Motif ID: SOX17.p2

Z-value: 1.336


Transcription factors associated with SOX17.p2:

Gene SymbolEntrez IDGene Name
SOX17 64321 SRY (sex determining region Y)-box 17



Activity profile for motif SOX17.p2.

activity profile for motif SOX17.p2


Sorted Z-values histogram for motif SOX17.p2

Sorted Z-values for motif SOX17.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX17.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_207668787 2.057 NM_001104548
LOC642587
NPC-A-5
chr5_+_177564140 1.910 HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr5_+_177564139 1.672 HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr5_+_177564102 1.569 NM_004499
NM_031266
HNRNPAB

heterogeneous nuclear ribonucleoprotein A/B

chr2_+_232281491 1.464 PTMA
prothymosin, alpha
chr1_-_204179169 1.319 NM_052934
NM_134325
SLC26A9

solute carrier family 26, member 9

chr2_+_232281470 1.275 NM_001099285
NM_002823
PTMA

prothymosin, alpha

chr3_-_48576204 1.236 NM_033199
UCN2
urocortin 2
chrX_+_77889861 1.170 NM_005296
LPAR4
lysophosphatidic acid receptor 4
chr21_+_33320080 1.134 NM_005806
OLIG2
oligodendrocyte lineage transcription factor 2
chrX_-_24600661 1.131 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr19_+_40958206 1.080 NM_001172630
NM_052948
ARHGAP33

Rho GTPase activating protein 33

chr1_+_226404037 1.021 NM_020435
GJC2
gap junction protein, gamma 2, 47kDa
chr16_-_65774904 1.019 KIAA0895L
KIAA0895-like
chr11_-_16380967 1.012 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr15_+_29406335 1.007 NM_015995
KLF13
Kruppel-like factor 13
chr11_-_66877519 1.006 NM_021173
POLD4
polymerase (DNA-directed), delta 4
chr4_-_2233504 0.976 NM_006454
MXD4
MAX dimerization protein 4
chr19_+_748444 0.951 PTBP1
polypyrimidine tract binding protein 1
chr19_+_748448 0.943 PTBP1
polypyrimidine tract binding protein 1
chr9_+_136358145 0.929 RXRA
retinoid X receptor, alpha
chr5_+_148186348 0.914 NM_000024
ADRB2
adrenergic, beta-2-, receptor, surface
chr9_-_132759045 0.910 NM_198180
QRFP
pyroglutamylated RFamide peptide
chrX_-_10605726 0.894 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chrX_+_41078787 0.891 DDX3X
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked
chr9_+_136358134 0.889 NM_002957
RXRA
retinoid X receptor, alpha
chr4_-_2233606 0.886 MXD4
MAX dimerization protein 4
chr15_-_70277163 0.863 NM_001012642
GRAMD2
GRAM domain containing 2
chr11_+_35154775 0.851 CD44
CD44 molecule (Indian blood group)
chr13_-_107317460 0.830 NM_001080396
FAM155A
family with sequence similarity 155, member A
chr14_-_105623358 0.807 IGHA1
IGHD
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
chr12_-_6535481 0.794 NM_001039670
NM_001193457
NM_080730
IFFO1


intermediate filament family orphan 1


chr5_+_176807931 0.785 NM_001174102
PRR7
proline rich 7 (synaptic)
chr10_-_32707549 0.773 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr9_+_139255559 0.762 TUBB2C
tubulin, beta 2C
chr10_+_46413551 0.750 NM_014696
GPRIN2
G protein regulated inducer of neurite outgrowth 2
chr11_+_113280727 0.748 NM_006028
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chr9_+_139255519 0.745 NM_006088
TUBB2C
tubulin, beta 2C
chr11_-_20138445 0.721 NM_001029865
DBX1
developing brain homeobox 1
chr17_-_8054587 0.721 NM_004217
AURKB
aurora kinase B
chr6_+_50789215 0.714 NM_172238
TFAP2D
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr6_+_33047952 0.712 BRD2
bromodomain containing 2
chr9_+_139255563 0.710 TUBB2C
tubulin, beta 2C
chr1_+_1104939 0.707 NM_153254
TTLL10
tubulin tyrosine ligase-like family, member 10
chr16_+_580173 0.704 NM_021168
RAB40C
RAB40C, member RAS oncogene family
chr3_-_46879883 0.699 NM_000258
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr17_-_71648965 0.698 NM_001454
FOXJ1
forkhead box J1
chr7_+_116447499 0.690 ST7
suppression of tumorigenicity 7
chr11_+_60448487 0.672 NM_017870
NM_178031
TMEM132A

