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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: TFDP1.p2

Z-value: 1.841

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_+_99401543	7.542	NM_001100426 NM_001100427 NM_001100428 NM_001100429 NM_001100430 NM_021159	RAP1GDS1	RAP1, GTP-GDP dissociation stimulator 1
chr12_+_6907646	7.011	NM_001940	ATN1	atrophin 1
chr17_+_57909979	6.287	NM_001112707 NM_006852	TLK2	tousled-like kinase 2
chr12_-_61283474	6.072	NM_175895	C12orf61	chromosome 12 open reading frame 61
chr22_+_27609889	5.726	NM_032173	ZNRF3	zinc and ring finger 3
chr1_+_224317030	5.154		H3F3A	H3 histone, family 3A
chr16_+_51722285	5.137		CHD9	chromodomain helicase DNA binding protein 9
chr9_+_130354490	5.108	NM_001130438 NM_001195532 NM_003127	SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
chr1_+_224317044	5.043		H3F3A LOC440926	H3 histone, family 3A H3 histone, family 3A pseudogene
chr11_+_12652427	4.969	NM_021961	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr5_+_139473873	4.951	NM_005859	PURA	purine-rich element binding protein A
chr6_+_163756187	4.890		QKI	quaking homolog, KH domain RNA binding (mouse)
chr1_+_224317056	4.747		H3F3A LOC440926	H3 histone, family 3A H3 histone, family 3A pseudogene
chr1_+_224317036	4.744	NM_002107	H3F3A	H3 histone, family 3A
chr1_+_224317062	4.620		H3F3A LOC440926	H3 histone, family 3A H3 histone, family 3A pseudogene
chr2_+_159533329	4.451	NM_001145909 NM_033394	TANC1	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr10_+_23768203	4.439	NM_001145373	OTUD1	OTU domain containing 1
chr1_+_26671548	4.417		HMGN2	high-mobility group nucleosomal binding domain 2
chr7_+_137795719	4.406		TRIM24	tripartite motif containing 24
chr11_+_110978309	4.383	NM_015191	SIK2	salt-inducible kinase 2
chr6_+_127629677	4.371	NM_030963	RNF146	ring finger protein 146
chr2_+_85051687	4.315	NM_020122	KCMF1	potassium channel modulatory factor 1
chr3_+_43303005	4.261	NM_001100594 NM_017719	SNRK	SNF related kinase
chr2_+_149119029	4.236	NM_015630	EPC2	enhancer of polycomb homolog 2 (Drosophila)
chr3_+_112273464	4.176	NM_015480	PVRL3	poliovirus receptor-related 3
chr1_+_26895108	4.133	NM_006015 NM_139135	ARID1A	AT rich interactive domain 1A (SWI-like)
chr13_-_109236897	4.078	NM_003749	IRS2	insulin receptor substrate 2
chr15_-_58671929	4.067	NM_134262	RORA	RAR-related orphan receptor A
chr3_+_112273352	4.066		PVRL3	poliovirus receptor-related 3
chr8_+_30361485	3.997	NM_001008710 NM_001008711 NM_001008712 NM_006867	RBPMS	RNA binding protein with multiple splicing
chr3_-_15875932	3.978	NM_015199	ANKRD28	ankyrin repeat domain 28
chr2_+_42249896	3.924	NM_001145076 NM_019063	EML4	echinoderm microtubule associated protein like 4
chr12_+_50271283	3.883	NM_014191	SCN8A	sodium channel, voltage gated, type VIII, alpha subunit
chr2_+_149118791	3.850		EPC2	enhancer of polycomb homolog 2 (Drosophila)
chr3_+_180348818	3.849	NM_006218	PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide
chr2_+_85051942	3.763		KCMF1	potassium channel modulatory factor 1
chr1_+_26896519	3.741		ARID1A	AT rich interactive domain 1A (SWI-like)
chr21_+_16024241	3.709	NM_013396	USP25	ubiquitin specific peptidase 25
chr20_+_41519882	3.709	NM_006275	SRSF6	serine/arginine-rich splicing factor 6
chr14_+_61231795	3.679	NM_001530 NM_181054	HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr2_+_36436316	3.674		CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr14_+_59785723	3.647		PPM1A	protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr16_+_21926939	3.611	NM_001164579	C16orf52	chromosome 16 open reading frame 52
chr10_+_22649977	3.574	NM_005180	BMI1	BMI1 polycomb ring finger oncogene
chr8_+_81560971	3.561	NM_001105539 NM_023929	ZBTB10	zinc finger and BTB domain containing 10
