Motif ID: TFDP1.p2

Z-value: 1.841


Transcription factors associated with TFDP1.p2:

Gene SymbolEntrez IDGene Name
TFDP1 7027 transcription factor Dp-1



Activity profile for motif TFDP1.p2.

activity profile for motif TFDP1.p2


Sorted Z-values histogram for motif TFDP1.p2

Sorted Z-values for motif TFDP1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFDP1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_99401543 7.542 NM_001100426
NM_001100427
NM_001100428
NM_001100429
NM_001100430
NM_021159
RAP1GDS1





RAP1, GTP-GDP dissociation stimulator 1





chr12_+_6907646 7.011 NM_001940
ATN1
atrophin 1
chr17_+_57909979 6.287 NM_001112707
NM_006852
TLK2

tousled-like kinase 2

chr12_-_61283474 6.072 NM_175895
C12orf61
chromosome 12 open reading frame 61
chr22_+_27609889 5.726 NM_032173
ZNRF3
zinc and ring finger 3
chr1_+_224317030 5.154 H3F3A
H3 histone, family 3A
chr16_+_51722285 5.137 CHD9
chromodomain helicase DNA binding protein 9
chr9_+_130354490 5.108 NM_001130438
NM_001195532
NM_003127
SPTAN1


spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)


chr1_+_224317044 5.043 H3F3A
LOC440926
H3 histone, family 3A
H3 histone, family 3A pseudogene
chr11_+_12652427 4.969 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr5_+_139473873 4.951 NM_005859
PURA
purine-rich element binding protein A
chr6_+_163756187 4.890 QKI
quaking homolog, KH domain RNA binding (mouse)
chr1_+_224317056 4.747 H3F3A
LOC440926
H3 histone, family 3A
H3 histone, family 3A pseudogene
chr1_+_224317036 4.744 NM_002107
H3F3A
H3 histone, family 3A
chr1_+_224317062 4.620 H3F3A
LOC440926
H3 histone, family 3A
H3 histone, family 3A pseudogene
chr2_+_159533329 4.451 NM_001145909
NM_033394
TANC1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr10_+_23768203 4.439 NM_001145373
OTUD1
OTU domain containing 1
chr1_+_26671548 4.417 HMGN2
high-mobility group nucleosomal binding domain 2
chr7_+_137795719 4.406 TRIM24
tripartite motif containing 24
chr11_+_110978309 4.383 NM_015191
SIK2
salt-inducible kinase 2
chr6_+_127629677 4.371 NM_030963
RNF146
ring finger protein 146
chr2_+_85051687 4.315 NM_020122
KCMF1
potassium channel modulatory factor 1
chr3_+_43303005 4.261 NM_001100594
NM_017719
SNRK

SNF related kinase

chr2_+_149119029 4.236 NM_015630
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr3_+_112273464 4.176 NM_015480
PVRL3
poliovirus receptor-related 3
chr1_+_26895108 4.133 NM_006015
NM_139135
ARID1A

AT rich interactive domain 1A (SWI-like)

chr13_-_109236897 4.078 NM_003749
IRS2
insulin receptor substrate 2
chr15_-_58671929 4.067 NM_134262
RORA
RAR-related orphan receptor A
chr3_+_112273352 4.066 PVRL3
poliovirus receptor-related 3
chr8_+_30361485 3.997 NM_001008710
NM_001008711
NM_001008712
NM_006867
RBPMS



RNA binding protein with multiple splicing



chr3_-_15875932 3.978 NM_015199
ANKRD28
ankyrin repeat domain 28
chr2_+_42249896 3.924 NM_001145076
NM_019063
EML4

echinoderm microtubule associated protein like 4

chr12_+_50271283 3.883 NM_014191
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr2_+_149118791 3.850 EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr3_+_180348818 3.849 NM_006218
PIK3CA
phosphoinositide-3-kinase, catalytic, alpha polypeptide
chr2_+_85051942 3.763 KCMF1
potassium channel modulatory factor 1
chr1_+_26896519 3.741 ARID1A
AT rich interactive domain 1A (SWI-like)
chr21_+_16024241 3.709 NM_013396
USP25
ubiquitin specific peptidase 25
chr20_+_41519882 3.709 NM_006275
SRSF6
serine/arginine-rich splicing factor 6
chr14_+_61231795 3.679 NM_001530
NM_181054
HIF1A

hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

chr2_+_36436316 3.674 CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr14_+_59785723 3.647 PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr16_+_21926939 3.611 NM_001164579
C16orf52
chromosome 16 open reading frame 52
chr10_+_22649977 3.574 NM_005180
BMI1
BMI1 polycomb ring finger oncogene
chr8_+_81560971 3.561 NM_001105539
NM_023929
ZBTB10

zinc finger and BTB domain containing 10

chr17_+_31975611 3.549 GGNBP2
gametogenetin binding protein 2
chr2_+_181553783 3.547 UBE2E3
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr3_+_58452560 3.499 NM_001128214
KCTD6
potassium channel tetramerisation domain containing 6
chr1_+_25629968 3.438 NM_018202
TMEM57
transmembrane protein 57
chr14_+_59786047 3.428 PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr17_+_59053518 3.384 NM_002401
NM_203351
MAP3K3

mitogen-activated protein kinase kinase kinase 3

chr7_+_116099648 3.382 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr3_-_88190737 3.349 NM_001008390
NM_003663
CGGBP1

CGG triplet repeat binding protein 1

chr2_+_181553613 3.319 UBE2E3
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr10_+_49184658 3.313 MAPK8
mitogen-activated protein kinase 8
chr1_+_196392513 3.268 NM_133494
NEK7
NIMA (never in mitosis gene a)-related kinase 7
chr1_+_144188375 3.246 NM_153713
LIX1L
Lix1 homolog (mouse)-like
chr5_+_122875691 3.239 NM_001031812
NM_001044722
NM_001044723
NM_004384
CSNK1G3



casein kinase 1, gamma 3



chr2_-_160972606 3.239 RBMS1
RNA binding motif, single stranded interacting protein 1
chr3_+_173240983 3.123 NM_001135095
FNDC3B
fibronectin type III domain containing 3B
chr9_+_107046713 3.104 NM_080546
SLC44A1
solute carrier family 44, member 1
chr17_+_59053515 3.097 MAP3K3
mitogen-activated protein kinase kinase kinase 3
chr7_+_77004686 3.077 NM_002835
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr2_+_191222077 3.076 NM_005966
NAB1
NGFI-A binding protein 1 (EGR1 binding protein 1)
chr2_+_203901160 3.067 NM_005759
ABI2
abl-interactor 2
chr2_+_181553333 3.065 NM_182678
NM_006357
UBE2E3

ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)

chr11_+_34030500 3.064 CAPRIN1
cell cycle associated protein 1
chr10_+_35665614 3.011 NM_145012
CCNY
cyclin Y
chr6_+_157140895 3.005


chr15_+_97923702 2.998 MEF2A
myocyte enhancer factor 2A
chr14_+_31616196 2.972 NM_001030055
NM_001173
ARHGAP5

Rho GTPase activating protein 5

chr6_-_151754337 2.958 NM_020861
ZBTB2
zinc finger and BTB domain containing 2
chr4_+_89147821 2.908 NM_000297
PKD2
polycystic kidney disease 2 (autosomal dominant)
chr20_+_41519947 2.902 SRSF6
serine/arginine-rich splicing factor 6
chr7_+_17304707 2.883 NM_001621
AHR
aryl hydrocarbon receptor
chr1_+_90233238 2.864 NM_182975
NM_182976
ZNF326

zinc finger protein 326

chr14_+_59785739 2.818 PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr9_+_129414287 2.786 NM_001032221
NM_003165
STXBP1

syntaxin binding protein 1

chr18_-_12874140 2.753 NM_002828
NM_080422
NM_080423
PTPN2


protein tyrosine phosphatase, non-receptor type 2


chr8_-_12657339 2.752 NM_152271
LONRF1
LON peptidase N-terminal domain and ring finger 1
chr22_+_49459935 2.711 NM_001080420
SHANK3
SH3 and multiple ankyrin repeat domains 3
chr9_+_107046758 2.693 SLC44A1
solute carrier family 44, member 1
chr20_+_13924263 2.683 MACROD2
MACRO domain containing 2
chr18_-_44189625 2.664 ZBTB7C
zinc finger and BTB domain containing 7C
chr10_+_105716925 2.660 SLK
STE20-like kinase
chr17_+_24742068 2.656 NM_020791
TAOK1
TAO kinase 1
chr6_+_167970334 2.639 NM_001040000
MLLT4
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
chr1_+_6767968 2.634 NM_001195563
NM_015215
CAMTA1

calmodulin binding transcription activator 1

chr10_+_112669349 2.628 SHOC2
soc-2 suppressor of clear homolog (C. elegans)
chr17_+_59053447 2.614 MAP3K3
mitogen-activated protein kinase kinase kinase 3
chr10_+_22650145 2.612 BMI1
BMI1 polycomb ring finger oncogene
chr5_+_126881207 2.598 NM_130809
PRRC1
proline-rich coiled-coil 1
chr14_+_99507848 2.585 EVL
Enah/Vasp-like
chr4_+_38341982 2.584 NM_016531
KLF3
Kruppel-like factor 3 (basic)
chr17_+_31974849 2.567 NM_024835
GGNBP2
gametogenetin binding protein 2
chr14_+_59785703 2.556 NM_021003
NM_177951
PPM1A

protein phosphatase, Mg2+/Mn2+ dependent, 1A

chr1_+_177261678 2.549 NM_014864
FAM20B
family with sequence similarity 20, member B
chr13_+_96884682 2.543 RAP2A
RAP2A, member of RAS oncogene family
chr18_-_72336133 2.538 NM_014643
ZNF516
zinc finger protein 516
chr11_+_34030465 2.530 CAPRIN1
cell cycle associated protein 1
chr10_+_120779217 2.517 NM_199461
NANOS1
nanos homolog 1 (Drosophila)
chr3_+_134775404 2.513 CDV3
CDV3 homolog (mouse)
chr6_+_4721640 2.500 NM_004824
CDYL
chromodomain protein, Y-like
chr4_+_129951877 2.493 PHF17
PHD finger protein 17
chr6_+_157140954 2.489 ARID1B
AT rich interactive domain 1B (SWI1-like)
chr1_+_24944493 2.476 CLIC4
chloride intracellular channel 4
chr20_-_51644187 2.471 ZNF217
zinc finger protein 217
chr15_+_54998181 2.460 TCF12
transcription factor 12
chr1_+_88922424 2.437 NM_006256
PKN2
protein kinase N2
chr14_+_93710401 2.424 NM_020958
NM_058237
PPP4R4

protein phosphatase 4, regulatory subunit 4

chr13_+_34414390 2.422 NM_015678
NBEA
neurobeachin
chr21_+_37661063 2.421 DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr6_+_126153693 2.416 NM_001122842
NM_181782
NCOA7

nuclear receptor coactivator 7

chr10_+_94598204 2.399 NM_019053
EXOC6
exocyst complex component 6
chr16_+_66676833 2.396 NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr9_+_100907222 2.394 NM_001130916
NM_004612
TGFBR1

transforming growth factor, beta receptor 1

chr22_-_32646325 2.385 NM_004737
NM_133642
LARGE

like-glycosyltransferase

chr12_+_105873803 2.374 C12orf23
chromosome 12 open reading frame 23
chr22_+_33983444 2.357 NM_001003681
HMGXB4
HMG box domain containing 4
chr11_-_30564338 2.348 NM_001145399
MPPED2
metallophosphoesterase domain containing 2
chr15_+_71131877 2.329 NM_001172623
NM_001172624
NM_002499
NEO1


neogenin 1


chr8_+_96215273 2.325 PLEKHF2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr1_+_113734997 2.323 NM_001142782
NM_152900
MAGI3

membrane associated guanylate kinase, WW and PDZ domain containing 3

chr14_+_31615922 2.316 ARHGAP5
Rho GTPase activating protein 5
chr9_+_107046811 2.314 SLC44A1
solute carrier family 44, member 1
chr11_+_34030527 2.313 CAPRIN1
cell cycle associated protein 1
chr11_+_32870935 2.311 NM_001076786
QSER1
glutamine and serine rich 1
chr17_+_63252087 2.299 NM_004459
NM_182641
BPTF

bromodomain PHD finger transcription factor

chr9_+_100907189 2.289 TGFBR1
transforming growth factor, beta receptor 1
chr1_+_26671488 2.280 NM_005517
HMGN2
high-mobility group nucleosomal binding domain 2
chr3_+_41215926 2.274 NM_001098209
NM_001098210
NM_001904
CTNNB1


catenin (cadherin-associated protein), beta 1, 88kDa


chr9_+_100907213 2.268 TGFBR1
transforming growth factor, beta receptor 1
chr14_+_31615959 2.257 ARHGAP5
Rho GTPase activating protein 5
chr10_+_59942874 2.257 NM_001080512
BICC1
bicaudal C homolog 1 (Drosophila)
chr3_-_9414122 2.249 LOC440944
hypothetical LOC440944
chr10_+_111757867 2.239 ADD3
adducin 3 (gamma)
chr10_+_86078136 2.225 NM_018999
FAM190B
family with sequence similarity 190, member B
chr9_+_128662756 2.222 NM_001099270
ZBTB34
zinc finger and BTB domain containing 34
chr18_+_46810598 2.217 SMAD4
SMAD family member 4
chr12_-_123023312 2.216 CCDC92
coiled-coil domain containing 92
chr10_+_92970302 2.213 NM_032373
PCGF5
polycomb group ring finger 5
chr6_-_110607496 2.208 WASF1
WAS protein family, member 1
chr13_+_97426713 2.201 IPO5
importin 5
chr9_+_100907292 2.194


chr8_+_87424074 2.190 NM_007013
WWP1
WW domain containing E3 ubiquitin protein ligase 1
chr6_+_163755773 2.186 QKI
quaking homolog, KH domain RNA binding (mouse)
chr3_-_187025438 2.182 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr10_-_11693535 2.180 NM_014688
USP6NL
USP6 N-terminal like
chr2_-_109728958 2.171 NM_144710
NM_178584
SEPT10

septin 10

chr20_-_48980858 2.167 NM_015339
NM_181442
ADNP

activity-dependent neuroprotector homeobox

chr21_+_16024157 2.160 USP25
ubiquitin specific peptidase 25
chr2_-_213724577 2.153 NM_001079526
IKZF2
IKAROS family zinc finger 2 (Helios)
chr4_+_145786622 2.149 NM_022475
HHIP
hedgehog interacting protein
chr15_+_54998264 2.148 TCF12
transcription factor 12
chr1_+_61320213 2.144 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr15_+_83092854 2.136 ZNF592
zinc finger protein 592
chr1_-_93199586 2.128 NM_001006605
FAM69A
family with sequence similarity 69, member A
chr1_+_24944554 2.118 CLIC4
chloride intracellular channel 4
chr6_+_126153750 2.105 NCOA7
nuclear receptor coactivator 7
chr3_-_137953876 2.103 NM_005862
STAG1
stromal antigen 1
chr21_+_37661728 2.095 NM_101395
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr13_+_96884316 2.090 NM_021033
RAP2A
RAP2A, member of RAS oncogene family
chr4_+_26471410 2.082 NM_001169117
NM_001169118
NM_020860
STIM2


stromal interaction molecule 2


chr12_-_54869568 2.072 NM_001130420
NM_003075
NM_139067
SMARCC2


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2


chr5_+_127447306 2.072 NM_001046
SLC12A2
solute carrier family 12 (sodium/potassium/chloride transporters), member 2
chr10_-_62431203 2.071 RHOBTB1
Rho-related BTB domain containing 1
chr22_+_39818553 2.063 NM_001429
EP300
E1A binding protein p300
chr2_+_203208456 2.061 FAM117B
family with sequence similarity 117, member B
chr7_+_120378052 2.060 NM_019071
NM_198267
ING3

inhibitor of growth family, member 3

chr14_+_64949447 2.059 FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr1_+_84316217 2.057 NM_002731
NM_207578
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr7_-_130069399 2.057 NM_138693
KLF14
Kruppel-like factor 14
chr9_+_115678365 2.056 NM_133374
ZNF618
zinc finger protein 618
chr10_+_76256305 2.047 NM_012330
MYST4
MYST histone acetyltransferase (monocytic leukemia) 4
chr5_+_115205515 2.038 NM_001284
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr7_+_138695537 2.036 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr15_+_83092806 2.032 NM_014630
ZNF592
zinc finger protein 592
chr17_+_43082557 2.030 KPNB1
karyopherin (importin) beta 1
chr2_+_46378405 2.022 EPAS1
endothelial PAS domain protein 1
chr11_+_117812282 2.017 NM_001197104
NM_005933
MLL

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

chr6_+_163755658 2.012 NM_006775
NM_206853
NM_206854
NM_206855
QKI



quaking homolog, KH domain RNA binding (mouse)



chr16_+_68157370 2.009 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr17_-_31974768 1.995 DKFZp564H213
hypothetical LOC440432
chr16_+_67778441 1.995 NM_006750
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr3_-_14964620 1.983


chr6_+_157141565 1.977 ARID1B
AT rich interactive domain 1B (SWI1-like)
chr12_+_8741746 1.937 NM_020734
RIMKLB
ribosomal modification protein rimK-like family member B
chr1_+_177261798 1.925 FAM20B
family with sequence similarity 20, member B
chr2_+_54536780 1.924 NM_003128
SPTBN1
spectrin, beta, non-erythrocytic 1
chr13_+_97593411 1.922 NM_001001715
NM_005766
FARP1

FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)

chr1_+_35507145 1.921 NM_005095
ZMYM4
zinc finger, MYM-type 4
chr1_+_96959762 1.917 NM_021190
PTBP2
polypyrimidine tract binding protein 2
chr1_-_164402575 1.915 NM_001017961
FAM78B
family with sequence similarity 78, member B
chr7_+_24579239 1.904 NM_016447
MPP6
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr9_+_90193058 1.893 NM_006717
SPIN1
spindlin 1
chr6_+_20510019 1.892 NM_001949
E2F3
E2F transcription factor 3
chr2_+_46623396 1.882 RHOQ
ras homolog gene family, member Q
chr3_+_41215999 1.876 CTNNB1
catenin (cadherin-associated protein), beta 1, 88kDa
chr6_+_163755788 1.869 QKI
quaking homolog, KH domain RNA binding (mouse)
chr15_+_83092525 1.862 ZNF592
zinc finger protein 592

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.26 3.32e-36 GO:0044260 cellular macromolecule metabolic process
1.11 4.63e-35 GO:0009987 cellular process
1.19 1.43e-30 GO:0044237 cellular metabolic process
1.20 2.27e-25 GO:0043170 macromolecule metabolic process
1.16 1.96e-23 GO:0044238 primary metabolic process
1.29 2.69e-22 GO:0044267 cellular protein metabolic process
1.33 5.98e-20 GO:0006464 protein modification process
1.26 2.01e-19 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.14 4.14e-19 GO:0008152 metabolic process
1.31 8.10e-18 GO:0043412 macromolecule modification
1.13 1.74e-16 GO:0050794 regulation of cellular process
1.22 3.23e-16 GO:0034641 cellular nitrogen compound metabolic process
1.21 3.48e-16 GO:0031323 regulation of cellular metabolic process
1.25 4.19e-16 GO:0071842 cellular component organization at cellular level
1.21 8.77e-16 GO:0016043 cellular component organization
1.27 1.27e-15 GO:0090304 nucleic acid metabolic process
1.21 1.88e-15 GO:0006807 nitrogen compound metabolic process
1.24 4.10e-15 GO:0071841 cellular component organization or biogenesis at cellular level
1.20 5.12e-15 GO:0071840 cellular component organization or biogenesis
1.20 1.80e-14 GO:0080090 regulation of primary metabolic process
1.32 1.31e-13 GO:0009966 regulation of signal transduction
1.21 2.32e-13 GO:0019538 protein metabolic process
1.30 3.71e-13 GO:0006996 organelle organization
1.11 4.33e-13 GO:0050789 regulation of biological process
1.19 5.31e-13 GO:0060255 regulation of macromolecule metabolic process
1.17 1.14e-12 GO:0019222 regulation of metabolic process
1.27 8.01e-12 GO:0016070 RNA metabolic process
1.22 3.04e-11 GO:0048522 positive regulation of cellular process
1.28 4.54e-11 GO:0023051 regulation of signaling
1.22 7.09e-11 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.10 7.15e-11 GO:0065007 biological regulation
1.27 1.26e-10 GO:0034645 cellular macromolecule biosynthetic process
1.20 1.50e-10 GO:0051171 regulation of nitrogen compound metabolic process
1.22 1.61e-10 GO:0044249 cellular biosynthetic process
1.26 1.81e-10 GO:0009059 macromolecule biosynthetic process
1.20 2.17e-10 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.20 2.17e-10 GO:0031326 regulation of cellular biosynthetic process
1.44 5.66e-10 GO:0051276 chromosome organization
1.35 5.90e-10 GO:0032774 RNA biosynthetic process
1.20 5.96e-10 GO:0009889 regulation of biosynthetic process
1.21 6.57e-10 GO:0009058 biosynthetic process
1.56 1.31e-09 GO:0016568 chromatin modification
1.36 1.60e-09 GO:0006351 transcription, DNA-dependent
1.20 2.06e-09 GO:0010556 regulation of macromolecule biosynthetic process
1.19 3.67e-09 GO:0048518 positive regulation of biological process
1.20 4.19e-09 GO:0010468 regulation of gene expression
1.24 4.44e-09 GO:0010467 gene expression
1.20 1.86e-08 GO:0051252 regulation of RNA metabolic process
1.32 2.06e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.46 3.48e-08 GO:0006325 chromatin organization
1.31 1.02e-07 GO:0006793 phosphorus metabolic process
1.31 1.02e-07 GO:0006796 phosphate metabolic process