transmembrane protein 132A

chr3_+_128190070 0.664 NM_032242
PLXNA1
plexin A1
chr16_+_580057 0.662 NM_001172665
NM_001172666
RAB40C

RAB40C, member RAS oncogene family

chr19_+_748452 0.662 PTBP1
polypyrimidine tract binding protein 1
chr19_+_13090101 0.659 NM_052876
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chrX_+_41078353 0.655 DDX3X
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked
chr17_-_1478293 0.651 SLC43A2
solute carrier family 43, member 2
chr4_+_154345039 0.650 NM_015271
TRIM2
tripartite motif containing 2
chr21_-_35153664 0.648 RUNX1
runt-related transcription factor 1
chr1_+_23990228 0.648 NM_007260
LYPLA2
lysophospholipase II
chr4_+_75529716 0.645 NM_001657
AREG
amphiregulin
chr1_+_201541269 0.643 NM_006763
BTG2
BTG family, member 2
chr19_+_1401117 0.640 NM_005883
APC2
adenomatosis polyposis coli 2
chr16_+_580092 0.633 RAB40C
RAB40C, member RAS oncogene family
chr1_+_1971762 0.607 NM_002744
PRKCZ
protein kinase C, zeta
chr22_-_17892859 0.606 NM_001130861
NM_003277
CLDN5

claudin 5

chr19_+_748390 0.606 NM_002819
NM_031990
NM_031991
NM_175847
PTBP1



polypyrimidine tract binding protein 1



chr21_+_33364316 0.601 NM_138983
OLIG1
oligodendrocyte transcription factor 1
chr20_-_61933012 0.598 ZBTB46
zinc finger and BTB domain containing 46
chr7_+_148613304 0.594 LOC155060
AI894139 pseudogene
chr1_+_1256585 0.583 NM_152228
TAS1R3
taste receptor, type 1, member 3
chr17_-_45617899 0.576 COL1A1
collagen, type I, alpha 1
chr15_-_53822468 0.573 NM_173814
PRTG
protogenin
chr19_+_60543032 0.570 NM_032701
SUV420H2
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr19_+_11510578 0.570 NM_001299
CNN1
calponin 1, basic, smooth muscle
chr17_-_71747867 0.568 NM_052916
RNF157
ring finger protein 157
chr19_+_59333232 0.563 NM_014516
CNOT3
CCR4-NOT transcription complex, subunit 3
chr12_-_98072602 0.561 NM_020140
NM_181670
ANKS1B

ankyrin repeat and sterile alpha motif domain containing 1B

chr7_+_116447527 0.561 ST7
suppression of tumorigenicity 7
chr1_+_201541241 0.560 BTG2
BTG family, member 2
chr8_+_1759502 0.560 NM_014629
ARHGEF10
Rho guanine nucleotide exchange factor (GEF) 10
chr1_+_154855709 0.553 NM_021817
HAPLN2
hyaluronan and proteoglycan link protein 2
chr22_+_20316968 0.553 NM_152612
CCDC116
coiled-coil domain containing 116
chr1_+_110683580 0.546 RBM15
RNA binding motif protein 15
chr7_-_27171673 0.539 NM_152739
HOXA9
homeobox A9
chr6_+_25862905 0.534 NM_005495
SLC17A4
solute carrier family 17 (sodium phosphate), member 4
chr17_+_7125702 0.531 NM_001042
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
chr3_-_187309442 0.530 NM_004454
ETV5
ets variant 5
chr1_+_203463654 0.528 NM_014858
TMCC2
transmembrane and coiled-coil domain family 2
chr19_+_1401208 0.527 APC2
adenomatosis polyposis coli 2
chr19_+_59333287 0.523 CNOT3
CCR4-NOT transcription complex, subunit 3
chr1_-_50661716 0.520 NM_032110
DMRTA2
DMRT-like family A2
chr11_+_823007 0.520 CD151
CD151 molecule (Raph blood group)
chr12_+_6517600 0.519


