Motif ID: NFKB1_REL_RELA.p2

Z-value: 2.462


Transcription factors associated with NFKB1_REL_RELA.p2:

Gene SymbolEntrez IDGene Name
NFKB1 4790 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
REL 5966 v-rel reticuloendotheliosis viral oncogene homolog (avian)
RELA 5970 v-rel reticuloendotheliosis viral oncogene homolog A (avian)



Activity profile for motif NFKB1_REL_RELA.p2.

activity profile for motif NFKB1_REL_RELA.p2


Sorted Z-values histogram for motif NFKB1_REL_RELA.p2

Sorted Z-values for motif NFKB1_REL_RELA.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFKB1_REL_RELA.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_45993338 2.487 NM_018896
NM_198376
NM_198377
NM_198378
NM_198379
NM_198380
NM_198382
NM_198383
NM_198384
NM_198385
NM_198386
NM_198387
NM_198388
NM_198396
NM_198397
CACNA1G














calcium channel, voltage-dependent, T type, alpha 1G subunit














chr15_+_65217412 2.125 NM_001145103
SMAD3
SMAD family member 3
chr9_+_126094388 1.702 NM_001166169
NEK6
NIMA (never in mitosis gene a)-related kinase 6
chr15_+_80434362 1.662 UBE2Q2P2
ubiquitin-conjugating enzyme E2Q family member 2 pseudogene 2
chr6_+_41622267 1.454 FOXP4
forkhead box P4
chr1_+_6767968 1.439 NM_001195563
NM_015215
CAMTA1

calmodulin binding transcription activator 1

chr3_+_38470782 1.399 NM_001106
ACVR2B
activin A receptor, type IIB
chr9_+_126094067 1.361 NM_001166170
NM_001166171
NEK6

NIMA (never in mitosis gene a)-related kinase 6

chr6_+_41622111 1.322 NM_001012426
NM_001012427
NM_138457
FOXP4


forkhead box P4


chr2_+_170363573 1.307 NM_003142
SSB
Sjogren syndrome antigen B (autoantigen La)
chr7_+_142723340 1.253 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr5_+_56505412 1.173 NM_022913
GPBP1
GC-rich promoter binding protein 1
chr5_+_10617431 1.166 NM_001164440
ANKRD33B
ankyrin repeat domain 33B
chr16_-_65516919 1.166 NM_001128850
NM_004165
RRAD

Ras-related associated with diabetes

chr6_+_87921980 1.147 NM_015021
ZNF292
zinc finger protein 292
chr3_-_50311666 1.140 NM_012191
NM_003549
NAT6
HYAL3
N-acetyltransferase 6 (GCN5-related)
hyaluronoglucosaminidase 3
chr3_-_50311262 1.116 NAT6
HYAL3
N-acetyltransferase 6 (GCN5-related)
hyaluronoglucosaminidase 3
chr5_+_56505608 1.090 GPBP1
GC-rich promoter binding protein 1
chr10_+_30763056 1.073 MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr11_+_101693403 1.015 NM_001165
NM_182962
BIRC3

baculoviral IAP repeat containing 3

chr20_+_44180296 0.997 NM_001250
NM_152854
CD40

CD40 molecule, TNF receptor superfamily member 5

chr1_+_25629968 0.994 NM_018202
TMEM57
transmembrane protein 57
chr17_-_6400470 0.990 NM_001165966
NM_031220
PITPNM3

PITPNM family member 3

chr7_+_1536847 0.989 NM_002360
MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr10_+_30762862 0.970 NM_005204
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr1_+_204484081 0.944 NM_001910
NM_148964
CTSE

cathepsin E

chr20_+_30410447 0.920 ASXL1
additional sex combs like 1 (Drosophila)
chr9_+_138677197 0.912 NM_201446
NM_016215
EGFL7