1.20 1.13e-07 GO:0048523 negative regulation of cellular process
1.27 2.43e-07 GO:0051641 cellular localization
1.38 3.61e-07 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.24 3.76e-07 GO:0009653 anatomical structure morphogenesis
1.19 4.72e-07 GO:0048519 negative regulation of biological process
1.19 6.82e-07 GO:0006355 regulation of transcription, DNA-dependent
1.29 7.97e-07 GO:0032268 regulation of cellular protein metabolic process
1.33 8.07e-07 GO:0046907 intracellular transport
1.29 9.85e-07 GO:0007049 cell cycle
1.32 1.05e-06 GO:0033554 cellular response to stress
1.27 1.20e-06 GO:0010604 positive regulation of macromolecule metabolic process
1.36 1.37e-06 GO:0031327 negative regulation of cellular biosynthetic process
1.35 1.49e-06 GO:0009890 negative regulation of biosynthetic process
1.30 1.65e-06 GO:0010605 negative regulation of macromolecule metabolic process
1.36 2.39e-06 GO:0010558 negative regulation of macromolecule biosynthetic process
1.29 2.56e-06 GO:0009892 negative regulation of metabolic process
1.30 2.76e-06 GO:0031324 negative regulation of cellular metabolic process
1.33 3.12e-06 GO:0006468 protein phosphorylation
1.32 3.31e-06 GO:0051173 positive regulation of nitrogen compound metabolic process
1.15 3.48e-06 GO:0048856 anatomical structure development
1.13 6.35e-06 GO:0032502 developmental process
1.32 7.81e-06 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22 8.29e-06 GO:0007399 nervous system development
1.25 8.50e-06 GO:0031325 positive regulation of cellular metabolic process
1.48 8.87e-06 GO:0070647 protein modification by small protein conjugation or removal
1.24 1.20e-05 GO:0009893 positive regulation of metabolic process
1.35 2.29e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.34 3.42e-05 GO:0051172 negative regulation of nitrogen compound metabolic process
1.51 3.53e-05 GO:0032446 protein modification by small protein conjugation
1.23 3.66e-05 GO:0033036 macromolecule localization
1.28 3.91e-05 GO:0008219 cell death
1.37 4.13e-05 GO:0044265 cellular macromolecule catabolic process
1.28 4.95e-05 GO:0016265 death
1.29 5.47e-05 GO:0051128 regulation of cellular component organization
1.25 5.73e-05 GO:0051246 regulation of protein metabolic process
1.13 5.74e-05 GO:0007275 multicellular organismal development
1.32 6.03e-05 GO:0051254 positive regulation of RNA metabolic process
1.25 6.33e-05 GO:0051649 establishment of localization in cell
1.33 7.05e-05 GO:0007167 enzyme linked receptor protein signaling pathway
1.14 1.17e-04 GO:0048731 system development
1.33 1.19e-04 GO:0010629 negative regulation of gene expression
1.25 1.22e-04 GO:0008104 protein localization
1.60 1.30e-04 GO:0016570 histone modification
1.59 1.71e-04 GO:0016569 covalent chromatin modification
1.35 1.81e-04 GO:0051253 negative regulation of RNA metabolic process
1.35 1.84e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.50 2.01e-04 GO:0016567 protein ubiquitination
1.46 2.69e-04 GO:0006366 transcription from RNA polymerase II promoter
1.42 3.59e-04 GO:0018193 peptidyl-amino acid modification
1.26 6.35e-04 GO:0031328 positive regulation of cellular biosynthetic process
1.17 6.75e-04 GO:0048583 regulation of response to stimulus
1.26 6.98e-04 GO:0016310 phosphorylation
1.31 1.02e-03 GO:0000902 cell morphogenesis
1.25 1.12e-03 GO:0022008 neurogenesis
1.33 1.19e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.25 1.31e-03 GO:0048468 cell development
1.23 1.33e-03 GO:0010646 regulation of cell communication
1.25 1.39e-03 GO:0009891 positive regulation of biosynthetic process
1.30 1.59e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.12 1.65e-03 GO:0051179 localization
1.29 2.20e-03 GO:0032989 cellular component morphogenesis
1.26 2.55e-03 GO:0031399 regulation of protein modification process
1.29 2.56e-03 GO:0009057 macromolecule catabolic process
1.19 3.17e-03 GO:0035556 intracellular signal transduction
