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• Activity deltas table
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Motif ID: TFAP2B.p2

Z-value: 1.690

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_+_41622267	2.793		FOXP4	forkhead box P4
chr2_-_160972606	2.711		RBMS1	RNA binding motif, single stranded interacting protein 1
chr6_+_167970334	2.398	NM_001040000	MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
chr20_+_56899904	2.365		GNAS	GNAS complex locus
chr20_+_56899867	2.347		GNAS	GNAS complex locus
chr6_+_157140954	2.324		ARID1B	AT rich interactive domain 1B (SWI1-like)
chr17_+_75849221	2.204	NM_020914 NM_020954	RNF213	ring finger protein 213
chr10_+_104394185	2.185	NM_030912	TRIM8	tripartite motif containing 8
chr20_+_56899643	2.155	NM_001077489 NM_000516 NM_080426	GNAS	GNAS complex locus
chr6_+_41622111	2.136	NM_001012426 NM_001012427 NM_138457	FOXP4	forkhead box P4
chr16_+_49139694	2.001	NM_033119	NKD1	naked cuticle homolog 1 (Drosophila)
chr2_+_96845704	1.972	NM_017623 NM_199078	CNNM3	cyclin M3
chr6_+_157140733	1.848	NM_017519 NM_020732	ARID1B	AT rich interactive domain 1B (SWI1-like)
chr9_+_95378492	1.823	NM_005392	PHF2	PHD finger protein 2
chr22_+_48740432	1.801		PIM3	pim-3 oncogene
chr2_+_236067687	1.708		AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr16_+_87047418	1.688	NM_153813	ZFPM1	zinc finger protein, multitype 1
chr13_+_112392355	1.677	NM_015205 NM_032189	ATP11A	ATPase, class VI, type 11A
chr6_+_157140895	1.662
chr8_+_81560971	1.633	NM_001105539 NM_023929	ZBTB10	zinc finger and BTB domain containing 10
chr22_+_48633532	1.577		ZBED4	zinc finger, BED-type containing 4
chr17_+_75366524	1.518	NM_005189 NM_032647	CBX2	chromobox homolog 2
chr2_+_101680594	1.506	NM_004834 NM_145686 NM_145687	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chr16_+_87047159	1.494		ZFPM1	zinc finger protein, multitype 1
chr22_+_20101661	1.477	NM_015094	HIC2	hypermethylated in cancer 2
chr22_+_48633484	1.464	NM_014838	ZBED4	zinc finger, BED-type containing 4
chr20_+_60130866	1.462	NM_144703	LSM14B	LSM14B, SCD6 homolog B (S. cerevisiae)
chr17_+_77582774	1.440	NM_005052	RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr8_+_17398940	1.336	NM_001008539	SLC7A2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chrX_+_152606945	1.324	NM_001142805 NM_005629	SLC6A8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr2_+_236067424	1.322	NM_001037131 NM_014914	AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr2_+_241156776	1.319	NM_018226	RNPEPL1	arginyl aminopeptidase (aminopeptidase B)-like 1
chr20_+_60130963	1.316		LSM14B	LSM14B, SCD6 homolog B (S. cerevisiae)
chr20_-_30636535	1.291		LOC284804	hypothetical protein LOC284804
chr17_+_17525571	1.251
chr13_-_112392051	1.249		LOC440149	hypothetical LOC440149
chr19_+_540849	1.223	NM_001194	HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr18_+_58341637	1.216	NM_017742	ZCCHC2	zinc finger, CCHC domain containing 2
chr9_+_137511448	1.216	NM_014811	KIAA0649	KIAA0649
chr20_+_226200	1.202	NM_033089	ZCCHC3	zinc finger, CCHC domain containing 3
chr20_-_47327998	1.201	NM_021035	ZNFX1	zinc finger, NFX1-type containing 1
chr20_+_56900116	1.198	NM_001077488	GNAS	GNAS complex locus
chr20_-_60151753	1.183		PSMA7	proteasome (prosome, macropain) subunit, alpha type, 7
chr17_+_78630793	1.166	NM_001004431	METRNL	meteorin, glial cell differentiation regulator-like
chr6_+_36754433	1.154	NM_000389	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr22_+_48740143	1.153	NM_001001852	PIM3	pim-3 oncogene
chr16_+_88517187	1.152	NM_006086	TUBB3	tubulin, beta 3
