM_020198
CCDC47
coiled-coil domain containing 47
chr22_-_34564611 0.741 RPL41P5
ribosomal protein L41 pseudogene 5
chr5_-_32424444 0.704 ZFR
zinc finger RNA binding protein
chr4_-_77147625 0.700 NM_002416
CXCL9
chemokine (C-X-C motif) ligand 9
chr11_-_10487212 0.671 NM_001190702
MTRNR2L8
MT-RNR2-like 8
chr11_+_9552809 0.657 NM_001143976
WEE1
WEE1 homolog (S. pombe)
chr9_+_71009746 0.648 NM_001170415
NM_001170416
TJP2

tight junction protein 2 (zona occludens 2)

chr8_+_70567581 0.648 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr5_-_32424352 0.630 ZFR
zinc finger RNA binding protein
chr17_-_36528113 0.624 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr9_+_27514311 0.622 NM_020124
IFNK
interferon, kappa
chr11_+_35596310 0.607 NM_014344
FJX1
four jointed box 1 (Drosophila)
chr2_-_213723298 0.603 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr1_-_177106702 0.596 NM_004673
ANGPTL1
angiopoietin-like 1
chr14_+_101345878 0.587 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr17_+_55269974 0.568


chr4_+_110574376 0.564 NM_001042734
NM_006323
SEC24B

SEC24 family, member B (S. cerevisiae)

chr17_-_36559579 0.564 NM_033188
KRTAP4-5
keratin associated protein 4-5
chr13_+_96797290 0.560


chr4_+_110574420 0.557 SEC24B
SEC24 family, member B (S. cerevisiae)
chr16_-_69876262 0.530 FTSJD1
FtsJ methyltransferase domain containing 1
chr6_-_2785682 0.513 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr8_-_86441115 0.500 NM_001164830
CA1
carbonic anhydrase I
chr4_-_110574363 0.490 1/2-SBSRNA4
lncRNA_BC009800
chr16_+_24648446 0.475 NM_014494
TNRC6A
trinucleotide repeat containing 6A
chr9_+_126460511 0.474


chr2_+_87536174 0.461 NCRNA00152
non-protein coding RNA 152
chr2_+_87536106 0.457 NCRNA00152
non-protein coding RNA 152
chr3_-_195670256 0.449 NM_024524
ATP13A3
ATPase type 13A3
chr17_-_39340414 0.447 MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr2_+_135392857 0.446 NM_001241
NM_058241
CCNT2

cyclin T2

chr3_+_23962518 0.439 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr3_+_187813538 0.434 NM_001622
AHSG
alpha-2-HS-glycoprotein
chr3_+_134976965 0.434 TF
transferrin
chr2_+_227900471 0.427 NM_020194
MFF
mitochondrial fission factor
chr21_+_17841297 0.417 CXADR
coxsackie virus and adenovirus receptor
chr2_-_21081694 0.414 APOB
apolipoprotein B (including Ag(x) antigen)
chr4_+_170817787 0.412 CLCN3
chloride channel 3
chr4_+_144477432 0.412 NM_002039
NM_207123
GAB1

GRB2-associated binding protein 1

chr14_+_19458580 0.411 NM_001005483
OR4K5
olfactory receptor, family 4, subfamily K, member 5
chr17_+_55098280 0.401 CLTC
clathrin, heavy chain (Hc)
chr15_+_91244422 0.396 NM_001042572
NM_001271
CHD2

chromodomain helicase DNA binding protein 2

chr2_+_135392879 0.392 CCNT2
cyclin T2
chr15_+_91244563 0.390 CHD2
chromodomain helicase DNA binding protein 2
chr7_+_89681069 0.383 NM_001040666
STEAP2
six transmembrane epithelial antigen of the prostate 2
chr1_+_210805319 0.381 NM_001030287
ATF3
activating transcription factor 3
chr6_-_136889302 0.380 MAP7
microtubule-associated protein 7
chr6_-_133076873 0.380 NM_004666
VNN1
vanin 1
chr1_+_65503011 0.380 NM_014787
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr3_+_42107711 0.371 NM_001042646
TRAK1
trafficking protein, kinesin binding 1
chr17_+_36493927 0.370 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr1_-_54183833 0.366 NM_016126
HSPB11
heat shock protein family B (small), member 11
chr14_+_95792299 0.356 NM_000710
BDKRB1
bradykinin receptor B1
chr12_+_110328126 0.355 NM_005475
SH2B3
SH2B adaptor protein 3
chr7_-_141048358 0.349 NM_001080392
KIAA1147
KIAA1147
chr16_+_7322751 0.349 NM_145891
NM_145892
NM_145893
RBFOX1


