Motif ID: TBP.p2

Z-value: 1.714


Transcription factors associated with TBP.p2:

Gene SymbolEntrez IDGene Name
TBP 6908 TATA box binding protein



Activity profile for motif TBP.p2.

activity profile for motif TBP.p2


Sorted Z-values histogram for motif TBP.p2

Sorted Z-values for motif TBP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TBP.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_6226838 5.034 NM_001024598
HES3
hairy and enhancer of split 3 (Drosophila)
chrX_+_153339814 4.082 NM_017514
PLXNA3
plexin A3
chr19_+_2220526 3.669 OAZ1
ornithine decarboxylase antizyme 1
chr1_+_151596953 3.651 NM_002965
S100A9
S100 calcium binding protein A9
chr19_+_2220515 3.515 NM_004152
OAZ1
SPPL2B
ornithine decarboxylase antizyme 1
signal peptide peptidase-like 2B
chr19_+_2220529 3.496 OAZ1
ornithine decarboxylase antizyme 1
chr22_+_38246509 3.281 NM_001675
NM_182810
ATF4

activating transcription factor 4 (tax-responsive enhancer element B67)

chr8_-_143692814 3.273 NM_015193
ARC
activity-regulated cytoskeleton-associated protein
chr3_+_195336631 3.106 HES1
hairy and enhancer of split 1, (Drosophila)
chr17_-_45901173 3.038 NM_001267
CHAD
chondroadherin
chr11_-_2138984 3.036 NM_000207
NM_001185097
NM_001185098
NM_001042376
INS


INS-IGF2
insulin


INS-IGF2 readthrough transcript
chr1_+_148090804 3.012 NM_021059
NM_001005464
HIST2H3C
HIST2H3A
histone cluster 2, H3c
histone cluster 2, H3a
chr1_+_148089251 2.992 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr9_+_91409746 2.980 NM_006705
GADD45G
growth arrest and DNA-damage-inducible, gamma
chrX_+_152699616 2.921 NM_001170760
NM_001170761
NM_014370
SRPK3


SRSF protein kinase 3


chr9_+_139255559 2.886 TUBB2C
tubulin, beta 2C
chr3_+_195336625 2.872 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr11_+_43920385 2.859 NM_001145033
C11orf96
chromosome 11 open reading frame 96
chr11_-_2907169 2.849 NM_003311
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr1_+_12839527 2.833 NM_023014
PRAMEF2
PRAME family member 2
chr19_+_12763285 2.822 JUNB
jun B proto-oncogene
chrX_+_153279764 2.765 NM_006013
RPL10
ribosomal protein L10
chr3_+_42702014 2.732 NM_152393
KBTBD5
kelch repeat and BTB (POZ) domain containing 5
chr12_+_50981915 2.724 NM_002284
KRT86
keratin 86
chr1_-_226679648 2.723 NM_003493
HIST3H3
histone cluster 3, H3
chr20_-_38751289 2.651 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr9_+_139255519 2.642 NM_006088
TUBB2C
tubulin, beta 2C
chr11_-_1026654 2.622 NM_005961
MUC6
mucin 6, oligomeric mucus/gel-forming
chr15_+_72828235 2.601 NM_000761
CYP1A2
cytochrome P450, family 1, subfamily A, polypeptide 2
chr11_+_66939720 2.542 NM_001166222
NM_020811
CARNS1

