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Motif ID: NKX3-2.p2

Z-value: 2.064

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_+_225973845	1.366	NM_020864	KIAA1486	KIAA1486
chr3_-_188936941	1.286	NM_001130845	BCL6	B-cell CLL/lymphoma 6
chr10_+_4995453	1.198	NM_001353	AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr2_-_162717159	1.196	NM_002054	GCG	glucagon
chr2_+_218790109	1.159	NM_152862	ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa
chr13_+_75232797	1.139	NM_015842	LMO7	LIM domain 7
chr2_+_218790159	1.126		ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa
chr2_-_109728958	1.084	NM_144710 NM_178584	SEPT10	septin 10
chr2_+_228386800	1.084	NM_001130046 NM_004591	CCL20	chemokine (C-C motif) ligand 20
chr8_+_32905027	1.080
chr14_+_30098079	1.056	NM_017769	G2E3	G2/M-phase specific E3 ubiquitin protein ligase
chr8_-_122722674	1.037	NM_005328	HAS2	hyaluronan synthase 2
chr6_+_117910472	1.022	NM_173674	DCBLD1	discoidin, CUB and LCCL domain containing 1
chr2_+_109729176	1.015	NM_023016	ANKRD57	ankyrin repeat domain 57
chr8_+_120289735	1.013	NM_052886	MAL2	mal, T-cell differentiation protein 2 (gene/pseudogene)
chr2_+_54638957	1.007	NM_178313	SPTBN1	spectrin, beta, non-erythrocytic 1
chr2_+_218790364	0.936	NM_005731	ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa
chr10_+_98582648	0.923	NM_032440	LCOR	ligand dependent nuclear receptor corepressor
chr14_-_22610610	0.910	NM_001164816 NM_001164817	ACIN1	apoptotic chromatin condensation inducer 1
chr13_+_25726755	0.910	NM_001260	CDK8	cyclin-dependent kinase 8
chr2_+_171280944	0.863		SP5	Sp5 transcription factor
chr20_+_56904042	0.858		GNAS	GNAS complex locus
chr1_-_7998265	0.843		ERRFI1	ERBB receptor feedback inhibitor 1
chr2_+_219141761	0.839	NM_005444	RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)
chr3_+_69216747	0.838	NM_006407	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5
chr17_-_7996409	0.830	NM_002616	PER1	period homolog 1 (Drosophila)
chr9_+_6318348	0.824	NM_001001874 NM_001001875 NM_033516	TPD52L3	tumor protein D52-like 3
chr14_-_22610572	0.807		ACIN1	apoptotic chromatin condensation inducer 1
chr16_+_55963899	0.802	NM_002996	CX3CL1	chemokine (C-X3-C motif) ligand 1
chr3_+_138159396	0.802	NM_144717	IL20RB	interleukin 20 receptor beta
chr2_-_37727472	0.780		CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3
chr3_-_192063158	0.778	NM_001146686	GEMC1	geminin coiled-coil domain-containing protein 1
chr16_+_55963883	0.774		CX3CL1	chemokine (C-X3-C motif) ligand 1
chr3_+_134978615	0.774		TF	transferrin
chr12_+_79995927	0.762	NM_024560	ACSS3	acyl-CoA synthetase short-chain family member 3
chr2_+_86521939	0.761		KDM3A	lysine (K)-specific demethylase 3A
chr2_+_201099093	0.756	NM_001160033 NM_001160046 NM_152524	SGOL2	shugoshin-like 2 (S. pombe)
chr2_+_17585462	0.749		VSNL1	visinin-like 1
chr16_-_80602546	0.746	NM_145168	SDR42E1	short chain dehydrogenase/reductase family 42E, member 1
chr2_+_28828332	0.746		PPP1CB	protein phosphatase 1, catalytic subunit, beta isozyme
chr6_+_131190237	0.741	NM_001195597	LOC285733	hypothetical LOC285733
