Motif ID: SREBF1,2.p2

Z-value: 1.264


Transcription factors associated with SREBF1,2.p2:

Gene SymbolEntrez IDGene Name
SREBF1 6720 sterol regulatory element binding transcription factor 1
SREBF2 6721 sterol regulatory element binding transcription factor 2



Activity profile for motif SREBF1,2.p2.

activity profile for motif SREBF1,2.p2


Sorted Z-values histogram for motif SREBF1,2.p2

Sorted Z-values for motif SREBF1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SREBF1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_10625449 3.727 LOC147727
hypothetical LOC147727
chr19_+_10625987 3.487 ILF3
interleukin enhancer binding factor 3, 90kDa
chr19_+_10625896 3.262 NM_001137673
NM_004516
NM_012218
NM_017620
NM_153464
ILF3




interleukin enhancer binding factor 3, 90kDa




chr19_+_10626106 3.050 ILF3
interleukin enhancer binding factor 3, 90kDa
chr20_+_39199542 1.573 NM_002660
NM_182811
PLCG1

phospholipase C, gamma 1

chr19_+_748390 1.496 NM_002819
NM_031990
NM_031991
NM_175847
PTBP1



polypyrimidine tract binding protein 1



chr19_+_748444 1.492 PTBP1
polypyrimidine tract binding protein 1
chr20_-_39199936 1.441


chr7_+_882704 1.407 NM_015949
GET4
golgi to ER traffic protein 4 homolog (S. cerevisiae)
chr17_-_7078399 1.345 DVL2
dishevelled, dsh homolog 2 (Drosophila)
chr17_-_7078304 1.293 DVL2
dishevelled, dsh homolog 2 (Drosophila)
chr17_-_7078446 1.266 NM_004422
DVL2
dishevelled, dsh homolog 2 (Drosophila)
chr19_+_3958690 1.262 NM_015897
PIAS4
protein inhibitor of activated STAT, 4
chr7_+_882766 1.259 GET4
golgi to ER traffic protein 4 homolog (S. cerevisiae)
chr10_+_5478521 1.209 NM_005863
NET1
neuroepithelial cell transforming 1
chr10_-_14090459 1.199 FRMD4A
FERM domain containing 4A
chr20_+_43953428 1.101 CTSA
cathepsin A
chr20_+_43953606 1.101 CTSA
cathepsin A
chr17_+_75851984 1.098


chr7_+_149696792 1.044 NM_001099695
NM_001099696
NM_013400
REPIN1


replication initiator 1


chr12_-_56432375 1.036 CDK4
cyclin-dependent kinase 4
chr12_+_52713098 1.033 NM_018953
HOXC5
homeobox C5
chr17_+_77478858 1.031 LOC92659
hypothetical LOC92659
chr12_-_56432377 0.998 CDK4
cyclin-dependent kinase 4
chr12_-_56432292 0.988 CDK4
cyclin-dependent kinase 4
chr17_-_77478835 0.966 NM_002359
MAFG
v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr12_-_56432385 0.966 NM_000075
CDK4
cyclin-dependent kinase 4
chr19_+_54682661 0.958 RPL13A
ribosomal protein L13a
chr1_+_44213200 0.957 ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr3_+_4996096 0.950 NM_003670
BHLHE40
basic helix-loop-helix family, member e40
chr6_-_169392771 0.941


chr17_+_39778016 0.939 NM_002087
GRN
granulin
chr22_+_34107087 0.936 HMOX1
heme oxygenase (decycling) 1
chr2_-_172675873 0.930 DLX2
distal-less homeobox 2
chr17_+_75689985 0.927 GAA
glucosidase, alpha; acid
chr6_+_160310118 0.907 NM_000876
IGF2R
insulin-like growth factor 2 receptor
chr1_+_44213210 0.893 ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr1_+_44213229 0.891 ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr11_+_66915997 0.887 NM_004584
RAD9A
RAD9 homolog A (S. pombe)
chr1_+_17121012 0.880 NM_014675
CROCC
ciliary rootlet coiled-coil, rootletin
chr6_-_33822659 0.871 NM_001142883
NM_054111
IP6K3