chr17_+_31975611	3.549		GGNBP2	gametogenetin binding protein 2
chr2_+_181553783	3.547		UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr3_+_58452560	3.499	NM_001128214	KCTD6	potassium channel tetramerisation domain containing 6
chr1_+_25629968	3.438	NM_018202	TMEM57	transmembrane protein 57
chr14_+_59786047	3.428		PPM1A	protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr17_+_59053518	3.384	NM_002401 NM_203351	MAP3K3	mitogen-activated protein kinase kinase kinase 3
chr7_+_116099648	3.382	NM_000245 NM_001127500	MET	met proto-oncogene (hepatocyte growth factor receptor)
chr3_-_88190737	3.349	NM_001008390 NM_003663	CGGBP1	CGG triplet repeat binding protein 1
chr2_+_181553613	3.319		UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr10_+_49184658	3.313		MAPK8	mitogen-activated protein kinase 8
chr1_+_196392513	3.268	NM_133494	NEK7	NIMA (never in mitosis gene a)-related kinase 7
chr1_+_144188375	3.246	NM_153713	LIX1L	Lix1 homolog (mouse)-like
chr5_+_122875691	3.239	NM_001031812 NM_001044722 NM_001044723 NM_004384	CSNK1G3	casein kinase 1, gamma 3
chr2_-_160972606	3.239		RBMS1	RNA binding motif, single stranded interacting protein 1
chr3_+_173240983	3.123	NM_001135095	FNDC3B	fibronectin type III domain containing 3B
chr9_+_107046713	3.104	NM_080546	SLC44A1	solute carrier family 44, member 1
chr17_+_59053515	3.097		MAP3K3	mitogen-activated protein kinase kinase kinase 3
chr7_+_77004686	3.077	NM_002835	PTPN12	protein tyrosine phosphatase, non-receptor type 12
chr2_+_191222077	3.076	NM_005966	NAB1	NGFI-A binding protein 1 (EGR1 binding protein 1)
chr2_+_203901160	3.067	NM_005759	ABI2	abl-interactor 2
chr2_+_181553333	3.065	NM_182678 NM_006357	UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr11_+_34030500	3.064		CAPRIN1	cell cycle associated protein 1
chr10_+_35665614	3.011	NM_145012	CCNY	cyclin Y
chr6_+_157140895	3.005
chr15_+_97923702	2.998		MEF2A	myocyte enhancer factor 2A
chr14_+_31616196	2.972	NM_001030055 NM_001173	ARHGAP5	Rho GTPase activating protein 5
chr6_-_151754337	2.958	NM_020861	ZBTB2	zinc finger and BTB domain containing 2
chr4_+_89147821	2.908	NM_000297	PKD2	polycystic kidney disease 2 (autosomal dominant)
chr20_+_41519947	2.902		SRSF6	serine/arginine-rich splicing factor 6
chr7_+_17304707	2.883	NM_001621	AHR	aryl hydrocarbon receptor
chr1_+_90233238	2.864	NM_182975 NM_182976	ZNF326	zinc finger protein 326
chr14_+_59785739	2.818		PPM1A	protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr9_+_129414287	2.786	NM_001032221 NM_003165	STXBP1	syntaxin binding protein 1
chr18_-_12874140	2.753	NM_002828 NM_080422 NM_080423	PTPN2	protein tyrosine phosphatase, non-receptor type 2
chr8_-_12657339	2.752	NM_152271	LONRF1	LON peptidase N-terminal domain and ring finger 1
chr22_+_49459935	2.711	NM_001080420	SHANK3	SH3 and multiple ankyrin repeat domains 3
chr9_+_107046758	2.693		SLC44A1	solute carrier family 44, member 1
chr20_+_13924263	2.683		MACROD2	MACRO domain containing 2
chr18_-_44189625	2.664		ZBTB7C	zinc finger and BTB domain containing 7C
chr10_+_105716925	2.660		SLK	STE20-like kinase
chr17_+_24742068	2.656	NM_020791	TAOK1	TAO kinase 1
chr6_+_167970334	2.639	NM_001040000	MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
chr1_+_6767968	2.634	NM_001195563 NM_015215	CAMTA1	calmodulin binding transcription activator 1
chr10_+_112669349	2.628		SHOC2	soc-2 suppressor of clear homolog (C. elegans)
chr17_+_59053447	2.614		MAP3K3	mitogen-activated protein kinase kinase kinase 3
chr10_+_22650145	2.612		BMI1	BMI1 polycomb ring finger oncogene
chr5_+_126881207	2.598	NM_130809	PRRC1	proline-rich coiled-coil 1
chr14_+_99507848	2.585		EVL	Enah/Vasp-like
chr4_+_38341982	2.584	NM_016531	KLF3	Kruppel-like factor 3 (basic)
chr17_+_31974849	2.567	NM_024835	GGNBP2	gametogenetin binding protein 2
