Motif ID: T.p2

Z-value: 1.006


Transcription factors associated with T.p2:

Gene SymbolEntrez IDGene Name
T 6862 T, brachyury homolog (mouse)



Activity profile for motif T.p2.

activity profile for motif T.p2


Sorted Z-values histogram for motif T.p2

Sorted Z-values for motif T.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of T.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_19598912 1.449 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr11_+_61204392 1.426 NM_006133
DAGLA
diacylglycerol lipase, alpha
chrX_-_106033202 1.367 NM_001171706
NM_138382
RIPPLY1

ripply1 homolog (zebrafish)

chr10_+_44726635 1.154 NM_001123376
TMEM72
transmembrane protein 72
chr6_+_37030186 1.075 NM_153370
PI16
peptidase inhibitor 16
chr3_-_127719283 0.914 NM_001165974
NM_144639
UROC1

urocanase domain containing 1

chr11_-_2127368 0.874 NM_001007139
IGF2
insulin-like growth factor 2 (somatomedin A)
chr5_+_31834787 0.821 NM_178140
PDZD2
PDZ domain containing 2
chrX_+_128741562 0.817 NM_018990
SASH3
SAM and SH3 domain containing 3
chr19_+_59657440 0.811


chr12_+_123339662 0.804 NM_181709
FAM101A
family with sequence similarity 101, member A
chr1_-_203557379 0.798 NM_030952
NUAK2
NUAK family, SNF1-like kinase, 2
chr1_+_34997928 0.725 NM_153212
GJB4
gap junction protein, beta 4, 30.3kDa
chr4_-_186693574 0.708 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr19_-_13808101 0.685 LOC284454
hypothetical LOC284454
chr16_+_4325142 0.676 GLIS2
GLIS family zinc finger 2
chr1_-_110949867 0.620 NM_004974
KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr12_-_1791146 0.617 CACNA2D4
calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr6_+_32240357 0.610 NM_030652
EGFL8
EGF-like-domain, multiple 8
chr16_-_66523255 0.606 NM_001907
CTRL
chymotrypsin-like
chrX_+_70360184 0.602 GJB1
gap junction protein, beta 1, 32kDa
chrX_+_128741578 0.597 SASH3
SAM and SH3 domain containing 3
chrX_+_70359780 0.593 NM_000166
GJB1
gap junction protein, beta 1, 32kDa
chr1_+_28458546 0.577 NM_031459
SESN2
sestrin 2
chrX_+_152423277 0.571 BGN
biglycan
chr11_+_73037382 0.567 NM_001130036
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr1_+_32992131 0.554


chr1_+_100777044 0.538 GPR88
G protein-coupled receptor 88
chr1_+_15935395 0.524 NM_207348
SLC25A34
solute carrier family 25, member 34
chrX_+_16714452 0.519 NM_001168683
NM_018360
TXLNG

taxilin gamma

chr12_-_51360439 0.518 NM_006121
KRT1
keratin 1
chr17_-_59304729 0.514 NM_020991
NM_022644
NM_022645
CSH2


chorionic somatomammotropin hormone 2


chr5_+_54355840 0.479 NM_002104
GZMK
granzyme K (granzyme 3; tryptase II)
chr17_-_59327602 0.474 NM_001317
NM_022640
NM_022641
CSH1


CSH2
chorionic somatomammotropin hormone 1 (placental lactogen)


chorionic somatomammotropin hormone 2
chr12_+_55896844 0.463 NM_007224
NXPH4
neurexophilin 4
chr1_+_17719405 0.450 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr11_+_117452936 0.448 NM_001083947
NM_001173551
NM_001173552
NM_019894
TMPRSS4



transmembrane protease, serine 4



chr17_+_41278035 0.446 NM_175882
IMP5
intramembrane protease 5
chr7_+_142723340 0.440 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr11_-_2138984 0.437 NM_000207
NM_001185097
NM_001185098
NM_001042376
INS


INS-IGF2
insulin


INS-IGF2 readthrough transcript
chr11_-_44928803 0.430 NM_001076787
NM_006034
TP53I11

tumor protein p53 inducible protein 11

chr1_+_208008517 0.421 TRAF3IP3
TRAF3 interacting protein 3
chrX_-_53646332 0.418 HUWE1
HECT, UBA and WWE domain containing 1
chr17_+_53761293 0.412 LOC100506779
hypothetical LOC100506779
chrX_+_69559605 0.410 NM_001171191
NM_001171192
NM_001171193
NM_017711
GDPD2



