• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: PDX1.p2

Z-value: 0.549

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr3_-_21767819	0.788	NM_024697	ZNF385D	zinc finger protein 385D
chr10_+_63478974	0.768		ARID5B	AT rich interactive domain 5B (MRF1-like)
chr1_+_62835759	0.614	NM_014495	ANGPTL3	angiopoietin-like 3
chr15_+_46285789	0.517	NM_000338 NM_001184832	SLC12A1	solute carrier family 12 (sodium/potassium/chloride transporters), member 1
chr11_+_55899675	0.450	NM_001005204 NM_001013356	OR8U1 OR8U8	olfactory receptor, family 8, subfamily U, member 1 olfactory receptor, family 8, subfamily U, member 8
chr2_-_158008763	0.408	NM_004288	CYTIP	cytohesin 1 interacting protein
chr4_+_109033868	0.399	NM_001136257 NM_152621	SGMS2	sphingomyelin synthase 2
chr3_+_101720753	0.398		TMEM45A	transmembrane protein 45A
chr11_+_22652957	0.294		GAS2	growth arrest-specific 2
chr4_+_86615275	0.282	NM_001025616	ARHGAP24	Rho GTPase activating protein 24
chr6_+_130381408	0.273	NM_001007102 NM_032438	L3MBTL3	l(3)mbt-like 3 (Drosophila)
chr21_-_30781537	0.256	NM_181608	KRTAP19-2	keratin associated protein 19-2
chr11_-_123182266	0.252	NM_001005325	OR6M1	olfactory receptor, family 6, subfamily M, member 1
chr11_+_22652894	0.219	NM_005256	GAS2	growth arrest-specific 2
chr2_-_165768798	0.213	NM_001081676 NM_001081677 NM_006922	SCN3A	sodium channel, voltage-gated, type III, alpha subunit
chr5_+_34720368	0.204	NM_001145521 NM_001145525	RAI14	retinoic acid induced 14
chr19_+_41872141	0.195	NM_152603	ZNF567	zinc finger protein 567
chr4_-_69116839	0.190	NM_001077	UGT2B17	UDP glucuronosyltransferase 2 family, polypeptide B17
chr1_+_157246305	0.181	NM_005531	IFI16	interferon, gamma-inducible protein 16
chr5_+_147628567	0.174	NM_001040129	SPINK13	serine peptidase inhibitor, Kazal type 13 (putative)
chr17_-_36725470	0.170	NM_031964	KRTAP17-1	keratin associated protein 17-1
chr15_-_42756377	0.162	NM_001145112	PATL2	protein associated with topoisomerase II homolog 2 (yeast)
chr8_+_76614757	0.153	NM_004133	HNF4G	hepatocyte nuclear factor 4, gamma
chr4_+_95595419	0.150		PDLIM5	PDZ and LIM domain 5
chr9_+_33016482	0.150		DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1
chr1_+_36409277	0.142		MAP7D1	MAP7 domain containing 1
chr9_+_33614214	0.136		ANXA2P2	annexin A2 pseudogene 2
chr9_-_8723893	0.132	NM_001040712 NM_001171025 NM_130391 NM_130392 NM_130393	PTPRD	protein tyrosine phosphatase, receptor type, D
chr10_+_118177371	0.129	NM_001011709	PNLIPRP3	pancreatic lipase-related protein 3
chr11_-_5130174	0.121	NM_012375	OR52A1	olfactory receptor, family 52, subfamily A, member 1
chr4_+_123380569	0.120		KIAA1109	KIAA1109
chr1_-_156657279	0.119	NM_001004476	OR10K2	olfactory receptor, family 10, subfamily K, member 2
chr11_-_4924905	0.119	NM_001005329	OR51A4	olfactory receptor, family 51, subfamily A, member 4
chr8_-_17624304	0.119	NM_001166393	MTUS1	microtubule associated tumor suppressor 1
chr6_-_55848346	0.119		BMP5	bone morphogenetic protein 5
chr16_-_21078262	0.116	NM_017539	DNAH3	dynein, axonemal, heavy chain 3
chr17_-_36409632	0.114	NM_031959	KRTAP3-2	keratin associated protein 3-2
chr14_-_46882144	0.114	NM_182830	MDGA2	MAM domain containing glycosylphosphatidylinositol anchor 2
chr9_+_124416768	0.111	NM_012364	OR1Q1	olfactory receptor, family 1, subfamily Q, member 1
