Motif ID: SNAI1..3.p2

Z-value: 2.009


Transcription factors associated with SNAI1..3.p2:

Gene SymbolEntrez IDGene Name
SNAI1 6615 snail homolog 1 (Drosophila)
SNAI2 6591 snail homolog 2 (Drosophila)
SNAI3 333929 snail homolog 3 (Drosophila)



Activity profile for motif SNAI1..3.p2.

activity profile for motif SNAI1..3.p2


Sorted Z-values histogram for motif SNAI1..3.p2

Sorted Z-values for motif SNAI1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SNAI1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_241484245 3.139 NM_001085437
C2orf54
chromosome 2 open reading frame 54
chr7_-_72761367 2.749 STX1A
syntaxin 1A (brain)
chr1_+_3360880 2.449 NM_014448
ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr8_+_143542378 2.437 NM_001702
BAI1
brain-specific angiogenesis inhibitor 1
chr19_+_43447078 2.367 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_6415259 2.287 NM_139161
NM_174881
CRB3

crumbs homolog 3 (Drosophila)

chr19_-_60587414 2.224 NM_001190764
LOC388564
hypothetical protein LOC388564
chr19_+_43446937 2.223 NM_001166103
NM_021102
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr1_-_1840564 2.132 NM_178545
TMEM52
transmembrane protein 52
chr19_+_43447262 2.120 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr6_+_31891293 2.054 HSPA1A
heat shock 70kDa protein 1A
chr6_+_31891509 2.031 HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr6_+_31903374 1.834 NM_005346
HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr17_+_69875140 1.807 NM_181790
GPR142
G protein-coupled receptor 142
chr22_+_20067662 1.805 NM_001128633
RIMBP3C
RIMS binding protein 3C
chr1_+_199130571 1.793 NM_001142569
C1orf106
chromosome 1 open reading frame 106
chr22_+_21027538 1.744


chr16_+_87232501 1.719 NM_013278
IL17C
interleukin 17C
chr17_-_77635703 1.716 FASN
fatty acid synthase
chr1_+_1062137 1.715 LOC254099
hypothetical protein LOC254099
chr22_+_21318779 1.703 NM_199127
GGTLC2
gamma-glutamyltransferase light chain 2
chr11_+_119616112 1.702 NM_014352
POU2F3
POU class 2 homeobox 3
chr14_+_104402626 1.684 NM_001112726
NM_015005
KIAA0284

KIAA0284

chr1_+_226399026 1.679 NM_001159391
GUK1
guanylate kinase 1
chr6_-_44333002 1.671 NM_178148
SLC35B2
solute carrier family 35, member B2
chr19_-_3928516 1.643 EEF2
eukaryotic translation elongation factor 2
chr8_+_145692916 1.634 NM_032902
PPP1R16A
protein phosphatase 1, regulatory (inhibitor) subunit 16A
chr19_-_3931499 1.630 EEF2
eukaryotic translation elongation factor 2
chr17_+_71235324 1.619 ITGB4
integrin, beta 4
chr12_+_120944174 1.606 NM_001024808
NM_020993
BCL7A

B-cell CLL/lymphoma 7A

chr5_+_169465478 1.591 NM_012188
NM_144769
FOXI1

forkhead box I1

chr17_-_77092569 1.585 ACTG1
actin, gamma 1
chr1_+_1971762 1.576 NM_002744
PRKCZ
protein kinase C, zeta
chr20_-_62052922 1.559 NM_001193379
UCKL1
uridine-cytidine kinase 1-like 1
chr7_-_149101227 1.557 NM_207336
ZNF467
zinc finger protein 467
chr16_+_84204424 1.554 NM_014615
KIAA0182
KIAA0182
chr20_+_29870836 1.530 NM_033118
MYLK2
myosin light chain kinase 2
chr19_+_55164668 1.521 SIGLEC16
sialic acid binding Ig-like lectin 16 (gene/pseudogene)
chr1_+_29086156 1.501 NM_001166005
NM_001166007
NM_004437
NM_203342
NM_203343
EPB41




erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)