glycerophosphodiester phosphodiesterase domain containing 2



chr10_-_98935369 0.386 SLIT1
slit homolog 1 (Drosophila)
chr19_+_10424581 0.383 NM_006202
PDE4A
phosphodiesterase 4A, cAMP-specific
chrX_-_18600108 0.378 NM_000330
RS1
retinoschisin 1
chr19_-_14121728 0.362 LPHN1
latrophilin 1
chr1_-_21478571 0.356 NM_001113347
ECE1
endothelin converting enzyme 1
chr16_+_25135783 0.353 NM_001169
AQP8
aquaporin 8
chr11_+_61279436 0.350 NM_013279
C11orf9
chromosome 11 open reading frame 9
chr3_-_19950675 0.350 NM_144715
EFHB
EF-hand domain family, member B
chrX_+_106048245 0.329 NM_001171095
CLDN2
claudin 2
chr3_-_48573556 0.314 PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr2_-_100088760 0.312 AFF3
AF4/FMR2 family, member 3
chr5_+_96237923 0.310 ERAP2
endoplasmic reticulum aminopeptidase 2
chr21_+_42364494 0.298 NM_001004416
NM_173568
UMODL1

uromodulin-like 1

chr7_+_99865340 0.286 MEPCE
methylphosphate capping enzyme
chr18_-_27594696 0.286 NM_001034172
MCART2
mitochondrial carrier triple repeat 2
chr3_-_95230143 0.285 NM_001001850
STX19
syntaxin 19
chr1_-_37272295 0.279 NM_000831
GRIK3
glutamate receptor, ionotropic, kainate 3
chr11_-_124311512 0.277 NM_152722
HEPACAM
hepatic and glial cell adhesion molecule
chrX_+_90976314 0.275 NM_014522
NM_032968
NM_032969
PCDH11X


protocadherin 11 X-linked


chr19_+_60279032 0.268 NM_133180
EPS8L1
EPS8-like 1
chr1_+_201286933 0.266 NM_015053
PPFIA4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr1_-_12830728 0.265 NM_001146181
HNRNPCL1
LOC649330
heterogeneous nuclear ribonucleoprotein C-like 1
heterogeneous nuclear ribonucleoprotein C-like
chr11_-_62445587 0.262 NM_000738
CHRM1
cholinergic receptor, muscarinic 1
chr16_-_4263056 0.258 TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr11_-_123816190 0.257 NM_012378
OR8B8
olfactory receptor, family 8, subfamily B, member 8
chr3_+_47004457 0.250 NBEAL2
neurobeachin-like 2
chr15_+_89248423 0.250 NM_006122
MAN2A2
mannosidase, alpha, class 2A, member 2
chr17_+_77219703 0.242 NM_031945
TSPAN10
tetraspanin 10
chr11_+_73036241 0.240 NM_001130034
NM_001130035
PLEKHB1

pleckstrin homology domain containing, family B (evectins) member 1

chr16_+_56211150 0.240 GPR56
G protein-coupled receptor 56
chr17_+_7402315 0.238 NM_001198622
NM_001198623
NM_001198624
NM_003808
NM_172087
NM_172088
TNFSF13





tumor necrosis factor (ligand) superfamily, member 13





chr9_-_116190038 0.237 AKNA
AT-hook transcription factor
chr17_+_45706786 0.231 NM_153229
TMEM92
transmembrane protein 92
chr11_+_68818175 0.231 NM_138768
MYEOV
myeloma overexpressed (in a subset of t(11;14) positive multiple myelomas)
chr1_+_37795101 0.229 NM_003462
DNALI1
dynein, axonemal, light intermediate chain 1
chr5_+_1278469 0.228 NM_182632
SLC6A18
solute carrier family 6, member 18
chr1_+_33003814 0.224 NM_001198972
NM_001198973
KIAA1522

KIAA1522

chr4_-_15686838 0.223 NM_001145849
NM_001145850
NM_001145851
NM_001145852
NM_006017
PROM1




prominin 1




chr15_-_81271859 0.220 NM_001007122
FSD2
fibronectin type III and SPRY domain containing 2
chr11_-_118405288 0.220 NM_001164280
SLC37A4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr1_+_17404206 0.220 NM_013358
PADI1
peptidyl arginine deiminase, type I
chr6_+_107917965 0.219 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr3_+_38282301 0.219 NM_004256
SLC22A13
solute carrier family 22 (organic anion transporter), member 13
chr17_+_18320822 0.219 NM_001040078
LGALS9B
LGALS9C
lectin, galactoside-binding, soluble, 9B
lectin, galactoside-binding, soluble, 9C
chr8_-_42353719 0.207 NM_014420
DKK4
dickkopf homolog 4 (Xenopus laevis)
chr1_+_559618 0.205


chr19_+_2240996 0.203


chr1_-_201321711 0.202 MYOG
myogenin (myogenic factor 4)
chr6_-_33787479 0.202 NM_032340
C6orf125
chromosome 6 open reading frame 125
chr11_-_110755112 0.201 POU2AF1
POU class 2 associating factor 1
chr4_+_8633116 0.201 NM_080819
GPR78
G protein-coupled receptor 78
chr9_-_14712669 0.197 NM_005454
CER1
cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis)
chr19_+_40213431 0.196 NM_001037
NM_199037
SCN1B