chr1_+_32485404 0.515 NM_032648
FAM167B
family with sequence similarity 167, member B
chr17_+_72376022 0.515 NM_144677
MGAT5B
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
chr6_+_43319199 0.514 NM_032538
TTBK1
tau tubulin kinase 1
chr4_+_75699652 0.509 NM_001657
AREG
amphiregulin
chr10_-_134449467 0.506 NM_177400
NKX6-2
NK6 homeobox 2
chr3_-_12916547 0.504 IQSEC1
IQ motif and Sec7 domain 1
chr1_+_148089251 0.503 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr19_+_750281 0.502 PTBP1
polypyrimidine tract binding protein 1
chr17_-_77092569 0.500 ACTG1
actin, gamma 1
chr16_-_65775326 0.498 NM_001040715
KIAA0895L
KIAA0895-like
chr1_+_110683586 0.496 RBM15
RNA binding motif protein 15
chrX_+_67965517 0.496 NM_004429
EFNB1
ephrin-B1
chr13_-_29938029 0.495 NM_002128
HMGB1
high-mobility group box 1
chr12_+_47658502 0.492 NM_005430
WNT1
wingless-type MMTV integration site family, member 1
chr1_+_116455898 0.491 NM_152367
MAB21L3
mab-21-like 3 (C. elegans)
chr21_-_36870736 0.489 NM_001146077
CLDN14
claudin 14
chr21_+_33364420 0.488 OLIG1
oligodendrocyte transcription factor 1
chr12_-_94914133 0.487 NM_002108
HAL
histidine ammonia-lyase
chr3_-_51976428 0.486 NM_020418
NM_001174100
NM_033008
PCBP4


poly(rC) binding protein 4


chr16_-_11282595 0.485 NM_002761
PRM1
protamine 1
chr19_-_10352172 0.483 TYK2
tyrosine kinase 2
chr10_-_13430195 0.482 NM_001195602
NM_001195604
NM_012247
SEPHS1


selenophosphate synthetase 1


chr11_+_822965 0.479 CD151
CD151 molecule (Raph blood group)
chr16_-_30274182 0.478 NM_006110
CD2BP2
CD2 (cytoplasmic tail) binding protein 2
chr1_-_51560469 0.477 NM_001080494
TTC39A
tetratricopeptide repeat domain 39A
chr17_+_72883759 0.475 NM_001113494
SEPT9
septin 9
chr17_-_7996409 0.472 NM_002616
PER1
period homolog 1 (Drosophila)
chr16_-_2201011 0.471 NM_182563
C16orf79
chromosome 16 open reading frame 79
chr19_+_53819460 0.468 SPHK2
sphingosine kinase 2
chr15_+_76171981 0.465 NM_001101404
SH2D7
SH2 domain containing 7
chrX_+_99726445 0.465 NM_022144
TNMD
tenomodulin
chr17_+_45598363 0.460 NM_000023
NM_001135697
SGCA

sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)

chr11_-_71501385 0.459 NM_014042
C11orf51
chromosome 11 open reading frame 51
chr11_+_18676857 0.458 TMEM86A
transmembrane protein 86A
chr10_+_73703682 0.457 NM_019058
DDIT4
DNA-damage-inducible transcript 4
chr17_+_45617676 0.457