chr2_+_86521999	0.736	NM_001146688	KDM3A	lysine (K)-specific demethylase 3A
chr2_+_207215386	0.736	NM_001102659	LOC200726	hCG1657980
chr17_+_64020120	0.725	NM_002734 NM_212472	PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr3_+_112273352	0.721		PVRL3	poliovirus receptor-related 3
chr14_+_38714111	0.708	NM_002687	PNN	pinin, desmosome associated protein
chr16_+_55523526	0.705		HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr17_+_64020155	0.703		PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr5_+_38882017	0.703		OSMR	oncostatin M receptor
chr2_-_148495642	0.696	NM_181742	ORC4	origin recognition complex, subunit 4
chr4_-_163304567	0.691	NM_001128427 NM_001128428 NM_020116	FSTL5	follistatin-like 5
chr5_+_96297101	0.687	NM_005575	LNPEP	leucyl/cystinyl aminopeptidase
chr17_+_64020159	0.683		PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr3_-_188935363	0.683	NM_001134738	BCL6	B-cell CLL/lymphoma 6
chr2_-_21079145	0.675		APOB	apolipoprotein B (including Ag(x) antigen)
chr21_-_26345294	0.668
chr9_+_89302239	0.662		DAPK1	death-associated protein kinase 1
chr8_+_123863169	0.661		ZHX2	zinc fingers and homeoboxes 2
chr10_-_98311813	0.660		TM9SF3	transmembrane 9 superfamily member 3
chr3_+_61522922	0.657		PTPRG	protein tyrosine phosphatase, receptor type, G
chr6_-_123999640	0.652	NM_006073	TRDN	triadin
chr2_-_74460933	0.647	NM_001135040 NM_001190837 NM_004082	DCTN1	dynactin 1
chr4_+_95592067	0.645		PDLIM5	PDZ and LIM domain 5
chr2_+_187163232	0.639		ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
chr2_+_37282516	0.639		LOC100505876	hypothetical LOC100505876
chr14_-_23878871	0.639	NM_006871	RIPK3	receptor-interacting serine-threonine kinase 3
chr20_+_61622985	0.635		PPDPF	pancreatic progenitor cell differentiation and proliferation factor homolog (zebrafish)
chr3_+_187813538	0.626	NM_001622	AHSG	alpha-2-HS-glycoprotein
chr14_-_24115268	0.624	NM_001911	CTSG	cathepsin G
chr22_+_27994216	0.624		EWSR1	Ewing sarcoma breakpoint region 1
chr14_+_34831294	0.623	NM_002791	PSMA6	proteasome (prosome, macropain) subunit, alpha type, 6
chr3_+_48482213	0.622	NM_016381 NM_033629	TREX1	three prime repair exonuclease 1
chr8_+_123863075	0.617	NM_014943	ZHX2	zinc fingers and homeoboxes 2
chr10_-_90702490	0.615	NM_001613	ACTA2	actin, alpha 2, smooth muscle, aorta
chr20_+_2309553	0.612	NM_198994	TGM6	transglutaminase 6
chr12_+_67426225	0.612		SLC35E3	solute carrier family 35, member E3
chr2_+_228064531	0.612		AGFG1	ArfGAP with FG repeats 1
chr10_+_123862430	0.609		TACC2	transforming, acidic coiled-coil containing protein 2
chr14_+_34831355	0.605		PSMA6	proteasome (prosome, macropain) subunit, alpha type, 6
chr1_+_35507197	0.599		ZMYM4	zinc finger, MYM-type 4
chr14_+_69303614	0.595		SRSF5	serine/arginine-rich splicing factor 5
chr7_+_94130752	0.591		PEG10	paternally expressed 10
chr16_+_31105579	0.588
chr2_+_196229715	0.588	NM_001127257	SLC39A10	solute carrier family 39 (zinc transporter), member 10
chr1_+_107485071	0.588		NTNG1	netrin G1
chr9_+_2612052	0.586		VLDLR	very low density lipoprotein receptor
chr4_+_95592030	0.583	NM_001011513 NM_001011515 NM_001011516 NM_006457	PDLIM5	PDZ and LIM domain 5
