Motif ID: NR6A1.p2

Z-value: 0.802


Transcription factors associated with NR6A1.p2:

Gene SymbolEntrez IDGene Name
NR6A1 2649 nuclear receptor subfamily 6, group A, member 1



Activity profile for motif NR6A1.p2.

activity profile for motif NR6A1.p2


Sorted Z-values histogram for motif NR6A1.p2

Sorted Z-values for motif NR6A1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR6A1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_21559959 1.271 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr7_+_100037817 0.875 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chr12_+_107797985 0.777 NM_001917
DAO
D-amino-acid oxidase
chr1_+_174698929 0.642 NM_020318
NM_021936
PAPPA2

pappalysin 2

chrX_+_48505097 0.554 NM_001080489
GLOD5
glyoxalase domain containing 5
chr9_+_123083540 0.535 GSN
gelsolin
chr3_-_127719283 0.513 NM_001165974
NM_144639
UROC1

urocanase domain containing 1

chr3_+_46594079 0.506 NM_003212
TDGF1
teratocarcinoma-derived growth factor 1
chr7_-_149669622 0.470 NM_002889
RARRES2
retinoic acid receptor responder (tazarotene induced) 2
chr8_+_142501188 0.437 NM_007079
NM_032611
PTP4A3

protein tyrosine phosphatase type IVA, member 3

chr17_-_45280377 0.417 NM_001077503
NM_001077504
NM_001077505
NM_001077506
NM_170685
TAC4




tachykinin 4 (hemokinin)




chr9_-_38059207 0.347 NM_003028
SHB
Src homology 2 domain containing adaptor protein B
chr6_-_132952517 0.337 NM_003967
TAAR5
trace amine associated receptor 5
chr16_+_82540172 0.331 NM_013370
NM_182980
OSGIN1

oxidative stress induced growth inhibitor 1

chrX_-_138552517 0.328 NM_001171877
NM_001171878
NM_001171879
NM_005369
MCF2



MCF.2 cell line derived transforming sequence



chr16_+_716936 0.317 NM_207112
NM_032304
HAGHL

hydroxyacylglutathione hydrolase-like

chr17_-_26648375 0.313 NM_002544
OMG
oligodendrocyte myelin glycoprotein
chr1_-_16006779 0.311 NM_001089591
UQCRHL
ubiquinol-cytochrome c reductase hinge protein-like
chr1_+_196153122 0.291 NM_020204
LHX9
LIM homeobox 9
chr17_-_45619038 0.288 COL1A1
collagen, type I, alpha 1
chr5_+_63838183 0.286 NM_001029875
RGS7BP
regulator of G-protein signaling 7 binding protein
chr19_+_10057972 0.263 C19orf66
chromosome 19 open reading frame 66
chr2_-_128792515 0.253 NM_004807
HS6ST1
heparan sulfate 6-O-sulfotransferase 1
chr1_+_154386358 0.250 NM_001193301
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr1_-_209732881 0.245 NM_001164688
NM_183059
RD3

retinal degeneration 3

chr22_+_19649460 0.245 AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr15_+_87540238 0.240 ABHD2
abhydrolase domain containing 2
chr7_+_1543644 0.227 MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr21_-_44506526 0.227 NM_013369
NM_175867
DNMT3L

DNA (cytosine-5-)-methyltransferase 3-like

chr9_-_38059082 0.226 SHB
Src homology 2 domain containing adaptor protein B
chrX_+_17563333 0.219 NM_001136024
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr12_-_56422120 0.219 NM_014770
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr7_-_126670804 0.216 NM_000845
GRM8
glutamate receptor, metabotropic 8
chr14_-_106241445 0.208 IGHV4-31
IGHV1-69
IGHA1
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 1-69
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr1_+_36160375 0.205 EIF2C1
eukaryotic translation initiation factor 2C, 1
chr9_-_14303509 0.194 NFIB
nuclear factor I/B
chr22_+_21393107 0.188 IGLJ3
immunoglobulin lambda joining 3
chr11_-_5980953 0.187 NM_001005179
OR56A4
olfactory receptor, family 56, subfamily A, member 4
chrX_-_21686079 0.187 NM_014332
SMPX
small muscle protein, X-linked
chr1_+_33003847 0.181 KIAA1522
KIAA1522
chr1_+_144152864 0.179 TXNIP
thioredoxin interacting protein
chr3_-_140879463 0.178 NM_178177
NMNAT3
nicotinamide nucleotide adenylyltransferase 3
chr16_+_24765052 0.176 NM_052944
SLC5A11
solute carrier family 5 (sodium/glucose cotransporter), member 11
chr16_-_68317945 0.173 NM_000903
NM_001025433
NM_001025434
NQO1