carnosine synthase 1

chr1_+_33319287 2.532 NM_052998
ADC
arginine decarboxylase
chr9_+_139255563 2.529 TUBB2C
tubulin, beta 2C
chr21_+_44844924 2.503 NM_198689
KRTAP10-7
keratin associated protein 10-7
chr19_+_55614006 2.499 NM_003121
SPIB
Spi-B transcription factor (Spi-1/PU.1 related)
chr11_+_60727559 2.481 NM_001079807
PGA3
PGA4
pepsinogen 3, group I (pepsinogen A)
pepsinogen 4, group I (pepsinogen A)
chr19_+_523575 2.452 BSG
basigin (Ok blood group)
chr5_-_179712920 2.440 NM_005110
GFPT2
glutamine-fructose-6-phosphate transaminase 2
chr19_+_523568 2.413 BSG
basigin (Ok blood group)
chr17_+_29707583 2.369 NM_005408
CCL13
chemokine (C-C motif) ligand 13
chr8_+_145393450 2.366 NM_001008271
NM_001080514
SCXA
SCXB
scleraxis homolog A (mouse)
scleraxis homolog B (mouse)
chr19_+_12763295 2.333 NM_002229
JUNB
jun B proto-oncogene
chr16_+_84202515 2.292 NM_001134473
KIAA0182
KIAA0182
chr19_-_40673185 2.285 NM_207392
KRTDAP
keratinocyte differentiation-associated protein
chr9_+_137553104 2.274 NM_002297
LCN1
lipocalin 1 (tear prealbumin)
chr9_+_116125123 2.269 NM_000607
ORM1
orosomucoid 1
chr19_+_2427122 2.236 NM_015675
GADD45B
growth arrest and DNA-damage-inducible, beta
chr8_-_23077392 2.230 NM_003840
TNFRSF10D
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
chr11_+_1607580 2.208 NM_001001480
KRTAP5-5
keratin associated protein 5-5
chr19_+_523403 2.151 NM_001728
NM_198589
BSG

basigin (Ok blood group)

chr11_+_60746396 2.147 NM_001079808
PGA5
PGA3
PGA4
pepsinogen 5, group I (pepsinogen A)
pepsinogen 3, group I (pepsinogen A)
pepsinogen 4, group I (pepsinogen A)
chr11_+_2355099 2.142 CD81
CD81 molecule
chr21_-_42608531 2.098 TFF3
trefoil factor 3 (intestinal)
chr17_-_37034288 2.034 NM_000422
KRT17
keratin 17
chr21_+_43462209 2.017 NM_000394
CRYAA
crystallin, alpha A
chr21_+_33320080 2.008 NM_005806
OLIG2
oligodendrocyte lineage transcription factor 2
chr1_+_150997129 2.006 NM_001025231
KPRP
keratinocyte proline-rich protein
chr11_+_70926718 1.987 NM_021046
KRTAP5-8
keratin associated protein 5-8
chr9_+_116131889 1.980 NM_000608
ORM2
orosomucoid 2
chr17_-_76064842 1.977 NM_002522
NPTX1
neuronal pentraxin I
chr6_+_26264531 1.969 HIST1H1E
histone cluster 1, H1e
chr19_+_6482009 1.965 NM_003811
TNFSF9
tumor necrosis factor (ligand) superfamily, member 9
chr19_-_18763077 1.946 NM_000095
COMP
cartilage oligomeric matrix protein
chr1_+_45822246 1.935 NM_001195193
NM_002482
NM_152298
NASP


nuclear autoantigenic sperm protein (histone-binding)


chr1_-_154941861 1.924 NM_001878
CRABP2
cellular retinoic acid binding protein 2
chr15_+_60146467 1.903 NM_207322
C2CD4A
C2 calcium-dependent domain containing 4A
chr11_+_60765219 1.902 NM_014224
PGA5
pepsinogen 5, group I (pepsinogen A)
chr11_+_65945050 1.888 NM_178864
NPAS4
neuronal PAS domain protein 4
chr19_+_53650577 1.888 NM_013348
KCNJ14
potassium inwardly-rectifying channel, subfamily J, member 14
chr17_-_59327602 1.871 NM_001317
NM_022640
NM_022641
CSH1