chr14_+_59785703	2.556	NM_021003 NM_177951	PPM1A	protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr1_+_177261678	2.549	NM_014864	FAM20B	family with sequence similarity 20, member B
chr13_+_96884682	2.543		RAP2A	RAP2A, member of RAS oncogene family
chr18_-_72336133	2.538	NM_014643	ZNF516	zinc finger protein 516
chr11_+_34030465	2.530		CAPRIN1	cell cycle associated protein 1
chr10_+_120779217	2.517	NM_199461	NANOS1	nanos homolog 1 (Drosophila)
chr3_+_134775404	2.513		CDV3	CDV3 homolog (mouse)
chr6_+_4721640	2.500	NM_004824	CDYL	chromodomain protein, Y-like
chr4_+_129951877	2.493		PHF17	PHD finger protein 17
chr6_+_157140954	2.489		ARID1B	AT rich interactive domain 1B (SWI1-like)
chr1_+_24944493	2.476		CLIC4	chloride intracellular channel 4
chr20_-_51644187	2.471		ZNF217	zinc finger protein 217
chr15_+_54998181	2.460		TCF12	transcription factor 12
chr1_+_88922424	2.437	NM_006256	PKN2	protein kinase N2
chr14_+_93710401	2.424	NM_020958 NM_058237	PPP4R4	protein phosphatase 4, regulatory subunit 4
chr13_+_34414390	2.422	NM_015678	NBEA	neurobeachin
chr21_+_37661063	2.421		DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr6_+_126153693	2.416	NM_001122842 NM_181782	NCOA7	nuclear receptor coactivator 7
chr10_+_94598204	2.399	NM_019053	EXOC6	exocyst complex component 6
chr16_+_66676833	2.396		NFATC3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr9_+_100907222	2.394	NM_001130916 NM_004612	TGFBR1	transforming growth factor, beta receptor 1
chr22_-_32646325	2.385	NM_004737 NM_133642	LARGE	like-glycosyltransferase
chr12_+_105873803	2.374		C12orf23	chromosome 12 open reading frame 23
chr22_+_33983444	2.357	NM_001003681	HMGXB4	HMG box domain containing 4
chr11_-_30564338	2.348	NM_001145399	MPPED2	metallophosphoesterase domain containing 2
chr15_+_71131877	2.329	NM_001172623 NM_001172624 NM_002499	NEO1	neogenin 1
chr8_+_96215273	2.325		PLEKHF2	pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr1_+_113734997	2.323	NM_001142782 NM_152900	MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3
chr14_+_31615922	2.316		ARHGAP5	Rho GTPase activating protein 5
chr9_+_107046811	2.314		SLC44A1	solute carrier family 44, member 1
chr11_+_34030527	2.313		CAPRIN1	cell cycle associated protein 1
chr11_+_32870935	2.311	NM_001076786	QSER1	glutamine and serine rich 1
chr17_+_63252087	2.299	NM_004459 NM_182641	BPTF	bromodomain PHD finger transcription factor
chr9_+_100907189	2.289		TGFBR1	transforming growth factor, beta receptor 1
chr1_+_26671488	2.280	NM_005517	HMGN2	high-mobility group nucleosomal binding domain 2
chr3_+_41215926	2.274	NM_001098209 NM_001098210 NM_001904	CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa
chr9_+_100907213	2.268		TGFBR1	transforming growth factor, beta receptor 1
chr14_+_31615959	2.257		ARHGAP5	Rho GTPase activating protein 5
chr10_+_59942874	2.257	NM_001080512	BICC1	bicaudal C homolog 1 (Drosophila)
chr3_-_9414122	2.249		LOC440944	hypothetical LOC440944
chr10_+_111757867	2.239		ADD3	adducin 3 (gamma)
chr10_+_86078136	2.225	NM_018999	FAM190B	family with sequence similarity 190, member B
chr9_+_128662756	2.222	NM_001099270	ZBTB34	zinc finger and BTB domain containing 34
chr18_+_46810598	2.217		SMAD4	SMAD family member 4
chr12_-_123023312	2.216		CCDC92	coiled-coil domain containing 92
chr10_+_92970302	2.213	NM_032373	PCGF5	polycomb group ring finger 5
chr6_-_110607496	2.208		WASF1	WAS protein family, member 1
chr13_+_97426713	2.201		IPO5	importin 5
chr9_+_100907292	2.194
chr8_+_87424074	2.190	NM_007013	WWP1	WW domain containing E3 ubiquitin protein ligase 1
chr6_+_163755773	2.186		QKI	quaking homolog, KH domain RNA binding (mouse)
chr3_-_187025438	2.182		IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr10_-_11693535	2.180	NM_014688	USP6NL	USP6 N-terminal like