chr13_+_25726238	0.582		CDK8	cyclin-dependent kinase 8
chr14_+_69303563	0.580		SRSF5	serine/arginine-rich splicing factor 5
chr14_+_69303556	0.579		SRSF5	serine/arginine-rich splicing factor 5
chr2_-_191724169	0.579	NM_003151	STAT4	signal transducer and activator of transcription 4
chr5_+_72179749	0.576		TNPO1	transportin 1
chr20_+_45564063	0.575		NCOA3	nuclear receptor coactivator 3
chr14_+_69303615	0.575		SRSF5	serine/arginine-rich splicing factor 5
chr2_+_28828112	0.573	NM_206876 NM_002709	PPP1CB	protein phosphatase 1, catalytic subunit, beta isozyme
chr4_+_109761170	0.570	NM_000995 NM_033625	RPL34	ribosomal protein L34
chr3_+_187813405	0.569		AHSG	alpha-2-HS-glycoprotein
chr2_+_218790143	0.569		ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa
chr14_+_69303633	0.569		SRSF5	serine/arginine-rich splicing factor 5
chr14_+_23633101	0.564	NM_001018073 NM_004563	PCK2	phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr14_+_69303565	0.564	NM_001039465 NM_006925	SRSF5	serine/arginine-rich splicing factor 5
chr11_-_2113297	0.563		IGF2	insulin-like growth factor 2 (somatomedin A)
chr12_+_99391870	0.563		NR1H4	nuclear receptor subfamily 1, group H, member 4
chr5_+_146594718	0.563	NM_001112724 NM_145001	STK32A	serine/threonine kinase 32A
chr6_+_7052798	0.553	NM_001168344	RREB1	ras responsive element binding protein 1
chr6_+_160068598	0.552	NM_152857	WTAP	Wilms tumor 1 associated protein
chr3_+_120375053	0.548	NM_006952	UPK1B	uroplakin 1B
chr10_+_42953886	0.547	NM_018590	CSGALNACT2	chondroitin sulfate N-acetylgalactosaminyltransferase 2
chr14_+_61653827	0.546		FLJ43390	hypothetical LOC646113
chr13_+_40783340	0.545	NM_001110798 NM_024561 NM_018527	NAA16	N(alpha)-acetyltransferase 16, NatA auxiliary subunit
chr21_-_26294332	0.544		APP	amyloid beta (A4) precursor protein
chr5_+_56507029	0.542	NM_001127235	GPBP1	GC-rich promoter binding protein 1
chr7_+_77004686	0.539	NM_002835	PTPN12	protein tyrosine phosphatase, non-receptor type 12
chr16_-_69271428	0.538		MTSS1L	metastasis suppressor 1-like
chr2_-_109728693	0.537		SEPT10	septin 10
chr7_+_94130673	0.535		PEG10	paternally expressed 10
chr7_-_102000072	0.534		POLR2J2 POLR2J3	polymerase (RNA) II (DNA directed) polypeptide J2 polymerase (RNA) II (DNA directed) polypeptide J3
chr22_+_27993997	0.533	NM_001163285 NM_001163286 NM_001163287 NM_005243 NM_013986	EWSR1	Ewing sarcoma breakpoint region 1
chr14_-_23874083	0.531	NM_001198568 NM_001198592 NM_139247	ADCY4	adenylate cyclase 4
chr22_-_27993933	0.531		RHBDD3	rhomboid domain containing 3
chr3_+_187813553	0.530		AHSG	alpha-2-HS-glycoprotein
chr5_+_52812236	0.527	NM_006350 NM_013409	FST	follistatin
chr13_-_110066694	0.526
chr2_+_200879040	0.525	NM_001100422 NM_001100424 NM_001100423	SPATS2L	spermatogenesis associated, serine-rich 2-like
chr2_-_21084077	0.524		APOB	apolipoprotein B (including Ag(x) antigen)
chr3_+_50101428	0.523		RBM5	RNA binding motif protein 5
chr17_+_8279860	0.521	NM_001025579 NM_030808	NDEL1	nudE nuclear distribution gene E homolog (A. nidulans)-like 1
chr22_+_33983444	0.520	NM_001003681	HMGXB4	HMG box domain containing 4
chr15_+_65145248	0.520	NM_005902	SMAD3	SMAD family member 3