NAD(P)H dehydrogenase, quinone 1


chr11_+_65945050 0.170 NM_178864
NPAS4
neuronal PAS domain protein 4
chr19_+_10058023 0.166 C19orf66
chromosome 19 open reading frame 66
chr1_-_156923111 0.163 NM_003126
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr6_+_155453114 0.162 NM_012454
TIAM2
T-cell lymphoma invasion and metastasis 2
chr9_-_14303899 0.162 NFIB
nuclear factor I/B
chr1_-_205290921 0.162 NM_018566
YOD1
YOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae)
chr21_+_41610530 0.161 NM_058186
NM_206964
FAM3B

family with sequence similarity 3, member B

chr1_+_113038202 0.157 MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr4_-_70661018 0.155 NM_014465
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr3_+_46386636 0.149 NM_000579
NM_001100168
CCR5

chemokine (C-C motif) receptor 5

chr11_+_36274300 0.145 NM_001160167
PRR5L
proline rich 5 like
chr15_-_38953628 0.141 NM_133639
RHOV
ras homolog gene family, member V
chr9_-_129719031 0.139 NM_175039
NM_175040
ST6GALNAC4

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4

chr11_+_125163215 0.138 NM_001129883
PATE3
prostate and testis expressed 3
chr4_+_41309482 0.134 LIMCH1
LIM and calponin homology domains 1
chr22_+_19649417 0.134 NM_001018060
NM_144704
AIFM3

apoptosis-inducing factor, mitochondrion-associated, 3

chr1_-_40009513 0.131 NM_022120
OXCT2
3-oxoacid CoA transferase 2
chr1_+_210805319 0.130 NM_001030287
ATF3
activating transcription factor 3
chr17_+_71586857 0.127 NM_180990
ZACN
zinc activated ligand-gated ion channel
chr3_+_187866464 0.127 NM_000412
HRG
histidine-rich glycoprotein
chr8_-_37576515 0.125 LOC157860
hypothetical protein LOC157860
chr9_-_14304036 0.121 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr19_-_6671585 0.121 NM_000064
C3
complement component 3
chr17_-_9870292 0.119 NM_001130831
GAS7
growth arrest-specific 7
chrX_-_104352005 0.119 NM_031274
TEX13A
testis expressed 13A
chr7_-_65084622 0.117 GUSB
glucuronidase, beta
chr3_-_52287297 0.116 WDR82
WD repeat domain 82
chr1_-_159369041 0.107 DEDD
death effector domain containing
chr1_+_9222489 0.107 H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr16_-_360509 0.105 NM_006428
MRPL28
mitochondrial ribosomal protein L28
chr5_+_175241449 0.104 CPLX2
complexin 2
chr1_+_117253882 0.101 NM_020440
PTGFRN
prostaglandin F2 receptor negative regulator
chr1_-_159369081 0.098 NM_001039711
NM_032998
DEDD

death effector domain containing

chr1_+_143920424 0.096 NM_203458
NOTCH2NL
notch 2 N-terminal like
chr1_+_224064365 0.095 NM_001136018
EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr9_-_14303943 0.092 NFIB
nuclear factor I/B
chr19_+_46390916 0.088 NM_030622
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr8_-_57521702 0.085 NM_001135690
PENK
proenkephalin
chr7_-_65084641 0.085 GUSB
glucuronidase, beta
chr15_+_75074793 0.085 PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr16_+_55553262 0.084 NM_000078
CETP
cholesteryl ester transfer protein, plasma
chr7_-_65084597 0.083 GUSB
glucuronidase, beta
chr22_+_49388427 0.083 NM_016431
MAPK8IP2
mitogen-activated protein kinase 8 interacting protein 2
chr1_-_158091296 0.083 C1orf204
chromosome 1 open reading frame 204
chr17_-_40339919 0.080 GFAP
glial fibrillary acidic protein
chr2_+_96672200 0.080 NM_001113382
FER1L5
fer-1-like 5 (C. elegans)
chr19_+_44838373 0.079 NM_001190441
LGALS16
beta-galactoside-binding lectin
chr17_+_75507750 0.078


chr21_+_32687282 0.077 C21orf119
chromosome 21 open reading frame 119
chr9_+_37475911 0.077 NM_022490
POLR1E
polymerase (RNA) I polypeptide E, 53kDa
chr17_-_24426752 0.076 NM_004740
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr14_-_105610144 0.076 IGHA1
IGHG1
IGHG3
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr19_-_47261761 0.074 NM_002088
GRIK5
glutamate receptor, ionotropic, kainate 5
chr11_+_111294868 0.071 C11orf52
chromosome 11 open reading frame 52
chr6_-_31007905 0.070 NM_205854
SFTA2
surfactant associated 2
chr11_-_73397929 0.069 NM_003356
NM_022803
UCP3