chr2_-_109728958	2.171	NM_144710 NM_178584	SEPT10	septin 10
chr20_-_48980858	2.167	NM_015339 NM_181442	ADNP	activity-dependent neuroprotector homeobox
chr21_+_16024157	2.160		USP25	ubiquitin specific peptidase 25
chr2_-_213724577	2.153	NM_001079526	IKZF2	IKAROS family zinc finger 2 (Helios)
chr4_+_145786622	2.149	NM_022475	HHIP	hedgehog interacting protein
chr15_+_54998264	2.148		TCF12	transcription factor 12
chr1_+_61320213	2.144	NM_001134673 NM_005595	NFIA	nuclear factor I/A
chr15_+_83092854	2.136		ZNF592	zinc finger protein 592
chr1_-_93199586	2.128	NM_001006605	FAM69A	family with sequence similarity 69, member A
chr1_+_24944554	2.118		CLIC4	chloride intracellular channel 4
chr6_+_126153750	2.105		NCOA7	nuclear receptor coactivator 7
chr3_-_137953876	2.103	NM_005862	STAG1	stromal antigen 1
chr21_+_37661728	2.095	NM_101395	DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr13_+_96884316	2.090	NM_021033	RAP2A	RAP2A, member of RAS oncogene family
chr4_+_26471410	2.082	NM_001169117 NM_001169118 NM_020860	STIM2	stromal interaction molecule 2
chr12_-_54869568	2.072	NM_001130420 NM_003075 NM_139067	SMARCC2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr5_+_127447306	2.072	NM_001046	SLC12A2	solute carrier family 12 (sodium/potassium/chloride transporters), member 2
chr10_-_62431203	2.071		RHOBTB1	Rho-related BTB domain containing 1
chr22_+_39818553	2.063	NM_001429	EP300	E1A binding protein p300
chr2_+_203208456	2.061		FAM117B	family with sequence similarity 117, member B
chr7_+_120378052	2.060	NM_019071 NM_198267	ING3	inhibitor of growth family, member 3
chr14_+_64949447	2.059		FUT8	fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr1_+_84316217	2.057	NM_002731 NM_207578	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr7_-_130069399	2.057	NM_138693	KLF14	Kruppel-like factor 14
chr9_+_115678365	2.056	NM_133374	ZNF618	zinc finger protein 618
chr10_+_76256305	2.047	NM_012330	MYST4	MYST histone acetyltransferase (monocytic leukemia) 4
chr5_+_115205515	2.038	NM_001284	AP3S1	adaptor-related protein complex 3, sigma 1 subunit
chr7_+_138695537	2.036		LUC7L2	LUC7-like 2 (S. cerevisiae)
chr15_+_83092806	2.032	NM_014630	ZNF592	zinc finger protein 592
chr17_+_43082557	2.030		KPNB1	karyopherin (importin) beta 1
chr2_+_46378405	2.022		EPAS1	endothelial PAS domain protein 1
chr11_+_117812282	2.017	NM_001197104 NM_005933	MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
chr6_+_163755658	2.012	NM_006775 NM_206853 NM_206854 NM_206855	QKI	quaking homolog, KH domain RNA binding (mouse)
chr16_+_68157370	2.009		NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive
chr17_-_31974768	1.995		DKFZp564H213	hypothetical LOC440432
chr16_+_67778441	1.995	NM_006750	SNTB2	syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr3_-_14964620	1.983
chr6_+_157141565	1.977		ARID1B	AT rich interactive domain 1B (SWI1-like)
chr12_+_8741746	1.937	NM_020734	RIMKLB	ribosomal modification protein rimK-like family member B
chr1_+_177261798	1.925		FAM20B	family with sequence similarity 20, member B
chr2_+_54536780	1.924	NM_003128	SPTBN1	spectrin, beta, non-erythrocytic 1
chr13_+_97593411	1.922	NM_001001715 NM_005766	FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr1_+_35507145	1.921	NM_005095	ZMYM4	zinc finger, MYM-type 4
chr1_+_96959762	1.917	NM_021190	PTBP2	polypyrimidine tract binding protein 2
chr1_-_164402575	1.915	NM_001017961	FAM78B	family with sequence similarity 78, member B
chr7_+_24579239	1.904	NM_016447	MPP6	membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr9_+_90193058	1.893	NM_006717	SPIN1	spindlin 1
chr6_+_20510019	1.892	NM_001949	E2F3	E2F transcription factor 3
chr2_+_46623396	1.882		RHOQ	ras homolog gene family, member Q
