Motif ID: RBPJ.p2

Z-value: 1.227


Transcription factors associated with RBPJ.p2:

Gene SymbolEntrez IDGene Name
RBPJ 3516 recombination signal binding protein for immunoglobulin kappa J region



Activity profile for motif RBPJ.p2.

activity profile for motif RBPJ.p2


Sorted Z-values histogram for motif RBPJ.p2

Sorted Z-values for motif RBPJ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RBPJ.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_67965517 1.389 NM_004429
EFNB1
ephrin-B1
chr17_+_71232370 1.187 NM_001005619
ITGB4
integrin, beta 4
chrX_-_19050499 1.074 NM_001079858
NM_001079859
NM_001079860
NM_001184833
NM_001184834
NM_001184835
NM_001184836
NM_001184837
NM_005756
GPR64








G protein-coupled receptor 64








chrX_+_48219344 0.972 NM_012280
NM_177439
FTSJ1

FtsJ homolog 1 (E. coli)

chr12_-_53059234 0.913 ZNF385A
zinc finger protein 385A
chr11_+_66952462 0.853 NM_003952
RPS6KB2
ribosomal protein S6 kinase, 70kDa, polypeptide 2
chr1_+_141560298 0.784


chr16_+_67698943 0.762 NM_005329
HAS3
hyaluronan synthase 3
chr17_+_77910411 0.704 NM_207459
TEX19
testis expressed 19
chr17_-_23716391 0.703 NM_001080837
SEBOX
SEBOX homeobox
chrX_+_24393264 0.660 NM_001142386
NM_005391
PDK3

pyruvate dehydrogenase kinase, isozyme 3

chrX_+_35974973 0.641 NM_173695
CXorf59
chromosome X open reading frame 59
chr7_+_47661366 0.637 NM_001123065
C7orf65
chromosome 7 open reading frame 65
chrX_-_106033202 0.628 NM_001171706
NM_138382
RIPPLY1

ripply1 homolog (zebrafish)

chr21_+_45699830 0.621 NM_030582
NM_130444
COL18A1

collagen, type XVIII, alpha 1

chrX_-_54841397 0.580 NM_198510
ITIH5L
inter-alpha (globulin) inhibitor H5-like
chr11_+_65414677 0.580 CCDC85B
coiled-coil domain containing 85B
chr11_+_61204392 0.561 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr6_-_71069347 0.557 NM_001851
COL9A1
collagen, type IX, alpha 1
chrX_+_102727068 0.540 NM_001006935
NM_001006937
NM_024863
TCEAL4


transcription elongation factor A (SII)-like 4


chr19_+_60580015 0.528 NM_139172
TMEM190
transmembrane protein 190
chr5_+_178383381 0.524 NM_001136116
ZNF879
zinc finger protein 879
chrX_+_71047344 0.517 NM_001013627
NHSL2
NHS-like 2
chrX_-_70248022 0.516 NM_000206
IL2RG
interleukin 2 receptor, gamma
chr10_-_42368035 0.504 ZNF37BP
zinc finger protein 37B, pseudogene
chr3_+_173043832 0.495 NM_001164436
TMEM212
transmembrane protein 212
chr14_-_60185659 0.494 NM_005982
SIX1
SIX homeobox 1
chr20_-_61933012 0.491 ZBTB46
zinc finger and BTB domain containing 46
chr11_+_35154775 0.479 CD44
CD44 molecule (Indian blood group)
chrX_-_16798096 0.477 RBBP7
retinoblastoma binding protein 7
chr3_+_16191159 0.476 NM_054110
GALNTL2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2
chr1_-_41259973 0.476 NM_001168247
NM_144990
SLFNL1