chr20_+_45564007	0.519	NM_001174087 NM_001174088 NM_006534 NM_181659	NCOA3	nuclear receptor coactivator 3
chr17_+_11864841	0.519	NM_003010	MAP2K4	mitogen-activated protein kinase kinase 4
chr16_-_45562840	0.518		DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2
chr11_+_34894688	0.516		PDHX	pyruvate dehydrogenase complex, component X
chr16_+_73739890	0.516	NM_153688	ZFP1	zinc finger protein 1 homolog (mouse)
chr14_+_54238581	0.509		SAMD4A	sterile alpha motif domain containing 4A
chr12_+_12857516	0.507	NM_016355 NM_201224	DDX47	DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chr20_-_1486303	0.505	NM_178460	SIRPD	signal-regulatory protein delta
chr15_+_65145215	0.505		SMAD3	SMAD family member 3
chr11_-_10630408	0.504	NM_001098579	MRVI1	murine retrovirus integration site 1 homolog
chr4_+_74520796	0.504	NM_001134	AFP	alpha-fetoprotein
chr10_+_5126589	0.501		AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr16_+_49139694	0.500	NM_033119	NKD1	naked cuticle homolog 1 (Drosophila)
chr17_+_43082273	0.500	NM_002265	KPNB1	karyopherin (importin) beta 1
chr14_-_23117614	0.498		JPH4	junctophilin 4
chr3_+_58452560	0.497	NM_001128214	KCTD6	potassium channel tetramerisation domain containing 6
chr3_+_48482625	0.497		TREX1	three prime repair exonuclease 1
chr2_-_197499584	0.497	NM_024989	PGAP1	post-GPI attachment to proteins 1
chr14_+_54104383	0.497	NM_001161576 NM_015589	SAMD4A	sterile alpha motif domain containing 4A
chr14_+_75687997	0.496	NM_017926 NM_017972	C14orf118	chromosome 14 open reading frame 118
chr8_-_125785611	0.494		MTSS1	metastasis suppressor 1
chr6_+_160068544	0.489		WTAP	Wilms tumor 1 associated protein
chr11_+_65023218	0.489
chr3_+_50101355	0.488	NM_005778	RBM5	RNA binding motif protein 5
chr14_+_52243645	0.486	NM_002806	PSMC6	proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr20_+_33750645	0.484	NM_080748	ROMO1	reactive oxygen species modulator 1
chr2_-_191723978	0.483		STAT4	signal transducer and activator of transcription 4
chr2_-_241903657	0.483		HDLBP	high density lipoprotein binding protein
chr2_-_238861830	0.483	NM_022817	PER2	period homolog 2 (Drosophila)
chr16_+_2746363	0.481
chr20_+_56903595	0.480		GNAS	GNAS complex locus
chr1_+_93070202	0.475		RPL5	ribosomal protein L5
chr14_+_22305570	0.475	NM_005015	OXA1L	oxidase (cytochrome c) assembly 1-like
chr6_-_128263868	0.475	NM_001010923 NM_001164685	THEMIS	thymocyte selection associated
chr12_+_68150332	0.474	NM_001042555 NM_006654	FRS2	fibroblast growth factor receptor substrate 2
chr1_-_94779727	0.473	NM_001178096 NM_001993	F3	coagulation factor III (thromboplastin, tissue factor)
chr2_+_148495043	0.473	NM_018328	MBD5	methyl-CpG binding domain protein 5
chr1_+_93070186	0.472		RPL5	ribosomal protein L5
chr1_-_31251315	0.472		PUM1	pumilio homolog 1 (Drosophila)
chr3_+_113180517	0.471	NM_018394	ABHD10	abhydrolase domain containing 10
chr20_+_52525538	0.471	NM_018431	DOK5	docking protein 5
chr13_+_96797290	0.470
chr3_-_79899748	0.470	NM_002941	ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr14_-_22515725	0.469		JUB	jub, ajuba homolog (Xenopus laevis)
