Motif ID: PITX1..3.p2

Z-value: 1.495


Transcription factors associated with PITX1..3.p2:

Gene SymbolEntrez IDGene Name
PITX1 5307 paired-like homeodomain 1
PITX2 5308 paired-like homeodomain 2
PITX3 5309 paired-like homeodomain 3



Activity profile for motif PITX1..3.p2.

activity profile for motif PITX1..3.p2


Sorted Z-values histogram for motif PITX1..3.p2

Sorted Z-values for motif PITX1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PITX1..3.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_116196505 4.077 NM_030767
AKNA
AT-hook transcription factor
chr19_-_10152056 3.925


chr17_-_1037312 3.853 NM_001159746
ABR
active BCR-related gene
chr22_-_36305883 3.587 NM_006498
LGALS2
lectin, galactoside-binding, soluble, 2
chr22_+_40372957 3.575 XRCC6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr7_+_74962234 3.552 NM_001099435
SPDYE5
speedy homolog E5 (Xenopus laevis)
chr3_+_50259329 3.480 NM_001166425
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr19_+_53656317 3.447 NM_170720
KCNJ14
potassium inwardly-rectifying channel, subfamily J, member 14
chr17_-_10500189 3.421 NM_002470
MYH3
myosin, heavy chain 3, skeletal muscle, embryonic
chr17_+_29707583 3.392 NM_005408
CCL13
chemokine (C-C motif) ligand 13
chr11_+_35154775 3.333 CD44
CD44 molecule (Indian blood group)
chr19_-_2036227 3.298 MOBKL2A
MOB1, Mps One Binder kinase activator-like 2A (yeast)
chr16_+_48879323 3.246 NM_001114
ADCY7
adenylate cyclase 7
chr19_+_50287999 3.207 LRRC68
leucine rich repeat containing 68
chr19_-_5821546 3.191 NM_002034
FUT5
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr12_-_55042793 3.163 NM_001638
APOF
apolipoprotein F
chr17_-_30838870 3.021 NM_001195790
SLFN12L
schlafen family member 12-like
chr19_+_52532210 2.997 NM_018485
GPR77
G protein-coupled receptor 77
chr19_-_43926953 2.967 NM_144691
CAPN12
calpain 12
chr19_-_2207415 2.955 NM_144616
JSRP1
junctional sarcoplasmic reticulum protein 1
chr5_-_145503190 2.871 LARS
leucyl-tRNA synthetase
chr19_+_10083196 2.868 NM_002566
P2RY11
purinergic receptor P2Y, G-protein coupled, 11
chr6_+_31706345 2.866 PRRC2A
proline-rich coiled-coil 2A
chr17_-_71995401 2.857 NM_001005498
RHBDF2
rhomboid 5 homolog 2 (Drosophila)
chr1_-_154536051 2.778 NM_001004319
VHLL
von Hippel-Lindau tumor suppressor-like
chr12_-_131882616 2.769


chr19_-_5797465 2.734 FUT3
fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
chr19_+_16115454 2.701 HSH2D
hematopoietic SH2 domain containing
chr4_+_114330 2.688 ZNF718
zinc finger protein 718
chr16_+_30118036 2.662 NM_001017390
NM_177552
SULT1A4
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr19_+_50234135 2.636 NM_007056
CLASRP
CLK4-associating serine/arginine rich protein
chr22_-_27787793 2.608 NM_015370
C22orf31
chromosome 22 open reading frame 31
chr7_+_44007012 2.591 NM_175064
SPDYE1
speedy homolog E1 (Xenopus laevis)
chr19_-_8473473 2.562 NM_032152
PRAM1
PML-RARA regulated adaptor molecule 1
chr4_-_1185144 2.561 LOC100130872
hypothetical LOC100130872
chr1_-_226679648 2.520 NM_003493
HIST3H3
histone cluster 3, H3
chr19_-_54857003 2.500 IRF3
interferon regulatory factor 3
chr12_+_108149558 2.488 ACACB
acetyl-CoA carboxylase beta
chr19_-_50506883 2.465 CKM
creatine kinase, muscle
chr1_-_9040141 2.428 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr16_+_56230707 2.422 NM_001145774
GPR56
G protein-coupled receptor 56
chr22_+_19248733 2.414 MED15
mediator complex subunit 15
chr15_+_83160914 2.414 NM_020778
ALPK3
alpha-kinase 3
chr1_+_207668787 2.407 NM_001104548
LOC642587
NPC-A-5
chrX_-_70243362 2.400 NM_001025265
CXorf65
chromosome X open reading frame 65
chr11_+_65403859 2.333 NM_001335
CTSW
cathepsin W
chr17_+_69875140 2.323 NM_181790
GPR142
G protein-coupled receptor 142
chr9_+_6710862 2.319 NM_001146696
KDM4C
lysine (K)-specific demethylase 4C
chr3_+_188222337 2.301 NM_003032
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr7_+_5886952 2.266 NM_001097622
OCM
oncomodulin
chr19_-_5790702 2.252 NM_000150
NM_001040701
FUT6