chr20_-_60151802	1.139		PSMA7	proteasome (prosome, macropain) subunit, alpha type, 7
chr20_+_48241334	1.129		CEBPB	CCAAT/enhancer binding protein (C/EBP), beta
chr20_-_60151835	1.104	NM_002792	PSMA7	proteasome (prosome, macropain) subunit, alpha type, 7
chr1_-_8406288	1.101	NM_001042682	RERE	arginine-glutamic acid dipeptide (RE) repeats
chr17_+_78070853	1.087	NM_004514	FOXK2	forkhead box K2
chr11_+_67836575	1.070	NM_002335	LRP5	low density lipoprotein receptor-related protein 5
chr21_+_45649429	1.049	NM_130445	COL18A1	collagen, type XVIII, alpha 1
chr7_+_137795719	1.032		TRIM24	tripartite motif containing 24
chr20_-_61933012	1.022		ZBTB46	zinc finger and BTB domain containing 46
chr2_+_231610438	1.020	NM_001144994	C2orf72	chromosome 2 open reading frame 72
chr14_+_104852225	1.017		PACS2	phosphofurin acidic cluster sorting protein 2
chr21_+_45649719	1.016
chr9_+_137119339	1.003		OLFM1	olfactomedin 1
chr9_+_137119334	0.992		OLFM1	olfactomedin 1
chr6_+_43846155	0.986		VEGFA	vascular endothelial growth factor A
chr20_+_48240867	0.983		CEBPB	CCAAT/enhancer binding protein (C/EBP), beta
chr5_+_179180517	0.970		SQSTM1	sequestosome 1
chr20_+_4077409	0.960	NM_175839 NM_175840 NM_175841 NM_175842	SMOX	spermine oxidase
chr7_+_150442652	0.953		AGAP3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr17_+_17525497	0.950	NM_030665	RAI1	retinoic acid induced 1
chr6_+_160689355	0.942	NM_021977	SLC22A3	solute carrier family 22 (extraneuronal monoamine transporter), member 3
chr5_+_179180695	0.939		SQSTM1	sequestosome 1
chr22_+_21852911	0.939		BCR	breakpoint cluster region
chr14_+_105063975	0.935	NM_025268	TMEM121	transmembrane protein 121
chr5_+_139008667	0.929		CXXC5	CXXC finger protein 5
chr6_+_37245860	0.925	NM_002648	PIM1	pim-1 oncogene
chr3_+_32834513	0.924	NM_001039111	TRIM71	tripartite motif containing 71
chr18_+_8599407	0.916	NM_001025300	RAB12	RAB12, member RAS oncogene family
chr20_+_4077466	0.916		SMOX	spermine oxidase
chr17_+_63252704	0.911		BPTF	bromodomain PHD finger transcription factor
chr17_+_72880967	0.908		SEPT9	septin 9
chr16_+_2138688	0.900		RAB26	RAB26, member RAS oncogene family
chr20_+_35407872	0.900	NM_198291	SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr20_+_48240772	0.889	NM_005194	CEBPB	CCAAT/enhancer binding protein (C/EBP), beta
chr1_+_9571518	0.884	NM_001010866 NM_001130924	TMEM201	transmembrane protein 201
chr7_+_882766	0.881		GET4	golgi to ER traffic protein 4 homolog (S. cerevisiae)
chr17_+_72376022	0.875	NM_144677	MGAT5B	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
chr6_+_157141565	0.874		ARID1B	AT rich interactive domain 1B (SWI1-like)
chr10_+_82204051	0.873		TSPAN14	tetraspanin 14
chr14_-_22596522	0.871	NM_022478 NM_144985	CDH24	cadherin 24, type 2
chr10_+_82203872	0.867	NM_001128309 NM_030927	TSPAN14	tetraspanin 14
chr14_+_55116549	0.861	NM_001079521 NM_001079522 NM_004986 NM_182926	KTN1	kinectin 1 (kinesin receptor)
chr7_+_882704	0.859	NM_015949	GET4	golgi to ER traffic protein 4 homolog (S. cerevisiae)
chr10_+_82204054	0.854		TSPAN14	tetraspanin 14
chr6_+_36754467	0.851		CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr14_+_99774854	0.850	NM_003403	YY1	YY1 transcription factor
chr19_+_7566698	0.848	NM_001080429 NM_020902	KIAA1543	KIAA1543
chr2_+_8739563	0.847	NM_002166	ID2	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr16_-_87535106	0.841	NM_175931	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr16_-_88410523	0.841	NM_000135 NM_001018112	FANCA	Fanconi anemia, complementation group A
chr9_+_136358145	0.839		RXRA	retinoid X receptor, alpha