EGF-like-domain, multiple 7

chr17_-_37144408 0.904 NM_001079870
NM_001079871
NM_177977
HAP1


huntingtin-associated protein 1


chr2_+_237143118 0.890 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr1_-_21489235 0.862 NM_001113349
ECE1
endothelin converting enzyme 1
chr17_-_36346240 0.853 KRT23
keratin 23 (histone deacetylase inducible)
chr6_+_130381408 0.847 NM_001007102
NM_032438
L3MBTL3

l(3)mbt-like 3 (Drosophila)

chr20_+_34635362 0.842 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr12_-_52939636 0.828 NM_001127321
CBX5
chromobox homolog 5
chr9_+_38382700 0.827 NM_000692
ALDH1B1
aldehyde dehydrogenase 1 family, member B1
chr4_+_81325447 0.806 NM_020226
PRDM8
PR domain containing 8
chr20_+_30409649 0.790 NM_001164603
NM_015338
ASXL1

additional sex combs like 1 (Drosophila)

chr20_-_42249146 0.787 JPH2
junctophilin 2
chr3_-_48607596 0.780 NM_000094
COL7A1
collagen, type VII, alpha 1
chr1_-_24386324 0.772 NM_170743
NM_173064
NM_173065
IL28RA


interleukin 28 receptor, alpha (interferon, lambda receptor)


chr2_+_201755865 0.771 NM_001230
NM_032974
NM_032977
CASP10


caspase 10, apoptosis-related cysteine peptidase


chr17_+_52026058 0.766 NM_005450
NOG
noggin
chr10_+_104144218 0.760 NM_001077493
NM_001077494
NFKB2

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

chr2_+_238432925 0.757 NM_005855
RAMP1
receptor (G protein-coupled) activity modifying protein 1
chr1_+_200246312 0.748 NM_001114309
NM_004433
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr12_-_47651812 0.738 NM_003394
WNT10B
wingless-type MMTV integration site family, member 10B
chr1_+_200246370 0.736 ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr16_+_1696162 0.732 NM_001040439
NM_015133
MAPK8IP3

mitogen-activated protein kinase 8 interacting protein 3

chr11_-_117521344 0.725 NM_001142349
SCN4B
sodium channel, voltage-gated, type IV, beta
chr17_+_24944605 0.723 NM_152345
ANKRD13B
ankyrin repeat domain 13B
chr15_+_80741827 0.719 LOC80154
hypothetical LOC80154
chr11_+_1846478 0.719 NM_001013253
LSP1
lymphocyte-specific protein 1
chr1_+_26896519 0.718 ARID1A
AT rich interactive domain 1A (SWI-like)
chr16_+_27232770 0.713 IL4R
interleukin 4 receptor
chr4_-_77176163 0.712 NM_005409
CXCL11
chemokine (C-X-C motif) ligand 11
chr9_+_38382696 0.710 ALDH1B1
aldehyde dehydrogenase 1 family, member B1
chr1_+_9571518 0.708 NM_001010866
NM_001130924
TMEM201

transmembrane protein 201

chr12_-_52939584 0.699 NM_001127322
CBX5
chromobox homolog 5
chr1_-_207892420 0.698 NM_000228
LAMB3
laminin, beta 3
chr2_+_201756048 0.694 CASP10
caspase 10, apoptosis-related cysteine peptidase
chr6_+_149681128 0.693 NM_015093
TAB2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr12_-_50871953 0.691 NM_001081492
NM_182507
KRT80

keratin 80

chr9_+_116125123 0.687 NM_000607
ORM1
orosomucoid 1
chr15_+_80741876 0.684 LOC80154
hypothetical LOC80154
chr2_+_113709553 0.670 LOC654433
hypothetical LOC654433
chr17_+_77783432 0.667 NM_001042423
SLC16A3
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr11_+_122031549 0.653 NM_032873
UBASH3B
ubiquitin associated and SH3 domain containing B
chr18_+_22060383 0.642 NM_005640
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr6_+_32713160 0.633 NM_002122
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr2_+_68855436 0.628 NM_001166276
NM_014882
ARHGAP25