CSH2
chorionic somatomammotropin hormone 1 (placental lactogen)


chorionic somatomammotropin hormone 2
chr16_+_1230678 1.868 NM_003294
TPSB2
TPSAB1
tryptase beta 2 (gene/pseudogene)
tryptase alpha/beta 1
chr20_+_31287462 1.854 NM_016583
NM_130852
PLUNC

palate, lung and nasal epithelium associated

chr1_-_226202210 1.844 NM_003395
WNT9A
wingless-type MMTV integration site family, member 9A
chr1_-_151784889 1.840 NM_002961
NM_019554
S100A4

S100 calcium binding protein A4

chr12_-_51585004 1.830 NM_002273
KRT8
keratin 8
chr17_+_7699100 1.792 NM_203411
TMEM88
transmembrane protein 88
chr11_-_1576057 1.785 NM_001004325
KRTAP5-2
keratin associated protein 5-2
chr9_+_135491305 1.779 NM_000787
DBH
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr1_+_12774132 1.761 NM_023013
PRAMEF1
PRAME family member 1
chr17_-_59304729 1.728 NM_020991
NM_022644
NM_022645
CSH2


chorionic somatomammotropin hormone 2


chr1_-_2451543 1.720 NM_001010926
HES5
hairy and enhancer of split 5 (Drosophila)
chr19_+_13124870 1.711 IER2
immediate early response 2
chr22_+_28206180 1.706 NM_021076
NEFH
neurofilament, heavy polypeptide
chr1_-_202432165 1.705 NM_002256
KISS1
KiSS-1 metastasis-suppressor
chr12_+_6514160 1.685 GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr12_+_6514228 1.672 GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr12_-_51047521 1.660 NM_002283
KRT85
keratin 85
chr10_-_46601687 1.657 NM_001137556
NM_001137549
NM_001137548
FAM25B
FAM25G
FAM25C
family with sequence similarity 25, member B
family with sequence similarity 25, member G
family with sequence similarity 25, member C
chr12_+_48630790 1.655 NM_000486
AQP2
aquaporin 2 (collecting duct)
chr11_-_8982107 1.647 NM_020645
NRIP3
nuclear receptor interacting protein 3
chr4_+_37569093 1.647 NM_015173
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr17_+_77910411 1.635 NM_207459
TEX19
testis expressed 19
chr1_+_151147646 1.628 NM_005547
IVL
involucrin
chrX_-_139414890 1.622 NM_005634
SOX3
SRY (sex determining region Y)-box 3
chrX_+_117841761 1.591 NM_173798
ZCCHC12
zinc finger, CCHC domain containing 12
chr21_-_42608774 1.579 NM_003226
TFF3
trefoil factor 3 (intestinal)
chr11_-_62539857 1.571 NM_001184732
NM_001184733
NM_001184736
NM_004254
SLC22A8



solute carrier family 22 (organic anion transporter), member 8



chr17_-_37144408 1.569 NM_001079870
NM_001079871
NM_177977
HAP1


huntingtin-associated protein 1


chr1_-_205012348 1.564 NM_000572
IL10
interleukin 10
chr16_+_57091546 1.562 NDRG4
NDRG family member 4
chr21_-_44795769 1.560 NM_198693
KRTAP10-2
keratin associated protein 10-2
chr6_+_26264537 1.559 NM_005321
HIST1H1E
histone cluster 1, H1e
chr11_+_2355119 1.550 NM_004356
CD81
CD81 molecule
chr12_-_51173238 1.539 NM_005554
KRT6A
keratin 6A
chr12_+_6846955 1.537 TPI1
triosephosphate isomerase 1
chr8_+_133948384 1.533 NM_003235
TG
thyroglobulin
chr16_-_66523255 1.508 NM_001907
CTRL
chymotrypsin-like
chr21_-_42659671 1.504 NM_003225
TFF1
trefoil factor 1
chr16_+_25135783 1.463 NM_001169
AQP8
aquaporin 8
chr9_+_137694988 1.437 NM_001001676
LCN9
lipocalin 9
chr9_+_136912474 1.436 NM_004108
NM_015837
FCN2

ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)

chr6_-_137857213 1.436 NM_175747
OLIG3
oligodendrocyte transcription factor 3
chr1_-_1139358 1.427 NM_003327
TNFRSF4
tumor necrosis factor receptor superfamily, member 4
chr15_-_72804763 1.413 NM_000499
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr7_-_25234582 1.411 NM_022150
NPVF
neuropeptide VF precursor
chr7_-_100595552 1.402 NM_003378
VGF
VGF nerve growth factor inducible
chr5_+_1254709 1.391 NM_001003841
SLC6A19
solute carrier family 6 (neutral amino acid transporter), member 19
chr5_+_132021763 1.389 NM_002188
IL13
interleukin 13
chr11_+_1064869 1.383 NM_002457
MUC2
mucin 2, oligomeric mucus/gel-forming
chr19_+_17979921 1.371 NM_015683
ARRDC2
arrestin domain containing 2
chr16_+_55230078 1.369 NM_005946
MT1A
metallothionein 1A
chr1_-_201411533 1.368 NM_004997
MYBPH
myosin binding protein H
chr9_-_116920232 1.364 NM_002160
TNC
tenascin C
chr6_-_169395847 1.357 THBS2
thrombospondin 2
chr8_-_27528105 1.353 CLU
clusterin
chr16_+_55249355 1.352 NM_005949
MT1F
metallothionein 1F
chr2_-_43306650 1.339 ZFP36L2
zinc finger protein 36, C3H type-like 2
chr5_+_133479196 1.335 NM_001134851
NM_201632
NM_201634
NM_213648
TCF7



transcription factor 7 (T-cell specific, HMG-box)



chr11_-_47330797 1.335 NM_000256
MYBPC3
myosin binding protein C, cardiac
chr17_-_37022465 1.333 NM_005557
KRT16
keratin 16
chr6_-_33879734 1.321 NM_001040109
NM_001184698
NM_002418
MLN


motilin


chr9_+_138677197 1.320 NM_201446
NM_016215
EGFL7

EGF-like-domain, multiple 7

chr3_+_150675169 1.320 TM4SF4
transmembrane 4 L six family member 4
chr14_+_74815233 1.316 NM_005252
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr10_-_71871444 1.311 NM_018055
NODAL
nodal homolog (mouse)
chr6_+_31910623 1.304 NM_001040437
NM_001040438
C6orf48

chromosome 6 open reading frame 48

chr21_+_44818033 1.299 NM_198687
KRTAP10-4
keratin associated protein 10-4
chr16_+_155972 1.284 NM_001003938
HBM
hemoglobin, mu
chr17_+_76623540 1.278 NM_001144888
NM_006340
NM_017450
NM_017451
BAIAP2



BAI1-associated protein 2



chr11_+_1141578 1.277 MUC5AC
mucin 5AC, oligomeric mucus/gel-forming
chr17_-_36209672 1.275 NM_181535
KRT28
keratin 28
chr19_+_46286207 1.272 NM_000766
CYP2A13
cytochrome P450, family 2, subfamily A, polypeptide 13
chr11_+_76561471 1.269 MYO7A
myosin VIIA
chr7_+_30917939 1.257 NM_198098
AQP1
aquaporin 1 (Colton blood group)
chr17_+_76623553 1.250 BAIAP2
BAI1-associated protein 2
chr19_+_52504914 1.247 NM_001736
C5AR1
complement component 5a receptor 1
chr2_-_27384617 1.246 NM_003353
UCN
urocortin
chr10_-_71871364 1.245 NODAL
nodal homolog (mouse)
chr1_-_148079357 1.242 NM_021059
NM_001005464
HIST2H3C
HIST2H3A
histone cluster 2, H3c
histone cluster 2, H3a
chr16_+_55217180 1.235 MT1E
metallothionein 1E
chr21_+_44881700 1.235 NM_181688
KRTAP10-10
keratin associated protein 10-10
chr17_-_59342319 1.224 NM_001318
NM_022579
NM_022580
NM_022581
CSHL1