chr11_+_566482	0.835	NM_020901	PHRF1	PHD and ring finger domains 1
chr3_+_23961739	0.833	NM_005126	NR1D2	nuclear receptor subfamily 1, group D, member 2
chr16_-_11798507	0.827		ZC3H7A	zinc finger CCCH-type containing 7A
chr6_+_43151922	0.825	NM_002821 NM_152880 NM_152881 NM_152882	PTK7	PTK7 protein tyrosine kinase 7
chr1_+_24944554	0.822		CLIC4	chloride intracellular channel 4
chr6_+_158164294	0.822		SNX9	sorting nexin 9
chr9_+_114288899	0.821	NM_133465	KIAA1958	KIAA1958
chr16_+_66120205	0.816	NM_024519 NM_001193522	FAM65A	family with sequence similarity 65, member A
chr9_+_136358134	0.814	NM_002957	RXRA	retinoid X receptor, alpha
chr4_+_1842833	0.812	NM_001042424	WHSC1	Wolf-Hirschhorn syndrome candidate 1
chr20_-_61028319	0.807	NM_001193369 NM_001193370 NM_080796	DIDO1	death inducer-obliterator 1
chr17_+_59053518	0.805	NM_002401 NM_203351	MAP3K3	mitogen-activated protein kinase kinase kinase 3
chr2_+_242289983	0.805	NM_032329	ING5	inhibitor of growth family, member 5
chr9_+_114289178	0.804		KIAA1958	KIAA1958
chr20_+_2621193	0.802	NM_001110514	EBF4	early B-cell factor 4
chr3_+_43303005	0.799	NM_001100594 NM_017719	SNRK	SNF related kinase
chr12_+_121885930	0.798	NM_003959	HIP1R	huntingtin interacting protein 1 related
chr22_+_36531178	0.797		H1F0	H1 histone family, member 0
chr2_+_239000306	0.794	NM_001040445	ASB1	ankyrin repeat and SOCS box containing 1
chr10_+_99176028	0.789		PGAM1	phosphoglycerate mutase 1 (brain)
chr20_+_56701224	0.786	NM_024663	NPEPL1	aminopeptidase-like 1
chr4_+_1842947	0.785		WHSC1	Wolf-Hirschhorn syndrome candidate 1
chr16_+_3010311	0.783	NM_016639	TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A
chr8_+_61753912	0.782		CHD7	chromodomain helicase DNA binding protein 7
chr22_+_36531059	0.775	NM_005318	H1F0	H1 histone family, member 0
chr3_+_192529567	0.772	NM_174908 NM_178335	CCDC50	coiled-coil domain containing 50
chr5_+_179180509	0.767		SQSTM1	sequestosome 1
chr7_+_6111115	0.767		USP42	ubiquitin specific peptidase 42
chr10_+_82204046	0.765		TSPAN14	tetraspanin 14
chr17_+_59053515	0.764		MAP3K3	mitogen-activated protein kinase kinase kinase 3
chr20_-_46877811	0.758	NM_020820	PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr5_+_179180447	0.757	NM_003900	SQSTM1	sequestosome 1
chr6_+_1556543	0.756		FOXC1	forkhead box C1
chr2_+_9264360	0.756		ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr2_+_239000395	0.754		ASB1	ankyrin repeat and SOCS box containing 1
chr2_+_233927892	0.753		DGKD	diacylglycerol kinase, delta 130kDa
chr7_+_7188667	0.752	NM_020156	C1GALT1	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr19_+_1200882	0.746		MIDN	midnolin
chr16_+_83291107	0.746		USP10	ubiquitin specific peptidase 10
chr20_+_34635362	0.743	NM_021809	TGIF2	TGFB-induced factor homeobox 2
chr19_+_3045528	0.741		GNA11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr9_+_128416542	0.740	NM_001174146 NM_001174147 NM_002316	LMX1B	LIM homeobox transcription factor 1, beta
chr2_+_173129119	0.740		PDK1	pyruvate dehydrogenase kinase, isozyme 1
chr20_+_60151868	0.738	NM_198935	SS18L1	synovial sarcoma translocation gene on chromosome 18-like 1
chr20_-_61600834	0.733	NM_001958	EEF1A2	eukaryotic translation elongation factor 1 alpha 2
chr6_+_2711227	0.731		WRNIP1	Werner helicase interacting protein 1
chr19_+_482688	0.725	NM_004359	CDC34	cell division cycle 34 homolog (S. cerevisiae)
chr17_+_69939806	0.722		GPRC5C	G protein-coupled receptor, family C, group 5, member C
chr1_+_945331	0.722	NM_198576	AGRN	agrin
chr16_+_83291055	0.721	NM_005153	USP10	ubiquitin specific peptidase 10