fucosyltransferase 6 (alpha (1,3) fucosyltransferase)

chr19_+_49894260 2.229 NM_001039213
CEACAM16
carcinoembryonic antigen-related cell adhesion molecule 16
chr12_+_50568010 2.227 NM_001130015
NM_182608
ANKRD33

ankyrin repeat domain 33

chrX_+_102852492 2.209 NM_182541
TMEM31
transmembrane protein 31
chr17_-_44400952 2.200 NM_004123
GIP
gastric inhibitory polypeptide
chr19_+_14460757 2.189 NM_001146693
LOC100130932
small nuclear ribonucleoprotein G-like protein
chr4_+_1864306 2.162 NM_007331
NM_133330
NM_133331
NM_133335
WHSC1



Wolf-Hirschhorn syndrome candidate 1



chr4_+_6693282 2.161 NM_033296
MRFAP1
Morf4 family associated protein 1
chr19_-_17793312 2.149 NM_005543
INSL3
insulin-like 3 (Leydig cell)
chrX_-_18600108 2.116 NM_000330
RS1
retinoschisin 1
chr1_+_158387975 2.083 NM_144699
ATP1A4
ATPase, Na+/K+ transporting, alpha 4 polypeptide
chrX_-_114158388 2.081 NM_000640
IL13RA2
interleukin 13 receptor, alpha 2
chrX_-_129099695 2.080 NM_001130846
AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
chr19_+_49972965 2.079 NM_001130852
NM_012116
CBLC

Cas-Br-M (murine) ecotropic retroviral transforming sequence c

chr16_+_3499894 2.077 NM_024793
CLUAP1
clusterin associated protein 1
chr19_-_47638890 2.034 NM_198477
CXCL17
chemokine (C-X-C motif) ligand 17
chr8_-_124322764 2.026 NM_032847
C8orf76
chromosome 8 open reading frame 76
chr17_+_37340401 1.990 NM_031421
TTC25
tetratricopeptide repeat domain 25
chr1_-_159474503 1.986 NM_001077469
NM_001077470
NM_001077471
NM_001077472
NM_001077473
NM_001077474
NM_001077475
NM_001077476
NM_001077477
NM_001077478
NM_001077479
NM_001077480
NM_001077481
NM_001077482
NM_005122
NR1I3














nuclear receptor subfamily 1, group I, member 3














chr1_+_36409277 1.974 MAP7D1
MAP7 domain containing 1
chr11_+_118561375 1.973 NM_001168468
NM_024791
PDZD3

PDZ domain containing 3

chr15_+_40484249 1.947 NM_173089
NM_173090
CAPN3

calpain 3, (p94)