chorionic somatomammotropin hormone-like 1



chr16_+_55217085 1.221 NM_175617
MT1E
metallothionein 1E
chr19_-_54618410 1.218 NM_178449
PTH2
parathyroid hormone 2
chr10_+_6284845 1.216 NM_004566
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr6_+_36670113 1.203 SRSF3
serine/arginine-rich splicing factor 3
chr19_+_13124889 1.192 IER2
immediate early response 2
chr11_-_2863536 1.190 NM_000076
NM_001122630
NM_001122631
CDKN1C


cyclin-dependent kinase inhibitor 1C (p57, Kip2)


chr9_+_123088217 1.182 GSN
gelsolin
chr17_-_59349867 1.179 NM_000515
NM_022559
NM_022560
NM_022561
NM_022562
GH1




growth hormone 1




chr5_+_170747312 1.170 NM_001037738
NM_002520
NM_199185
NPM1


nucleophosmin (nucleolar phosphoprotein B23, numatrin)


chr12_+_6513865 1.168 NM_002046
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr5_+_176744037 1.163 NM_001167579
NM_003052
SLC34A1

solute carrier family 34 (sodium phosphate), member 1

chr7_+_142723340 1.151 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr10_-_44794146 1.129 NM_007021
C10orf10
chromosome 10 open reading frame 10
chr19_+_13999959 1.129 NM_080864
RLN3
relaxin 3
chr12_+_50913274 1.125 KRT7
keratin 7
chr1_+_150749943 1.120 NM_178438
LCE5A
late cornified envelope 5A
chr16_+_69950116 1.106 NM_001740
NM_007088
CALB2

calbindin 2

chr19_+_810658 1.106 NM_001928
CFD
complement factor D (adipsin)
chr19_-_2002222 1.106 NM_017572
NM_199054
MKNK2

MAP kinase interacting serine/threonine kinase 2

chr1_-_199732323 1.097 NM_001193572
CSRP1
cysteine and glycine-rich protein 1
chr6_-_2848460 1.085 NM_004155
SERPINB9
serpin peptidase inhibitor, clade B (ovalbumin), member 9
chr6_+_33347776 1.085 NM_022551
RPS18
ribosomal protein S18
chr6_+_36670117 1.077 SRSF3
serine/arginine-rich splicing factor 3
chr16_+_142853 1.075 NM_005332
HBZ
hemoglobin, zeta
chr1_-_16355013 1.075 NM_004431
EPHA2
EPH receptor A2
chr12_-_51360439 1.067 NM_006121
KRT1
keratin 1
chr19_+_19183763 1.059 NM_004386
NCAN
neurocan
chr1_-_151630168 1.057 NM_002964
S100A8
S100 calcium binding protein A8
chr11_+_68208583 1.046 GAL
galanin prepropeptide
chr22_+_29810981 1.046 SMTN
smoothelin
chr1_-_148124738 1.043 NM_003528
HIST2H2BE
histone cluster 2, H2be
chr11_-_76059435 1.039 NM_001128922
LRRC32
leucine rich repeat containing 32
chr15_+_78858763 1.027 NM_018689
KIAA1199
KIAA1199
chr17_+_7328412 1.023 NM_000937
POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr17_+_35425139 1.022 NM_000759
NM_001178147
NM_172219
NM_172220
CSF3



colony stimulating factor 3 (granulocyte)