inositol hexakisphosphate kinase 3

chr9_-_37894098 0.866 MCART1
mitochondrial carrier triple repeat 1
chr19_+_45948598 0.862 NM_004596
SNRPA
small nuclear ribonucleoprotein polypeptide A
chr12_+_54396099 0.857 BLOC1S1-RDH5
BLOC1S1
BLOC1S1-RDH5 read-through transcript
biogenesis of lysosomal organelles complex-1, subunit 1
chr1_+_44213260 0.854 ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr1_+_44213182 0.845 NM_001039457
NM_004047
ATP6V0B

ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b

chr20_+_43953331 0.842 CTSA
cathepsin A
chr12_+_112280753 0.831 NM_001159727
NM_173542
PLBD2

phospholipase B domain containing 2

chr17_+_18159333 0.811 SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr3_+_51403760 0.811 NM_013286
RBM15B
RNA binding motif protein 15B
chr12_+_54396086 0.810 NM_001487
BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chr1_-_28432060 0.808 DNAJC8
DnaJ (Hsp40) homolog, subfamily C, member 8
chr9_-_137531517 0.798 NM_001048265
NM_144654
C9orf116

chromosome 9 open reading frame 116

chr20_+_43953372 0.792 CTSA
cathepsin A
chr6_+_30796064 0.785 TUBB
tubulin, beta
chr8_+_67201684 0.781 NM_033058
NM_184085
NM_184086
NM_184087
TRIM55



tripartite motif containing 55



chr17_+_75689894 0.781 NM_000152
NM_001079803
NM_001079804
GAA


glucosidase, alpha; acid


chr3_-_11585264 0.777 NM_001128221
VGLL4
vestigial like 4 (Drosophila)
chr19_+_748452 0.776 PTBP1
polypyrimidine tract binding protein 1
chr16_-_4837266 0.775 NM_032569
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr16_-_5023934 0.768 NM_016256
NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr7_+_149696901 0.759 REPIN1
replication initiator 1
chr1_+_109963982 0.758 AMPD2
adenosine monophosphate deaminase 2
chr16_-_5023914 0.744 NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr3_+_4996141 0.740 BHLHE40
basic helix-loop-helix family, member e40
chr6_+_33045070 0.738


chr1_-_28432095 0.737 NM_014280
DNAJC8
DnaJ (Hsp40) homolog, subfamily C, member 8
chr17_+_75689955 0.734 GAA
glucosidase, alpha; acid
chr8_+_142501188 0.732 NM_007079
NM_032611
PTP4A3

protein tyrosine phosphatase type IVA, member 3

chr12_+_54396118 0.732 BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chr19_+_748448 0.731 PTBP1
polypyrimidine tract binding protein 1
chr10_+_45542653 0.727 NM_001169106
NM_001169107
NM_015262
FAM21C


FAM21A
family with sequence similarity 21, member C


family with sequence similarity 21, member A
chr19_+_54682676 0.724 NM_012423
RPL13A
ribosomal protein L13a
chr1_+_29011240 0.716 NM_000911
OPRD1
opioid receptor, delta 1
chr1_-_153195188 0.713 NM_020524
PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
chr8_+_98857190 0.711 LAPTM4B
lysosomal protein transmembrane 4 beta
chr2_-_238164042 0.710 RAB17
RAB17, member RAS oncogene family
chr17_+_18159330 0.699 SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr7_-_27162688 0.697 NM_006896
HOXA7
homeobox A7
chr17_+_18159294 0.692 NM_144775
SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr3_+_185515013 0.689 EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr9_+_131428272 0.684 METTL11A
methyltransferase like 11A
chr17_-_77092569 0.683 ACTG1
actin, gamma 1
chr17_+_39778191 0.682 GRN
granulin
chr13_+_112999538 0.681 LAMP1
lysosomal-associated membrane protein 1
chr17_+_39778153 0.676 GRN
granulin
chr17_+_39778180 0.674 GRN
granulin
chr7_-_100595552 0.674 NM_003378
VGF
VGF nerve growth factor inducible
chr22_+_34107051 0.671 NM_002133
HMOX1
heme oxygenase (decycling) 1
chr3_+_51992339 0.667 NM_000666
NM_001198895
NM_001198896
NM_001198897
NM_001198898
ACY1