chr22_+_37747063 1.946 NM_152426
APOBEC3D
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
chr19_+_4134350 1.945 NM_133475
ANKRD24
ankyrin repeat domain 24
chr22_+_19248810 1.942 MED15
mediator complex subunit 15
chr12_-_47464143 1.940 NM_015270
ADCY6
adenylate cyclase 6
chr19_+_55571493 1.925 NM_007121
NR1H2
nuclear receptor subfamily 1, group H, member 2
chrX_-_71413804 1.924 NM_001007
RPS4X
ribosomal protein S4, X-linked
chr13_+_26896614 1.922 NM_002097
GTF3A
general transcription factor IIIA
chr19_+_13719677 1.920 NM_030818
CCDC130
coiled-coil domain containing 130
chr12_-_122160927 1.919 NM_020845
PITPNM2
phosphatidylinositol transfer protein, membrane-associated 2
chr22_-_16060485 1.918 NM_177405
CECR1
cat eye syndrome chromosome region, candidate 1
chr2_+_96566190 1.896 NM_212481
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr3_-_197422653 1.893 NM_001039617
ZDHHC19
zinc finger, DHHC-type containing 19
chr1_-_226357663 1.888 C1orf35
chromosome 1 open reading frame 35
chr16_-_2710552 1.878 NM_031948
PRSS27
protease, serine 27
chr19_+_3679373 1.876 NM_014428
TJP3
tight junction protein 3 (zona occludens 3)
chr16_+_65558878 1.873 NM_001185176
CES3
carboxylesterase 3
chr15_-_63199228 1.861 PDCD7
programmed cell death 7
chr17_+_38412267 1.853 NM_005533
IFI35
interferon-induced protein 35
chr10_+_70172257 1.836 CCAR1
cell division cycle and apoptosis regulator 1
chr7_-_98643024 1.825 NM_001145715
KPNA7
karyopherin alpha 7 (importin alpha 8)
chr17_+_17548888 1.813


chr19_-_18763077 1.810 NM_000095
COMP
cartilage oligomeric matrix protein
chr1_-_17180659 1.801 NM_001135247
NM_017459
MFAP2

microfibrillar-associated protein 2

chr11_-_62218759 1.800 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr19_+_2340768 1.795 NM_182973
TMPRSS9
transmembrane protease, serine 9
chr19_+_24061717 1.786 NM_203282
ZNF254
zinc finger protein 254
chr22_-_16070778 1.783 NM_017424
CECR1
cat eye syndrome chromosome region, candidate 1
chr22_-_23318829 1.770 NM_207644
C22orf36
chromosome 22 open reading frame 36
chr22_+_34443863 1.754 NM_030642
APOL5
apolipoprotein L, 5
chr5_-_16791346 1.754 MYO10
myosin X
chr22_+_36412277 1.748 NM_024313
NOL12
nucleolar protein 12
chr6_+_31538934 1.746 NM_006674
HCP5
HLA complex P5
chr14_-_49932366 1.709 NM_004196
CDKL1
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chr19_+_59705824 1.709 NM_002288
NM_021270
LAIR2

leukocyte-associated immunoglobulin-like receptor 2

chr7_+_156435163 1.708 NM_138400
NOM1
nucleolar protein with MIF4G domain 1
chr1_+_111573855 1.702 NM_001025199
CHI3L2
chitinase 3-like 2
chr19_-_56026559 1.685 NM_017509
NM_138563
NM_138564
KLK15


kallikrein-related peptidase 15


chr19_-_51889002 1.680 PRKD2
protein kinase D2
chr19_+_5641270 1.659 NM_033643
RPL36
ribosomal protein L36
chr11_+_68124400 1.652 PPP6R3
protein phosphatase 6, regulatory subunit 3
chr19_-_60241424 1.650 NM_001083899
NM_016363
GP6

glycoprotein VI (platelet)

chr1_-_172228673 1.645 NM_172071
RC3H1
ring finger and CCCH-type domains 1
chr7_-_6557591 1.637 NM_001145118
GRID2IP
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein
chr22_-_16026176 1.637 NM_017829
CECR5
cat eye syndrome chromosome region, candidate 5
chr11_-_66092534 1.636 NM_003793
CTSF
cathepsin F
chr1_+_6191506 1.628 RNF207
ring finger protein 207
chr1_+_10432362 1.623 NM_001302
CORT
cortistatin
chr15_+_41906403 1.611 NM_001167941
NM_024908
WDR76