chr12_+_6846844 1.007 NM_001159287
NM_000365
TPI1

triosephosphate isomerase 1

chr7_+_99864348 1.007 NM_001194990
NM_001194991
NM_001194992
MEPCE


methylphosphate capping enzyme


chr16_+_69950138 1.007 CALB2
calbindin 2
chr9_-_138742420 1.005 SNORA43
SNHG7
small nucleolar RNA, H/ACA box 43
small nucleolar RNA host gene 7 (non-protein coding)
chr11_+_1675000 0.997 NM_001012416
KRTAP5-6
keratin associated protein 5-6
chr12_+_47945086 0.980 NM_032704
TUBA1C
tubulin, alpha 1c
chr1_+_148125090 0.971 NM_003517
HIST2H2AC
histone cluster 2, H2ac
chr1_+_37712767 0.965 ZC3H12A
zinc finger CCCH-type containing 12A
chr1_+_17448179 0.963 NM_016233
PADI3
peptidyl arginine deiminase, type III
chr6_-_30692995 0.962 NM_002714
PPP1R10
protein phosphatase 1, regulatory (inhibitor) subunit 10
chr1_+_42391678 0.958 NM_007102
GUCA2B
guanylate cyclase activator 2B (uroguanylin)
chr14_+_93562500 0.949 OTUB2
OTU domain, ubiquitin aldehyde binding 2
chr12_+_129212955 0.946 NM_007197
FZD10
frizzled homolog 10 (Drosophila)
chr10_+_118370441 0.943 NM_005396
PNLIPRP2
pancreatic lipase-related protein 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
7.09 6.93e-12 GO:0034728 nucleosome organization
7.22 5.75e-11 GO:0006334 nucleosome assembly
4.17 1.36e-10 GO:0010035 response to inorganic substance
6.86 1.93e-10 GO:0031497 chromatin assembly
6.20 5.94e-10 GO:0071824 protein-DNA complex subunit organization
6.28 1.42e-09 GO:0065004 protein-DNA complex assembly
1.93 1.53e-09 GO:0048513 organ development
3.10 2.62e-09 GO:0034621 cellular macromolecular complex subunit organization
5.48 1.03e-08 GO:0006323 DNA packaging
1.63 1.74e-08 GO:0048856 anatomical structure development
1.78 2.16e-08 GO:0042221 response to chemical stimulus
5.12 4.67e-08 GO:0006333 chromatin assembly or disassembly
4.90 4.77e-08 GO:0071103 DNA conformation change
2.44 4.79e-08 GO:0006952 defense response
1.54 5.34e-08 GO:0032502 developmental process
1.65 6.96e-08 GO:0048731 system development
1.57 9.16e-08 GO:0007275 multicellular organismal development
2.38 1.29e-07 GO:0043933 macromolecular complex subunit organization
1.41 1.64e-07 GO:0032501 multicellular organismal process
1.70 2.13e-07 GO:0006950 response to stress
2.27 6.06e-07 GO:0051704 multi-organism process
3.08 2.04e-06 GO:0034622 cellular macromolecular complex assembly
2.33 3.53e-06 GO:0006955 immune response
12.17 3.98e-06 GO:0042743 hydrogen peroxide metabolic process
2.22 5.76e-06 GO:0009888 tissue development
8.76 7.89e-06 GO:0072593 reactive oxygen species metabolic process
8.35 1.47e-05 GO:0034614 cellular response to reactive oxygen species
2.43 2.31e-05 GO:0009725 response to hormone stimulus
10.43 2.36e-05 GO:0070301 cellular response to hydrogen peroxide
1.92 2.78e-05 GO:0002376 immune system process
2.29 3.67e-05 GO:0065003 macromolecular complex assembly
1.90 4.64e-05 GO:0010033 response to organic substance
3.17 4.70e-05 GO:0006954 inflammatory response
2.08 5.00e-05 GO:0070887 cellular response to chemical stimulus
12.98 9.32e-05 GO:0042744 hydrogen peroxide catabolic process
6.33 1.33e-04 GO:0034599 cellular response to oxidative stress
2.26 1.44e-04 GO:0009719 response to endogenous stimulus
1.84 1.84e-04 GO:0051239 regulation of multicellular organismal process