chr5_+_38881716	0.468	NM_001168355	OSMR	oncostatin M receptor
chr12_-_42231990	0.468	NM_025003	ADAMTS20	ADAM metallopeptidase with thrombospondin type 1 motif, 20
chr16_+_18903009	0.468	NM_001160364	TMC7	transmembrane channel-like 7
chr2_-_241903787	0.467		HDLBP	high density lipoprotein binding protein
chr10_+_96152262	0.467		TBC1D12	TBC1 domain family, member 12
chr5_+_36912656	0.466		NIPBL	Nipped-B homolog (Drosophila)
chr7_+_29200636	0.466	NM_004067	CHN2	chimerin (chimaerin) 2
chr3_+_106568430	0.465		ALCAM	activated leukocyte cell adhesion molecule
chr20_+_32045541	0.465		RALY	RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))
chr14_+_75688025	0.465		C14orf118	chromosome 14 open reading frame 118
chr2_+_241903395	0.464	NM_001008491 NM_006155	SEPT2	septin 2
chr10_+_5126556	0.464	NM_003739	AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr1_+_93070120	0.462	NM_000969	RPL5	ribosomal protein L5
chr20_+_42273013	0.461		LOC100505783	hypothetical LOC100505783
chr2_-_241903925	0.457	NM_005336	HDLBP	high density lipoprotein binding protein
chr3_-_192531018	0.457	NM_198152	UTS2D	urotensin 2 domain containing
chr14_+_36200867	0.456		PAX9	paired box 9
chr2_+_241904024	0.456		SEPT2	septin 2
chr2_+_171493870	0.456	NM_015530	GORASP2	golgi reassembly stacking protein 2, 55kDa
chr14_-_49848538	0.455	NM_024884	L2HGDH	L-2-hydroxyglutarate dehydrogenase
chr20_+_32045347	0.455		RALY	RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))
chr5_-_38881636	0.454
chr2_+_186311599	0.453	NM_173651	FSIP2	fibrous sheath interacting protein 2
chr1_+_70459686	0.451		SRSF11	serine/arginine-rich splicing factor 11
chr6_+_110406890	0.450	NM_005284	GPR6	G protein-coupled receptor 6
chr5_+_38881719	0.450	NM_003999	OSMR	oncostatin M receptor
chr14_+_36200815	0.449		PAX9	paired box 9

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.48	6.77e-03	GO:0042060	wound healing
1.37	1.53e-02	GO:0016265	death
1.21	1.65e-02	GO:0048519	negative regulation of biological process
1.37	1.69e-02	GO:0008219	cell death
1.22	2.17e-02	GO:0048523	negative regulation of cellular process
1.32	2.72e-02	GO:0010646	regulation of cell communication
1.14	3.20e-02	GO:0044260	cellular macromolecule metabolic process
1.40	3.25e-02	GO:0006915	apoptosis
1.22	3.46e-02	GO:0048869	cellular developmental process
1.06	3.95e-02	GO:0009987	cellular process
1.35	4.12e-02	GO:0009611	response to wounding
1.39	4.95e-02	GO:0012501	programmed cell death

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.08	1.52e-06	GO:0044424	intracellular part
1.08	2.57e-06	GO:0005622	intracellular
1.10	6.09e-05	GO:0005737	cytoplasm
1.08	2.39e-03	GO:0043231	intracellular membrane-bounded organelle
1.07	3.11e-03	GO:0043226	organelle
1.08	3.18e-03	GO:0043227	membrane-bounded organelle
1.07	3.33e-03	GO:0043229	intracellular organelle
1.79	6.21e-03	GO:0031252	cell leading edge
2.26	2.92e-02	GO:0031256	leading edge membrane
1.03	2.97e-02	GO:0005623	cell
1.03	3.68e-02	GO:0044464	cell part
1.10	4.49e-02	GO:0044444	cytoplasmic part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.15	1.36e-09	GO:0005515	protein binding
1.07	2.20e-05	GO:0005488	binding