uncoupling protein 3 (mitochondrial, proton carrier)

chr1_+_33003814 0.068 NM_001198972
NM_001198973
KIAA1522

KIAA1522

chr14_-_105542441 0.067 IGLJ3
IGHA1
IGHG1
IGHM
immunoglobulin lambda joining 3
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr6_+_167504070 0.066 NM_001145121
TCP10L2
TCP10
t-complex 10-like 2 (mouse)
t-complex 10 homolog (mouse)
chr6_-_133076873 0.064 NM_004666
VNN1
vanin 1
chr17_+_72958330 0.064 SEPT9
septin 9
chr1_-_925332 0.063 NM_001142467
NM_021170
HES4

hairy and enhancer of split 4 (Drosophila)

chrX_-_44287032 0.061 NM_173794
FUNDC1
FUN14 domain containing 1
chr21_-_44926485 0.061 NM_181686
KRTAP12-1
keratin associated protein 12-1
chr22_-_22389436 0.059


chr11_-_64520964 0.058 NM_138456
BATF2
basic leucine zipper transcription factor, ATF-like 2
chr11_+_65140207 0.058 NM_032223
PCNXL3
pecanex-like 3 (Drosophila)
chr6_-_43592670 0.055 YIPF3
Yip1 domain family, member 3
chr8_-_53789544 0.054 NM_001083617
NM_014781
RB1CC1

RB1-inducible coiled-coil 1

chr10_-_126097444 0.053 OAT
ornithine aminotransferase
chr1_+_224064427 0.052 EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr1_+_19796119 0.050


chr10_-_126097483 0.050 NM_000274
NM_001171814
OAT

ornithine aminotransferase

chr10_+_124020810 0.049 NM_144587
BTBD16
BTB (POZ) domain containing 16
chr19_-_48401532 0.049 NM_002780
NM_213633
PSG4

pregnancy specific beta-1-glycoprotein 4

chr1_+_26376560 0.048 NM_006314
CNKSR1
connector enhancer of kinase suppressor of Ras 1
chr19_-_5797465 0.046 FUT3
fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
chr19_-_48133089 0.045 NM_002783
PSG7
pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)
chrX_+_69404879 0.045 NM_004312
ARR3
arrestin 3, retinal (X-arrestin)
chr22_-_22389502 0.044 LOC91316
glucuronidase, beta/immunoglobulin lambda-like polypeptide 1 pseudogene
chrX_+_8392870 0.044 NM_001001888
VCX3B
VCX3A
variable charge, X-linked 3B
variable charge, X-linked 3A
chr21_-_42789369 0.043 NM_080860
RSPH1
radial spoke head 1 homolog (Chlamydomonas)
chrX_-_152748526 0.043 PDZD4
PDZ domain containing 4
chr12_+_107480423 0.043 NM_014301
NM_213595
ISCU

iron-sulfur cluster scaffold homolog (E. coli)

chr1_-_159435440 0.043 NM_005099
ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif, 4
chr11_+_111294810 0.043 NM_080659
C11orf52
chromosome 11 open reading frame 52
chr16_-_3246587 0.042 NM_000243
NM_001198536
MEFV

Mediterranean fever

chr9_-_113401921 0.041 NM_001146108
NM_001146109
PTGR1

prostaglandin reductase 1

chr14_-_106240998 0.040 IGHV1-69
IGHG1
immunoglobulin heavy variable 1-69
immunoglobulin heavy constant gamma 1 (G1m marker)
chr4_+_41309668 0.039 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr22_-_22389524 0.039 LOC91316
glucuronidase, beta/immunoglobulin lambda-like polypeptide 1 pseudogene
chr14_-_105279582 0.036


chr5_-_42211112 0.036


chr2_-_25418249 0.036 NM_022552
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr9_+_74326536 0.034 NM_138691
TMC1
transmembrane channel-like 1
chr8_-_27906287 0.034 NM_173833
SCARA5
scavenger receptor class A, member 5 (putative)
chr3_+_14691609 0.033 NM_001184957
NM_001184958
NM_032137
C3orf20


chromosome 3 open reading frame 20


chr1_+_26376611 0.033 CNKSR1
connector enhancer of kinase suppressor of Ras 1
chr1_+_78284176 0.033 NM_017655
GIPC2
GIPC PDZ domain containing family, member 2
chr9_-_139101089 0.032 LOC100289341
similar to hCG2022304
chr19_+_47079089 0.031 NM_004706
NM_198977
ARHGEF1