chr10_-_99175685	0.720
chr17_+_14145051	0.718	NM_006041	HS3ST3B1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr10_+_99176032	0.717		PGAM1	phosphoglycerate mutase 1 (brain)
chr3_+_38470782	0.717	NM_001106	ACVR2B	activin A receptor, type IIB
chr16_+_83291097	0.717		USP10	ubiquitin specific peptidase 10
chr10_+_99176030	0.714		PGAM1	phosphoglycerate mutase 1 (brain)
chr10_+_99176002	0.712		PGAM1	phosphoglycerate mutase 1 (brain)
chr13_+_97593411	0.711	NM_001001715 NM_005766	FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr16_+_1299361	0.708	NM_194260	UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)
chr18_+_18969724	0.708	NM_001100619	CABLES1	Cdk5 and Abl enzyme substrate 1
chr1_+_51474583	0.706		RNF11	ring finger protein 11
chr1_+_2149993	0.706	NM_003036	SKI	v-ski sarcoma viral oncogene homolog (avian)
chr10_+_80498782	0.704	NM_020338	ZMIZ1	zinc finger, MIZ-type containing 1
chr13_+_97593469	0.703		FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr10_+_99175949	0.701		PGAM1	phosphoglycerate mutase 1 (brain)
chr20_-_61108831	0.701	NM_080606	BHLHE23	basic helix-loop-helix family, member e23
chr14_+_35072998	0.699	NM_032594	INSM2	insulinoma-associated 2
chr15_+_97009194	0.699		IGF1R	insulin-like growth factor 1 receptor
chr10_+_80672842	0.698		ZMIZ1	zinc finger, MIZ-type containing 1
chr6_+_158164269	0.696	NM_016224	SNX9	sorting nexin 9
chr2_+_233927880	0.693	NM_152879	DGKD	diacylglycerol kinase, delta 130kDa
chr7_+_2638108	0.690	NM_025250	TTYH3	tweety homolog 3 (Drosophila)
chr1_-_33669190	0.690		PHC2	polyhomeotic homolog 2 (Drosophila)
chr6_+_160068135	0.689	NM_004906 NM_152858	WTAP	Wilms tumor 1 associated protein
chr6_+_43846372	0.687		VEGFA	vascular endothelial growth factor A
chr20_+_5934964	0.686		CRLS1	cardiolipin synthase 1
chr5_+_139008091	0.686		CXXC5	CXXC finger protein 5
chr2_+_236068029	0.685		AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr20_+_5934560	0.683	NM_019095	CRLS1	cardiolipin synthase 1
chr2_+_100802923	0.683	NM_002518	NPAS2	neuronal PAS domain protein 2
chr5_+_139008139	0.682		CXXC5	CXXC finger protein 5
chr16_+_1143738	0.681		CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit
chr10_+_99175967	0.680		PGAM1	phosphoglycerate mutase 1 (brain)
chr16_+_29725665	0.679
chr10_+_99176007	0.678	NM_002629	PGAM1	phosphoglycerate mutase 1 (brain)
chr6_+_64403631	0.677		PHF3	PHD finger protein 3
chr17_+_52517529	0.676	NM_003488	AKAP1	A kinase (PRKA) anchor protein 1
chr2_+_170298487	0.675
chr20_+_24398269	0.674		TMEM90B	transmembrane protein 90B
chr7_+_150414704	0.671	NM_001042535 NM_031946	AGAP3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr20_+_254205	0.670	NM_006943	SOX12	SRY (sex determining region Y)-box 12
chr20_+_5934761	0.669		CRLS1	cardiolipin synthase 1
chr16_+_73590470	0.668		ZNRF1	zinc and ring finger 1
chr5_+_56147109	0.668		MAP3K1	mitogen-activated protein kinase kinase kinase 1
chr17_+_52518098	0.666		AKAP1	A kinase (PRKA) anchor protein 1
chr12_+_67919583	0.665	NM_007007	CPSF6	cleavage and polyadenylation specific factor 6, 68kDa
chr2_+_173129040	0.664		PDK1	pyruvate dehydrogenase kinase, isozyme 1
chr1_+_945399	0.663
chr16_+_73590419	0.661		ZNRF1	zinc and ring finger 1
chr5_+_139008209	0.659	NM_016463	CXXC5	CXXC finger protein 5
chr19_+_1358531	0.657	NM_018959 NM_170711	DAZAP1	DAZ associated protein 1
chr10_+_99175933	0.656		PGAM1	phosphoglycerate mutase 1 (brain)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.10	8.71e-25	GO:0009987	cellular process
1.30	1.42e-16	GO:0048523	negative regulation of cellular process
1.15	4.91e-16	GO:0044237	cellular metabolic process