chr3_+_41215999	1.876		CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa
chr6_+_163755788	1.869		QKI	quaking homolog, KH domain RNA binding (mouse)
chr15_+_83092525	1.862		ZNF592	zinc finger protein 592

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.26	3.32e-36	GO:0044260	cellular macromolecule metabolic process
1.11	4.63e-35	GO:0009987	cellular process
1.19	1.43e-30	GO:0044237	cellular metabolic process
1.20	2.27e-25	GO:0043170	macromolecule metabolic process
1.16	1.96e-23	GO:0044238	primary metabolic process
1.29	2.69e-22	GO:0044267	cellular protein metabolic process
1.33	5.98e-20	GO:0006464	protein modification process
1.26	2.01e-19	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.14	4.14e-19	GO:0008152	metabolic process
1.31	8.10e-18	GO:0043412	macromolecule modification
1.13	1.74e-16	GO:0050794	regulation of cellular process
1.22	3.23e-16	GO:0034641	cellular nitrogen compound metabolic process
1.21	3.48e-16	GO:0031323	regulation of cellular metabolic process
1.25	4.19e-16	GO:0071842	cellular component organization at cellular level
1.21	8.77e-16	GO:0016043	cellular component organization
1.27	1.27e-15	GO:0090304	nucleic acid metabolic process
1.21	1.88e-15	GO:0006807	nitrogen compound metabolic process
1.24	4.10e-15	GO:0071841	cellular component organization or biogenesis at cellular level
1.20	5.12e-15	GO:0071840	cellular component organization or biogenesis
1.20	1.80e-14	GO:0080090	regulation of primary metabolic process
1.32	1.31e-13	GO:0009966	regulation of signal transduction
1.21	2.32e-13	GO:0019538	protein metabolic process
1.30	3.71e-13	GO:0006996	organelle organization
1.11	4.33e-13	GO:0050789	regulation of biological process
1.19	5.31e-13	GO:0060255	regulation of macromolecule metabolic process
1.17	1.14e-12	GO:0019222	regulation of metabolic process
1.27	8.01e-12	GO:0016070	RNA metabolic process
1.22	3.04e-11	GO:0048522	positive regulation of cellular process
1.28	4.54e-11	GO:0023051	regulation of signaling
1.22	7.09e-11	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.10	7.15e-11	GO:0065007	biological regulation
1.27	1.26e-10	GO:0034645	cellular macromolecule biosynthetic process
1.20	1.50e-10	GO:0051171	regulation of nitrogen compound metabolic process
1.22	1.61e-10	GO:0044249	cellular biosynthetic process
1.26	1.81e-10	GO:0009059	macromolecule biosynthetic process
1.20	2.17e-10	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.20	2.17e-10	GO:0031326	regulation of cellular biosynthetic process
1.44	5.66e-10	GO:0051276	chromosome organization
1.35	5.90e-10	GO:0032774	RNA biosynthetic process
1.20	5.96e-10	GO:0009889	regulation of biosynthetic process
1.21	6.57e-10	GO:0009058	biosynthetic process
1.56	1.31e-09	GO:0016568	chromatin modification
1.36	1.60e-09	GO:0006351	transcription, DNA-dependent
1.20	2.06e-09	GO:0010556	regulation of macromolecule biosynthetic process
1.19	3.67e-09	GO:0048518	positive regulation of biological process
1.20	4.19e-09	GO:0010468	regulation of gene expression
1.24	4.44e-09	GO:0010467	gene expression
1.20	1.86e-08	GO:0051252	regulation of RNA metabolic process
1.32	2.06e-08	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.46	3.48e-08	GO:0006325	chromatin organization
1.31	1.02e-07	GO:0006793	phosphorus metabolic process
1.31	1.02e-07	GO:0006796	phosphate metabolic process
1.20	1.13e-07	GO:0048523	negative regulation of cellular process
1.27	2.43e-07	GO:0051641	cellular localization
1.38	3.61e-07	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.24	3.76e-07	GO:0009653	anatomical structure morphogenesis
1.19	4.72e-07	GO:0048519	negative regulation of biological process
1.19	6.82e-07	GO:0006355	regulation of transcription, DNA-dependent
1.29	7.97e-07	GO:0032268	regulation of cellular protein metabolic process
1.33	8.07e-07	GO:0046907	intracellular transport