3.54 1.87e-04 GO:0008544 epidermis development
3.18 2.43e-04 GO:0009617 response to bacterium
3.74 2.57e-04 GO:0010038 response to metal ion
5.84 3.62e-04 GO:0042542 response to hydrogen peroxide
4.92 4.48e-04 GO:0000302 response to reactive oxygen species
2.39 6.68e-04 GO:0009607 response to biotic stimulus
4.66 9.37e-04 GO:0007586 digestion
1.97 1.07e-03 GO:0009611 response to wounding
2.54 1.09e-03 GO:0051707 response to other organism
1.87 1.54e-03 GO:0022607 cellular component assembly
6.95 1.74e-03 GO:0031424 keratinization
2.21 1.85e-03 GO:0009887 organ morphogenesis
5.95 2.63e-03 GO:0051591 response to cAMP
1.54 3.51e-03 GO:0065008 regulation of biological quality
1.78 3.71e-03 GO:0044085 cellular component biogenesis
2.02 3.92e-03 GO:0071844 cellular component assembly at cellular level
3.23 5.42e-03 GO:0006979 response to oxidative stress
1.90 5.98e-03 GO:0042592 homeostatic process
4.02 6.46e-03 GO:0007565 female pregnancy
2.74 1.05e-02 GO:0048545 response to steroid hormone stimulus
1.85 1.39e-02 GO:0050793 regulation of developmental process
3.97 1.58e-02 GO:0008217 regulation of blood pressure
1.99 1.61e-02 GO:0002682 regulation of immune system process
14.60 1.74e-02 GO:0046689 response to mercury ion
2.04 2.33e-02 GO:0048878 chemical homeostasis
7.86 3.29e-02 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
2.62 3.51e-02 GO:0001817 regulation of cytokine production
1.48 4.48e-02 GO:0030154 cell differentiation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.38 3.14e-25 GO:0005576 extracellular region
3.49 2.35e-24 GO:0005615 extracellular space
3.08 7.88e-24 GO:0044421 extracellular region part
7.35 6.35e-23 GO:0005882 intermediate filament
10.59 1.97e-20 GO:0045095 keratin filament
6.36 2.83e-20 GO:0045111 intermediate filament cytoskeleton
10.83 3.10e-16 GO:0000786 nucleosome
6.93 1.96e-11 GO:0032993 protein-DNA complex
3.39 4.71e-06 GO:0000785 chromatin
1.89 5.53e-05 GO:0044430 cytoskeletal part
1.48 1.23e-04 GO:0043228 non-membrane-bounded organelle
1.48 1.23e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.63 6.54e-04 GO:0005856 cytoskeleton
1.34 2.82e-03 GO:0032991 macromolecular complex
2.89 3.67e-03 GO:0030141 stored secretory granule
9.74 4.46e-03 GO:0032982 myosin filament

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.17 3.65e-14 GO:0005198 structural molecule activity
7.38 5.04e-13 GO:0005179 hormone activity
2.37 7.43e-11 GO:0005102 receptor binding
4.11 4.54e-08 GO:0005125 cytokine activity
3.95 1.07e-06 GO:0005126 cytokine receptor binding
29.20 1.58e-05 GO:0046870 cadmium ion binding
6.18 3.51e-04 GO:0005507 copper ion binding
1.18 6.53e-03 GO:0005515 protein binding
5.72 6.84e-03 GO:0008009 chemokine activity
3.12 9.19e-03 GO:0008083 growth factor activity
29.20 1.44e-02 GO:0005549 odorant binding
5.16 1.63e-02 GO:0016209 antioxidant activity
5.16 1.63e-02 GO:0042379 chemokine receptor binding
10.43 2.47e-02 GO:0050664 oxidoreductase activity, acting on NADH or NADPH, oxygen as acceptor
2.89 2.51e-02 GO:0001664 G-protein-coupled receptor binding
14.60 3.01e-02 GO:0015250 water channel activity
6.01 4.24e-02 GO:0004601 peroxidase activity
6.01 4.24e-02 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor