Motif ID: PAX4.p2

Z-value: 1.227


Transcription factors associated with PAX4.p2:

Gene SymbolEntrez IDGene Name
PAX4 5078 paired box 4



Activity profile for motif PAX4.p2.

activity profile for motif PAX4.p2


Sorted Z-values histogram for motif PAX4.p2

Sorted Z-values for motif PAX4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_1830763 2.660 NM_002339
LSP1
lymphocyte-specific protein 1
chr1_+_101475149 2.417 S1PR1
sphingosine-1-phosphate receptor 1
chr6_+_32515596 2.120 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr4_+_39874921 1.781 NM_004310
RHOH
ras homolog gene family, member H
chr1_+_101474892 1.766 NM_001400
S1PR1
sphingosine-1-phosphate receptor 1
chr5_-_1050408 1.748 LOC100506688
hypothetical protein LOC100506688
chr1_-_30977931 1.662 LAPTM5
lysosomal protein transmembrane 5
chr19_-_59476734 1.587 NM_001080978
NM_005874
LILRB2

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2

chr9_+_130719034 1.426 LRRC8A
leucine rich repeat containing 8 family, member A
chr19_+_59833719 1.391 NM_001081638
NM_001081639
NM_001081637
LILRB1


leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1


chr6_-_2580296 1.257 NM_152554
C6orf195
chromosome 6 open reading frame 195
chr1_+_34098662 1.053 NM_145205
HMGB4
high-mobility group box 4
chr10_+_124204168 1.047 NM_001099667
ARMS2
age-related maculopathy susceptibility 2
chrX_+_79164397 1.007 NM_016954
TBX22
T-box 22
chr19_+_59796858 0.967 NM_006863
LILRA1
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
chr11_-_113971681 0.931 NM_001077639
NM_017678
FAM55D

family with sequence similarity 55, member D

chr21_-_32573195 0.922 NM_018944
MIS18A
MIS18 kinetochore protein homolog A (S. pombe)
chr19_-_50688310 0.888 NM_206901
RTN2
reticulon 2
chr2_+_223625105 0.882 NM_080671
KCNE4
potassium voltage-gated channel, Isk-related family, member 4
chr3_+_187866464 0.873 NM_000412
HRG
histidine-rich glycoprotein
chr11_-_113971607 0.862 FAM55D
family with sequence similarity 55, member D
chr6_+_111409933 0.855 NM_032194
RPF2
ribosome production factor 2 homolog (S. cerevisiae)
chr5_+_38481392 0.839 NM_182801
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr17_-_44154878 0.837 NM_032391
PRAC
prostate cancer susceptibility candidate
chr4_-_40211324 0.827 RBM47
RNA binding motif protein 47
chr7_+_72486044 0.820 NM_003508
FZD9
frizzled homolog 9 (Drosophila)
chr6_+_32713160 0.804 NM_002122
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr13_+_26896614 0.791 NM_002097
GTF3A
general transcription factor IIIA
chr1_+_205137410 0.785 NM_001185156
NM_001185157
NM_001185158
NM_006850
IL24



interleukin 24



chr4_+_38860418 0.781 NM_025132
WDR19
WD repeat domain 19
chrX_+_71280758 0.769 NM_207422
FLJ44635
TPT1-like protein
chrX_+_150653873 0.766 NM_005140
CNGA2
cyclic nucleotide gated channel alpha 2
chr1_+_15655809 0.766 NM_033440
CELA2A
chymotrypsin-like elastase family, member 2A
chr11_+_72653197 0.744 NM_176796
NM_176797
P2RY6

pyrimidinergic receptor P2Y, G-protein coupled, 6

chr7_+_133462591 0.743 NM_144648
LRGUK
leucine-rich repeats and guanylate kinase domain containing
chrX_-_19598912 0.737 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chrX_-_107569256 0.731 NM_001847
COL4A6
collagen, type IV, alpha 6
chr4_-_40212670 0.727 NM_019027
RBM47
RNA binding motif protein 47
chr8_+_145718702 0.726