Rho guanine nucleotide exchange factor (GEF) 1

chr11_+_66070949 0.030 NM_001104
ACTN3
actinin, alpha 3
chr11_+_111462821 0.030 SDHD
succinate dehydrogenase complex, subunit D, integral membrane protein
chr2_-_162638746 0.027 DPP4
dipeptidyl-peptidase 4
chr1_+_234372454 0.027 NM_003272
GPR137B
G protein-coupled receptor 137B
chr1_-_46541517 0.024 LRRC41
leucine rich repeat containing 41
chr3_-_38153467 0.024 ACAA1
acetyl-CoA acyltransferase 1
chr5_-_65053630 0.022 NM_019072
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr1_-_120413698 0.022 NOTCH2
notch 2
chr11_-_3818759 0.022 NM_001665
RHOG
ras homolog gene family, member G (rho G)
chr4_+_41309690 0.022 LIMCH1
LIM and calponin homology domains 1
chr6_-_25982418 0.020 NM_001098486
NM_006632
SLC17A3

solute carrier family 17 (sodium phosphate), member 3

chr12_+_119632213 0.020 NM_001080533
UNC119B
unc-119 homolog B (C. elegans)
chr11_-_7917642 0.020 NM_001003745
OR10A3
olfactory receptor, family 10, subfamily A, member 3
chr20_-_42457717 0.019


chr17_+_12633504 0.018 NM_014859
ARHGAP44
Rho GTPase activating protein 44
chr21_-_36836767 0.018 NM_001146078
CLDN14
claudin 14
chr12_+_54045161 0.018 NM_001005497
OR6C75
olfactory receptor, family 6, subfamily C, member 75
chr11_-_111462627 0.018 NM_012459
TIMM8B
translocase of inner mitochondrial membrane 8 homolog B (yeast)
chr14_-_105524207 0.017 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr19_-_48382398 0.017 NM_001130014
NM_002781
PSG5

pregnancy specific beta-1-glycoprotein 5

chr14_+_105278855 0.017 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr10_+_91488704 0.017 KIF20B
kinesin family member 20B
chr9_+_139101235 0.016 NM_016219
MAN1B1
mannosidase, alpha, class 1B, member 1
chr14_-_75517844 0.016 NM_003239
TGFB3
transforming growth factor, beta 3
chr2_-_31215074 0.016 NM_024572
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr19_-_54231884 0.016 NM_033377
CGB1
CGB2
chorionic gonadotropin, beta polypeptide 1
chorionic gonadotropin, beta polypeptide 2
chr16_+_31274030 0.015 ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr5_-_14064846 0.015 DNAH5
dynein, axonemal, heavy chain 5
chrX_+_102727068 0.014 NM_001006935
NM_001006937
NM_024863
TCEAL4


transcription elongation factor A (SII)-like 4


chr1_-_20707196 0.014 NM_024544
MUL1
mitochondrial E3 ubiquitin protein ligase 1
chr17_+_77289704 0.014 SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr1_-_29380945 0.014 SRSF4
serine/arginine-rich splicing factor 4
chr1_+_217413746 0.014 NM_138794
LYPLAL1
lysophospholipase-like 1
chr11_-_3818713 0.013 RHOG
ras homolog gene family, member G (rho G)
chr6_-_43592679 0.013 NM_015388
YIPF3
Yip1 domain family, member 3
chr6_-_43592481 0.013 YIPF3
Yip1 domain family, member 3
chr6_-_116706828 0.013 TSPYL1
TSPY-like 1
chr1_-_20707103 0.011 MUL1
mitochondrial E3 ubiquitin protein ligase 1
chr11_+_111462743 0.011 NM_003002
SDHD
succinate dehydrogenase complex, subunit D, integral membrane protein
chr13_+_22653059 0.011 NM_000231
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr6_-_119137923 0.011 NM_001178035
C6orf204
chromosome 6 open reading frame 204
chr9_-_134219950 0.011 SETX
senataxin
chr16_+_31274020 0.010 ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr2_-_130646415 0.010 SMPD4
sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
chr1_+_217413818 0.010 LYPLAL1
lysophospholipase-like 1
chr14_+_104462195 0.010 PLD4
phospholipase D family, member 4
chr20_-_29464301 0.009 NM_001171832
DEFB121
defensin, beta 121
chr1_+_151035850 0.009 NM_178352
LCE1D
late cornified envelope 1D
chr14_-_105523735 0.009 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr1_+_107484151 0.009 NM_001113226
NM_001113228
NM_014917
NTNG1


netrin G1


chr19_-_7604569 0.008 NM_174895
PCP2
Purkinje cell protein 2
chr3_+_39826032 0.008 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr14_-_57963620 0.008 TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr7_-_97439500 0.008 MGC72080
MGC72080 pseudogene
chr14_-_105804211 0.007 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.