Rho GTPase activating protein 25

chr20_-_42249631 0.626 NM_020433
NM_175913
JPH2

junctophilin 2

chr16_+_27232745 0.620 NM_000418
NM_001008699
IL4R

interleukin 4 receptor

chr14_+_58725104 0.616 NM_014992
DAAM1
dishevelled associated activator of morphogenesis 1
chr19_+_44595589 0.610 NM_022835
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr12_-_28016182 0.603 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr22_+_18330049 0.601 NM_007310
COMT
catechol-O-methyltransferase
chr13_-_49597776 0.597 DLEU2
deleted in lymphocytic leukemia 2 (non-protein coding)
chr10_+_104145421 0.593 NM_002502
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr1_+_51968096 0.592 OSBPL9
oxysterol binding protein-like 9
chr20_+_44180355 0.589 CD40
CD40 molecule, TNF receptor superfamily member 5
chr4_-_77163609 0.585 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr16_-_55259405 0.573 NM_005950
MT1G
metallothionein 1G
chr8_+_38877909 0.569 NM_021623
PLEKHA2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr3_+_173240136 0.563 FNDC3B
fibronectin type III domain containing 3B
chr19_-_56214765 0.561 NM_145888
KLK10
kallikrein-related peptidase 10
chr14_+_23685935 0.547 RNF31
ring finger protein 31
chr16_+_10387412 0.547 ATF7IP2
activating transcription factor 7 interacting protein 2
chr19_-_8361552 0.545 LOC100507567
hypothetical LOC100507567
chr3_+_120495906 0.543 NM_020754
ARHGAP31
Rho GTPase activating protein 31
chr19_+_4198049 0.541 NM_018074
CCDC94
coiled-coil domain containing 94
chr16_+_1299693 0.541 UBE2I
ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)
chr10_+_111959978 0.540 NM_001008541
MXI1
MAX interactor 1
chr9_+_116131889 0.539 NM_000608
ORM2
orosomucoid 2
chr16_-_49205063 0.538


chr17_-_46692369 0.538 NM_017643
MBTD1
mbt domain containing 1
chr2_-_235070431 0.536 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr6_+_149680747 0.533 TAB2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr7_+_150442652 0.531 AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr4_-_119493322 0.530 NM_003619
PRSS12
protease, serine, 12 (neurotrypsin, motopsin)
chr14_+_35365266 0.530 NM_032352
BRMS1L
breast cancer metastasis-suppressor 1-like
chr1_+_51968046 0.520 NM_148904
NM_148905
NM_148907
OSBPL9


oxysterol binding protein-like 9


chr5_-_168660293 0.515 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr14_-_19090251 0.515 NM_001145442
POTEG
POTEM
POTE ankyrin domain family, member G
POTE ankyrin domain family, member M
chr7_-_104440707 0.512 LOC100216545
hypothetical LOC100216545
chr17_+_35751796 0.511 NM_001024809
RARA
retinoic acid receptor, alpha
chr15_+_38550451 0.508 NM_130468
CHST14
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr6_+_30018265 0.508 HLA-A
major histocompatibility complex, class I, A
chr3_+_120496180 0.507 ARHGAP31
Rho GTPase activating protein 31
chr1_+_201862845 0.505 ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr19_+_47056162 0.503 RPS19
ribosomal protein S19
chr16_+_84490267 0.502 NM_002163
IRF8
interferon regulatory factor 8
chr1_-_1667123 0.499 NM_182838
SLC35E2B
SLC35E2
solute carrier family 35, member E2B
solute carrier family 35, member E2
chr12_-_55790355 0.492 NM_001178079
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr19_+_54160468 0.490 FTL
ferritin, light polypeptide
chr12_-_55310261 0.488 BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chr7_-_99899829 0.488 NM_001004323
C7orf61
chromosome 7 open reading frame 61
chr6_+_43060304 0.484 PPP2R5D
protein phosphatase 2, regulatory subunit B', delta
chr16_-_21221872 0.483 NM_001014444
NM_001888
CRYM