chr1_+_43597185 0.454 NM_001255
CDC20
cell division cycle 20 homolog (S. cerevisiae)
chr5_+_54434230 0.453 NM_006144
GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr1_+_110683467 0.452 NM_022768
RBM15
RNA binding motif protein 15
chr15_+_72687765 0.452 NM_003992
CLK3
CDC-like kinase 3
chr1_+_175406685 0.451 FAM5B
family with sequence similarity 5, member B
chr11_-_780065 0.449 CEND1
cell cycle exit and neuronal differentiation 1
chr11_+_17697685 0.448 NM_002478
MYOD1
myogenic differentiation 1
chr5_+_148717762 0.448 NM_024028
PCYOX1L
prenylcysteine oxidase 1 like
chr15_-_38188333 0.446 NM_001003940
BMF
Bcl2 modifying factor
chr17_-_39632845 0.445 ATXN7L3
ataxin 7-like 3
chr1_+_11674365 0.445 NM_198545
C1orf187
chromosome 1 open reading frame 187
chr16_+_67697622 0.444 NM_138612
HAS3
hyaluronan synthase 3
chr5_+_170668892 0.443 NM_021025
TLX3
T-cell leukemia homeobox 3
chr6_-_31890765 0.443 NM_005527
HSPA1L
heat shock 70kDa protein 1-like
chr11_+_822909 0.443 NM_001039490
NM_004357
NM_139029
NM_139030
CD151



CD151 molecule (Raph blood group)



chr22_+_17498320 0.442 NM_053006
TSSK2
testis-specific serine kinase 2
chr2_-_128138435 0.441 NM_017980
LIMS2
LIM and senescent cell antigen-like domains 2
chr12_+_105501161 0.441 NM_213594
RFX4
regulatory factor X, 4 (influences HLA class II expression)
chrX_+_41077594 0.440 NM_001193416
NM_001193417
NM_001356
DDX3X


DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked


chr7_-_27171648 0.440 HOXA9
homeobox A9
chr1_-_155095289 0.437 NM_014215
INSRR
insulin receptor-related receptor
chr6_+_30796064 0.436 TUBB
tubulin, beta
chr15_+_37660568 0.436 NM_003246
THBS1
thrombospondin 1
chr17_+_77574476 0.431 NM_144999
LRRC45
leucine rich repeat containing 45
chr1_-_23543330 0.430 NM_001102397
NM_001102398
NM_001102399
NM_005826
HNRNPR



heterogeneous nuclear ribonucleoprotein R



chr16_-_30274064 0.428 CD2BP2
CD2 (cytoplasmic tail) binding protein 2
chr16_-_28425632 0.428 NM_145659
IL27
interleukin 27
chr1_+_148125090 0.426 NM_003517
HIST2H2AC
histone cluster 2, H2ac
chr5_-_131854325 0.425 NM_002198
IRF1
interferon regulatory factor 1
chr13_-_98428244 0.424 NM_001130048
NM_001130050
DOCK9

dedicator of cytokinesis 9

chr11_-_65813031 0.423 YIF1A
Yip1 interacting factor homolog A (S. cerevisiae)
chr11_+_18676913 0.423 NM_153347
TMEM86A
transmembrane protein 86A
chr17_-_59131210 0.422 NM_030576
LIMD2
LIM domain containing 2
chr1_+_148090804 0.420 NM_021059
NM_001005464
HIST2H3C
HIST2H3A
histone cluster 2, H3c
histone cluster 2, H3a
chrX_+_106030049 0.418 NM_001171092
CLDN2
claudin 2
chr22_+_38246509 0.414 NM_001675
NM_182810
ATF4

activating transcription factor 4 (tax-responsive enhancer element B67)

chr17_+_77528782 0.413 ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr1_-_41259973 0.412 NM_001168247
NM_144990
SLFNL1