schlafen-like 1

chr16_+_56219802 0.471 NM_001145771
NM_001145772
NM_001145773
NM_201524
NM_201525
GPR56




G protein-coupled receptor 56




chrX_-_103288263 0.461 NM_001012755
MCART6
mitochondrial carrier triple repeat 6
chr11_+_2378559 0.460 TSSC4
tumor suppressing subtransferable candidate 4
chr15_+_57517564 0.455 NM_152450
FAM81A
family with sequence similarity 81, member A
chrX_-_48866963 0.445 NM_015698
GPKOW
G patch domain and KOW motifs
chr3_+_185499732 0.445 PSMD2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr11_-_31796061 0.444 NM_001127612
PAX6
paired box 6
chr10_+_103882776 0.440 NM_015062
PPRC1
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr11_+_65414450 0.435 NM_006848
CCDC85B
coiled-coil domain containing 85B
chrX_+_19271931 0.431 NM_000284
NM_001173454
NM_001173455
NM_001173456
PDHA1



pyruvate dehydrogenase (lipoamide) alpha 1



chr6_-_27548438 0.431 NM_007149
ZNF184
zinc finger protein 184
chrX_-_21586337 0.424 NM_153270
KLHL34
kelch-like 34 (Drosophila)
chr7_-_100325209 0.424 NM_001015072
UFSP1
UFM1-specific peptidase 1 (non-functional)
chrX_-_118809584 0.409 NM_001000
RPL39
ribosomal protein L39
chr6_-_17814596 0.407 NM_005124
NUP153
nucleoporin 153kDa
chr1_+_114323552 0.406 NM_020190
OLFML3
olfactomedin-like 3
chr3_+_185499679 0.404 NM_002808
PSMD2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr16_+_517834 0.403 NM_005632
SOLH
small optic lobes homolog (Drosophila)
chrX_-_111970662 0.403 NM_133265
AMOT
angiomotin
chrX_-_49008115 0.402 NM_001114377
NM_014009
FOXP3

forkhead box P3

chr16_+_23673448 0.398 NM_022097
CHP2
calcineurin B homologous protein 2
chrX_+_114330218 0.396 NM_001145346
RBMXL3
RNA binding motif protein, X-linked-like 3
chr7_+_100169184 0.396 NM_003386
NM_173059
ZAN

zonadhesin

chr19_+_54837181 0.395 NM_021228
SCAF1
SR-related CTD-associated factor 1
chr1_-_21478571 0.395 NM_001113347
ECE1
endothelin converting enzyme 1
chr19_-_48835783 0.383 NM_145296
CADM4
cell adhesion molecule 4
chrX_-_73751185 0.382 NM_016120
NM_183353
RLIM

ring finger protein, LIM domain interacting

chr21_-_14677310 0.382 NM_006948
HSPA13
heat shock protein 70kDa family, member 13
chr8_-_120914233 0.380 NM_003184
TAF2
TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
chr22_+_25398690 0.378 LOC388889
hypothetical LOC388889
chr11_-_2118916 0.374 NM_001127598
IGF2
insulin-like growth factor 2 (somatomedin A)
chr11_-_2248757 0.373 NM_005170
ASCL2
achaete-scute complex homolog 2 (Drosophila)
chr11_+_43920385 0.373 NM_001145033
C11orf96
chromosome 11 open reading frame 96
chr11_+_66841885 0.369 LOC100130987
similar to hCG1815675
chr3_-_75917351 0.368 ZNF717
zinc finger protein 717
chr1_-_158948176 0.367 NM_001778
CD48
CD48 molecule
chr20_+_31783426 0.361 NM_032819
ZNF341
zinc finger protein 341
chr7_+_116182676 0.360


chrX_-_73751152 0.359


chrX_-_73751135 0.359 RLIM
ring finger protein, LIM domain interacting
chr7_+_149042960 0.359 NM_032534
KRBA1
KRAB-A domain containing 1
chrX_+_16051344 0.358 NM_005314
GRPR
gastrin-releasing peptide receptor
chr10_-_105427898 0.354 SH3PXD2A
SH3 and PX domains 2A
chr19_-_5631502 0.352 C19orf70
chromosome 19 open reading frame 70
chr11_-_32408934 0.352 NM_001198551
NM_001198552
WT1

Wilms tumor 1

chrX_+_23982981 0.347 NM_001415
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr17_+_71235324 0.347 ITGB4
integrin, beta 4
chr12_-_131816604 0.347 ANKLE2
ankyrin repeat and LEM domain containing 2
chrX_+_105932536 0.346 NM_017752
NM_198881
TBC1D8B