crystallin, mu

chr17_+_3515217 0.477 RPL21
ribosomal protein L21
chr6_+_17708483 0.477 NM_016255
FAM8A1
family with sequence similarity 8, member A1
chr20_-_44746529 0.470 NM_001011554
NM_001193340
SLC13A3

solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3

chr19_+_50274309 0.467 NM_001007270
NM_001007269
NM_024707
GEMIN7


gem (nuclear organelle) associated protein 7


chr2_+_44249565 0.464 PPM1B
protein phosphatase, Mg2+/Mn2+ dependent, 1B
chr1_-_208046011 0.463 NM_006147
IRF6
interferon regulatory factor 6
chr1_+_144188375 0.463 NM_153713
LIX1L
Lix1 homolog (mouse)-like
chr11_-_56846246 0.463 TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr20_-_34635091 0.462


chr17_+_14145051 0.459 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr4_-_185632610 0.457 NM_002199
IRF2
interferon regulatory factor 2
chr15_+_41871768 0.457 NM_001018108
SERF2
small EDRK-rich factor 2
chr11_+_128266460 0.451 NM_000890
KCNJ5
potassium inwardly-rectifying channel, subfamily J, member 5
chr6_-_46728188 0.451 NM_016593
CYP39A1
cytochrome P450, family 39, subfamily A, polypeptide 1
chr15_+_94677572 0.450 NM_001145157
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr2_+_68815416 0.446 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr6_+_35290160 0.445 NM_152753
SCUBE3
signal peptide, CUB domain, EGF-like 3
chr6_+_44202628 0.445 TMEM63B
transmembrane protein 63B
chr6_-_33268177 0.445 NM_001163771
NM_080679
NM_080680
NM_080681
COL11A2



collagen, type XI, alpha 2



chr16_+_55224034 0.443 NM_176870
MT1M
metallothionein 1M
chr2_+_219453487 0.443 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr19_+_8361265 0.442 RAB11B
RAB11B, member RAS oncogene family
chr6_+_35289699 0.439 SCUBE3
signal peptide, CUB domain, EGF-like 3
chr16_-_62573 0.439 NM_022450
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr16_+_1668291 0.438 HN1L
hematological and neurological expressed 1-like
chr16_+_87232501 0.437 NM_013278
IL17C
interleukin 17C
chr17_+_45401560 0.436 NM_138281
DLX4
distal-less homeobox 4
chr1_-_41722883 0.435 NM_001956
EDN2
endothelin 2
chr12_+_68923477 0.434 CNOT2
CCR4-NOT transcription complex, subunit 2
chr2_+_233633348 0.434 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr1_+_165865953 0.433 NM_052862
RCSD1
RCSD domain containing 1
chr4_+_144477432 0.432 NM_002039
NM_207123
GAB1

GRB2-associated binding protein 1

chr21_+_36679533 0.429 NM_005441
CHAF1B
chromatin assembly factor 1, subunit B (p60)
chr11_-_128399218 0.429 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr1_+_17719405 0.429 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr11_+_35596310 0.428 NM_014344
FJX1
four jointed box 1 (Drosophila)
chr9_+_129900590 0.428 SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr3_+_49481083 0.427 NM_001177643
DAG1
dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr11_+_118259684 0.427 NM_001716
CXCR5
chemokine (C-X-C motif) receptor 5
chr3_+_53170254 0.427 NM_006254
NM_212539
PRKCD