aminoacylase 1




chr1_-_202595666 0.665 NM_014935
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr6_+_30796123 0.663 NM_178014
TUBB
tubulin, beta
chr15_+_41871768 0.663 NM_001018108
SERF2
small EDRK-rich factor 2
chr12_+_52680143 0.662 NM_006897
HOXC9
homeobox C9
chr19_-_60587414 0.661 NM_001190764
LOC388564
hypothetical protein LOC388564
chr9_+_696744 0.660 NM_153186
KANK1
KN motif and ankyrin repeat domains 1
chr1_+_109963950 0.659 NM_139156
AMPD2
adenosine monophosphate deaminase 2
chr5_+_149845503 0.655 NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr16_+_2503978 0.652 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr16_+_2503915 0.647 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr16_+_2503994 0.641 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr16_+_5023672 0.640 LOC100507589
hypothetical LOC100507589
chr2_+_108571336 0.639 NM_001193488
LIMS1
LIM and senescent cell antigen-like domains 1
chr6_+_30796121 0.636 TUBB
tubulin, beta
chr6_+_41622111 0.636 NM_001012426
NM_001012427
NM_138457
FOXP4


forkhead box P4


chr1_+_224337937 0.635


chr2_+_108571209 0.634 LIMS1
LIM and senescent cell antigen-like domains 1
chr9_+_131428225 0.626 NM_014064
METTL11A
methyltransferase like 11A
chr9_+_114953048 0.623 NM_001860
SLC31A2
solute carrier family 31 (copper transporters), member 2
chr9_+_114953087 0.622 SLC31A2
solute carrier family 31 (copper transporters), member 2
chr6_-_31938530 0.617 NEU1
sialidase 1 (lysosomal sialidase)
chr16_+_2503676 0.617 NM_001198569
NM_001694
ATP6V0C

ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c

chr1_+_149221122 0.617 NM_003568
ANXA9
annexin A9
chr15_+_73415426 0.616 NM_017828
COMMD4
COMM domain containing 4
chr3_+_185515108 0.612 EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr20_-_43953036 0.609 NM_080749
NEURL2
neuralized homolog 2 (Drosophila)
chr6_+_33044353 0.609


chr6_+_33044378 0.600 NM_005104
BRD2
bromodomain containing 2
chr20_+_33823318 0.598 NM_016436
PHF20
PHD finger protein 20
chr16_-_5023562 0.591 NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr22_+_38903825 0.590 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr6_+_151815114 0.586 NM_024573
C6orf211
chromosome 6 open reading frame 211
chr2_+_108571177 0.583 NM_004987
LIMS1
LIM and senescent cell antigen-like domains 1
chr3_+_4996305 0.581 BHLHE40
basic helix-loop-helix family, member e40
chr8_+_98856984 0.578 NM_018407
LAPTM4B
lysosomal protein transmembrane 4 beta
chr16_+_11669736 0.576 NM_003498
SNN
stannin
chr17_-_44043361 0.574 NM_004502
HOXB7
homeobox B7
chr20_-_60484420 0.566 NM_080473
GATA5
GATA binding protein 5
chr19_-_13088212 0.564 NM_001142554
NM_017722
NM_001136035
TRMT1


TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae)


chr20_-_61317891 0.557 NM_017798
YTHDF1
YTH domain family, member 1
chr15_+_41871809 0.553 SERF2-C15ORF63
SERF2
SERF2-C15orf63 read-through transcript
small EDRK-rich factor 2
chr16_+_2504001 0.550 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr16_+_22124870 0.542 NM_013302
EEF2K
eukaryotic elongation factor-2 kinase
chr4_+_17225344 0.541 NM_025205
MED28
mediator complex subunit 28
chr17_-_44043278 0.537 HOXB7
homeobox B7
chr13_+_112999590 0.528 LAMP1
lysosomal-associated membrane protein 1
chr16_+_66676833 0.519 NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr17_-_18158928 0.518 NM_004618
TOP3A
topoisomerase (DNA) III alpha
chr16_+_66676851 0.517 NM_004555
NM_173163
NM_173164
NM_173165
NFATC3



nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3



chr16_-_66072477 0.517 NM_004691
ATP6V0D1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr12_-_9913199 0.516 CLEC2B
C-type lectin domain family 2, member B
chr5_+_244625 0.515 NM_001080478
LRRC14B
leucine rich repeat containing 14B
chr14_-_93919305 0.515 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr10_+_101532450 0.514 NM_000392
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr1_+_11788827 0.512 CLCN6
chloride channel 6
chr20_+_43028533 0.512 NM_006282
STK4
serine/threonine kinase 4
chr10_+_18988282 0.509 NM_178815
ARL5B
ADP-ribosylation factor-like 5B
chr7_-_1562272 0.506 NM_001097620
TMEM184A
transmembrane protein 184A
chr8_+_142471290 0.505


chr17_+_22645232 0.503 NM_015626
NM_134265
WSB1

WD repeat and SOCS box containing 1

chr15_-_48766018 0.502 TRPM7
transient receptor potential cation channel, subfamily M, member 7
chr7_+_142723340 0.500 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr19_-_45546250 0.497 C19orf47
chromosome 19 open reading frame 47
chr1_+_110683580 0.497 RBM15
RNA binding motif protein 15
chr16_-_71549149 0.496 ZFHX3
zinc finger homeobox 3
chr1_+_3360880 0.496 NM_014448
ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr6_-_33493640 0.495 CUTA
cutA divalent cation tolerance homolog (E. coli)
chr9_-_133574928 0.493 NM_198679
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr1_+_110683586 0.492 RBM15
RNA binding motif protein 15
chr2_+_26840626 0.490 NM_017877
CENPA
C2orf18
centromere protein A
chromosome 2 open reading frame 18
chr10_+_101532544 0.487 ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr22_+_21318779 0.485 NM_199127
GGTLC2
gamma-glutamyltransferase light chain 2
chr8_-_143482433 0.481 NM_145003
TSNARE1
t-SNARE domain containing 1
chr1_-_159459999 0.480 NM_001643
APOA2
apolipoprotein A-II
chr19_-_45948211 0.480 C19orf54
chromosome 19 open reading frame 54
chr7_-_27108826 0.476 NM_006735
HOXA2
homeobox A2
chr16_+_29983216 0.476 ALDOA
aldolase A, fructose-bisphosphate
chr1_+_110683467 0.473 NM_022768
RBM15
RNA binding motif protein 15
chr14_+_19993181 0.470 APEX1
APEX nuclease (multifunctional DNA repair enzyme) 1
chr17_-_44042924 0.469 HOXB7
homeobox B7
chr22_+_36928972 0.466 NM_001161573
MAFF
v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr10_-_18988172 0.464