chr1_+_29086206 1.501 EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr12_+_108690199 1.486 C12orf34
chromosome 12 open reading frame 34
chr8_-_143692814 1.485 NM_015193
ARC
activity-regulated cytoskeleton-associated protein
chr8_+_27238979 1.446 NM_173175
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr3_+_50204026 1.417 NM_000172
NM_144499
GNAT1

guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1

chr8_-_144882679 1.411 FAM83H
family with sequence similarity 83, member H
chr3_+_128190070 1.405 NM_032242
PLXNA1
plexin A1
chr1_+_46418786 1.402 TSPAN1
tetraspanin 1
chr1_+_16220952 1.391 NM_001042704
NM_004070
CLCNKA

CLCNKB
chloride channel Ka

chloride channel Kb
chr4_+_75529716 1.390 NM_001657
AREG
amphiregulin
chr19_+_18584666 1.387 NM_012109
TMEM59L
transmembrane protein 59-like
chr16_+_711139 1.379 NM_023933
FAM173A
family with sequence similarity 173, member A
chr1_-_54256390 1.360 NM_001010978
LDLRAD1
low density lipoprotein receptor class A domain containing 1
chr6_-_39398293 1.330 NM_001135105
NM_001135106
NM_001135107
NM_032115
KCNK16



potassium channel, subfamily K, member 16



chr16_+_29697090 1.321 ZG16
zymogen granule protein 16 homolog (rat)
chr22_+_21464980 1.321


chr16_+_67236730 1.311 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr11_+_73036241 1.296 NM_001130034
NM_001130035
PLEKHB1

pleckstrin homology domain containing, family B (evectins) member 1

chr9_-_138757175 1.292 NM_001001712
LCN10
lipocalin 10
chr7_-_1562272 1.269 NM_001097620
TMEM184A
transmembrane protein 184A
chr7_+_150321771 1.252 NM_001160109
NM_001160110
NM_001160111
NOS3


nitric oxide synthase 3 (endothelial cell)


chrX_+_110226030 1.250 NM_002578
PAK3
p21 protein (Cdc42/Rac)-activated kinase 3
chr1_+_22176004 1.242 NM_007352
CELA3A
CELA3B
chymotrypsin-like elastase family, member 3A
chymotrypsin-like elastase family, member 3B
chr19_+_7834124 1.241 EVI5L
ecotropic viral integration site 5-like
chr22_+_19660361 1.237 AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr17_-_23716391 1.218 NM_001080837
SEBOX
SEBOX homeobox
chr7_+_129807467 1.199 NM_001868
CPA1
carboxypeptidase A1 (pancreatic)
chr6_+_39124534 1.189 NM_002062
GLP1R
glucagon-like peptide 1 receptor
chr16_-_772926 1.182 NM_001025190
MSLNL
mesothelin-like
chr19_+_3457264 1.179 NM_016263
FZR1
fizzy/cell division cycle 20 related 1 (Drosophila)
chr17_-_77634455 1.176 FASN
fatty acid synthase
chr11_+_2422747 1.172 NM_000218
KCNQ1
potassium voltage-gated channel, KQT-like subfamily, member 1
chr16_-_11282595 1.161 NM_002761
PRM1
protamine 1
chr7_+_143683365 1.158 NM_005435
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr4_+_75699652 1.155 NM_001657
AREG
amphiregulin
chr3_+_42675841 1.147 ZBTB47
zinc finger and BTB domain containing 47
chr19_-_3930828 1.145 EEF2
eukaryotic translation elongation factor 2
chr15_+_81567327 1.140 NM_001144903
NM_023003
TM6SF1