1.25 3.93e-03 GO:0022402 cell cycle process
1.32 4.12e-03 GO:0031175 neuron projection development
1.28 5.48e-03 GO:0030030 cell projection organization
1.39 5.66e-03 GO:0019941 modification-dependent protein catabolic process
1.27 6.29e-03 GO:0010628 positive regulation of gene expression
1.32 6.55e-03 GO:0000904 cell morphogenesis involved in differentiation
1.26 6.66e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.26 7.40e-03 GO:0012501 programmed cell death
1.54 7.55e-03 GO:0006417 regulation of translation
1.32 7.80e-03 GO:0072358 cardiovascular system development
1.32 7.80e-03 GO:0072359 circulatory system development
1.39 7.89e-03 GO:0006511 ubiquitin-dependent protein catabolic process
1.23 8.66e-03 GO:0045184 establishment of protein localization
1.39 9.03e-03 GO:0043632 modification-dependent macromolecule catabolic process
1.35 1.02e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.31 1.05e-02 GO:0034621 cellular macromolecular complex subunit organization
1.23 1.12e-02 GO:0048699 generation of neurons
1.38 1.13e-02 GO:0033043 regulation of organelle organization
1.38 1.14e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
1.25 1.16e-02 GO:0016192 vesicle-mediated transport
1.28 1.39e-02 GO:0006259 DNA metabolic process
1.29 1.40e-02 GO:0016071 mRNA metabolic process
1.10 1.47e-02 GO:0051716 cellular response to stimulus
1.20 1.64e-02 GO:0044248 cellular catabolic process
1.25 1.74e-02 GO:0006915 apoptosis
1.25 2.01e-02 GO:0019220 regulation of phosphate metabolic process
1.25 2.01e-02 GO:0051174 regulation of phosphorus metabolic process
1.33 2.02e-02 GO:0009968 negative regulation of signal transduction
1.40 2.04e-02 GO:0010608 posttranscriptional regulation of gene expression
1.55 2.04e-02 GO:0016311 dephosphorylation
1.27 2.04e-02 GO:0051726 regulation of cell cycle
1.28 2.17e-02 GO:0048666 neuron development
1.35 2.19e-02 GO:0044419 interspecies interaction between organisms
1.29 2.20e-02 GO:0006974 response to DNA damage stimulus
1.23 2.37e-02 GO:0043933 macromolecular complex subunit organization
1.36 2.47e-02 GO:0044257 cellular protein catabolic process
1.29 2.75e-02 GO:0032990 cell part morphogenesis
1.25 2.80e-02 GO:0022403 cell cycle phase
1.31 2.97e-02 GO:0010648 negative regulation of cell communication
1.25 3.12e-02 GO:0042325 regulation of phosphorylation
1.22 3.24e-02 GO:0015031 protein transport
2.59 3.26e-02 GO:0021772 olfactory bulb development
2.59 3.26e-02 GO:0021988 olfactory lobe development
1.27 3.63e-02 GO:0000278 mitotic cell cycle
1.34 3.67e-02 GO:0030163 protein catabolic process
1.31 3.95e-02 GO:0023057 negative regulation of signaling
1.14 4.05e-02 GO:0048869 cellular developmental process
1.21 4.32e-02 GO:0042127 regulation of cell proliferation
1.56 4.40e-02 GO:0030111 regulation of Wnt receptor signaling pathway
1.98 4.43e-02 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.14 3.32e-75 GO:0005622 intracellular
1.15 2.50e-72 GO:0044424 intracellular part
1.17 3.87e-52 GO:0043231 intracellular membrane-bounded organelle
1.17 4.01e-52 GO:0043227 membrane-bounded organelle
1.15 2.72e-51 GO:0043226 organelle
1.15 3.79e-51 GO:0043229 intracellular organelle
1.24 2.76e-46 GO:0005634 nucleus
1.15 4.03e-37 GO:0005737 cytoplasm
1.32 2.11e-24 GO:0044428 nuclear part
1.05 6.11e-22 GO:0005623 cell
1.05 8.73e-22 GO:0044464 cell part
1.17 4.43e-21 GO:0044446 intracellular organelle part
1.33 5.49e-21 GO:0031981 nuclear lumen
1.29 5.24e-20 GO:0070013 intracellular organelle lumen
1.16 1.78e-19 GO:0044422 organelle part
1.27 9.82e-19 GO:0031974 membrane-enclosed lumen
1.27 1.35e-18 GO:0043233 organelle lumen
1.28 1.91e-17 GO:0005829 cytosol
1.14 2.26e-17 GO:0044444 cytoplasmic part
1.35 8.30e-17 GO:0005654 nucleoplasm
1.43 8.47e-10 GO:0005694 chromosome
1.17 4.99e-08 GO:0043228 non-membrane-bounded organelle