chr12_-_93568336 0.725 NM_020698
TMCC3
transmembrane and coiled-coil domain family 3
chr1_+_144236346 0.721 NM_003637
ITGA10
integrin, alpha 10
chr19_-_18749728 0.718


chr19_-_6284561 0.704 NM_133492
ACER1
alkaline ceramidase 1
chr9_-_122716670 0.696 NM_001190947
TRAF1
TNF receptor-associated factor 1
chrX_-_47941142 0.692 NM_021015
NM_175723
SSX5

synovial sarcoma, X breakpoint 5

chr1_+_144236398 0.681 ITGA10
integrin, alpha 10
chr7_+_133884388 0.674 NM_001080538
AKR1B15
aldo-keto reductase family 1, member B15
chr1_-_160613203 0.671 NM_182581
C1orf111
chromosome 1 open reading frame 111
chrX_+_154880439 0.670 NM_002186
IL9R
interleukin 9 receptor
chr5_+_176744037 0.665 NM_001167579
NM_003052
SLC34A1

solute carrier family 34 (sodium phosphate), member 1

chr7_+_68702516 0.661 AUTS2
autism susceptibility candidate 2
chr4_+_71418886 0.658 NM_212557
AMTN
amelotin
chr6_+_30002084 0.657


chrX_+_102498035 0.620 NM_001006612
NM_001006613
NM_001006614
NM_016303
WBP5



WW domain binding protein 5



chr9_+_91409746 0.615 NM_006705
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr17_+_7125702 0.600 NM_001042
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
chr22_+_35777561 0.597 NM_024681
KCTD17
potassium channel tetramerisation domain containing 17
chr19_+_2928480 0.591 NM_001143986
NM_024760
TLE6

transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)

chr7_-_96492064 0.586 NM_005221
DLX5
distal-less homeobox 5
chrX_-_138875342 0.578 NM_001013403
CXorf66
chromosome X open reading frame 66
chrX_+_65300803 0.570 NM_001130860
NM_014799
HEPH

hephaestin

chrX_+_52528485 0.567 NM_001097597
NM_001097598
NM_001097604
NM_001097605
NM_001097592
NM_001097593
NM_001097594
NM_001097596
NM_020411
NM_133430
XAGE1C

XAGE1E

XAGE1A

XAGE1B

XAGE1D

X antigen family, member 1C

X antigen family, member 1E

X antigen family, member 1A

X antigen family, member 1B

X antigen family, member 1D

chr7_-_139744725 0.565 NM_032295
NM_207113
SLC37A3

solute carrier family 37 (glycerol-3-phosphate transporter), member 3

chr11_+_10439253 0.554 NM_001172430
AMPD3
adenosine monophosphate deaminase 3
chr12_+_52653176 0.552 NM_014212
HOXC11
homeobox C11
chr4_+_113958652 0.552 NM_001127493
ANK2
ankyrin 2, neuronal
chr5_-_58918031 0.550 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_+_151147646 0.549 NM_005547
IVL
involucrin
chr7_-_135263737 0.544 MTPN
LUZP6
myotrophin
leucine zipper protein 6
chr16_+_29739215 0.541 NM_005115
NM_017458
MVP

major vault protein

chrX_+_7770302 0.541 NM_013452
VCX
variable charge, X-linked
chr15_+_79213660 0.541 NM_173528
C15orf26
chromosome 15 open reading frame 26
chr17_+_69875140 0.532 NM_181790
GPR142
G protein-coupled receptor 142
chr10_-_85921703 0.526 LOC642934
hypothetical LOC642934
chr1_-_26571812 0.526 NM_001114759
NM_173574
ZNF683

zinc finger protein 683

chr19_+_7410573 0.526 NM_001130955
ARHGEF18
Rho/Rac guanine nucleotide exchange factor (GEF) 18
chr19_-_59516155 0.521 NM_181879
NM_181985
NM_181986
NM_021250
LILRA5



leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5



chr8_+_67507271 0.516 NM_144650
ADHFE1
alcohol dehydrogenase, iron containing, 1
chr11_+_118561375 0.514 NM_001168468
NM_024791
PDZD3

PDZ domain containing 3

chr17_+_69781980 0.506 NM_001172810
NM_023036
DNAI2

dynein, axonemal, intermediate chain 2

chr1_+_170656450 0.505 NM_139240
C1orf105
chromosome 1 open reading frame 105
chr3_+_46594079 0.505 NM_003212
TDGF1
teratocarcinoma-derived growth factor 1
chr14_-_94012266 0.496 NM_001042518
NM_175739
SERPINA9

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9

chr19_+_15024014 0.493 NM_012114
CASP14
caspase 14, apoptosis-related cysteine peptidase
chr6_-_105734535 0.492 NM_022361
POPDC3
popeye domain containing 3
chr4_-_140280031 0.490 NM_201999
ELF2
E74-like factor 2 (ets domain transcription factor)
chr19_-_39777329 0.488 NM_001025591
SCGBL
secretoglobin-like
chrX_-_102829621 0.484 NM_001142419
NM_001142420
NM_001142421
NM_001142422
NM_001142427
NM_001142428
NM_001142431
NM_001142432
MORF4L2







mortality factor 4 like 2







chr12_+_54361685 0.483 METTL7B
methyltransferase like 7B
chr8_-_134378630 0.483 NM_001135242
NM_006096
NDRG1

N-myc downstream regulated 1

chr9_-_135923373 0.475 BRD3
bromodomain containing 3
chr1_-_39910296 0.474 NM_032526
NT5C1A
5'-nucleotidase, cytosolic IA
chr9_+_128716867 0.473 NM_001190729
NM_001190730
NM_014636
RALGPS1


Ral GEF with PH domain and SH3 binding motif 1


chr8_-_134156353 0.468 SLA
Src-like-adaptor
chrX_-_102418329 0.465 NM_001012979
TCEAL5
transcription elongation factor A (SII)-like 5
chrX_-_49008115 0.463 NM_001114377
NM_014009
FOXP3

forkhead box P3

chr5_+_167846023 0.456 NM_002887
RARS
arginyl-tRNA synthetase
chr22_-_36836478 0.454 BAIAP2L2
BAI1-associated protein 2-like 2
chr7_+_116238309 0.453 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr14_+_100370559 0.453 MEG3
maternally expressed 3 (non-protein coding)
chr19_-_60528480 0.451 NM_001085488
TMEM150B
transmembrane protein 150B
chr10_+_6226764 0.448 NM_001145443
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr1_-_85515174 0.445 NM_003921
BCL10
B-cell CLL/lymphoma 10
chr16_+_22432344 0.443 NM_001135865
LOC100132247
NPIPL3
nuclear pore complex interacting protein related gene
nuclear pore complex interacting protein-like 3
chr7_+_123352521 0.433 NM_001174044
NM_003117
NM_153189
SPAM1


sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)


chr10_+_91082218 0.426 NM_001031683
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr18_-_51406359 0.423 TCF4
transcription factor 4
chr5_-_13997588 0.420 NM_001369
DNAH5
dynein, axonemal, heavy chain 5
chrX_-_99873152 0.417 NM_001174068
NM_080737
SYTL4

synaptotagmin-like 4

chr10_+_114033403 0.416 NM_058222
TECTB
tectorin beta
chr17_-_1211263 0.414 YWHAE
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr18_-_51406841 0.401 NM_001083962
NM_003199
TCF4

transcription factor 4

chr22_-_20314366 0.399 YDJC
YdjC homolog (bacterial)
chr13_+_99027366 0.398


chr2_+_45732416 0.398 NM_005400
PRKCE
protein kinase C, epsilon
chrX_-_131451675 0.398 NM_001170704
MBNL3
muscleblind-like 3 (Drosophila)
chr19_+_6086650 0.395 NM_030924
ACSBG2
acyl-CoA synthetase bubblegum family member 2
chr10_-_116276560 0.394 ABLIM1
actin binding LIM protein 1
chr1_+_149299490 0.391 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr7_+_68702252 0.390 AUTS2
autism susceptibility candidate 2
chr20_-_23010786 0.389 CD93
CD93 molecule
chr5_+_162862808 0.385 NM_182796
MAT2B
methionine adenosyltransferase II, beta
chr3_+_46258875 0.381 NM_001164680
NM_001837
NM_178328
NM_178329
CCR3



chemokine (C-C motif) receptor 3



chrX_+_30143595 0.380 NM_002364
MAGEB2
melanoma antigen family B, 2
chr14_+_103464504 0.378 NM_153046
TDRD9
tudor domain containing 9
chr19_+_53016910 0.375 NM_000554
CRX
cone-rod homeobox
chr5_-_169340321 0.375 NM_001129891
FAM196B
family with sequence similarity 196, member B
chr19_+_40849554 0.374 NM_007000
UPK1A
uroplakin 1A
chr2_-_73346215 0.365 FBXO41
F-box protein 41
chrX_-_31194867 0.362 NM_004015
NM_004016
NM_004017
NM_004018
NM_004019
DMD




dystrophin




chr11_+_117452936 0.362 NM_001083947
NM_001173551
NM_001173552
NM_019894
TMPRSS4



transmembrane protease, serine 4



chr10_+_91142301 0.358 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr6_-_32913797 0.354 TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr6_+_35308605 0.354 SCUBE3
signal peptide, CUB domain, EGF-like 3
chr11_-_58368555 0.349 NM_145016
GLYATL2
glycine-N-acyltransferase-like 2
chr1_-_44255583 0.349 NM_006934
NM_201649
SLC6A9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

chrX_+_85404626 0.346 NM_001139515
DACH2
dachshund homolog 2 (Drosophila)
chr18_-_63333487 0.345 DSEL
dermatan sulfate epimerase-like
chr1_+_149299307 0.342 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr5_+_68703036 0.342 NM_133339
RAD17
RAD17 homolog (S. pombe)
chr14_-_49629110 0.335 NM_001014830
C14orf183
chromosome 14 open reading frame 183
chr12_-_16650697 0.334 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr8_+_7340777 0.333 NM_001037668
NM_001040705
DEFB107A
DEFB107B
defensin, beta 107A
defensin, beta 107B
chrX_+_71047344 0.333 NM_001013627
NHSL2
NHS-like 2
chr1_+_166812466 0.331 NM_002995
XCL1
chemokine (C motif) ligand 1
chr9_-_96395828 0.330 NM_003837
FBP2
fructose-1,6-bisphosphatase 2
chr6_+_26071255 0.330 TRIM38
tripartite motif containing 38
chr20_-_44746529 0.329 NM_001011554
NM_001193340
SLC13A3

solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3

chr11_+_117452995 0.328 TMPRSS4
transmembrane protease, serine 4
chr19_+_54583286 0.326 NM_144688
CCDC155
coiled-coil domain containing 155
chr7_+_142346724 0.326 NM_178829
C7orf34
chromosome 7 open reading frame 34
chr22_-_37211467 0.323 DDX17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr19_-_55834895 0.322 NM_001160328
NM_001160329
SYT3

synaptotagmin III

chr5_-_175327555 0.318 THOC3
THO complex 3
chr6_+_29963328 0.317 HLA-H
major histocompatibility complex, class I, H (pseudogene)
chr12_+_121254042 0.316 NM_030765
B3GNT4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr7_+_5609416 0.311 FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr12_-_53314891 0.311 NM_033277
LACRT
lacritin
chr2_+_218833982 0.308 NM_001077191
NM_001077194
NM_170699
GPBAR1