1.29	9.85e-07	GO:0007049	cell cycle
1.32	1.05e-06	GO:0033554	cellular response to stress
1.27	1.20e-06	GO:0010604	positive regulation of macromolecule metabolic process
1.36	1.37e-06	GO:0031327	negative regulation of cellular biosynthetic process
1.35	1.49e-06	GO:0009890	negative regulation of biosynthetic process
1.30	1.65e-06	GO:0010605	negative regulation of macromolecule metabolic process
1.36	2.39e-06	GO:0010558	negative regulation of macromolecule biosynthetic process
1.29	2.56e-06	GO:0009892	negative regulation of metabolic process
1.30	2.76e-06	GO:0031324	negative regulation of cellular metabolic process
1.33	3.12e-06	GO:0006468	protein phosphorylation
1.32	3.31e-06	GO:0051173	positive regulation of nitrogen compound metabolic process
1.15	3.48e-06	GO:0048856	anatomical structure development
1.13	6.35e-06	GO:0032502	developmental process
1.32	7.81e-06	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22	8.29e-06	GO:0007399	nervous system development
1.25	8.50e-06	GO:0031325	positive regulation of cellular metabolic process
1.48	8.87e-06	GO:0070647	protein modification by small protein conjugation or removal
1.24	1.20e-05	GO:0009893	positive regulation of metabolic process
1.35	2.29e-05	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.34	3.42e-05	GO:0051172	negative regulation of nitrogen compound metabolic process
1.51	3.53e-05	GO:0032446	protein modification by small protein conjugation
1.23	3.66e-05	GO:0033036	macromolecule localization
1.28	3.91e-05	GO:0008219	cell death
1.37	4.13e-05	GO:0044265	cellular macromolecule catabolic process
1.28	4.95e-05	GO:0016265	death
1.29	5.47e-05	GO:0051128	regulation of cellular component organization
1.25	5.73e-05	GO:0051246	regulation of protein metabolic process
1.13	5.74e-05	GO:0007275	multicellular organismal development
1.32	6.03e-05	GO:0051254	positive regulation of RNA metabolic process
1.25	6.33e-05	GO:0051649	establishment of localization in cell
1.33	7.05e-05	GO:0007167	enzyme linked receptor protein signaling pathway
1.14	1.17e-04	GO:0048731	system development
1.33	1.19e-04	GO:0010629	negative regulation of gene expression
1.25	1.22e-04	GO:0008104	protein localization
1.60	1.30e-04	GO:0016570	histone modification
1.59	1.71e-04	GO:0016569	covalent chromatin modification
1.35	1.81e-04	GO:0051253	negative regulation of RNA metabolic process
1.35	1.84e-04	GO:0045892	negative regulation of transcription, DNA-dependent
1.50	2.01e-04	GO:0016567	protein ubiquitination
1.46	2.69e-04	GO:0006366	transcription from RNA polymerase II promoter
1.42	3.59e-04	GO:0018193	peptidyl-amino acid modification
1.26	6.35e-04	GO:0031328	positive regulation of cellular biosynthetic process
1.17	6.75e-04	GO:0048583	regulation of response to stimulus
1.26	6.98e-04	GO:0016310	phosphorylation
1.31	1.02e-03	GO:0000902	cell morphogenesis
1.25	1.12e-03	GO:0022008	neurogenesis
1.33	1.19e-03	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.25	1.31e-03	GO:0048468	cell development
1.23	1.33e-03	GO:0010646	regulation of cell communication
1.25	1.39e-03	GO:0009891	positive regulation of biosynthetic process
1.30	1.59e-03	GO:0045893	positive regulation of transcription, DNA-dependent
1.12	1.65e-03	GO:0051179	localization
1.29	2.20e-03	GO:0032989	cellular component morphogenesis
1.26	2.55e-03	GO:0031399	regulation of protein modification process
1.29	2.56e-03	GO:0009057	macromolecule catabolic process
1.19	3.17e-03	GO:0035556	intracellular signal transduction
1.25	3.93e-03	GO:0022402	cell cycle process
1.32	4.12e-03	GO:0031175	neuron projection development
1.28	5.48e-03	GO:0030030	cell projection organization
1.39	5.66e-03	GO:0019941	modification-dependent protein catabolic process
1.27	6.29e-03	GO:0010628	positive regulation of gene expression