transmembrane 6 superfamily member 1

chr11_+_70926718 1.138 NM_021046
KRTAP5-8
keratin associated protein 5-8
chrX_+_71047344 1.134 NM_001013627
NHSL2
NHS-like 2
chr10_+_71060008 1.121 NM_145306
C10orf35
chromosome 10 open reading frame 35
chr17_-_77469319 1.102 SIRT7
sirtuin 7
chr5_+_1254709 1.099 NM_001003841
SLC6A19
solute carrier family 6 (neutral amino acid transporter), member 19
chr6_+_43507466 1.092 NM_033450
ABCC10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr7_-_72822471 1.090 NM_001306
CLDN3
claudin 3
chr17_-_77469316 1.087 SIRT7
sirtuin 7
chrX_-_69186506 1.074 NM_001002254
AWAT2
acyl-CoA wax alcohol acyltransferase 2
chr17_-_77469327 1.073 NM_016538
SIRT7
sirtuin 7
chr5_-_525916 1.066 LOC25845
hypothetical LOC25845
chr1_+_24755152 1.065 NM_001010980
C1orf130
chromosome 1 open reading frame 130
chr13_+_112681626 1.064 NM_024979
MCF2L
MCF.2 cell line derived transforming sequence-like
chr22_-_17891777 1.054 CLDN5
claudin 5
chr1_+_2149993 1.054 NM_003036
SKI
v-ski sarcoma viral oncogene homolog (avian)
chr8_-_145609737 1.053 SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr9_+_139153409 1.052 NM_000832
NM_001185090
NM_001185091
NM_007327
NM_021569
GRIN1




glutamate receptor, ionotropic, N-methyl D-aspartate 1




chr17_+_24095135 1.049 NM_004295
TRAF4
TNF receptor-associated factor 4
chr16_-_790699 1.046 NM_016541
GNG13
guanine nucleotide binding protein (G protein), gamma 13
chr22_+_21852743 1.041 BCR
breakpoint cluster region
chr1_-_11841476 1.040 NM_002521
NPPB
natriuretic peptide B
chr1_-_204179169 1.034 NM_052934
NM_134325
SLC26A9

solute carrier family 26, member 9

chrX_-_48654178 1.033 NM_001042498
SLC35A2
solute carrier family 35 (UDP-galactose transporter), member A2
chr1_-_17318452 1.030 NM_007365
PADI2
peptidyl arginine deiminase, type II
chr11_-_2127368 1.022 NM_001007139
IGF2
insulin-like growth factor 2 (somatomedin A)
chr22_-_20235749 1.018 NM_001128633
RIMBP3C
RIMS binding protein 3C
chr22_+_18081968 1.017 NM_002688
SEPT5
septin 5
chr16_+_4325142 1.012 GLIS2
GLIS family zinc finger 2
chr11_+_61204392 1.010 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr10_+_46413551 1.009 NM_014696
GPRIN2
G protein regulated inducer of neurite outgrowth 2
chr17_+_26839143 1.006 RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr17_+_26060617 0.994


chr22_-_48793181 0.992 NM_001001694
IL17REL
interleukin 17 receptor E-like
chrX_+_70359780 0.992 NM_000166
GJB1
gap junction protein, beta 1, 32kDa
chr7_+_75947762 0.992 NM_001102596
DTX2
deltex homolog 2 (Drosophila)
chr19_-_59438411 0.989 NM_024318
LILRB3
LILRA6
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
chr1_-_3437834 0.989 MEGF6
multiple EGF-like-domains 6
chr11_+_64631919 0.985 C11orf2
chromosome 11 open reading frame 2
chr1_-_43509187 0.985 EBNA1BP2
EBNA1 binding protein 2
chr6_+_33697023 0.977 NM_002224
ITPR3
inositol 1,4,5-triphosphate receptor, type 3
chr17_-_77129802 0.972 NM_025161
C17orf70
chromosome 17 open reading frame 70
chr5_-_1165106 0.971 NM_006598
SLC12A7
solute carrier family 12 (potassium/chloride transporters), member 7
chr15_-_73818013 0.969


chr15_-_75694674 0.969 LINGO1
leucine rich repeat and Ig domain containing 1
chr6_+_43319199 0.965 NM_032538
TTBK1
tau tubulin kinase 1
chr1_-_1139358 0.964 NM_003327
TNFRSF4
tumor necrosis factor receptor superfamily, member 4
chr22_+_21340757 0.958