1.17 4.99e-08 GO:0043232 intracellular non-membrane-bounded organelle
1.35 6.27e-08 GO:0044451 nucleoplasm part
1.43 7.70e-08 GO:0044427 chromosomal part
1.14 2.54e-07 GO:0032991 macromolecular complex
1.55 2.49e-06 GO:0000785 chromatin
1.14 5.73e-06 GO:0043234 protein complex
1.59 2.03e-05 GO:0031252 cell leading edge
1.86 4.39e-05 GO:0000790 nuclear chromatin
1.50 2.71e-04 GO:0000228 nuclear chromosome
1.73 1.01e-03 GO:0016585 chromatin remodeling complex
1.52 1.22e-03 GO:0044454 nuclear chromosome part
1.16 5.09e-03 GO:0012505 endomembrane system
1.34 5.85e-03 GO:0048471 perinuclear region of cytoplasm
1.77 6.95e-03 GO:0034399 nuclear periphery
1.13 1.41e-02 GO:0031090 organelle membrane
1.27 1.43e-02 GO:0005730 nucleolus
1.49 2.06e-02 GO:0031965 nuclear membrane
1.75 2.60e-02 GO:0016363 nuclear matrix
1.36 3.52e-02 GO:0005635 nuclear envelope
1.31 4.27e-02 GO:0005815 microtubule organizing center
1.48 4.37e-02 GO:0000151 ubiquitin ligase complex
1.87 4.66e-02 GO:0000792 heterochromatin
1.46 4.92e-02 GO:0005912 adherens junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.20 4.25e-49 GO:0005515 protein binding
1.10 1.71e-35 GO:0005488 binding
1.26 5.22e-16 GO:0000166 nucleotide binding
1.18 1.35e-12 GO:0003676 nucleic acid binding
1.36 3.74e-11 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.24 6.41e-11 GO:0035639 purine ribonucleoside triphosphate binding
1.23 1.81e-10 GO:0017076 purine nucleotide binding
1.24 1.99e-10 GO:0032553 ribonucleotide binding
1.24 1.99e-10 GO:0032555 purine ribonucleotide binding
1.33 3.24e-10 GO:0030528 transcription regulator activity
1.36 1.71e-09 GO:0016301 kinase activity
1.36 1.01e-08 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.19 1.54e-08 GO:0003677 DNA binding
1.24 3.34e-08 GO:0030554 adenyl nucleotide binding
1.24 4.33e-08 GO:0005524 ATP binding
1.24 4.84e-08 GO:0032559 adenyl ribonucleotide binding
1.35 1.25e-07 GO:0043565 sequence-specific DNA binding
1.47 2.06e-07 GO:0000988 protein binding transcription factor activity
1.47 2.06e-07 GO:0000989 transcription factor binding transcription factor activity
1.47 3.07e-07 GO:0003712 transcription cofactor activity
1.37 3.09e-07 GO:0004672 protein kinase activity
1.21 8.62e-07 GO:0016740 transferase activity
1.30 2.01e-06 GO:0003723 RNA binding
1.31 2.60e-06 GO:0019899 enzyme binding
1.41 2.86e-06 GO:0019904 protein domain specific binding
1.40 5.70e-06 GO:0004674 protein serine/threonine kinase activity
1.49 2.72e-05 GO:0016881 acid-amino acid ligase activity
1.45 5.85e-05 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.52 7.43e-05 GO:0003713 transcription coactivator activity
1.61 1.09e-04 GO:0004721 phosphoprotein phosphatase activity
1.24 1.58e-04 GO:0001071 nucleic acid binding transcription factor activity
1.24 1.58e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.34 2.84e-04 GO:0016874 ligase activity
1.47 6.69e-04 GO:0019787 small conjugating protein ligase activity
1.41 8.28e-04 GO:0008134 transcription factor binding
1.45 9.83e-04 GO:0016791 phosphatase activity
1.39 1.14e-03 GO:0016563 transcription activator activity
1.31 3.62e-03 GO:0030695 GTPase regulator activity
1.45 3.81e-03 GO:0004842 ubiquitin-protein ligase activity
1.30 4.96e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.47 5.12e-03 GO:0010843 promoter binding
1.45 6.39e-03 GO:0000975 regulatory region DNA binding
1.45 6.39e-03 GO:0001067 regulatory region nucleic acid binding
1.45 6.39e-03 GO:0044212 transcription regulatory region DNA binding
1.08 9.54e-03 GO:0003824 catalytic activity
1.36 1.05e-02 GO:0016564 transcription repressor activity
1.46 1.07e-02 GO:0003682 chromatin binding
1.23 1.46e-02 GO:0042802 identical protein binding
1.26 2.27e-02 GO:0008092 cytoskeletal protein binding
1.19 4.22e-02 GO:0030234 enzyme regulator activity
1.89 4.58e-02 GO:0046332 SMAD binding
1.29 4.81e-02 GO:0008047 enzyme activator activity