schlafen-like 1

chr9_-_138778780 0.409 NM_203347
LCN15
lipocalin 15
chr19_-_6230927 0.408 NM_005934
MLLT1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr1_+_154386358 0.407 NM_001193301
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr7_+_123036312 0.404 NM_080928
ASB15
ankyrin repeat and SOCS box containing 15
chr15_-_100280784 0.404 NM_001004195
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chr13_-_29937966 0.402 HMGB1
HMGB1P6
high-mobility group box 1
high-mobility group box 1 pseudogene 6
chr17_-_77573974 0.402 NM_144998
STRA13
stimulated by retinoic acid 13 homolog (mouse)
chr22_+_36632242 0.399 NM_033386
MICALL1
MICAL-like 1
chr10_+_114033403 0.397 NM_058222
TECTB
tectorin beta
chr1_+_196153122 0.396 NM_020204
LHX9
LIM homeobox 9
chr7_+_134114957 0.394 CALD1
caldesmon 1
chr9_+_134843918 0.393 NM_001135031
NM_004188
GFI1B

growth factor independent 1B transcription repressor

chr12_+_105500814 0.391 RFX4
regulatory factor X, 4 (influences HLA class II expression)
chr19_+_2115119 0.390 NM_032482
DOT1L
DOT1-like, histone H3 methyltransferase (S. cerevisiae)
chr19_+_47593137 0.390


chr4_-_41445479 0.386 PHOX2B
paired-like homeobox 2b
chr9_+_91409746 0.385 NM_006705
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr20_-_538909 0.385 NM_004609
TCF15
transcription factor 15 (basic helix-loop-helix)
chr3_-_58175437 0.384 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr6_-_110843432 0.383 NM_003649
NM_004032
DDO

D-aspartate oxidase

chr19_-_3930828 0.383 EEF2
eukaryotic translation elongation factor 2
chr11_-_63440891 0.382 NM_173587
RCOR2
REST corepressor 2
chr9_-_139084833 0.381 NM_178448
C9orf140
chromosome 9 open reading frame 140
chr17_+_7416780 0.381 NM_001416
EIF4A1
eukaryotic translation initiation factor 4A1
chr12_-_49076658 0.381 NM_001145475
FAM186A
family with sequence similarity 186, member A
chr11_-_59139755 0.380 OSBP
oxysterol binding protein
chr17_+_77529070 0.376 ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr12_-_67012303 0.376 NM_017440
NM_020128
MDM1

Mdm1 nuclear protein homolog (mouse)

chr22_-_17512097 0.376 DGCR14
DiGeorge syndrome critical region gene 14
chr2_-_73151894 0.373 SFXN5
sideroflexin 5
chr1_-_226679648 0.371 NM_003493
HIST3H3
histone cluster 3, H3
chr22_-_17512174 0.370 NM_022719
DGCR14
DiGeorge syndrome critical region gene 14
chr11_+_20577521 0.368 NM_004211
SLC6A5
solute carrier family 6 (neurotransmitter transporter, glycine), member 5
chr1_-_16033866 0.368



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.24 8.04e-05 GO:0007275 multicellular organismal development
1.23 9.37e-05 GO:0032502 developmental process
1.18 1.31e-04 GO:0032501 multicellular organismal process
1.38 4.07e-04 GO:0007399 nervous system development
1.24 7.04e-04 GO:0048856 anatomical structure development
1.25 1.42e-03 GO:0048731 system development
1.84 4.02e-03 GO:0030029 actin filament-based process
1.60 9.42e-03 GO:0007417 central nervous system development
1.27 3.95e-02 GO:0048513 organ development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.72 5.09e-03 GO:0000786 nucleosome
1.13 8.58e-03 GO:0005634 nucleus

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.53 9.92e-07 GO:0030528 transcription regulator activity
1.41 2.04e-03 GO:0001071 nucleic acid binding transcription factor activity
1.41 2.04e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.25 2.44e-03 GO:0003677 DNA binding
1.68 1.21e-02 GO:0003779 actin binding
1.17 4.06e-02 GO:0003676 nucleic acid binding