RNA binding protein, fox-1 homolog (C. elegans) 1


chr21_+_43963484 0.349 PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr5_-_94442941 0.345 MCTP1
multiple C2 domains, transmembrane 1
chr7_+_115650240 0.345 NM_152829
TES
testis derived transcript (3 LIM domains)
chr1_+_194887630 0.344 NM_000186
NM_001014975
CFH

complement factor H

chr21_+_43963439 0.341 PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr2_-_74606819 0.341 NM_133637
DQX1
DEAQ box RNA-dependent ATPase 1
chr14_-_19867372 0.333 NM_182852
NM_182851
CCNB1IP1

cyclin B1 interacting protein 1, E3 ubiquitin protein ligase

chr3_+_171167243 0.329 NM_003262
SEC62
SEC62 homolog (S. cerevisiae)
chr21_+_43963446 0.328 PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr2_+_101874765 0.326 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr20_+_33223434 0.324 NM_006404
PROCR
protein C receptor, endothelial
chr2_-_202811459 0.323 NM_001005781
NM_001005782
NM_003352
SUMO1


SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)


chr8_+_99145925 0.322 NM_001170806
NM_173549
C8orf47

chromosome 8 open reading frame 47

chr5_-_94443300 0.321 NM_001002796
MCTP1
multiple C2 domains, transmembrane 1
chr16_+_3447957 0.320 NM_001083600
NM_024845
NAT15

N-acetyltransferase 15 (GCN5-related, putative)

chr2_-_98646367 0.316 NM_001160154
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr12_-_44407756 0.308 LOC400027
hypothetical LOC400027
chr8_+_17440664 0.306 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr12_-_116283793 0.306 NM_000620
NOS1
nitric oxide synthase 1 (neuronal)
chr11_+_65023038 0.301 MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr6_+_158654890 0.299


chr9_+_110664366 0.297 NM_006687
ACTL7A
actin-like 7A
chr14_+_19285426 0.295 NM_172194
OR4Q3
olfactory receptor, family 4, subfamily Q, member 3
chr7_+_142692165 0.295 NM_153345
TMEM139
transmembrane protein 139
chr3_+_187813553 0.294 AHSG
alpha-2-HS-glycoprotein
chr7_-_111216180 0.284 DOCK4
dedicator of cytokinesis 4
chr2_+_64540843 0.281 HSPC159
galectin-related protein
chr1_-_180621272 0.280 GLUL
glutamate-ammonia ligase
chr17_+_36515166 0.279 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr20_-_48980858 0.277 NM_015339
NM_181442
ADNP

activity-dependent neuroprotector homeobox

chr2_-_31491102 0.277 NM_000379
XDH
xanthine dehydrogenase
chr10_+_4995453 0.276 NM_001353
AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr14_+_20226762 0.275 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr6_+_167445284 0.268 NM_004367
CCR6
chemokine (C-C motif) receptor 6
chr2_+_101874809 0.268 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr12_+_54080480 0.267 NM_001005518
OR6C65
olfactory receptor, family 6, subfamily C, member 65
chr16_+_68890559 0.263 NM_001014449
NM_001014451
NM_007242
DDX19B


DEAD (Asp-Glu-Ala-As) box polypeptide 19B


chr2_+_113542017 0.261 NM_173161
IL1F10
interleukin 1 family, member 10 (theta)
chr3_-_11598829 0.257 NM_001128220
VGLL4
vestigial like 4 (Drosophila)
chr7_+_28692122 0.257 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr6_+_158654464 0.256 TULP4
tubby like protein 4
chr2_-_31491057 0.256 XDH
xanthine dehydrogenase
chr9_-_122679387 0.253 NM_001009936
NM_015651
PHF19

PHD finger protein 19

chr11_+_68818175 0.250 NM_138768
MYEOV
myeloma overexpressed (in a subset of t(11;14) positive multiple myelomas)
chr7_+_134114701 0.247 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr10_+_4995597 0.246 AKR1C1
AKR1C3
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr12_-_69434650 0.245 PTPRR
protein tyrosine phosphatase, receptor type, R
chr6_-_28429950 0.242 NM_145909
ZNF323
zinc finger protein 323
chr1_-_220788048 0.241 NM_024746
HHIPL2
HHIP-like 2
chr6_+_144654565 0.239 NM_007124
UTRN
utrophin
chr16_-_30010705 0.239 NM_004608
TBX6
T-box 6
chr21_+_43963496 0.238 PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr2_-_133895795 0.236 NCKAP5
NCK-associated protein 5
chr13_+_110165329 0.235 NM_005537
ING1
inhibitor of growth family, member 1
chr2_-_224611568 0.234 NM_001136530
SERPINE2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr1_+_40612016 0.233 SMAP2
small ArfGAP2
chr1_+_151081953 0.233 NM_001128600
LCE6A
late cornified envelope 6A
chr2_-_174475528 0.232


chr1_-_201422450 0.231 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr5_+_86712376 0.230


chr14_-_93919305 0.229 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr8_-_110689396 0.228 SYBU
syntabulin (syntaxin-interacting)
chr4_-_153523113 0.228 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr1_+_40611955 0.224 NM_022733
SMAP2
small ArfGAP2
chr1_+_177261627 0.222 FAM20B
family with sequence similarity 20, member B
chr16_+_76613912 0.218 NM_005752
CLEC3A
C-type lectin domain family 3, member A
chr1_-_21373816 0.217 NM_001198803
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr12_-_7547552 0.217 NM_004244
NM_203416
CD163