TBC1 domain family, member 8B (with GRAM domain)

chr17_-_39447817 0.343 NM_032376
TMEM101
transmembrane protein 101
chrX_+_150635162 0.342 NM_033085
FATE1
fetal and adult testis expressed 1
chr14_-_89868006 0.340 NM_017970
NM_199043
C14orf102

chromosome 14 open reading frame 102

chrX_-_107221405 0.336 NM_002814
NM_170750
PSMD10

proteasome (prosome, macropain) 26S subunit, non-ATPase, 10

chr16_+_80301165 0.335 CMIP
c-Maf-inducing protein
chr22_-_45311730 0.335 NM_014246
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chrX_-_40479893 0.326 MED14
mediator complex subunit 14
chr22_+_19239221 0.321 MED15
mediator complex subunit 15
chrX_+_23982992 0.320 EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr15_-_41409979 0.319 NM_014793
LCMT2
leucine carboxyl methyltransferase 2
chr6_+_31190505 0.312 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr17_+_8865547 0.311 NM_004822
NTN1
netrin 1
chr19_+_58715988 0.308 NM_018555
ZNF331
zinc finger protein 331
chr3_-_51884639 0.307 NM_001145059
IQCF5
IQ motif containing F5
chrX_-_73751155 0.306 RLIM
ring finger protein, LIM domain interacting
chr15_+_89061579 0.304 NM_000057
BLM
Bloom syndrome, RecQ helicase-like
chr3_-_52839727 0.301 NM_001166449
NM_002218
ITIH4

inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)

chr19_-_60320592 0.300 NM_017607
PPP1R12C
protein phosphatase 1, regulatory (inhibitor) subunit 12C
chr19_-_41561904 0.299 NM_020917
ZFP14
zinc finger protein 14 homolog (mouse)
chr6_-_169392771 0.299


chr15_+_42815851 0.298 NM_080745
NM_182985
TRIM69

tripartite motif containing 69

chr3_-_114047479 0.297 NM_001008784
CD200R1L
CD200 receptor 1-like
chr3_-_49868889 0.291 NM_005879
TRAIP
TRAF interacting protein
chrX_-_134883500 0.290 MMGT1
membrane magnesium transporter 1
chrX_-_134883798 0.288 NM_173470
MMGT1
membrane magnesium transporter 1
chr9_-_129752687 0.282 NM_203305
FAM102A
family with sequence similarity 102, member A
chr9_-_99001551 0.282 NM_199005
ZNF322B
ZNF322A
zinc finger protein 322B
zinc finger protein 322A
chr11_-_2118743 0.282 IGF2
insulin-like growth factor 2 (somatomedin A)
chr7_+_1543644 0.279 MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr8_+_22465171 0.277 NM_005775
SORBS3
sorbin and SH3 domain containing 3
chr7_+_138469029 0.277 NM_001144920
NM_001144923
NM_024926
TTC26


tetratricopeptide repeat domain 26


chr11_-_2248374 0.275 ASCL2
achaete-scute complex homolog 2 (Drosophila)
chrX_-_31194867 0.272 NM_004015
NM_004016
NM_004017
NM_004018
NM_004019
DMD




dystrophin




chr1_-_195302973 0.271 NM_001994
F13B
coagulation factor XIII, B polypeptide
chr8_+_82807218 0.266 NM_152284
CHMP4C
chromatin modifying protein 4C
chr3_-_51508946 0.266 VPRBP
Vpr (HIV-1) binding protein
chrX_-_30505804 0.266 NM_025159
CXorf21
chromosome X open reading frame 21
chrX_-_52913823 0.265 NM_133179
XAGE3
X antigen family, member 3
chr22_-_17512097 0.264 DGCR14
DiGeorge syndrome critical region gene 14
chr19_-_59368625 0.263 NM_001145303
NM_144686
TMC4

transmembrane channel-like 4

chr14_+_60045621 0.263 NM_007374
SIX6
SIX homeobox 6
chrX_-_152863251 0.262 NM_002910
RENBP
renin binding protein
chr19_-_17349096 0.262 NM_031310
PLVAP
plasmalemma vesicle associated protein
chr4_-_1655515 0.260 NM_001013622
NM_001174070
FAM53A