protein kinase C, delta

chr6_+_43060240 0.427 PPP2R5D
protein phosphatase 2, regulatory subunit B', delta
chr16_+_1668284 0.426 HN1L
hematological and neurological expressed 1-like
chr2_+_233633279 0.425 NM_001017915
NM_005541
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chr16_-_84342129 0.424 NM_206967
C16orf74
chromosome 16 open reading frame 74
chr3_-_37192720 0.423 NM_001134369
NM_006309
NM_017724
LRRFIP2


leucine rich repeat (in FLII) interacting protein 2


chr10_+_114699953 0.423 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr16_+_87164158 0.422 NM_144604
ZC3H18
zinc finger CCCH-type containing 18
chr7_+_123272458 0.421 NM_012269
HYAL4
hyaluronoglucosaminidase 4
chr1_+_160306093 0.421 NM_001164757
NM_014697
NOS1AP

nitric oxide synthase 1 (neuronal) adaptor protein

chr7_+_138566770 0.420 NM_173569
UBN2
ubinuclein 2
chr4_-_77147625 0.419 NM_002416
CXCL9
chemokine (C-X-C motif) ligand 9
chr3_-_71625318 0.418 FOXP1
forkhead box P1
chr10_+_75427853 0.417 NM_003373
NM_014000
VCL

vinculin

chr12_-_51233001 0.416 NM_033448
KRT71
keratin 71
chr11_-_5227611 0.415 NM_000559
HBG1
HBG2
hemoglobin, gamma A
hemoglobin, gamma G
chr6_+_31476400 0.413


chr1_+_201862548 0.412 NM_001001396
NM_001684
ATP2B4

ATPase, Ca++ transporting, plasma membrane 4

chr10_-_33663305 0.412 NRP1
neuropilin 1
chr20_+_44070946 0.411 NM_004994
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr8_-_143864933 0.410 NM_003695
LY6D
lymphocyte antigen 6 complex, locus D
chr6_-_34209250 0.408 NM_000841
GRM4
glutamate receptor, metabotropic 4
chr15_+_41871809 0.408 SERF2-C15ORF63
SERF2
SERF2-C15orf63 read-through transcript
small EDRK-rich factor 2
chr1_-_153209625 0.408 NM_001130040
NM_183001
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chr19_+_54160369 0.408 NM_000146
FTL
ferritin, light polypeptide
chr17_+_45405128 0.408 NM_001934
DLX4
distal-less homeobox 4
chr19_+_38556414 0.408 NM_001806
CEBPG
CCAAT/enhancer binding protein (C/EBP), gamma
chr12_+_12761085 0.405 NM_004064
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr19_-_18910790 0.404 NM_001145724
HOMER3
homer homolog 3 (Drosophila)
chr6_+_44352443 0.402 TMEM151B
transmembrane protein 151B
chr9_+_35550424 0.402 RUSC2
RUN and SH3 domain containing 2
chr17_+_35728070 0.401 RARA
retinoic acid receptor, alpha
chr11_+_63864263 0.400 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr7_+_149696901 0.400 REPIN1
replication initiator 1
chr19_+_19357629 0.400 NM_017660
GATAD2A
GATA zinc finger domain containing 2A
chr1_+_45046740 0.399 NM_001136537
BTBD19
BTB (POZ) domain containing 19
chr1_+_100590595 0.399 NM_003672
NM_033312
NM_033313
CDC14A


CDC14 cell division cycle 14 homolog A (S. cerevisiae)


chr19_+_47056102 0.398 RPS19
ribosomal protein S19
chr6_+_31782618 0.398 NM_001003693
LY6G6F
lymphocyte antigen 6 complex, locus G6F
chr8_+_22479115 0.397 NM_001018003
SORBS3
sorbin and SH3 domain containing 3
chr17_+_35727998 0.397 NM_001145301
NM_001145302
RARA