chr8_+_27238964 0.956 NM_173176
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr9_-_130980302 0.952 IER5L
immediate early response 5-like
chr15_-_38332401 0.948 NM_001039905
C15orf56
chromosome 15 open reading frame 56
chr9_+_132961683 0.946 NM_001185095
NM_001185096
NM_031426
AIF1L


allograft inflammatory factor 1-like


chr22_+_21384862 0.943 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr19_+_3490154 0.940 NM_001135580
C19orf71
chromosome 19 open reading frame 71
chr16_+_67236699 0.940 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr17_-_43390108 0.934 NM_024320
PRR15L
proline rich 15-like
chr22_+_19248733 0.931 MED15
mediator complex subunit 15
chr11_-_6600385 0.927 DCHS1
dachsous 1 (Drosophila)
chr1_-_55039458 0.927 NM_001114108
NM_017904
TTC22

tetratricopeptide repeat domain 22

chr12_+_111980044 0.927 NM_004416
DTX1
deltex homolog 1 (Drosophila)
chr7_-_130891861 0.919 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr11_+_56984702 0.917 NM_178570
RTN4RL2
reticulon 4 receptor-like 2
chr3_+_42679602 0.916 ZBTB47
zinc finger and BTB domain containing 47
chr9_-_139060416 0.915 NM_015392
NPDC1
neural proliferation, differentiation and control, 1
chr2_+_238712101 0.915 NM_198582
KLHL30
kelch-like 30 (Drosophila)
chr1_-_3517918 0.912 NM_001409
MEGF6
multiple EGF-like-domains 6
chr8_+_102574012 0.907 GRHL2
grainyhead-like 2 (Drosophila)
chr20_-_60375695 0.906 NM_005560
LAMA5
laminin, alpha 5
chr19_+_45799060 0.906 NM_001042545
LTBP4
latent transforming growth factor beta binding protein 4
chrX_-_48661226 0.903 NM_006875
PIM2
pim-2 oncogene
chr21_+_44818033 0.898 NM_198687
KRTAP10-4
keratin associated protein 10-4
chr1_+_1104939 0.896 NM_153254
TTLL10
tubulin tyrosine ligase-like family, member 10
chr22_+_21006814 0.896


chr19_-_51829778 0.896 NM_033258
GNG8
guanine nucleotide binding protein (G protein), gamma 8
chr3_+_129682434 0.895


chr9_-_139060285 0.885 NPDC1
neural proliferation, differentiation and control, 1
chr9_-_130980359 0.884 NM_203434
IER5L
immediate early response 5-like
chr11_+_183079 0.883 NM_145651
SCGB1C1
secretoglobin, family 1C, member 1
chr16_+_3002457 0.883 NM_020982
CLDN9
claudin 9
chr22_-_20235372 0.883 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr11_+_60448487 0.883 NM_017870
NM_178031
TMEM132A

transmembrane protein 132A

chr9_+_132961723 0.882 AIF1L
allograft inflammatory factor 1-like
chr19_-_2378530 0.877 TIMM13
translocase of inner mitochondrial membrane 13 homolog (yeast)
chr19_+_15765760 0.876 NM_001004466
OR10H5
olfactory receptor, family 10, subfamily H, member 5
chr9_+_135389698 0.876 NM_014694
ADAMTSL2
ADAMTS-like 2
chr19_-_7896974 0.874 NM_206833
CTXN1
cortexin 1
chr17_+_73676219 0.871 NM_004710
SYNGR2
synaptogyrin 2
chr22_-_17545872 0.869 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr11_+_61279436 0.869 NM_013279
C11orf9
chromosome 11 open reading frame 9
chr10_-_98470164 0.866 NM_152309
PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
chr19_-_54212158 0.859 NM_000894
LHB
luteinizing hormone beta polypeptide
chr7_-_131911808 0.857 NM_001105543
NM_020911
PLXNA4