family with sequence similarity 53, member A

chrX_-_77037563 0.259 NM_032121
MAGT1
magnesium transporter 1
chr19_-_53914768 0.256 NM_001130915
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chrX_-_135941498 0.255 NM_054021
GPR101
G protein-coupled receptor 101
chrX_-_71709335 0.255 HDAC8
histone deacetylase 8
chr6_+_43565192 0.254 NM_001146017
TJAP1
tight junction associated protein 1 (peripheral)
chr8_+_144870482 0.253 NM_139021
MAPK15
mitogen-activated protein kinase 15
chr1_+_23990228 0.253 NM_007260
LYPLA2
lysophospholipase II
chrX_-_16798363 0.252 RBBP7
retinoblastoma binding protein 7
chr11_-_113251415 0.252 NM_020886
USP28
ubiquitin specific peptidase 28
chr16_+_56259657 0.251 NM_170776
GPR97
G protein-coupled receptor 97
chr1_-_2451543 0.250 NM_001010926
HES5
hairy and enhancer of split 5 (Drosophila)
chr22_-_17512174 0.249 NM_022719
DGCR14
DiGeorge syndrome critical region gene 14
chr16_-_30705707 0.243 NM_001080417
ZNF629
zinc finger protein 629
chr6_+_44076281 0.243 NM_001171992
NM_153246
C6orf223

chromosome 6 open reading frame 223

chrX_+_103181171 0.241 NM_001164416
H2BFM
H2B histone family, member M
chrX_+_23711195 0.241 NM_002970
SAT1
spermidine/spermine N1-acetyltransferase 1
chr10_-_32707549 0.240 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chrX_-_152749190 0.239 NM_032512
PDZD4
PDZ domain containing 4
chr4_+_191226073 0.239 NM_012147
NM_001177376
NM_001127388
NM_001127389
NM_001164467
DUX2
DUX4L4
DUX4L6
DUX4L5
DUX4L3
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
chr17_+_19255083 0.238 NM_007148
RNF112
ring finger protein 112
chr19_+_5632016 0.237 NM_198704
NM_198705
NM_198533
NM_198707
NM_198706
NM_198708
HSD11B1L





hydroxysteroid (11-beta) dehydrogenase 1-like





chr18_+_75724655 0.236 NM_012283
KCNG2
potassium voltage-gated channel, subfamily G, member 2
chrX_+_23711352 0.235 SAT1
spermidine/spermine N1-acetyltransferase 1
chrX_-_128485062 0.235 SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chrX_-_40480005 0.233 MED14
mediator complex subunit 14
chr12_+_54910086 0.233 NM_173596
SLC39A5
solute carrier family 39 (metal ion transporter), member 5
chr17_-_25642962 0.231 NM_000386
BLMH
bleomycin hydrolase
chr10_-_92670764 0.230 ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chrX_-_152749035 0.228 PDZD4
PDZ domain containing 4
chr12_+_6431437 0.228 NM_018009
TAPBPL
TAP binding protein-like
chrX_-_111953009 0.227 NM_001113490
AMOT
angiomotin
chr19_+_55398680 0.225 NM_001077186
NM_001145809
NM_024729
MYH14


myosin, heavy chain 14, non-muscle


chr4_+_186176988 0.222 NM_001029887
HELT
HES/HEY-like transcription factor
chr9_+_124602190 0.219 NM_080859
OR1K1
olfactory receptor, family 1, subfamily K, member 1
chr19_-_56549853 0.218 NM_001014763
ETFB
electron-transfer-flavoprotein, beta polypeptide
chr19_+_42099073 0.217 NM_198539
ZNF568
zinc finger protein 568
chr19_-_49500966 0.215 NM_004234
ZNF235
zinc finger protein 235
chrX_-_128485121 0.213 SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr19_+_12941431 0.212 NM_152654
DAND5
DAN domain family, member 5
chr22_+_19191964 0.212 MED15
mediator complex subunit 15
chr17_-_33178987 0.210 HNF1B
HNF1 homeobox B
chr12_+_48630790 0.209 NM_000486
AQP2
aquaporin 2 (collecting duct)
chr13_-_24395054 0.207 NM_018451
CENPJ
centromere protein J
chr14_-_52487558 0.204 NM_001134999
NM_001135000
NM_006832
FERMT2


fermitin family member 2


chr3_+_101019357 0.203 NM_032359
C3orf26
chromosome 3 open reading frame 26
chr4_+_191235959 0.202 NM_001177376
DUX4L4
double homeobox 4 like 4
chr19_-_39859997 0.201


chr5_+_137542652 0.201 KIF20A
kinesin family member 20A
chr3_-_137953876 0.200 NM_005862
STAG1
stromal antigen 1
chrX_-_128485134 0.198 NM_003069
NM_139035
SMARCA1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1

chr1_+_26609893 0.197 LIN28A
lin-28 homolog A (C. elegans)
chr1_-_54291503 0.197 TMEM59
transmembrane protein 59
chr22_+_21027538 0.196


chr22_-_35428848 0.196 NM_006078
CACNG2
calcium channel, voltage-dependent, gamma subunit 2
chr7_-_76667045 0.195 NM_006682
FGL2
fibrinogen-like 2
chr17_-_23950171 0.195 NM_006461
SPAG5
sperm associated antigen 5
chrX_+_153186602 0.195 NM_001145934
TKTL1
transketolase-like 1
chrX_+_136475979 0.193 NM_003413
ZIC3
Zic family member 3 (odd-paired homolog, Drosophila)
chr11_+_19328846 0.193 NM_001111018
NAV2
neuron navigator 2
chr4_+_191239247 0.192 NM_033178
NM_012147
NM_001177376
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr10_-_75304225 0.192 NM_001222
NM_172169
NM_172171
NM_172173
NM_172170
CAMK2G




calcium/calmodulin-dependent protein kinase II gamma




chr7_+_30777512 0.192 NM_032222
FAM188B
family with sequence similarity 188, member B
chr15_+_20507195 0.192 NM_001033028
CYFIP1
cytoplasmic FMR1 interacting protein 1
chr17_+_1586034 0.190 WDR81
WD repeat domain 81
chr12_-_51585004 0.190 NM_002273
KRT8
keratin 8
chr4_+_191229360 0.189 NM_033178
NM_012147
NM_001177376
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr17_+_72795567 0.189 NM_001113492
SEPT9
septin 9
chr17_+_31415752 0.188 NM_002988
CCL18
chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
chr1_+_44870256 0.188 RNF220
ring finger protein 220
chr10_+_135343649 0.187 NM_012147
DUX2
double homeobox 2
chr9_+_138900760 0.187 NM_021138
TRAF2
TNF receptor-associated factor 2
chr1_+_180836050 0.187


chr1_+_12627152 0.186 NM_001013630
AADACL4
arylacetamide deacetylase-like 4
chr19_-_63150825 0.186 NM_005773
ZNF256
zinc finger protein 256
chrX_+_30169977 0.185 NM_002367
MAGEB4
melanoma antigen family B, 4

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.37 7.14e-04 GO:0006355 regulation of transcription, DNA-dependent
1.33 1.28e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.34 1.49e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.32 1.25e-02 GO:0051252 regulation of RNA metabolic process
1.28 3.85e-02 GO:0010468 regulation of gene expression
1.27 4.61e-02 GO:0031326 regulation of cellular biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.23 8.29e-07 GO:0005634 nucleus
1.14 8.94e-06 GO:0043231 intracellular membrane-bounded organelle
1.14 1.13e-05 GO:0043227 membrane-bounded organelle
1.12 8.74e-05 GO:0043229 intracellular organelle
1.12 9.67e-05 GO:0043226 organelle
1.08 1.77e-03 GO:0044424 intracellular part
1.07 1.46e-02 GO:0005622 intracellular

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.36 4.65e-05 GO:0003677 DNA binding
1.29 5.52e-05 GO:0003676 nucleic acid binding
1.07 1.56e-02 GO:0005488 binding
1.28 4.51e-02 GO:0008270 zinc ion binding