chr5_-_176663265 0.458 NM_001031677
NM_130781
RAB24

RAB24, member RAS oncogene family

chr6_+_36670067 0.457 NM_003017
SRSF3
serine/arginine-rich splicing factor 3
chr6_+_138230045 0.455 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr2_+_223625105 0.455 NM_080671
KCNE4
potassium voltage-gated channel, Isk-related family, member 4
chr2_+_74914742 0.453 HK2
hexokinase 2
chr20_+_43028590 0.445 STK4
serine/threonine kinase 4
chr17_-_44022595 0.445 HOXB3
homeobox B3
chr19_+_1358750 0.444 DAZAP1
DAZ associated protein 1
chr14_-_63830830 0.443 NM_001040275
NM_001437
ESR2

estrogen receptor 2 (ER beta)

chr6_+_35852369 0.442 NM_207409
C6orf126
chromosome 6 open reading frame 126
chr17_-_46692369 0.440 NM_017643
MBTD1
mbt domain containing 1
chr16_+_29983473 0.440 NM_001127617
ALDOA
aldolase A, fructose-bisphosphate
chr17_+_34610097 0.438 RPL19
ribosomal protein L19
chr9_+_6747636 0.436 NM_001146694
NM_001146695
NM_015061
KDM4C


lysine (K)-specific demethylase 4C


chr12_+_6514645 0.436 GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr17_-_41018291 0.436


chr16_+_4837912 0.435 NM_001079514
UBN1
ubinuclein 1
chr2_+_215885063 0.434 ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr5_+_134012133 0.433 NM_021982
SEC24A
SEC24 family, member A (S. cerevisiae)
chr6_+_36670117 0.431 SRSF3
serine/arginine-rich splicing factor 3
chr14_-_19993032 0.430 NM_017807
OSGEP
O-sialoglycoprotein endopeptidase
chr1_+_10015577 0.429 NM_001105562
NM_006048
UBE4B

ubiquitination factor E4B (UFD2 homolog, yeast)

chr1_+_32992131 0.428


chr8_+_17824631 0.428 NM_006197
PCM1
pericentriolar material 1
chr17_+_6856521 0.426 NM_001004333
RNASEK-C17ORF49
RNASEK
RNASEK-C17orf49 read-through transcript
ribonuclease, RNase K
chr12_+_51686504 0.424 EIF4B
eukaryotic translation initiation factor 4B
chr19_-_45948189 0.423 C19orf54
chromosome 19 open reading frame 54
chr3_-_188946168 0.423 NM_001706
BCL6
B-cell CLL/lymphoma 6