CD163 molecule

chr6_-_134415311 0.216 NM_145176
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr9_-_122679283 0.215 PHF19
PHD finger protein 19
chr22_+_20252020 0.215 UBE2L3
ubiquitin-conjugating enzyme E2L 3
chr18_+_19826734 0.212 NM_153211
TTC39C
tetratricopeptide repeat domain 39C
chr2_+_132196533 0.212 NM_013310
C2orf27A
chromosome 2 open reading frame 27A
chr19_-_16145285 0.210 NM_054113
CIB3
calcium and integrin binding family member 3
chr1_-_201422490 0.209 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr1_-_201422436 0.207 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr16_+_80086454 0.205 NM_030629
CMIP
c-Maf-inducing protein
chr4_+_155703581 0.204 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr6_-_136888771 0.202 NM_001198608
NM_001198609
NM_001198611
MAP7


microtubule-associated protein 7


chr1_-_148080888 0.201 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr6_+_24511123 0.201 NM_020662
MRS2
MRS2 magnesium homeostasis factor homolog (S. cerevisiae)
chr6_+_126349327 0.199 TRMT11
tRNA methyltransferase 11 homolog (S. cerevisiae)
chr5_-_43593277 0.198 NM_183323
PAIP1
poly(A) binding protein interacting protein 1
chr10_+_4995685 0.194 AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chrX_+_38548394 0.190 MID1IP1
MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr21_+_37714470 0.190 NM_130438
NM_001396
DYRK1A

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

chr2_+_169637255 0.189 NM_001142270
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr6_+_134800533 0.186 LOC154092
hypothetical LOC154092
chr10_+_85994788 0.186 NM_001012720
NM_001012722
NM_002921
RGR


retinal G protein coupled receptor


chr15_+_79276273 0.181 NM_001172128
IL16
interleukin 16 (lymphocyte chemoattractant factor)
chr2_+_131578889 0.180 NM_001100623
NM_017958
PLEKHB2

pleckstrin homology domain containing, family B (evectins) member 2

chr13_-_19008884 0.177 NM_001141968
NM_130785
NM_199254
TPTE2


transmembrane phosphoinositide 3-phosphatase and tensin homolog 2


chrX_+_38548316 0.177 MID1IP1
MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr22_+_20252015 0.176 UBE2L3
ubiquitin-conjugating enzyme E2L 3
chr11_+_93394025 0.174 NM_001098672
HEPHL1
hephaestin-like 1
chr22_+_20252026 0.174 UBE2L3
ubiquitin-conjugating enzyme E2L 3
chr4_-_88669267 0.172 SPARCL1
SPARC-like 1 (hevin)
chr12_+_50633430 0.172 NM_020327
ACVR1B
activin A receptor, type IB
chr1_+_177261678 0.171 NM_014864
FAM20B
family with sequence similarity 20, member B
chr6_+_126349268 0.166 NM_001031712
TRMT11
tRNA methyltransferase 11 homolog (S. cerevisiae)
chr10_-_98280299 0.164 TM9SF3
transmembrane 9 superfamily member 3
chr6_+_37511383 0.164


chr13_-_37070862 0.163 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr3_+_187813405 0.162 AHSG
alpha-2-HS-glycoprotein
chrX_+_38548373 0.159 MID1IP1
MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr6_+_131936057 0.158 NM_000045
ARG1
arginase, liver
chr1_+_61697209 0.156 NFIA
nuclear factor I/A
chr2_-_127817143 0.155 NM_006609
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr17_-_64649608 0.155 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chrX_-_153428196 0.155 G6PD
glucose-6-phosphate dehydrogenase
chr15_-_63871492 0.154 DENND4A
DENN/MADD domain containing 4A
chr4_+_47403107 0.153


chr15_+_75500284 0.153 NM_018200
HMG20A
high-mobility group 20A
chr1_-_201422368 0.153 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr6_+_147568795 0.153 STXBP5
syntaxin binding protein 5 (tomosyn)
chr2_-_192420168 0.153 NM_004657
SDPR
serum deprivation response
chr1_+_176577228 0.153 NM_004841
RASAL2
RAS protein activator like 2
chr6_+_153060722 0.147 NM_025107
MYCT1
myc target 1

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
5.84 1.33e-02 GO:0031091 platelet alpha granule
5.70 4.52e-02 GO:0031983 vesicle lumen

Nothing significant found in function category.