sodium channel, voltage-gated, type I, beta

chr5_+_137447479 0.196 NM_058244
WNT8A
wingless-type MMTV integration site family, member 8A
chr1_+_211190631 0.195 VASH2
vasohibin 2
chr6_-_31728121 0.195 NM_001098534
BAG6
BCL2-associated athanogene 6
chr11_+_9736408 0.194 LOC283104
hypothetical LOC283104
chr11_+_46358909 0.194 NM_001012334
MDK
midkine (neurite growth-promoting factor 2)
chr3_-_15115656 0.193 NM_022340
ZFYVE20
zinc finger, FYVE domain containing 20
chr17_-_59342319 0.184 NM_001318
NM_022579
NM_022580
NM_022581
CSHL1



chorionic somatomammotropin hormone-like 1



chr19_+_7734034 0.183 NM_001144904
NM_001144905
NM_001144906
NM_001144907
NM_001144908
NM_001144909
NM_001144910
NM_001144911
NM_014257
CLEC4M








C-type lectin domain family 4, member M








chr1_-_12599934 0.183 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr3_+_46423682 0.180 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr20_+_42777298 0.179 NM_003881
WISP2
WNT1 inducible signaling pathway protein 2
chr1_-_1131795 0.177 NM_004195
NM_148901
NM_148902
TNFRSF18


tumor necrosis factor receptor superfamily, member 18


chr7_-_13992351 0.176 NM_001163150
NM_001163151
NM_001163152
ETV1


ets variant 1


chr19_+_52215982 0.176 NM_002517
NPAS1
neuronal PAS domain protein 1
chr8_-_38577891 0.175


chr1_+_39229474 0.175 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr17_-_37560461 0.174 RAB5C
RAB5C, member RAS oncogene family
chr10_+_70517823 0.172 NM_002727
SRGN
serglycin
chr7_+_72913424 0.172 NM_182504
WBSCR28
Williams-Beuren syndrome chromosome region 28
chr1_-_35143570 0.172 NM_001080418
DLGAP3
discs, large (Drosophila) homolog-associated protein 3
chr21_-_44926485 0.171 NM_181686
KRTAP12-1
keratin associated protein 12-1
chr17_-_37560514 0.170 RAB5C
RAB5C, member RAS oncogene family
chrX_-_47748204 0.167 NM_001007088
NM_006962
NM_001178099
ZNF182


zinc finger protein 182


chr17_+_56109940 0.166 NM_001099432
NM_017679
BCAS3

breast carcinoma amplified sequence 3

chr6_-_33787413 0.164 C6orf125
chromosome 6 open reading frame 125
chrX_+_48221323 0.162 NM_177434
FTSJ1
FtsJ homolog 1 (E. coli)
chr10_+_118295417 0.161 NM_000936
PNLIP
pancreatic lipase
chr9_-_36266930 0.161 NM_001128227
NM_001190388
GNE

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

chrX_-_10605726 0.158 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr9_+_138991775 0.158 NM_000954
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr3_-_52419056 0.156 BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr16_-_4262696 0.155 TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr3_-_15115652 0.155 ZFYVE20
zinc finger, FYVE domain containing 20
chr7_-_50596238 0.154 NM_000790
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr6_-_32121784 0.153 NM_032470
TNXB
tenascin XB
chr5_+_140844810 0.153 NM_018928
NM_032406
PCDHGC4

protocadherin gamma subfamily C, 4

chr1_-_199259133 0.153 KIF21B
kinesin family member 21B
chr5_-_176365971 0.153 NM_016290
UIMC1
ubiquitin interaction motif containing 1
chr2_+_233029076 0.150 NM_001631
ALPI
alkaline phosphatase, intestinal
chr3_-_52418933 0.147 NM_004656
BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr9_+_138991835 0.146 PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr1_+_26986996 0.146 NM_017837
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr17_-_37560541 0.145 NM_004583
NM_201434
RAB5C