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.30 6.07e-10 GO:0044237 cellular metabolic process
1.25 1.39e-08 GO:0008152 metabolic process
1.14 2.34e-07 GO:0009987 cellular process
1.26 2.52e-07 GO:0044238 primary metabolic process
1.41 3.34e-07 GO:0006807 nitrogen compound metabolic process
1.42 3.66e-07 GO:0034641 cellular nitrogen compound metabolic process
1.43 5.49e-06 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.46 5.86e-06 GO:0044249 cellular biosynthetic process
6.81 6.32e-06 GO:0015682 ferric iron transport
6.81 6.32e-06 GO:0033572 transferrin transport
1.43 3.65e-05 GO:0009058 biosynthetic process
6.32 7.19e-05 GO:0015988 energy coupled proton transport, against electrochemical gradient
6.32 7.19e-05 GO:0015991 ATP hydrolysis coupled proton transport
1.50 9.58e-05 GO:0010467 gene expression
1.50 1.01e-04 GO:0044281 small molecule metabolic process
2.35 1.43e-04 GO:0032870 cellular response to hormone stimulus
2.23 4.71e-04 GO:0071495 cellular response to endogenous stimulus
4.20 6.76e-04 GO:0015992 proton transport
4.07 1.15e-03 GO:0006818 hydrogen transport
1.48 1.15e-03 GO:0034645 cellular macromolecule biosynthetic process
1.26 1.38e-03 GO:0044260 cellular macromolecule metabolic process
1.46 2.34e-03 GO:0009059 macromolecule biosynthetic process
3.18 2.71e-03 GO:0000041 transition metal ion transport
1.39 2.80e-03 GO:0090304 nucleic acid metabolic process
2.38 4.06e-03 GO:0032868 response to insulin stimulus
2.78 6.89e-03 GO:0008286 insulin receptor signaling pathway
2.35 7.19e-03 GO:0071375 cellular response to peptide hormone stimulus
2.06 1.00e-02 GO:0043434 response to peptide hormone stimulus
3.84 1.19e-02 GO:0006826 iron ion transport
3.59 1.48e-02 GO:0006879 cellular iron ion homeostasis
1.69 1.49e-02 GO:0042180 cellular ketone metabolic process
1.21 1.88e-02 GO:0043170 macromolecule metabolic process
1.74 1.99e-02 GO:0009725 response to hormone stimulus
1.68 2.38e-02 GO:0019752 carboxylic acid metabolic process
1.68 2.38e-02 GO:0043436 oxoacid metabolic process
3.43 2.76e-02 GO:0055072 iron ion homeostasis
1.26 3.20e-02 GO:0051179 localization
1.40 3.35e-02 GO:0016070 RNA metabolic process
1.68 3.44e-02 GO:0009719 response to endogenous stimulus
2.40 3.47e-02 GO:0032869 cellular response to insulin stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.24 1.11e-13 GO:0043227 membrane-bounded organelle
1.24 2.23e-13 GO:0043231 intracellular membrane-bounded organelle
1.17 1.31e-12 GO:0044424 intracellular part
1.16 1.82e-12 GO:0005622 intracellular
1.32 4.92e-12 GO:0044444 cytoplasmic part
1.34 7.51e-12 GO:0044446 intracellular organelle part
1.20 7.71e-12 GO:0043226 organelle
1.33 9.80e-12 GO:0044422 organelle part
1.20 1.94e-11 GO:0043229 intracellular organelle
1.53 5.65e-09 GO:0031974 membrane-enclosed lumen
1.20 1.70e-08 GO:0005737 cytoplasm
1.51 5.32e-08 GO:0043233 organelle lumen
1.50 2.05e-07 GO:0070013 intracellular organelle lumen
2.46 6.64e-07 GO:0005773 vacuole
1.65 1.17e-06 GO:0005654 nucleoplasm
1.47 3.89e-06 GO:0044428 nuclear part
8.02 6.19e-06 GO:0033176 proton-transporting V-type ATPase complex
1.50 9.12e-06 GO:0031981 nuclear lumen
2.97 9.71e-06 GO:0044437 vacuolar part
2.92 4.13e-05 GO:0005774 vacuolar membrane
1.22 2.43e-04 GO:0005634 nucleus
4.75 2.46e-04 GO:0016469 proton-transporting two-sector ATPase complex
2.28 2.64e-04 GO:0000323 lytic vacuole
2.28 2.64e-04 GO:0005764 lysosome
1.41 3.08e-04 GO:0005829 cytosol
1.28 8.14e-04 GO:0032991 macromolecular complex
12.16 3.63e-03 GO:0033179 proton-transporting V-type ATPase, V0 domain
1.62 9.25e-03 GO:0031967 organelle envelope
1.61 9.50e-03 GO:0031975 envelope
1.05 1.41e-02 GO:0044464 cell part
2.66 1.42e-02 GO:0005765 lysosomal membrane
1.05 1.44e-02 GO:0005623 cell
1.73 1.50e-02 GO:0030529 ribonucleoprotein complex
1.41 2.70e-02 GO:0005739 mitochondrion

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.23 8.73e-08 GO:0005515 protein binding
1.10 9.24e-04 GO:0005488 binding
1.64 1.83e-03 GO:0003723 RNA binding
6.48 7.13e-03 GO:0046961 proton-transporting ATPase activity, rotational mechanism
4.86 1.20e-02 GO:0019829 cation-transporting ATPase activity
5.05 2.22e-02 GO:0019003 GDP binding