1.28	8.72e-16	GO:0048519	negative regulation of biological process
1.13	1.01e-14	GO:0050794	regulation of cellular process
1.18	1.58e-14	GO:0044260	cellular macromolecule metabolic process
1.21	2.20e-14	GO:0016043	cellular component organization
1.21	2.53e-14	GO:0071840	cellular component organization or biogenesis
1.24	1.65e-13	GO:0071841	cellular component organization or biogenesis at cellular level
1.24	2.11e-13	GO:0071842	cellular component organization at cellular level
1.12	1.32e-12	GO:0050789	regulation of biological process
1.19	1.39e-12	GO:0031323	regulation of cellular metabolic process
1.32	2.38e-12	GO:0007399	nervous system development
1.19	1.42e-11	GO:0080090	regulation of primary metabolic process
1.11	1.47e-11	GO:0065007	biological regulation
1.19	1.79e-11	GO:0060255	regulation of macromolecule metabolic process
1.11	3.54e-11	GO:0008152	metabolic process
1.38	5.20e-11	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.17	6.81e-11	GO:0019222	regulation of metabolic process
1.31	1.25e-10	GO:0009966	regulation of signal transduction
1.22	4.13e-10	GO:0010468	regulation of gene expression
1.17	4.20e-10	GO:0032502	developmental process
1.14	5.21e-10	GO:0043170	macromolecule metabolic process
1.44	7.27e-10	GO:0009890	negative regulation of biosynthetic process
1.22	9.21e-10	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.50	1.05e-09	GO:0045892	negative regulation of transcription, DNA-dependent
1.27	1.27e-09	GO:0023051	regulation of signaling
1.12	1.34e-09	GO:0044238	primary metabolic process
1.20	2.24e-09	GO:0031326	regulation of cellular biosynthetic process
1.43	2.52e-09	GO:0031327	negative regulation of cellular biosynthetic process
1.21	2.88e-09	GO:0048522	positive regulation of cellular process
1.44	3.27e-09	GO:0010558	negative regulation of macromolecule biosynthetic process
1.45	3.28e-09	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.48	3.86e-09	GO:0051253	negative regulation of RNA metabolic process
1.37	5.18e-09	GO:0031324	negative regulation of cellular metabolic process
1.17	6.33e-09	GO:0007275	multicellular organismal development
1.45	6.42e-09	GO:0010629	negative regulation of gene expression
1.56	7.68e-09	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.22	7.72e-09	GO:0051252	regulation of RNA metabolic process
1.20	9.30e-09	GO:0009889	regulation of biosynthetic process
1.21	1.07e-08	GO:0010556	regulation of macromolecule biosynthetic process
1.34	1.13e-08	GO:0009892	negative regulation of metabolic process
1.27	3.25e-08	GO:0009653	anatomical structure morphogenesis
1.35	4.28e-08	GO:0022008	neurogenesis
1.36	5.82e-08	GO:0048699	generation of neurons
1.19	7.10e-08	GO:0048518	positive regulation of biological process
1.25	8.15e-08	GO:0006996	organelle organization
1.42	1.15e-07	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22	1.15e-07	GO:0048869	cellular developmental process
1.17	1.50e-07	GO:0006807	nitrogen compound metabolic process
1.34	1.59e-07	GO:0010605	negative regulation of macromolecule metabolic process
1.42	1.70e-07	GO:0051172	negative regulation of nitrogen compound metabolic process
1.42	1.85e-07	GO:0000902	cell morphogenesis
1.18	2.01e-07	GO:0051171	regulation of nitrogen compound metabolic process
1.19	2.02e-07	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.30	2.06e-07	GO:0010604	positive regulation of macromolecule metabolic process
1.21	2.89e-07	GO:0006355	regulation of transcription, DNA-dependent
1.16	6.99e-07	GO:0034641	cellular nitrogen compound metabolic process