WD repeat domain 76

chr12_-_44919818 1.611 SLC38A1
solute carrier family 38, member 1
chr17_+_7279485 1.606 NM_178518
TMEM102
transmembrane protein 102
chr19_+_15765760 1.606 NM_001004466
OR10H5
olfactory receptor, family 10, subfamily H, member 5
chr1_+_24713396 1.594 RCAN3
RCAN family member 3
chr2_-_27469947 1.594 FTH1P3
ferritin, heavy polypeptide 1 pseudogene 3
chr16_+_65552600 1.589 NM_001185177
NM_024922
CES3

carboxylesterase 3

chr11_-_117718532 1.588 NM_000732
NM_001040651
CD3D

CD3d molecule, delta (CD3-TCR complex)

chr19_+_17253453 1.587 NM_152363
ANKLE1
ankyrin repeat and LEM domain containing 1
chr6_+_167658563 1.580 NM_031949
TTLL2
tubulin tyrosine ligase-like family, member 2
chr19_-_3551576 1.572 TBXA2R
thromboxane A2 receptor
chrX_+_48915127 1.566 NM_002668
PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr7_+_1536847 1.563 NM_002360
MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr19_+_17723285 1.561 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr7_-_91632525 1.559 NM_001161528
LOC401387
leucine-rich repeat and death domain-containing protein
chr9_+_129962292 1.546 NM_024112
C9orf16
chromosome 9 open reading frame 16
chr19_-_44497815 1.543 NM_020862
LRFN1
leucine rich repeat and fibronectin type III domain containing 1
chr7_-_99899829 1.537 NM_001004323
C7orf61
chromosome 7 open reading frame 61
chr5_+_176744037 1.536 NM_001167579
NM_003052
SLC34A1

solute carrier family 34 (sodium phosphate), member 1

chr19_+_951295 1.532 NM_138690
GRIN3B
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
chr7_-_5787776 1.527 NM_207111
NM_207116
RNF216

ring finger protein 216

chr1_-_17253073 1.525 NM_003000
SDHB
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr19_+_7410573 1.520 NM_001130955
ARHGEF18
Rho/Rac guanine nucleotide exchange factor (GEF) 18
chr1_-_16006779 1.519 NM_001089591
UQCRHL
ubiquinol-cytochrome c reductase hinge protein-like
chr7_+_100169184 1.517 NM_003386
NM_173059
ZAN

zonadhesin

chr8_-_37847095 1.515 RAB11FIP1
RAB11 family interacting protein 1 (class I)
chr17_-_24062998 1.507 NM_152465
PROCA1
protein interacting with cyclin A1
chr5_-_139993469 1.501 NM_001040021
NM_001174104
NM_001174105
CD14


CD14 molecule


chrX_+_153101278 1.477 NM_000513
NM_001048181
OPN1MW
OPN1MW2
opsin 1 (cone pigments), medium-wave-sensitive
opsin 1 (cone pigments), medium-wave-sensitive 2
chr5_+_139907366 1.471 NM_003732
EIF4EBP3
eukaryotic translation initiation factor 4E binding protein 3
chr15_-_87565813 1.466 NM_000326
RLBP1
retinaldehyde binding protein 1
chr3_-_127810087 1.464 NM_001039783
TXNRD3IT1
thioredoxin reductase 3 intronic transcript 1
chr8_-_33544184 1.460 NM_024787
RNF122
ring finger protein 122
chr19_+_53770804 1.460 NM_004605
SULT2B1
sulfotransferase family, cytosolic, 2B, member 1
chr16_+_70599987 1.457 NM_001361
DHODH
dihydroorotate dehydrogenase
chr22_-_48835181 1.453 NM_001080447
TTLL8
tubulin tyrosine ligase-like family, member 8
chr16_-_2254318 1.451 RNPS1
RNA binding protein S1, serine-rich domain
chr7_+_101978777 1.451 NM_001166339
NM_001031618
SPDYE2L
SPDYE2
WBSCR19-like protein 3
speedy homolog E2 (Xenopus laevis)
chr1_+_154297588 1.448 NM_020387
RAB25
RAB25, member RAS oncogene family
chrX_-_48866963 1.445 NM_015698
GPKOW
G patch domain and KOW motifs
chr9_-_134271985 1.437 NM_007344
TTF1
transcription termination factor, RNA polymerase I
chr1_-_109201228 1.432 NM_152763
AKNAD1
AKNA domain containing 1
chr1_-_226357552 1.426 NM_024319
C1orf35
chromosome 1 open reading frame 35
chr2_-_46988449 1.421 MCFD2
multiple coagulation factor deficiency 2
chr17_-_76897590 1.418 NM_178519
C17orf55
chromosome 17 open reading frame 55
chr1_-_142309117 1.417