chr12_-_52306348	0.109	NM_001130060 NM_006856	ATF7	activating transcription factor 7
chr1_+_28637247	0.109	NM_023923	PHACTR4	phosphatase and actin regulator 4
chr16_+_18986417	0.108	NM_016138	COQ7	coenzyme Q7 homolog, ubiquinone (yeast)
chr12_-_52305900	0.105		ATF7	activating transcription factor 7
chr17_-_36403910	0.104	NM_033185	KRTAP3-3	keratin associated protein 3-3
chr13_-_109236897	0.103	NM_003749	IRS2	insulin receptor substrate 2
chr12_-_119938667	0.101	NM_022895	C12orf43	chromosome 12 open reading frame 43
chr8_+_32698892	0.101	NM_001159996	NRG1	neuregulin 1
chr17_+_7900926	0.101
chr14_+_100365162	0.100		MEG3	maternally expressed 3 (non-protein coding)
chr3_-_145049853	0.098	NM_173653	SLC9A9	solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr6_+_147566559	0.097		STXBP5	syntaxin binding protein 5 (tomosyn)
chr6_-_52060327	0.097	NM_138694 NM_170724	PKHD1	polycystic kidney and hepatic disease 1 (autosomal recessive)
chr4_+_74500748	0.096		ALB	albumin
chr1_+_69998445	0.094	NM_020794	LRRC7	leucine rich repeat containing 7
chr6_-_131333173	0.091		EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr18_-_49944986	0.088		MBD2	methyl-CpG binding domain protein 2
chr13_-_40491491	0.088	NM_172373	ELF1	E74-like factor 1 (ets domain transcription factor)
chr10_+_116687904	0.087	NM_139169	TRUB1	TruB pseudouridine (psi) synthase homolog 1 (E. coli)
chr21_-_44824907	0.086	NM_198694	KRTAP10-5	keratin associated protein 10-5
chr3_+_35697432	0.086	NM_198399	ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr14_+_20580224	0.083	NM_032572	RNASE7	ribonuclease, RNase A family, 7
chr2_-_218516950	0.082	NM_022648	TNS1	tensin 1
chr2_+_227900471	0.081	NM_020194	MFF	mitochondrial fission factor
chr12_-_119938593	0.081		C12orf43	chromosome 12 open reading frame 43
chr7_+_129057152	0.081	NM_001040110	NRF1	nuclear respiratory factor 1
chr3_+_116824840	0.080	NM_001130064 NM_002045	GAP43	growth associated protein 43
chr6_-_55848317	0.078	NM_021073	BMP5	bone morphogenetic protein 5
chr4_+_53975597	0.076		FIP1L1	FIP1 like 1 (S. cerevisiae)
chr14_-_76958984	0.076	NM_138791 NM_001113475	C14orf148	chromosome 14 open reading frame 148
chr3_+_176059763	0.075	NM_207015	NAALADL2	N-acetylated alpha-linked acidic dipeptidase-like 2
chr16_+_18986459	0.075		COQ7	coenzyme Q7 homolog, ubiquinone (yeast)
chr21_-_30666417	0.074	NM_181621	KRTAP13-2	keratin associated protein 13-2
chr5_+_140698537	0.074	NM_018915 NM_032009	PCDHGA2	protocadherin gamma subfamily A, 2
chr1_-_230717850	0.072	NM_020808	SIPA1L2	signal-induced proliferation-associated 1 like 2
chr17_+_32807040	0.071	NM_173625	C17orf78	chromosome 17 open reading frame 78
chr12_+_74071145	0.069	NM_152436	GLIPR1L2	GLI pathogenesis-related 1 like 2
chr2_-_199922047	0.068		SATB2	SATB homeobox 2
chr3_+_35658852	0.068	NM_016300	ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr11_+_111294810	0.066	NM_080659	C11orf52	chromosome 11 open reading frame 52
chr4_+_74825138	0.066	NM_000584	IL8	interleukin 8
chr10_-_108448990	0.065		SORCS1	sortilin-related VPS10 domain containing receptor 1
chr7_-_11643113	0.065		THSD7A	thrombospondin, type I, domain containing 7A
chr12_+_45896511	0.065		FAM113B	family with sequence similarity 113, member B
chr4_-_39199527	0.060		UGDH	UDP-glucose 6-dehydrogenase
chr12_+_79362256	0.059	NM_001145026	PTPRQ	protein tyrosine phosphatase, receptor type, Q
chr2_-_99412694	0.059		REV1	REV1 homolog (S. cerevisiae)
chr12_-_10853940	0.059	NM_023917	TAS2R9	taste receptor, type 2, member 9
chr1_-_31251315	0.058		PUM1	pumilio homolog 1 (Drosophila)
chr11_-_57883117	0.058	NM_001005489	OR5B17	olfactory receptor, family 5, subfamily B, member 17
chr17_-_39499527	0.056		LSM12	LSM12 homolog (S. cerevisiae)
chr11_+_55297489	0.056	NM_001001967	OR5D13	olfactory receptor, family 5, subfamily D, member 13
chr6_-_123999640	0.056	NM_006073	TRDN	triadin
chr7_+_116182676	0.053
chr9_-_21218132	0.048	NM_021268	IFNA17	interferon, alpha 17
chr16_-_70339666	0.047		AP1G1	adaptor-related protein complex 1, gamma 1 subunit
chr1_-_150328153	0.047	NM_001008536	TCHHL1	trichohyalin-like 1
chr10_+_90474280	0.045	NM_001080518	LIPK	lipase, family member K
chr17_-_36418869	0.043	NM_031958	KRTAP3-1	keratin associated protein 3-1
chr12_-_102968044	0.043	NM_031302	GLT8D2	glycosyltransferase 8 domain containing 2
chr5_+_179934143	0.043		CNOT6	CCR4-NOT transcription complex, subunit 6
chr2_+_185171480	0.042		ZNF804A	zinc finger protein 804A
chr16_+_18986721	0.042	NM_001190983	COQ7	coenzyme Q7 homolog, ubiquinone (yeast)
chr3_+_99350859	0.042	NM_001005514	OR5H14	olfactory receptor, family 5, subfamily H, member 14
chr12_+_10351683	0.041	NM_002262 NM_007334	KLRD1	killer cell lectin-like receptor subfamily D, member 1
chr1_-_246869181	0.041	NM_001001827	OR2T35	olfactory receptor, family 2, subfamily T, member 35
chr17_-_7023378	0.040	NM_001197216 NM_001671	ASGR1	asialoglycoprotein receptor 1
chr12_+_74071116	0.040		GLIPR1L2	GLI pathogenesis-related 1 like 2
chr1_-_202402043	0.040	NM_000537	REN	renin
chr10_-_56230953	0.039	NM_001142763 NM_001142764 NM_001142765 NM_001142766 NM_001142767 NM_001142768 NM_001142769 NM_001142770 NM_001142771 NM_001142772 NM_001142773 NM_033056	PCDH15	protocadherin-related 15
chr3_-_47909001	0.039		MAP4	microtubule-associated protein 4
chr18_-_28247193	0.039
chr8_+_11877238	0.038	NM_001033017	DEFB135	defensin, beta 135
chr3_-_110155237	0.038	NM_005459	GUCA1C	guanylate cyclase activator 1C
chr8_-_20084892	0.036	NM_001135691 NM_001142324 NM_001142325 NM_003053	SLC18A1	solute carrier family 18 (vesicular monoamine), member 1
chr4_+_169250281	0.035	NM_007193	ANXA10	annexin A10
chr2_+_203763649	0.035		RPL12	ribosomal protein L12
chr18_+_29573152	0.034		ASXL3	additional sex combs like 3 (Drosophila)
chr2_-_121964373	0.032		CLASP1	cytoplasmic linker associated protein 1
chr8_+_26569709	0.032		DPYSL2	dihydropyrimidinase-like 2
chr17_-_45629401	0.032
chr1_-_161379606	0.032		RGS5	regulator of G-protein signaling 5
chr7_+_104468614	0.031		MLL5	myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr1_-_159786441	0.031	NM_000569 NM_001127592	FCGR3A	Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr1_+_161305188	0.031	NM_005613	RGS4	regulator of G-protein signaling 4
chr2_+_105799354	0.031		NCK2	NCK adaptor protein 2
chr12_+_4569504	0.030	NM_003845	DYRK4	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr11_+_123639909	0.030	NM_001005198	OR8G5	olfactory receptor, family 8, subfamily G, member 5
chr7_+_93373755	0.029	NM_021955	GNGT1	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chrX_-_131375217	0.028	NM_001170701 NM_001170702 NM_001170703	MBNL3	muscleblind-like 3 (Drosophila)
chrX_+_123307812	0.028	NM_001114937 NM_002351	SH2D1A	SH2 domain containing 1A
chr2_+_169634330	0.027		DHRS9	dehydrogenase/reductase (SDR family) member 9
chrX_+_118592879	0.027		UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)
chr6_+_144654565	0.027	NM_007124	UTRN	utrophin
chr10_+_126620681	0.026	NM_017580	ZRANB1	zinc finger, RAN-binding domain containing 1
chr17_-_36444626	0.026	NM_030966	KRTAP1-3	keratin associated protein 1-3
chr7_+_156128431	0.026	NM_001184997	RNF32	ring finger protein 32
chr14_-_57133361	0.026	NM_001080455	SLC35F4	solute carrier family 35, member F4
chr6_-_26151863	0.026	NM_021062	HIST1H2BB	histone cluster 1, H2bb
chrX_+_118592568	0.026		UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)
chr11_+_6823458	0.026	NM_178168	OR10A5	olfactory receptor, family 10, subfamily A, member 5
chr12_+_21417068	0.025	NM_000415	IAPP	islet amyloid polypeptide
chr11_+_88550687	0.025	NM_000372	TYR	tyrosinase (oculocutaneous albinism IA)
chr3_+_149930656	0.025	NM_032049	AGTR1	angiotensin II receptor, type 1
chr4_+_187424336	0.024		F11	coagulation factor XI
chr12_-_101835510	0.024	NM_000277	PAH	phenylalanine hydroxylase
chr10_-_62002672	0.024		ANK3	ankyrin 3, node of Ranvier (ankyrin G)
chrX_-_62697473	0.023		LOC92249	hypothetical LOC92249
chr12_+_45896318	0.022	NM_138371	FAM113B	family with sequence similarity 113, member B
chr2_+_24660849	0.022	NM_003743 NM_147223 NM_147233	NCOA1	nuclear receptor coactivator 1
chr8_+_110443881	0.022	NM_177531	PKHD1L1	polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1
chr8_-_7331313	0.021	NM_152251 NM_001040704	DEFB106A DEFB106B	defensin, beta 106A defensin, beta 106B
chr2_+_38746742	0.021		GALM	galactose mutarotase (aldose 1-epimerase)
chr11_-_55661769	0.021	NM_001004064	OR8J3	olfactory receptor, family 8, subfamily J, member 3
chr2_+_17861266	0.019	NM_001105569	MSGN1	mesogenin 1
chr18_+_27152049	0.018	NM_001942	DSG1	desmoglein 1
chr21_-_30631882	0.018	NM_001077711	KRTAP27-1	keratin associated protein 27-1
chr1_-_150463292	0.018	NM_001009931	HRNR	hornerin
chr17_-_39499463	0.018		LSM12	LSM12 homolog (S. cerevisiae)
chr11_-_5178505	0.018	NM_001004760	OR51V1	olfactory receptor, family 51, subfamily V, member 1
chr4_+_77575276	0.017	NM_020859	SHROOM3	shroom family member 3
chr11_+_123945102	0.017	NM_001005194	OR8A1	olfactory receptor, family 8, subfamily A, member 1
chr19_-_55539769	0.017		NAPSB	napsin B aspartic peptidase pseudogene
chr1_-_245942679	0.017	NM_001005286	OR6F1	olfactory receptor, family 6, subfamily F, member 1
chr17_-_36559579	0.016	NM_033188	KRTAP4-5	keratin associated protein 4-5
chr8_-_17599438	0.015	NM_020749	MTUS1	microtubule associated tumor suppressor 1
chr1_-_33613729	0.015	NM_198040	PHC2	polyhomeotic homolog 2 (Drosophila)
chr3_+_49522871	0.015		DAG1	dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr2_-_183095308	0.015	NM_005019 NM_001003683	PDE1A	phosphodiesterase 1A, calmodulin-dependent
chr7_+_142459538	0.014	NM_001001667	OR6V1	olfactory receptor, family 6, subfamily V, member 1
chr4_-_155753249	0.013		FGG	fibrinogen gamma chain
chr11_+_89458765	0.013	NM_001143975	UBTFL1	upstream binding transcription factor, RNA polymerase I-like 1
chr11_-_55684368	0.013	NM_001004058	OR8K5	olfactory receptor, family 8, subfamily K, member 5
chr9_+_81377419	0.012		TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr1_-_159867781	0.012	NM_000570	FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr18_+_19286784	0.011	NM_003831	RIOK3	RIO kinase 3 (yeast)
chr14_+_57964462	0.011	NM_014749	KIAA0586	KIAA0586
chr4_+_187424111	0.011	NM_000128	F11	coagulation factor XI
chr9_+_96561750	0.010	NM_001193329	C9orf3	chromosome 9 open reading frame 3
chr1_+_161305558	0.010	NM_001113381	RGS4	regulator of G-protein signaling 4
chr11_-_116168316	0.010	NM_001166598 NM_052968	APOA5	apolipoprotein A-V
chr3_+_110024234	0.010	NM_016388	TRAT1	T cell receptor associated transmembrane adaptor 1
chr17_-_39500512	0.009	NM_152344	LSM12	LSM12 homolog (S. cerevisiae)
chr4_-_170314382	0.007		SH3RF1	SH3 domain containing ring finger 1
chr6_-_41362370	0.007	NM_018643	TREM1	triggering receptor expressed on myeloid cells 1
chr18_+_59374372	0.006	NM_080474	SERPINB12	serpin peptidase inhibitor, clade B (ovalbumin), member 12
chr1_+_184532027	0.006	NM_001127708 NM_001127709 NM_001127710 NM_005807	PRG4	proteoglycan 4
chr12_-_48902692	0.005	NM_001113547	LIMA1	LIM domain and actin binding 1
chr8_-_17624009	0.005	NM_001001931	MTUS1	microtubule associated tumor suppressor 1
chr21_-_30460841	0.005	NM_012131	CLDN17	claudin 17
chr4_-_140280031	0.004	NM_201999	ELF2	E74-like factor 2 (ets domain transcription factor)
chrX_+_99786044	0.003		SRPX2	sushi-repeat containing protein, X-linked 2
chr11_-_66201894	0.003		RBM4B	RNA binding motif protein 4B
chr14_+_38653177	0.002	NM_001009182 NM_001009183 NM_003616	SIP1	survival of motor neuron protein interacting protein 1
chr1_+_84382575	0.001		PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr12_+_10074542	0.001	NM_207345	CLEC9A	C-type lectin domain family 9, member A
chr9_+_140226457	0.001	NM_001145249	FAM157B	family with sequence similarity 157, member B
chr5_-_142795269	0.001	NM_001018074 NM_001018075 NM_001018077	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr17_-_26665213	0.001		EVI2B	ecotropic viral integration site 2B
chr8_+_92330691	0.000	NM_052832 NM_134266	SLC26A7	solute carrier family 26, member 7

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
4.87	7.80e-06	GO:0007608	sensory perception of smell
4.59	8.62e-06	GO:0007606	sensory perception of chemical stimulus
3.17	3.12e-04	GO:0007600	sensory perception
2.21	4.90e-03	GO:0003008	system process
2.35	8.05e-03	GO:0050877	neurological system process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
5.71	5.46e-04	GO:0045111	intermediate filament cytoskeleton
6.00	9.89e-04	GO:0005882	intermediate filament
1.62	2.88e-03	GO:0071944	cell periphery
2.08	1.33e-02	GO:0005856	cytoskeleton
1.56	1.47e-02	GO:0005886	plasma membrane
7.52	2.15e-02	GO:0045095	keratin filament
2.30	2.36e-02	GO:0044430	cytoskeletal part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
5.11	8.52e-07	GO:0004984	olfactory receptor activity
2.81	1.65e-03	GO:0004930	G-protein coupled receptor activity
2.09	4.85e-03	GO:0004872	receptor activity
1.92	9.56e-03	GO:0004871	signal transducer activity
1.92	9.56e-03	GO:0060089	molecular transducer activity
2.11	4.44e-02	GO:0004888	transmembrane receptor activity