1.18	7.27e-07	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.21	8.55e-07	GO:0030154	cell differentiation
1.16	1.20e-06	GO:0048856	anatomical structure development
1.47	1.25e-06	GO:0010648	negative regulation of cell communication
1.48	1.52e-06	GO:0009968	negative regulation of signal transduction
1.27	1.53e-06	GO:0009893	positive regulation of metabolic process
1.30	1.58e-06	GO:0010646	regulation of cell communication
1.51	1.58e-06	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.46	1.86e-06	GO:0023057	negative regulation of signaling
1.20	1.93e-06	GO:0090304	nucleic acid metabolic process
1.37	3.31e-06	GO:0051254	positive regulation of RNA metabolic process
1.37	3.76e-06	GO:0010628	positive regulation of gene expression
1.38	3.85e-06	GO:0032989	cellular component morphogenesis
1.42	5.89e-06	GO:0000904	cell morphogenesis involved in differentiation
1.22	6.14e-06	GO:0016070	RNA metabolic process
1.35	7.45e-06	GO:0009790	embryo development
1.21	1.02e-05	GO:0006464	protein modification process
1.41	1.09e-05	GO:0032990	cell part morphogenesis
1.17	1.42e-05	GO:0044267	cellular protein metabolic process
1.16	1.43e-05	GO:0048731	system development
1.41	1.44e-05	GO:0048858	cell projection morphogenesis
1.26	2.05e-05	GO:0031325	positive regulation of cellular metabolic process
1.36	2.32e-05	GO:0045893	positive regulation of transcription, DNA-dependent
1.44	2.40e-05	GO:0032583	regulation of gene-specific transcription
1.20	2.42e-05	GO:0010467	gene expression
1.20	3.42e-05	GO:0043412	macromolecule modification
1.40	4.53e-05	GO:0048585	negative regulation of response to stimulus
1.45	9.91e-05	GO:0016568	chromatin modification
1.29	1.02e-04	GO:0006351	transcription, DNA-dependent
1.33	1.04e-04	GO:0030182	neuron differentiation
1.42	1.18e-04	GO:0007409	axonogenesis
1.34	1.39e-04	GO:0030030	cell projection organization
1.75	1.60e-04	GO:0030111	regulation of Wnt receptor signaling pathway
1.13	1.74e-04	GO:0051179	localization
1.23	2.02e-04	GO:0051641	cellular localization
1.40	2.09e-04	GO:0048812	neuron projection morphogenesis
1.47	2.15e-04	GO:0007411	axon guidance
1.30	2.40e-04	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.16	2.47e-04	GO:0009058	biosynthetic process
1.40	2.55e-04	GO:0048667	cell morphogenesis involved in neuron differentiation
1.26	2.56e-04	GO:0032268	regulation of cellular protein metabolic process
1.19	2.87e-04	GO:0048583	regulation of response to stimulus
1.32	4.21e-04	GO:0007167	enzyme linked receptor protein signaling pathway
1.16	4.25e-04	GO:0044249	cellular biosynthetic process
1.20	4.43e-04	GO:0034645	cellular macromolecule biosynthetic process
1.25	4.70e-04	GO:0051246	regulation of protein metabolic process
1.42	5.95e-04	GO:0009792	embryo development ending in birth or egg hatching
1.31	6.29e-04	GO:0045595	regulation of cell differentiation
1.22	7.27e-04	GO:0033036	macromolecule localization
1.28	7.33e-04	GO:0051128	regulation of cellular component organization
1.32	7.38e-04	GO:0051276	chromosome organization
1.29	7.64e-04	GO:0010557	positive regulation of macromolecule biosynthetic process
1.42	7.87e-04	GO:0043009	chordate embryonic development
1.26	9.08e-04	GO:0048468	cell development
1.36	9.44e-04	GO:0031175	neuron projection development
1.43	1.02e-03	GO:0007389	pattern specification process
1.33	1.10e-03	GO:0048666	neuron development
1.28	1.13e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
1.19	1.16e-03	GO:0009059	macromolecule biosynthetic process
1.27	1.29e-03	GO:0031328	positive regulation of cellular biosynthetic process
1.50	1.45e-03	GO:0090046	regulation of transcription regulator activity
1.36	1.61e-03	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.50	1.94e-03	GO:0051090	regulation of sequence-specific DNA binding transcription factor activity
1.23	2.12e-03	GO:0008104	protein localization
1.25	2.22e-03	GO:0032774	RNA biosynthetic process
1.43	2.63e-03	GO:0060284	regulation of cell development
1.34	2.65e-03	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.43	2.74e-03	GO:0051098	regulation of binding
1.25	3.02e-03	GO:0050793	regulation of developmental process
1.26	3.64e-03	GO:0009891	positive regulation of biosynthetic process
1.20	4.25e-03	GO:0035556	intracellular signal transduction
1.23	4.59e-03	GO:0006793	phosphorus metabolic process
1.23	4.59e-03	GO:0006796	phosphate metabolic process
1.25	5.29e-03	GO:0008219	cell death
1.34	5.35e-03	GO:0006325	chromatin organization
1.59	6.34e-03	GO:0010553	negative regulation of gene-specific transcription from RNA polymerase II promoter
1.45	6.41e-03	GO:0051101	regulation of DNA binding
1.12	7.19e-03	GO:0007165	signal transduction
1.27	7.81e-03	GO:0012501	programmed cell death
1.25	8.50e-03	GO:0033554	cellular response to stress
1.25	8.95e-03	GO:0016265	death
1.81	9.78e-03	GO:0021915	neural tube development
1.40	1.04e-02	GO:0045597	positive regulation of cell differentiation
1.33	1.38e-02	GO:0048646	anatomical structure formation involved in morphogenesis
1.10	1.53e-02	GO:0051716	cellular response to stimulus
1.51	1.65e-02	GO:0032582	negative regulation of gene-specific transcription
1.25	1.69e-02	GO:0046907	intracellular transport
2.36	1.74e-02	GO:0010717	regulation of epithelial to mesenchymal transition
1.92	1.91e-02	GO:0001838	embryonic epithelial tube formation
2.10	1.93e-02	GO:0030177	positive regulation of Wnt receptor signaling pathway
1.76	2.15e-02	GO:0060828	regulation of canonical Wnt receptor signaling pathway
1.32	2.56e-02	GO:0072358	cardiovascular system development
1.32	2.56e-02	GO:0072359	circulatory system development
1.37	2.72e-02	GO:0007420	brain development
1.10	2.75e-02	GO:0023052	signaling
1.42	2.87e-02	GO:0010608	posttranscriptional regulation of gene expression
1.26	2.98e-02	GO:0006915	apoptosis
1.25	3.10e-02	GO:0016192	vesicle-mediated transport
1.46	3.18e-02	GO:0048011	nerve growth factor receptor signaling pathway
1.40	3.25e-02	GO:0051130	positive regulation of cellular component organization
1.20	3.26e-02	GO:0051649	establishment of localization in cell
1.36	3.27e-02	GO:0090066	regulation of anatomical structure size
1.89	3.31e-02	GO:0072175	epithelial tube formation
1.57	3.47e-02	GO:0051099	positive regulation of binding
1.12	3.52e-02	GO:0019538	protein metabolic process
1.35	3.62e-02	GO:0007264	small GTPase mediated signal transduction
1.45	3.74e-02	GO:0003002	regionalization
1.25	3.84e-02	GO:2000026	regulation of multicellular organismal development
1.12	4.03e-02	GO:0051234	establishment of localization
1.37	4.37e-02	GO:0032535	regulation of cellular component size
2.23	4.56e-02	GO:0090263	positive regulation of canonical Wnt receptor signaling pathway

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.12	6.88e-46	GO:0044424	intracellular part
1.12	5.82e-45	GO:0005622	intracellular
1.13	2.53e-32	GO:0043226	organelle
1.13	8.67e-32	GO:0043229	intracellular organelle
1.15	6.10e-31	GO:0005737	cytoplasm
1.14	1.35e-30	GO:0043227	membrane-bounded organelle
1.14	4.71e-30	GO:0043231	intracellular membrane-bounded organelle
1.18	1.39e-21	GO:0005634	nucleus
1.16	2.64e-19	GO:0044444	cytoplasmic part
1.16	1.87e-18	GO:0044446	intracellular organelle part
1.16	4.96e-18	GO:0044422	organelle part
1.28	1.47e-15	GO:0044428	nuclear part
1.04	1.35e-12	GO:0044464	cell part
1.04	1.51e-12	GO:0005623	cell
1.27	3.40e-12	GO:0031981	nuclear lumen
1.23	6.42e-11	GO:0070013	intracellular organelle lumen
1.24	1.23e-10	GO:0005829	cytosol
1.22	6.80e-10	GO:0043233	organelle lumen
1.21	1.01e-09	GO:0031974	membrane-enclosed lumen
1.29	1.51e-09	GO:0005654	nucleoplasm
1.77	3.75e-07	GO:0005912	adherens junction
1.34	9.22e-07	GO:0044451	nucleoplasm part
1.70	2.40e-06	GO:0070161	anchoring junction
1.15	1.24e-05	GO:0043234	protein complex
1.17	1.71e-05	GO:0031090	organelle membrane
1.18	5.36e-04	GO:0012505	endomembrane system
1.11	1.11e-03	GO:0032991	macromolecular complex
1.22	1.47e-03	GO:0005794	Golgi apparatus
1.44	2.38e-03	GO:0005667	transcription factor complex
1.87	3.76e-03	GO:0031256	leading edge membrane
1.68	4.58e-03	GO:0005925	focal adhesion
1.66	5.02e-03	GO:0005924	cell-substrate adherens junction
1.49	6.36e-03	GO:0031252	cell leading edge
1.25	6.91e-03	GO:0015630	microtubule cytoskeleton
1.63	9.03e-03	GO:0030055	cell-substrate junction
1.45	1.25e-02	GO:0005911	cell-cell junction
1.26	1.63e-02	GO:0044431	Golgi apparatus part
1.11	1.90e-02	GO:0043228	non-membrane-bounded organelle
1.11	1.90e-02	GO:0043232	intracellular non-membrane-bounded organelle
1.32	3.29e-02	GO:0048471	perinuclear region of cytoplasm
1.83	3.62e-02	GO:0031901	early endosome membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.16	8.89e-29	GO:0005515	protein binding
1.09	6.08e-26	GO:0005488	binding
1.17	8.93e-10	GO:0003676	nucleic acid binding
1.21	3.06e-09	GO:0003677	DNA binding
1.59	3.79e-08	GO:0008134	transcription factor binding
1.20	1.02e-07	GO:0000166	nucleotide binding
1.56	1.20e-07	GO:0016564	transcription repressor activity
1.30	3.64e-07	GO:0030528	transcription regulator activity
1.45	6.53e-07	GO:0019904	protein domain specific binding
1.19	1.25e-05	GO:0017076	purine nucleotide binding
1.20	1.28e-05	GO:0016740	transferase activity
1.27	1.97e-05	GO:0001071	nucleic acid binding transcription factor activity
1.27	1.97e-05	GO:0003700	sequence-specific DNA binding transcription factor activity
1.19	2.70e-05	GO:0032553	ribonucleotide binding
1.19	2.70e-05	GO:0032555	purine ribonucleotide binding
1.47	3.51e-05	GO:0016563	transcription activator activity
1.27	4.05e-05	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.19	4.92e-05	GO:0035639	purine ribonucleoside triphosphate binding
1.30	4.98e-05	GO:0016301	kinase activity
1.20	7.68e-05	GO:0030554	adenyl nucleotide binding
1.57	1.48e-04	GO:0010843	promoter binding
1.20	1.54e-04	GO:0032559	adenyl ribonucleotide binding
1.19	3.19e-04	GO:0005524	ATP binding
1.28	3.27e-04	GO:0019899	enzyme binding
1.54	3.78e-04	GO:0000975	regulatory region DNA binding
1.54	3.78e-04	GO:0001067	regulatory region nucleic acid binding
1.54	3.78e-04	GO:0044212	transcription regulatory region DNA binding
1.28	4.55e-04	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.28	1.15e-03	GO:0043565	sequence-specific DNA binding
1.08	3.28e-03	GO:0003824	catalytic activity
1.76	6.04e-03	GO:0003705	sequence-specific enhancer binding RNA polymerase II transcription factor activity
1.54	6.40e-03	GO:0004721	phosphoprotein phosphatase activity
1.32	9.04e-03	GO:0004674	protein serine/threonine kinase activity
1.27	1.06e-02	GO:0004672	protein kinase activity
1.69	1.39e-02	GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity
1.28	1.89e-02	GO:0008092	cytoskeletal protein binding
1.89	2.24e-02	GO:0008301	DNA bending activity
1.46	3.06e-02	GO:0043566	structure-specific DNA binding
1.40	4.00e-02	GO:0016791	phosphatase activity
1.13	4.18e-02	GO:0008270	zinc ion binding