G protein-coupled bile acid receptor 1


chr1_+_149299530 0.308 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chrX_+_110074124 0.307 NM_001128166
NM_001128167
PAK3

p21 protein (Cdc42/Rac)-activated kinase 3

chr1_-_203579932 0.306 KLHDC8A
kelch domain containing 8A
chr1_+_149299504 0.305 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr7_-_129868059 0.303 NM_018718
TSGA14
testis specific, 14
chr1_-_20318578 0.303 NM_012400
PLA2G2D
phospholipase A2, group IID
chr18_-_72857665 0.298 MBP
myelin basic protein
chrX_-_134257624 0.297 NM_001185063
NM_007131
ZNF75D

zinc finger protein 75D

chr7_+_100515439 0.297 NM_030961
TRIM56
tripartite motif containing 56
chr19_+_6981593 0.297 NM_001136507
MBD3L5
methyl-CpG-binding domain protein 3-like 5-like
chr12_-_28016182 0.297 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr9_+_27099138 0.295 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr15_-_80428760 0.294 NM_001164465
GOLGA6L10
golgin A6 family-like 10
chr4_-_141293572 0.293 MAML3
mastermind-like 3 (Drosophila)
chr12_-_55614311 0.293 NM_148897
SDR9C7
short chain dehydrogenase/reductase family 9C, member 7
chr3_+_39399770 0.291 NM_017875
SLC25A38
solute carrier family 25, member 38
chr12_+_103677388 0.290 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr22_-_16060485 0.288 NM_177405
CECR1
cat eye syndrome chromosome region, candidate 1
chr21_+_33320080 0.288 NM_005806
OLIG2
oligodendrocyte lineage transcription factor 2
chr16_-_4263001 0.286 NM_003223
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr7_-_44580661 0.284 NM_019082
DDX56
DEAD (Asp-Glu-Ala-Asp) box polypeptide 56
chr19_+_9222605 0.282 NM_001079935
OR7E24
olfactory receptor, family 7, subfamily E, member 24
chr17_-_17421503 0.280 NM_148173
PEMT
phosphatidylethanolamine N-methyltransferase
chr4_-_176970407 0.278 GPM6A
glycoprotein M6A
chr4_-_171247867 0.278 NM_182662
AADAT
aminoadipate aminotransferase
chr19_+_13111072 0.278 NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr17_-_24973940 0.277 CORO6
coronin 6
chr17_-_43390108 0.277 NM_024320
PRR15L
proline rich 15-like
chr7_+_128099581 0.275 NM_001012454
NM_001128926
FAM71F2

family with sequence similarity 71, member F2

chrX_-_131375217 0.274 NM_001170701
NM_001170702
NM_001170703
MBNL3


muscleblind-like 3 (Drosophila)


chr6_+_44076281 0.269 NM_001171992
NM_153246
C6orf223

chromosome 6 open reading frame 223

chr17_+_69833945 0.268 NM_153209
KIF19
kinesin family member 19
chr9_-_5175601 0.267 NM_007179
INSL6
insulin-like 6
chr2_-_88066423 0.265 NM_001024457
RGPD1
RANBP2-like and GRIP domain containing 1
chr3_+_190831909 0.264 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr8_-_101641046 0.264 NM_198401
GAPDHP62
ANKRD46
glyceraldehyde 3 phosphate dehydrogenase pseudogene 62
ankyrin repeat domain 46
chr12_+_48652886 0.264 NM_001652
AQP6
aquaporin 6, kidney specific
chr3_+_139549228 0.263 NM_012219
MRAS
muscle RAS oncogene homolog
chr20_+_61654816 0.262 NM_024059
C20orf195
chromosome 20 open reading frame 195
chrX_-_102829595 0.259 MORF4L2
mortality factor 4 like 2
chr19_+_12995782 0.257 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.