plexin A4

chr19_+_51424848 0.856 NM_198541
IGFL1
IGF-like family member 1
chr1_+_226352179 0.854 ARF1
ADP-ribosylation factor 1
chr15_+_72687765 0.852 NM_003992
CLK3
CDC-like kinase 3
chr1_+_154478574 0.849 NM_199173
BGLAP
bone gamma-carboxyglutamate (gla) protein
chr1_+_18680010 0.845 NM_152375
KLHDC7A
kelch domain containing 7A
chr7_+_5598979 0.843 NM_003088
FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr17_+_18221803 0.833 NM_001145127
EVPLL
envoplakin-like
chr17_-_77469280 0.832 SIRT7
sirtuin 7
chr11_+_1607580 0.831 NM_001001480
KRTAP5-5
keratin associated protein 5-5
chr17_+_4434582 0.830 NM_001114974
SMTNL2
smoothelin-like 2
chr14_+_104117100 0.825 NM_001008404
C14orf180
chromosome 14 open reading frame 180
chr1_-_2451543 0.823 NM_001010926
HES5
hairy and enhancer of split 5 (Drosophila)
chr9_+_123544884 0.820 NM_138709
DAB2IP
DAB2 interacting protein
chr1_+_41057186 0.819 KCNQ4
potassium voltage-gated channel, KQT-like subfamily, member 4
chr21_+_44530148 0.817 NM_000383
AIRE
autoimmune regulator
chr8_-_41641881 0.814 NM_001142445
NM_020478
NM_020480
ANK1


ankyrin 1, erythrocytic


chr18_+_19706979 0.814 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr17_+_7225088 0.814 NM_003985
TNK1
tyrosine kinase, non-receptor, 1
chr1_-_19058741 0.812 NM_152232
TAS1R2
taste receptor, type 1, member 2
chr16_-_87460514 0.812 NM_001080487
PABPN1L
poly(A) binding protein, nuclear 1-like (cytoplasmic)
chr1_-_2486313 0.811 NM_003820
TNFRSF14
tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
chr22_+_20350272 0.808 NM_014337
NM_148175
NM_148176
PPIL2


peptidylprolyl isomerase (cyclophilin)-like 2


chr10_+_43187095 0.807 NM_001184963
NM_173160
FXYD4

FXYD domain containing ion transport regulator 4

chr1_+_31855873 0.801 NM_001525
HCRTR1
hypocretin (orexin) receptor 1
chr22_+_17847467 0.800 CDC45
cell division cycle 45 homolog (S. cerevisiae)
chr19_+_1236766 0.800 NM_001405
EFNA2
ephrin-A2
chr19_+_41039649 0.799 NM_032123
NM_199179
NM_199180
KIRREL2


kin of IRRE like 2 (Drosophila)


chr22_+_18124225 0.798 NM_005992
NM_080646
NM_080647
TBX1


T-box 1


chr1_+_95355415 0.798 NM_152487
TMEM56
transmembrane protein 56
chr9_-_139060377 0.788 NPDC1
neural proliferation, differentiation and control, 1
chr8_+_22493928 0.787 NM_176871
NM_198042
PDLIM2

PDZ and LIM domain 2 (mystique)

chr22_-_20314366 0.786 YDJC
YdjC homolog (bacterial)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.14 1.80e-04 GO:0007275 multicellular organismal development
1.13 2.01e-04 GO:0023052 signaling
1.20 9.62e-04 GO:0007166 cell surface receptor linked signaling pathway
1.13 1.21e-03 GO:0007165 signal transduction
1.12 1.91e-03 GO:0032502 developmental process
1.13 8.13e-03 GO:0048856 anatomical structure development
1.07 1.77e-02 GO:0065007 biological regulation
1.13 2.89e-02 GO:0048731 system development
1.07 3.06e-02 GO:0050794 regulation of cellular process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.21 2.68e-07 GO:0044459 plasma membrane part
1.21 1.09e-03 GO:0031226 intrinsic to plasma membrane
1.21 2.14e-03 GO:0005887 integral to plasma membrane
1.57 3.31e-03 GO:0016324 apical plasma membrane
1.14 1.47e-02 GO:0005576 extracellular region
1.43 2.97e-02 GO:0016323 basolateral plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.23 3.53e-03 GO:0005102 receptor binding