1.32	6.55e-03	GO:0000904	cell morphogenesis involved in differentiation
1.26	6.66e-03	GO:0010557	positive regulation of macromolecule biosynthetic process
1.26	7.40e-03	GO:0012501	programmed cell death
1.54	7.55e-03	GO:0006417	regulation of translation
1.32	7.80e-03	GO:0072358	cardiovascular system development
1.32	7.80e-03	GO:0072359	circulatory system development
1.39	7.89e-03	GO:0006511	ubiquitin-dependent protein catabolic process
1.23	8.66e-03	GO:0045184	establishment of protein localization
1.39	9.03e-03	GO:0043632	modification-dependent macromolecule catabolic process
1.35	1.02e-02	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.31	1.05e-02	GO:0034621	cellular macromolecular complex subunit organization
1.23	1.12e-02	GO:0048699	generation of neurons
1.38	1.13e-02	GO:0033043	regulation of organelle organization
1.38	1.14e-02	GO:0051603	proteolysis involved in cellular protein catabolic process
1.25	1.16e-02	GO:0016192	vesicle-mediated transport
1.28	1.39e-02	GO:0006259	DNA metabolic process
1.29	1.40e-02	GO:0016071	mRNA metabolic process
1.10	1.47e-02	GO:0051716	cellular response to stimulus
1.20	1.64e-02	GO:0044248	cellular catabolic process
1.25	1.74e-02	GO:0006915	apoptosis
1.25	2.01e-02	GO:0019220	regulation of phosphate metabolic process
1.25	2.01e-02	GO:0051174	regulation of phosphorus metabolic process
1.33	2.02e-02	GO:0009968	negative regulation of signal transduction
1.40	2.04e-02	GO:0010608	posttranscriptional regulation of gene expression
1.55	2.04e-02	GO:0016311	dephosphorylation
1.27	2.04e-02	GO:0051726	regulation of cell cycle
1.28	2.17e-02	GO:0048666	neuron development
1.35	2.19e-02	GO:0044419	interspecies interaction between organisms
1.29	2.20e-02	GO:0006974	response to DNA damage stimulus
1.23	2.37e-02	GO:0043933	macromolecular complex subunit organization
1.36	2.47e-02	GO:0044257	cellular protein catabolic process
1.29	2.75e-02	GO:0032990	cell part morphogenesis
1.25	2.80e-02	GO:0022403	cell cycle phase
1.31	2.97e-02	GO:0010648	negative regulation of cell communication
1.25	3.12e-02	GO:0042325	regulation of phosphorylation
1.22	3.24e-02	GO:0015031	protein transport
2.59	3.26e-02	GO:0021772	olfactory bulb development
2.59	3.26e-02	GO:0021988	olfactory lobe development
1.27	3.63e-02	GO:0000278	mitotic cell cycle
1.34	3.67e-02	GO:0030163	protein catabolic process
1.31	3.95e-02	GO:0023057	negative regulation of signaling
1.14	4.05e-02	GO:0048869	cellular developmental process
1.21	4.32e-02	GO:0042127	regulation of cell proliferation
1.56	4.40e-02	GO:0030111	regulation of Wnt receptor signaling pathway
1.98	4.43e-02	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.14	3.32e-75	GO:0005622	intracellular
1.15	2.50e-72	GO:0044424	intracellular part
1.17	3.87e-52	GO:0043231	intracellular membrane-bounded organelle
1.17	4.01e-52	GO:0043227	membrane-bounded organelle
1.15	2.72e-51	GO:0043226	organelle
1.15	3.79e-51	GO:0043229	intracellular organelle
1.24	2.76e-46	GO:0005634	nucleus
1.15	4.03e-37	GO:0005737	cytoplasm
1.32	2.11e-24	GO:0044428	nuclear part
1.05	6.11e-22	GO:0005623	cell
1.05	8.73e-22	GO:0044464	cell part
1.17	4.43e-21	GO:0044446	intracellular organelle part
1.33	5.49e-21	GO:0031981	nuclear lumen
1.29	5.24e-20	GO:0070013	intracellular organelle lumen
1.16	1.78e-19	GO:0044422	organelle part
1.27	9.82e-19	GO:0031974	membrane-enclosed lumen
1.27	1.35e-18	GO:0043233	organelle lumen
1.28	1.91e-17	GO:0005829	cytosol
1.14	2.26e-17	GO:0044444	cytoplasmic part
1.35	8.30e-17	GO:0005654	nucleoplasm
1.43	8.47e-10	GO:0005694	chromosome
1.17	4.99e-08	GO:0043228	non-membrane-bounded organelle
1.17	4.99e-08	GO:0043232	intracellular non-membrane-bounded organelle
1.35	6.27e-08	GO:0044451	nucleoplasm part
1.43	7.70e-08	GO:0044427	chromosomal part