retinoic acid receptor, alpha

chr9_+_139265533 0.397 NM_001004353
C9orf173
chromosome 9 open reading frame 173

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.12 1.95e-07 GO:0009987 cellular process
1.40 4.70e-06 GO:0048523 negative regulation of cellular process
1.87 6.02e-06 GO:0045892 negative regulation of transcription, DNA-dependent
1.37 8.55e-06 GO:0048519 negative regulation of biological process
1.77 9.96e-06 GO:0010558 negative regulation of macromolecule biosynthetic process
1.83 1.76e-05 GO:0051253 negative regulation of RNA metabolic process
1.18 1.89e-05 GO:0050794 regulation of cellular process
1.73 2.65e-05 GO:0031327 negative regulation of cellular biosynthetic process
1.77 2.70e-05 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.76 3.69e-05 GO:0051172 negative regulation of nitrogen compound metabolic process
1.71 4.39e-05 GO:0009890 negative regulation of biosynthetic process
1.95 5.86e-05 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.75 7.57e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.31 1.30e-04 GO:0048518 positive regulation of biological process
1.33 1.35e-04 GO:0048522 positive regulation of cellular process
1.73 1.54e-04 GO:0010629 negative regulation of gene expression
1.15 2.80e-04 GO:0050789 regulation of biological process
1.55 3.33e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.14 7.68e-04 GO:0065007 biological regulation
1.88 1.53e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.25 2.54e-03 GO:0060255 regulation of macromolecule metabolic process
1.19 2.72e-03 GO:0043170 macromolecule metabolic process
1.23 4.80e-03 GO:0031323 regulation of cellular metabolic process
1.44 6.65e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.33 7.73e-03 GO:0048583 regulation of response to stimulus
1.50 7.73e-03 GO:0031324 negative regulation of cellular metabolic process
1.42 7.91e-03 GO:0002376 immune system process
1.41 8.24e-03 GO:0009893 positive regulation of metabolic process
1.28 8.91e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.30 1.12e-02 GO:0006355 regulation of transcription, DNA-dependent
1.29 1.46e-02 GO:0051252 regulation of RNA metabolic process
1.42 1.48e-02 GO:0031325 positive regulation of cellular metabolic process
1.48 1.84e-02 GO:0009611 response to wounding
1.27 1.94e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.71 1.99e-02 GO:0032583 regulation of gene-specific transcription
1.47 2.34e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.51 3.11e-02 GO:0006955 immune response
1.25 3.47e-02 GO:0031326 regulation of cellular biosynthetic process
1.36 3.49e-02 GO:0009966 regulation of signal transduction
1.25 3.53e-02 GO:0009889 regulation of biosynthetic process
1.26 4.09e-02 GO:0010468 regulation of gene expression

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.62 6.92e-04 GO:0005924 cell-substrate adherens junction
2.65 8.07e-04 GO:0005925 focal adhesion
2.52 1.56e-03 GO:0030055 cell-substrate junction
2.22 3.25e-03 GO:0005912 adherens junction
1.29 5.15e-03 GO:0005829 cytosol
1.10 1.33e-02 GO:0005737 cytoplasm
1.07 1.67e-02 GO:0044424 intracellular part
1.07 2.11e-02 GO:0005622 intracellular
4.61 2.18e-02 GO:0031519 PcG protein complex
2.00 3.08e-02 GO:0070161 anchoring junction
1.83 3.70e-02 GO:0016323 basolateral plasma membrane
1.09 4.58e-02 GO:0043227 membrane-bounded organelle
1.14 4.62e-02 GO:0005634 nucleus
1.09 4.64e-02 GO:0043231 intracellular membrane-bounded organelle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.23 2.64e-13 GO:0005515 protein binding
1.09 5.49e-05 GO:0005488 binding
1.56 2.39e-03 GO:0043565 sequence-specific DNA binding
1.46 2.57e-03 GO:0001071 nucleic acid binding transcription factor activity
1.46 2.57e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.85 4.29e-03 GO:0008134 transcription factor binding
1.45 4.30e-02 GO:0019899 enzyme binding