RAB5C, member RAS oncogene family

chr10_-_101680645 0.144 DNMBP
dynamin binding protein
chr19_-_19245177 0.144


chr11_+_68614059 0.144


chr3_-_52419086 0.143 BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr3_-_57653634 0.143 NM_152678
FAM116A
family with sequence similarity 116, member A
chr14_+_74815233 0.143 NM_005252
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr19_-_60458915 0.142 PPP6R1
protein phosphatase 6, regulatory subunit 1
chr1_+_110795271 0.141 NM_032414
PROK1
prokineticin 1
chr11_-_128279670 0.140 C11orf45
chromosome 11 open reading frame 45
chr1_+_54780515 0.137 ACOT11
acyl-CoA thioesterase 11
chr19_-_63556632 0.137 NM_130786
A1BG
alpha-1-B glycoprotein
chr1_+_1836125 0.136 NM_138705
CALML6
calmodulin-like 6
chr4_-_185963859 0.136 ACSL1
acyl-CoA synthetase long-chain family member 1
chr1_-_206125877 0.135


chr3_+_52787478 0.134 NM_001166434
ITIH1
inter-alpha (globulin) inhibitor H1
chr19_+_17723285 0.134 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr16_-_4263001 0.133 NM_003223
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr12_-_51383513 0.132 NM_175078
KRT77
keratin 77
chr6_+_31706345 0.130 PRRC2A
proline-rich coiled-coil 2A
chr11_-_65869113 0.129 NM_001024957
NM_015399
BRMS1

breast cancer metastasis suppressor 1

chr7_+_128136347 0.129 FAM71F1
family with sequence similarity 71, member F1
chr1_-_202595666 0.128 NM_014935
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr11_-_110917632 0.126


chr13_+_108079570 0.125 NM_001198950
MYO16
myosin XVI
chr7_-_149101227 0.125 NM_207336
ZNF467
zinc finger protein 467
chr5_+_176717553 0.124


chr1_+_33003847 0.124 KIAA1522
KIAA1522
chr17_+_8154864 0.124 NM_025014
ARHGEF15
Rho guanine nucleotide exchange factor (GEF) 15
chr5_-_172016174 0.124


chr7_+_72720256 0.123 VPS37D
vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr3_+_10832867 0.122 NM_014229
SLC6A11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr12_-_51065629 0.121 NM_033045
KRT84
keratin 84
chr16_-_87244896 0.119 NM_000101
CYBA
cytochrome b-245, alpha polypeptide
chr17_+_22982372 0.119 LGALS9
lectin, galactoside-binding, soluble, 9
chr11_-_64133908 0.118


chr11_-_116691574 0.114 BACE1
beta-site APP-cleaving enzyme 1
chr1_+_12958129 0.114 NM_001100631
PRAMEF22
PRAME family member 22
chr11_+_60727559 0.114 NM_001079807
PGA3
PGA4
pepsinogen 3, group I (pepsinogen A)
pepsinogen 4, group I (pepsinogen A)
chr1_-_13546097 0.113 NM_001024661
NM_001099854
PRAMEF13
PRAMEF14
PRAME family member 13
PRAME family member 14
chr19_-_9982041 0.113 NM_015719
COL5A3
collagen, type V, alpha 3
chr17_+_22982383 0.112 LGALS9
lectin, galactoside-binding, soluble, 9
chr7_-_99365178 0.112 NM_181538
GJC3
gap junction protein, gamma 3, 30.2kDa
chr11_-_73397929 0.111 NM_003356
NM_022803
UCP3

uncoupling protein 3 (mitochondrial, proton carrier)

chr8_+_22075112 0.110 NM_001172357
NM_001172410
NM_003018
SFTPC


surfactant protein C


chr10_-_23043449 0.110 NM_005028
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr12_+_6517600 0.110


chr3_+_52786642 0.108 NM_002215
ITIH1
inter-alpha (globulin) inhibitor H1
chr18_-_72858037 0.108 NM_001025081
NM_001025090
NM_001025092
NM_002385
MBP



myelin basic protein



chr6_+_33495824 0.105 NM_006772
SYNGAP1
synaptic Ras GTPase activating protein 1
chrX_+_102749489 0.103 NM_001006933
NM_032926
TCEAL3

transcription elongation factor A (SII)-like 3

chr4_+_154083584 0.102 NM_033393
FHDC1
FH2 domain containing 1
chr11_-_119514058 0.101 NM_012101
TRIM29
tripartite motif containing 29
chr15_-_88095363 0.101 NM_018670
MESP1
mesoderm posterior 1 homolog (mouse)
chr12_+_130004404 0.099 NM_198827
GPR133
G protein-coupled receptor 133
chr1_+_26609893 0.098 LIN28A
lin-28 homolog A (C. elegans)
chr21_-_33107813 0.097 NM_001162495
NM_001162496
NM_019596
C21orf62


chromosome 21 open reading frame 62


chr7_-_5536783 0.095 ACTB
actin, beta
chr9_-_130124317 0.094 NM_015679
TRUB2
TruB pseudouridine (psi) synthase homolog 2 (E. coli)
chr7_+_102078007 0.092 NM_001166339
NM_001031618
SPDYE2L
SPDYE2
WBSCR19-like protein 3
speedy homolog E2 (Xenopus laevis)

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.70 2.54e-03 GO:0005576 extracellular region

Gene overrepresentation in function category:

enrichment   p-value GO term description
7.14 4.54e-02 GO:0008307 structural constituent of muscle