1.14	2.54e-07	GO:0032991	macromolecular complex
1.55	2.49e-06	GO:0000785	chromatin
1.14	5.73e-06	GO:0043234	protein complex
1.59	2.03e-05	GO:0031252	cell leading edge
1.86	4.39e-05	GO:0000790	nuclear chromatin
1.50	2.71e-04	GO:0000228	nuclear chromosome
1.73	1.01e-03	GO:0016585	chromatin remodeling complex
1.52	1.22e-03	GO:0044454	nuclear chromosome part
1.16	5.09e-03	GO:0012505	endomembrane system
1.34	5.85e-03	GO:0048471	perinuclear region of cytoplasm
1.77	6.95e-03	GO:0034399	nuclear periphery
1.13	1.41e-02	GO:0031090	organelle membrane
1.27	1.43e-02	GO:0005730	nucleolus
1.49	2.06e-02	GO:0031965	nuclear membrane
1.75	2.60e-02	GO:0016363	nuclear matrix
1.36	3.52e-02	GO:0005635	nuclear envelope
1.31	4.27e-02	GO:0005815	microtubule organizing center
1.48	4.37e-02	GO:0000151	ubiquitin ligase complex
1.87	4.66e-02	GO:0000792	heterochromatin
1.46	4.92e-02	GO:0005912	adherens junction

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.20	4.25e-49	GO:0005515	protein binding
1.10	1.71e-35	GO:0005488	binding
1.26	5.22e-16	GO:0000166	nucleotide binding
1.18	1.35e-12	GO:0003676	nucleic acid binding
1.36	3.74e-11	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.24	6.41e-11	GO:0035639	purine ribonucleoside triphosphate binding
1.23	1.81e-10	GO:0017076	purine nucleotide binding
1.24	1.99e-10	GO:0032553	ribonucleotide binding
1.24	1.99e-10	GO:0032555	purine ribonucleotide binding
1.33	3.24e-10	GO:0030528	transcription regulator activity
1.36	1.71e-09	GO:0016301	kinase activity
1.36	1.01e-08	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.19	1.54e-08	GO:0003677	DNA binding
1.24	3.34e-08	GO:0030554	adenyl nucleotide binding
1.24	4.33e-08	GO:0005524	ATP binding
1.24	4.84e-08	GO:0032559	adenyl ribonucleotide binding
1.35	1.25e-07	GO:0043565	sequence-specific DNA binding
1.47	2.06e-07	GO:0000988	protein binding transcription factor activity
1.47	2.06e-07	GO:0000989	transcription factor binding transcription factor activity
1.47	3.07e-07	GO:0003712	transcription cofactor activity
1.37	3.09e-07	GO:0004672	protein kinase activity
1.21	8.62e-07	GO:0016740	transferase activity
1.30	2.01e-06	GO:0003723	RNA binding
1.31	2.60e-06	GO:0019899	enzyme binding
1.41	2.86e-06	GO:0019904	protein domain specific binding
1.40	5.70e-06	GO:0004674	protein serine/threonine kinase activity
1.49	2.72e-05	GO:0016881	acid-amino acid ligase activity
1.45	5.85e-05	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.52	7.43e-05	GO:0003713	transcription coactivator activity
1.61	1.09e-04	GO:0004721	phosphoprotein phosphatase activity
1.24	1.58e-04	GO:0001071	nucleic acid binding transcription factor activity
1.24	1.58e-04	GO:0003700	sequence-specific DNA binding transcription factor activity
1.34	2.84e-04	GO:0016874	ligase activity
1.47	6.69e-04	GO:0019787	small conjugating protein ligase activity
1.41	8.28e-04	GO:0008134	transcription factor binding
1.45	9.83e-04	GO:0016791	phosphatase activity
1.39	1.14e-03	GO:0016563	transcription activator activity
1.31	3.62e-03	GO:0030695	GTPase regulator activity
1.45	3.81e-03	GO:0004842	ubiquitin-protein ligase activity
1.30	4.96e-03	GO:0060589	nucleoside-triphosphatase regulator activity
1.47	5.12e-03	GO:0010843	promoter binding
1.45	6.39e-03	GO:0000975	regulatory region DNA binding
1.45	6.39e-03	GO:0001067	regulatory region nucleic acid binding
1.45	6.39e-03	GO:0044212	transcription regulatory region DNA binding
1.08	9.54e-03	GO:0003824	catalytic activity
1.36	1.05e-02	GO:0016564	transcription repressor activity
1.46	1.07e-02	GO:0003682	chromatin binding
1.23	1.46e-02	GO:0042802	identical protein binding
1.26	2.27e-02	GO:0008092	cytoskeletal protein binding
1.19	4.22e-02	GO:0030234	enzyme regulator activity
1.89	4.58e-02	GO:0046332	SMAD binding
1.29	4.81e-02	GO:0008047	enzyme activator activity