chr5_+_132460779 1.416 HSPA4
heat shock 70kDa protein 4
chr11_-_66431910 1.413 NM_022172
PC
pyruvate carboxylase
chr19_+_8335010 1.410 NM_001039667
NM_139314
ANGPTL4

angiopoietin-like 4

chrX_-_2892288 1.406 NM_000047
ARSE
arylsulfatase E (chondrodysplasia punctata 1)
chr7_+_72486044 1.404 NM_003508
FZD9
frizzled homolog 9 (Drosophila)
chr22_+_29122932 1.402 NM_012429
NM_033382
SEC14L2

SEC14-like 2 (S. cerevisiae)

chr3_+_9666184 1.401 MTMR14
myotubularin related protein 14
chr11_-_73397929 1.392 NM_003356
NM_022803
UCP3

uncoupling protein 3 (mitochondrial, proton carrier)

chr19_+_48912053 1.391 NM_019612
IRGC
immunity-related GTPase family, cinema
chr10_+_126140330 1.390 NM_001167880
NM_022126
LHPP

phospholysine phosphohistidine inorganic pyrophosphate phosphatase

chr15_-_28472854 1.382 NM_139320
NM_148911
CHRFAM7A

CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion

chr8_-_27997306 1.380 NM_001010906
C8orf80
chromosome 8 open reading frame 80
chr1_+_3658821 1.376 NM_152492
CCDC27
coiled-coil domain containing 27
chr17_+_17931924 1.355 NM_001388
DRG2
developmentally regulated GTP binding protein 2
chr10_+_135057597 1.342 NM_138384
MTG1
mitochondrial GTPase 1 homolog (S. cerevisiae)
chr1_+_159032551 1.340 NM_001033667
NM_002348
LY9

lymphocyte antigen 9

chr6_-_31960735 1.338 EHMT2
euchromatic histone-lysine N-methyltransferase 2
chr2_+_96365190 1.337 NM_015341
NCAPH
non-SMC condensin I complex, subunit H
chr4_-_40212670 1.337 NM_019027
RBM47
RNA binding motif protein 47
chrX_-_138875342 1.335 NM_001013403
CXorf66
chromosome X open reading frame 66
chr3_+_9666198 1.331 MTMR14
myotubularin related protein 14
chr1_+_40486159 1.327 NM_001008740
TMCO2
transmembrane and coiled-coil domains 2
chr4_-_38710376 1.327 NM_024943
TMEM156
transmembrane protein 156
chr6_-_143874463 1.323 NM_032020
FUCA2
fucosidase, alpha-L- 2, plasma
chr19_-_3431514 1.322 NM_001136503
C19orf77
chromosome 19 open reading frame 77
chr1_+_234748187 1.321 NM_201545
LGALS8
lectin, galactoside-binding, soluble, 8
chr1_-_148959945 1.321 NM_032132
HORMAD1
HORMA domain containing 1
chr2_-_97016027 1.314 NM_001122646
FAM178B
family with sequence similarity 178, member B
chr3_+_52212969 1.307 ALAS1
aminolevulinate, delta-, synthase 1
chr12_-_6535481 1.302 NM_001039670
NM_001193457
NM_080730
IFFO1


intermediate filament family orphan 1


chr10_-_69957589 1.296 NM_152707
SLC25A16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr4_-_77081118 1.291 NM_001042402
NM_014435
NAAA

N-acylethanolamine acid amidase

chr3_-_130600931 1.289 RPL32P3
ribosomal protein L32 pseudogene 3
chr10_-_125843092 1.288 CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr12_-_116021473 1.272 NM_001168325
NM_017899
TESC

tescalcin


Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.